Danio rerio

33 known processes

nrg2a

neuregulin 2a

(Aliases: zgc:162973)

nrg2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleic acid templated transcriptionGO:00976591810.936
regulation of rna biosynthetic processGO:20011412130.907
nucleobase containing compound metabolic processGO:00061392740.891
regulation of biosynthetic processGO:00098892500.878
regulation of nucleobase containing compound metabolic processGO:00192192500.863
regulation of macromolecule biosynthetic processGO:00105562250.809
regulation of cellular metabolic processGO:00313233200.802
regulation of cellular macromolecule biosynthetic processGO:20001122220.790
regulation of metabolic processGO:00192223590.773
positive regulation of cellular processGO:00485222010.773
heterocycle biosynthetic processGO:00181302150.771
cellular nitrogen compound metabolic processGO:00346412900.770
nucleic acid metabolic processGO:00903042440.768
central nervous system developmentGO:00074173870.762
cell migrationGO:00164772370.735
regulation of macromolecule metabolic processGO:00602553170.732
regionalizationGO:00030022740.727
cell morphogenesisGO:00009022890.708
negative regulation of biological processGO:00485193040.695
cellular macromolecule metabolic processGO:00442603910.686
positive regulation of cellular component biogenesisGO:004408930.682
cell morphogenesis involved in differentiationGO:00009041950.671
cellular aromatic compound metabolic processGO:00067252950.660
ameboidal type cell migrationGO:00016671430.645
signal transductionGO:00071654550.629
apoptotic processGO:00069151160.611
cellular biosynthetic processGO:00442492860.610
nucleobase containing compound biosynthetic processGO:00346542050.610
rna biosynthetic processGO:00327741810.608
organic cyclic compound metabolic processGO:19013603010.603
regulation of signalingGO:00230512350.590
blood vessel developmentGO:00015682460.585
cellular macromolecule biosynthetic processGO:00346452240.583
digestive system developmentGO:00551232890.581
nitrogen compound metabolic processGO:00068073190.577
organic cyclic compound biosynthetic processGO:19013622230.561
transcription dna templatedGO:00063511810.549
regulation of nitrogen compound metabolic processGO:00511712510.542
negative regulation of cellular processGO:00485232830.540
regulation of transcription from rna polymerase ii promoterGO:00063571140.537
localization of cellGO:00516742440.534
cellular nitrogen compound biosynthetic processGO:00442712180.525
positive regulation of rna biosynthetic processGO:1902680570.522
regulation of transcription dna templatedGO:00063552130.515
positive regulation of biological processGO:00485182530.498
digestive tract developmentGO:00485652650.494
neuron projection morphogenesisGO:00488121610.493
regulation of rna metabolic processGO:00512522240.485
cell deathGO:00082191210.481
regulation of multicellular organismal processGO:00512392770.478
positive regulation of metabolic processGO:00098931080.476
regulation of primary metabolic processGO:00800903110.467
regulation of nucleic acid templated transcriptionGO:19035062130.462
cell projection organizationGO:00300302840.459
cellular component movementGO:00069283350.455
positive regulation of multicellular organismal processGO:0051240520.454
regulation of extrinsic apoptotic signaling pathwayGO:200123630.454
vasculature developmentGO:00019442780.452
cell migration involved in gastrulationGO:0042074790.451
negative regulation of apoptotic processGO:0043066550.448
regulation of developmental processGO:00507932470.445
cellular component morphogenesisGO:00329893360.440
negative regulation of cellular metabolic processGO:0031324770.439
otic vesicle formationGO:0030916270.436
growthGO:00400071740.433
aromatic compound biosynthetic processGO:00194382170.427
cell part morphogenesisGO:00329902460.416
negative regulation of multicellular organismal processGO:0051241690.415
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.413
phosphate containing compound metabolic processGO:00067961080.409
regulation of apoptotic processGO:0042981980.404
dorsal convergenceGO:0060030140.403
axon developmentGO:00615641660.390
biosynthetic processGO:00090582940.381
heterocycle metabolic processGO:00464832900.380
positive regulation of cell cycleGO:004578730.377
positive regulation of nucleobase containing compound metabolic processGO:0045935690.372
larval developmentGO:000216420.370
rna metabolic processGO:00160702190.370
regulation of signal transductionGO:00099662250.368
cell projection morphogenesisGO:00488582440.362
locomotionGO:00400113130.360
positive regulation of macromolecule metabolic processGO:0010604930.358
regulation of cellular biosynthetic processGO:00313262450.356
extrinsic apoptotic signaling pathwayGO:009719130.353
regulation of gene expressionGO:00104682650.352
chordate embryonic developmentGO:00430092710.352
regulation of biological qualityGO:00650082630.348
cellular response to external stimulusGO:007149620.345
negative regulation of cell deathGO:0060548600.341
tube morphogenesisGO:00352393490.339
regulation of cell communicationGO:00106462320.336
developmental growthGO:00485891660.334
response to chemicalGO:00422213200.330
regulation of response to stimulusGO:00485832690.326
digestive tract morphogenesisGO:00485462310.326
positive regulation of gene expressionGO:0010628710.326
protein modification processGO:00362111000.319
protein localization to nucleusGO:003450430.316
generation of neuronsGO:00486993850.310
transcription from rna polymerase ii promoterGO:0006366800.305
regulation of synapse organizationGO:005080730.302
specification of symmetryGO:00097992040.295
regulation of response to oxidative stressGO:190288220.295
positive regulation of catabolic processGO:000989640.291
regulation of cell deathGO:00109411030.291
heart developmentGO:00075073130.287
bmp signaling pathwayGO:0030509520.286
regulation of oocyte developmentGO:006028130.284
macromolecule biosynthetic processGO:00090592270.283
positive regulation of biosynthetic processGO:0009891680.283
programmed cell deathGO:00125011190.277
neuron projection developmentGO:00311751800.275
regulation of multicellular organismal developmentGO:20000262230.269
neuron developmentGO:00486662620.268
muscle structure developmentGO:00610611960.266
eye developmentGO:00016542770.263
negative regulation of developmental processGO:0051093650.263
deathGO:00162651210.262
neuron differentiationGO:00301823530.258
positive regulation of cell differentiationGO:0045597300.256
negative regulation of protein serine threonine kinase activityGO:007190120.252
muscle cell differentiationGO:00426921390.252
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.251
organic substance biosynthetic processGO:19015762890.250
protein metabolic processGO:00195381830.250
positive regulation of nitrogen compound metabolic processGO:0051173690.249
cell surface receptor signaling pathwayGO:00071663250.246
phosphorus metabolic processGO:00067931090.246
cell growthGO:0016049570.245
regulation of protein bindingGO:004339330.245
positive regulation of cellular metabolic processGO:0031325940.242
multicellular organism growthGO:003526440.239
otic placode formationGO:0043049230.234
regulation of cell differentiationGO:00455951420.233
cell morphogenesis involved in neuron differentiationGO:00486671630.231
regulation of cellular carbohydrate metabolic processGO:001067540.230
phosphorylationGO:0016310690.228
regulation of phosphorus metabolic processGO:0051174430.225
regulation of programmed cell deathGO:00430671010.225
positive regulation of nucleic acid templated transcriptionGO:1903508570.218
anterior posterior pattern specificationGO:00099521520.217
small molecule metabolic processGO:0044281770.215
response to abiotic stimulusGO:00096281220.215
regulation of embryonic developmentGO:0045995470.212
cellular response to chemical stimulusGO:00708871570.212
axonogenesisGO:00074091520.211
cellular response to nutrient levelsGO:003166920.211
regulation of anatomical structure morphogenesisGO:00226031300.210
cellular carbohydrate metabolic processGO:004426240.210
brain developmentGO:00074202930.207
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.207
mesodermal cell migrationGO:0008078120.205
female gonad developmentGO:000858540.199
cellular protein modification processGO:00064641000.199
embryo development ending in birth or egg hatchingGO:00097922710.195
nuclear transportGO:005116940.193
apoptotic signaling pathwayGO:0097190230.192
morphogenesis of an epitheliumGO:00020093330.189
taxisGO:00423301090.183
regulation of protein transportGO:005122330.182
negative regulation of programmed cell deathGO:0043069580.182
neuron projection extensionGO:1990138450.182
positive regulation of rna metabolic processGO:0051254590.182
regulation of cytoplasmic transportGO:190364940.181
determination of bilateral symmetryGO:00098552040.181
single organism metabolic processGO:00447102170.181
negative regulation of protein phosphorylationGO:000193340.176
forebrain developmentGO:0030900960.172
sensory organ developmentGO:00074233930.170
regulation of cellular component movementGO:0051270550.170
central nervous system neuron axonogenesisGO:0021955180.166
regulation of cell morphogenesisGO:0022604420.166
otic vesicle morphogenesisGO:0071600340.165
cell cell signalingGO:0007267520.164
response to steroid hormoneGO:0048545350.163
organonitrogen compound metabolic processGO:1901564740.162
regulation of establishment of protein localizationGO:007020140.160
regulation of cellular component organizationGO:0051128860.158
developmental process involved in reproductionGO:0003006270.157
positive regulation of cellular biosynthetic processGO:0031328680.156
biological adhesionGO:0022610400.155
regulation of protein localization to nucleusGO:190018020.154
response to estradiolGO:003235560.154
regulation of bindingGO:005109830.153
negative regulation of cellular biosynthetic processGO:0031327550.152
tissue regenerationGO:0042246740.152
small gtpase mediated signal transductionGO:000726480.151
sensory organ morphogenesisGO:00905962000.151
macromolecule modificationGO:00434121110.150
negative regulation of signalingGO:0023057960.149
regulation of anatomical structure sizeGO:0090066330.149
negative regulation of mapk cascadeGO:004340940.148
determination of heart left right asymmetryGO:00613711170.148
hindbrain developmentGO:0030902910.146
chemotaxisGO:00069351040.146
single organism localizationGO:19025782250.145
oocyte maturationGO:000155640.143
negative regulation of signal transductionGO:0009968940.142
positive regulation of transportGO:005105020.140
blood vessel morphogenesisGO:00485142160.140
negative regulation of response to stimulusGO:00485851040.139
system processGO:00030081850.138
positive regulation of signalingGO:0023056560.137
cellular component biogenesisGO:00440851780.137
gene expressionGO:00104672520.137
developmental cell growthGO:0048588520.136
dorsal ventral pattern formationGO:00099531250.136
response to organic substanceGO:00100331530.135
intracellular signal transductionGO:0035556850.134
positive regulation of developmental processGO:0051094500.134
negative regulation of macromolecule metabolic processGO:0010605760.134
negative regulation of cell differentiationGO:0045596460.133
response to external stimulusGO:00096052640.132
response to stressGO:00069502630.131
nucleocytoplasmic transportGO:000691340.129
erk1 and erk2 cascadeGO:007037140.128
regulation of cell growthGO:0001558290.127
stem cell maintenanceGO:001982740.126
mesenchymal cell differentiationGO:0048762870.125
gastrulationGO:00073692080.123
cell adhesionGO:0007155400.123
endocrine system developmentGO:0035270650.122
enzyme linked receptor protein signaling pathwayGO:00071671060.122
mesenchyme developmentGO:00604851270.122
cell motilityGO:00488702440.120
embryonic organ developmentGO:00485683810.120
kidney developmentGO:0001822920.119
regulation of cell migrationGO:0030334400.119
regulation of organ growthGO:004662030.119
determination of left right symmetryGO:00073681790.117
hematopoietic or lymphoid organ developmentGO:00485341910.117
stem cell differentiationGO:00488631170.116
head developmentGO:00603223030.116
regulation of cell adhesionGO:0030155150.115
regulation of cell morphogenesis involved in differentiationGO:0010769380.114
astrocyte differentiationGO:004870810.114
negative regulation of metabolic processGO:0009892860.113
stem cell developmentGO:0048864820.113
fin regenerationGO:0031101510.109
regulation of molecular functionGO:0065009700.109
cognitionGO:005089010.109
cellular amine metabolic processGO:004410620.108
cellular ketone metabolic processGO:0042180110.108
regulation of growthGO:0040008420.107
agingGO:000756820.105
positive regulation of transcription dna templatedGO:0045893570.105
ear developmentGO:00435831270.105
regulation of protein catabolic processGO:004217610.105
development of primary female sexual characteristicsGO:004654540.103
cellular localizationGO:0051641970.103
mesenchymal cell developmentGO:0014031780.102
regulation of neuron differentiationGO:0045664560.101
negative regulation of protein kinase activityGO:000646940.099
somite developmentGO:0061053960.099
central nervous system neuron developmentGO:0021954290.098
response to endogenous stimulusGO:0009719830.098
regulation of synapse assemblyGO:005196330.098
positive regulation of cellular catabolic processGO:003133130.096
regulation of cellular ketone metabolic processGO:001056570.096
regulation of sequestering of calcium ionGO:005128240.096
synaptic growth at neuromuscular junctionGO:005112420.096
circadian sleep wake cycleGO:004274520.096
positive regulation of macromolecule biosynthetic processGO:0010557590.094
heart joggingGO:0003146400.094
peptidyl serine phosphorylationGO:001810510.093
regulation of developmental growthGO:0048638380.093
axon extensionGO:0048675450.092
striated muscle tissue developmentGO:00147061100.091
cellular response to organic substanceGO:00713101050.090
positive regulation of axon extensionGO:004577350.089
positive regulation of nervous system developmentGO:0051962250.088
oxoacid metabolic processGO:0043436310.088
protein importGO:001703830.087
regulation of stem cell differentiationGO:200073640.087
gland developmentGO:00487321430.087
regulation of localizationGO:00328791040.086
positive regulation of dna metabolic processGO:005105410.086
cellular response to starvationGO:000926710.086
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.085
response to hexoseGO:000974630.085
circulatory system processGO:0003013870.085
regulation of locomotionGO:0040012550.084
multicellular organismal reproductive processGO:0048609350.084
negative regulation of macromolecule biosynthetic processGO:0010558480.083
cellular amino acid metabolic processGO:000652070.083
negative regulation of signal transduction in absence of ligandGO:190109910.081
blood circulationGO:0008015870.081
ectodermal placode formationGO:0060788260.081
cellular response to extracellular stimulusGO:003166820.081
g protein coupled receptor signaling pathwayGO:0007186740.080
stem cell divisionGO:001714510.080
cell fate commitmentGO:0045165990.079
release of sequestered calcium ion into cytosolGO:005120930.079
regulation of intracellular signal transductionGO:1902531570.078
urogenital system developmentGO:0001655970.078
negative regulation of nucleobase containing compound metabolic processGO:0045934590.077
protein phosphorylationGO:0006468470.077
positive regulation of cellular amino acid metabolic processGO:004576400.077
nuclear importGO:005117030.077
regulation of cell motilityGO:2000145460.077
regulation of skeletal muscle tissue developmentGO:004864140.077
negative regulation of kinase activityGO:003367340.076
regulation of protein metabolic processGO:0051246560.076
cellular component assemblyGO:00226071700.075
regulation of cellular amine metabolic processGO:003323800.075
negative regulation of biosynthetic processGO:0009890550.075
protein import into nucleusGO:000660630.074
organic substance catabolic processGO:1901575280.073
signal transduction in absence of ligandGO:003803410.073
nephron epithelium morphogenesisGO:007208810.073
inner ear developmentGO:00488391260.073
regulation of dna replicationGO:000627530.073
cellular response to hypoxiaGO:007145610.072
regulation of cellular protein metabolic processGO:0032268520.072
positive regulation of map kinase activityGO:004340630.072
regenerationGO:0031099910.072
otic vesicle developmentGO:0071599420.071
negative regulation of gene expressionGO:0010629650.071
regulation of reproductive processGO:200024140.070
hepaticobiliary system developmentGO:0061008980.070
regulation of skeletal muscle fiber developmentGO:004874220.070
positive regulation of cellular carbohydrate metabolic processGO:001067610.069
organic substance transportGO:0071702580.069
circadian sleep wake cycle processGO:002241020.068
wound healingGO:0042060900.068
cartilage developmentGO:0051216960.068
cellular protein metabolic processGO:00442671290.068
homeostatic processGO:00425921420.067
regulation of phosphate metabolic processGO:0019220430.067
gamete generationGO:0007276330.066
endodermal cell fate determinationGO:000749320.065
negative regulation of phosphate metabolic processGO:0045936130.064
multicellular organism reproductionGO:0032504350.063
maintenance of locationGO:005123540.063
regulation of cell developmentGO:00602841000.063
cell cycleGO:0007049930.063
germ line stem cell maintenanceGO:003071820.062
regulation of wound healingGO:006104120.062
regulation of immune system processGO:0002682340.061
response to estrogenGO:0043627270.061
regulation of multicellular organism growthGO:004001440.061
forebrain cell migrationGO:002188510.061
cellular response to stressGO:0033554620.061
segmentationGO:0035282970.061
cell cell signaling involved in cell fate commitmentGO:0045168120.060
protein complex biogenesisGO:0070271300.059
oocyte differentiationGO:0009994140.059
regulation of nervous system developmentGO:0051960900.059
regulation of protein targetingGO:190353320.059
establishment of localization in cellGO:0051649770.058
single organism biosynthetic processGO:0044711710.058
hemopoiesisGO:00300971830.058
negative regulation of cell cycleGO:0045786140.058
macromolecular complex subunit organizationGO:0043933740.058
regulation of nucleocytoplasmic transportGO:004682220.058
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.057
response to hormoneGO:0009725480.057
reactive oxygen species biosynthetic processGO:190340910.057
regulation of cell sizeGO:0008361290.056
carbohydrate metabolic processGO:0005975120.056
response to drugGO:004249330.056
positive regulation of secretionGO:005104710.056
protein polymerizationGO:005125840.055
multi organism processGO:00517041340.055
amine metabolic processGO:000930820.055
immune system processGO:00023762410.055
response to woundingGO:00096111160.055
nephron tubule morphogenesisGO:007207810.055
adult behaviorGO:003053420.054
single organism nuclear importGO:190259330.054
post embryonic organ developmentGO:004856940.054
macromolecule localizationGO:0033036540.053
negative regulation of cell fate specificationGO:0009996110.053
regulation of catalytic activityGO:0050790550.053
regulation of cellular amino acid metabolic processGO:000652100.053
regulation of response to external stimulusGO:0032101310.053
renal system developmentGO:0072001940.052
ras protein signal transductionGO:000726570.052
central nervous system projection neuron axonogenesisGO:0021952150.052
liver developmentGO:0001889960.052
heart contractionGO:0060047710.052
embryonic heart tube developmentGO:00350501330.051
negative regulation of molecular functionGO:0044092230.051
sexual reproductionGO:0019953360.051
cell substrate adhesionGO:003158940.051
regulation of response to cytokine stimulusGO:006075930.050
peptidyl serine modificationGO:001820920.050
regulation of blood pressureGO:000821710.050
negative regulation of cell communicationGO:0010648960.050
cellular response to decreased oxygen levelsGO:003629410.049
response to oxygen containing compoundGO:1901700550.049
positive regulation of cellular component organizationGO:0051130130.049
regulation of cell cycleGO:0051726520.049
regulation of neurogenesisGO:0050767870.048
organic acid metabolic processGO:0006082310.048
signal transduction by phosphorylationGO:0023014180.047
establishment of protein localization to organelleGO:007259440.047
regulation of response to stressGO:0080134360.047
regulation of heart morphogenesisGO:2000826170.047
positive regulation of protein polymerizationGO:003227320.047
regulation of protein phosphorylationGO:0001932180.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.046
determination of dorsal ventral asymmetryGO:0048262340.046
glial cell migrationGO:000834730.045
cellular response to endogenous stimulusGO:0071495680.045
stem cell proliferationGO:007208940.045
cellular response to hormone stimulusGO:0032870390.045
heart loopingGO:0001947940.045
synapse assemblyGO:000741690.045
germ cell developmentGO:0007281220.045
nephron morphogenesisGO:007202820.044
morphogenesis of a branching epitheliumGO:0061138160.044
regulation of cell projection organizationGO:0031344440.043
response to nutrientGO:000758430.043
angiogenesisGO:00015251580.043
cellular macromolecular complex assemblyGO:0034622240.043
regulation of peptidase activityGO:0052547230.043
negative regulation of neurogenesisGO:0050768200.043
protein targeting to nucleusGO:004474430.043
negative regulation of nitrogen compound metabolic processGO:0051172590.043
regulation of mitotic cell cycleGO:0007346250.043
negative regulation of sequestering of calcium ionGO:005128340.043
regulation of axon regenerationGO:004867970.043
synaptic transmissionGO:0007268350.043
axon guidanceGO:0007411860.043
renal tubule morphogenesisGO:006133310.043
regulation of bmp signaling pathwayGO:0030510390.043
response to lipidGO:0033993600.042
organelle organizationGO:00069962270.042
developmental growth involved in morphogenesisGO:0060560860.042
cell divisionGO:0051301200.042
cell proliferationGO:0008283800.042
negative regulation of rna metabolic processGO:0051253480.042
single organism reproductive processGO:0044702400.041
regulation of autophagyGO:001050630.041
autophagyGO:000691440.041
cellular process involved in reproduction in multicellular organismGO:0022412280.041
response to monosaccharideGO:003428430.041
immune system developmentGO:00025201910.041
ectodermal placode morphogenesisGO:0071697320.041
regulation of circadian sleep wake cycle sleepGO:004518710.040
adherens junction organizationGO:003433240.040
neural crest cell differentiationGO:0014033720.040
calcium ion transport into cytosolGO:006040230.040
positive regulation of carbohydrate metabolic processGO:004591310.040
epithelial cell migrationGO:0010631250.040
covalent chromatin modificationGO:0016569200.039
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.039
actin filament based processGO:0030029640.039
regulation of phosphorylationGO:0042325260.039
chemical homeostasisGO:0048878490.039
sleepGO:003043110.039
negative regulation of catalytic activityGO:0043086210.039
positive regulation of response to stimulusGO:0048584800.038
positive regulation of muscle organ developmentGO:004863610.038
positive regulation of cytosolic calcium ion concentrationGO:000720440.038
convergent extensionGO:00600261180.038
negative regulation of catabolic processGO:000989530.038
response to oxygen levelsGO:0070482250.037
cellular response to lipidGO:0071396390.037
regulation of striated muscle tissue developmentGO:001620260.037
regulation of nucleoside metabolic processGO:000911820.037
female gamete generationGO:0007292140.037
response to reactive oxygen speciesGO:000030250.037
regulation of hydrolase activityGO:0051336280.037
embryonic organ morphogenesisGO:00485622740.037
oocyte developmentGO:0048599140.036
regulation of canonical wnt signaling pathwayGO:0060828340.036
neuron projection guidanceGO:0097485860.036
camera type eye developmentGO:00430102220.036
oogenesisGO:0048477140.036
somitogenesisGO:0001756870.036
intracellular transportGO:0046907320.036
regulation of intracellular protein transportGO:003315730.036
sequestering of calcium ionGO:005120830.036
positive regulation of cell developmentGO:0010720250.036
mapk cascadeGO:0000165180.036
regulation of protein import into nucleusGO:004230620.036
ossificationGO:0001503230.035
negative regulation of map kinase activityGO:004340720.035
regulation of transportGO:0051049450.035
diencephalon developmentGO:0021536580.035
macromolecule catabolic processGO:0009057150.035
macroautophagyGO:001623610.035
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.035
sequestering of metal ionGO:005123830.035
heart morphogenesisGO:00030071560.035
positive regulation of cell adhesionGO:004578510.035
regulation of tube sizeGO:003515020.034
positive regulation of cell communicationGO:0010647560.034

nrg2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.104
bone diseaseDOID:008000100.104
bone development diseaseDOID:008000600.104
disease of anatomical entityDOID:700.104
musculoskeletal system diseaseDOID:1700.104