Danio rerio

39 known processes

upf1

upf1 regulator of nonsense transcripts homolog (yeast)

(Aliases: wu:fj48a01,wu:fi40f07,zgc:55472,rent1)

upf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.856
cellular macromolecule metabolic processGO:00442603910.583
mrna catabolic processGO:000640260.538
nuclear transcribed mrna catabolic processGO:000095640.424
rna catabolic processGO:000640170.297
regulation of cellular metabolic processGO:00313233200.253
Human
nucleic acid metabolic processGO:00903042440.252
rna metabolic processGO:00160702190.243
organelle organizationGO:00069962270.220
regulation of nitrogen compound metabolic processGO:00511712510.199
organic substance catabolic processGO:1901575280.189
nucleobase containing compound metabolic processGO:00061392740.170
larval developmentGO:000216420.160
embryo development ending in birth or egg hatchingGO:00097922710.156
regulation of macromolecule metabolic processGO:00602553170.147
Human Mouse Worm
signal transductionGO:00071654550.144
nucleic acid templated transcriptionGO:00976591810.138
heterocycle metabolic processGO:00464832900.130
cellular aromatic compound metabolic processGO:00067252950.127
regulation of rna biosynthetic processGO:20011412130.127
response to chemicalGO:00422213200.125
regulation of nucleobase containing compound metabolic processGO:00192192500.123
regulation of rna metabolic processGO:00512522240.116
regulation of macromolecule biosynthetic processGO:00105562250.116
Human
regulation of establishment of protein localizationGO:007020140.116
establishment of localizationGO:00512342440.115
nuclear transportGO:005116940.106
organic cyclic compound metabolic processGO:19013603010.105
mrna metabolic processGO:0016071200.096
cellular ketone metabolic processGO:0042180110.092
regulation of oocyte developmentGO:006028130.092
positive regulation of transportGO:005105020.088
regulation of metabolic processGO:00192223590.087
Human Mouse Worm
cellular nitrogen compound metabolic processGO:00346412900.086
embryonic organ developmentGO:00485683810.086
Worm
peptidyl serine phosphorylationGO:001810510.085
cellular nitrogen compound biosynthetic processGO:00442712180.084
positive regulation of signal transductionGO:0009967560.083
maintenance of locationGO:005123540.083
agingGO:000756820.082
regulation of cellular biosynthetic processGO:00313262450.082
Human
macromolecule biosynthetic processGO:00090592270.080
Human
nitrogen compound metabolic processGO:00068073190.080
tube morphogenesisGO:00352393490.078
regulation of gene expressionGO:00104682650.078
Human Mouse Worm
meiotic nuclear divisionGO:000712640.078
regulation of primary metabolic processGO:00800903110.077
Human
axon developmentGO:00615641660.077
locomotionGO:00400113130.077
neuroblast proliferationGO:000740520.076
modification dependent protein catabolic processGO:001994130.075
regulation of mrna splicing via spliceosomeGO:004802430.074
nucleocytoplasmic transportGO:000691340.074
negative regulation of signal transductionGO:0009968940.073
regulation of signal transductionGO:00099662250.071
rna splicingGO:0008380160.071
proteolysis involved in cellular protein catabolic processGO:005160330.070
rna biosynthetic processGO:00327741810.070
peptidyl serine modificationGO:001820920.066
positive regulation of biological processGO:00485182530.065
cellular component biogenesisGO:00440851780.064
regulation of protein catabolic processGO:004217610.062
regulation of nucleic acid templated transcriptionGO:19035062130.061
cellular protein catabolic processGO:004425740.060
regulation of response to stimulusGO:00485832690.059
regulation of nucleocytoplasmic transportGO:004682220.059
neuron differentiationGO:00301823530.059
negative regulation of biological processGO:00485193040.059
Worm
growthGO:00400071740.058
positive regulation of cellular processGO:00485222010.057
alternative mrna splicing via spliceosomeGO:000038010.056
cellular macromolecule biosynthetic processGO:00346452240.055
Human
modification dependent macromolecule catabolic processGO:004363230.055
regulation of protein targetingGO:190353320.055
regulation of cellular ketone metabolic processGO:001056570.055
chordate embryonic developmentGO:00430092710.054
nucleobase containing compound biosynthetic processGO:00346542050.054
protein localization to nucleusGO:003450430.054
cellular amine metabolic processGO:004410620.054
generation of neuronsGO:00486993850.052
regulation of protein transportGO:005122330.052
regulation of mrna processingGO:005068430.052
regulation of transcription from rna polymerase iii promoterGO:000635910.052
regulation of intracellular protein transportGO:003315730.050
regulation of multicellular organismal processGO:00512392770.049
cellular catabolic processGO:0044248270.048
transportGO:00068102200.048
transcription dna templatedGO:00063511810.048
regulation of meiotic cell cycleGO:005144510.048
cellular component movementGO:00069283350.048
cell surface receptor signaling pathwayGO:00071663250.048
gene expressionGO:00104672520.047
Human Mouse Worm
single organism reproductive processGO:0044702400.047
Worm
single organism organelle organizationGO:19025891990.046
organic cyclic compound biosynthetic processGO:19013622230.045
fertilizationGO:000956630.045
neuron developmentGO:00486662620.045
positive regulation of cellular metabolic processGO:0031325940.045
cartilage developmentGO:0051216960.045
regulation of alternative mrna splicing via spliceosomeGO:000038110.045
lateral inhibitionGO:004633110.045
cellular response to organic substanceGO:00713101050.044
regulation of cellular protein catabolic processGO:190336210.044
regionalizationGO:00030022740.043
regulation of protein ubiquitinationGO:003139630.043
regulation of cellular amine metabolic processGO:003323800.043
regulation of cellular macromolecule biosynthetic processGO:20001122220.042
Human
amine metabolic processGO:000930820.042
response to stressGO:00069502630.042
Human
positive regulation of catabolic processGO:000989640.042
carboxylic acid metabolic processGO:0019752220.042
single organism localizationGO:19025782250.042
regulation of developmental processGO:00507932470.041
tube closureGO:006060610.041
regulation of cellular component organizationGO:0051128860.041
Human
response to endogenous stimulusGO:0009719830.040
digestive tract mesoderm developmentGO:000750210.040
organic substance biosynthetic processGO:19015762890.039
Human
lipid storageGO:001991510.038
protein complex biogenesisGO:0070271300.038
regulation of cellular amino acid metabolic processGO:000652100.038
phosphorus metabolic processGO:00067931090.038
Human
phagocytosisGO:000690930.037
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.037
establishment of protein localization to organelleGO:007259440.037
regulation of transcription from rna polymerase ii promoterGO:00063571140.037
digestive system developmentGO:00551232890.036
multicellular organism growthGO:003526440.036
positive regulation of cellular catabolic processGO:003133130.036
negative regulation of chromosome organizationGO:200125110.036
peptidyl threonine phosphorylationGO:001810710.036
positive regulation of nitrogen compound metabolic processGO:0051173690.036
cellular response to extracellular stimulusGO:003166820.036
digestive tract morphogenesisGO:00485462310.035
aromatic compound biosynthetic processGO:00194382170.035
adherens junction maintenanceGO:003433420.035
cellular biosynthetic processGO:00442492860.035
Human
cellular response to nutrient levelsGO:003166920.035
regulation of protein complex assemblyGO:004325430.035
stem cell fate commitmentGO:004886510.034
positive regulation of cellular amine metabolic processGO:003324000.034
mitotic cell cycle processGO:1903047480.034
chemotaxisGO:00069351040.034
regulation of organelle organizationGO:0033043290.033
regulation of response to cytokine stimulusGO:006075930.033
regulation of cell communicationGO:00106462320.033
positive regulation of cell cycleGO:004578730.032
negative regulation of cellular metabolic processGO:0031324770.032
regulation of biosynthetic processGO:00098892500.032
Human
positive regulation of cellular amino acid metabolic processGO:004576400.032
actin cytoskeleton organizationGO:0030036630.031
lipid metabolic processGO:0006629520.031
positive regulation of cell adhesionGO:004578510.031
positive regulation of rna metabolic processGO:0051254590.031
negative regulation of cytoplasmic transportGO:190365020.031
regulation of reproductive processGO:200024140.031
transcription from rna polymerase ii promoterGO:0006366800.031
cellular amino acid metabolic processGO:000652070.030
epithelial tube morphogenesisGO:00605621480.030
response to external stimulusGO:00096052640.030
regulation of protein import into nucleusGO:004230620.030
positive regulation of cellular biosynthetic processGO:0031328680.030
single organism nuclear importGO:190259330.030
positive regulation of response to stimulusGO:0048584800.030
regulation of protein modification by small protein conjugation or removalGO:190332030.029
positive regulation of metabolic processGO:00098931080.029
protein modification processGO:00362111000.029
response to organic substanceGO:00100331530.029
protein importGO:001703830.029
myeloid cell differentiationGO:0030099860.029
cellular response to chemical stimulusGO:00708871570.029
developmental growthGO:00485891660.028
digestive tract developmentGO:00485652650.028
oxoacid metabolic processGO:0043436310.028
cell morphogenesisGO:00009022890.028
cellular macromolecule catabolic processGO:0044265120.028
actin filament polymerizationGO:003004120.028
multi organism reproductive processGO:0044703360.027
organic acid metabolic processGO:0006082310.027
single organism transportGO:00447652060.027
cellular component assemblyGO:00226071700.027
glucose homeostasisGO:004259310.027
positive regulation of cellular component biogenesisGO:004408930.026
ubiquitin dependent protein catabolic processGO:000651130.026
small molecule catabolic processGO:004428230.026
regulation of transcription dna templatedGO:00063552130.026
actin filament based processGO:0030029640.026
synaptic growth at neuromuscular junctionGO:005112420.026
cell migrationGO:00164772370.026
primary neural tube formationGO:001402010.026
transmembrane transportGO:00550851200.025
mitotic cell cycleGO:0000278640.025
negative regulation of protein kinase activityGO:000646940.025
negative regulation of dna metabolic processGO:005105340.025
adult behaviorGO:003053420.025
cell part morphogenesisGO:00329902460.025
protein dephosphorylationGO:000647030.025
heterocycle biosynthetic processGO:00181302150.024
actin polymerization or depolymerizationGO:000815420.024
peptidyl threonine modificationGO:001821010.024
somatic muscle developmentGO:000752540.024
regulation of cytoplasmic transportGO:190364940.024
stem cell maintenanceGO:001982740.024
purine nucleoside monophosphate catabolic processGO:000912840.024
Human
actin filament organizationGO:0007015150.024
localization of cellGO:00516742440.024
macromolecule catabolic processGO:0009057150.024
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
anterior posterior pattern specificationGO:00099521520.023
nuclear importGO:005117030.023
gtp catabolic processGO:000618420.023
small molecule metabolic processGO:0044281770.023
Human
wnt signaling pathwayGO:0016055800.023
peptide transportGO:001583310.023
negative regulation of protein phosphorylationGO:000193340.023
positive regulation of notch signaling pathwayGO:004574730.022
synaptic target recognitionGO:000803910.022
positive regulation of rna biosynthetic processGO:1902680570.022
protein metabolic processGO:00195381830.022
Human
regulation of signalingGO:00230512350.022
adherens junction organizationGO:003433240.022
negative regulation of cellular processGO:00485232830.022
positive regulation of transcription dna templatedGO:0045893570.021
retina development in camera type eyeGO:00600411460.021
ameboidal type cell migrationGO:00016671430.021
macromolecular complex subunit organizationGO:0043933740.021
Human
hindbrain developmentGO:0030902910.021
extrinsic apoptotic signaling pathwayGO:009719130.021
positive regulation of gene expressionGO:0010628710.021
positive regulation of translationGO:004572710.021
single organism metabolic processGO:00447102170.021
Human
positive regulation of nucleic acid templated transcriptionGO:1903508570.021
locomotor rhythmGO:004547530.021
regulation of response to nutrient levelsGO:003210710.021
neuron projection developmentGO:00311751800.021
biosynthetic processGO:00090582940.021
Human
connective tissue developmentGO:0061448990.021
carboxylic acid catabolic processGO:004639530.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
negative regulation of rna metabolic processGO:0051253480.020
negative regulation of histone modificationGO:003105710.020
regulation of multicellular organism growthGO:004001440.020
cellular localizationGO:0051641970.020
fatty acid oxidationGO:001939510.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
pronuclear migrationGO:003504610.020
regulation of nucleoside metabolic processGO:000911820.020
regulation of purine nucleotide catabolic processGO:003312120.020
stem cell developmentGO:0048864820.020
organelle localizationGO:0051640490.020
gtp metabolic processGO:004603940.020
determination of bilateral symmetryGO:00098552040.020
positive regulation of jun kinase activityGO:004350720.019
cell cycle g1 s phase transitionGO:004484310.019
post embryonic organ developmentGO:004856940.019
response to glucoseGO:000974930.019
regulation of fatty acid metabolic processGO:001921710.019
multi organism processGO:00517041340.019
protein targeting to nucleusGO:004474430.019
endodermal cell differentiationGO:0035987190.019
cell projection morphogenesisGO:00488582440.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
membrane invaginationGO:001032410.019
regulation of molecular functionGO:0065009700.019
autophagyGO:000691440.019
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.019
glucose importGO:004632320.019
protein complex assemblyGO:0006461300.019
vesicle mediated transportGO:0016192220.019
spermatid developmentGO:000728620.019
cell cycleGO:0007049930.018
cellular protein modification processGO:00064641000.018
embryonic skeletal joint developmentGO:007249830.018
immune system developmentGO:00025201910.018
negative regulation of nucleobase containing compound metabolic processGO:0045934590.018
regulation of protein localization to nucleusGO:190018020.018
single fertilizationGO:000733830.018
cellular response to external stimulusGO:007149620.018
energy reserve metabolic processGO:000611220.018
regulation of synapse assemblyGO:005196330.018
nuclear migrationGO:000709730.018
negative regulation of cell communicationGO:0010648960.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
specification of symmetryGO:00097992040.018
developmental process involved in reproductionGO:0003006270.017
Worm
cellular response to starvationGO:000926710.017
negative regulation of cellular catabolic processGO:003133030.017
single organism cellular localizationGO:1902580460.017
negative chemotaxisGO:005091910.017
mesenchymal cell developmentGO:0014031780.017
cellular process involved in reproduction in multicellular organismGO:0022412280.017
regulation of rho protein signal transductionGO:003502320.017
skeletal system developmentGO:00015011810.017
mrna splicing via spliceosomeGO:0000398100.017
regulation of apoptotic processGO:0042981980.017
cellular lipid metabolic processGO:0044255360.017
skin developmentGO:0043588540.017
stem cell proliferationGO:007208940.017
response to nutrientGO:000758430.017
macromolecule modificationGO:00434121110.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
gastrulation with mouth forming secondGO:0001702440.017
single organism membrane fusionGO:004480120.017
multicellular organism reproductionGO:0032504350.016
oocyte maturationGO:000155640.016
negative regulation of metabolic processGO:0009892860.016
Worm
organonitrogen compound metabolic processGO:1901564740.016
Human
cell motilityGO:00488702440.016
carbohydrate homeostasisGO:003350010.016
behaviorGO:0007610740.016
positive regulation of protein complex assemblyGO:003133420.016
embryonic skeletal system morphogenesisGO:0048704930.016
cellular protein metabolic processGO:00442671290.016
Human
rna processingGO:0006396250.016
lamellipodium assemblyGO:003003210.016
negative regulation of macromolecule metabolic processGO:0010605760.016
Worm
cardiac cell fate commitmentGO:006091110.016
response to uvGO:000941130.015
negative regulation of map kinase activityGO:004340720.015
sensory organ developmentGO:00074233930.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of response to extracellular stimulusGO:003210410.015
protein import into nucleusGO:000660630.015
establishment of organelle localizationGO:0051656450.015
response to carbohydrateGO:000974330.015
positive regulation of chromosome organizationGO:200125210.015
development of primary female sexual characteristicsGO:004654540.015
wnt signaling pathway planar cell polarity pathwayGO:006007140.015
regulation of cell shapeGO:000836010.015
protein homooligomerizationGO:005126030.015
positive regulation of map kinase activityGO:004340630.015
negative regulation of kinase activityGO:003367340.015
negative regulation of cytokine mediated signaling pathwayGO:000196020.015
macromolecule localizationGO:0033036540.015
canonical wnt signaling pathwayGO:0060070480.015
cellular response to stressGO:0033554620.015
Human
negative regulation of catabolic processGO:000989530.015
sexual reproductionGO:0019953360.015
regulation of biological qualityGO:00650082630.015
eye developmentGO:00016542770.015
regulation of synapse organizationGO:005080730.015
establishment of localization in cellGO:0051649770.014
microtubule cytoskeleton organizationGO:0000226330.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
negative regulation of cytokine productionGO:000181810.014
cellular response to lipopolysaccharideGO:007122230.014
axonogenesisGO:00074091520.014
cytoskeleton organizationGO:0007010960.014
atp catabolic processGO:000620040.014
Human
positive regulation of stress activated mapk cascadeGO:003287430.014
regulation of dendrite developmentGO:005077330.014
response to corticosteroidGO:003196010.014
establishment of apical basal cell polarityGO:003508920.014
response to oxygen containing compoundGO:1901700550.014
negative regulation of stem cell differentiationGO:200073720.014
neuron projection morphogenesisGO:00488121610.014
mrna processingGO:0006397140.014
regulation of type i interferon productionGO:003247920.014
embryonic heart tube developmentGO:00350501330.014
endoderm formationGO:0001706290.014
regulation of gtp catabolic processGO:003312420.014
cellular carbohydrate metabolic processGO:004426240.014
somatic stem cell maintenanceGO:003501910.014
response to alkaloidGO:004327920.014
system processGO:00030081850.014
posttranscriptional regulation of gene expressionGO:0010608140.014
Human Worm
female sex differentiationGO:004666040.014
mitotic dna integrity checkpointGO:004477440.014
erythrocyte differentiationGO:0030218540.014
negative regulation of mitosisGO:004583930.014
cell proliferationGO:0008283800.014
positive regulation of biosynthetic processGO:0009891680.014
positive regulation of signalingGO:0023056560.014
rna splicing via transesterification reactionsGO:0000375100.014
intracellular signal transductionGO:0035556850.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
Human
cellular response to endogenous stimulusGO:0071495680.013
cellular response to molecule of bacterial originGO:007121930.013
female gonad developmentGO:000858540.013
regulation of glucose transportGO:001082710.013
cellular response to biotic stimulusGO:007121630.013
regulation of erk1 and erk2 cascadeGO:007037240.013
protein stabilizationGO:005082120.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
positive regulation of cytoskeleton organizationGO:005149530.013
phosphate containing compound metabolic processGO:00067961080.013
Human
regulation of proteolysisGO:0030162240.013
heart developmentGO:00075073130.013
phosphorylationGO:0016310690.013
hemopoiesisGO:00300971830.013
cellular response to hormone stimulusGO:0032870390.013
appendage morphogenesisGO:0035107560.013
regulation of nucleotide catabolic processGO:003081120.013
angioblast cell migration involved in selective angioblast sproutingGO:003547540.013
meiotic cell cycle processGO:190304630.013
erk1 and erk2 cascadeGO:007037140.012
cell cycle processGO:0022402530.012
negative regulation of nuclear divisionGO:005178430.012
g1 s transition of mitotic cell cycleGO:000008210.012
embryonic organ morphogenesisGO:00485622740.012
Worm
multicellular organismal reproductive processGO:0048609350.012
catabolic processGO:0009056320.012
camera type eye developmentGO:00430102220.012
nuclear divisionGO:0000280230.012
determination of heart left right asymmetryGO:00613711170.012
posttranscriptional gene silencing by rnaGO:003519430.012
Worm
regulation of glucose importGO:004632410.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
macroautophagyGO:001623610.012
regulation of mitotic cell cycleGO:0007346250.012
rna 3 end processingGO:003112320.012
stem cell divisionGO:001714510.012
stem cell differentiationGO:00488631170.012
spermatid differentiationGO:004851520.012
ear morphogenesisGO:0042471640.012
protein localizationGO:0008104400.012
heterocycle catabolic processGO:0046700150.012
positive regulation of glucose transportGO:001082810.012
transcription from rna polymerase iii promoterGO:000638310.011
gene silencing by rnaGO:003104740.011
Worm
phagocytosis engulfmentGO:000691110.011
response to topologically incorrect proteinGO:003596620.011
positive regulation of jnk cascadeGO:004633030.011
negative regulation of cell cycle phase transitionGO:190198850.011
proteasomal protein catabolic processGO:001049820.011
negative regulation of innate immune responseGO:004582420.011
cellular component morphogenesisGO:00329893360.011
regulation of anatomical structure morphogenesisGO:00226031300.011
establishment of monopolar cell polarityGO:006116220.011
regulation of cellular protein metabolic processGO:0032268520.011
Human
nucleoside monophosphate catabolic processGO:000912540.011
Human
embryonic skeletal system developmentGO:0048706970.011
regulation of protein polymerizationGO:003227120.011
regulation of organelle assemblyGO:190211540.011
regulation of establishment or maintenance of cell polarityGO:003287820.011
lipid catabolic processGO:001604240.011
regulation of translational initiationGO:000644610.011
embryonic skeletal joint morphogenesisGO:006027230.011
negative regulation of ras protein signal transductionGO:004658010.011
hormone secretionGO:004687920.011
blood vessel developmentGO:00015682460.011
central nervous system developmentGO:00074173870.011
brain developmentGO:00074202930.011
positive regulation of programmed cell deathGO:0043068290.011
endoderm developmentGO:0007492490.011
cell projection organizationGO:00300302840.011
gastrulationGO:00073692080.011
guanosine containing compound catabolic processGO:190106920.011
notch signaling pathwayGO:0007219350.011
regulation of programmed cell deathGO:00430671010.011
regulation of cell differentiationGO:00455951420.011
sensory organ morphogenesisGO:00905962000.011
response to hormoneGO:0009725480.011
negative regulation of multi organism processGO:004390130.011
protein heterooligomerizationGO:005129110.011
neuroblast differentiationGO:001401610.011
nuclear exportGO:005116810.010
mesenchymal cell differentiationGO:0048762870.010
heart morphogenesisGO:00030071560.010
cell fate commitmentGO:0045165990.010
ovulation cycleGO:004269820.010
establishment of spindle orientationGO:0051294100.010
organophosphate metabolic processGO:0019637370.010
Human
non canonical wnt signaling pathwayGO:0035567130.010
negative regulation of multicellular organismal processGO:0051241690.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
type i interferon productionGO:003260620.010
regulation of synaptic plasticityGO:004816710.010
protein localization to plasma membraneGO:007265910.010
exocrine system developmentGO:0035272280.010
protein complex subunit organizationGO:0071822460.010
Human
regulation of phosphate metabolic processGO:0019220430.010
mrna 3 end processingGO:003112420.010
regulation of wnt signaling pathwayGO:0030111530.010
negative regulation of mapk cascadeGO:004340940.010
negative regulation of chromatin modificationGO:190330910.010
sequestering of metal ionGO:005123830.010
entrainment of circadian clock by photoperiodGO:004315310.010

upf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
disease of metabolismDOID:001466700.010