Danio rerio

25 known processes

bad

BCL2-antagonist of cell death

(Aliases: wu:fa96d04,wu:fa01b12)

bad biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.420
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.288
Mouse
larval developmentGO:000216420.258
regulation of metabolic processGO:00192223590.250
Mouse
positive regulation of cell deathGO:0010942290.245
regulation of cell deathGO:00109411030.216
positive regulation of apoptotic processGO:0043065290.201
membrane fusionGO:006102520.128
cell deathGO:00082191210.126
organelle fusionGO:004828430.117
transmembrane transportGO:00550851200.116
regulation of mitochondrion organizationGO:001082110.110
deathGO:00162651210.109
regulation of cysteine type endopeptidase activityGO:2000116210.108
Mouse
regulation of programmed cell deathGO:00430671010.105
phosphorus metabolic processGO:00067931090.098
Mouse
positive regulation of programmed cell deathGO:0043068290.097
positive regulation of cysteine type endopeptidase activityGO:2001056100.095
Mouse
negative regulation of mitosisGO:004583930.092
apoptotic processGO:00069151160.088
regulation of endopeptidase activityGO:0052548230.085
Mouse
organic cyclic compound metabolic processGO:19013603010.084
Mouse
regulation of peptidase activityGO:0052547230.080
Mouse
cellular response to external stimulusGO:007149620.079
positive regulation of cellular processGO:00485222010.079
response to vitamin b3GO:003355220.075
regulation of nucleotide catabolic processGO:003081120.075
regulation of apoptotic processGO:0042981980.075
regulation of primary metabolic processGO:00800903110.065
Mouse
negative regulation of nuclear divisionGO:005178430.064
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.063
positive regulation of purine nucleotide catabolic processGO:003312310.063
fertilizationGO:000956630.063
response to amphetamineGO:000197510.057
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.056
regulation of metal ion transportGO:001095940.054
regulation of biological qualityGO:00650082630.052
Mouse
single organism membrane fusionGO:004480120.048
small molecule metabolic processGO:0044281770.047
Mouse
angiogenesisGO:00015251580.047
response to nutrientGO:000758430.046
organonitrogen compound metabolic processGO:1901564740.045
Mouse
negative regulation of catalytic activityGO:0043086210.045
cellular response to oxygen levelsGO:007145310.044
apoptotic process involved in developmentGO:190274220.044
chordate embryonic developmentGO:00430092710.043
cellular amine metabolic processGO:004410620.043
regulation of cellular amine metabolic processGO:003323800.042
guanosine containing compound catabolic processGO:190106920.042
apoptotic process involved in morphogenesisGO:006056120.041
cellular response to hypoxiaGO:007145610.041
negative regulation of macromolecule metabolic processGO:0010605760.040
regulation of gtp catabolic processGO:003312420.040
maintenance of locationGO:005123540.039
regulation of blood pressureGO:000821710.039
regulation of extrinsic apoptotic signaling pathwayGO:200123630.039
guanosine containing compound metabolic processGO:190106840.038
lipid catabolic processGO:001604240.037
amine metabolic processGO:000930820.037
positive regulation of peptidase activityGO:0010952100.036
Mouse
multi organism cellular processGO:004476420.036
Mouse
positive regulation of gtpase activityGO:004354710.036
regionalizationGO:00030022740.035
lipid homeostasisGO:005508830.035
positive regulation of biological processGO:00485182530.035
triglyceride homeostasisGO:007032820.035
cellular nitrogen compound metabolic processGO:00346412900.034
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.034
calcium ion importGO:007050940.034
cell death in response to oxidative stressGO:003647320.034
cellular response to organic cyclic compoundGO:0071407380.034
zymogen activationGO:003163830.033
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.032
gas transportGO:001566930.032
regulation of cellular metabolic processGO:00313233200.032
Mouse
phosphate containing compound metabolic processGO:00067961080.031
Mouse
mitochondrion organizationGO:000700540.031
Mouse
negative regulation of gene expressionGO:0010629650.031
biosynthetic processGO:00090582940.030
proteolysisGO:0006508380.030
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.030
positive regulation of gtp catabolic processGO:003312610.030
lipid storageGO:001991510.029
killing of cells of other organismGO:003164010.029
Mouse
gtp catabolic processGO:000618420.029
positive regulation of cellular metabolic processGO:0031325940.029
Mouse
negative regulation of protein serine threonine kinase activityGO:007190120.028
negative regulation of cysteine type endopeptidase activityGO:200011780.028
regulation of lipid catabolic processGO:005099420.028
negative regulation of protein phosphorylationGO:000193340.028
endocrine system developmentGO:0035270650.027
Mouse
reactive nitrogen species metabolic processGO:200105700.027
positive regulation of transportGO:005105020.027
Mouse
oxoacid metabolic processGO:0043436310.027
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.027
negative regulation of cell cycleGO:0045786140.026
response to steroid hormoneGO:0048545350.026
response to lipidGO:0033993600.026
Mouse
organic substance biosynthetic processGO:19015762890.026
programmed cell deathGO:00125011190.026
gtp metabolic processGO:004603940.026
establishment of localizationGO:00512342440.025
Mouse
regulation of calcium ion transportGO:005192420.025
acylglycerol homeostasisGO:005509020.025
sensory perception of chemical stimulusGO:000760630.025
reactive oxygen species biosynthetic processGO:190340910.025
regulation of cellular biosynthetic processGO:00313262450.025
peptidyl serine phosphorylationGO:001810510.025
heterocycle metabolic processGO:00464832900.025
Mouse
positive regulation of apoptotic signaling pathwayGO:200123510.024
regulation of catalytic activityGO:0050790550.024
Mouse
transportGO:00068102200.024
Mouse
positive regulation of nucleoside metabolic processGO:004597910.024
cellular macromolecule metabolic processGO:00442603910.024
Mouse
negative regulation of metabolic processGO:0009892860.024
developmental programmed cell deathGO:001062340.024
cellular response to chemical stimulusGO:00708871570.023
cellular aldehyde metabolic processGO:000608140.023
response to hexoseGO:000974630.023
Mouse
cation transportGO:0006812810.023
negative regulation of kinase activityGO:003367340.023
homeostatic processGO:00425921420.023
Mouse
cellular response to decreased oxygen levelsGO:003629410.023
reactive oxygen species metabolic processGO:007259360.023
cell migrationGO:00164772370.023
negative regulation of proteolysisGO:0045861100.022
agingGO:000756820.022
carboxylic acid metabolic processGO:0019752220.021
regulation of phGO:000688530.021
stem cell differentiationGO:00488631170.021
protein localization to nucleusGO:003450430.021
regulation of tube sizeGO:003515020.021
regulation of phosphate metabolic processGO:0019220430.021
Mouse
nitric oxide biosynthetic processGO:000680920.020
regulation of nucleoside metabolic processGO:000911820.020
regulation of organ growthGO:004662030.020
epithelium migrationGO:0090132250.020
cellular lipid metabolic processGO:0044255360.020
single organism metabolic processGO:00447102170.020
Mouse
synaptic vesicle localizationGO:009747910.020
stem cell developmentGO:0048864820.020
positive regulation of cellular catabolic processGO:003133130.019
negative regulation of cell communicationGO:0010648960.019
locomotionGO:00400113130.019
stem cell maintenanceGO:001982740.019
cellular biogenic amine metabolic processGO:000657620.019
negative regulation of tor signalingGO:003200720.019
negative regulation of cellular metabolic processGO:0031324770.019
response to uvGO:000941130.019
nitrogen compound metabolic processGO:00068073190.019
Mouse
regulation of synaptic plasticityGO:004816710.019
negative regulation of programmed cell deathGO:0043069580.018
Mouse
hindbrain formationGO:002157630.018
regulation of gtpase activityGO:004308720.018
chemical homeostasisGO:0048878490.018
Mouse
peptidyl serine modificationGO:001820920.018
regulation of purine nucleotide catabolic processGO:003312120.018
positive regulation of catabolic processGO:000989640.018
nucleobase containing small molecule metabolic processGO:0055086320.018
Mouse
regulation of phosphorus metabolic processGO:0051174430.018
Mouse
cell proliferationGO:0008283800.018
Mouse
regulation of protein catabolic processGO:004217610.017
regulation of macromolecule metabolic processGO:00602553170.017
Mouse
heterocycle biosynthetic processGO:00181302150.017
mitotic dna integrity checkpointGO:004477440.017
tissue remodelingGO:004877140.017
blood vessel developmentGO:00015682460.017
regulation of hormone secretionGO:004688320.017
Mouse
synaptic vesicle transportGO:004848910.017
gastrulationGO:00073692080.017
response to oxygen containing compoundGO:1901700550.017
Mouse
regulation of cellular protein metabolic processGO:0032268520.017
Mouse
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.017
Mouse
germ line stem cell divisionGO:004207810.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.017
negative regulation of cellular processGO:00485232830.017
Mouse
negative regulation of protein kinase activityGO:000646940.017
negative regulation of apoptotic processGO:0043066550.017
Mouse
regulation of developmental processGO:00507932470.016
Mouse
nuclear importGO:005117030.016
cellular biosynthetic processGO:00442492860.016
cell projection organizationGO:00300302840.016
response to vitaminGO:003327330.016
response to hormoneGO:0009725480.016
cytokinesisGO:000091030.016
cellular response to extracellular stimulusGO:003166820.016
signal transductionGO:00071654550.016
Mouse
embryonic appendage morphogenesisGO:0035113300.016
cation homeostasisGO:0055080330.015
disruption of cells of other organismGO:004436410.015
Mouse
organelle organizationGO:00069962270.015
Mouse
fat soluble vitamin biosynthetic processGO:004236220.015
regulation of protein localization to nucleusGO:190018020.015
nucleoside monophosphate catabolic processGO:000912540.015
single organism biosynthetic processGO:0044711710.015
organic acid metabolic processGO:0006082310.015
neuron neuron synaptic transmissionGO:000727010.015
cardiac muscle cell differentiationGO:0055007300.015
golgi vesicle transportGO:004819330.015
negative regulation of protein maturationGO:1903318100.015
killing of cells in other organism involved in symbiotic interactionGO:005188310.015
Mouse
nucleocytoplasmic transportGO:000691340.015
response to metal ionGO:0010038340.015
cellular ketone metabolic processGO:0042180110.015
aromatic compound biosynthetic processGO:00194382170.015
establishment of synaptic vesicle localizationGO:009748010.014
viral processGO:001603210.014
Mouse
response to inorganic substanceGO:0010035380.014
regulation of blood vessel sizeGO:005088020.014
response to alkaloidGO:004327920.014
diterpenoid metabolic processGO:0016101150.014
cellular response to radiationGO:007147840.014
segmentationGO:0035282970.014
anterior posterior pattern specificationGO:00099521520.014
regulation of rna biosynthetic processGO:20011412130.014
negative regulation of response to stimulusGO:00485851040.014
negative regulation of dna metabolic processGO:005105340.014
negative regulation of protein metabolic processGO:0051248160.014
cellular response to organic substanceGO:00713101050.014
autophagyGO:000691440.014
regulation of anatomical structure morphogenesisGO:00226031300.013
response to cadmium ionGO:0046686140.013
negative regulation of catabolic processGO:000989530.013
positive regulation of cell cycleGO:004578730.013
modification dependent macromolecule catabolic processGO:004363230.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
spindle assemblyGO:005122520.013
negative regulation of protein localization to nucleusGO:190018120.013
nucleobase containing compound metabolic processGO:00061392740.013
Mouse
regulation of gene expressionGO:00104682650.013
regulation of cellular amino acid metabolic processGO:000652100.013
embryonic limb morphogenesisGO:003032620.013
sensory organ developmentGO:00074233930.013
response to amineGO:001407510.013
regulation of autophagyGO:001050630.013
tube formationGO:0035148250.013
digestive system developmentGO:00551232890.013
regulation of sodium ion transportGO:000202820.012
regulation of cytokine productionGO:000181730.012
vestibular receptor cell differentiationGO:006011430.012
negative regulation of dna replicationGO:000815620.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of synapse organizationGO:005080730.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
Mouse
fatty acid elongation unsaturated fatty acidGO:001936810.012
protein importGO:001703830.012
sodium ion importGO:009736930.012
blood vessel morphogenesisGO:00485142160.012
regulation of molecular functionGO:0065009700.012
Mouse
negative regulation of cellular protein metabolic processGO:0032269160.012
thyroid gland developmentGO:0030878120.012
positive regulation of nucleotide catabolic processGO:003081310.012
positive regulation of neuron deathGO:190121610.012
protein metabolic processGO:00195381830.012
Mouse
alcohol biosynthetic processGO:004616520.012
muscle hypertrophyGO:001489620.012
cellular response to nutrient levelsGO:003166920.011
negative regulation of cytoplasmic transportGO:190365020.011
phosphorylationGO:0016310690.011
Mouse
digestive tract developmentGO:00485652650.011
modification of morphology or physiology of other organismGO:003582140.011
Mouse
positive regulation of catalytic activityGO:0043085250.011
Mouse
regulation of oxidative stress induced cell deathGO:190320120.011
epithelial cell differentiationGO:00308551160.011
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.011
lymphocyte proliferationGO:004665110.011
small molecule catabolic processGO:004428230.011
macromolecule biosynthetic processGO:00090592270.011
nitric oxide metabolic processGO:004620920.011
cellular response to lipidGO:0071396390.011
Mouse
cofactor metabolic processGO:0051186150.011
post golgi vesicle mediated transportGO:000689210.011
mrna 3 end processingGO:003112420.011
regulation of cellular protein catabolic processGO:190336210.011
single organism transportGO:00447652060.011
Mouse
negative regulation of peptidase activityGO:0010466100.011
mitotic cytokinesisGO:000028130.011
germ line stem cell maintenanceGO:003071820.011
response to glucoseGO:000974930.011
Mouse
gland developmentGO:00487321430.011
localization of cellGO:00516742440.011
membrane lipid metabolic processGO:0006643100.011
morphogenesis of an epitheliumGO:00020093330.010
negative regulation of small gtpase mediated signal transductionGO:005105810.010
cellular lipid catabolic processGO:004424230.010
organic cyclic compound biosynthetic processGO:19013622230.010
response to stressGO:00069502630.010
Mouse
adult behaviorGO:003053420.010
brain developmentGO:00074202930.010
lipid metabolic processGO:0006629520.010
cellular response to starvationGO:000926710.010
rhombomere 6 developmentGO:002157240.010
gene silencing by mirnaGO:003519530.010
negative regulation of cell deathGO:0060548600.010
Mouse
cellular response to stressGO:0033554620.010
Mouse
regulation of reproductive processGO:200024140.010

bad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
disease of anatomical entityDOID:700.016
musculoskeletal system diseaseDOID:1700.014
endocrine system diseaseDOID:2800.014
cardiovascular system diseaseDOID:128700.011