Danio rerio

0 known processes

plk2a

polo-like kinase 2a (Drosophila)

(Aliases: im:7157189)

plk2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell substrate adhesionGO:003158940.113
digestive system developmentGO:00551232890.103
blood vessel developmentGO:00015682460.102
morphogenesis of an epitheliumGO:00020093330.082
cellular nitrogen compound metabolic processGO:00346412900.081
sprouting angiogenesisGO:0002040530.081
angiogenesisGO:00015251580.074
blood vessel morphogenesisGO:00485142160.061
vasculature developmentGO:00019442780.060
digestive tract developmentGO:00485652650.055
agingGO:000756820.050
embryonic organ developmentGO:00485683810.046
immune system processGO:00023762410.045
meiotic nuclear divisionGO:000712640.045
meiotic cell cycle processGO:190304630.045
regulation of synapse organizationGO:005080730.043
stem cell maintenanceGO:001982740.043
larval developmentGO:000216420.043
synaptic growth at neuromuscular junctionGO:005112420.041
maintenance of locationGO:005123540.040
signal transductionGO:00071654550.040
response to drugGO:004249330.038
mitochondrion organizationGO:000700540.038
phagocytosisGO:000690930.037
cellular macromolecule metabolic processGO:00442603910.037
embryonic organ morphogenesisGO:00485622740.037
heterocycle metabolic processGO:00464832900.036
regulation of macromolecule metabolic processGO:00602553170.036
chordate embryonic developmentGO:00430092710.035
peptidyl serine modificationGO:001820920.035
cell motilityGO:00488702440.035
regulation of cellular metabolic processGO:00313233200.035
single organism metabolic processGO:00447102170.035
cellular amine metabolic processGO:004410620.035
guanosine containing compound catabolic processGO:190106920.034
response to external stimulusGO:00096052640.034
positive regulation of catabolic processGO:000989640.034
adherens junction organizationGO:003433240.033
organelle organizationGO:00069962270.033
lipid storageGO:001991510.033
cellular response to external stimulusGO:007149620.033
stem cell proliferationGO:007208940.032
regulation of metabolic processGO:00192223590.032
protein metabolic processGO:00195381830.032
regulation of signal transductionGO:00099662250.032
protein localization to plasma membraneGO:007265910.031
cellular component biogenesisGO:00440851780.031
localization of cellGO:00516742440.031
cell migrationGO:00164772370.031
proteolysis involved in cellular protein catabolic processGO:005160330.031
nucleic acid metabolic processGO:00903042440.031
cellular response to extracellular stimulusGO:003166820.031
regulation of response to stimulusGO:00485832690.031
nitrogen compound metabolic processGO:00068073190.031
cell matrix adhesionGO:000716040.031
regulation of cell shapeGO:000836010.031
cellular protein catabolic processGO:004425740.030
post embryonic organ developmentGO:004856940.030
regulation of cellular amine metabolic processGO:003323800.030
gtp metabolic processGO:004603940.030
guanosine containing compound metabolic processGO:190106840.030
regulation of cellular amino acid metabolic processGO:000652100.029
heart developmentGO:00075073130.029
gtp catabolic processGO:000618420.029
muscle cell developmentGO:00550011150.029
cellular aromatic compound metabolic processGO:00067252950.029
cognitionGO:005089010.029
positive regulation of cytokine productionGO:000181920.028
sensory organ developmentGO:00074233930.028
cellular response to starvationGO:000926710.028
cellular response to nutrient levelsGO:003166920.028
positive regulation of cellular component biogenesisGO:004408930.028
organic acid metabolic processGO:0006082310.028
protein localization to nucleusGO:003450430.026
ubiquitin dependent protein catabolic processGO:000651130.026
regulation of cellular ketone metabolic processGO:001056570.026
cellular ketone metabolic processGO:0042180110.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
positive regulation of transportGO:005105020.026
multicellular organismal metabolic processGO:004423620.026
neuroblast proliferationGO:000740520.025
organic cyclic compound metabolic processGO:19013603010.025
modification dependent protein catabolic processGO:001994130.025
germ line stem cell maintenanceGO:003071820.025
organic substance biosynthetic processGO:19015762890.024
response to nutrientGO:000758430.024
regulation of cell substrate adhesionGO:001081010.024
nucleocytoplasmic transportGO:000691340.024
negative regulation of protein kinase activityGO:000646940.024
regulation of metal ion transportGO:001095940.024
single organism nuclear importGO:190259330.024
peptidyl serine phosphorylationGO:001810510.024
positive regulation of cell adhesionGO:004578510.024
cellular component assemblyGO:00226071700.024
negative regulation of protein phosphorylationGO:000193340.024
tube morphogenesisGO:00352393490.024
meiotic chromosome segregationGO:004513230.023
cellular amino acid metabolic processGO:000652070.023
positive regulation of cellular catabolic processGO:003133130.023
regulation of intracellular protein transportGO:003315730.023
regulation of cytokine productionGO:000181730.023
oxoacid metabolic processGO:0043436310.023
skeletal muscle organ developmentGO:0060538780.023
regulation of cellular biosynthetic processGO:00313262450.023
specification of symmetryGO:00097992040.023
protein importGO:001703830.023
regulation of protein transportGO:005122330.023
stem cell differentiationGO:00488631170.023
gastrulationGO:00073692080.023
proteasomal protein catabolic processGO:001049820.023
modification dependent macromolecule catabolic processGO:004363230.023
regulation of cytoplasmic transportGO:190364940.023
endosomal transportGO:001619720.023
response to chemicalGO:00422213200.022
cellular component movementGO:00069283350.022
organelle assemblyGO:00709251100.022
small molecule metabolic processGO:0044281770.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
nucleobase containing compound metabolic processGO:00061392740.022
cellular lipid catabolic processGO:004424230.022
cellular response to hypoxiaGO:007145610.022
regulation of protein import into nucleusGO:004230620.022
cellular response to oxygen levelsGO:007145310.022
rna metabolic processGO:00160702190.022
carboxylic acid metabolic processGO:0019752220.022
regulation of establishment of protein localizationGO:007020140.022
digestive tract morphogenesisGO:00485462310.022
positive regulation of apoptotic signaling pathwayGO:200123510.021
regulation of cell activationGO:005086510.021
single organism organelle organizationGO:19025891990.021
regulation of protein localization to nucleusGO:190018020.021
negative regulation of cellular processGO:00485232830.021
ameboidal type cell migrationGO:00016671430.021
regulation of multicellular organism growthGO:004001440.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
regulation of nitrogen compound metabolic processGO:00511712510.021
phosphate containing compound metabolic processGO:00067961080.021
regulation of neural precursor cell proliferationGO:200017730.021
developmental growthGO:00485891660.021
autophagyGO:000691440.020
negative regulation of kinase activityGO:003367340.020
meiosis iGO:000712710.020
regulation of bindingGO:005109830.020
embryonic skeletal system developmentGO:0048706970.020
positive regulation of protein complex assemblyGO:003133420.020
cell projection morphogenesisGO:00488582440.020
erk1 and erk2 cascadeGO:007037140.020
cytokinesisGO:000091030.020
camera type eye developmentGO:00430102220.020
spindle assemblyGO:005122520.020
regulation of protein catabolic processGO:004217610.020
amine metabolic processGO:000930820.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
membrane invaginationGO:001032410.019
mesenchyme developmentGO:00604851270.019
protein import into nucleusGO:000660630.019
regulation of cellular component movementGO:0051270550.019
establishment of localizationGO:00512342440.019
regulation of nucleocytoplasmic transportGO:004682220.019
positive regulation of cellular processGO:00485222010.019
cell morphogenesisGO:00009022890.019
regulation of protein targetingGO:190353320.019
nuclear transportGO:005116940.019
membrane fusionGO:006102520.019
regulation of nucleoside metabolic processGO:000911820.019
regulation of endothelial cell proliferationGO:000193610.019
g1 s transition of mitotic cell cycleGO:000008210.019
regulation of synapse assemblyGO:005196330.019
locomotor rhythmGO:004547530.018
convergent extensionGO:00600261180.018
positive regulation of biological processGO:00485182530.018
regulation of erk1 and erk2 cascadeGO:007037240.018
positive regulation of nucleotide catabolic processGO:003081310.018
regulation of reactive oxygen species metabolic processGO:200037720.018
organelle fusionGO:004828430.018
positive regulation of epithelial cell migrationGO:001063420.018
lipid catabolic processGO:001604240.018
regulation of biosynthetic processGO:00098892500.018
regulation of multicellular organismal developmentGO:20000262230.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
positive regulation of nucleoside metabolic processGO:004597910.018
positive regulation of cellular amine metabolic processGO:003324000.018
cellular biosynthetic processGO:00442492860.018
regulation of primary metabolic processGO:00800903110.018
protein targeting to nucleusGO:004474430.018
organonitrogen compound metabolic processGO:1901564740.018
establishment of protein localization to organelleGO:007259440.018
multicellular organism growthGO:003526440.018
lateral inhibitionGO:004633110.017
cellular component disassemblyGO:002241110.017
determination of bilateral symmetryGO:00098552040.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
response to stressGO:00069502630.017
positive regulation of gtp catabolic processGO:003312610.017
regulation of nucleotide catabolic processGO:003081120.017
negative regulation of signalingGO:0023057960.017
generation of neuronsGO:00486993850.017
nuclear importGO:005117030.017
leukocyte mediated cytotoxicityGO:000190910.017
secondary metabolic processGO:001974830.017
positive regulation of cell cycleGO:004578730.017
negative regulation of cytoplasmic transportGO:190365020.017
protein dephosphorylationGO:000647030.017
rna localizationGO:000640340.017
phagocytosis engulfmentGO:000691110.017
regulation of cell deathGO:00109411030.017
positive regulation of cell activationGO:005086710.016
regulation of cell matrix adhesionGO:000195210.016
negative regulation of ras protein signal transductionGO:004658010.016
single organism localizationGO:19025782250.016
regulation of synaptic plasticityGO:004816710.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
tissue remodelingGO:004877140.016
locomotionGO:00400113130.016
positive regulation of jnk cascadeGO:004633030.016
response to glucoseGO:000974930.016
regulation of stem cell proliferationGO:007209120.016
single organism membrane fusionGO:004480120.016
cell substrate junction assemblyGO:000704420.016
cellular response to decreased oxygen levelsGO:003629410.016
calcium ion transport into cytosolGO:006040230.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
cell cycle g1 s phase transitionGO:004484310.016
positive regulation of gtpase activityGO:004354710.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
cytoskeleton organizationGO:0007010960.015
determination of left right symmetryGO:00073681790.015
regulation of protein complex assemblyGO:004325430.015
regulation of programmed cell deathGO:00430671010.015
regulation of purine nucleotide catabolic processGO:003312120.015
protein acetylationGO:000647320.015
axonogenesisGO:00074091520.015
macromolecule modificationGO:00434121110.015
regulation of mrna processingGO:005068430.015
regulation of rna biosynthetic processGO:20011412130.015
regulation of multicellular organismal metabolic processGO:004424620.015
regulation of reproductive processGO:200024140.015
cellular protein modification processGO:00064641000.015
response to corticosteroidGO:003196010.015
macromolecule biosynthetic processGO:00090592270.015
head developmentGO:00603223030.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
regulation of gtp catabolic processGO:003312420.015
positive regulation of stress activated mapk cascadeGO:003287430.015
eye morphogenesisGO:00485921440.015
mitotic cell cycleGO:0000278640.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
regulation of dendrite morphogenesisGO:004881430.015
positive regulation of cytoskeleton organizationGO:005149530.015
mitochondrion morphogenesisGO:007058420.014
maternal determination of anterior posterior axis embryoGO:000835840.014
regulation of localizationGO:00328791040.014
muscle structure developmentGO:00610611960.014
protein modification processGO:00362111000.014
negative regulation of nuclear divisionGO:005178430.014
regulation of cellular protein catabolic processGO:190336210.014
cellular localizationGO:0051641970.014
lymphocyte proliferationGO:004665110.014
sensory perception of smellGO:000760820.014
organic acid catabolic processGO:001605430.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
cell migration involved in gastrulationGO:0042074790.014
biosynthetic processGO:00090582940.014
regulation of autophagyGO:001050630.014
nucleic acid templated transcriptionGO:00976591810.014
negative regulation of response to stimulusGO:00485851040.014
negative regulation of catabolic processGO:000989530.014
convergent extension involved in gastrulationGO:0060027710.014
sensory perception of chemical stimulusGO:000760630.014
regulation of gtpase activityGO:004308720.014
protein complex assemblyGO:0006461300.014
embryo development ending in birth or egg hatchingGO:00097922710.014
actin polymerization or depolymerizationGO:000815420.014
peptidyl lysine acetylationGO:001839420.014
regulation of wound healingGO:006104120.013
response to hexoseGO:000974630.013
internal protein amino acid acetylationGO:000647520.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
adult behaviorGO:003053420.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
response to uvGO:000941130.013
cell part morphogenesisGO:00329902460.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
phosphorylationGO:0016310690.013
immune system developmentGO:00025201910.013
muscle fiber developmentGO:0048747520.013
response to monosaccharideGO:003428430.013
aromatic compound biosynthetic processGO:00194382170.013
regulation of multicellular organismal processGO:00512392770.013
striated muscle cell developmentGO:00550021080.013
interspecies interaction between organismsGO:004441940.013
establishment of protein localization to plasma membraneGO:009000210.013
mesenchymal cell differentiationGO:0048762870.013
organic cyclic compound biosynthetic processGO:19013622230.013
multicellular organismal macromolecule metabolic processGO:004425920.013
negative regulation of cellular catabolic processGO:003133030.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
negative regulation of map kinase activityGO:004340720.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
protein acylationGO:004354330.013
regulation of meiotic cell cycleGO:005144510.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
response to carbohydrateGO:000974330.012
regulation of dendrite developmentGO:005077330.012
neural crest cell developmentGO:0014032620.012
negative regulation of intracellular transportGO:003238730.012
system processGO:00030081850.012
muscle organ developmentGO:00075171010.012
cell cycleGO:0007049930.012
positive regulation of chromatin modificationGO:190331010.012
negative regulation of small gtpase mediated signal transductionGO:005105810.012
protein heterooligomerizationGO:005129110.012
peptidyl threonine phosphorylationGO:001810710.012
positive regulation of response to stimulusGO:0048584800.012
cellular component morphogenesisGO:00329893360.012
regulation of signalingGO:00230512350.012
single organism transportGO:00447652060.012
microtubule based processGO:0007017600.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
positive regulation of secretionGO:005104710.012
small molecule catabolic processGO:004428230.012
negative regulation of protein transportGO:005122430.012
regulation of gene expressionGO:00104682650.012
negative regulation of biological processGO:00485193040.012
atp catabolic processGO:000620040.012
positive regulation of stem cell proliferationGO:200064810.012
cell surface receptor signaling pathwayGO:00071663250.012
regulation of transporter activityGO:003240920.012
developmental programmed cell deathGO:001062340.012
epithelial cell differentiationGO:00308551160.012
cytoplasm organizationGO:000702840.012
growthGO:00400071740.012
exocytosisGO:000688710.012
regulation of macromolecule biosynthetic processGO:00105562250.012
fatty acid catabolic processGO:000906210.012
peptide transportGO:001583310.012
eye developmentGO:00016542770.012
cellular component maintenanceGO:004395430.012
regulation of dna replicationGO:000627530.012
fertilizationGO:000956630.012
homeostatic processGO:00425921420.012
regulation of cell projection assemblyGO:006049140.012
internal peptidyl lysine acetylationGO:001839320.012
cellular macromolecule biosynthetic processGO:00346452240.012
gene expressionGO:00104672520.012
macromolecule localizationGO:0033036540.012
axon developmentGO:00615641660.011
deathGO:00162651210.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
wnt signaling pathwayGO:0016055800.011
lipid oxidationGO:003444010.011
negative regulation of protein localization to nucleusGO:190018120.011
neuron neuron synaptic transmissionGO:000727010.011
response to glucocorticoidGO:005138410.011
protein polymerizationGO:005125840.011
cell projection assemblyGO:0030031640.011
cellular response to radiationGO:007147840.011
xenobiotic metabolic processGO:000680540.011
protein phosphorylationGO:0006468470.011
regulation of receptor mediated endocytosisGO:004825940.011
regulation of calcium ion transportGO:005192420.011
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
rna biosynthetic processGO:00327741810.011
neurotransmitter secretionGO:000726920.011
regulation of rho protein signal transductionGO:003502320.011
positive regulation of synapse assemblyGO:005196510.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
cell adhesionGO:0007155400.011
negative regulation of tor signalingGO:003200720.011
alcohol biosynthetic processGO:004616520.011
somite developmentGO:0061053960.011
positive regulation of epithelial cell proliferationGO:005067910.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
response to biotic stimulusGO:0009607970.011
negative regulation of mapk cascadeGO:004340940.011
positive regulation of dna metabolic processGO:005105410.011
positive regulation of map kinase activityGO:004340630.011
startle responseGO:000196440.011
positive regulation of immune effector processGO:000269930.011
sensory perception of painGO:001923310.011
neural crest cell differentiationGO:0014033720.011
transcription dna templatedGO:00063511810.011
protein homooligomerizationGO:005126030.011
apoptotic processGO:00069151160.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
developmental growth involved in morphogenesisGO:0060560860.011
wound healingGO:0042060900.011
regulation of fatty acid metabolic processGO:001921710.011
stem cell divisionGO:001714510.011
centrosome organizationGO:005129710.011
macroautophagyGO:001623610.011
chemosensory behaviorGO:000763510.011
epithelial tube morphogenesisGO:00605621480.011
intracellular signal transductionGO:0035556850.011
regulation of stem cell differentiationGO:200073640.011
cell deathGO:00082191210.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
cytosolic calcium ion transportGO:006040130.011
cellular amide metabolic processGO:004360340.010
cell morphogenesis involved in differentiationGO:00009041950.010
response to vitaminGO:003327330.010
monocarboxylic acid catabolic processGO:007232930.010
positive regulation of secretion by cellGO:190353210.010
peptidyl threonine modificationGO:001821010.010
lipid homeostasisGO:005508830.010
determination of heart left right asymmetryGO:00613711170.010
negative regulation of multi organism processGO:004390130.010
regulation of apoptotic processGO:0042981980.010
regulation of inflammatory responseGO:005072720.010
multi organism processGO:00517041340.010
cellular carbohydrate metabolic processGO:004426240.010
cellular protein metabolic processGO:00442671290.010
negative regulation of mitosisGO:004583930.010
regulation of protein polymerizationGO:003227120.010
transportGO:00068102200.010
cell junction maintenanceGO:003433120.010
retina development in camera type eyeGO:00600411460.010
anterior posterior pattern specificationGO:00099521520.010
microtubule organizing center organizationGO:003102310.010

plk2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
immune system diseaseDOID:291400.017
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.017
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.012
cardiovascular system diseaseDOID:128700.010