Danio rerio

39 known processes

dtl

denticleless homolog (Drosophila)

(Aliases: cb151,wu:fb54b02,chunp6871)

dtl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycle processGO:1903047480.488
positive regulation of cell cycleGO:004578730.385
cell cycleGO:0007049930.307
negative regulation of nuclear divisionGO:005178430.303
larval developmentGO:000216420.272
Worm
regulation of meiotic cell cycleGO:005144510.258
cellular nitrogen compound metabolic processGO:00346412900.246
Human
cell cycle processGO:0022402530.240
negative regulation of cell cycle processGO:001094890.231
sister chromatid segregationGO:000081960.214
negative regulation of mitosisGO:004583930.207
negative regulation of cellular processGO:00485232830.177
regulation of mitotic cell cycle phase transitionGO:190199080.170
dna biosynthetic processGO:007189730.170
Human
regulation of cell cycle phase transitionGO:190198780.164
organelle organizationGO:00069962270.162
g2 m transition of mitotic cell cycleGO:000008640.158
regulation of cell cycleGO:0051726520.155
cellular macromolecule metabolic processGO:00442603910.141
Human
cytoskeleton organizationGO:0007010960.133
g1 s transition of mitotic cell cycleGO:000008210.128
regulation of signal transductionGO:00099662250.119
mitotic cell cycle embryonicGO:004544820.116
oocyte maturationGO:000155640.111
mitotic dna integrity checkpointGO:004477440.109
regulation of mitotic cell cycleGO:0007346250.104
ubiquitin dependent protein catabolic processGO:000651130.092
Human
single organism reproductive processGO:0044702400.088
Worm
mitotic sister chromatid segregationGO:000007060.088
tube morphogenesisGO:00352393490.087
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.087
signal transductionGO:00071654550.085
regulation of chromosome segregationGO:005198310.085
regulation of cellular component organizationGO:0051128860.084
phosphorus metabolic processGO:00067931090.083
cellular component biogenesisGO:00440851780.082
meiotic chromosome segregationGO:004513230.082
negative regulation of mitotic cell cycleGO:0045930110.081
regulation of nitrogen compound metabolic processGO:00511712510.080
stem cell maintenanceGO:001982740.079
modification dependent macromolecule catabolic processGO:004363230.074
Human
nitrogen compound metabolic processGO:00068073190.073
Human
cellular biosynthetic processGO:00442492860.073
Human
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.072
organelle fissionGO:0048285230.072
negative regulation of response to stimulusGO:00485851040.071
reproductionGO:0000003400.071
Worm
microtubule polymerizationGO:004678520.070
negative regulation of biological processGO:00485193040.070
phosphate containing compound metabolic processGO:00067961080.070
regulation of mitosisGO:000708890.070
microtubule organizing center organizationGO:003102310.068
macromolecular complex assemblyGO:0065003350.068
cellular nitrogen compound biosynthetic processGO:00442712180.067
Human
mitotic nuclear divisionGO:0007067180.066
centrosome organizationGO:005129710.065
organic substance biosynthetic processGO:19015762890.065
Human
protein complex assemblyGO:0006461300.064
growthGO:00400071740.064
Worm
negative regulation of cell cycleGO:0045786140.063
spindle assemblyGO:005122520.060
cellular aromatic compound metabolic processGO:00067252950.059
Human
response to stressGO:00069502630.058
negative regulation of chromosome organizationGO:200125110.058
negative regulation of cell communicationGO:0010648960.058
chromosome segregationGO:0007059120.057
regulation of protein catabolic processGO:004217610.056
meiosis iGO:000712710.055
cell cycle g2 m phase transitionGO:004483940.054
single organism metabolic processGO:00447102170.054
Human
cellular protein metabolic processGO:00442671290.054
Human
stem cell fate commitmentGO:004886510.053
locomotionGO:00400113130.053
Worm
mitotic cell cycleGO:0000278640.052
digestive system developmentGO:00551232890.052
dna metabolic processGO:0006259270.052
Human
multicellular organism growthGO:003526440.052
Worm
protein metabolic processGO:00195381830.051
Human
fertilizationGO:000956630.051
regulation of primary metabolic processGO:00800903110.049
spindle assembly involved in mitosisGO:009030710.049
cell cycle g1 s phase transitionGO:004484310.049
modification dependent protein catabolic processGO:001994130.048
Human
organelle assemblyGO:00709251100.048
regulation of cellular metabolic processGO:00313233200.046
localization of cellGO:00516742440.046
regulation of organelle organizationGO:0033043290.045
macromolecular complex subunit organizationGO:0043933740.044
regulation of rna biosynthetic processGO:20011412130.043
meiotic nuclear divisionGO:000712640.043
meiotic cell cycle processGO:190304630.042
microtubule cytoskeleton organization involved in mitosisGO:190285010.041
protein complex subunit organizationGO:0071822460.041
chromosome organizationGO:0051276310.040
regulation of cell communicationGO:00106462320.040
negative regulation of cell divisionGO:005178240.039
regulation of metabolic processGO:00192223590.039
regulation of cellular biosynthetic processGO:00313262450.039
regulation of cytoskeleton organizationGO:0051493110.039
nuclear divisionGO:0000280230.039
cellular protein catabolic processGO:004425740.039
Human
protein polymerizationGO:005125840.037
regulation of response to stimulusGO:00485832690.037
single organism organelle organizationGO:19025891990.037
regulation of cell cycle processGO:0010564200.037
immune system processGO:00023762410.037
response to uvGO:000941130.037
Human
response to amino acidGO:004320020.036
regulation of biological qualityGO:00650082630.036
centrosome cycleGO:000709810.035
rna metabolic processGO:00160702190.035
single organism biosynthetic processGO:0044711710.035
Human
mitotic metaphase plate congressionGO:000708010.035
negative regulation of signal transductionGO:0009968940.034
cell divisionGO:0051301200.033
oocyte developmentGO:0048599140.032
cellular macromolecule biosynthetic processGO:00346452240.032
Human
regulation of catalytic activityGO:0050790550.032
protein modification processGO:00362111000.032
Human
male meiosisGO:000714020.031
spindle assembly involved in meiosisGO:009030610.031
immunoglobulin mediated immune responseGO:001606430.031
regulation of cell divisionGO:0051302120.031
regulation of nuclear divisionGO:005178390.031
regulation of protein ubiquitinationGO:003139630.031
gland developmentGO:00487321430.031
maintenance of locationGO:005123540.031
regulation of microtubule cytoskeleton organizationGO:007050730.030
sensory organ developmentGO:00074233930.028
cell fate commitmentGO:0045165990.027
embryo development ending in birth or egg hatchingGO:00097922710.027
Worm
immune system developmentGO:00025201910.027
organic cyclic compound biosynthetic processGO:19013622230.026
Human
positive regulation of muscle organ developmentGO:004863610.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
cell cycle checkpointGO:000007570.026
regulation of bindingGO:005109830.026
nucleobase containing compound metabolic processGO:00061392740.025
Human
cellular protein modification processGO:00064641000.024
Human
developmental growthGO:00485891660.024
Worm
cytokinesisGO:000091030.024
positive regulation of cellular processGO:00485222010.024
protein complex biogenesisGO:0070271300.023
cell surface receptor signaling pathwayGO:00071663250.023
cardiac atrium developmentGO:000323040.023
nucleobase containing compound biosynthetic processGO:00346542050.023
Human
cellular component disassemblyGO:002241110.023
negative regulation of signalingGO:0023057960.023
heterocycle biosynthetic processGO:00181302150.023
Human
chromosome localizationGO:005000020.022
negative regulation of dna metabolic processGO:005105340.022
regulation of developmental processGO:00507932470.022
Worm
positive regulation of catabolic processGO:000989640.022
proteolysis involved in cellular protein catabolic processGO:005160330.022
Human
nucleic acid metabolic processGO:00903042440.022
Human
mitotic cell cycle phase transitionGO:004477290.021
heart developmentGO:00075073130.021
programmed cell deathGO:00125011190.021
mitotic dna damage checkpointGO:004477340.021
liver developmentGO:0001889960.021
meiotic spindle organizationGO:000021210.021
somatic cell dna recombinationGO:001644410.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
macromolecule modificationGO:00434121110.020
Human
determination of bilateral symmetryGO:00098552040.020
cell migration involved in gastrulationGO:0042074790.019
digestive tract developmentGO:00485652650.019
proteasomal protein catabolic processGO:001049820.019
positive regulation of nucleoside metabolic processGO:004597910.019
muscle cell developmentGO:00550011150.019
heterocycle metabolic processGO:00464832900.019
Human
regulation of protein complex assemblyGO:004325430.019
regulation of multicellular organismal processGO:00512392770.019
Worm
multi organism processGO:00517041340.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of signalingGO:00230512350.018
positive regulation of transportGO:005105020.018
response to woundingGO:00096111160.018
cell deathGO:00082191210.018
aromatic compound biosynthetic processGO:00194382170.018
Human
biosynthetic processGO:00090582940.018
Human
cellular amine metabolic processGO:004410620.018
agingGO:000756820.018
negative regulation of metabolic processGO:0009892860.017
regulation of macromolecule metabolic processGO:00602553170.017
deathGO:00162651210.017
establishment of organelle localizationGO:0051656450.017
tissue remodelingGO:004877140.017
cell proliferationGO:0008283800.017
amine metabolic processGO:000930820.017
positive regulation of cellular catabolic processGO:003133130.016
response to biotic stimulusGO:0009607970.016
negative regulation of epithelial cell differentiationGO:003085720.016
organelle localizationGO:0051640490.016
regulation of cell shapeGO:000836010.016
production of molecular mediator of immune responseGO:000244020.016
primary neural tube formationGO:001402010.016
regulation of purine nucleotide catabolic processGO:003312120.016
microtubule cytoskeleton organizationGO:0000226330.016
response to external biotic stimulusGO:0043207970.016
response to abiotic stimulusGO:00096281220.015
Human
organic cyclic compound metabolic processGO:19013603010.015
Human
b cell mediated immunityGO:001972430.015
regulation of tube sizeGO:003515020.015
cell motilityGO:00488702440.015
double strand break repairGO:000630230.015
cell migrationGO:00164772370.015
regulation of transcription dna templatedGO:00063552130.015
positive regulation of purine nucleotide catabolic processGO:003312310.014
mitotic cell cycle checkpointGO:000709350.014
dna modificationGO:000630480.014
single fertilizationGO:000733830.014
establishment of localizationGO:00512342440.014
Worm
oxoacid metabolic processGO:0043436310.014
stem cell differentiationGO:00488631170.014
regulation of gtpase activityGO:004308720.014
regulation of cellular protein metabolic processGO:0032268520.014
regulation of intracellular signal transductionGO:1902531570.014
cellular response to decreased oxygen levelsGO:003629410.014
lipoprotein catabolic processGO:004215910.014
peptidyl threonine modificationGO:001821010.014
intracellular signal transductionGO:0035556850.014
microtubule polymerization or depolymerizationGO:003110930.014
cellular response to stressGO:0033554620.014
g2 dna damage checkpointGO:003157230.013
regulation of dna replicationGO:000627530.013
regulation of phosphorus metabolic processGO:0051174430.013
response to endogenous stimulusGO:0009719830.013
gene expressionGO:00104672520.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
chromatin organizationGO:0006325220.013
immunoglobulin productionGO:000237710.013
cellular protein complex assemblyGO:0043623190.013
phagocytosisGO:000690930.013
sex determinationGO:000753010.013
eye developmentGO:00016542770.013
negative regulation of transcription dna templatedGO:0045892450.013
organelle fusionGO:004828430.013
stem cell developmentGO:0048864820.013
regenerationGO:0031099910.012
regulation of protein modification processGO:0031399290.012
ras protein signal transductionGO:000726570.012
regulation of programmed cell deathGO:00430671010.012
dna methylation on cytosineGO:003277630.012
positive regulation of cell divisionGO:005178120.012
striated muscle cell differentiationGO:00511461290.012
developmental process involved in reproductionGO:0003006270.012
Worm
meiosis iiGO:000713510.012
negative regulation of catalytic activityGO:0043086210.012
apoptotic processGO:00069151160.012
vesicle mediated transportGO:0016192220.012
Worm
cell substrate adhesionGO:003158940.012
negative regulation of cell cycle phase transitionGO:190198850.012
immune responseGO:0006955280.012
negative regulation of cellular metabolic processGO:0031324770.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124380.012
regulation of cellular protein catabolic processGO:190336210.011
negative regulation of histone methylationGO:003106110.011
negative regulation of catabolic processGO:000989530.011
rna biosynthetic processGO:00327741810.011
regulation of localizationGO:00328791040.011
positive regulation of gtp catabolic processGO:003312610.011
small molecule metabolic processGO:0044281770.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
cellular protein complex disassemblyGO:004362410.011
nitric oxide biosynthetic processGO:000680920.011
morphogenesis of an epitheliumGO:00020093330.011
negative regulation of mitotic cell cycle phase transitionGO:190199150.011
response to acid chemicalGO:0001101170.011
macromolecular complex disassemblyGO:003298410.011
establishment of protein localization to organelleGO:007259440.011
regulation of gene expressionGO:00104682650.011
regulation of stem cell differentiationGO:200073640.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
cellular amino acid metabolic processGO:000652070.011
negative regulation of gene expressionGO:0010629650.011
macromolecule localizationGO:0033036540.011
regulation of anatomical structure morphogenesisGO:00226031300.011
protein depolymerizationGO:005126110.011
intracellular estrogen receptor signaling pathwayGO:003052030.010
guanosine containing compound catabolic processGO:190106920.010
hepaticobiliary system developmentGO:0061008980.010
regulation of cell differentiationGO:00455951420.010
dna alkylationGO:000630580.010
germ line stem cell divisionGO:004207810.010
single organism localizationGO:19025782250.010
cellular ketone metabolic processGO:0042180110.010
regulation of dna templated transcription in response to stressGO:004362000.010
response to organic substanceGO:00100331530.010

dtl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.020
physical disorderDOID:008001500.018
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016