Danio rerio

0 known processes

pikfyve

phosphoinositide kinase, FYVE finger containing

(Aliases: pip5k3,wu:fo93c03)

pikfyve biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.620
cellular component biogenesisGO:00440851780.492
regulation of fatty acid metabolic processGO:001921710.366
establishment of localizationGO:00512342440.274
Fly
neuron neuron synaptic transmissionGO:000727010.213
cellular component assemblyGO:00226071700.197
regulation of membrane potentialGO:0042391230.192
system processGO:00030081850.178
actin cytoskeleton organizationGO:0030036630.163
central nervous system developmentGO:00074173870.160
head developmentGO:00603223030.154
response to vitamin b3GO:003355220.151
regulation of sarcomere organizationGO:006029720.140
macromolecular complex subunit organizationGO:0043933740.131
single organism metabolic processGO:00447102170.129
Yeast Mouse Fly
actin filament based processGO:0030029640.113
homeostatic processGO:00425921420.098
multicellular organismal signalingGO:0035637220.097
protein complex assemblyGO:0006461300.095
lipid storageGO:001991510.092
regulation of cellular response to oxidative stressGO:190040720.088
neurological system processGO:0050877620.087
maintenance of locationGO:005123540.085
protein metabolic processGO:00195381830.078
regulation of synapse organizationGO:005080730.077
cell matrix adhesionGO:000716040.075
brain developmentGO:00074202930.075
regionalizationGO:00030022740.075
epithelial cell differentiationGO:00308551160.070
transportGO:00068102200.069
Fly
phagocytosisGO:000690930.069
positive regulation of transportGO:005105020.068
organonitrogen compound metabolic processGO:1901564740.068
negative regulation of cellular metabolic processGO:0031324770.065
response to oxygen containing compoundGO:1901700550.062
agingGO:000756820.061
hydrogen peroxide metabolic processGO:004274320.059
cellular macromolecule metabolic processGO:00442603910.059
regulation of biological qualityGO:00650082630.058
single organism transportGO:00447652060.057
Fly
response to hormoneGO:0009725480.056
regulation of actin cytoskeleton organizationGO:003295680.055
striated muscle cell developmentGO:00550021080.054
urogenital system developmentGO:0001655970.054
acylglycerol homeostasisGO:005509020.054
macromolecule modificationGO:00434121110.052
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.052
adult behaviorGO:003053420.051
cation transmembrane transportGO:0098655650.051
actin filament organizationGO:0007015150.049
regulation of inflammatory responseGO:005072720.048
negative regulation of protein kinase activityGO:000646940.047
organelle organizationGO:00069962270.047
Fly
cellular macromolecular complex assemblyGO:0034622240.046
cellular response to chemical stimulusGO:00708871570.044
response to oxidative stressGO:0006979110.044
response to organic substanceGO:00100331530.043
positive regulation of lipid metabolic processGO:004583410.043
regulation of synapse assemblyGO:005196330.043
regulation of cellular ketone metabolic processGO:001056570.042
negative regulation of protein phosphorylationGO:000193340.042
histone h3 k4 methylationGO:005156820.042
cellular carbohydrate metabolic processGO:004426240.041
cell substrate adhesionGO:003158940.040
cellular component assembly involved in morphogenesisGO:00109271070.040
Mouse
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.040
transmission of nerve impulseGO:0019226190.040
cytoskeleton organizationGO:0007010960.040
cellular response to endogenous stimulusGO:0071495680.039
neuronal action potentialGO:0019228180.039
glial cell proliferationGO:001400940.039
sarcomere organizationGO:0045214260.038
actomyosin structure organizationGO:0031032530.037
cellular component morphogenesisGO:00329893360.037
Mouse
protein complex subunit organizationGO:0071822460.036
single organism localizationGO:19025782250.036
Fly
protein modification processGO:00362111000.035
regulation of cell communicationGO:00106462320.035
regulation of oxidative stress induced cell deathGO:190320120.034
skeletal muscle organ developmentGO:0060538780.034
response to oxygen levelsGO:0070482250.034
cell substrate adherens junction assemblyGO:000704510.034
regulation of carbohydrate metabolic processGO:000610940.034
regulation of organelle assemblyGO:190211540.033
regulation of rna biosynthetic processGO:20011412130.033
macromolecular complex assemblyGO:0065003350.032
response to nutrientGO:000758430.031
cellular ketone metabolic processGO:0042180110.031
cellular aromatic compound metabolic processGO:00067252950.031
regulation of dendrite developmentGO:005077330.030
regulation of extrinsic apoptotic signaling pathwayGO:200123630.029
regulation of epithelial cell proliferationGO:005067830.029
lipid metabolic processGO:0006629520.029
Yeast Mouse Fly
regulation of heart growthGO:006042020.029
peptide metabolic processGO:000651810.029
protein homooligomerizationGO:005126030.029
regulation of synaptic plasticityGO:004816710.028
regulation of cellular carbohydrate metabolic processGO:001067540.028
regulation of signalingGO:00230512350.028
cell death in response to oxidative stressGO:003647320.028
organic substance biosynthetic processGO:19015762890.028
response to biotic stimulusGO:0009607970.028
growthGO:00400071740.027
cellular response to oxygen containing compoundGO:1901701200.027
neuromuscular synaptic transmissionGO:000727420.026
eye developmentGO:00016542770.026
cellular lipid metabolic processGO:0044255360.025
Yeast Mouse Fly
cartilage morphogenesisGO:0060536130.025
digestive system processGO:002260090.025
negative regulation of defense responseGO:003134820.025
response to stressGO:00069502630.024
Fly
protein secretionGO:000930610.024
i kappab kinase nf kappab signalingGO:000724940.024
brain morphogenesisGO:0048854180.024
regulation of cellular component organizationGO:0051128860.024
positive regulation of glucose transportGO:001082810.024
calcium ion transport into cytosolGO:006040230.023
negative regulation of cellular processGO:00485232830.023
cellular amine metabolic processGO:004410620.023
cellular response to molecule of bacterial originGO:007121930.022
negative regulation of kinase activityGO:003367340.022
neurotransmitter secretionGO:000726920.022
carbohydrate homeostasisGO:003350010.021
regulation of lipase activityGO:006019120.021
rna metabolic processGO:00160702190.021
regulation of postsynaptic membrane potentialGO:006007810.021
lipid oxidationGO:003444010.020
cardiac muscle cell developmentGO:0055013200.020
chordate embryonic developmentGO:00430092710.020
cell proliferationGO:0008283800.020
multicellular organism growthGO:003526440.020
negative regulation of response to stimulusGO:00485851040.020
carboxylic acid metabolic processGO:0019752220.020
cellular protein modification processGO:00064641000.020
antimicrobial humoral responseGO:001973020.019
protein complex biogenesisGO:0070271300.019
neurotransmitter transportGO:000683620.019
cellular biogenic amine metabolic processGO:000657620.019
regulation of cell matrix adhesionGO:000195210.019
glucose homeostasisGO:004259310.019
organelle fusionGO:004828430.019
Fly
small molecule metabolic processGO:0044281770.019
muscle organ developmentGO:00075171010.019
biosynthetic processGO:00090582940.018
cell migrationGO:00164772370.018
response to amino acidGO:004320020.018
regulation of neurotransmitter transportGO:005158810.018
regulation of phGO:000688530.018
regulation of metabolic processGO:00192223590.018
regulation of transcription dna templatedGO:00063552130.018
oxoacid metabolic processGO:0043436310.018
response to ketoneGO:190165410.018
response to chemicalGO:00422213200.018
single organism organelle organizationGO:19025891990.018
Fly
adherens junction organizationGO:003433240.018
regulation of receptor activityGO:001046920.017
myelinationGO:0042552180.017
Mouse
regulation of multicellular organismal processGO:00512392770.017
negative regulation of secretion by cellGO:190353120.017
adherens junction assemblyGO:003433310.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
regulation of cellular biosynthetic processGO:00313262450.017
regulation of developmental processGO:00507932470.017
locomotory behaviorGO:0007626340.017
regulation of cell deathGO:00109411030.017
guanosine containing compound metabolic processGO:190106840.017
synapsisGO:000712910.017
regulation of protein complex assemblyGO:004325430.017
cellular response to biotic stimulusGO:007121630.017
chemical homeostasisGO:0048878490.017
cell substrate junction assemblyGO:000704420.016
ion transmembrane transportGO:0034220910.016
cellular nitrogen compound metabolic processGO:00346412900.016
small molecule catabolic processGO:004428230.016
regulation of cellular component biogenesisGO:0044087120.016
neuron developmentGO:00486662620.016
regulation of rac protein signal transductionGO:003502010.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
nucleobase containing compound metabolic processGO:00061392740.016
regulation of filopodium assemblyGO:005148920.016
negative regulation of reproductive processGO:200024230.016
dna biosynthetic processGO:007189730.016
protein dephosphorylationGO:000647030.016
regulation of cell shapeGO:000836010.016
skeletal muscle thin filament assemblyGO:003024040.015
centrosome localizationGO:005164210.015
negative regulation of epithelial cell proliferationGO:005068010.015
pigmentationGO:0043473850.015
membrane fusionGO:006102520.015
Fly
cell projection organizationGO:00300302840.015
protein localization to plasma membraneGO:007265910.015
regulation of reproductive processGO:200024140.015
cellular response to decreased oxygen levelsGO:003629410.015
positive regulation of muscle cell differentiationGO:005114910.015
striated muscle tissue developmentGO:00147061100.015
chromosome organizationGO:0051276310.015
apical junction assemblyGO:004329710.015
regulation of establishment of protein localizationGO:007020140.015
negative regulation of biological processGO:00485193040.015
regulation of transmembrane transporter activityGO:002289820.015
organic acid metabolic processGO:0006082310.015
muscle tissue developmentGO:00605371100.015
positive regulation of striated muscle cell differentiationGO:005115510.015
response to nitrogen compoundGO:1901698190.015
heterocycle metabolic processGO:00464832900.015
amine metabolic processGO:000930820.014
multi organism processGO:00517041340.014
negative regulation of mapk cascadeGO:004340940.014
organism emergence from protective structureGO:007168440.014
peptidyl serine phosphorylationGO:001810510.014
intracellular signal transductionGO:0035556850.014
Mouse
regulation of signal transductionGO:00099662250.014
cellular protein metabolic processGO:00442671290.014
regulation of protein transportGO:005122330.014
glycerolipid biosynthetic processGO:004501710.014
fertilizationGO:000956630.014
cellular response to hypoxiaGO:007145610.014
water homeostasisGO:003010440.013
rna localizationGO:000640340.013
inflammatory responseGO:000695480.013
regulation of cell activationGO:005086510.013
negative regulation of macromolecule metabolic processGO:0010605760.013
response to bacteriumGO:0009617580.013
cellular response to oxygen levelsGO:007145310.013
schwann cell developmentGO:001404490.013
nitrogen compound metabolic processGO:00068073190.013
regulation of phosphate metabolic processGO:0019220430.013
peptidyl lysine methylationGO:001802230.013
osteoclast differentiationGO:003031610.013
synaptic vesicle transportGO:004848910.013
stem cell divisionGO:001714510.013
inorganic cation transmembrane transportGO:0098662500.013
gtp catabolic processGO:000618420.012
regulation of stem cell proliferationGO:007209120.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.012
response to radiationGO:0009314510.012
cell junction organizationGO:0034330110.012
cellular response to organic substanceGO:00713101050.012
phagocytosis engulfmentGO:000691110.012
programmed cell deathGO:00125011190.012
skeletal myofibril assemblyGO:001486670.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
fatty acid oxidationGO:001939510.012
exocytosisGO:000688710.012
kidney developmentGO:0001822920.012
positive regulation of cell communicationGO:0010647560.012
cellular component disassemblyGO:002241110.012
membrane invaginationGO:001032410.011
phosphate containing compound metabolic processGO:00067961080.011
Yeast Mouse Fly
response to hypoxiaGO:0001666250.011
regulation of rho protein signal transductionGO:003502320.011
cellular protein complex assemblyGO:0043623190.011
regulation of multicellular organism growthGO:004001440.011
inorganic ion transmembrane transportGO:0098660570.011
regulation of mitochondrion organizationGO:001082110.011
regulation of response to oxidative stressGO:190288220.011
determination of left right symmetryGO:00073681790.011
regulation of circadian rhythmGO:004275240.011
centrosome organizationGO:005129710.011
cell deathGO:00082191210.011
protein polyubiquitinationGO:000020940.011
protein localization to cell surfaceGO:003439430.011
organic substance transportGO:0071702580.011
deathGO:00162651210.011
response to endogenous stimulusGO:0009719830.011
muscle system processGO:0003012200.011
hormone secretionGO:004687920.011
meiotic cell cycle processGO:190304630.011
muscle structure developmentGO:00610611960.011
renal system developmentGO:0072001940.011
regulation of skeletal muscle fiber developmentGO:004874220.011
nucleic acid metabolic processGO:00903042440.011
regulation of apoptotic processGO:0042981980.011
pigment granule organizationGO:004875340.011
cell motilityGO:00488702440.011
response to corticosteroidGO:003196010.011
regulation of cell substrate adhesionGO:001081010.010
cellular macromolecule biosynthetic processGO:00346452240.010
cellular protein catabolic processGO:004425740.010
positive regulation of epithelial cell proliferationGO:005067910.010
negative regulation of multi organism processGO:004390130.010
regulation of production of molecular mediator of immune responseGO:000270010.010
cytosolic calcium ion transportGO:006040130.010
protein acetylationGO:000647320.010
aorta developmentGO:003590440.010
histone lysine demethylationGO:007007620.010
extrinsic apoptotic signaling pathwayGO:009719130.010
regulation of cytoplasmic transportGO:190364940.010
negative regulation of gene expressionGO:0010629650.010
positive regulation of immune effector processGO:000269930.010
regulation of nitrogen compound metabolic processGO:00511712510.010
response to decreased oxygen levelsGO:0036293250.010
cardiac muscle myosin thick filament assemblyGO:007169010.010

pikfyve disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.017
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
musculoskeletal system diseaseDOID:1700.012
heart diseaseDOID:11400.012
muscular diseaseDOID:008000000.012
cardiomyopathyDOID:005070000.012
cardiovascular system diseaseDOID:128700.012
disease of anatomical entityDOID:700.012
intrinsic cardiomyopathyDOID:006003600.012