| sensory organ development | GO:0007423 | 393 | 0.620 | |
| cellular component biogenesis | GO:0044085 | 178 | 0.492 | |
| regulation of fatty acid metabolic process | GO:0019217 | 1 | 0.366 | |
| establishment of localization | GO:0051234 | 244 | 0.274 | Fly |
| neuron neuron synaptic transmission | GO:0007270 | 1 | 0.213 | |
| cellular component assembly | GO:0022607 | 170 | 0.197 | |
| regulation of membrane potential | GO:0042391 | 23 | 0.192 | |
| system process | GO:0003008 | 185 | 0.178 | |
| actin cytoskeleton organization | GO:0030036 | 63 | 0.163 | |
| central nervous system development | GO:0007417 | 387 | 0.160 | |
| head development | GO:0060322 | 303 | 0.154 | |
| response to vitamin b3 | GO:0033552 | 2 | 0.151 | |
| regulation of sarcomere organization | GO:0060297 | 2 | 0.140 | |
| macromolecular complex subunit organization | GO:0043933 | 74 | 0.131 | |
| single organism metabolic process | GO:0044710 | 217 | 0.129 | Yeast Mouse Fly |
| actin filament based process | GO:0030029 | 64 | 0.113 | |
| homeostatic process | GO:0042592 | 142 | 0.098 | |
| multicellular organismal signaling | GO:0035637 | 22 | 0.097 | |
| protein complex assembly | GO:0006461 | 30 | 0.095 | |
| lipid storage | GO:0019915 | 1 | 0.092 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 2 | 0.088 | |
| neurological system process | GO:0050877 | 62 | 0.087 | |
| maintenance of location | GO:0051235 | 4 | 0.085 | |
| protein metabolic process | GO:0019538 | 183 | 0.078 | |
| regulation of synapse organization | GO:0050807 | 3 | 0.077 | |
| cell matrix adhesion | GO:0007160 | 4 | 0.075 | |
| brain development | GO:0007420 | 293 | 0.075 | |
| regionalization | GO:0003002 | 274 | 0.075 | |
| epithelial cell differentiation | GO:0030855 | 116 | 0.070 | |
| transport | GO:0006810 | 220 | 0.069 | Fly |
| phagocytosis | GO:0006909 | 3 | 0.069 | |
| positive regulation of transport | GO:0051050 | 2 | 0.068 | |
| organonitrogen compound metabolic process | GO:1901564 | 74 | 0.068 | |
| negative regulation of cellular metabolic process | GO:0031324 | 77 | 0.065 | |
| response to oxygen containing compound | GO:1901700 | 55 | 0.062 | |
| aging | GO:0007568 | 2 | 0.061 | |
| hydrogen peroxide metabolic process | GO:0042743 | 2 | 0.059 | |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.059 | |
| regulation of biological quality | GO:0065008 | 263 | 0.058 | |
| single organism transport | GO:0044765 | 206 | 0.057 | Fly |
| response to hormone | GO:0009725 | 48 | 0.056 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 8 | 0.055 | |
| striated muscle cell development | GO:0055002 | 108 | 0.054 | |
| urogenital system development | GO:0001655 | 97 | 0.054 | |
| acylglycerol homeostasis | GO:0055090 | 2 | 0.054 | |
| macromolecule modification | GO:0043412 | 111 | 0.052 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 2 | 0.052 | |
| adult behavior | GO:0030534 | 2 | 0.051 | |
| cation transmembrane transport | GO:0098655 | 65 | 0.051 | |
| actin filament organization | GO:0007015 | 15 | 0.049 | |
| regulation of inflammatory response | GO:0050727 | 2 | 0.048 | |
| negative regulation of protein kinase activity | GO:0006469 | 4 | 0.047 | |
| organelle organization | GO:0006996 | 227 | 0.047 | Fly |
| cellular macromolecular complex assembly | GO:0034622 | 24 | 0.046 | |
| cellular response to chemical stimulus | GO:0070887 | 157 | 0.044 | |
| response to oxidative stress | GO:0006979 | 11 | 0.044 | |
| response to organic substance | GO:0010033 | 153 | 0.043 | |
| positive regulation of lipid metabolic process | GO:0045834 | 1 | 0.043 | |
| regulation of synapse assembly | GO:0051963 | 3 | 0.043 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 7 | 0.042 | |
| negative regulation of protein phosphorylation | GO:0001933 | 4 | 0.042 | |
| histone h3 k4 methylation | GO:0051568 | 2 | 0.042 | |
| cellular carbohydrate metabolic process | GO:0044262 | 4 | 0.041 | |
| cell substrate adhesion | GO:0031589 | 4 | 0.040 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 107 | 0.040 | Mouse |
| regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902175 | 2 | 0.040 | |
| transmission of nerve impulse | GO:0019226 | 19 | 0.040 | |
| cytoskeleton organization | GO:0007010 | 96 | 0.040 | |
| cellular response to endogenous stimulus | GO:0071495 | 68 | 0.039 | |
| neuronal action potential | GO:0019228 | 18 | 0.039 | |
| glial cell proliferation | GO:0014009 | 4 | 0.039 | |
| sarcomere organization | GO:0045214 | 26 | 0.038 | |
| actomyosin structure organization | GO:0031032 | 53 | 0.037 | |
| cellular component morphogenesis | GO:0032989 | 336 | 0.037 | Mouse |
| protein complex subunit organization | GO:0071822 | 46 | 0.036 | |
| single organism localization | GO:1902578 | 225 | 0.036 | Fly |
| protein modification process | GO:0036211 | 100 | 0.035 | |
| regulation of cell communication | GO:0010646 | 232 | 0.035 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 2 | 0.034 | |
| skeletal muscle organ development | GO:0060538 | 78 | 0.034 | |
| response to oxygen levels | GO:0070482 | 25 | 0.034 | |
| cell substrate adherens junction assembly | GO:0007045 | 1 | 0.034 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 4 | 0.034 | |
| regulation of organelle assembly | GO:1902115 | 4 | 0.033 | |
| regulation of rna biosynthetic process | GO:2001141 | 213 | 0.033 | |
| macromolecular complex assembly | GO:0065003 | 35 | 0.032 | |
| response to nutrient | GO:0007584 | 3 | 0.031 | |
| cellular ketone metabolic process | GO:0042180 | 11 | 0.031 | |
| cellular aromatic compound metabolic process | GO:0006725 | 295 | 0.031 | |
| regulation of dendrite development | GO:0050773 | 3 | 0.030 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 3 | 0.029 | |
| regulation of epithelial cell proliferation | GO:0050678 | 3 | 0.029 | |
| lipid metabolic process | GO:0006629 | 52 | 0.029 | Yeast Mouse Fly |
| regulation of heart growth | GO:0060420 | 2 | 0.029 | |
| peptide metabolic process | GO:0006518 | 1 | 0.029 | |
| protein homooligomerization | GO:0051260 | 3 | 0.029 | |
| regulation of synaptic plasticity | GO:0048167 | 1 | 0.028 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 4 | 0.028 | |
| regulation of signaling | GO:0023051 | 235 | 0.028 | |
| cell death in response to oxidative stress | GO:0036473 | 2 | 0.028 | |
| organic substance biosynthetic process | GO:1901576 | 289 | 0.028 | |
| response to biotic stimulus | GO:0009607 | 97 | 0.028 | |
| growth | GO:0040007 | 174 | 0.027 | |
| cellular response to oxygen containing compound | GO:1901701 | 20 | 0.027 | |
| neuromuscular synaptic transmission | GO:0007274 | 2 | 0.026 | |
| eye development | GO:0001654 | 277 | 0.026 | |
| cellular lipid metabolic process | GO:0044255 | 36 | 0.025 | Yeast Mouse Fly |
| cartilage morphogenesis | GO:0060536 | 13 | 0.025 | |
| digestive system process | GO:0022600 | 9 | 0.025 | |
| negative regulation of defense response | GO:0031348 | 2 | 0.025 | |
| response to stress | GO:0006950 | 263 | 0.024 | Fly |
| protein secretion | GO:0009306 | 1 | 0.024 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 4 | 0.024 | |
| brain morphogenesis | GO:0048854 | 18 | 0.024 | |
| regulation of cellular component organization | GO:0051128 | 86 | 0.024 | |
| positive regulation of glucose transport | GO:0010828 | 1 | 0.024 | |
| calcium ion transport into cytosol | GO:0060402 | 3 | 0.023 | |
| negative regulation of cellular process | GO:0048523 | 283 | 0.023 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.023 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 3 | 0.022 | |
| negative regulation of kinase activity | GO:0033673 | 4 | 0.022 | |
| neurotransmitter secretion | GO:0007269 | 2 | 0.022 | |
| carbohydrate homeostasis | GO:0033500 | 1 | 0.021 | |
| regulation of lipase activity | GO:0060191 | 2 | 0.021 | |
| rna metabolic process | GO:0016070 | 219 | 0.021 | |
| regulation of postsynaptic membrane potential | GO:0060078 | 1 | 0.021 | |
| lipid oxidation | GO:0034440 | 1 | 0.020 | |
| cardiac muscle cell development | GO:0055013 | 20 | 0.020 | |
| chordate embryonic development | GO:0043009 | 271 | 0.020 | |
| cell proliferation | GO:0008283 | 80 | 0.020 | |
| multicellular organism growth | GO:0035264 | 4 | 0.020 | |
| negative regulation of response to stimulus | GO:0048585 | 104 | 0.020 | |
| carboxylic acid metabolic process | GO:0019752 | 22 | 0.020 | |
| cellular protein modification process | GO:0006464 | 100 | 0.020 | |
| antimicrobial humoral response | GO:0019730 | 2 | 0.019 | |
| protein complex biogenesis | GO:0070271 | 30 | 0.019 | |
| neurotransmitter transport | GO:0006836 | 2 | 0.019 | |
| cellular biogenic amine metabolic process | GO:0006576 | 2 | 0.019 | |
| regulation of cell matrix adhesion | GO:0001952 | 1 | 0.019 | |
| glucose homeostasis | GO:0042593 | 1 | 0.019 | |
| organelle fusion | GO:0048284 | 3 | 0.019 | Fly |
| small molecule metabolic process | GO:0044281 | 77 | 0.019 | |
| muscle organ development | GO:0007517 | 101 | 0.019 | |
| biosynthetic process | GO:0009058 | 294 | 0.018 | |
| cell migration | GO:0016477 | 237 | 0.018 | |
| response to amino acid | GO:0043200 | 2 | 0.018 | |
| regulation of neurotransmitter transport | GO:0051588 | 1 | 0.018 | |
| regulation of ph | GO:0006885 | 3 | 0.018 | |
| regulation of metabolic process | GO:0019222 | 359 | 0.018 | |
| regulation of transcription dna templated | GO:0006355 | 213 | 0.018 | |
| oxoacid metabolic process | GO:0043436 | 31 | 0.018 | |
| response to ketone | GO:1901654 | 1 | 0.018 | |
| response to chemical | GO:0042221 | 320 | 0.018 | |
| single organism organelle organization | GO:1902589 | 199 | 0.018 | Fly |
| adherens junction organization | GO:0034332 | 4 | 0.018 | |
| regulation of receptor activity | GO:0010469 | 2 | 0.017 | |
| myelination | GO:0042552 | 18 | 0.017 | Mouse |
| regulation of multicellular organismal process | GO:0051239 | 277 | 0.017 | |
| negative regulation of secretion by cell | GO:1903531 | 2 | 0.017 | |
| adherens junction assembly | GO:0034333 | 1 | 0.017 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 4 | 0.017 | |
| regulation of cellular biosynthetic process | GO:0031326 | 245 | 0.017 | |
| regulation of developmental process | GO:0050793 | 247 | 0.017 | |
| locomotory behavior | GO:0007626 | 34 | 0.017 | |
| regulation of cell death | GO:0010941 | 103 | 0.017 | |
| guanosine containing compound metabolic process | GO:1901068 | 4 | 0.017 | |
| synapsis | GO:0007129 | 1 | 0.017 | |
| regulation of protein complex assembly | GO:0043254 | 3 | 0.017 | |
| cellular response to biotic stimulus | GO:0071216 | 3 | 0.017 | |
| chemical homeostasis | GO:0048878 | 49 | 0.017 | |
| cell substrate junction assembly | GO:0007044 | 2 | 0.016 | |
| ion transmembrane transport | GO:0034220 | 91 | 0.016 | |
| cellular nitrogen compound metabolic process | GO:0034641 | 290 | 0.016 | |
| small molecule catabolic process | GO:0044282 | 3 | 0.016 | |
| regulation of cellular component biogenesis | GO:0044087 | 12 | 0.016 | |
| neuron development | GO:0048666 | 262 | 0.016 | |
| regulation of rac protein signal transduction | GO:0035020 | 1 | 0.016 | |
| cellular nitrogen compound biosynthetic process | GO:0044271 | 218 | 0.016 | |
| nucleobase containing compound metabolic process | GO:0006139 | 274 | 0.016 | |
| regulation of filopodium assembly | GO:0051489 | 2 | 0.016 | |
| negative regulation of reproductive process | GO:2000242 | 3 | 0.016 | |
| dna biosynthetic process | GO:0071897 | 3 | 0.016 | |
| protein dephosphorylation | GO:0006470 | 3 | 0.016 | |
| regulation of cell shape | GO:0008360 | 1 | 0.016 | |
| skeletal muscle thin filament assembly | GO:0030240 | 4 | 0.015 | |
| centrosome localization | GO:0051642 | 1 | 0.015 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 1 | 0.015 | |
| pigmentation | GO:0043473 | 85 | 0.015 | |
| membrane fusion | GO:0061025 | 2 | 0.015 | Fly |
| cell projection organization | GO:0030030 | 284 | 0.015 | |
| protein localization to plasma membrane | GO:0072659 | 1 | 0.015 | |
| regulation of reproductive process | GO:2000241 | 4 | 0.015 | |
| cellular response to decreased oxygen levels | GO:0036294 | 1 | 0.015 | |
| positive regulation of muscle cell differentiation | GO:0051149 | 1 | 0.015 | |
| striated muscle tissue development | GO:0014706 | 110 | 0.015 | |
| chromosome organization | GO:0051276 | 31 | 0.015 | |
| apical junction assembly | GO:0043297 | 1 | 0.015 | |
| regulation of establishment of protein localization | GO:0070201 | 4 | 0.015 | |
| negative regulation of biological process | GO:0048519 | 304 | 0.015 | |
| regulation of transmembrane transporter activity | GO:0022898 | 2 | 0.015 | |
| organic acid metabolic process | GO:0006082 | 31 | 0.015 | |
| muscle tissue development | GO:0060537 | 110 | 0.015 | |
| positive regulation of striated muscle cell differentiation | GO:0051155 | 1 | 0.015 | |
| response to nitrogen compound | GO:1901698 | 19 | 0.015 | |
| heterocycle metabolic process | GO:0046483 | 290 | 0.015 | |
| amine metabolic process | GO:0009308 | 2 | 0.014 | |
| multi organism process | GO:0051704 | 134 | 0.014 | |
| negative regulation of mapk cascade | GO:0043409 | 4 | 0.014 | |
| organism emergence from protective structure | GO:0071684 | 4 | 0.014 | |
| peptidyl serine phosphorylation | GO:0018105 | 1 | 0.014 | |
| intracellular signal transduction | GO:0035556 | 85 | 0.014 | Mouse |
| regulation of signal transduction | GO:0009966 | 225 | 0.014 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.014 | |
| regulation of protein transport | GO:0051223 | 3 | 0.014 | |
| glycerolipid biosynthetic process | GO:0045017 | 1 | 0.014 | |
| fertilization | GO:0009566 | 3 | 0.014 | |
| cellular response to hypoxia | GO:0071456 | 1 | 0.014 | |
| water homeostasis | GO:0030104 | 4 | 0.013 | |
| rna localization | GO:0006403 | 4 | 0.013 | |
| inflammatory response | GO:0006954 | 8 | 0.013 | |
| regulation of cell activation | GO:0050865 | 1 | 0.013 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 76 | 0.013 | |
| response to bacterium | GO:0009617 | 58 | 0.013 | |
| cellular response to oxygen levels | GO:0071453 | 1 | 0.013 | |
| schwann cell development | GO:0014044 | 9 | 0.013 | |
| nitrogen compound metabolic process | GO:0006807 | 319 | 0.013 | |
| regulation of phosphate metabolic process | GO:0019220 | 43 | 0.013 | |
| peptidyl lysine methylation | GO:0018022 | 3 | 0.013 | |
| osteoclast differentiation | GO:0030316 | 1 | 0.013 | |
| synaptic vesicle transport | GO:0048489 | 1 | 0.013 | |
| stem cell division | GO:0017145 | 1 | 0.013 | |
| inorganic cation transmembrane transport | GO:0098662 | 50 | 0.013 | |
| gtp catabolic process | GO:0006184 | 2 | 0.012 | |
| regulation of stem cell proliferation | GO:0072091 | 2 | 0.012 | |
| negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902176 | 2 | 0.012 | |
| response to radiation | GO:0009314 | 51 | 0.012 | |
| cell junction organization | GO:0034330 | 11 | 0.012 | |
| cellular response to organic substance | GO:0071310 | 105 | 0.012 | |
| phagocytosis engulfment | GO:0006911 | 1 | 0.012 | |
| programmed cell death | GO:0012501 | 119 | 0.012 | |
| skeletal myofibril assembly | GO:0014866 | 7 | 0.012 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 4 | 0.012 | |
| fatty acid oxidation | GO:0019395 | 1 | 0.012 | |
| exocytosis | GO:0006887 | 1 | 0.012 | |
| kidney development | GO:0001822 | 92 | 0.012 | |
| positive regulation of cell communication | GO:0010647 | 56 | 0.012 | |
| cellular component disassembly | GO:0022411 | 1 | 0.012 | |
| membrane invagination | GO:0010324 | 1 | 0.011 | |
| phosphate containing compound metabolic process | GO:0006796 | 108 | 0.011 | Yeast Mouse Fly |
| response to hypoxia | GO:0001666 | 25 | 0.011 | |
| regulation of rho protein signal transduction | GO:0035023 | 2 | 0.011 | |
| cellular protein complex assembly | GO:0043623 | 19 | 0.011 | |
| regulation of multicellular organism growth | GO:0040014 | 4 | 0.011 | |
| inorganic ion transmembrane transport | GO:0098660 | 57 | 0.011 | |
| regulation of mitochondrion organization | GO:0010821 | 1 | 0.011 | |
| regulation of response to oxidative stress | GO:1902882 | 2 | 0.011 | |
| determination of left right symmetry | GO:0007368 | 179 | 0.011 | |
| regulation of circadian rhythm | GO:0042752 | 4 | 0.011 | |
| centrosome organization | GO:0051297 | 1 | 0.011 | |
| cell death | GO:0008219 | 121 | 0.011 | |
| protein polyubiquitination | GO:0000209 | 4 | 0.011 | |
| protein localization to cell surface | GO:0034394 | 3 | 0.011 | |
| organic substance transport | GO:0071702 | 58 | 0.011 | |
| death | GO:0016265 | 121 | 0.011 | |
| response to endogenous stimulus | GO:0009719 | 83 | 0.011 | |
| muscle system process | GO:0003012 | 20 | 0.011 | |
| hormone secretion | GO:0046879 | 2 | 0.011 | |
| meiotic cell cycle process | GO:1903046 | 3 | 0.011 | |
| muscle structure development | GO:0061061 | 196 | 0.011 | |
| renal system development | GO:0072001 | 94 | 0.011 | |
| regulation of skeletal muscle fiber development | GO:0048742 | 2 | 0.011 | |
| nucleic acid metabolic process | GO:0090304 | 244 | 0.011 | |
| regulation of apoptotic process | GO:0042981 | 98 | 0.011 | |
| pigment granule organization | GO:0048753 | 4 | 0.011 | |
| cell motility | GO:0048870 | 244 | 0.011 | |
| response to corticosteroid | GO:0031960 | 1 | 0.011 | |
| regulation of cell substrate adhesion | GO:0010810 | 1 | 0.010 | |
| cellular macromolecule biosynthetic process | GO:0034645 | 224 | 0.010 | |
| cellular protein catabolic process | GO:0044257 | 4 | 0.010 | |
| positive regulation of epithelial cell proliferation | GO:0050679 | 1 | 0.010 | |
| negative regulation of multi organism process | GO:0043901 | 3 | 0.010 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 1 | 0.010 | |
| cytosolic calcium ion transport | GO:0060401 | 3 | 0.010 | |
| protein acetylation | GO:0006473 | 2 | 0.010 | |
| aorta development | GO:0035904 | 4 | 0.010 | |
| histone lysine demethylation | GO:0070076 | 2 | 0.010 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 3 | 0.010 | |
| regulation of cytoplasmic transport | GO:1903649 | 4 | 0.010 | |
| negative regulation of gene expression | GO:0010629 | 65 | 0.010 | |
| positive regulation of immune effector process | GO:0002699 | 3 | 0.010 | |
| regulation of nitrogen compound metabolic process | GO:0051171 | 251 | 0.010 | |
| response to decreased oxygen levels | GO:0036293 | 25 | 0.010 | |
| cardiac muscle myosin thick filament assembly | GO:0071690 | 1 | 0.010 | |