Danio rerio

64 known processes

pias4a

protein inhibitor of activated STAT, 4a

(Aliases: zgc:66410,wu:fi18c10,wu:fi20e09,wu:fk93f11,fc54c11,pias4,wu:fc54c11)

pias4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nitrogen compound metabolic processGO:00511712510.433
Mouse
organic cyclic compound biosynthetic processGO:19013622230.365
Mouse
rna metabolic processGO:00160702190.295
Mouse
regulation of response to stimulusGO:00485832690.277
regulation of cellular biosynthetic processGO:00313262450.264
Mouse
regulation of rna biosynthetic processGO:20011412130.261
Mouse
regulation of gene expressionGO:00104682650.259
Mouse
regulation of response to nutrient levelsGO:003210710.258
regulation of macromolecule biosynthetic processGO:00105562250.253
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.232
Mouse
regulation of metabolic processGO:00192223590.209
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.207
Mouse
transcription dna templatedGO:00063511810.205
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.190
Mouse
biosynthetic processGO:00090582940.188
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.186
Mouse
regulation of macromolecule metabolic processGO:00602553170.183
Mouse
cellular macromolecule biosynthetic processGO:00346452240.180
Mouse
macromolecule biosynthetic processGO:00090592270.174
Mouse
organic cyclic compound metabolic processGO:19013603010.166
Mouse
heterocycle biosynthetic processGO:00181302150.159
Mouse
response to stressGO:00069502630.157
nucleic acid metabolic processGO:00903042440.157
Mouse
positive regulation of jun kinase activityGO:004350720.156
regulation of signal transductionGO:00099662250.151
positive regulation of map kinase activityGO:004340630.137
larval developmentGO:000216420.137
cellular aromatic compound metabolic processGO:00067252950.135
Mouse
rna biosynthetic processGO:00327741810.133
Mouse
nitrogen compound metabolic processGO:00068073190.132
Mouse
stem cell maintenanceGO:001982740.129
regulation of transcription dna templatedGO:00063552130.127
Mouse
organic substance biosynthetic processGO:19015762890.123
Mouse
cellular response to extracellular stimulusGO:003166820.120
female sex differentiationGO:004666040.117
aromatic compound biosynthetic processGO:00194382170.117
Mouse
regulation of cellular metabolic processGO:00313233200.103
Mouse
gene expressionGO:00104672520.103
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.101
Mouse
positive regulation of stress activated mapk cascadeGO:003287430.101
chromosome organizationGO:0051276310.094
cell part morphogenesisGO:00329902460.093
cellular biosynthetic processGO:00442492860.091
Mouse
negative regulation of cellular metabolic processGO:0031324770.091
Mouse
regulation of cell communicationGO:00106462320.089
positive regulation of jnk cascadeGO:004633030.087
cellular macromolecule metabolic processGO:00442603910.085
Mouse
immune system processGO:00023762410.084
embryonic organ developmentGO:00485683810.084
digestive system developmentGO:00551232890.084
negative regulation of cellular processGO:00485232830.083
regulation of stem cell differentiationGO:200073640.082
regionalizationGO:00030022740.082
signal transductionGO:00071654550.081
regulation of biosynthetic processGO:00098892500.080
Mouse
cellular nitrogen compound metabolic processGO:00346412900.079
Mouse
morphogenesis of an epitheliumGO:00020093330.078
regulation of signalingGO:00230512350.077
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.076
regulation of primary metabolic processGO:00800903110.076
Mouse
digestive tract morphogenesisGO:00485462310.076
nucleobase containing compound metabolic processGO:00061392740.075
Mouse
negative regulation of metabolic processGO:0009892860.075
Mouse
nuclear transportGO:005116940.070
protein modification processGO:00362111000.070
Mouse
intracellular signal transductionGO:0035556850.067
Mouse
agingGO:000756820.067
cellular protein metabolic processGO:00442671290.065
Mouse
response to biotic stimulusGO:0009607970.064
response to external biotic stimulusGO:0043207970.064
regulation of protein complex assemblyGO:004325430.064
regulation of multicellular organism growthGO:004001440.062
single organism metabolic processGO:00447102170.061
multicellular organism growthGO:003526440.060
oxoacid metabolic processGO:0043436310.058
protein metabolic processGO:00195381830.058
Mouse
digestive tract developmentGO:00485652650.058
single organism nuclear importGO:190259330.057
cellular response to starvationGO:000926710.057
cell projection organizationGO:00300302840.056
cellular response to organic substanceGO:00713101050.054
regulation of response to extracellular stimulusGO:003210410.054
p38mapk cascadeGO:003806610.053
regulation of cellular ketone metabolic processGO:001056570.051
neuron projection developmentGO:00311751800.050
establishment of protein localization to organelleGO:007259440.049
neuron differentiationGO:00301823530.048
specification of symmetryGO:00097992040.048
cell projection morphogenesisGO:00488582440.047
small molecule metabolic processGO:0044281770.047
gastrulationGO:00073692080.046
tube morphogenesisGO:00352393490.046
cellular response to external stimulusGO:007149620.046
sensory organ developmentGO:00074233930.046
regulation of cellular amino acid metabolic processGO:000652100.045
positive regulation of nitrogen compound metabolic processGO:0051173690.045
axon developmentGO:00615641660.045
single organism localizationGO:19025782250.044
generation of neuronsGO:00486993850.044
response to external stimulusGO:00096052640.044
macroautophagyGO:001623610.043
cellular response to biotic stimulusGO:007121630.042
nucleic acid templated transcriptionGO:00976591810.042
Mouse
organic acid metabolic processGO:0006082310.042
negative regulation of macromolecule metabolic processGO:0010605760.041
Mouse
response to chemicalGO:00422213200.041
defense responseGO:0006952470.041
cellular response to nutrient levelsGO:003166920.041
regulation of rna metabolic processGO:00512522240.040
Mouse
regulation of cellular protein metabolic processGO:0032268520.040
homeostasis of number of cellsGO:0048872620.040
negative regulation of cellular catabolic processGO:003133030.040
negative regulation of protein phosphorylationGO:000193340.040
alternative mrna splicing via spliceosomeGO:000038010.040
cell surface receptor signaling pathwayGO:00071663250.040
cellular component morphogenesisGO:00329893360.039
protein localization to nucleusGO:003450430.039
negative regulation of biological processGO:00485193040.039
positive regulation of cellular catabolic processGO:003133130.039
positive regulation of dna metabolic processGO:005105410.038
macromolecule modificationGO:00434121110.038
Mouse
regulation of dendrite developmentGO:005077330.038
amine metabolic processGO:000930820.037
macromolecular complex subunit organizationGO:0043933740.037
germ line stem cell divisionGO:004207810.037
transcription from rna polymerase ii promoterGO:0006366800.037
Mouse
carboxylic acid metabolic processGO:0019752220.037
positive regulation of catabolic processGO:000989640.037
establishment of localizationGO:00512342440.037
heterocycle metabolic processGO:00464832900.036
Mouse
heart developmentGO:00075073130.035
pigmentationGO:0043473850.035
regulation of peptidyl tyrosine phosphorylationGO:005073010.035
activation of mapk activityGO:000018730.035
organelle organizationGO:00069962270.034
regulation of mrna splicing via spliceosomeGO:004802430.034
cell morphogenesis involved in neuron differentiationGO:00486671630.034
regulation of phosphorus metabolic processGO:0051174430.033
axonogenesisGO:00074091520.033
cell growthGO:0016049570.033
autophagyGO:000691440.032
organonitrogen compound metabolic processGO:1901564740.032
skin developmentGO:0043588540.032
epidermis developmentGO:0008544480.032
protein importGO:001703830.032
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.031
single organism organelle organizationGO:19025891990.031
neuron developmentGO:00486662620.031
establishment of endothelial barrierGO:006102830.031
positive regulation of biological processGO:00485182530.031
Mouse
cell morphogenesisGO:00009022890.030
proteolysis involved in cellular protein catabolic processGO:005160330.030
stem cell developmentGO:0048864820.030
embryonic organ morphogenesisGO:00485622740.030
hemopoiesisGO:00300971830.030
positive regulation of i kappab kinase nf kappab signalingGO:004312330.029
nuclear importGO:005117030.029
macromolecule methylationGO:0043414190.029
cellular ketone metabolic processGO:0042180110.029
endodermal cell differentiationGO:0035987190.029
negative regulation of gene expressionGO:0010629650.029
Mouse
female gonad developmentGO:000858540.029
establishment of apical basal cell polarityGO:003508920.028
negative regulation of protein kinase activityGO:000646940.028
cell migrationGO:00164772370.028
determination of bilateral symmetryGO:00098552040.028
negative regulation of catabolic processGO:000989530.028
positive regulation of cellular biosynthetic processGO:0031328680.027
signal transduction by phosphorylationGO:0023014180.027
regulation of cellular response to stressGO:0080135200.027
Mouse
positive regulation of chromatin modificationGO:190331010.027
phosphorylationGO:0016310690.027
cellular amine metabolic processGO:004410620.027
negative regulation of stem cell differentiationGO:200073720.026
regulation of cellular amine metabolic processGO:003323800.026
protein targeting to nucleusGO:004474430.026
regulation of cellular protein catabolic processGO:190336210.026
response to fluid shear stressGO:003440520.026
cell cycleGO:0007049930.026
positive regulation of response to stimulusGO:0048584800.026
Mouse
somatic stem cell maintenanceGO:003501910.025
response to nutrientGO:000758430.025
germ line stem cell maintenanceGO:003071820.025
development of primary female sexual characteristicsGO:004654540.025
immune system developmentGO:00025201910.025
regulation of protein metabolic processGO:0051246560.024
cellular amino acid metabolic processGO:000652070.024
positive regulation of immune effector processGO:000269930.024
organelle localizationGO:0051640490.024
cellular response to stressGO:0033554620.024
Mouse
neuron projection morphogenesisGO:00488121610.024
negative regulation of cytoplasmic transportGO:190365020.024
regulation of immune system processGO:0002682340.023
regulation of cellular component organizationGO:0051128860.023
positive regulation of rna metabolic processGO:0051254590.023
erythrocyte differentiationGO:0030218540.023
regulation of transferase activityGO:0051338160.023
regulation of biological qualityGO:00650082630.023
positive regulation of lymphocyte mediated immunityGO:000270810.023
cellular protein modification processGO:00064641000.023
Mouse
chromatin organizationGO:0006325220.023
rna polyadenylationGO:004363120.023
positive regulation of cellular amine metabolic processGO:003324000.023
embryo development ending in birth or egg hatchingGO:00097922710.023
regulation of autophagyGO:001050630.022
regulation of phosphorylationGO:0042325260.022
cardiac cell fate commitmentGO:006091110.022
retinoic acid metabolic processGO:004257390.022
cellular response to chemical stimulusGO:00708871570.022
negative regulation of mapk cascadeGO:004340940.022
immune responseGO:0006955280.021
cell morphogenesis involved in differentiationGO:00009041950.021
post anal tail morphogenesisGO:0036342190.021
polarized epithelial cell differentiationGO:003085940.021
cellular component biogenesisGO:00440851780.021
regulation of p38mapk cascadeGO:190074410.021
synaptic target recognitionGO:000803910.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
locomotionGO:00400113130.021
regulation of cytoplasmic transportGO:190364940.021
camera type eye developmentGO:00430102220.021
maintenance of locationGO:005123540.021
reactive oxygen species biosynthetic processGO:190340910.020
reactive nitrogen species metabolic processGO:200105700.020
protein phosphorylationGO:0006468470.020
response to ketoneGO:190165410.020
mitotic cell cycle processGO:1903047480.020
regulation of reproductive processGO:200024140.020
regulation of jun kinase activityGO:004350630.020
cell motilityGO:00488702440.020
negative regulation of response to stimulusGO:00485851040.020
regulation of transcription from rna polymerase ii promoterGO:00063571140.020
Mouse
regulation of response to cytokine stimulusGO:006075930.019
positive regulation of cell cycleGO:004578730.019
regulation of gene expression epigeneticGO:0040029110.019
b cell activationGO:004211320.019
jnk cascadeGO:000725470.019
response to organic substanceGO:00100331530.019
regulation of dna replicationGO:000627530.019
response to glucoseGO:000974930.019
lipid storageGO:001991510.019
response to carbohydrateGO:000974330.019
organism emergence from protective structureGO:007168440.019
regulation of immune responseGO:0050776140.019
regulation of establishment or maintenance of cell polarityGO:003287820.019
mitotic cell cycleGO:0000278640.018
peptide transportGO:001583310.018
developmental cell growthGO:0048588520.018
regulation of calcium dependent cell cell adhesionGO:004658610.018
regulation of intracellular signal transductionGO:1902531570.018
Mouse
growthGO:00400071740.018
stem cell divisionGO:001714510.018
cytoskeleton organizationGO:0007010960.018
regulation of jnk cascadeGO:004632850.018
negative regulation of kinase activityGO:003367340.018
regulation of establishment of protein localizationGO:007020140.018
localization of cellGO:00516742440.018
actin filament bundle organizationGO:006157260.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
negative regulation of cell communicationGO:0010648960.018
regulation of cytokine productionGO:000181730.017
positive regulation of biosynthetic processGO:0009891680.017
positive regulation of signal transductionGO:0009967560.017
Mouse
regulation of mapk cascadeGO:0043408140.017
regulation of protein import into nucleusGO:004230620.017
gtp catabolic processGO:000618420.017
positive regulation of immune responseGO:0050778110.017
regulation of kinase activityGO:0043549150.017
regulation of cell differentiationGO:00455951420.017
negative regulation of chromosome organizationGO:200125110.017
cellular response to dna damage stimulusGO:0006974240.017
Mouse
nucleocytoplasmic transportGO:000691340.017
regulation of protein ubiquitinationGO:003139630.017
dna metabolic processGO:0006259270.017
negative regulation of chromatin modificationGO:190330910.017
stem cell fate commitmentGO:004886510.017
stem cell proliferationGO:007208940.017
negative regulation of rna biosynthetic processGO:1902679450.017
Mouse
positive regulation of cell activationGO:005086710.016
neuroblast differentiationGO:001401610.016
negative regulation of i kappab kinase nf kappab signalingGO:004312410.016
cell cycle processGO:0022402530.016
spermatid developmentGO:000728620.016
regulation of nucleocytoplasmic transportGO:004682220.016
regulation of response to stressGO:0080134360.016
protein localizationGO:0008104400.016
regulation of establishment of planar polarityGO:009017540.016
negative regulation of rna metabolic processGO:0051253480.016
Mouse
response to monosaccharideGO:003428430.016
negative regulation of nucleic acid templated transcriptionGO:1903507450.016
Mouse
response to oxidative stressGO:0006979110.016
negative regulation of jnk cascadeGO:004632910.016
developmental growthGO:00485891660.016
wnt signaling pathwayGO:0016055800.016
response to vitaminGO:003327330.016
i kappab kinase nf kappab signalingGO:000724940.015
negative regulation of macromolecule biosynthetic processGO:0010558480.015
Mouse
protein acetylationGO:000647320.015
negative chemotaxisGO:005091910.015
blood vessel developmentGO:00015682460.015
phagocytosisGO:000690930.015
pyruvate metabolic processGO:000609010.015
erythrocyte homeostasisGO:0034101550.015
internal peptidyl lysine acetylationGO:001839320.015
lamellipodium assemblyGO:003003210.015
wound healingGO:0042060900.015
negative regulation of transcription dna templatedGO:0045892450.015
Mouse
cellular protein catabolic processGO:004425740.015
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.015
Mouse
histone h3 k4 methylationGO:005156820.015
innate immune responseGO:0045087130.015
muscle organ developmentGO:00075171010.015
negative regulation of cell differentiationGO:0045596460.015
histone lysine methylationGO:0034968120.014
neuroblast proliferationGO:000740520.014
protein complex subunit organizationGO:0071822460.014
axon guidanceGO:0007411860.014
regulation of meiotic cell cycleGO:005144510.014
chromosome organization involved in meiosisGO:007019210.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
negative regulation of defense responseGO:003134820.014
protein dephosphorylationGO:000647030.014
regulation of reactive oxygen species metabolic processGO:200037720.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
regulation of nucleoside metabolic processGO:000911820.014
response to drugGO:004249330.014
tube closureGO:006060610.014
internal protein amino acid acetylationGO:000647520.014
rna localizationGO:000640340.014
regulation of stress activated protein kinase signaling cascadeGO:007030260.014
regulation of protein transportGO:005122330.014
regulation of protein catabolic processGO:004217610.014
membrane invaginationGO:001032410.013
regulation of cell activationGO:005086510.013
negative regulation of biosynthetic processGO:0009890550.013
Mouse
response to hexoseGO:000974630.013
neuronal stem cell maintenanceGO:009715020.013
modification dependent protein catabolic processGO:001994130.013
multi organism processGO:00517041340.013
cellular localizationGO:0051641970.013
dna templated transcription elongationGO:000635430.013
negative regulation of signal transductionGO:0009968940.013
inner ear developmentGO:00488391260.013
nuclear exportGO:005116810.013
regulation of catalytic activityGO:0050790550.013
ear developmentGO:00435831270.013
response to endogenous stimulusGO:0009719830.013
positive regulation of cellular component biogenesisGO:004408930.013
regulation of dendrite morphogenesisGO:004881430.013
establishment of monopolar cell polarityGO:006116220.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
phosphorus metabolic processGO:00067931090.013
positive regulation of histone modificationGO:003105810.013
positive regulation of cellular metabolic processGO:0031325940.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
chromatin modificationGO:0016568210.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
positive regulation of myeloid cell differentiationGO:004563920.013
phosphate containing compound metabolic processGO:00067961080.012
regulation of histone methylationGO:003106030.012
very long chain fatty acid metabolic processGO:000003840.012
hindbrain developmentGO:0030902910.012
chemotaxisGO:00069351040.012
epidermis morphogenesisGO:004873040.012
primary neural tube formationGO:001402010.012
regulation of multicellular organismal developmentGO:20000262230.012
regulation of tube sizeGO:003515020.012
positive regulation of epithelial cell proliferationGO:005067910.012
positive regulation of production of molecular mediator of immune responseGO:000270210.012
defense response to fungusGO:005083220.012
positive regulation of interferon beta productionGO:003272810.012
immunoglobulin mediated immune responseGO:001606430.012
cellular component assemblyGO:00226071700.012
regulation of leukocyte mediated immunityGO:000270310.012
regulation of circadian rhythmGO:004275240.012
peptide metabolic processGO:000651810.012
negative regulation of translationGO:001714810.012
cytokinesisGO:000091030.012
positive regulation of glucose transportGO:001082810.012
epithelial tube morphogenesisGO:00605621480.012
chordate embryonic developmentGO:00430092710.012
positive regulation of developmental processGO:0051094500.012
positive regulation of macromolecule metabolic processGO:0010604930.012
homeostatic processGO:00425921420.012
negative regulation of dna metabolic processGO:005105340.012
positive regulation of leukocyte mediated immunityGO:000270510.011
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
positive regulation of chromosome organizationGO:200125210.011
nuclear migrationGO:000709730.011
myeloid cell homeostasisGO:0002262560.011
pericardium developmentGO:006003910.011
head developmentGO:00603223030.011
determination of left right symmetryGO:00073681790.011
type i interferon productionGO:003260620.011
regulation of molecular functionGO:0065009700.011
Mouse
negative regulation of protein serine threonine kinase activityGO:007190120.011
wnt signaling pathway planar cell polarity pathwayGO:006007140.011
covalent chromatin modificationGO:0016569200.011
regulation of production of molecular mediator of immune responseGO:000270010.011
chemosensory behaviorGO:000763510.011
neuron projection guidanceGO:0097485860.011
peptidyl lysine methylationGO:001802230.011
negative regulation of endopeptidase activityGO:0010951100.011
spermatid differentiationGO:004851520.011
lamellipodium organizationGO:009758110.011
activation of immune responseGO:000225390.011
ribonucleoside monophosphate catabolic processGO:000915840.011
apoptotic processGO:00069151160.011
Mouse
positive regulation of transportGO:005105020.011
vasculature developmentGO:00019442780.011
negative regulation of intracellular protein transportGO:009031730.011
regulation of phosphate metabolic processGO:0019220430.011
regulation of wnt signaling pathwayGO:0030111530.011
behaviorGO:0007610740.010
actin filament based processGO:0030029640.010
peptidyl lysine trimethylationGO:001802310.010
cell fate commitment involved in formation of primary germ layerGO:0060795260.010
negative regulation of response to cytokine stimulusGO:006076120.010
establishment of localization in cellGO:0051649770.010
cell cycle g1 s phase transitionGO:004484310.010
response to hormoneGO:0009725480.010
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.010
positive regulation of cytokine productionGO:000181920.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
cellular response to organic cyclic compoundGO:0071407380.010
regulation of blood vessel sizeGO:005088020.010
synaptic growth at neuromuscular junctionGO:005112420.010
developmental growth involved in morphogenesisGO:0060560860.010
nucleoside monophosphate catabolic processGO:000912540.010
spindle assemblyGO:005122520.010
b cell mediated immunityGO:001972430.010
production of molecular mediator of immune responseGO:000244020.010
regulation of protein modification processGO:0031399290.010
regulation of receptor activityGO:001046920.010

pias4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
disease of metabolismDOID:001466700.012
organ system cancerDOID:005068600.011
endocrine gland cancerDOID:17000.011
disease of anatomical entityDOID:700.011