Danio rerio

24 known processes

lats1

LATS, large tumor suppressor, homolog 1 (Drosophila)

(Aliases: si:dkey-181i3.5,zgc:123219,MGC123219,wu:fc19a11,Lats)

lats1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle tissue developmentGO:00605371100.353
nucleic acid metabolic processGO:00903042440.350
striated muscle tissue developmentGO:00147061100.280
cell migrationGO:00164772370.238
regulation of i kappab kinase nf kappab signalingGO:004312240.227
muscle cell developmentGO:00550011150.214
positive regulation of transportGO:005105020.200
neuroblast fate commitmentGO:001401710.193
cell motilityGO:00488702440.183
cellular component movementGO:00069283350.182
muscle fiber developmentGO:0048747520.180
signal transductionGO:00071654550.177
muscle organ developmentGO:00075171010.172
muscle structure developmentGO:00610611960.152
striated muscle cell differentiationGO:00511461290.149
muscle cell differentiationGO:00426921390.147
regulation of rna metabolic processGO:00512522240.143
modification dependent macromolecule catabolic processGO:004363230.143
cellular response to nutrient levelsGO:003166920.140
digestive tract morphogenesisGO:00485462310.130
axis specificationGO:0009798430.124
positive regulation of secretion by cellGO:190353210.108
cell migration involved in gastrulationGO:0042074790.107
aromatic compound biosynthetic processGO:00194382170.107
embryonic limb morphogenesisGO:003032620.105
regulation of gene expressionGO:00104682650.103
angiogenesisGO:00015251580.099
germ line stem cell divisionGO:004207810.096
heart developmentGO:00075073130.094
positive regulation of i kappab kinase nf kappab signalingGO:004312330.094
regulation of protein transportGO:005122330.089
larval developmentGO:000216420.086
striated muscle cell developmentGO:00550021080.086
regulation of cardiac muscle tissue developmentGO:005502410.084
nitrogen compound metabolic processGO:00068073190.084
cellular component assemblyGO:00226071700.082
cardiac muscle tissue developmentGO:0048738480.076
regulation of reactive oxygen species metabolic processGO:200037720.076
tube morphogenesisGO:00352393490.073
biosynthetic processGO:00090582940.071
neuroblast differentiationGO:001401610.071
negative regulation of cytokine productionGO:000181810.070
brain developmentGO:00074202930.067
nuclear migrationGO:000709730.066
cellular response to organic substanceGO:00713101050.066
cellular response to external stimulusGO:007149620.062
rna biosynthetic processGO:00327741810.062
dna biosynthetic processGO:007189730.062
segmentationGO:0035282970.061
smooth muscle contractionGO:000693920.061
actomyosin structure organizationGO:0031032530.060
negative regulation of cytokine mediated signaling pathwayGO:000196020.059
stem cell fate commitmentGO:004886510.059
regulation of tube sizeGO:003515020.056
localization of cellGO:00516742440.053
steroid hormone mediated signaling pathwayGO:004340190.052
epithelium migrationGO:0090132250.052
determination of heart left right asymmetryGO:00613711170.051
negative regulation of response to cytokine stimulusGO:006076120.050
cellular amine metabolic processGO:004410620.050
rrna catabolic processGO:001607510.050
regulation of locomotionGO:0040012550.049
regulation of establishment of protein localizationGO:007020140.049
kupffer s vesicle developmentGO:0070121500.049
response to woundingGO:00096111160.048
regulation of blood vessel sizeGO:005088020.047
fin morphogenesisGO:0033334530.047
macromolecule biosynthetic processGO:00090592270.047
negative regulation of signal transductionGO:0009968940.047
pigmentationGO:0043473850.046
regulation of nitrogen compound metabolic processGO:00511712510.046
cell part morphogenesisGO:00329902460.045
response to vitaminGO:003327330.044
morphogenesis of an epitheliumGO:00020093330.044
regulation of macromolecule biosynthetic processGO:00105562250.044
growthGO:00400071740.043
cell surface receptor signaling pathwayGO:00071663250.043
negative regulation of cellular processGO:00485232830.043
fin regenerationGO:0031101510.042
cellular nitrogen compound biosynthetic processGO:00442712180.041
nucleic acid templated transcriptionGO:00976591810.041
cellular macromolecule metabolic processGO:00442603910.040
negative regulation of biological processGO:00485193040.040
embryo development ending in birth or egg hatchingGO:00097922710.040
somitogenesisGO:0001756870.040
gene expressionGO:00104672520.039
organic acid metabolic processGO:0006082310.039
positive regulation of blood circulationGO:190352420.039
rna metabolic processGO:00160702190.039
nephron morphogenesisGO:007202820.039
vasculature developmentGO:00019442780.039
regulation of cellular amine metabolic processGO:003323800.038
response to bacteriumGO:0009617580.038
energy reserve metabolic processGO:000611220.038
stress fiber assemblyGO:004314950.037
diencephalon developmentGO:0021536580.037
regulation of muscle contractionGO:000693730.036
response to stressGO:00069502630.035
reactive oxygen species biosynthetic processGO:190340910.035
morphogenesis of a branching structureGO:0001763210.035
camera type eye developmentGO:00430102220.034
negative regulation of defense responseGO:003134820.034
regulation of myotube differentiationGO:001083020.034
regulation of blood pressureGO:000821710.033
negative regulation of secretion by cellGO:190353120.033
regulation of response to cytokine stimulusGO:006075930.032
anterior posterior axis specificationGO:0009948200.032
negative regulation of signalingGO:0023057960.031
cardiac muscle cell developmentGO:0055013200.031
cellular component biogenesisGO:00440851780.031
regulation of cell motilityGO:2000145460.031
developmental growthGO:00485891660.031
negative regulation of protein transportGO:005122430.030
cellular nitrogen compound metabolic processGO:00346412900.030
protein importGO:001703830.030
epithelial tube morphogenesisGO:00605621480.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
regulation of cellular amino acid metabolic processGO:000652100.030
nucleobase containing compound biosynthetic processGO:00346542050.029
regulation of cellular biosynthetic processGO:00313262450.029
protein polyubiquitinationGO:000020940.029
i kappab kinase nf kappab signalingGO:000724940.029
system processGO:00030081850.028
cellular macromolecule biosynthetic processGO:00346452240.028
regulation of organ morphogenesisGO:2000027350.028
positive regulation of striated muscle tissue developmentGO:004584410.027
mitotic g2 dna damage checkpointGO:000709530.027
fatty acid biosynthetic processGO:000663340.027
regulation of synaptic plasticityGO:004816710.027
regulation of cellular component movementGO:0051270550.027
negative regulation of mitosisGO:004583930.027
positive regulation of cytokine productionGO:000181920.027
reactive nitrogen species metabolic processGO:200105700.026
heart loopingGO:0001947940.026
nephron tubule morphogenesisGO:007207810.026
positive regulation of secretionGO:005104710.026
transcription from rna polymerase ii promoterGO:0006366800.026
meiotic nuclear divisionGO:000712640.026
epithelial cell migrationGO:0010631250.026
regulation of metal ion transportGO:001095940.026
macromolecular complex assemblyGO:0065003350.025
stem cell divisionGO:001714510.025
protein secretionGO:000930610.025
regulation of cell communicationGO:00106462320.025
cellular amino acid metabolic processGO:000652070.025
protein complex assemblyGO:0006461300.025
locomotionGO:00400113130.025
single organism organelle organizationGO:19025891990.025
regulation of cellular ketone metabolic processGO:001056570.024
interspecies interaction between organismsGO:004441940.024
microtubule cytoskeleton organization involved in mitosisGO:190285010.024
modification dependent protein catabolic processGO:001994130.024
rna splicingGO:0008380160.024
protein complex subunit organizationGO:0071822460.024
dorsal ventral pattern formationGO:00099531250.024
convergent extension involved in gastrulationGO:0060027710.023
digestive tract developmentGO:00485652650.023
nuclear importGO:005117030.023
endocardial cushion formationGO:000327220.023
ameboidal type cell migrationGO:00016671430.023
regulation of protein ubiquitinationGO:003139630.023
amine metabolic processGO:000930820.023
organic cyclic compound biosynthetic processGO:19013622230.023
regulation of muscle organ developmentGO:004863490.023
erk1 and erk2 cascadeGO:007037140.022
skeletal muscle organ developmentGO:0060538780.022
response to organic substanceGO:00100331530.022
embryonic heart tube morphogenesisGO:00031431080.022
g1 s transition of mitotic cell cycleGO:000008210.021
regulation of macromolecule metabolic processGO:00602553170.021
maintenance of locationGO:005123540.021
positive regulation of muscle organ developmentGO:004863610.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
biomineral tissue developmentGO:0031214130.021
negative regulation of response to stimulusGO:00485851040.021
g protein coupled receptor signaling pathwayGO:0007186740.021
appendage developmentGO:0048736800.021
camera type eye morphogenesisGO:00485931080.020
ncrna catabolic processGO:003466110.020
cellular response to oxygen levelsGO:007145310.020
embryonic organ morphogenesisGO:00485622740.020
skeletal muscle tissue developmentGO:0007519670.020
embryonic axis specificationGO:0000578120.020
negative regulation of cell communicationGO:0010648960.020
establishment of nucleus localizationGO:004002370.020
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
appendage morphogenesisGO:0035107560.019
hematopoietic stem cell differentiationGO:0060218200.019
protein homooligomerizationGO:005126030.019
cardiac cell developmentGO:0055006210.019
digestive system developmentGO:00551232890.019
renal tubule morphogenesisGO:006133310.019
primitive erythrocyte differentiationGO:006031950.019
oxoacid metabolic processGO:0043436310.019
protein acetylationGO:000647320.019
cellular extravasationGO:004512310.019
cell fate specificationGO:0001708680.018
cellular response to extracellular stimulusGO:003166820.018
eye developmentGO:00016542770.018
negative regulation of gene expressionGO:0010629650.018
positive regulation of response to stimulusGO:0048584800.018
regulation of glial cell differentiationGO:004568540.018
positive regulation of erk1 and erk2 cascadeGO:007037420.018
nucleobase containing compound metabolic processGO:00061392740.018
positive regulation of cell cycleGO:004578730.018
regulation of cytokine mediated signaling pathwayGO:000195930.018
cellular ketone metabolic processGO:0042180110.018
cellular response to fatty acidGO:007139830.018
endocrine processGO:005088620.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
cellular protein catabolic processGO:004425740.017
regulation of organ growthGO:004662030.017
cellular biosynthetic processGO:00442492860.017
chordate embryonic developmentGO:00430092710.017
ubiquitin dependent protein catabolic processGO:000651130.017
regulation of cell killingGO:003134120.017
blood vessel morphogenesisGO:00485142160.017
heterocycle metabolic processGO:00464832900.017
peptidyl serine phosphorylationGO:001810510.017
carboxylic acid metabolic processGO:0019752220.017
mitochondrion organizationGO:000700540.017
sensory organ developmentGO:00074233930.017
regulation of signal transductionGO:00099662250.017
cellular response to steroid hormone stimulusGO:0071383310.016
positive regulation of histone modificationGO:003105810.016
positive regulation of muscle tissue developmentGO:190186310.016
regulation of cellular metabolic processGO:00313233200.016
tissue migrationGO:0090130370.016
regulation of cell differentiationGO:00455951420.016
positive regulation of cell divisionGO:005178120.016
cellular component assembly involved in morphogenesisGO:00109271070.016
blood vessel endothelial cell migrationGO:0043534180.016
mitotic g2 m transition checkpointGO:004481830.016
cell projection organizationGO:00300302840.016
negative regulation of hormone secretionGO:004688820.016
regulation of rna biosynthetic processGO:20011412130.015
head developmentGO:00603223030.015
blood coagulationGO:0007596120.015
negative regulation of transcription dna templatedGO:0045892450.015
response to lipidGO:0033993600.015
positive regulation of cell proliferationGO:0008284150.015
negative regulation of secretionGO:005104820.015
multicellular organism growthGO:003526440.015
proteasomal protein catabolic processGO:001049820.015
positive regulation of locomotionGO:0040017140.015
axon guidanceGO:0007411860.015
regulation of protein localization to nucleusGO:190018020.015
protein complex biogenesisGO:0070271300.015
cellular response to decreased oxygen levelsGO:003629410.015
cell proliferationGO:0008283800.015
negative regulation of rna metabolic processGO:0051253480.014
regulation of mrna processingGO:005068430.014
positive regulation of chromosome organizationGO:200125210.014
negative regulation of protein phosphorylationGO:000193340.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
cellular response to lipidGO:0071396390.014
protein complex localizationGO:003150310.014
spliceosomal complex assemblyGO:000024510.014
meiosis iGO:000712710.014
phosphatidylinositol mediated signalingGO:004801520.014
cell migration to the midline involved in heart developmentGO:0003318120.014
blood vessel developmentGO:00015682460.014
zymogen activationGO:003163830.014
specification of symmetryGO:00097992040.014
cellular macromolecular complex assemblyGO:0034622240.014
positive regulation of rho protein signal transductionGO:003502500.014
female gonad developmentGO:000858540.014
response to nutrientGO:000758430.014
positive regulation of striated muscle cell differentiationGO:005115510.013
macromolecular complex disassemblyGO:003298410.013
regulation of synapse organizationGO:005080730.013
regulation of transcription dna templatedGO:00063552130.013
gastrulationGO:00073692080.013
astrocyte differentiationGO:004870810.013
mitotic dna integrity checkpointGO:004477440.013
limb morphogenesisGO:003510870.013
cellular aromatic compound metabolic processGO:00067252950.013
regulation of response to oxidative stressGO:190288220.013
macromolecular complex subunit organizationGO:0043933740.013
nephron epithelium morphogenesisGO:007208810.013
regulation of primary metabolic processGO:00800903110.013
regulation of calcium ion transportGO:005192420.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
stem cell maintenanceGO:001982740.012
positive regulation of muscle cell differentiationGO:005114910.012
bone mineralizationGO:003028290.012
ear developmentGO:00435831270.012
negative regulation of bmp signaling pathwayGO:0030514130.012
regulation of multicellular organismal developmentGO:20000262230.012
embryonic heart tube developmentGO:00350501330.012
water homeostasisGO:003010440.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of epithelial cell proliferationGO:005067830.012
hindbrain morphogenesisGO:0021575220.012
organic substance biosynthetic processGO:19015762890.012
regulation of cytokine productionGO:000181730.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
neuron developmentGO:00486662620.011
organelle organizationGO:00069962270.011
transcription dna templatedGO:00063511810.011
regulation of cytoplasmic transportGO:190364940.011
reproductionGO:0000003400.011
positive regulation of ras protein signal transductionGO:004657910.011
fertilizationGO:000956630.011
spindle assemblyGO:005122520.011
central nervous system developmentGO:00074173870.011
myotube cell developmentGO:0014904350.011
response to glucocorticoidGO:005138410.011
mitotic cell cycle embryonicGO:004544820.011
anterior posterior pattern specificationGO:00099521520.011
positive regulation of wound healingGO:009030310.011
blood circulationGO:0008015870.011
leukocyte mediated cytotoxicityGO:000190910.011
cardiocyte differentiationGO:0035051440.011
interaction with hostGO:005170140.011
negative regulation of i kappab kinase nf kappab signalingGO:004312410.011
behaviorGO:0007610740.011
cranial nerve developmentGO:0021545420.011
cellular response to starvationGO:000926710.011
cellular component disassemblyGO:002241110.011
cell cycleGO:0007049930.011
embryonic hemopoiesisGO:0035162530.011
cellular modified amino acid metabolic processGO:000657530.010
killing of cells in other organism involved in symbiotic interactionGO:005188310.010
hatching gland developmentGO:004878530.010
regulation of meiotic cell cycleGO:005144510.010
embryonic skeletal joint morphogenesisGO:006027230.010

lats1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
immune system diseaseDOID:291400.019