Danio rerio

61 known processes

nr5a2

nuclear receptor subfamily 5, group A, member 2

(Aliases: ff1a,zFF1A,zFF1B,ftz,ftzf1,zFF1,sf1)

nr5a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecule biosynthetic processGO:00090592270.525
larval developmentGO:000216420.523
Worm
regulation of transcription dna templatedGO:00063552130.408
segmentationGO:0035282970.385
Fly
positive regulation of gene expressionGO:0010628710.353
Human Zebrafish Mouse Fly
positive regulation of rna biosynthetic processGO:1902680570.335
Human Zebrafish Mouse Fly
agingGO:000756820.291
cellular nitrogen compound biosynthetic processGO:00442712180.290
regulation of cellular biosynthetic processGO:00313262450.287
cellular aromatic compound metabolic processGO:00067252950.233
lipid storageGO:001991510.214
Worm
aromatic compound biosynthetic processGO:00194382170.188
biosynthetic processGO:00090582940.183
regulation of nucleobase containing compound metabolic processGO:00192192500.181
heart developmentGO:00075073130.173
regulation of cellular macromolecule biosynthetic processGO:20001122220.170
morphogenesis of an epitheliumGO:00020093330.138
response to hormoneGO:0009725480.129
Fly
establishment of localizationGO:00512342440.126
negative regulation of protein kinase activityGO:000646940.122
regulation of macromolecule biosynthetic processGO:00105562250.115
regionalizationGO:00030022740.115
Fly
urogenital system developmentGO:0001655970.115
regulation of rna biosynthetic processGO:20011412130.111
rna biosynthetic processGO:00327741810.109
rna metabolic processGO:00160702190.105
muscle tissue developmentGO:00605371100.102
positive regulation of metabolic processGO:00098931080.099
Human Zebrafish Mouse Fly
cellular response to molecule of bacterial originGO:007121930.099
regulation of cellular metabolic processGO:00313233200.094
nucleobase containing compound biosynthetic processGO:00346542050.094
nucleobase containing compound metabolic processGO:00061392740.091
transcription from rna polymerase ii promoterGO:0006366800.091
Zebrafish Mouse Rat Fly
cognitionGO:005089010.091
intracellular receptor signaling pathwayGO:0030522300.088
Rat Fly
organic substance biosynthetic processGO:19015762890.088
regulation of multicellular organismal processGO:00512392770.086
Worm
positive regulation of cellular biosynthetic processGO:0031328680.084
Human Zebrafish Mouse Fly
embryonic pattern specificationGO:0009880440.084
Fly
positive regulation of nitrogen compound metabolic processGO:0051173690.081
Human Zebrafish Mouse Fly
cellular nitrogen compound metabolic processGO:00346412900.079
maintenance of locationGO:005123540.076
Worm
positive regulation of cellular metabolic processGO:0031325940.076
Human Zebrafish Mouse Fly
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.073
gene expressionGO:00104672520.071
kidney developmentGO:0001822920.071
developmental programmed cell deathGO:001062340.068
anterior posterior pattern specificationGO:00099521520.067
cardiac chamber developmentGO:0003205190.067
patterning of blood vesselsGO:0001569150.067
localization of cellGO:00516742440.066
Worm
head developmentGO:00603223030.065
Zebrafish Fly
somitogenesisGO:0001756870.064
periodic partitioningGO:000736510.062
Fly
regulation of reproductive processGO:200024140.060
connective tissue developmentGO:0061448990.060
hepaticobiliary system developmentGO:0061008980.060
nitrogen compound metabolic processGO:00068073190.059
positive regulation of rna metabolic processGO:0051254590.058
Human Zebrafish Mouse Fly
nucleic acid templated transcriptionGO:00976591810.058
mesenchyme developmentGO:00604851270.058
chordate embryonic developmentGO:00430092710.057
outflow tract morphogenesisGO:000315110.057
regulation of epithelial cell proliferationGO:005067830.057
programmed cell deathGO:00125011190.056
Worm
regulation of biosynthetic processGO:00098892500.056
somite developmentGO:0061053960.055
regulation of organ growthGO:004662030.055
cellular response to endogenous stimulusGO:0071495680.055
Fly
regulation of rna metabolic processGO:00512522240.054
hemopoiesisGO:00300971830.054
positive regulation of striated muscle cell differentiationGO:005115510.054
cell projection morphogenesisGO:00488582440.053
Fly
cell motilityGO:00488702440.053
Worm
negative regulation of kinase activityGO:003367340.051
heterocycle metabolic processGO:00464832900.051
nitric oxide mediated signal transductionGO:000726320.051
cardiac chamber morphogenesisGO:0003206120.049
cardiac chamber formationGO:000320740.049
lipid homeostasisGO:005508830.049
Mouse Fly
cellular macromolecule metabolic processGO:00442603910.049
response to other organismGO:0051707970.048
positive regulation of biological processGO:00485182530.048
Human Zebrafish Mouse Worm Fly
gland developmentGO:00487321430.048
Zebrafish
phagocytosisGO:000690930.047
positive regulation of transcription dna templatedGO:0045893570.046
Human Zebrafish Mouse Fly
heterocycle biosynthetic processGO:00181302150.046
cellular biosynthetic processGO:00442492860.046
cellular response to biotic stimulusGO:007121630.045
cellular component morphogenesisGO:00329893360.045
Fly
striated muscle cell differentiationGO:00511461290.045
cellular response to lipopolysaccharideGO:007122230.044
cellular macromolecule biosynthetic processGO:00346452240.044
transcription dna templatedGO:00063511810.043
regulation of cell developmentGO:00602841000.043
positive regulation of nucleic acid templated transcriptionGO:1903508570.043
Human Zebrafish Mouse Fly
regulation of transcription from rna polymerase ii promoterGO:00063571140.042
Zebrafish Mouse Rat Fly
positive regulation of cellular amine metabolic processGO:003324000.042
ventricular cardiac muscle tissue morphogenesisGO:005501020.041
nucleic acid metabolic processGO:00903042440.041
regulation of protein localization to nucleusGO:190018020.041
cardiac muscle cell differentiationGO:0055007300.041
positive regulation of macromolecule biosynthetic processGO:0010557590.041
Human Zebrafish Mouse Fly
cellular response to estrogen stimulusGO:0071391240.039
embryonic limb morphogenesisGO:003032620.039
negative regulation of protein phosphorylationGO:000193340.038
regulation of heart growthGO:006042020.037
signal transductionGO:00071654550.037
Rat Fly
single organism metabolic processGO:00447102170.036
Mouse
central nervous system developmentGO:00074173870.036
Zebrafish Fly
organic cyclic compound biosynthetic processGO:19013622230.036
vestibular receptor cell differentiationGO:006011430.036
regulation of primary metabolic processGO:00800903110.036
nucleocytoplasmic transportGO:000691340.036
endocardium formationGO:006021410.035
regulation of localizationGO:00328791040.035
liver developmentGO:0001889960.034
heart processGO:0003015710.034
positive regulation of muscle organ developmentGO:004863610.034
ventral spinal cord interneuron fate commitmentGO:006057930.034
stem cell differentiationGO:00488631170.034
carboxylic acid metabolic processGO:0019752220.034
Mouse
positive regulation of muscle cell differentiationGO:005114910.034
rhombomere 5 developmentGO:002157140.034
dendrite guidanceGO:007098300.034
glomerulus developmentGO:0032835270.033
multicellular organismal response to stressGO:003355520.033
response to vitaminGO:003327330.033
cardiocyte differentiationGO:0035051440.032
regulation of nucleic acid templated transcriptionGO:19035062130.032
female sex differentiationGO:004666040.032
response to biotic stimulusGO:0009607970.032
retinoic acid receptor signaling pathwayGO:0048384160.032
nuclear transportGO:005116940.031
regulation of stem cell differentiationGO:200073640.031
positive regulation of striated muscle tissue developmentGO:004584410.031
embryonic organ developmentGO:00485683810.030
anterior commissure morphogenesisGO:002196030.030
stem cell proliferationGO:007208940.029
response to alkaloidGO:004327920.029
vasculature developmentGO:00019442780.029
homeostatic processGO:00425921420.029
Mouse Fly
organic cyclic compound metabolic processGO:19013603010.028
regulation of cell activationGO:005086510.028
digestive system developmentGO:00551232890.028
lateral inhibitionGO:004633110.028
heart morphogenesisGO:00030071560.028
apoptotic process involved in developmentGO:190274220.028
cell substrate adhesionGO:003158940.028
nephron developmentGO:0072006310.028
glial cell fate specificationGO:002178040.028
apoptotic process involved in morphogenesisGO:006056120.027
digestive tract morphogenesisGO:00485462310.027
regulation of stem cell proliferationGO:007209120.027
response to antibioticGO:004667710.027
tissue remodelingGO:004877140.027
regulation of nitrogen compound metabolic processGO:00511712510.027
nephron tubule morphogenesisGO:007207810.027
cellular component assemblyGO:00226071700.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
regulation of dna replicationGO:000627530.026
neuron fate commitmentGO:0048663260.026
single organism localizationGO:19025782250.026
protein localization to nucleusGO:003450430.026
positive regulation of cell cycleGO:004578730.026
response to steroid hormoneGO:0048545350.026
response to endogenous stimulusGO:0009719830.026
Fly
multi organism reproductive processGO:0044703360.025
Worm
cilium morphogenesisGO:0060271850.025
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.025
Zebrafish Mouse Fly
hepatocyte differentiationGO:007036510.025
negative regulation of stem cell differentiationGO:200073720.025
growthGO:00400071740.025
Worm
b cell activationGO:004211320.025
heart contractionGO:0060047710.025
organelle organizationGO:00069962270.025
intracellular estrogen receptor signaling pathwayGO:003052030.025
catechol containing compound biosynthetic processGO:000971320.025
erk1 and erk2 cascadeGO:007037140.024
cellular response to organic substanceGO:00713101050.024
Fly
cerebellar granular layer formationGO:002168430.024
myeloid cell homeostasisGO:0002262560.024
synaptic target recognitionGO:000803910.024
midbrain developmentGO:0030901280.024
response to vitamin b3GO:003355220.024
negative regulation of apoptotic processGO:0043066550.024
regulation of macromolecule metabolic processGO:00602553170.024
alpha amino acid metabolic processGO:190160530.024
neuron fate determinationGO:004866420.024
proximal distal pattern formationGO:000995410.024
response to drugGO:004249330.024
negative regulation of macromolecule biosynthetic processGO:0010558480.024
regulation of intracellular protein transportGO:003315730.023
multicellular organism growthGO:003526440.023
Worm
otolith morphogenesisGO:003247480.023
negative regulation of protein serine threonine kinase activityGO:007190120.023
muscle structure developmentGO:00610611960.023
rhombomere 5 morphogenesisGO:002166410.023
regulation of bone remodelingGO:004685020.023
peptidyl serine modificationGO:001820920.022
muscle organ developmentGO:00075171010.022
response to estrogenGO:0043627270.022
muscle cell differentiationGO:00426921390.022
regulation of protein transportGO:005122330.022
ventral spinal cord developmentGO:0021517350.022
cellular response to antibioticGO:007123610.022
cell fate specification involved in pattern specificationGO:006057330.022
optic placode formation involved in camera type eye formationGO:004661930.021
cellular component biogenesisGO:00440851780.021
rhombomere 6 developmentGO:002157240.021
negative regulation of epithelial cell proliferationGO:005068010.021
columnar cuboidal epithelial cell differentiationGO:0002065380.021
positive regulation of biosynthetic processGO:0009891680.021
Human Zebrafish Mouse Fly
stem cell developmentGO:0048864820.021
macromolecule localizationGO:0033036540.021
Worm
response to ketoneGO:190165410.021
blood vessel developmentGO:00015682460.021
response to nutrientGO:000758430.020
cardiac muscle tissue developmentGO:0048738480.020
peptidyl serine phosphorylationGO:001810510.020
neuron neuron synaptic transmissionGO:000727010.020
pancreas developmentGO:0031016840.020
Zebrafish
skeletal muscle thin filament assemblyGO:003024040.020
renal system developmentGO:0072001940.020
response to cadmium ionGO:0046686140.020
cellular response to extracellular stimulusGO:003166820.020
regulation of establishment of protein localizationGO:007020140.020
single organism organelle organizationGO:19025891990.020
muscle cell fate determinationGO:000752110.020
positive regulation of cell activationGO:005086710.020
neuroblast differentiationGO:001401610.020
positive regulation of cellular component biogenesisGO:004408930.019
rhombomere morphogenesisGO:0021593170.019
establishment of protein localization to organelleGO:007259440.019
negative regulation of neural precursor cell proliferationGO:200017810.019
ventricular cardiac muscle tissue developmentGO:000322930.019
response to inorganic substanceGO:0010035380.019
extrinsic apoptotic signaling pathwayGO:009719130.019
lipid catabolic processGO:001604240.019
deathGO:00162651210.019
Worm
regulation of tissue remodelingGO:003410320.019
cardiac atrium morphogenesisGO:000320920.019
behaviorGO:0007610740.019
Worm Fly
mesenchymal cell developmentGO:0014031780.019
negative regulation of metabolic processGO:0009892860.019
negative regulation of macromolecule metabolic processGO:0010605760.019
regulation of dna templated transcription elongationGO:003278430.019
photoreceptor cell fate specificationGO:004370410.018
regulation of cellular ketone metabolic processGO:001056570.018
protein import into nucleusGO:000660630.018
response to external biotic stimulusGO:0043207970.018
regulation of receptor activityGO:001046920.018
cell matrix adhesionGO:000716040.018
positive regulation of muscle tissue developmentGO:190186310.018
cardiac cell developmentGO:0055006210.018
regulation of cytoplasmic transportGO:190364940.018
camera type eye morphogenesisGO:00485931080.018
positive regulation of translationGO:004572710.018
positive regulation of erk1 and erk2 cascadeGO:007037420.018
cell projection assemblyGO:0030031640.018
neural crest cell developmentGO:0014032620.018
mitochondrion organizationGO:000700540.018
response to stressGO:00069502630.018
cellular ketone metabolic processGO:0042180110.018
homeostasis of number of cellsGO:0048872620.017
positive regulation of epithelial cell proliferationGO:005067910.017
developmental growth involved in morphogenesisGO:0060560860.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
bone remodelingGO:004684920.017
chemotaxisGO:00069351040.017
cardiac cell fate commitmentGO:006091110.017
regulation of cell substrate adhesionGO:001081010.017
catechol containing compound metabolic processGO:000971220.017
sensory organ developmentGO:00074233930.017
positive regulation of secretionGO:005104710.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
hepatocyte proliferationGO:007257420.017
regulation of cardiac muscle tissue developmentGO:005502410.017
response to chemicalGO:00422213200.017
Fly
type b pancreatic cell developmentGO:000332340.017
apoptotic processGO:00069151160.017
Worm
embryonic digestive tract developmentGO:004856640.016
regulation of protein complex assemblyGO:004325430.016
intracellular steroid hormone receptor signaling pathwayGO:003051850.016
regulation of protein targetingGO:190353320.016
regulation of apoptotic processGO:0042981980.016
intracellular signal transductionGO:0035556850.016
regulation of blood pressureGO:000821710.016
negative regulation of cellular processGO:00485232830.016
axonogenesisGO:00074091520.016
cerebellar granular layer morphogenesisGO:002168330.016
multi organism cellular processGO:004476420.016
Human
cellular response to organic cyclic compoundGO:0071407380.016
hematopoietic stem cell differentiationGO:0060218200.016
positive regulation of leukocyte differentiationGO:190210710.016
endocrine system developmentGO:0035270650.016
Zebrafish
regulation of cell deathGO:00109411030.016
nephron morphogenesisGO:007202820.016
negative regulation of programmed cell deathGO:0043069580.015
morphogenesis of an epithelial sheetGO:0002011490.015
lymphocyte proliferationGO:004665110.015
regulation of multicellular organism growthGO:004001440.015
Worm
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.015
photoreceptor cell fate commitmentGO:004655210.015
positive regulation of macromolecule metabolic processGO:0010604930.015
Human Zebrafish Mouse Fly
dopamine biosynthetic processGO:004241620.015
oxoacid metabolic processGO:0043436310.015
Mouse
membrane lipid biosynthetic processGO:004646720.015
negative regulation of protein transportGO:005122430.015
adult behaviorGO:003053420.015
cellular amine metabolic processGO:004410620.015
brain developmentGO:00074202930.015
Zebrafish Fly
ceramide biosynthetic processGO:004651310.015
negative regulation of cell deathGO:0060548600.015
regulation of metabolic processGO:00192223590.015
oligodendrocyte cell fate specificationGO:002177840.015
anatomical structure homeostasisGO:0060249360.015
enteroendocrine cell differentiationGO:003588390.015
amine metabolic processGO:000930820.015
regulation of cell motilityGO:2000145460.015
exocrine system developmentGO:0035272280.015
meiotic nuclear divisionGO:000712640.015
negative regulation of cytokine productionGO:000181810.015
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
Human Zebrafish Mouse Fly
mesenchymal cell differentiationGO:0048762870.015
peptide transportGO:001583310.015
regulation of cell communicationGO:00106462320.015
regulation of neurological system processGO:003164420.014
leukocyte differentiationGO:0002521250.014
neuronal stem cell maintenanceGO:009715020.014
negative regulation of signal transduction in absence of ligandGO:190109910.014
organic substance transportGO:0071702580.014
regulation of erk1 and erk2 cascadeGO:007037240.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
Fly
cell projection organizationGO:00300302840.014
Fly
energy homeostasisGO:009700930.014
organ growthGO:0035265120.014
regulation of biomineral tissue developmentGO:007016720.014
positive regulation of transportGO:005105020.014
atrioventricular valve formationGO:000319030.014
sensory organ morphogenesisGO:00905962000.014
immune system developmentGO:00025201910.014
post embryonic morphogenesisGO:000988640.014
Fly
posterior lateral line system developmentGO:0048915460.014
monovalent inorganic cation transportGO:0015672420.014
regulation of anatomical structure morphogenesisGO:00226031300.014
viral processGO:001603210.014
Human
cell deathGO:00082191210.013
Worm
ear developmentGO:00435831270.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
endodermal digestive tract morphogenesisGO:006103120.013
positive regulation of secretion by cellGO:190353210.013
gland morphogenesisGO:0022612130.013
regulation of production of molecular mediator of immune responseGO:000270010.013
negative regulation of transcription dna templatedGO:0045892450.013
central nervous system neuron developmentGO:0021954290.013
small molecule metabolic processGO:0044281770.013
Mouse
axon developmentGO:00615641660.013
neuron projection morphogenesisGO:00488121610.013
Fly
chemosensory behaviorGO:000763510.013
Fly
embryonic heart tube developmentGO:00350501330.013
regulation of myotube differentiationGO:001083020.013
epithelial cell proliferation involved in liver morphogenesisGO:007257520.013
venous blood vessel morphogenesisGO:004884530.013
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
regulation of endothelial cell differentiationGO:004560130.013
modification dependent protein catabolic processGO:001994130.013
organelle assemblyGO:00709251100.013
negative regulation of mapk cascadeGO:004340940.013
camera type eye photoreceptor cell differentiationGO:0060219190.013
mononuclear cell proliferationGO:003294310.013
developmental maturationGO:0021700340.013
cell morphogenesisGO:00009022890.013
Fly
cranial suture morphogenesisGO:006036310.013
leukocyte proliferationGO:007066110.013
positive regulation of map kinase activityGO:004340630.013
neural tube patterningGO:0021532330.013
leukocyte homeostasisGO:000177620.012
aorta morphogenesisGO:003590930.012
nuclear importGO:005117030.012
cell substrate junction assemblyGO:000704420.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
rna localizationGO:000640340.012
cell surface receptor signaling pathwayGO:00071663250.012
embryonic heart tube formationGO:000314410.012
response to molecule of bacterial originGO:0002237140.012
rostrocaudal neural tube patterningGO:0021903290.012
cellular response to toxic substanceGO:009723710.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
morphogenesis of a branching structureGO:0001763210.012
response to hexoseGO:000974630.012
locomotionGO:00400113130.012
Worm
epithelial cell developmentGO:0002064420.012
branching morphogenesis of a nerveGO:004875540.012
protein importGO:001703830.012
otolith developmentGO:0048840320.012
determination of left right symmetryGO:00073681790.011
stem cell fate commitmentGO:004886510.011
motor neuron axon guidanceGO:0008045230.011
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of sarcomere organizationGO:006029720.011
dna templated transcription elongationGO:000635430.011
cellular response to radiationGO:007147840.011
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225350.011
regulation of programmed cell deathGO:00430671010.011
response to oxygen containing compoundGO:1901700550.011
cell differentiation in spinal cordGO:0021515400.011
regulation of cell proliferationGO:0042127370.011
Mouse
glandular epithelial cell differentiationGO:000206790.011
negative regulation of catabolic processGO:000989530.011
cellular lipid metabolic processGO:0044255360.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of sodium ion transportGO:000202820.011
ovulation cycle processGO:002260220.011
regulation of organ morphogenesisGO:2000027350.011
negative regulation of biosynthetic processGO:0009890550.011
regulation of cellular phGO:003064110.011
regulation of autophagyGO:001050630.011
positive regulation of dna metabolic processGO:005105410.011
regulation of dendrite developmentGO:005077330.011
positive regulation of immune effector processGO:000269930.011
pancreatic a cell developmentGO:000332220.011
regulation of gene expressionGO:00104682650.011
lymphocyte homeostasisGO:000226010.011
fatty acid transportGO:001590810.011
lateral line system developmentGO:0048925760.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.011
midbrain hindbrain boundary developmentGO:0030917230.011
neuroblast fate commitmentGO:001401710.010
cell cycle g1 s phase transitionGO:004484310.010
circadian sleep wake cycleGO:004274520.010
regulation of cellular amine metabolic processGO:003323800.010
catecholamine biosynthetic processGO:004242320.010
dopamine metabolic processGO:004241720.010
nerve developmentGO:0021675450.010
cardiac muscle cell developmentGO:0055013200.010
camera type eye developmentGO:00430102220.010
regulation of growth rateGO:004000910.010
rhombomere developmentGO:0021546190.010
embryonic camera type eye developmentGO:0031076290.010
nuclear exportGO:005116810.010
striated muscle tissue developmentGO:00147061100.010
long chain fatty acid transportGO:001590910.010
foregut morphogenesisGO:000744040.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
negative regulation of map kinase activityGO:004340720.010
negative regulation of dna replicationGO:000815620.010

nr5a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.050
disease of cellular proliferationDOID:1456600.050
cancerDOID:16200.050
musculoskeletal system diseaseDOID:1700.038
connective tissue diseaseDOID:6500.038
bone diseaseDOID:008000100.038
disease of anatomical entityDOID:700.038
disease of metabolismDOID:001466700.017
endocrine system diseaseDOID:2800.016