Danio rerio

0 known processes

usp4

ubiquitin specific protease 4 (proto-oncogene)

(Aliases: im:7139722,unpEL,wu:fa11d11)

usp4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to stressGO:00069502630.282
cellular macromolecule metabolic processGO:00442603910.259
Human
signal transductionGO:00071654550.231
mitochondrion organizationGO:000700540.205
larval developmentGO:000216420.171
protein importGO:001703830.167
regulation of cellular metabolic processGO:00313233200.165
Human
cellular protein catabolic processGO:004425740.155
modification dependent macromolecule catabolic processGO:004363230.151
establishment of protein localization to organelleGO:007259440.147
regulation of protein catabolic processGO:004217610.147
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.145
nuclear transportGO:005116940.138
agingGO:000756820.132
regulation of macromolecule metabolic processGO:00602553170.128
Human
cellular protein metabolic processGO:00442671290.125
Human
gene expressionGO:00104672520.124
Human
proteolysis involved in cellular protein catabolic processGO:005160330.123
regulation of protein transportGO:005122330.122
negative regulation of protein phosphorylationGO:000193340.119
regulation of signal transductionGO:00099662250.118
mitotic dna integrity checkpointGO:004477440.118
regulation of establishment of protein localizationGO:007020140.116
regulation of metabolic processGO:00192223590.115
Human
protein metabolic processGO:00195381830.107
Human
g2 dna damage checkpointGO:003157230.102
mitochondrial transportGO:000683920.101
macromolecule modificationGO:00434121110.100
Human
mitotic g2 m transition checkpointGO:004481830.099
cell surface receptor signaling pathwayGO:00071663250.098
protein modification processGO:00362111000.098
Human
organelle organizationGO:00069962270.094
regulation of protein modification by small protein conjugation or removalGO:190332030.093
Human
regulation of gene expressionGO:00104682650.090
Human
cellular component movementGO:00069283350.088
protein targeting to nucleusGO:004474430.087
modification dependent protein catabolic processGO:001994130.087
positive regulation of biological processGO:00485182530.086
positive regulation of cellular component biogenesisGO:004408930.077
mitotic dna damage checkpointGO:004477340.076
maintenance of locationGO:005123540.075
mitotic g2 dna damage checkpointGO:000709530.074
regulation of protein metabolic processGO:0051246560.073
Human
single organism nuclear importGO:190259330.073
establishment of localizationGO:00512342440.073
negative regulation of mapk cascadeGO:004340940.071
protein complex subunit organizationGO:0071822460.071
negative regulation of protein kinase activityGO:000646940.067
regulation of cell communicationGO:00106462320.066
positive regulation of catabolic processGO:000989640.066
regulation of extrinsic apoptotic signaling pathwayGO:200123630.063
response to chemicalGO:00422213200.062
negative regulation of cytoplasmic transportGO:190365020.061
single organism organelle organizationGO:19025891990.059
ubiquitin dependent protein catabolic processGO:000651130.059
embryo development ending in birth or egg hatchingGO:00097922710.058
regulation of primary metabolic processGO:00800903110.057
Human
regulation of intracellular protein transportGO:003315730.056
locomotionGO:00400113130.055
tube morphogenesisGO:00352393490.055
cellular protein modification processGO:00064641000.055
Human
cell migrationGO:00164772370.054
digestive system developmentGO:00551232890.053
regulation of signalingGO:00230512350.053
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.053
regulation of response to stimulusGO:00485832690.053
digestive tract developmentGO:00485652650.052
negative regulation of cellular processGO:00485232830.051
Human
response to abiotic stimulusGO:00096281220.051
negative regulation of kinase activityGO:003367340.051
nucleocytoplasmic transportGO:000691340.049
negative regulation of biological processGO:00485193040.048
Human
cell motilityGO:00488702440.047
regulation of cytoplasmic transportGO:190364940.047
neuron differentiationGO:00301823530.047
regulation of protein complex assemblyGO:004325430.047
ribonucleoside monophosphate catabolic processGO:000915840.046
protein stabilizationGO:005082120.045
response to other organismGO:0051707970.045
meiotic nuclear divisionGO:000712640.045
negative regulation of map kinase activityGO:004340720.045
extrinsic apoptotic signaling pathwayGO:009719130.045
positive regulation of transportGO:005105020.045
regulation of cell shapeGO:000836010.044
negative regulation of protein transportGO:005122430.043
response to uvGO:000941130.043
single organism metabolic processGO:00447102170.043
localization of cellGO:00516742440.042
cellular component assemblyGO:00226071700.041
Human
proteasomal protein catabolic processGO:001049820.041
nuclear importGO:005117030.041
regulation of biological qualityGO:00650082630.040
Human
positive regulation of cellular catabolic processGO:003133130.040
cellular component biogenesisGO:00440851780.040
Human
intracellular signal transductionGO:0035556850.038
negative regulation of response to stimulusGO:00485851040.038
cell projection organizationGO:00300302840.038
macromolecule biosynthetic processGO:00090592270.038
phagocytosisGO:000690930.037
regulation of cellular protein metabolic processGO:0032268520.037
Human
protein localization to nucleusGO:003450430.036
phosphate containing compound metabolic processGO:00067961080.036
regulation of protein localization to nucleusGO:190018020.035
single fertilizationGO:000733830.035
regulation of mitotic cell cycleGO:0007346250.035
single organism transportGO:00447652060.035
protein import into nucleusGO:000660630.035
digestive tract morphogenesisGO:00485462310.035
synaptic vesicle transportGO:004848910.035
response to external stimulusGO:00096052640.034
negative regulation of signalingGO:0023057960.034
brain developmentGO:00074202930.034
cellular response to dna damage stimulusGO:0006974240.033
negative regulation of signal transductionGO:0009968940.033
regulation of cellular protein catabolic processGO:190336210.032
meiotic cell cycle processGO:190304630.032
single organism intracellular transportGO:1902582250.032
multicellular organism growthGO:003526440.032
cell morphogenesisGO:00009022890.032
response to biotic stimulusGO:0009607970.032
phosphorus metabolic processGO:00067931090.031
cell deathGO:00082191210.030
regulation of bindingGO:005109830.030
positive regulation of cell cycleGO:004578730.030
regulation of protein targetingGO:190353320.030
regulation of nucleocytoplasmic transportGO:004682220.029
positive regulation of response to stimulusGO:0048584800.029
cellular localizationGO:0051641970.029
Human
phosphorylationGO:0016310690.028
cell projection morphogenesisGO:00488582440.028
regulation of jun kinase activityGO:004350630.028
cytoskeleton organizationGO:0007010960.028
transcription from rna polymerase ii promoterGO:0006366800.028
regulation of developmental processGO:00507932470.028
negative regulation of catabolic processGO:000989530.028
positive regulation of signalingGO:0023056560.028
positive regulation of cellular processGO:00485222010.027
regulation of biosynthetic processGO:00098892500.027
gtp metabolic processGO:004603940.027
negative regulation of protein serine threonine kinase activityGO:007190120.027
positive regulation of cell activationGO:005086710.026
biosynthetic processGO:00090582940.026
negative regulation of mitosisGO:004583930.026
regulation of nucleoside metabolic processGO:000911820.026
deathGO:00162651210.026
protein complex assemblyGO:0006461300.026
gastrulationGO:00073692080.026
cell substrate adhesionGO:003158940.026
organic substance biosynthetic processGO:19015762890.025
response to topologically incorrect proteinGO:003596620.025
meiotic chromosome segregationGO:004513230.025
cellular component disassemblyGO:002241110.025
morphogenesis of an epitheliumGO:00020093330.025
cell cycle processGO:0022402530.025
intracellular transportGO:0046907320.025
regulation of protein import into nucleusGO:004230620.025
regulation of localizationGO:00328791040.025
neuron developmentGO:00486662620.025
negative regulation of intracellular transportGO:003238730.025
nitrogen compound metabolic processGO:00068073190.024
Human
immune system processGO:00023762410.024
generation of neuronsGO:00486993850.024
regulation of chromosome segregationGO:005198310.024
negative regulation of cell communicationGO:0010648960.024
cellular carbohydrate metabolic processGO:004426240.024
regulation of rna biosynthetic processGO:20011412130.024
programmed cell deathGO:00125011190.024
cellular biosynthetic processGO:00442492860.024
positive regulation of canonical wnt signaling pathwayGO:009026340.024
regulation of protein ubiquitinationGO:003139630.024
Human
regulation of cytokine productionGO:000181730.023
cellular macromolecule biosynthetic processGO:00346452240.023
cell part morphogenesisGO:00329902460.023
organonitrogen compound metabolic processGO:1901564740.023
negative regulation of cell cycle phase transitionGO:190198850.023
synaptic growth at neuromuscular junctionGO:005112420.023
fertilizationGO:000956630.023
mononuclear cell proliferationGO:003294310.023
protein complex biogenesisGO:0070271300.023
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.023
macromolecular complex subunit organizationGO:0043933740.022
Human
response to osmotic stressGO:0006970110.022
response to external biotic stimulusGO:0043207970.022
cellular amine metabolic processGO:004410620.022
regulation of intracellular signal transductionGO:1902531570.022
protein phosphorylationGO:0006468470.022
organic substance transportGO:0071702580.022
protein modification by small protein conjugation or removalGO:0070647140.022
Human
regulation of molecular functionGO:0065009700.022
spermatid differentiationGO:004851520.022
transportGO:00068102200.021
regionalizationGO:00030022740.021
apoptotic processGO:00069151160.021
intracellular receptor signaling pathwayGO:0030522300.021
somatic muscle developmentGO:000752540.021
negative regulation of apoptotic processGO:0043066550.021
double strand break repairGO:000630230.021
positive regulation of cell communicationGO:0010647560.021
pronuclear migrationGO:003504610.021
hemopoiesisGO:00300971830.021
negative regulation of macromolecule metabolic processGO:0010605760.021
Human
i kappab kinase nf kappab signalingGO:000724940.021
mitotic cell cycleGO:0000278640.020
lipid storageGO:001991510.020
regulation of meiotic cell cycleGO:005144510.020
regulation of nucleotide catabolic processGO:003081120.020
negative regulation of metabolic processGO:0009892860.020
Human
regulation of metal ion transportGO:001095940.020
central nervous system developmentGO:00074173870.020
nucleobase containing compound metabolic processGO:00061392740.020
Human
organic cyclic compound metabolic processGO:19013603010.020
Human
regulation of circadian rhythmGO:004275240.020
amine metabolic processGO:000930820.020
protein secretionGO:000930610.020
leukocyte proliferationGO:007066110.020
regulation of cell cycleGO:0051726520.019
nucleoside monophosphate catabolic processGO:000912540.019
regulation of gtp catabolic processGO:003312420.019
cellular protein complex assemblyGO:0043623190.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
stem cell fate commitmentGO:004886510.019
meiosis iGO:000712710.019
response to nutrientGO:000758430.019
vasculature developmentGO:00019442780.019
rna metabolic processGO:00160702190.019
Human
negative regulation of cell deathGO:0060548600.019
synaptic vesicle localizationGO:009747910.019
response to drugGO:004249330.019
regulation of response to extracellular stimulusGO:003210410.019
regulation of multicellular organismal developmentGO:20000262230.019
regulation of organelle assemblyGO:190211540.019
protein polymerizationGO:005125840.019
regulation of catalytic activityGO:0050790550.018
regulation of cell cycle processGO:0010564200.018
spindle assemblyGO:005122520.018
lymphocyte proliferationGO:004665110.018
positive regulation of map kinase activityGO:004340630.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
neuron remodelingGO:001632210.018
negative regulation of phosphate metabolic processGO:0045936130.018
mitotic cell cycle processGO:1903047480.018
stem cell proliferationGO:007208940.018
regulation of autophagyGO:001050630.018
response to hydrogen peroxideGO:004254230.018
single organism cellular localizationGO:1902580460.018
cellular nitrogen compound metabolic processGO:00346412900.018
Human
regulation of cellular ketone metabolic processGO:001056570.017
cell cycle g1 s phase transitionGO:004484310.017
catabolic processGO:0009056320.017
signal transduction in absence of ligandGO:003803410.017
transmembrane transportGO:00550851200.017
cellular response to extracellular stimulusGO:003166820.017
protein dephosphorylationGO:000647030.017
muscle structure developmentGO:00610611960.017
negative regulation of nuclear divisionGO:005178430.017
cellular amino acid metabolic processGO:000652070.017
regulation of apoptotic processGO:0042981980.017
regulation of multicellular organism growthGO:004001440.017
response to bacteriumGO:0009617580.017
regulation of transportGO:0051049450.017
protein complex disassemblyGO:004324110.017
oocyte anterior posterior axis specificationGO:000731440.016
regulation of nitrogen compound metabolic processGO:00511712510.016
cellular response to external stimulusGO:007149620.016
actin filament based processGO:0030029640.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
mrna export from nucleusGO:000640610.016
protein polyubiquitinationGO:000020940.016
determination of bilateral symmetryGO:00098552040.016
cellular component morphogenesisGO:00329893360.016
cell cycleGO:0007049930.016
response to monosaccharideGO:003428430.016
specification of symmetryGO:00097992040.016
nucleic acid templated transcriptionGO:00976591810.016
multi organism processGO:00517041340.016
negative regulation of programmed cell deathGO:0043069580.016
positive regulation of secretion by cellGO:190353210.016
regulation of cellular biosynthetic processGO:00313262450.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
regulation of purine nucleotide catabolic processGO:003312120.016
locomotor rhythmGO:004547530.016
development of primary female sexual characteristicsGO:004654540.016
regulation of cell activationGO:005086510.016
regulation of cell deathGO:00109411030.016
adherens junction organizationGO:003433240.016
regulation of synapse organizationGO:005080730.015
guanosine containing compound catabolic processGO:190106920.015
g1 s transition of mitotic cell cycleGO:000008210.015
muscle cell differentiationGO:00426921390.015
peptidyl serine phosphorylationGO:001810510.015
defense responseGO:0006952470.015
atp catabolic processGO:000620040.015
positive regulation of jnk cascadeGO:004633030.015
autophagyGO:000691440.015
protein modification by small protein removalGO:007064610.015
Human
cellular response to nutrient levelsGO:003166920.015
gastrulation with mouth forming secondGO:0001702440.015
maternal determination of anterior posterior axis embryoGO:000835840.015
regulation of protein polymerizationGO:003227120.015
guanosine containing compound metabolic processGO:190106840.015
regulation of macromolecule biosynthetic processGO:00105562250.015
single organism localizationGO:19025782250.015
organelle assemblyGO:00709251100.015
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of cellular amine metabolic processGO:003323800.015
peptidyl serine modificationGO:001820920.015
heterocycle metabolic processGO:00464832900.015
Human
developmental maturationGO:0021700340.015
positive regulation of secretionGO:005104710.015
cellular response to endogenous stimulusGO:0071495680.015
small molecule metabolic processGO:0044281770.014
proteolysisGO:0006508380.014
Human
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
regulation of protein phosphorylationGO:0001932180.014
regulation of dendrite developmentGO:005077330.014
growthGO:00400071740.014
response to carbohydrateGO:000974330.014
cellular ketone metabolic processGO:0042180110.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
positive regulation of nervous system developmentGO:0051962250.014
long chain fatty acid metabolic processGO:000167610.014
response to light stimulusGO:0009416460.014
macromolecule localizationGO:0033036540.014
Human
negative regulation of molecular functionGO:0044092230.014
response to organic substanceGO:00100331530.014
mitotic cell cycle checkpointGO:000709350.014
organic substance catabolic processGO:1901575280.014
cell matrix adhesionGO:000716040.014
anterior posterior pattern specificationGO:00099521520.014
carbohydrate biosynthetic processGO:001605110.014
cytoplasm organizationGO:000702840.014
response to oxygen containing compoundGO:1901700550.014
compound eye developmentGO:004874920.014
multi organism cellular processGO:004476420.014
neuron projection morphogenesisGO:00488121610.014
cellular response to stressGO:0033554620.014
macromolecular complex disassemblyGO:003298410.014
ion transportGO:00068111140.014
regulation of dendrite morphogenesisGO:004881430.014
response to woundingGO:00096111160.014
epithelial tube morphogenesisGO:00605621480.014
cellular macromolecular complex assemblyGO:0034622240.014
Human
cytoplasmic transportGO:0016482110.013
carboxylic acid metabolic processGO:0019752220.013
regulation of phosphorus metabolic processGO:0051174430.013
regulation of protein modification processGO:0031399290.013
Human
regulation of proteolysisGO:0030162240.013
regulation of response to stressGO:0080134360.013
regulation of stem cell differentiationGO:200073640.013
skeletal system developmentGO:00015011810.013
regulation of programmed cell deathGO:00430671010.013
rna localizationGO:000640340.013
positive regulation of signal transductionGO:0009967560.013
regulation of reproductive processGO:200024140.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
actin polymerization or depolymerizationGO:000815420.013
blood vessel morphogenesisGO:00485142160.013
defense response to virusGO:0051607100.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
positive regulation of cell adhesionGO:004578510.013
negative regulation of defense responseGO:003134820.013
cellular response to starvationGO:000926710.013
interspecies interaction between organismsGO:004441940.013
stem cell divisionGO:001714510.013
regulation of synapse assemblyGO:005196330.013
regulation of carbohydrate metabolic processGO:000610940.013
organism emergence from protective structureGO:007168440.013
spermatid developmentGO:000728620.013
response to hexoseGO:000974630.013
organic cyclic compound biosynthetic processGO:19013622230.012
stem cell differentiationGO:00488631170.012
negative regulation of cellular metabolic processGO:0031324770.012
Human
regulation of cellular amino acid metabolic processGO:000652100.012
regulation of gtpase activityGO:004308720.012
establishment of localization in cellGO:0051649770.012
negative regulation of jnk cascadeGO:004632910.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
response to glucoseGO:000974930.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
actin filament polymerizationGO:003004120.012
histone h3 k4 methylationGO:005156820.012
embryonic organ developmentGO:00485683810.012
pole plasm assemblyGO:000731540.012
oocyte maturationGO:000155640.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
toxin transportGO:190199820.012
macromolecular complex assemblyGO:0065003350.012
Human
negative regulation of cellular protein metabolic processGO:0032269160.012
Human
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
apoptotic process involved in morphogenesisGO:006056120.012
aromatic compound biosynthetic processGO:00194382170.012
positive regulation of dna metabolic processGO:005105410.012
actin cytoskeleton organizationGO:0030036630.012
organic acid metabolic processGO:0006082310.012
regulation of protein bindingGO:004339330.012
regulation of transcription dna templatedGO:00063552130.012
cell substrate junction assemblyGO:000704420.012
negative regulation of catalytic activityGO:0043086210.012
mitotic sister chromatid segregationGO:000007060.012
negative regulation of intracellular signal transductionGO:1902532220.012
regulation of response to nutrient levelsGO:003210710.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
head developmentGO:00603223030.012
positive regulation of nucleotide catabolic processGO:003081310.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
tissue remodelingGO:004877140.011
adherens junction assemblyGO:003433310.011
tissue regenerationGO:0042246740.011
cellular macromolecule localizationGO:0070727210.011
Human
ras protein signal transductionGO:000726570.011
rna biosynthetic processGO:00327741810.011
nucleobase containing compound biosynthetic processGO:00346542050.011
b cell activationGO:004211320.011
negative regulation of cytokine productionGO:000181810.011
protein localizationGO:0008104400.011
Human
positive regulation of chromatin modificationGO:190331010.011
chordate embryonic developmentGO:00430092710.011
negative regulation of mitotic cell cycleGO:0045930110.011
protein k63 linked ubiquitinationGO:007053420.011
oxoacid metabolic processGO:0043436310.011
regulation of rna metabolic processGO:00512522240.011
transcription dna templatedGO:00063511810.011
negative regulation of cellular catabolic processGO:003133030.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
wnt signaling pathwayGO:0016055800.011
negative regulation of protein processingGO:0010955100.011
segmentationGO:0035282970.011
negative regulation of intracellular protein transportGO:009031730.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
carbohydrate homeostasisGO:003350010.011
negative regulation of synapse assemblyGO:005196420.011
protein depolymerizationGO:005126110.011
regulation of alternative mrna splicing via spliceosomeGO:000038110.011
production of molecular mediator of immune responseGO:000244020.010
purine nucleoside monophosphate catabolic processGO:000912840.010
mitotic cell cycle phase transitionGO:004477290.010
response to inorganic substanceGO:0010035380.010
sensory organ developmentGO:00074233930.010
regulation of neurogenesisGO:0050767870.010
cellular response to organic substanceGO:00713101050.010
establishment of synaptic vesicle localizationGO:009748010.010
gtp catabolic processGO:000618420.010
cell cycle phase transitionGO:004477090.010
taxisGO:00423301090.010
chemotaxisGO:00069351040.010
purine ribonucleoside monophosphate catabolic processGO:000916940.010
negative regulation of mitotic cell cycle phase transitionGO:190199150.010
response to radiationGO:0009314510.010
hatchingGO:003518840.010
mesenchyme developmentGO:00604851270.010
camera type eye developmentGO:00430102220.010
heterocycle biosynthetic processGO:00181302150.010
developmental programmed cell deathGO:001062340.010
positive regulation of chromosome organizationGO:200125210.010
macromolecule catabolic processGO:0009057150.010
regulation of erk1 and erk2 cascadeGO:007037240.010
positive regulation of cytoskeleton organizationGO:005149530.010
positive regulation of gtpase activityGO:004354710.010
regulation of translational initiationGO:000644610.010
defense response to other organismGO:0098542330.010
regulation of carbohydrate biosynthetic processGO:004325510.010

usp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
musculoskeletal system diseaseDOID:1700.013
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.013
nervous system diseaseDOID:86300.010