Danio rerio

0 known processes

sp8a

sp8 transcription factor a

(Aliases: sp8,cb459,sb:cb459,wu:fa96f05,wu:fa07g05,Sp8b,zgc:85841)

sp8a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dorsal ventral pattern formationGO:00099531250.799
Mouse
regionalizationGO:00030022740.741
Mouse
skeletal system developmentGO:00015011810.630
ectodermal placode morphogenesisGO:0071697320.547
morphogenesis of an epitheliumGO:00020093330.481
trigeminal nerve developmentGO:002155930.474
regulation of neuron differentiationGO:0045664560.436
neuron differentiationGO:00301823530.435
signal transductionGO:00071654550.415
Zebrafish
embryonic organ developmentGO:00485683810.409
central nervous system developmentGO:00074173870.374
regulation of axon extension involved in axon guidanceGO:004884160.351
regulation of nervous system developmentGO:0051960900.351
pectoral fin developmentGO:0033339500.326
Zebrafish
wound healingGO:0042060900.299
larval developmentGO:000216420.291
tube morphogenesisGO:00352393490.284
striated muscle cell developmentGO:00550021080.268
cellular macromolecule biosynthetic processGO:00346452240.250
regulation of cell communicationGO:00106462320.248
Zebrafish
regulation of biosynthetic processGO:00098892500.235
Fly
positive regulation of biological processGO:00485182530.235
Zebrafish
nucleobase containing compound biosynthetic processGO:00346542050.232
regulation of cell differentiationGO:00455951420.227
regulation of multicellular organismal processGO:00512392770.227
regulation of neurogenesisGO:0050767870.221
regulation of response to stimulusGO:00485832690.221
Zebrafish
cell projection morphogenesisGO:00488582440.219
cellular component morphogenesisGO:00329893360.212
rna metabolic processGO:00160702190.212
regulation of nitrogen compound metabolic processGO:00511712510.206
Fly
regulation of synapse assemblyGO:005196330.202
appendage morphogenesisGO:0035107560.201
Zebrafish Mouse Fly
generation of neuronsGO:00486993850.200
taxisGO:00423301090.199
embryonic pectoral fin morphogenesisGO:0035118240.198
Zebrafish
cellular response to chemical stimulusGO:00708871570.190
Zebrafish
embryonic organ morphogenesisGO:00485622740.186
regulation of multicellular organismal developmentGO:20000262230.184
appendage developmentGO:0048736800.171
Zebrafish Mouse Fly
regulation of cell morphogenesis involved in differentiationGO:0010769380.169
regulation of rna biosynthetic processGO:20011412130.163
Fly
sensory organ developmentGO:00074233930.154
chemotaxisGO:00069351040.149
fin developmentGO:0033333770.149
Zebrafish
fin morphogenesisGO:0033334530.146
Zebrafish
cell morphogenesis involved in neuron differentiationGO:00486671630.146
sensory organ morphogenesisGO:00905962000.139
heart developmentGO:00075073130.136
regulation of gene expressionGO:00104682650.134
Fly
specification of symmetryGO:00097992040.134
neuron projection guidanceGO:0097485860.133
cell part morphogenesisGO:00329902460.133
cell surface receptor signaling pathwayGO:00071663250.133
Zebrafish
stem cell developmentGO:0048864820.132
skeletal muscle organ developmentGO:0060538780.129
regulation of dendrite developmentGO:005077330.128
regulation of synapse organizationGO:005080730.127
regulation of cellular metabolic processGO:00313233200.126
Fly
stem cell differentiationGO:00488631170.126
response to stressGO:00069502630.125
muscle cell developmentGO:00550011150.122
cell morphogenesisGO:00009022890.122
multicellular organism growthGO:003526440.120
negative regulation of axon extension involved in axon guidanceGO:004884310.115
epidermis developmentGO:0008544480.114
positive regulation of cellular processGO:00485222010.114
Zebrafish
otic vesicle morphogenesisGO:0071600340.113
negative chemotaxisGO:005091910.113
determination of bilateral symmetryGO:00098552040.112
sympathetic nervous system developmentGO:004848530.110
neuron developmentGO:00486662620.109
muscle structure developmentGO:00610611960.108
cell projection organizationGO:00300302840.108
synaptic target recognitionGO:000803910.104
axon midline choice point recognitionGO:001619940.101
muscle cell differentiationGO:00426921390.101
neuron projection developmentGO:00311751800.101
regulation of cell developmentGO:00602841000.100
aromatic compound biosynthetic processGO:00194382170.100
inner ear developmentGO:00488391260.099
response to external stimulusGO:00096052640.096
rhombomere 5 developmentGO:002157140.096
organic substance biosynthetic processGO:19015762890.095
striated muscle cell differentiationGO:00511461290.094
organic cyclic compound biosynthetic processGO:19013622230.094
regulation of nucleic acid templated transcriptionGO:19035062130.092
Fly
camera type eye developmentGO:00430102220.092
dendrite developmentGO:001635890.092
embryonic limb morphogenesisGO:003032620.091
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.089
Fly
rna biosynthetic processGO:00327741810.087
response to xenobiotic stimulusGO:0009410450.085
gene expressionGO:00104672520.085
positive regulation of cell communicationGO:0010647560.084
Zebrafish
regulation of biological qualityGO:00650082630.083
negative regulation of axon guidanceGO:190266810.083
regulation of extent of cell growthGO:0061387290.081
hematopoietic or lymphoid organ developmentGO:00485341910.081
pectoral fin morphogenesisGO:0035138290.080
Zebrafish
cellular nitrogen compound biosynthetic processGO:00442712180.080
otic vesicle formationGO:0030916270.079
mesenchyme developmentGO:00604851270.078
biosynthetic processGO:00090582940.078
response to organic substanceGO:00100331530.076
Zebrafish
negative regulation of cell differentiationGO:0045596460.075
axon extensionGO:0048675450.075
negative regulation of chemotaxisGO:005092240.075
regulation of signal transductionGO:00099662250.075
Zebrafish
cell migrationGO:00164772370.073
transcription dna templatedGO:00063511810.072
nitrogen compound metabolic processGO:00068073190.072
developmental growthGO:00485891660.072
regulation of signalingGO:00230512350.070
Zebrafish
embryonic skeletal system developmentGO:0048706970.069
regulation of transcription dna templatedGO:00063552130.069
Fly
segmentationGO:0035282970.067
single organism metabolic processGO:00447102170.066
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574390.066
Zebrafish
regulation of locomotionGO:0040012550.066
head developmentGO:00603223030.066
synapse organizationGO:0050808210.064
regulation of anatomical structure morphogenesisGO:00226031300.063
neuron projection extensionGO:1990138450.062
nucleic acid metabolic processGO:00903042440.062
anterior posterior pattern specificationGO:00099521520.061
response to chemicalGO:00422213200.059
Zebrafish
regulation of metabolic processGO:00192223590.058
Fly
eye developmentGO:00016542770.057
stem cell maintenanceGO:001982740.057
response to lipidGO:0033993600.056
regulation of macromolecule metabolic processGO:00602553170.054
Fly
anterior posterior axon guidanceGO:003356450.053
negative regulation of cell morphogenesis involved in differentiationGO:001077180.053
cellular nitrogen compound metabolic processGO:00346412900.052
mesenchymal cell developmentGO:0014031780.052
regulation of macromolecule biosynthetic processGO:00105562250.052
Fly
cell motilityGO:00488702440.051
positive regulation of signal transductionGO:0009967560.051
Zebrafish
positive regulation of transportGO:005105020.051
vestibular receptor cell differentiationGO:006011430.050
single organism organelle organizationGO:19025891990.050
axon extension involved in axon guidanceGO:0048846100.050
blood vessel morphogenesisGO:00485142160.050
regulation of axonogenesisGO:0050770320.049
regulation of rna metabolic processGO:00512522240.049
Fly
cell fate specificationGO:0001708680.049
locomotionGO:00400113130.049
cartilage developmentGO:0051216960.047
cellular component movementGO:00069283350.047
regulation of neuron projection developmentGO:0010975400.047
positive regulation of macromolecule metabolic processGO:0010604930.047
neuron fate commitmentGO:0048663260.047
wnt signaling pathwayGO:0016055800.046
central nervous system neuron axonogenesisGO:0021955180.046
skin developmentGO:0043588540.045
negative regulation of stem cell differentiationGO:200073720.045
kupffer s vesicle developmentGO:0070121500.044
cell proliferationGO:0008283800.044
transcription from rna polymerase ii promoterGO:0006366800.043
heterocycle metabolic processGO:00464832900.043
amine metabolic processGO:000930820.042
tissue regenerationGO:0042246740.042
response to growth factorGO:0070848390.042
Zebrafish
midbrain developmentGO:0030901280.042
determination of dorsal ventral asymmetryGO:0048262340.042
epithelial to mesenchymal transitionGO:0001837210.042
negative regulation of macromolecule biosynthetic processGO:0010558480.041
peripheral nervous system developmentGO:0007422550.041
nucleic acid templated transcriptionGO:00976591810.041
neuron fate specificationGO:0048665200.040
retina morphogenesis in camera type eyeGO:0060042790.039
oxoacid metabolic processGO:0043436310.039
embryo development ending in birth or egg hatchingGO:00097922710.039
negative regulation of biological processGO:00485193040.039
neuron projection extension involved in neuron projection guidanceGO:1902284100.039
regulation of axon extensionGO:0030516240.039
response to woundingGO:00096111160.038
heart morphogenesisGO:00030071560.038
cellular component assemblyGO:00226071700.037
developmental process involved in reproductionGO:0003006270.036
negative regulation of cellular processGO:00485232830.036
axonogenesisGO:00074091520.036
negative regulation of neuron differentiationGO:0045665100.036
growthGO:00400071740.035
negative regulation of neuron projection developmentGO:001097790.035
hard palate developmentGO:006002240.034
cognitionGO:005089010.034
blood vessel developmentGO:00015682460.034
positive regulation of neurogenesisGO:0050769240.034
organic cyclic compound metabolic processGO:19013603010.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
Fly
chordate embryonic developmentGO:00430092710.033
regulation of cellular component movementGO:0051270550.033
regulation of cell sizeGO:0008361290.032
regulation of developmental processGO:00507932470.032
axon choice point recognitionGO:001619850.032
regulation of cellular response to growth factor stimulusGO:0090287350.032
Zebrafish
cortical actin cytoskeleton organizationGO:003086610.032
digestive tract developmentGO:00485652650.031
negative regulation of cell projection organizationGO:003134590.031
agingGO:000756820.031
protein targeting to nucleusGO:004474430.031
cellular response to xenobiotic stimulusGO:0071466350.031
cellular macromolecule metabolic processGO:00442603910.030
enzyme linked receptor protein signaling pathwayGO:00071671060.030
Zebrafish
regulation of localizationGO:00328791040.030
macromolecule biosynthetic processGO:00090592270.030
regulation of nucleocytoplasmic transportGO:004682220.029
negative regulation of nervous system developmentGO:0051961220.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
regulation of dendrite morphogenesisGO:004881430.029
embryonic pattern specificationGO:0009880440.029
regulation of primary metabolic processGO:00800903110.029
Fly
regulation of axon guidanceGO:190266780.028
positive regulation of translationGO:004572710.028
positive regulation of nervous system developmentGO:0051962250.028
nuclear transportGO:005116940.027
regulation of protein catabolic processGO:004217610.027
ear developmentGO:00435831270.027
regulation of stem cell differentiationGO:200073640.027
somite developmentGO:0061053960.026
embryonic skeletal system morphogenesisGO:0048704930.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.026
heterocycle biosynthetic processGO:00181302150.025
nucleobase containing compound metabolic processGO:00061392740.025
cellular response to molecule of bacterial originGO:007121930.025
otic vesicle developmentGO:0071599420.025
regulation of cellular component sizeGO:0032535300.025
developmental growth involved in morphogenesisGO:0060560860.025
negative regulation of locomotionGO:0040013180.025
regulation of cellular biosynthetic processGO:00313262450.024
Fly
connective tissue developmentGO:0061448990.024
retina development in camera type eyeGO:00600411460.024
positive regulation of molecular functionGO:0044093330.024
skeletal system morphogenesisGO:00487051020.024
eye morphogenesisGO:00485921440.023
regulation of cell motilityGO:2000145460.023
carboxylic acid metabolic processGO:0019752220.023
gland developmentGO:00487321430.023
regenerationGO:0031099910.023
negative regulation of neurogenesisGO:0050768200.023
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.023
negative regulation of cellular biosynthetic processGO:0031327550.023
cellular aromatic compound metabolic processGO:00067252950.023
axon guidanceGO:0007411860.023
central nervous system projection neuron axonogenesisGO:0021952150.023
epithelial cell differentiationGO:00308551160.023
positive regulation of response to stimulusGO:0048584800.023
Zebrafish
fin regenerationGO:0031101510.023
rhombomere developmentGO:0021546190.022
negative regulation of axonogenesisGO:005077170.022
cellular response to growth factor stimulusGO:0071363390.022
Zebrafish
immune system processGO:00023762410.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.021
regulation of intracellular signal transductionGO:1902531570.021
neuron projection morphogenesisGO:00488121610.021
axon developmentGO:00615641660.021
regulation of cell growthGO:0001558290.021
brain developmentGO:00074202930.021
mesenchymal cell differentiationGO:0048762870.020
regulation of cellular ketone metabolic processGO:001056570.020
bmp signaling pathwayGO:0030509520.020
central nervous system neuron differentiationGO:0021953740.020
positive regulation of locomotionGO:0040017140.020
cell migration involved in gastrulationGO:0042074790.020
neural crest cell developmentGO:0014032620.020
erk1 and erk2 cascadeGO:007037140.020
nuclear importGO:005117030.020
organelle organizationGO:00069962270.020
negative regulation of rna biosynthetic processGO:1902679450.020
negative regulation of signal transductionGO:0009968940.019
regulation of hormone secretionGO:004688320.019
positive regulation of cell adhesionGO:004578510.019
organic acid metabolic processGO:0006082310.019
regulation of intracellular protein transportGO:003315730.019
ear morphogenesisGO:0042471640.019
negative regulation of nucleic acid templated transcriptionGO:1903507450.019
regulation of protein targetingGO:190353320.019
embryonic skeletal joint developmentGO:007249830.019
positive regulation of synapse assemblyGO:005196510.019
cell substrate adhesionGO:003158940.019
nucleocytoplasmic transportGO:000691340.019
positive regulation of canonical wnt signaling pathwayGO:009026340.019
protein importGO:001703830.019
cellular component biogenesisGO:00440851780.018
response to vitaminGO:003327330.018
synaptic growth at neuromuscular junctionGO:005112420.018
otic placode formationGO:0043049230.018
cardioblast migration to the midline involved in heart field formationGO:006097570.018
digestive system developmentGO:00551232890.018
negative regulation of rna metabolic processGO:0051253480.018
negative regulation of biosynthetic processGO:0009890550.017
negative regulation of kinase activityGO:003367340.017
inner ear receptor cell differentiationGO:0060113290.017
autonomic nervous system developmentGO:0048483190.017
regulation of protein localization to nucleusGO:190018020.017
palate developmentGO:006002180.017
positive regulation of cell developmentGO:0010720250.017
endothelial cell migrationGO:0043542190.017
regulation of skeletal muscle fiber developmentGO:004874220.017
cell morphogenesis involved in differentiationGO:00009041950.016
macromolecular complex disassemblyGO:003298410.016
regulation of cellular amine metabolic processGO:003323800.016
regulation of epithelial to mesenchymal transitionGO:001071730.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.016
Zebrafish
cellular ketone metabolic processGO:0042180110.016
lateral inhibitionGO:004633110.016
embryonic appendage morphogenesisGO:0035113300.016
Zebrafish Mouse
extrinsic apoptotic signaling pathwayGO:009719130.016
cell fate commitmentGO:0045165990.016
regulation of embryonic developmentGO:0045995470.016
skeletal muscle tissue developmentGO:0007519670.016
positive regulation of cellular component biogenesisGO:004408930.016
epiboly involved in gastrulation with mouth forming secondGO:0055113350.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of protein transportGO:005122330.016
single organism nuclear importGO:190259330.016
regulation of cell morphogenesisGO:0022604420.016
regulation of cell activationGO:005086510.016
regulation of cellular component organizationGO:0051128860.016
keratinocyte differentiationGO:003021600.015
regulation of protein metabolic processGO:0051246560.015
protein complex biogenesisGO:0070271300.015
negative regulation of transcription dna templatedGO:0045892450.015
epithelial tube morphogenesisGO:00605621480.015
regulation of cell projection organizationGO:0031344440.015
negative regulation of macromolecule metabolic processGO:0010605760.015
regulation of wound healingGO:006104120.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
multi organism cellular processGO:004476420.015
neurotransmitter transportGO:000683620.015
adenohypophysis developmentGO:0021984150.015
establishment of protein localization to organelleGO:007259440.015
cell matrix adhesionGO:000716040.015
stem cell proliferationGO:007208940.015
macromolecular complex subunit organizationGO:0043933740.015
inner ear morphogenesisGO:0042472630.014
protein metabolic processGO:00195381830.014
behaviorGO:0007610740.014
mononuclear cell proliferationGO:003294310.014
cellular amine metabolic processGO:004410620.014
cellular amino acid metabolic processGO:000652070.014
epithelial cell developmentGO:0002064420.014
negative regulation of response to stimulusGO:00485851040.014
positive regulation of transcription dna templatedGO:0045893570.014
cellular response to fibroblast growth factor stimulusGO:0044344220.014
Zebrafish
sulfur compound metabolic processGO:0006790130.014
hormone transportGO:000991420.014
reproductive processGO:0022414400.014
branching morphogenesis of a nerveGO:004875540.014
mesoderm developmentGO:0007498880.014
positive regulation of cellular protein metabolic processGO:0032270220.014
convergent extensionGO:00600261180.014
oligodendrocyte differentiationGO:0048709230.013
extracellular structure organizationGO:0043062270.013
carbohydrate derivative metabolic processGO:1901135610.013
somatic stem cell maintenanceGO:003501910.013
muscle cell fate determinationGO:000752110.013
neuron neuron synaptic transmissionGO:000727010.013
cellular component disassemblyGO:002241110.013
mechanoreceptor differentiationGO:0042490370.013
chondrocyte developmentGO:000206340.013
positive regulation of multi organism processGO:004390230.013
positive regulation of developmental processGO:0051094500.013
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.013
organonitrogen compound metabolic processGO:1901564740.013
negative regulation of protein kinase activityGO:000646940.013
small molecule catabolic processGO:004428230.013
regulation of developmental growthGO:0048638380.013
neural crest cell differentiationGO:0014033720.013
peptide transportGO:001583310.013
microtubule depolymerizationGO:000701910.013
positive regulation of signalingGO:0023056560.012
Zebrafish
lateral line developmentGO:0048882660.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
angiogenesisGO:00015251580.012
cortical cytoskeleton organizationGO:003086510.012
regulation of protein import into nucleusGO:004230620.012
regulation of skeletal muscle tissue developmentGO:004864140.012
rho protein signal transductionGO:000726650.012
cellular macromolecular complex assemblyGO:0034622240.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of cellular protein metabolic processGO:0032268520.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
heart loopingGO:0001947940.012
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.012
Zebrafish
negative regulation of protein phosphorylationGO:000193340.012
negative regulation of developmental growthGO:004864090.012
lymphocyte proliferationGO:004665110.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
actin cytoskeleton organizationGO:0030036630.012
determination of left right symmetryGO:00073681790.012
regulation of gastrulationGO:0010470240.012
response to nutrientGO:000758430.012
protein localization to nucleusGO:003450430.012
central nervous system neuron developmentGO:0021954290.011
oxidoreduction coenzyme metabolic processGO:000673310.011
cellular respirationGO:004533330.011
negative regulation of mapk cascadeGO:004340940.011
golgi vesicle transportGO:004819330.011
nitric oxide metabolic processGO:004620920.011
renal system processGO:0003014140.011
locus ceruleus developmentGO:002170330.011
myofibril assemblyGO:0030239480.011
intracellular signal transductionGO:0035556850.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
protein import into nucleusGO:000660630.011
cellular response to biotic stimulusGO:007121630.011
lamellipodium organizationGO:009758110.011
cellular response to endogenous stimulusGO:0071495680.011
Zebrafish
positive regulation of wound healingGO:009030310.011
regulation of smoothened signaling pathwayGO:0008589180.011
ras protein signal transductionGO:000726570.011
response to alcoholGO:0097305140.011
gtp catabolic processGO:000618420.011
b cell activationGO:004211320.011
positive regulation of cell cycleGO:004578730.011
cellular response to decreased oxygen levelsGO:003629410.011
immunoglobulin mediated immune responseGO:001606430.011
negative regulation of multi organism processGO:004390130.011
regulation of reproductive processGO:200024140.010
type b pancreatic cell developmentGO:000332340.010
diencephalon developmentGO:0021536580.010
negative regulation of epithelial cell differentiationGO:003085720.010
developmental cell growthGO:0048588520.010
vasculature developmentGO:00019442780.010
macromolecular complex assemblyGO:0065003350.010
astrocyte differentiationGO:004870810.010
negative regulation of map kinase activityGO:004340720.010
deathGO:00162651210.010
regulation of cellular amino acid metabolic processGO:000652100.010
regulation of growthGO:0040008420.010

sp8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.081
disease of anatomical entityDOID:700.081
musculoskeletal system diseaseDOID:1700.050
connective tissue diseaseDOID:6500.050
sensory system diseaseDOID:005015500.032
eye diseaseDOID:561400.032
eye and adnexa diseaseDOID:149200.032
physical disorderDOID:008001500.015
disease of metabolismDOID:001466700.012