Danio rerio

17 known processes

egf

epidermal growth factor

egf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external stimulusGO:00096052640.115
signal transductionGO:00071654550.093
Mouse Rat
ion transmembrane transportGO:0034220910.091
anion transmembrane transportGO:0098656120.089
response to mechanical stimulusGO:0009612240.077
chloride transmembrane transportGO:190247640.076
regulation of biological qualityGO:00650082630.073
regulation of multicellular organism growthGO:004001440.068
multicellular organism growthGO:003526440.061
cell surface receptor signaling pathwayGO:00071663250.057
Mouse Rat
larval developmentGO:000216420.055
inorganic anion transmembrane transportGO:0098661100.055
central nervous system developmentGO:00074173870.054
Mouse
nucleocytoplasmic transportGO:000691340.047
Mouse
regionalizationGO:00030022740.045
monovalent inorganic cation transportGO:0015672420.043
cellular macromolecule metabolic processGO:00442603910.042
Mouse
glial cell migrationGO:000834730.042
cognitionGO:005089010.041
morphogenesis of an epitheliumGO:00020093330.040
Mouse
maintenance of locationGO:005123540.040
cellular response to external stimulusGO:007149620.039
hemopoiesisGO:00300971830.038
embryonic organ developmentGO:00485683810.038
gtp metabolic processGO:004603940.037
rna biosynthetic processGO:00327741810.037
regulation of nucleoside metabolic processGO:000911820.036
lipid storageGO:001991510.036
positive regulation of catabolic processGO:000989640.036
Mouse
nuclear importGO:005117030.035
Mouse
regulation of cellular amine metabolic processGO:003323800.035
agingGO:000756820.034
heterocycle biosynthetic processGO:00181302150.034
positive regulation of map kinase activityGO:004340630.033
Mouse
guanosine containing compound catabolic processGO:190106920.033
regulation of cellular metabolic processGO:00313233200.033
Mouse
regulation of protein transportGO:005122330.033
Rat
organic cyclic compound biosynthetic processGO:19013622230.032
enzyme linked receptor protein signaling pathwayGO:00071671060.032
Mouse Rat
cellular amine metabolic processGO:004410620.032
gtp catabolic processGO:000618420.031
cellular response to extracellular stimulusGO:003166820.031
regulation of tube sizeGO:003515020.031
regulation of purine nucleotide catabolic processGO:003312120.031
guanosine containing compound metabolic processGO:190106840.031
amine metabolic processGO:000930820.031
single organism metabolic processGO:00447102170.030
Mouse
positive regulation of transportGO:005105020.030
nitrogen compound metabolic processGO:00068073190.030
determination of bilateral symmetryGO:00098552040.030
positive regulation of cellular catabolic processGO:003133130.029
Mouse
regulation of signal transductionGO:00099662250.029
Mouse
chemosensory behaviorGO:000763510.029
somatic muscle developmentGO:000752540.029
stem cell maintenanceGO:001982740.029
stem cell proliferationGO:007208940.029
specification of symmetryGO:00097992040.029
sodium ion transportGO:0006814240.029
regulation of nitrogen compound metabolic processGO:00511712510.028
protein importGO:001703830.028
Mouse
regulation of cellular amino acid metabolic processGO:000652100.028
regulation of rna metabolic processGO:00512522240.028
cellular amino acid metabolic processGO:000652070.028
single organism localizationGO:19025782250.028
Mouse Rat
cation transmembrane transportGO:0098655650.027
biosynthetic processGO:00090582940.027
protein targeting to nucleusGO:004474430.027
Mouse
regulation of protein complex assemblyGO:004325430.027
regulation of cellular ketone metabolic processGO:001056570.026
reactive oxygen species biosynthetic processGO:190340910.026
regulation of signalingGO:00230512350.026
Mouse
homeostatic processGO:00425921420.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
fatty acid transportGO:001590810.026
cellular response to starvationGO:000926710.026
neuron developmentGO:00486662620.026
neuron neuron synaptic transmissionGO:000727010.025
monovalent inorganic anion homeostasisGO:005508360.025
sensory organ developmentGO:00074233930.025
regulation of inflammatory responseGO:005072720.025
regulation of reactive oxygen species metabolic processGO:200037720.025
nitric oxide biosynthetic processGO:000680920.025
regulation of macromolecule biosynthetic processGO:00105562250.025
cellular component biogenesisGO:00440851780.024
regulation of metabolic processGO:00192223590.024
Mouse
dorsal ventral pattern formationGO:00099531250.024
positive regulation of cellular component biogenesisGO:004408930.024
regulation of nucleotide catabolic processGO:003081120.024
germ line stem cell maintenanceGO:003071820.024
regulation of macromolecule metabolic processGO:00602553170.023
Mouse
positive regulation of immune effector processGO:000269930.023
cellular biosynthetic processGO:00442492860.023
inner ear developmentGO:00488391260.023
regulation of protein import into nucleusGO:004230620.023
immune system developmentGO:00025201910.023
brain developmentGO:00074202930.023
Mouse
response to glucocorticoidGO:005138410.022
tube morphogenesisGO:00352393490.022
Mouse
cellular ketone metabolic processGO:0042180110.022
aromatic compound biosynthetic processGO:00194382170.022
positive regulation of gtp catabolic processGO:003312610.022
chloride transportGO:000682180.022
positive regulation of purine nucleotide catabolic processGO:003312310.022
response to chemicalGO:00422213200.021
nucleobase containing compound metabolic processGO:00061392740.021
regulation of wound healingGO:006104120.021
regulation of response to nutrient levelsGO:003210710.021
small molecule metabolic processGO:0044281770.021
positive regulation of cell cycleGO:004578730.021
regulation of metal ion transportGO:001095940.021
positive regulation of nucleotide catabolic processGO:003081310.021
transmembrane transportGO:00550851200.021
single organism nuclear importGO:190259330.021
Mouse
angiogenesisGO:00015251580.021
regulation of gtp catabolic processGO:003312420.021
transcription dna templatedGO:00063511810.021
regulation of gtpase activityGO:004308720.021
cellular response to nutrient levelsGO:003166920.021
cell migrationGO:00164772370.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
inorganic anion transportGO:0015698250.021
multi organism processGO:00517041340.021
stem cell divisionGO:001714510.021
b cell activationGO:004211320.021
cellular component morphogenesisGO:00329893360.021
negative regulation of protein phosphorylationGO:000193340.021
head developmentGO:00603223030.021
Mouse
transportGO:00068102200.020
Mouse Rat
organic substance biosynthetic processGO:19015762890.020
response to amino acidGO:004320020.020
digestive system developmentGO:00551232890.020
cell motilityGO:00488702440.020
regulation of blood vessel sizeGO:005088020.020
regulation of autophagyGO:001050630.020
epithelial cell differentiationGO:00308551160.020
embryonic organ morphogenesisGO:00485622740.020
establishment of protein localization to organelleGO:007259440.020
Mouse
long chain fatty acid metabolic processGO:000167610.020
response to uvGO:000941130.020
cellular response to molecule of bacterial originGO:007121930.020
chloride ion homeostasisGO:005506410.019
generation of neuronsGO:00486993850.019
regulation of cytoplasmic transportGO:190364940.019
regulation of blood pressureGO:000821710.019
digestive tract morphogenesisGO:00485462310.019
regulation of gene expressionGO:00104682650.019
regulation of protein targetingGO:190353320.019
regulation of intracellular protein transportGO:003315730.019
positive regulation of gtpase activityGO:004354710.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
Mouse
spermatid developmentGO:000728620.019
regulation of response to extracellular stimulusGO:003210410.019
anion homeostasisGO:005508190.018
positive regulation of cellular amine metabolic processGO:003324000.018
development of primary female sexual characteristicsGO:004654540.018
rna metabolic processGO:00160702190.018
regulation of transporter activityGO:003240920.018
reactive nitrogen species metabolic processGO:200105700.018
gene expressionGO:00104672520.018
positive regulation of nucleoside metabolic processGO:004597910.018
regulation of rna biosynthetic processGO:20011412130.018
cell morphogenesisGO:00009022890.018
cellular response to lipopolysaccharideGO:007122230.018
regulation of developmental processGO:00507932470.018
Mouse
neuron differentiationGO:00301823530.018
determination of heart left right asymmetryGO:00613711170.018
inorganic ion transmembrane transportGO:0098660570.017
cytokinesisGO:000091030.017
localization of cellGO:00516742440.017
compound eye developmentGO:004874920.017
regulation of cytokine productionGO:000181730.017
cell projection organizationGO:00300302840.017
response to hexoseGO:000974630.017
heterocycle metabolic processGO:00464832900.017
response to corticosteroidGO:003196010.017
cellular response to organic substanceGO:00713101050.017
protein localization to plasma membraneGO:007265910.017
spermatid differentiationGO:004851520.017
carboxylic acid metabolic processGO:0019752220.017
regulation of sodium ion transportGO:000202820.017
regulation of epithelial cell proliferationGO:005067830.017
nucleic acid templated transcriptionGO:00976591810.017
oxoacid metabolic processGO:0043436310.016
regulation of cell activationGO:005086510.016
regulation of protein localization to nucleusGO:190018020.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
cellular nitrogen compound metabolic processGO:00346412900.016
stem cell fate commitmentGO:004886510.016
lipid homeostasisGO:005508830.016
ras protein signal transductionGO:000726570.016
regulation of ion transmembrane transporter activityGO:003241220.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
macromolecule biosynthetic processGO:00090592270.016
response to external biotic stimulusGO:0043207970.016
regulation of cell differentiationGO:00455951420.016
regulation of transcription dna templatedGO:00063552130.016
response to monosaccharideGO:003428430.016
posterior lateral line developmentGO:0048916380.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
rho protein signal transductionGO:000726650.016
nuclear transportGO:005116940.016
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.016
determination of left right symmetryGO:00073681790.016
regulation of bindingGO:005109830.016
Mouse
smooth muscle contractionGO:000693920.015
phagocytosis engulfmentGO:000691110.015
regulation of synaptic plasticityGO:004816710.015
regulation of cellular biosynthetic processGO:00313262450.015
nitric oxide metabolic processGO:004620920.015
response to glucoseGO:000974930.015
cellular macromolecule biosynthetic processGO:00346452240.015
negative regulation of macromolecule metabolic processGO:0010605760.015
female gonad developmentGO:000858540.015
epithelial tube morphogenesisGO:00605621480.015
Mouse
embryonic heart tube morphogenesisGO:00031431080.015
transcription from rna polymerase ii promoterGO:0006366800.015
regulation of growth rateGO:004000910.015
establishment of protein localization to plasma membraneGO:009000210.015
g protein coupled receptor signaling pathwayGO:0007186740.015
meiotic nuclear divisionGO:000712640.015
positive regulation of multicellular organismal processGO:0051240520.015
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.015
chemical homeostasisGO:0048878490.015
negative regulation of catabolic processGO:000989530.015
response to nutrientGO:000758430.015
response to stressGO:00069502630.014
regulation of transmembrane transporter activityGO:002289820.014
phagocytosisGO:000690930.014
chordate embryonic developmentGO:00430092710.014
lateral line system developmentGO:0048925760.014
regulation of multicellular organismal processGO:00512392770.014
Mouse
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
negative regulation of defense responseGO:003134820.014
single organism transportGO:00447652060.014
Mouse Rat
positive regulation of cytokine productionGO:000181920.014
hatchingGO:003518840.014
positive regulation of inflammatory responseGO:005072910.014
establishment of localizationGO:00512342440.014
Mouse Rat
protein secretionGO:000930610.014
Rat
positive regulation of blood circulationGO:190352420.014
small molecule catabolic processGO:004428230.014
cell projection morphogenesisGO:00488582440.014
positive regulation of cell activationGO:005086710.014
kidney developmentGO:0001822920.014
regulation of nucleocytoplasmic transportGO:004682220.014
response to ketoneGO:190165410.014
organism emergence from protective structureGO:007168440.014
embryonic heart tube developmentGO:00350501330.014
regulation of rho protein signal transductionGO:003502320.014
tissue remodelingGO:004877140.014
gastrulationGO:00073692080.014
negative regulation of cellular catabolic processGO:003133030.014
negative regulation of autophagyGO:001050710.014
periodic partitioningGO:000736510.014
long chain fatty acid transportGO:001590910.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
macroautophagyGO:001623610.014
peptide transportGO:001583310.014
cation transportGO:0006812810.014
response to carbohydrateGO:000974330.013
cell part morphogenesisGO:00329902460.013
immune system processGO:00023762410.013
regulation of phGO:000688530.013
calcium ion importGO:007050940.013
protein import into nucleusGO:000660630.013
Mouse
cellular response to endogenous stimulusGO:0071495680.013
mononuclear cell proliferationGO:003294310.013
positive regulation of wound healingGO:009030310.013
cellular carbohydrate metabolic processGO:004426240.013
intracellular signal transductionGO:0035556850.013
Mouse
alcohol biosynthetic processGO:004616520.013
response to abiotic stimulusGO:00096281220.013
heart loopingGO:0001947940.013
multicellular organismal macromolecule metabolic processGO:004425920.013
rna localizationGO:000640340.013
nucleic acid metabolic processGO:00903042440.013
regulation of establishment of protein localizationGO:007020140.013
Rat
metal ion transportGO:0030001580.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
regulation of erk1 and erk2 cascadeGO:007037240.013
organic cyclic compound metabolic processGO:19013603010.013
regulation of ras gtpase activityGO:003231820.013
synaptic growth at neuromuscular junctionGO:005112420.013
energy reserve metabolic processGO:000611220.013
female sex differentiationGO:004666040.013
digestive tract developmentGO:00485652650.013
segmentationGO:0035282970.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
regulation of carbohydrate metabolic processGO:000610940.013
superoxide metabolic processGO:000680120.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
Mouse
regulation of protein catabolic processGO:004217610.013
Mouse
inorganic cation transmembrane transportGO:0098662500.012
negative regulation of dna metabolic processGO:005105340.012
regulation of reproductive processGO:200024140.012
collagen metabolic processGO:003296320.012
b cell mediated immunityGO:001972430.012
regulation of dna replicationGO:000627530.012
positive regulation of leukocyte mediated immunityGO:000270510.012
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.012
regulation of protein ubiquitinationGO:003139630.012
Mouse
ammonium transmembrane transportGO:007248820.012
g1 s transition of mitotic cell cycleGO:000008210.012
erk1 and erk2 cascadeGO:007037140.012
regulation of biosynthetic processGO:00098892500.012
cellular component movementGO:00069283350.012
heart morphogenesisGO:00030071560.012
organonitrogen compound metabolic processGO:1901564740.012
regulation of photoreceptor cell differentiationGO:004653220.012
sodium ion transmembrane transportGO:0035725210.012
i kappab kinase nf kappab signalingGO:000724940.012
regulation of response to stimulusGO:00485832690.012
Mouse
phosphatidylinositol mediated signalingGO:004801520.012
bicarbonate transportGO:001570140.012
immunoglobulin mediated immune responseGO:001606430.012
anion transportGO:0006820380.012
urogenital system developmentGO:0001655970.012
ion transportGO:00068111140.012
cellular aromatic compound metabolic processGO:00067252950.012
locomotionGO:00400113130.012
adult behaviorGO:003053420.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
protein localization to nucleusGO:003450430.012
Mouse
positive regulation of response to stimulusGO:0048584800.012
Mouse
cellular component assemblyGO:00226071700.012
sex determinationGO:000753010.012
antimicrobial humoral responseGO:001973020.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
negative regulation of protein complex assemblyGO:003133310.012
stem cell differentiationGO:00488631170.012
positive regulation of dna metabolic processGO:005105410.012
autophagyGO:000691440.012
peptidyl lysine acetylationGO:001839420.012
regulation of dna recombinationGO:000001820.011
modification dependent protein catabolic processGO:001994130.011
Mouse
inositol lipid mediated signalingGO:004801720.011
cellular component disassemblyGO:002241110.011
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.011
response to alkaloidGO:004327920.011
somite developmentGO:0061053960.011
multicellular organismal metabolic processGO:004423620.011
meiotic cell cycle processGO:190304630.011
response to biotic stimulusGO:0009607970.011
regulation of cell developmentGO:00602841000.011
carbohydrate biosynthetic processGO:001605110.011
cell killingGO:000190620.011
positive regulation of epithelial cell proliferationGO:005067910.011
response to bacteriumGO:0009617580.011
negative regulation of protein transportGO:005122430.011
cell cycle g1 s phase transitionGO:004484310.011
small gtpase mediated signal transductionGO:000726480.011
production of molecular mediator of immune responseGO:000244020.011
protein metabolic processGO:00195381830.011
Mouse
negative regulation of metabolic processGO:0009892860.011
regulation of muscle contractionGO:000693730.011
lymphocyte proliferationGO:004665110.011
cranial nerve developmentGO:0021545420.011
synaptic transmission cholinergicGO:000727140.011
cell substrate junction assemblyGO:000704420.011
axon developmentGO:00615641660.011
lateral line developmentGO:0048882660.011
positive regulation of leukocyte mediated cytotoxicityGO:000191210.011
positive regulation of secretionGO:005104710.011
negative regulation of cysteine type endopeptidase activityGO:200011780.011
organic acid metabolic processGO:0006082310.011
response to vitaminGO:003327330.011
modulation by virus of host morphology or physiologyGO:001904810.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of lipase activityGO:006019120.011
forebrain cell migrationGO:002188510.011
cellular response to biotic stimulusGO:007121630.011
embryo development ending in birth or egg hatchingGO:00097922710.011
fat soluble vitamin metabolic processGO:000677540.010
cellular nitrogen compound biosynthetic processGO:00442712180.010
glucose homeostasisGO:004259310.010
adherens junction organizationGO:003433240.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
peptide metabolic processGO:000651810.010
ion homeostasisGO:0050801410.010
membrane repolarizationGO:008600920.010
cell fate commitmentGO:0045165990.010
protein complex disassemblyGO:004324110.010
ossificationGO:0001503230.010
regulation of cell deathGO:00109411030.010
protein polymerizationGO:005125840.010
mitochondrion organizationGO:000700540.010
complement activationGO:000695630.010
negative regulation of protein kinase activityGO:000646940.010
positive regulation of gliogenesisGO:001401520.010
internal protein amino acid acetylationGO:000647520.010
homeostasis of number of cellsGO:0048872620.010
protein acetylationGO:000647320.010
eye developmentGO:00016542770.010
modification dependent macromolecule catabolic processGO:004363230.010
Mouse
sensory perception of chemical stimulusGO:000760630.010

egf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.013
inherited metabolic disorderDOID:65500.012
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011