Danio rerio

0 known processes

eif2c4

eukaryotic translation initiation factor 2C, 4

eif2c4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of neurological system processGO:003164420.428
response to dsrnaGO:004333170.223
cognitionGO:005089010.204
stem cell maintenanceGO:001982740.183
multicellular organism growthGO:003526440.174
regulation of multicellular organism growthGO:004001440.174
periodic partitioningGO:000736510.173
agingGO:000756820.161
metal ion transportGO:0030001580.145
brain developmentGO:00074202930.128
cellular response to dsrnaGO:007135910.125
larval developmentGO:000216420.124
germ line stem cell maintenanceGO:003071820.119
system processGO:00030081850.112
regulation of wound healingGO:006104120.111
single organism localizationGO:19025782250.106
cation transmembrane transportGO:0098655650.102
regulation of gene expressionGO:00104682650.096
cellular nitrogen compound metabolic processGO:00346412900.095
cation transportGO:0006812810.095
stem cell developmentGO:0048864820.095
developmental growthGO:00485891660.090
chordate embryonic developmentGO:00430092710.088
regulation of metabolic processGO:00192223590.087
regionalizationGO:00030022740.077
segment polarity determinationGO:000736710.077
chemosensory behaviorGO:000763510.072
regulation of gene expression epigeneticGO:0040029110.065
generation of neuronsGO:00486993850.061
organic cyclic compound metabolic processGO:19013603010.059
cellular macromolecule metabolic processGO:00442603910.058
cellular response to organic cyclic compoundGO:0071407380.057
heterocycle metabolic processGO:00464832900.057
positive regulation of transportGO:005105020.055
autophagyGO:000691440.054
regulation of macromolecule metabolic processGO:00602553170.053
heterocycle biosynthetic processGO:00181302150.053
striated muscle cell differentiationGO:00511461290.053
regulation of establishment of protein localizationGO:007020140.052
rna processingGO:0006396250.052
rna catabolic processGO:000640170.052
nitrogen compound metabolic processGO:00068073190.050
regulation of behaviorGO:0050795240.050
mrna catabolic processGO:000640260.049
nuclear transportGO:005116940.046
positive regulation of wound healingGO:009030310.046
eye developmentGO:00016542770.045
centrosome organizationGO:005129710.045
response to chemicalGO:00422213200.045
maintenance of locationGO:005123540.044
regulation of protein metabolic processGO:0051246560.044
nucleocytoplasmic transportGO:000691340.044
segmentationGO:0035282970.041
neuromast developmentGO:0048884460.041
single organism metabolic processGO:00447102170.041
cell migrationGO:00164772370.040
dsrna fragmentationGO:003105010.039
cellular component assemblyGO:00226071700.039
cellular response to extracellular stimulusGO:003166820.039
cellular aromatic compound metabolic processGO:00067252950.039
posttranscriptional gene silencingGO:001644130.038
cell substrate adhesionGO:003158940.038
homeostatic processGO:00425921420.038
organic substance biosynthetic processGO:19015762890.038
positive regulation of cell cycleGO:004578730.037
locomotionGO:00400113130.037
gene expressionGO:00104672520.037
skeletal muscle organ developmentGO:0060538780.037
regulation of rna biosynthetic processGO:20011412130.037
ion transportGO:00068111140.036
transportGO:00068102200.036
mrna cleavage involved in gene silencing by mirnaGO:003527910.035
regulation of cellular metabolic processGO:00313233200.035
protein dephosphorylationGO:000647030.035
negative regulation of gene expressionGO:0010629650.035
gene silencing by mirnaGO:003519530.035
regulation of cytoplasmic transportGO:190364940.035
positive regulation of developmental processGO:0051094500.034
negative regulation of catabolic processGO:000989530.033
heart loopingGO:0001947940.033
morphogenesis of an epitheliumGO:00020093330.033
behaviorGO:0007610740.032
regulation of biological qualityGO:00650082630.032
regulation of nitrogen compound metabolic processGO:00511712510.032
protein localization to nucleusGO:003450430.032
cellular macromolecule catabolic processGO:0044265120.032
embryonic pattern specificationGO:0009880440.031
positive regulation of small gtpase mediated signal transductionGO:005105710.031
catabolic processGO:0009056320.031
rna metabolic processGO:00160702190.030
cellular protein metabolic processGO:00442671290.030
single organism transportGO:00447652060.030
response to organic cyclic compoundGO:0014070510.030
cellular response to nutrient levelsGO:003166920.029
small gtpase mediated signal transductionGO:000726480.029
organic substance catabolic processGO:1901575280.029
mrna cleavageGO:000637910.029
embryonic organ morphogenesisGO:00485622740.029
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.029
nucleobase containing compound biosynthetic processGO:00346542050.029
cellular component biogenesisGO:00440851780.029
adult behaviorGO:003053420.029
regulation of response to stimulusGO:00485832690.029
monovalent inorganic cation transportGO:0015672420.028
transcription dna templatedGO:00063511810.028
nucleobase containing compound metabolic processGO:00061392740.028
nucleobase containing compound catabolic processGO:0034655150.028
negative regulation of kinase activityGO:003367340.028
cellular response to chemical stimulusGO:00708871570.027
protein importGO:001703830.027
carbon dioxide transportGO:001567030.027
negative regulation of macromolecule metabolic processGO:0010605760.027
nuclear migrationGO:000709730.027
multi organism processGO:00517041340.027
cellular amine metabolic processGO:004410620.027
negative regulation of nucleic acid templated transcriptionGO:1903507450.027
regulation of autophagyGO:001050630.026
regulation of protein transportGO:005122330.026
nitric oxide biosynthetic processGO:000680920.026
muscle structure developmentGO:00610611960.026
embryonic heart tube developmentGO:00350501330.026
negative regulation of translationGO:001714810.026
cellular macromolecule biosynthetic processGO:00346452240.025
muscle cell developmentGO:00550011150.025
amine metabolic processGO:000930820.025
regulation of transcription dna templatedGO:00063552130.025
protein metabolic processGO:00195381830.025
cellular extravasationGO:004512310.025
microtubule organizing center organizationGO:003102310.025
head developmentGO:00603223030.024
response to nutrientGO:000758430.024
embryonic heart tube morphogenesisGO:00031431080.024
signal transductionGO:00071654550.024
cell projection organizationGO:00300302840.024
cellular response to organic substanceGO:00713101050.024
striated muscle tissue developmentGO:00147061100.024
rna biosynthetic processGO:00327741810.024
nuclear importGO:005117030.024
regulation of cellular amine metabolic processGO:003323800.024
cellular biosynthetic processGO:00442492860.024
embryo development ending in birth or egg hatchingGO:00097922710.024
negative regulation of nitrogen compound metabolic processGO:0051172590.023
mrna processingGO:0006397140.023
nucleic acid templated transcriptionGO:00976591810.023
establishment of localizationGO:00512342440.023
cell morphogenesisGO:00009022890.023
nucleic acid metabolic processGO:00903042440.022
hemopoiesisGO:00300971830.022
aromatic compound biosynthetic processGO:00194382170.022
peptide transportGO:001583310.022
regulation of metal ion transportGO:001095940.022
establishment of protein localization to organelleGO:007259440.022
cellular response to external stimulusGO:007149620.022
positive regulation of ras protein signal transductionGO:004657910.021
cellular carbohydrate metabolic processGO:004426240.021
digestive system developmentGO:00551232890.021
negative regulation of protein phosphorylationGO:000193340.021
heart developmentGO:00075073130.021
ameboidal type cell migrationGO:00016671430.021
gtp catabolic processGO:000618420.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of calcium ion transportGO:005192420.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
guanosine containing compound catabolic processGO:190106920.020
stem cell differentiationGO:00488631170.020
single organism behaviorGO:0044708240.020
cortical actin cytoskeleton organizationGO:003086610.020
stem cell divisionGO:001714510.020
response to vitaminGO:003327330.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
posttranscriptional regulation of gene expressionGO:0010608140.020
sensory organ developmentGO:00074233930.020
cell matrix adhesionGO:000716040.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
regulation of developmental processGO:00507932470.020
gene silencingGO:001645840.019
muscle tissue developmentGO:00605371100.019
neuron neuron synaptic transmissionGO:000727010.019
regulation of cellular ketone metabolic processGO:001056570.019
cortical cytoskeleton organizationGO:003086510.019
cranial nerve developmentGO:0021545420.019
establishment of localization in cellGO:0051649770.019
somatic muscle developmentGO:000752540.019
striated muscle cell developmentGO:00550021080.019
digestive tract developmentGO:00485652650.019
gtp metabolic processGO:004603940.018
compound eye developmentGO:004874920.018
cell agingGO:000756920.018
central nervous system developmentGO:00074173870.018
regulation of protein ubiquitinationGO:003139630.018
adherens junction assemblyGO:003433310.018
protein targeting to nucleusGO:004474430.018
photoreceptor cell outer segment organizationGO:003584590.018
ribonucleoprotein complex biogenesisGO:0022613130.018
regulation of cellular amino acid metabolic processGO:000652100.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
cellular ketone metabolic processGO:0042180110.018
regulation of transmembrane transporter activityGO:002289820.018
single organism nuclear importGO:190259330.018
ribosomal small subunit biogenesisGO:004227420.018
apical junction assemblyGO:004329710.018
ribonucleoprotein complex subunit organizationGO:007182680.018
organic cyclic compound biosynthetic processGO:19013622230.018
zinc ion homeostasisGO:005506910.017
neuron differentiationGO:00301823530.017
negative regulation of biosynthetic processGO:0009890550.017
myotube cell developmentGO:0014904350.017
superoxide metabolic processGO:000680120.017
lipid metabolic processGO:0006629520.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
mrna metabolic processGO:0016071200.017
negative regulation of cellular catabolic processGO:003133030.017
regulation of growth rateGO:004000910.017
negative regulation of cellular processGO:00485232830.017
muscle fiber developmentGO:0048747520.017
ph reductionGO:004585110.017
regulation of system processGO:0044057400.017
negative regulation of ras protein signal transductionGO:004658010.017
muscle organ developmentGO:00075171010.017
zinc ion transmembrane transportGO:007157710.017
regulation of phGO:000688530.017
ras protein signal transductionGO:000726570.016
response to glucocorticoidGO:005138410.016
positive regulation of dna metabolic processGO:005105410.016
cellular amino acid metabolic processGO:000652070.016
regulation of cellular biosynthetic processGO:00313262450.016
fatty acid transportGO:001590810.016
adherens junction organizationGO:003433240.016
regulation of intracellular protein transportGO:003315730.016
regulation of protein catabolic processGO:004217610.016
macromolecule biosynthetic processGO:00090592270.016
regulation of transporter activityGO:003240920.016
lipid storageGO:001991510.016
i kappab kinase nf kappab signalingGO:000724940.016
positive regulation of cytoskeleton organizationGO:005149530.016
negative regulation of metabolic processGO:0009892860.016
regulation of rna metabolic processGO:00512522240.016
determination of heart left right asymmetryGO:00613711170.016
heart contractionGO:0060047710.016
single organism membrane fusionGO:004480120.016
g1 s transition of mitotic cell cycleGO:000008210.016
organelle organizationGO:00069962270.016
positive regulation of secretionGO:005104710.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
organic cyclic compound catabolic processGO:1901361150.016
regulation of intracellular signal transductionGO:1902531570.016
somitogenesisGO:0001756870.015
negative regulation of protein kinase activityGO:000646940.015
sodium ion importGO:009736930.015
forebrain cell migrationGO:002188510.015
negative regulation of autophagyGO:001050710.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
positive regulation of biological processGO:00485182530.015
extrinsic apoptotic signaling pathwayGO:009719130.015
gastrulationGO:00073692080.015
nucleobase containing compound transportGO:001593120.015
meiosis iGO:000712710.015
peptidyl serine phosphorylationGO:001810510.015
regulation of primary metabolic processGO:00800903110.015
regulation of nucleotide catabolic processGO:003081120.015
deathGO:00162651210.015
regulation of gtpase activityGO:004308720.015
regulation of nucleoside metabolic processGO:000911820.015
fertilizationGO:000956630.014
regulation of mrna processingGO:005068430.014
digestive tract morphogenesisGO:00485462310.014
actin filament based movementGO:003004810.014
carboxylic acid metabolic processGO:0019752220.014
regulation of dna replicationGO:000627530.014
regulation of developmental growthGO:0048638380.014
positive regulation of protein kinase b signalingGO:005189710.014
negative regulation of biological processGO:00485193040.014
cellular nitrogen compound catabolic processGO:0044270150.014
stem cell proliferationGO:007208940.014
regulation of purine nucleotide catabolic processGO:003312120.014
regulation of carbohydrate metabolic processGO:000610940.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
regulation of protein import into nucleusGO:004230620.014
mitochondrion organizationGO:000700540.014
anterior posterior pattern specificationGO:00099521520.014
b cell activationGO:004211320.014
regulation of signal transductionGO:00099662250.014
immune system developmentGO:00025201910.014
meiotic cell cycle processGO:190304630.014
lateral line system developmentGO:0048925760.014
regulation of epithelial cell proliferationGO:005067830.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
regulation of dna templated transcription in response to stressGO:004362000.014
gene silencing by rnaGO:003104740.014
determination of bilateral symmetryGO:00098552040.014
divalent inorganic cation homeostasisGO:0072507220.013
positive regulation of catabolic processGO:000989640.013
regulation of protein localization to nucleusGO:190018020.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
erk1 and erk2 cascadeGO:007037140.013
response to transition metal nanoparticleGO:1990267280.013
regulation of cellular phGO:003064110.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
response to uvGO:000941130.013
protein modification processGO:00362111000.013
meiotic nuclear divisionGO:000712640.013
oxoacid metabolic processGO:0043436310.013
vacuolar transportGO:000703420.013
positive regulation of multicellular organismal processGO:0051240520.013
regulation of multicellular organismal processGO:00512392770.013
zinc ion transportGO:000682920.013
sensory system developmentGO:0048880760.013
protein polymerizationGO:005125840.013
water homeostasisGO:003010440.013
cellular localizationGO:0051641970.013
cellular potassium ion transportGO:0071804100.013
positive regulation of cellular catabolic processGO:003133130.013
cellular response to xenobiotic stimulusGO:0071466350.013
tube morphogenesisGO:00352393490.013
negative regulation of cellular metabolic processGO:0031324770.013
ribonucleoprotein complex assemblyGO:002261850.013
cellular response to light stimulusGO:007148240.013
neurological system processGO:0050877620.013
regulation of bindingGO:005109830.013
establishment of rna localizationGO:005123630.013
regulation of cell differentiationGO:00455951420.012
cellular response to oxygen levelsGO:007145310.012
regulation of gtp catabolic processGO:003312420.012
rna localizationGO:000640340.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of dendrite developmentGO:005077330.012
regulation of transmembrane transportGO:0034762180.012
regulation of synapse organizationGO:005080730.012
cellular response to nitrogen compoundGO:190169960.012
nitric oxide metabolic processGO:004620920.012
gamete generationGO:0007276330.012
production of small rna involved in gene silencing by rnaGO:007091810.012
organelle fusionGO:004828430.012
protein import into nucleusGO:000660630.012
membrane fusionGO:006102520.012
specification of symmetryGO:00097992040.012
post embryonic organ developmentGO:004856940.012
somite developmentGO:0061053960.012
regulation of biosynthetic processGO:00098892500.012
cellular aldehyde metabolic processGO:000608140.012
protein complex localizationGO:003150310.012
biosynthetic processGO:00090582940.012
nuclear exportGO:005116810.012
negative regulation of epithelial cell proliferationGO:005068010.012
regulation of nucleocytoplasmic transportGO:004682220.012
cell part morphogenesisGO:00329902460.012
aromatic compound catabolic processGO:0019439150.012
regulation of localizationGO:00328791040.012
centrosome duplicationGO:005129810.012
regulation of cell activationGO:005086510.012
blastoderm segmentationGO:000735060.012
response to external stimulusGO:00096052640.012
xenobiotic metabolic processGO:000680540.012
intracellular signal transductionGO:0035556850.012
regulation of macromolecule biosynthetic processGO:00105562250.012
camera type eye developmentGO:00430102220.012
mitochondrion morphogenesisGO:007058420.012
negative regulation of cytokine mediated signaling pathwayGO:000196020.011
immune system processGO:00023762410.011
regulation of translational initiationGO:000644610.011
centrosome cycleGO:000709810.011
cell projection morphogenesisGO:00488582440.011
secondary metabolic processGO:001974830.011
androgen metabolic processGO:000820920.011
swimming behaviorGO:003626980.011
organic acid metabolic processGO:0006082310.011
phagocytosis engulfmentGO:000691110.011
regulation of signalingGO:00230512350.011
regulation of dendrite morphogenesisGO:004881430.011
single fertilizationGO:000733830.011
response to corticosteroidGO:003196010.011
sensory organ morphogenesisGO:00905962000.011
regulation of intracellular phGO:005145310.011
cell morphogenesis involved in differentiationGO:00009041950.011
gas transportGO:001566930.011
chromosome organization involved in meiosisGO:007019210.011
protein acetylationGO:000647320.011
cell cycle g1 s phase transitionGO:004484310.011
response to ketoneGO:190165410.011
organonitrogen compound metabolic processGO:1901564740.011
negative regulation of signalingGO:0023057960.011
rna 3 end processingGO:003112320.011
stem cell fate commitmentGO:004886510.011
female germ line stem cell maintenanceGO:003609910.011
regulation of ion transmembrane transporter activityGO:003241220.011
cell motilityGO:00488702440.011
positive regulation of secretion by cellGO:190353210.011
regulation of erk1 and erk2 cascadeGO:007037240.011
macromolecule modificationGO:00434121110.011
cellular component movementGO:00069283350.011
regulation of reactive oxygen species metabolic processGO:200037720.011
heart morphogenesisGO:00030071560.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of protein bindingGO:004339330.011
hindbrain formationGO:002157630.011
endosomal transportGO:001619720.011
exocytosisGO:000688710.011
transmembrane transportGO:00550851200.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
nucleic acid phosphodiester bond hydrolysisGO:009030560.011
regulation of blood vessel sizeGO:005088020.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
response to organic substanceGO:00100331530.011
nucleic acid transportGO:005065720.010
growthGO:00400071740.010
positive regulation of neuron deathGO:190121610.010
negative regulation of dna metabolic processGO:005105340.010
alpha amino acid metabolic processGO:190160530.010
development of primary female sexual characteristicsGO:004654540.010
spermatid differentiationGO:004851520.010
membrane invaginationGO:001032410.010
estrogen metabolic processGO:000821020.010
production of mirnas involved in gene silencing by mirnaGO:003519610.010
cellular response to decreased oxygen levelsGO:003629410.010
sarcomere organizationGO:0045214260.010
epithelial tube morphogenesisGO:00605621480.010
startle responseGO:000196440.010
positive regulation of cell activationGO:005086710.010
fat soluble vitamin metabolic processGO:000677540.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
cellular component maintenanceGO:004395430.010
actin cytoskeleton organizationGO:0030036630.010
rho protein signal transductionGO:000726650.010
inorganic ion transmembrane transportGO:0098660570.010

eif2c4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
muscular diseaseDOID:008000000.023
muscle tissue diseaseDOID:6600.023
myopathyDOID:42300.023
musculoskeletal system diseaseDOID:1700.023
bone marrow diseaseDOID:496100.022
immune system diseaseDOID:291400.022
hematopoietic system diseaseDOID:7400.022
anemiaDOID:235500.020
aplastic anemiaDOID:1244900.020
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
connective tissue diseaseDOID:6500.015
nervous system diseaseDOID:86300.015
organ system cancerDOID:005068600.014
bone diseaseDOID:008000100.013