Danio rerio

5 known processes

lta4h

leukotriene A4 hydrolase

(Aliases: zgc:85809)

lta4h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular extravasationGO:000269310.687
larval developmentGO:000216420.255
cellular extravasationGO:004512310.183
regulation of immune system processGO:0002682340.155
regulation of cell activationGO:005086510.150
regulation of metabolic processGO:00192223590.149
superoxide metabolic processGO:000680120.143
agingGO:000756820.129
regulation of multicellular organismal processGO:00512392770.119
taxisGO:00423301090.113
regulation of wound healingGO:006104120.106
generation of neuronsGO:00486993850.105
positive regulation of cellular component biogenesisGO:004408930.100
regulation of primary metabolic processGO:00800903110.096
response to bacteriumGO:0009617580.095
response to chemicalGO:00422213200.095
Rat
regulation of signalingGO:00230512350.093
signal transductionGO:00071654550.090
regulation of cellular extravasationGO:000269110.090
multicellular organismal homeostasisGO:0048871290.090
positive regulation of cytokine productionGO:000181920.084
guanosine containing compound metabolic processGO:190106840.082
response to stressGO:00069502630.081
neutrophil migrationGO:1990266100.078
positive regulation of response to external stimulusGO:003210390.078
striated muscle cell developmentGO:00550021080.077
regulation of biological qualityGO:00650082630.077
regulation of transcription dna templatedGO:00063552130.076
regulation of response to external stimulusGO:0032101310.076
cortical actin cytoskeleton organizationGO:003086610.076
cellular nitrogen compound metabolic processGO:00346412900.074
guanosine containing compound catabolic processGO:190106920.073
lipid storageGO:001991510.073
neutrophil mediated immunityGO:000244610.072
defense response to bacteriumGO:0042742220.072
response to external stimulusGO:00096052640.072
positive regulation of cellular catabolic processGO:003133130.068
positive regulation of catabolic processGO:000989640.068
gtp metabolic processGO:004603940.067
phagocytosisGO:000690930.067
response to biotic stimulusGO:0009607970.066
regulation of multicellular organismal developmentGO:20000262230.064
gtp catabolic processGO:000618420.063
lamellipodium assemblyGO:003003210.060
regulation of cellular biosynthetic processGO:00313262450.058
tissue remodelingGO:004877140.057
response to other organismGO:0051707970.057
regulation of signal transductionGO:00099662250.057
response to external biotic stimulusGO:0043207970.057
cellular nitrogen compound biosynthetic processGO:00442712180.056
adherens junction organizationGO:003433240.056
gene expressionGO:00104672520.056
regulation of macromolecule metabolic processGO:00602553170.055
regulation of i kappab kinase nf kappab signalingGO:004312240.055
system processGO:00030081850.055
regulation of protein complex assemblyGO:004325430.054
positive regulation of wound healingGO:009030310.054
cell migrationGO:00164772370.052
regulation of developmental processGO:00507932470.052
regulation of inflammatory responseGO:005072720.051
transcription dna templatedGO:00063511810.051
negative regulation of biological processGO:00485193040.051
immune system processGO:00023762410.050
positive regulation of i kappab kinase nf kappab signalingGO:004312330.050
tube morphogenesisGO:00352393490.050
positive regulation of cell activationGO:005086710.049
neutrophil chemotaxisGO:0030593100.049
regulation of circadian rhythmGO:004275240.049
neuron developmentGO:00486662620.049
positive regulation of cell adhesionGO:004578510.049
positive regulation of biological processGO:00485182530.048
small gtpase mediated signal transductionGO:000726480.048
intracellular mrna localizationGO:000829810.048
regulation of cytokine productionGO:000181730.047
granulocyte migrationGO:0097530110.047
eye developmentGO:00016542770.046
single organism localizationGO:19025782250.046
regulation of cellular macromolecule biosynthetic processGO:20001122220.046
myeloid leukocyte migrationGO:0097529120.045
chemotaxisGO:00069351040.045
locomotionGO:00400113130.045
neuron neuron synaptic transmissionGO:000727010.045
positive regulation of cellular processGO:00485222010.044
regionalizationGO:00030022740.044
symbiosis encompassing mutualism through parasitismGO:004440340.044
regulation of response to stimulusGO:00485832690.043
positive regulation of inflammatory responseGO:005072910.043
cellular component movementGO:00069283350.043
actin cytoskeleton organizationGO:0030036630.043
nucleic acid templated transcriptionGO:00976591810.043
regulation of synapse organizationGO:005080730.043
regulation of synaptic plasticityGO:004816710.042
regulation of cell shapeGO:000836010.042
regulation of biosynthetic processGO:00098892500.042
g protein coupled receptor signaling pathwayGO:0007186740.041
digestive tract morphogenesisGO:00485462310.041
response to woundingGO:00096111160.041
eye morphogenesisGO:00485921440.041
response to amino acidGO:004320020.041
actin filament polymerizationGO:003004120.040
cellular aromatic compound metabolic processGO:00067252950.040
transportGO:00068102200.040
cognitionGO:005089010.040
regulation of protein catabolic processGO:004217610.039
cellular macromolecule metabolic processGO:00442603910.039
smooth muscle contractionGO:000693920.038
rna metabolic processGO:00160702190.038
lamellipodium organizationGO:009758110.038
defense response to other organismGO:0098542330.038
biosynthetic processGO:00090582940.038
cellular component morphogenesisGO:00329893360.038
vasculature developmentGO:00019442780.038
positive regulation of neutrophil extravasationGO:200039110.037
leukocyte chemotaxisGO:0030595120.037
cellular response to chemical stimulusGO:00708871570.037
ameboidal type cell migrationGO:00016671430.037
establishment of protein localization to plasma membraneGO:009000210.036
multi organism processGO:00517041340.036
positive regulation of response to stimulusGO:0048584800.036
positive regulation of apoptotic signaling pathwayGO:200123510.036
cell substrate adhesionGO:003158940.036
regulation of gene expressionGO:00104682650.035
membrane fusionGO:006102520.035
regulation of cell communicationGO:00106462320.035
single organism metabolic processGO:00447102170.035
Rat
localization of cellGO:00516742440.035
establishment of localizationGO:00512342440.035
stem cell maintenanceGO:001982740.035
cell motilityGO:00488702440.034
muscle cell developmentGO:00550011150.034
protein polymerizationGO:005125840.034
regulation of establishment or maintenance of cell polarityGO:003287820.034
central nervous system developmentGO:00074173870.034
organic substance biosynthetic processGO:19015762890.034
amino acid transportGO:000686520.034
oxoacid metabolic processGO:0043436310.033
Rat
regulation of macromolecule biosynthetic processGO:00105562250.033
regulation of multicellular organism growthGO:004001440.033
positive regulation of protein complex assemblyGO:003133420.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
positive regulation of molecular functionGO:0044093330.033
actin polymerization or depolymerizationGO:000815420.033
regulation of cellular amine metabolic processGO:003323800.033
nucleobase containing compound biosynthetic processGO:00346542050.033
collagen metabolic processGO:003296320.033
gastrulationGO:00073692080.032
maintenance of locationGO:005123540.032
regulation of synapse assemblyGO:005196330.032
response to organic substanceGO:00100331530.032
Rat
growthGO:00400071740.032
phosphate containing compound metabolic processGO:00067961080.032
cellular biosynthetic processGO:00442492860.031
angiogenesisGO:00015251580.031
muscle structure developmentGO:00610611960.031
maternal determination of anterior posterior axis embryoGO:000835840.031
response to alkaloidGO:004327920.031
protein metabolic processGO:00195381830.031
myotube differentiationGO:0014902450.030
cellular amino acid metabolic processGO:000652070.030
regulation of cellular carbohydrate metabolic processGO:001067540.030
regulation of cellular metabolic processGO:00313233200.030
cellular component assemblyGO:00226071700.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
muscle organ developmentGO:00075171010.029
protein targeting to membraneGO:000661210.029
single organism cellular localizationGO:1902580460.029
cellular protein catabolic processGO:004425740.029
regulation of synaptic growth at neuromuscular junctionGO:000858210.029
regulation of nitrogen compound metabolic processGO:00511712510.029
phagocytosis engulfmentGO:000691110.029
regulation of protein polymerizationGO:003227120.029
protein localizationGO:0008104400.029
regulation of cell projection assemblyGO:006049140.029
carbohydrate derivative metabolic processGO:1901135610.028
rna localizationGO:000640340.028
i kappab kinase nf kappab signalingGO:000724940.028
nucleic acid metabolic processGO:00903042440.028
cellular macromolecule biosynthetic processGO:00346452240.028
positive regulation of cellular amino acid metabolic processGO:004576400.028
aromatic compound biosynthetic processGO:00194382170.028
striated muscle cell differentiationGO:00511461290.028
rna biosynthetic processGO:00327741810.028
digestive tract developmentGO:00485652650.028
regulation of muscle contractionGO:000693730.028
wound healingGO:0042060900.028
morphogenesis of an epitheliumGO:00020093330.028
embryonic organ developmentGO:00485683810.028
interspecies interaction between organismsGO:004441940.028
establishment of protein localization to organelleGO:007259440.028
nucleobase containing compound metabolic processGO:00061392740.027
cellular carbohydrate metabolic processGO:004426240.027
regulation of rna biosynthetic processGO:20011412130.027
muscle cell differentiationGO:00426921390.027
cell proliferationGO:0008283800.027
innate immune responseGO:0045087130.027
cortical cytoskeleton organizationGO:003086510.027
regulation of cell motilityGO:2000145460.027
cell surface receptor signaling pathwayGO:00071663250.026
single organism transportGO:00447652060.026
heterocycle metabolic processGO:00464832900.026
spermatid developmentGO:000728620.026
regulation of phosphorus metabolic processGO:0051174430.026
membrane organizationGO:0061024210.026
regulation of localizationGO:00328791040.026
cell morphogenesisGO:00009022890.026
muscle fiber developmentGO:0048747520.026
regulation of metal ion transportGO:001095940.026
activation of mapk activityGO:000018730.026
positive regulation of secretion by cellGO:190353210.026
regulation of establishment of protein localizationGO:007020140.025
small molecule metabolic processGO:0044281770.025
Rat
neuron differentiationGO:00301823530.025
cellular component disassemblyGO:002241110.025
nitrogen compound metabolic processGO:00068073190.025
regulation of locomotionGO:0040012550.025
phosphorus metabolic processGO:00067931090.025
cellular component maintenanceGO:004395430.025
regulation of cellular ketone metabolic processGO:001056570.025
negative regulation of protein phosphorylationGO:000193340.025
regulation of leukocyte migrationGO:000268580.025
multicellular organism growthGO:003526440.025
positive regulation of protein kinase b signalingGO:005189710.024
regulation of chemotaxisGO:0050920180.024
carboxylic acid metabolic processGO:0019752220.024
Rat
macromolecule biosynthetic processGO:00090592270.024
reactive oxygen species biosynthetic processGO:190340910.024
multicellular organismal response to stressGO:003355520.024
cellular response to external stimulusGO:007149620.024
cellular aldehyde metabolic processGO:000608140.024
multicellular organismal macromolecule metabolic processGO:004425920.024
amine metabolic processGO:000930820.024
respiratory burstGO:004573020.024
protein localization to plasma membraneGO:007265910.023
organonitrogen compound metabolic processGO:1901564740.023
regulation of nucleotide catabolic processGO:003081120.023
homeostasis of number of cells within a tissueGO:004887340.023
response to hydrogen peroxideGO:004254230.023
hydrogen peroxide metabolic processGO:004274320.023
blood vessel morphogenesisGO:00485142160.023
macromolecular complex disassemblyGO:003298410.023
regulation of cellular component movementGO:0051270550.023
negative regulation of cellular processGO:00485232830.022
positive regulation of leukocyte migrationGO:000268720.022
regulation of rho protein signal transductionGO:003502320.022
dicarboxylic acid transportGO:000683510.022
positive regulation of map kinase activityGO:004340630.022
multicellular organismal metabolic processGO:004423620.022
protein import into nucleusGO:000660630.022
stem cell proliferationGO:007208940.022
regulation of dendrite developmentGO:005077330.022
homeostasis of number of cellsGO:0048872620.022
positive regulation of gtp catabolic processGO:003312610.021
neural crest cell developmentGO:0014032620.021
protein complex disassemblyGO:004324110.021
modification dependent macromolecule catabolic processGO:004363230.021
purine containing compound biosynthetic processGO:0072522200.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
cytoskeleton organizationGO:0007010960.021
positive regulation of metabolic processGO:00098931080.021
pole plasm assemblyGO:000731540.021
regulation of cell substrate adhesionGO:001081010.021
regulation of cell migrationGO:0030334400.021
single organism membrane fusionGO:004480120.021
regulation of cell developmentGO:00602841000.021
retina development in camera type eyeGO:00600411460.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
stem cell developmentGO:0048864820.020
defense responseGO:0006952470.020
lymph vessel morphogenesisGO:0036303250.020
programmed cell deathGO:00125011190.020
regulation of cell morphogenesisGO:0022604420.020
neuron projection developmentGO:00311751800.020
regulation of cellular component organizationGO:0051128860.020
regulation of rna metabolic processGO:00512522240.020
tissue homeostasisGO:0001894250.020
regulation of reproductive processGO:200024140.019
digestive system developmentGO:00551232890.019
lymph vessel developmentGO:0001945270.019
organelle fusionGO:004828430.019
proteasomal protein catabolic processGO:001049820.019
purine nucleotide metabolic processGO:0006163270.019
membrane invaginationGO:001032410.019
embryo development ending in birth or egg hatchingGO:00097922710.019
mononuclear cell proliferationGO:003294310.019
regulation of neutrophil migrationGO:190262260.019
cell projection morphogenesisGO:00488582440.019
ras protein signal transductionGO:000726570.019
leukocyte mediated cytotoxicityGO:000190910.019
positive regulation of nucleoside metabolic processGO:004597910.019
regulation of purine nucleotide catabolic processGO:003312120.019
axon developmentGO:00615641660.019
regulation of gtpase activityGO:004308720.019
regulation of gtp catabolic processGO:003312420.019
cellular response to stressGO:0033554620.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of carbohydrate metabolic processGO:000610940.019
rho protein signal transductionGO:000726650.018
single organism organelle organizationGO:19025891990.018
regulation of nucleoside metabolic processGO:000911820.018
cellular ketone metabolic processGO:0042180110.018
cellular response to lipopolysaccharideGO:007122230.018
regulation of axonogenesisGO:0050770320.018
protein importGO:001703830.018
immune responseGO:0006955280.018
cellular component biogenesisGO:00440851780.018
organelle organizationGO:00069962270.018
myeloid leukocyte mediated immunityGO:000244410.018
regulation of nervous system developmentGO:0051960900.018
cell migration involved in gastrulationGO:0042074790.018
regulation of cell adhesionGO:0030155150.018
exocytosisGO:000688710.018
regulation of tube sizeGO:003515020.018
hormone secretionGO:004687920.018
leukocyte migrationGO:0050900150.018
actin filament based movementGO:003004810.018
regulation of anatomical structure morphogenesisGO:00226031300.018
regulation of circadian sleep wake cycleGO:004274910.018
positive regulation of transportGO:005105020.018
retina morphogenesis in camera type eyeGO:0060042790.018
synaptic vesicle localizationGO:009747910.018
cellular protein metabolic processGO:00442671290.018
leukocyte proliferationGO:007066110.018
positive regulation of secretionGO:005104710.018
regulation of reactive oxygen species metabolic processGO:200037720.018
myofibril assemblyGO:0030239480.018
neurological system processGO:0050877620.018
behaviorGO:0007610740.018
macrophage chemotaxisGO:004824630.017
heart developmentGO:00075073130.017
cell part morphogenesisGO:00329902460.017
positive regulation of cytoskeleton organizationGO:005149530.017
nucleocytoplasmic transportGO:000691340.017
leukocyte homeostasisGO:000177620.017
autophagyGO:000691440.017
cell projection organizationGO:00300302840.017
regulation of cell differentiationGO:00455951420.017
positive regulation of signalingGO:0023056560.017
regulation of erk1 and erk2 cascadeGO:007037240.017
gliogenesisGO:0042063450.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
organelle assemblyGO:00709251100.017
negative regulation of mapk cascadeGO:004340940.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
positive regulation of nucleotide catabolic processGO:003081310.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
regulation of programmed cell deathGO:00430671010.017
melanin metabolic processGO:000658220.017
cytoplasm organizationGO:000702840.017
regulation of neurotransmitter secretionGO:004692810.017
chemosensory behaviorGO:000763510.017
positive regulation of protein polymerizationGO:003227320.017
cell deathGO:00082191210.016
negative regulation of catabolic processGO:000989530.016
negative regulation of apoptotic processGO:0043066550.016
regulation of response to stressGO:0080134360.016
neutrophil homeostasisGO:000178010.016
neuron projection extensionGO:1990138450.016
lymphocyte proliferationGO:004665110.016
sleepGO:003043110.016
homeostatic processGO:00425921420.016
carbohydrate biosynthetic processGO:001605110.016
oxidation reduction processGO:0055114410.016
positive regulation of signal transductionGO:0009967560.016
nuclear transportGO:005116940.016
ion transportGO:00068111140.016
cellular response to molecule of bacterial originGO:007121930.016
regulation of protein transportGO:005122330.016
regulation of dendrite morphogenesisGO:004881430.016
protein secretionGO:000930610.016
camera type eye developmentGO:00430102220.016
startle responseGO:000196440.016
secondary metabolic processGO:001974830.016
regulation of neurogenesisGO:0050767870.016
negative regulation of nitrogen compound metabolic processGO:0051172590.016
skeletal muscle organ developmentGO:0060538780.016
cell growthGO:0016049570.016
modification dependent protein catabolic processGO:001994130.016
regulation of molecular functionGO:0065009700.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
cellular localizationGO:0051641970.015
defense response to fungusGO:005083220.015
protein acetylationGO:000647320.015
negative regulation of protein kinase b signalingGO:005189820.015
endosomal transportGO:001619720.015
neural crest cell differentiationGO:0014033720.015
regulation of blood vessel sizeGO:005088020.015
cell chemotaxisGO:0060326170.015
deathGO:00162651210.015
intracellular signal transductionGO:0035556850.015
circadian sleep wake cycle processGO:002241020.015
negative regulation of chromosome organizationGO:200125110.015
bone remodelingGO:004684920.015
negative regulation of synapse assemblyGO:005196420.015
neurotransmitter secretionGO:000726920.015
circadian sleep wake cycleGO:004274520.015
hepaticobiliary system developmentGO:0061008980.015
establishment or maintenance of cell polarityGO:0007163290.015
glial cell migrationGO:000834730.015
organic cyclic compound metabolic processGO:19013603010.015
protein depolymerizationGO:005126110.015
macromolecule localizationGO:0033036540.015
developmental growthGO:00485891660.014
cellular protein modification processGO:00064641000.014
internal protein amino acid acetylationGO:000647520.014
response to nutrientGO:000758430.014
synaptic transmission cholinergicGO:000727140.014
heterocycle biosynthetic processGO:00181302150.014
cellular amine metabolic processGO:004410620.014
ubiquitin dependent protein catabolic processGO:000651130.014
transmembrane transportGO:00550851200.014
internal peptidyl lysine acetylationGO:001839320.014
peripheral nervous system developmentGO:0007422550.014
mesenchymal cell developmentGO:0014031780.014
protein targeting to nucleusGO:004474430.014
response to oxygen containing compoundGO:1901700550.014
Rat
negative regulation of multicellular organismal processGO:0051241690.014
inorganic ion transmembrane transportGO:0098660570.014
regulation of neutrophil extravasationGO:200038910.014
cellular response to biotic stimulusGO:007121630.014
spermatid differentiationGO:004851520.014
developmental growth involved in morphogenesisGO:0060560860.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
positive regulation of leukocyte chemotaxisGO:000269010.014
determination of left right symmetryGO:00073681790.014
regulation of protein localization to plasma membraneGO:190307610.014
phosphorylationGO:0016310690.014
positive regulation of response to woundingGO:190303650.014
regulation of protein kinase b signalingGO:005189680.014
negative regulation of signal transductionGO:0009968940.014
negative regulation of defense responseGO:003134820.014
organic acid metabolic processGO:0006082310.014
Rat
sensory organ developmentGO:00074233930.014
retinal ganglion cell axon guidanceGO:0031290350.014
ribonucleotide metabolic processGO:0009259270.014
regulation of cell deathGO:00109411030.014
blood vessel developmentGO:00015682460.014
anatomical structure homeostasisGO:0060249360.014
positive regulation of biosynthetic processGO:0009891680.014
lateral inhibitionGO:004633110.014
single organismal cell cell adhesionGO:0016337290.014
positive regulation of cellular metabolic processGO:0031325940.014
positive regulation of stress activated mapk cascadeGO:003287430.014
immune effector processGO:0002252230.014
lymphangiogenesisGO:0001946250.014
specification of symmetryGO:00097992040.014
neuron projection morphogenesisGO:00488121610.014
microtubule based processGO:0007017600.013
regulation of intracellular signal transductionGO:1902531570.013
meiotic cell cycle processGO:190304630.013
negative regulation of kinase activityGO:003367340.013
negative regulation of leukocyte differentiationGO:190210610.013
signal transduction by phosphorylationGO:0023014180.013
fatty acid transportGO:001590810.013
mapk cascadeGO:0000165180.013
organic cyclic compound biosynthetic processGO:19013622230.013
lipid catabolic processGO:001604240.013
cellular protein complex disassemblyGO:004362410.013
regulation of bindingGO:005109830.013
monoamine transportGO:001584410.013
response to drugGO:004249330.013
negative regulation of map kinase activityGO:004340720.013
regulation of establishment of protein localization to plasma membraneGO:009000310.013
protein localization to nucleusGO:003450430.013
response to lipidGO:0033993600.013
regenerationGO:0031099910.013
sensory perception of painGO:001923310.013
positive regulation of cellular biosynthetic processGO:0031328680.013
neuron projection guidanceGO:0097485860.013
sequestering of calcium ionGO:005120830.012
protein acylationGO:004354330.012
regulation of phosphate metabolic processGO:0019220430.012
regulation of cell proliferationGO:0042127370.012
positive regulation of leukocyte differentiationGO:190210710.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
regulation of apoptotic processGO:0042981980.012
regulation of tissue remodelingGO:003410320.012
production of molecular mediator of immune responseGO:000244020.012
regulation of calcium ion transportGO:005192420.012
regulation of protein metabolic processGO:0051246560.012
actin filament based processGO:0030029640.012
positive regulation of immune system processGO:0002684170.012
negative regulation of cytokine productionGO:000181810.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of protein complex disassemblyGO:004324410.012
positive regulation of cellular amine metabolic processGO:003324000.012
developmental maturationGO:0021700340.012
positive regulation of chronic inflammatory responseGO:000267810.012
epidermal cell fate specificationGO:000995740.012
erk1 and erk2 cascadeGO:007037140.012
sexual reproductionGO:0019953360.012
response to amphetamineGO:000197510.012
regulation of autophagyGO:001050630.012
head developmentGO:00603223030.012
anterior posterior pattern specificationGO:00099521520.012
negative regulation of histone modificationGO:003105710.012

lta4h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
disease of metabolismDOID:001466700.020
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017