Danio rerio

28 known processes

tab2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

(Aliases: map3k7ip2,zgc:77446)

tab2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.168
agingGO:000756820.167
protein import into nucleusGO:000660630.152
establishment of protein localization to organelleGO:007259440.133
heart developmentGO:00075073130.129
single organism nuclear importGO:190259330.114
cognitionGO:005089010.108
nucleocytoplasmic transportGO:000691340.100
protein localization to nucleusGO:003450430.096
protein targeting to nucleusGO:004474430.093
nuclear importGO:005117030.084
positive regulation of cellular component biogenesisGO:004408930.083
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.080
vasculature developmentGO:00019442780.072
determination of bilateral symmetryGO:00098552040.071
regulation of response to nutrient levelsGO:003210710.071
cartilage developmentGO:0051216960.070
blood vessel developmentGO:00015682460.069
phagocytosisGO:000690930.069
positive regulation of transportGO:005105020.068
neuron differentiationGO:00301823530.067
nuclear transportGO:005116940.067
larval developmentGO:000216420.065
protein importGO:001703830.065
regulation of protein transportGO:005122330.064
single organism organelle organizationGO:19025891990.063
single organism transportGO:00447652060.061
single organism localizationGO:19025782250.061
regulation of extrinsic apoptotic signaling pathwayGO:200123630.060
regulation of multicellular organism growthGO:004001440.058
regulation of cell communicationGO:00106462320.055
skeletal system developmentGO:00015011810.055
cellular component movementGO:00069283350.055
blood vessel morphogenesisGO:00485142160.054
organelle organizationGO:00069962270.051
stem cell maintenanceGO:001982740.051
generation of neuronsGO:00486993850.051
regulation of stem cell differentiationGO:200073640.051
lipid homeostasisGO:005508830.050
signal transductionGO:00071654550.050
response to nutrientGO:000758430.050
stem cell proliferationGO:007208940.049
regulation of nucleocytoplasmic transportGO:004682220.048
meiotic cell cycle processGO:190304630.048
cellular response to nutrient levelsGO:003166920.048
positive regulation of biological processGO:00485182530.047
brain developmentGO:00074202930.046
transportGO:00068102200.046
hematopoietic or lymphoid organ developmentGO:00485341910.045
morphogenesis of an epitheliumGO:00020093330.044
connective tissue developmentGO:0061448990.044
cellular macromolecule metabolic processGO:00442603910.043
regulation of synaptic growth at neuromuscular junctionGO:000858210.043
regulation of cytoplasmic transportGO:190364940.043
chemosensory behaviorGO:000763510.043
response to chemicalGO:00422213200.042
regionalizationGO:00030022740.042
regulation of synapse assemblyGO:005196330.042
establishment of localizationGO:00512342440.042
sensory organ developmentGO:00074233930.042
cytoskeleton organizationGO:0007010960.042
localization of cellGO:00516742440.042
regulation of establishment of protein localizationGO:007020140.041
immune system processGO:00023762410.041
embryonic heart tube morphogenesisGO:00031431080.039
response to vitaminGO:003327330.038
tissue remodelingGO:004877140.038
cellular protein catabolic processGO:004425740.038
meiotic nuclear divisionGO:000712640.037
multicellular organism growthGO:003526440.036
modification dependent protein catabolic processGO:001994130.036
negative regulation of epithelial cell proliferationGO:005068010.035
regulation of protein targetingGO:190353320.035
eye developmentGO:00016542770.035
determination of left right symmetryGO:00073681790.035
regulation of reproductive processGO:200024140.034
adherens junction organizationGO:003433240.033
cellular response to extracellular stimulusGO:003166820.033
homeostatic processGO:00425921420.033
regulation of synapse organizationGO:005080730.033
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.033
regulation of stem cell proliferationGO:007209120.033
embryonic organ morphogenesisGO:00485622740.032
amino acid transportGO:000686520.032
germ line stem cell divisionGO:004207810.032
positive regulation of cellular processGO:00485222010.032
spindle assemblyGO:005122520.031
negative regulation of protein kinase activityGO:000646940.031
regulation of dna templated transcription elongationGO:003278430.031
growthGO:00400071740.031
lymph vessel developmentGO:0001945270.031
central nervous system developmentGO:00074173870.030
synaptic growth at neuromuscular junctionGO:005112420.030
regulation of protein complex assemblyGO:004325430.030
somitogenesisGO:0001756870.029
regulation of protein localization to nucleusGO:190018020.029
ubiquitin dependent protein catabolic processGO:000651130.029
regulation of protein import into nucleusGO:004230620.029
positive regulation of cytosolic calcium ion concentrationGO:000720440.029
segmentationGO:0035282970.029
skeletal system morphogenesisGO:00487051020.028
axon developmentGO:00615641660.028
regulation of localizationGO:00328791040.028
anterior posterior pattern specificationGO:00099521520.028
regulation of biological qualityGO:00650082630.028
maintenance of locationGO:005123540.028
autophagyGO:000691440.028
cellular component biogenesisGO:00440851780.027
heterocycle metabolic processGO:00464832900.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
negative regulation of protein phosphorylationGO:000193340.027
positive regulation of stem cell proliferationGO:200064810.027
primitive hemopoiesisGO:0060215270.027
regulation of metabolic processGO:00192223590.027
developmental growthGO:00485891660.027
regulation of protein catabolic processGO:004217610.027
actin polymerization or depolymerizationGO:000815420.026
negative regulation of biological processGO:00485193040.026
regulation of signalingGO:00230512350.026
cellular response to external stimulusGO:007149620.026
transcription elongation from rna polymerase ii promoterGO:000636830.026
positive regulation of cytoskeleton organizationGO:005149530.026
gastrulationGO:00073692080.026
cortical actin cytoskeleton organizationGO:003086610.026
regulation of multicellular organismal processGO:00512392770.026
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.026
somite developmentGO:0061053960.026
actin filament based movementGO:003004810.025
cell surface receptor signaling pathwayGO:00071663250.025
heart loopingGO:0001947940.025
somatic stem cell maintenanceGO:003501910.025
epithelial tube morphogenesisGO:00605621480.025
negative regulation of ras protein signal transductionGO:004658010.025
regulation of tube sizeGO:003515020.025
regulation of cell shapeGO:000836010.025
transcription from rna polymerase ii promoterGO:0006366800.025
dna templated transcription elongationGO:000635430.025
head developmentGO:00603223030.024
regulation of cellular metabolic processGO:00313233200.024
cellular component assemblyGO:00226071700.024
negative regulation of protein serine threonine kinase activityGO:007190120.024
embryonic hemopoiesisGO:0035162530.024
regulation of gene expressionGO:00104682650.024
angiogenesisGO:00015251580.024
immune system developmentGO:00025201910.024
female gonad developmentGO:000858540.023
negative regulation of chemotaxisGO:005092240.023
regulation of response to extracellular stimulusGO:003210410.023
modification dependent macromolecule catabolic processGO:004363230.022
regulation of intracellular protein transportGO:003315730.022
regulation of neural precursor cell proliferationGO:200017730.022
heterocycle biosynthetic processGO:00181302150.022
regulation of cell matrix adhesionGO:000195210.021
adult behaviorGO:003053420.021
positive regulation of cellular catabolic processGO:003133130.021
chordate embryonic developmentGO:00430092710.021
meiosis iGO:000712710.021
germ line stem cell maintenanceGO:003071820.021
meiotic spindle organizationGO:000021210.021
chemical homeostasisGO:0048878490.021
deathGO:00162651210.020
organic cyclic compound metabolic processGO:19013603010.020
regulation of dna recombinationGO:000001820.020
embryonic heart tube developmentGO:00350501330.020
regulation of response to stimulusGO:00485832690.020
erk1 and erk2 cascadeGO:007037140.020
microtubule cytoskeleton organization involved in mitosisGO:190285010.020
nucleobase containing compound biosynthetic processGO:00346542050.020
sequestering of calcium ionGO:005120830.020
regulation of epithelial cell proliferationGO:005067830.020
cell substrate adhesionGO:003158940.020
extrinsic apoptotic signaling pathwayGO:009719130.020
glial cell proliferationGO:001400940.019
response to metal ionGO:0010038340.019
alpha amino acid metabolic processGO:190160530.019
hypothalamus cell differentiationGO:002197940.019
regulation of erk1 and erk2 cascadeGO:007037240.019
cardiac atrium developmentGO:000323040.019
nitrogen compound metabolic processGO:00068073190.019
actin filament based processGO:0030029640.019
regulation of synaptic plasticityGO:004816710.019
hepaticobiliary system developmentGO:0061008980.019
response to ketoneGO:190165410.019
carboxylic acid metabolic processGO:0019752220.019
endosomal transportGO:001619720.019
b cell activationGO:004211320.019
neurotransmitter transportGO:000683620.019
cellular nitrogen compound metabolic processGO:00346412900.019
negative regulation of synapse assemblyGO:005196420.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
guanosine containing compound catabolic processGO:190106920.018
negative regulation of chromosome organizationGO:200125110.018
cell migrationGO:00164772370.018
hormone secretionGO:004687920.018
regulation of anatomical structure morphogenesisGO:00226031300.018
endosome organizationGO:000703220.018
regulation of cellular response to growth factor stimulusGO:0090287350.018
regulation of biosynthetic processGO:00098892500.018
cell morphogenesis involved in differentiationGO:00009041950.018
regulation of cell activationGO:005086510.018
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
cardiac cell fate commitmentGO:006091110.018
regulation of skeletal muscle tissue developmentGO:004864140.018
regulation of blood vessel sizeGO:005088020.018
pharyngeal muscle developmentGO:004328240.018
mesenchyme developmentGO:00604851270.018
behaviorGO:0007610740.017
lymphangiogenesisGO:0001946250.017
heart morphogenesisGO:00030071560.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
positive regulation of dna metabolic processGO:005105410.017
regulation of rna biosynthetic processGO:20011412130.017
peptidyl serine phosphorylationGO:001810510.017
negative regulation of neural precursor cell proliferationGO:200017810.017
regulation of cell substrate adhesionGO:001081010.017
lipid storageGO:001991510.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
microtubule organizing center organizationGO:003102310.017
regulation of macromolecule metabolic processGO:00602553170.017
phosphorylationGO:0016310690.017
regulation of autophagyGO:001050630.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
vasculogenesisGO:0001570410.017
organelle assemblyGO:00709251100.017
cellular amino acid metabolic processGO:000652070.017
locomotionGO:00400113130.017
tube morphogenesisGO:00352393490.017
negative regulation of mapk cascadeGO:004340940.016
transcription dna templatedGO:00063511810.016
monoamine transportGO:001584410.016
positive regulation of cell cycleGO:004578730.016
positive regulation of catabolic processGO:000989640.016
regulation of biomineral tissue developmentGO:007016720.016
regulation of meiotic cell cycleGO:005144510.016
neurotransmitter secretionGO:000726920.016
cell morphogenesisGO:00009022890.016
i kappab kinase nf kappab signalingGO:000724940.016
cell motilityGO:00488702440.016
epithelium migrationGO:0090132250.016
proteasomal protein catabolic processGO:001049820.016
negative regulation of sequestering of calcium ionGO:005128340.016
response to carbohydrateGO:000974330.016
rna biosynthetic processGO:00327741810.016
negative chemotaxisGO:005091910.016
immunoglobulin mediated immune responseGO:001606430.016
regulation of mesenchymal cell proliferationGO:001046410.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
peptidyl serine modificationGO:001820920.015
rna metabolic processGO:00160702190.015
negative regulation of stem cell differentiationGO:200073720.015
organic acid metabolic processGO:0006082310.015
negative regulation of kinase activityGO:003367340.015
compound eye developmentGO:004874920.015
chromosome organization involved in meiosisGO:007019210.015
regulation of myotube differentiationGO:001083020.015
cell matrix adhesionGO:000716040.015
synaptic vesicle localizationGO:009747910.015
cellular response to starvationGO:000926710.015
response to drugGO:004249330.015
regulation of fatty acid metabolic processGO:001921710.015
meiotic chromosome segregationGO:004513230.015
cellular macromolecule biosynthetic processGO:00346452240.015
cortical cytoskeleton organizationGO:003086510.015
stem cell divisionGO:001714510.015
regulation of cellular component organizationGO:0051128860.014
response to hexoseGO:000974630.014
central nervous system neuron differentiationGO:0021953740.014
cardiac atrium morphogenesisGO:000320920.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
cellular aromatic compound metabolic processGO:00067252950.014
negative regulation of reproductive processGO:200024230.014
regulation of organelle assemblyGO:190211540.014
digestive system developmentGO:00551232890.014
oxoacid metabolic processGO:0043436310.014
regulation of macromolecule biosynthetic processGO:00105562250.014
establishment of rna localizationGO:005123630.014
positive regulation of notch signaling pathwayGO:004574730.014
blood vessel endothelial cell migrationGO:0043534180.014
embryonic skeletal system developmentGO:0048706970.014
l amino acid transportGO:001580710.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
regulation of intracellular signal transductionGO:1902531570.014
positive regulation of secretionGO:005104710.014
neuroblast proliferationGO:000740520.014
protein acetylationGO:000647320.014
appendage developmentGO:0048736800.014
single organism intracellular transportGO:1902582250.014
metal ion homeostasisGO:0055065260.014
stem cell fate commitmentGO:004886510.014
regulation of system processGO:0044057400.014
epithelial cell morphogenesisGO:000338220.014
meiosis iiGO:000713510.014
organic substance transportGO:0071702580.014
actin cytoskeleton organizationGO:0030036630.014
response to monosaccharideGO:003428430.014
centrosome organizationGO:005129710.014
peptide transportGO:001583310.014
cell deathGO:00082191210.014
response to corticosteroidGO:003196010.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
establishment of synaptic vesicle localizationGO:009748010.014
erythrocyte homeostasisGO:0034101550.014
immunoglobulin productionGO:000237710.013
cellular response to light stimulusGO:007148240.013
positive regulation of mesenchymal cell proliferationGO:000205310.013
bmp signaling pathwayGO:0030509520.013
forebrain developmentGO:0030900960.013
lymph vessel morphogenesisGO:0036303250.013
dicarboxylic acid transportGO:000683510.013
actin mediated cell contractionGO:007025210.013
neuroblast differentiationGO:001401610.013
regulation of cellular amine metabolic processGO:003323800.013
lateral inhibitionGO:004633110.013
macroautophagyGO:001623610.013
production of molecular mediator of immune responseGO:000244020.013
axoneme assemblyGO:003508290.013
organic cyclic compound biosynthetic processGO:19013622230.013
cellular localizationGO:0051641970.013
regulation of developmental processGO:00507932470.013
regulation of chromosome segregationGO:005198310.013
b cell mediated immunityGO:001972430.013
single organism cellular localizationGO:1902580460.013
g protein coupled receptor signaling pathwayGO:0007186740.013
somatic cell dna recombinationGO:001644410.013
exocytosisGO:000688710.013
regulation of cell migrationGO:0030334400.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
ameboidal type cell migrationGO:00016671430.013
axonogenesisGO:00074091520.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
rna localizationGO:000640340.013
macromolecule modificationGO:00434121110.012
positive regulation of cell communicationGO:0010647560.012
pericardium morphogenesisGO:000334410.012
apoptotic processGO:00069151160.012
ion homeostasisGO:0050801410.012
regulation of oocyte developmentGO:006028130.012
regulation of dendrite morphogenesisGO:004881430.012
nucleic acid transportGO:005065720.012
cellular transition metal ion homeostasisGO:004691630.012
cellular response to oxygen levelsGO:007145310.012
convergent extension involved in gastrulationGO:0060027710.012
membrane fusionGO:006102520.012
positive regulation of neural precursor cell proliferationGO:200017910.012
negative regulation of signal transductionGO:0009968940.012
cell proliferationGO:0008283800.012
organelle fusionGO:004828430.012
post embryonic organ developmentGO:004856940.012
glial cell migrationGO:000834730.012
guanosine containing compound metabolic processGO:190106840.012
cellular response to chemical stimulusGO:00708871570.012
regulation of organ growthGO:004662030.012
organic substance biosynthetic processGO:19015762890.012
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of synapse assemblyGO:005196510.012
negative regulation of intracellular transportGO:003238730.012
positive regulation of secretion by cellGO:190353210.012
positive regulation of developmental processGO:0051094500.012
neurological system processGO:0050877620.012
regulation of developmental growthGO:0048638380.012
negative regulation of cellular processGO:00485232830.012
lymphatic endothelial cell differentiationGO:006083610.012
regulation of apoptotic processGO:0042981980.012
outflow tract morphogenesisGO:000315110.012
hemopoiesisGO:00300971830.011
calcium mediated signalingGO:001972220.011
cell projection morphogenesisGO:00488582440.011
multi organism processGO:00517041340.011
centrosome duplicationGO:005129810.011
positive regulation of chromosome organizationGO:200125210.011
cellular biosynthetic processGO:00442492860.011
internal protein amino acid acetylationGO:000647520.011
iron ion homeostasisGO:005507240.011
phosphorus metabolic processGO:00067931090.011
female sex differentiationGO:004666040.011
positive regulation of stress activated mapk cascadeGO:003287430.011
internal peptidyl lysine acetylationGO:001839320.011
female meiotic divisionGO:000714320.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
response to glucoseGO:000974930.011
determination of heart left right asymmetryGO:00613711170.011
regulation of receptor mediated endocytosisGO:004825940.011
fin developmentGO:0033333770.011
regulation of cellular protein catabolic processGO:190336210.011
mitotic nuclear divisionGO:0007067180.011
positive regulation of gtpase activityGO:004354710.011
synaptic target recognitionGO:000803910.011
regulation of catenin import into nucleusGO:003541220.011
regulation of cell deathGO:00109411030.011
establishment of localization in cellGO:0051649770.011
endothelial cell migrationGO:0043542190.011
intracellular transportGO:0046907320.011
positive regulation of jnk cascadeGO:004633030.011
endothelial cell fate commitmentGO:006083930.011
regulation of multicellular organismal developmentGO:20000262230.011
synaptic transmission cholinergicGO:000727140.011
pyruvate metabolic processGO:000609010.011
protein targeting to vacuoleGO:000662310.011
regulation of neurological system processGO:003164420.011
cellular modified amino acid metabolic processGO:000657530.011
regulation of neurotransmitter secretionGO:004692810.011
negative regulation of cellular catabolic processGO:003133030.011
wound healingGO:0042060900.011
synaptic vesicle transportGO:004848910.011
gene expressionGO:00104672520.011
embryonic skeletal system morphogenesisGO:0048704930.011
negative regulation of developmental processGO:0051093650.011
peptidyl lysine acetylationGO:001839420.011
cellular component morphogenesisGO:00329893360.011
regulation of cellular ketone metabolic processGO:001056570.011
septum transversum developmentGO:000334340.011
negative regulation of signalingGO:0023057960.011
specification of symmetryGO:00097992040.011
regulation of bmp signaling pathwayGO:0030510390.011
mitotic sister chromatid segregationGO:000007060.011
negative regulation of catabolic processGO:000989530.011
regulation of locomotionGO:0040012550.010
positive regulation of neuron deathGO:190121610.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.010
gtp metabolic processGO:004603940.010
cellular amine metabolic processGO:004410620.010
response to lipidGO:0033993600.010
activation of mapk activityGO:000018730.010
regulation of signal transductionGO:00099662250.010
positive regulation of cell activationGO:005086710.010
positive regulation of nucleoside metabolic processGO:004597910.010
tissue regenerationGO:0042246740.010
regulation of neuronal synaptic plasticityGO:004816810.010
adherens junction maintenanceGO:003433420.010
muscle cell differentiationGO:00426921390.010
cardiac conductionGO:006133730.010
regulation of protein bindingGO:004339330.010
direct ossificationGO:003607230.010
neuron developmentGO:00486662620.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.010
regulation of protein modification by small protein conjugation or removalGO:190332030.010
response to endogenous stimulusGO:0009719830.010
olfactory lobe developmentGO:002198840.010

tab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.054
disease of cellular proliferationDOID:1456600.035
organ system cancerDOID:005068600.031
cancerDOID:16200.031
musculoskeletal system diseaseDOID:1700.016
sensory system diseaseDOID:005015500.010
nervous system diseaseDOID:86300.010