Danio rerio

15 known processes

hsp90b1

heat shock protein 90, beta (grp94), member 1

(Aliases: tra-1,wu:fq25g01,GP96,GRP94,wu:fb61d09,tra1,fb61d09)

hsp90b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to topologically incorrect proteinGO:003596720.992
response to topologically incorrect proteinGO:003596620.966
endoplasmic reticulum unfolded protein responseGO:003096820.956
cellular response to unfolded proteinGO:003462020.910
er nucleus signaling pathwayGO:000698420.864
response to unfolded proteinGO:000698620.793
cellular component assemblyGO:00226071700.732
Human
larval developmentGO:000216420.669
Worm
response to endoplasmic reticulum stressGO:003497660.652
response to stressGO:00069502630.605
Human
cellular response to toxic substanceGO:009723710.565
regulation of multicellular organism growthGO:004001440.429
signal transductionGO:00071654550.416
embryonic organ developmentGO:00485683810.407
response to organic substanceGO:00100331530.385
Human
response to antibioticGO:004667710.352
response to abiotic stimulusGO:00096281220.351
Human
response to chemicalGO:00422213200.325
Human
multicellular organismal reproductive processGO:0048609350.296
brain developmentGO:00074202930.280
sensory organ developmentGO:00074233930.262
agingGO:000756820.256
macromolecule biosynthetic processGO:00090592270.254
cellular component biogenesisGO:00440851780.252
Human
proteolysis involved in cellular protein catabolic processGO:005160330.238
Human
response to temperature stimulusGO:0009266150.225
regulation of multicellular organismal processGO:00512392770.223
protein metabolic processGO:00195381830.215
Human
embryo development ending in birth or egg hatchingGO:00097922710.187
Worm
single organism organelle organizationGO:19025891990.171
Human
digestive system developmentGO:00551232890.170
Fly
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.165
cellular response to organic substanceGO:00713101050.162
Human
positive regulation of cellular processGO:00485222010.161
cellular response to chemical stimulusGO:00708871570.159
Human
cellular response to antibioticGO:007123610.138
multicellular organism growthGO:003526440.133
multicellular organism reproductionGO:0032504350.128
sexual reproductionGO:0019953360.127
organic cyclic compound metabolic processGO:19013603010.123
cell substrate junction assemblyGO:000704420.122
cellular protein metabolic processGO:00442671290.121
Human
regulation of response to stimulusGO:00485832690.121
system processGO:00030081850.115
cellular response to stressGO:0033554620.114
modification dependent macromolecule catabolic processGO:004363230.109
Human
modification dependent protein catabolic processGO:001994130.108
Human
cellular macromolecule metabolic processGO:00442603910.108
Human
heart developmentGO:00075073130.106
proteasomal protein catabolic processGO:001049820.105
Human
cell motilityGO:00488702440.104
locomotionGO:00400113130.103
Worm
regulation of extrinsic apoptotic signaling pathwayGO:200123630.102
gamete generationGO:0007276330.100
cellular protein catabolic processGO:004425740.098
Human
response to heatGO:000940860.098
anatomical structure arrangementGO:004853220.094
head developmentGO:00603223030.091
determination of bilateral symmetryGO:00098552040.088
cellular nitrogen compound metabolic processGO:00346412900.087
regulation of cell deathGO:00109411030.086
Human
embryonic organ morphogenesisGO:00485622740.084
maintenance of locationGO:005123540.083
Worm
cellular response to biotic stimulusGO:007121630.082
cellular biosynthetic processGO:00442492860.082
midbrain developmentGO:0030901280.081
transmembrane transportGO:00550851200.081
positive regulation of developmental processGO:0051094500.080
positive regulation of biological processGO:00485182530.079
apoptotic processGO:00069151160.077
Human
multicellular organismal homeostasisGO:0048871290.077
specification of symmetryGO:00097992040.077
cellular component morphogenesisGO:00329893360.076
reproductionGO:0000003400.075
Worm
biosynthetic processGO:00090582940.073
heart loopingGO:0001947940.072
cellular component movementGO:00069283350.072
purine nucleoside monophosphate catabolic processGO:000912840.071
negative regulation of biological processGO:00485193040.071
Human
cellular macromolecule biosynthetic processGO:00346452240.070
determination of left right symmetryGO:00073681790.069
sensory organ morphogenesisGO:00905962000.069
regulation of nuclease activityGO:003206910.068
cell proliferationGO:0008283800.067
regulation of apoptotic processGO:0042981980.066
Human
cellular localizationGO:0051641970.066
programmed cell deathGO:00125011190.065
Human
cellular response to nutrient levelsGO:003166920.065
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.064
Human
cell surface receptor signaling pathwayGO:00071663250.063
deathGO:00162651210.063
Human
developmental growthGO:00485891660.062
regulation of nucleobase containing compound metabolic processGO:00192192500.061
response to oxygen containing compoundGO:1901700550.061
Human
positive regulation of transportGO:005105020.061
embryonic heart tube morphogenesisGO:00031431080.059
response to biotic stimulusGO:0009607970.059
cytoskeleton organizationGO:0007010960.058
Human
establishment of protein localization to organelleGO:007259440.057
tube morphogenesisGO:00352393490.056
Fly
single organism reproductive processGO:0044702400.056
protein targeting to membraneGO:000661210.055
circulatory system processGO:0003013870.054
nucleoside monophosphate catabolic processGO:000912540.053
regulation of biological qualityGO:00650082630.051
Worm
morphogenesis of an epitheliumGO:00020093330.050
cell migrationGO:00164772370.050
protein n linked glycosylationGO:000648710.050
endosome organizationGO:000703220.049
regulation of metal ion transportGO:001095940.048
positive regulation of rna biosynthetic processGO:1902680570.048
regulation of developmental growthGO:0048638380.048
cell morphogenesisGO:00009022890.047
regulation of signal transductionGO:00099662250.047
cell junction organizationGO:0034330110.046
regulation of protein ubiquitinationGO:003139630.046
single organism localizationGO:19025782250.045
reproductive processGO:0022414400.045
cellular response to starvationGO:000926710.045
regulation of cellular biosynthetic processGO:00313262450.044
positive regulation of secretion by cellGO:190353210.044
organelle organizationGO:00069962270.044
Human
regulation of protein bindingGO:004339330.043
regulation of gene expressionGO:00104682650.043
regulation of establishment of protein localizationGO:007020140.042
central nervous system developmentGO:00074173870.042
organonitrogen compound metabolic processGO:1901564740.042
generation of neuronsGO:00486993850.042
negative regulation of apoptotic processGO:0043066550.041
Human
muscle cell developmentGO:00550011150.041
posterior lateral line neuromast developmentGO:0048919200.040
macromolecule modificationGO:00434121110.040
single organism metabolic processGO:00447102170.040
muscle cell differentiationGO:00426921390.040
ovulation cycle processGO:002260220.040
regulation of localizationGO:00328791040.039
pigmentationGO:0043473850.039
heart morphogenesisGO:00030071560.039
leukocyte proliferationGO:007066110.039
regulation of epithelial cell proliferationGO:005067830.038
regulation of blood pressureGO:000821710.038
neuron projection developmentGO:00311751800.038
otolith developmentGO:0048840320.038
kidney developmentGO:0001822920.038
nucleobase containing compound biosynthetic processGO:00346542050.038
developmental maturationGO:0021700340.037
carbohydrate derivative metabolic processGO:1901135610.036
regulation of biosynthetic processGO:00098892500.036
embryonic heart tube developmentGO:00350501330.036
cation transportGO:0006812810.036
single organism transportGO:00447652060.036
heart processGO:0003015710.035
dna catabolic processGO:000630810.035
regulation of nucleoside metabolic processGO:000911820.035
phosphate containing compound metabolic processGO:00067961080.035
Human
digestive tract developmentGO:00485652650.035
Fly
cellular modified amino acid metabolic processGO:000657530.035
cellular process involved in reproduction in multicellular organismGO:0022412280.034
catabolic processGO:0009056320.033
Human
nitrogen compound metabolic processGO:00068073190.033
cellular protein modification processGO:00064641000.033
rna metabolic processGO:00160702190.033
establishment of localizationGO:00512342440.032
Worm
purine ribonucleoside monophosphate catabolic processGO:000916940.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.032
positive regulation of multicellular organismal processGO:0051240520.032
epithelial tube morphogenesisGO:00605621480.032
regionalizationGO:00030022740.031
meiotic nuclear divisionGO:000712640.031
ovulation cycleGO:004269820.031
regulation of chromosome segregationGO:005198310.031
gastrulationGO:00073692080.031
oxoacid metabolic processGO:0043436310.031
response to decreased oxygen levelsGO:0036293250.030
Human
protein stabilizationGO:005082120.030
macromolecule catabolic processGO:0009057150.030
Human
positive regulation of apoptotic signaling pathwayGO:200123510.030
negative regulation of cellular processGO:00485232830.030
Human
growthGO:00400071740.030
skeletal system developmentGO:00015011810.030
transcription from rna polymerase ii promoterGO:0006366800.029
striated muscle cell differentiationGO:00511461290.029
multi organism processGO:00517041340.029
positive regulation of cytokine productionGO:000181920.029
negative regulation of cell deathGO:0060548600.028
Human
spermatogenesisGO:000728370.028
organic substance biosynthetic processGO:19015762890.028
cellular catabolic processGO:0044248270.028
Human
neurological system processGO:0050877620.027
developmental pigmentationGO:0048066480.027
regulation of erk1 and erk2 cascadeGO:007037240.027
posterior lateral line developmentGO:0048916380.027
cell deathGO:00082191210.027
Human
regulation of cell proliferationGO:0042127370.027
regulation of signalingGO:00230512350.027
peripheral nervous system neuron differentiationGO:0048934280.026
regulation of cytokine productionGO:000181730.026
double strand break repairGO:000630230.026
nucleobase containing compound metabolic processGO:00061392740.026
cellular response to external stimulusGO:007149620.026
ameboidal type cell migrationGO:00016671430.026
positive regulation of secretionGO:005104710.026
atp catabolic processGO:000620040.026
b cell activationGO:004211320.025
regulation of programmed cell deathGO:00430671010.025
Human
regulation of anatomical structure morphogenesisGO:00226031300.024
cellular response to endogenous stimulusGO:0071495680.024
Human
heterocycle biosynthetic processGO:00181302150.024
toxin transportGO:190199820.024
cellular aromatic compound metabolic processGO:00067252950.024
cellular response to steroid hormone stimulusGO:0071383310.024
blood circulationGO:0008015870.024
nuclear migrationGO:000709730.024
interaction with hostGO:005170140.023
regulation of transcription dna templatedGO:00063552130.023
female gonad developmentGO:000858540.023
regulation of macromolecule metabolic processGO:00602553170.023
neuron projection morphogenesisGO:00488121610.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
regulation of metabolic processGO:00192223590.023
Human
regulation of macromolecule biosynthetic processGO:00105562250.022
peptide metabolic processGO:000651810.022
regulation of growthGO:0040008420.022
renal system developmentGO:0072001940.022
glycosylationGO:0070085110.022
establishment of localization in cellGO:0051649770.022
response to hypoxiaGO:0001666250.022
Human
type i interferon productionGO:003260620.021
regulation of blood circulationGO:1903522320.021
protein dephosphorylationGO:000647030.021
formation of primary germ layerGO:0001704620.021
regulation of ion transportGO:0043269220.021
regulation of heart contractionGO:0008016320.021
regulation of synapse organizationGO:005080730.021
iron ion transmembrane transportGO:003475530.021
inner ear developmentGO:00488391260.021
ubiquitin dependent protein catabolic processGO:000651130.021
Human
exocytosisGO:000688710.021
nucleic acid templated transcriptionGO:00976591810.021
protein modification processGO:00362111000.020
ovarian follicle developmentGO:000154120.020
protein complex subunit organizationGO:0071822460.020
Human
erk1 and erk2 cascadeGO:007037140.020
regulation of nitrogen compound metabolic processGO:00511712510.020
fertilizationGO:000956630.020
regulation of systemic arterial blood pressureGO:000307310.020
germ cell developmentGO:0007281220.020
regulation of protein transportGO:005122330.020
regulation of protein modification by small protein conjugation or removalGO:190332030.019
organic cyclic compound biosynthetic processGO:19013622230.019
defense response to fungusGO:005083220.019
negative regulation of heart contractionGO:004582220.019
response to lipidGO:0033993600.019
exocrine system developmentGO:0035272280.018
regulation of developmental processGO:00507932470.018
cellular response to estrogen stimulusGO:0071391240.018
localization of cellGO:00516742440.018
ear morphogenesisGO:0042471640.018
muscle structure developmentGO:00610611960.018
response to external biotic stimulusGO:0043207970.018
spermatid developmentGO:000728620.018
fat soluble vitamin biosynthetic processGO:004236220.018
amine metabolic processGO:000930820.018
antimicrobial humoral responseGO:001973020.017
rna biosynthetic processGO:00327741810.017
regulation of cell activationGO:005086510.017
hemopoiesisGO:00300971830.017
gtp metabolic processGO:004603940.017
mitotic cell cycleGO:0000278640.017
cellular response to extracellular stimulusGO:003166820.017
cation transmembrane transportGO:0098655650.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
heterocycle metabolic processGO:00464832900.016
regulation of nucleotide catabolic processGO:003081120.016
neuron differentiationGO:00301823530.016
regulation of cellular metabolic processGO:00313233200.016
Human
organic substance catabolic processGO:1901575280.016
Human
single organism cellular localizationGO:1902580460.016
regulation of cell shapeGO:000836010.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
positive regulation of cell activationGO:005086710.016
protein importGO:001703830.016
retina homeostasisGO:0001895120.015
cellular response to lipidGO:0071396390.015
regulation of bindingGO:005109830.015
cellular response to molecule of bacterial originGO:007121930.015
embryonic skeletal system developmentGO:0048706970.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
regulation of neuron differentiationGO:0045664560.015
homeostatic processGO:00425921420.015
single fertilizationGO:000733830.015
heart contractionGO:0060047710.015
regulation of cytoplasmic transportGO:190364940.015
proteolysisGO:0006508380.015
Human
post embryonic developmentGO:000979170.014
Worm
inner ear receptor cell fate commitmentGO:006012040.014
gene expressionGO:00104672520.014
multi organism reproductive processGO:0044703360.014
skeletal muscle tissue developmentGO:0007519670.014
peripheral nervous system developmentGO:0007422550.014
negative regulation of gene expressionGO:0010629650.014
chordate embryonic developmentGO:00430092710.014
spindle assembly involved in mitosisGO:009030710.014
positive regulation of multi organism processGO:004390230.014
mononuclear cell proliferationGO:003294310.014
negative regulation of metabolic processGO:0009892860.014
cell cycleGO:0007049930.014
response to growth factorGO:0070848390.014
protein modification by small protein conjugationGO:0032446130.014
protein localization to membraneGO:007265790.014
meiotic cell cycle processGO:190304630.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
positive regulation of embryonic developmentGO:004001930.013
cytokinetic processGO:003250620.013
cell projection organizationGO:00300302840.013
production of molecular mediator of immune responseGO:000244020.013
regulation of rna biosynthetic processGO:20011412130.013
reactive oxygen species metabolic processGO:007259360.013
activation of mapk activityGO:000018730.013
chemosensory behaviorGO:000763510.013
regulation of protein catabolic processGO:004217610.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
anatomical structure homeostasisGO:0060249360.013
carboxylic acid metabolic processGO:0019752220.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
regulation of multicellular organismal developmentGO:20000262230.013
extrinsic apoptotic signaling pathwayGO:009719130.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
positive regulation of transcription dna templatedGO:0045893570.012
cell agingGO:000756920.012
inorganic ion transmembrane transportGO:0098660570.012
epithelial cell differentiationGO:00308551160.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
spermatid differentiationGO:004851520.012
mechanoreceptor differentiationGO:0042490370.012
cellular macromolecule catabolic processGO:0044265120.012
Human
regulation of ion transmembrane transporter activityGO:003241220.012
female meiotic divisionGO:000714320.012
cerebellar cortex developmentGO:002169550.012
neural nucleus developmentGO:0048857150.012
positive regulation of neuron deathGO:190121610.012
oocyte maturationGO:000155640.012
regulation of system processGO:0044057400.012
regulation of tube sizeGO:003515020.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
regulation of neurotransmitter secretionGO:004692810.012
establishment of protein localization to membraneGO:009015030.012
response to oxygen levelsGO:0070482250.012
Human
cellular amine metabolic processGO:004410620.012
negative regulation of macromolecule metabolic processGO:0010605760.012
negative regulation of macromolecule biosynthetic processGO:0010558480.011
b cell differentiationGO:003018310.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
development of primary female sexual characteristicsGO:004654540.011
phosphorus metabolic processGO:00067931090.011
Human
response to external stimulusGO:00096052640.011
small molecule metabolic processGO:0044281770.011
negative regulation of cellular metabolic processGO:0031324770.011
transportGO:00068102200.011
Worm
response to yeastGO:0001878230.011
regulation of cellular amine metabolic processGO:003323800.011
sensory system developmentGO:0048880760.011
mechanosensory lateral line system developmentGO:0048881490.011
neuronal action potentialGO:0019228180.011
positive regulation of catabolic processGO:000989640.011
positive regulation of tyrosine phosphorylation of stat proteinGO:004253110.011
negative regulation of blood circulationGO:190352320.011
regulation of transportGO:0051049450.011
positive regulation of cellular amine metabolic processGO:003324000.011
gland developmentGO:00487321430.011
metencephalon developmentGO:0022037270.011
positive regulation of cellular metabolic processGO:0031325940.011
response to ethanolGO:004547160.011
cellular sodium ion homeostasisGO:000688310.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
peptidyl serine modificationGO:001820920.010
regulation of purine nucleotide catabolic processGO:003312120.010
hemidesmosome assemblyGO:003158110.010
negative regulation of i kappab kinase nf kappab signalingGO:004312410.010
nucleocytoplasmic transportGO:000691340.010
aromatic compound biosynthetic processGO:00194382170.010
positive regulation of developmental growthGO:004863960.010
regulation of transmembrane transporter activityGO:002289820.010
response to estrogenGO:0043627270.010
muscle organ developmentGO:00075171010.010

hsp90b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.131
immune system diseaseDOID:291400.089
hematopoietic system diseaseDOID:7400.089
disease of cellular proliferationDOID:1456600.033
organ system cancerDOID:005068600.033
cancerDOID:16200.033
nervous system diseaseDOID:86300.033
musculoskeletal system diseaseDOID:1700.018
inherited metabolic disorderDOID:65500.013
lysosomal storage diseaseDOID:321100.013
disease of metabolismDOID:001466700.013
myopathyDOID:42300.013
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
connective tissue diseaseDOID:6500.012
endocrine system diseaseDOID:2800.011