Danio rerio

0 known processes

tpma

alpha-tropomyosin

(Aliases: wu:fb37a09,tm,fb37a09,TPM1)

tpma biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle cell developmentGO:00550011150.824
Zebrafish
muscle system processGO:0003012200.755
Zebrafish Mouse
striated muscle cell developmentGO:00550021080.727
Zebrafish
larval developmentGO:000216420.715
Worm
sequestering of calcium ionGO:005120830.636
skeletal muscle thin filament assemblyGO:003024040.631
myofibril assemblyGO:0030239480.605
Zebrafish
skeletal myofibril assemblyGO:001486670.586
cardiac muscle cell differentiationGO:0055007300.543
Zebrafish
heart developmentGO:00075073130.491
Zebrafish Mouse Fly
purine nucleoside monophosphate catabolic processGO:000912840.480
striated muscle cell differentiationGO:00511461290.479
Zebrafish
ventricular cardiac myofibril assemblyGO:005500540.406
lymphoid lineage cell migrationGO:009753440.405
muscle cell differentiationGO:00426921390.392
Zebrafish
heart morphogenesisGO:00030071560.382
Mouse
reactive nitrogen species metabolic processGO:200105700.377
cellular component morphogenesisGO:00329893360.349
Zebrafish Fly
lymphoid lineage cell migration into thymusGO:009753540.291
cytokinesisGO:000091030.265
Worm
ventricular cardiac muscle tissue morphogenesisGO:005501020.255
Mouse
biosynthetic processGO:00090582940.252
cellular amino acid biosynthetic processGO:000865220.212
cellular biosynthetic processGO:00442492860.207
mitochondrion organizationGO:000700540.204
regulation of muscle contractionGO:000693730.201
maintenance of locationGO:005123540.192
skeletal muscle contractionGO:000300950.181
cardiac myofibril assemblyGO:005500390.169
Zebrafish
actomyosin structure organizationGO:0031032530.164
Zebrafish
cardiac muscle tissue developmentGO:0048738480.161
Zebrafish Mouse
musculoskeletal movementGO:005088180.157
actin filament based movementGO:003004810.155
ribonucleoside monophosphate catabolic processGO:000915840.150
cell matrix adhesionGO:000716040.148
lipid storageGO:001991510.145
sequestering of metal ionGO:005123830.139
ion transmembrane transportGO:0034220910.134
circadian sleep wake cycle sleepGO:005080210.131
nucleocytoplasmic transportGO:000691340.129
actin filament based processGO:0030029640.128
Zebrafish Worm
small molecule metabolic processGO:0044281770.127
regulation of biological qualityGO:00650082630.122
Mouse Worm
protein localization to nucleusGO:003450430.121
voluntary skeletal muscle contractionGO:000301040.113
regulation of nitric oxide mediated signal transductionGO:001074910.111
atp catabolic processGO:000620040.106
endocardial cushion formationGO:000327220.100
purine nucleotide metabolic processGO:0006163270.094
cellular modified amino acid metabolic processGO:000657530.093
nitrogen compound metabolic processGO:00068073190.093
positive regulation of biological processGO:00485182530.093
Mouse
twitch skeletal muscle contractionGO:001472140.092
single organism organelle organizationGO:19025891990.091
Zebrafish Worm
sarcomere organizationGO:0045214260.090
nitric oxide biosynthetic processGO:000680920.088
regulation of nucleoside metabolic processGO:000911820.087
regulation of synaptic plasticityGO:004816710.087
transmembrane transportGO:00550851200.086
regulation of sarcomere organizationGO:006029720.083
regulation of sequestering of calcium ionGO:005128240.080
nucleoside monophosphate catabolic processGO:000912540.078
organic substance biosynthetic processGO:19015762890.077
system processGO:00030081850.074
Zebrafish Mouse
neuron developmentGO:00486662620.073
Fly
blood vessel developmentGO:00015682460.072
muscle contractionGO:0006936180.072
Zebrafish Mouse
reactive oxygen species biosynthetic processGO:190340910.072
negative regulation of protein phosphorylationGO:000193340.070
cell morphogenesis involved in neuron differentiationGO:00486671630.070
Fly
somatic muscle developmentGO:000752540.069
response to biotic stimulusGO:0009607970.066
oxoacid metabolic processGO:0043436310.064
reactive oxygen species metabolic processGO:007259360.063
regulation of establishment of protein localizationGO:007020140.062
regulation of system processGO:0044057400.061
Mouse
cellular aromatic compound metabolic processGO:00067252950.060
venous blood vessel morphogenesisGO:004884530.057
cytoplasm organizationGO:000702840.057
Fly
neuron differentiationGO:00301823530.057
Fly
cellular component movementGO:00069283350.056
blood circulationGO:0008015870.056
Zebrafish Mouse
positive regulation of transportGO:005105020.056
negative regulation of sequestering of calcium ionGO:005128340.056
chemical homeostasisGO:0048878490.055
tube morphogenesisGO:00352393490.055
regulation of blood circulationGO:1903522320.054
Mouse
pole plasm assemblyGO:000731540.052
Fly
nitric oxide metabolic processGO:004620920.052
embryonic heart tube developmentGO:00350501330.051
establishment of localizationGO:00512342440.049
endoplasmic reticulum unfolded protein responseGO:003096820.049
growth plate cartilage morphogenesisGO:000342210.049
cell substrate adhesionGO:003158940.049
regulation of nucleobase containing compound metabolic processGO:00192192500.048
anatomical structure homeostasisGO:0060249360.048
ribonucleotide metabolic processGO:0009259270.047
carboxylic acid metabolic processGO:0019752220.047
purine ribonucleotide metabolic processGO:0009150270.046
regulation of jak stat cascadeGO:004642530.046
multicellular organismal movementGO:005087980.046
ion transportGO:00068111140.045
maternal determination of anterior posterior axis embryoGO:000835840.045
Fly
regulation of macromolecule biosynthetic processGO:00105562250.045
muscle structure developmentGO:00610611960.044
Zebrafish Mouse
striated muscle tissue developmentGO:00147061100.044
Zebrafish Mouse
regulation of protein bindingGO:004339330.044
Worm
cardiac muscle tissue morphogenesisGO:005500870.044
Mouse
organelle assemblyGO:00709251100.043
Zebrafish
post embryonic organ developmentGO:004856940.043
regulation of signalingGO:00230512350.043
nucleobase containing compound metabolic processGO:00061392740.042
regulation of cell projection assemblyGO:006049140.042
Fly
single organism biosynthetic processGO:0044711710.042
response to external stimulusGO:00096052640.042
positive regulation of nitrogen compound metabolic processGO:0051173690.042
cell projection morphogenesisGO:00488582440.041
Fly
behaviorGO:0007610740.040
Worm
regulation of purine nucleotide catabolic processGO:003312120.040
nitric oxide mediated signal transductionGO:000726320.040
regulation of localizationGO:00328791040.040
rna localizationGO:000640340.039
Fly
cardiac muscle fiber developmentGO:004873930.039
response to organic substanceGO:00100331530.038
regulation of ion transmembrane transporter activityGO:003241220.037
response to oxidative stressGO:0006979110.037
regulation of nucleotide catabolic processGO:003081120.036
heart processGO:0003015710.035
Zebrafish Mouse
striated muscle contractionGO:0006941120.035
Zebrafish Mouse
generation of neuronsGO:00486993850.035
Fly
anterior posterior pattern specificationGO:00099521520.035
Fly
cellular component assemblyGO:00226071700.034
Zebrafish Worm Fly
cardiac muscle cell developmentGO:0055013200.034
Zebrafish
somitogenesisGO:0001756870.034
endocardial cushion morphogenesisGO:000320330.034
ventricular cardiac muscle cell differentiationGO:005501260.034
cellular component maintenanceGO:004395430.034
regulation of cell shapeGO:000836010.033
pigmentationGO:0043473850.033
regulation of heart contractionGO:0008016320.033
Mouse
regulation of intracellular protein transportGO:003315730.033
organic acid metabolic processGO:0006082310.033
adult behaviorGO:003053420.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
small molecule catabolic processGO:004428230.032
purine containing compound metabolic processGO:0072521290.031
muscle organ developmentGO:00075171010.031
Mouse
purine ribonucleoside monophosphate catabolic processGO:000916940.031
nucleobase containing small molecule metabolic processGO:0055086320.031
regulation of cellular metabolic processGO:00313233200.031
cellular metal ion homeostasisGO:0006875160.031
metal ion homeostasisGO:0055065260.030
mesenchyme developmentGO:00604851270.030
transportGO:00068102200.030
heterocycle biosynthetic processGO:00181302150.030
locomotionGO:00400113130.029
Worm
hematopoietic stem cell differentiationGO:0060218200.029
regulation of metal ion transportGO:001095940.029
single organism transportGO:00447652060.029
axon developmentGO:00615641660.029
single organism metabolic processGO:00447102170.028
ribose phosphate metabolic processGO:0019693270.028
regulation of response to stimulusGO:00485832690.028
cellular calcium ion homeostasisGO:0006874130.028
cell motilityGO:00488702440.027
protein importGO:001703830.027
cellular nitrogen compound metabolic processGO:00346412900.027
cardiocyte differentiationGO:0035051440.027
Zebrafish
organonitrogen compound metabolic processGO:1901564740.027
organelle organizationGO:00069962270.027
Zebrafish Worm
regulation of cell communicationGO:00106462320.026
regulation of protein targetingGO:190353320.026
muscle tissue developmentGO:00605371100.026
Zebrafish Mouse
regulation of circadian sleep wake cycle sleepGO:004518710.026
cell morphogenesisGO:00009022890.025
Fly
regulation of nitrogen compound metabolic processGO:00511712510.025
organic cyclic compound biosynthetic processGO:19013622230.025
cell morphogenesis involved in differentiationGO:00009041950.025
Fly
circadian sleep wake cycleGO:004274520.025
microtubule organizing center organizationGO:003102310.025
nucleotide metabolic processGO:0009117280.025
oogenesisGO:0048477140.024
Fly
somite developmentGO:0061053960.024
negative regulation of cellular processGO:00485232830.024
Worm
regulation of circadian rhythmGO:004275240.024
multi organism processGO:00517041340.024
Worm Fly
intracellular signal transductionGO:0035556850.024
axonogenesisGO:00074091520.023
endocardial cushion developmentGO:000319760.023
neuron projection developmentGO:00311751800.023
Fly
positive regulation of rna metabolic processGO:0051254590.023
regulation of cell substrate adhesionGO:001081010.023
carbohydrate homeostasisGO:003350010.023
regulation of nucleocytoplasmic transportGO:004682220.023
protein import into nucleusGO:000660630.023
phosphate containing compound metabolic processGO:00067961080.023
angiogenesisGO:00015251580.023
homeostatic processGO:00425921420.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
membrane repolarizationGO:008600920.022
ion homeostasisGO:0050801410.022
positive regulation of muscle cell differentiationGO:005114910.022
cellular response to organic substanceGO:00713101050.022
skeletal muscle organ developmentGO:0060538780.022
carbohydrate derivative metabolic processGO:1901135610.021
calcium ion homeostasisGO:0055074190.021
cardiac ventricle developmentGO:000323190.021
Mouse
neurotransmitter transportGO:000683620.021
negative regulation of protein kinase activityGO:000646940.021
single organism nuclear importGO:190259330.021
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.021
glycosyl compound metabolic processGO:1901657110.021
regulation of multicellular organismal processGO:00512392770.020
Mouse
cellular protein catabolic processGO:004425740.020
regulation of signal transductionGO:00099662250.020
blood vessel morphogenesisGO:00485142160.020
negative regulation of biological processGO:00485193040.020
Worm
regulation of circadian sleep wake cycleGO:004274910.020
regulation of macromolecule metabolic processGO:00602553170.020
response to stressGO:00069502630.020
cytoskeleton dependent cytokinesisGO:006164030.020
cardiac muscle contractionGO:006004860.020
Zebrafish Mouse
cellular ion homeostasisGO:0006873170.019
circadian sleep wake cycle processGO:002241020.019
response to organic cyclic compoundGO:0014070510.019
stem cell differentiationGO:00488631170.019
nuclear transportGO:005116940.019
response to activityGO:0014823140.019
cardiac ventricle morphogenesisGO:000320870.019
Mouse
morphogenesis of an epitheliumGO:00020093330.019
slow twitch skeletal muscle fiber contractionGO:003144430.019
segmentationGO:0035282970.019
Fly
positive regulation of gene expressionGO:0010628710.019
negative regulation of epithelial cell proliferationGO:005068010.019
regulation of cellular amine metabolic processGO:003323800.018
divalent inorganic cation homeostasisGO:0072507220.018
response to chemicalGO:00422213200.018
establishment of protein localization to organelleGO:007259440.018
immune system developmentGO:00025201910.018
oocyte developmentGO:0048599140.018
Fly
positive regulation of cellular catabolic processGO:003133130.018
regionalizationGO:00030022740.018
Fly
carboxylic acid biosynthetic processGO:0046394120.018
regulation of transmembrane transporter activityGO:002289820.017
nucleic acid metabolic processGO:00903042440.017
release of sequestered calcium ion into cytosolGO:005120930.017
heterocycle metabolic processGO:00464832900.017
positive regulation of blood circulationGO:190352420.017
Mouse
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.017
cell projection organizationGO:00300302840.017
Fly
synaptic growth at neuromuscular junctionGO:005112420.017
regulation of epithelial to mesenchymal transitionGO:001071730.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of protein complex assemblyGO:004325430.017
Worm
connective tissue developmentGO:0061448990.016
single organism localizationGO:19025782250.016
Fly
oocyte anterior posterior axis specificationGO:000731440.016
Fly
agingGO:000756820.016
cell migrationGO:00164772370.016
regulation of transmembrane transportGO:0034762180.016
regulation of homeostatic processGO:003284490.016
regulation of blood pressureGO:000821710.016
Mouse
localization of cellGO:00516742440.016
determination of bilateral symmetryGO:00098552040.016
immune system processGO:00023762410.016
cellular amino acid metabolic processGO:000652070.016
organophosphate metabolic processGO:0019637370.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
cell death in response to oxidative stressGO:003647320.016
embryonic organ developmentGO:00485683810.016
neuromuscular synaptic transmissionGO:000727420.016
heart loopingGO:0001947940.016
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of protein polymerizationGO:003227120.015
Worm
hemopoiesisGO:00300971830.015
regulation of jun kinase activityGO:004350630.015
cellular aldehyde metabolic processGO:000608140.015
purine ribonucleoside monophosphate metabolic processGO:000916750.015
proteasomal protein catabolic processGO:001049820.015
positive regulation of rna biosynthetic processGO:1902680570.015
regulation of rna biosynthetic processGO:20011412130.015
cellular localizationGO:0051641970.015
Fly
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.015
taxisGO:00423301090.014
ribonucleoside monophosphate metabolic processGO:000916150.014
protein stabilizationGO:005082120.014
nuclear importGO:005117030.014
single organism behaviorGO:0044708240.014
heart contractionGO:0060047710.014
Zebrafish Mouse
ventricular cardiac muscle tissue developmentGO:000322930.014
Mouse
cellular response to endogenous stimulusGO:0071495680.014
chordate embryonic developmentGO:00430092710.014
Mouse
epithelial tube morphogenesisGO:00605621480.014
muscle tissue morphogenesisGO:006041570.014
Mouse
positive regulation of striated muscle cell differentiationGO:005115510.014
response to corticosteroidGO:003196010.014
programmed cell deathGO:00125011190.014
developmental maturationGO:0021700340.014
Fly
regulation of ion transportGO:0043269220.014
cellular response to external stimulusGO:007149620.014
muscle fiber developmentGO:0048747520.013
cellular response to abiotic stimulusGO:007121440.013
amine metabolic processGO:000930820.013
neuron projection morphogenesisGO:00488121610.013
Fly
small molecule biosynthetic processGO:0044283160.013
regulation of cell matrix adhesionGO:000195210.013
protein metabolic processGO:00195381830.013
response to other organismGO:0051707970.013
positive regulation of cellular biosynthetic processGO:0031328680.013
multi organism reproductive processGO:0044703360.013
Worm Fly
determination of left right symmetryGO:00073681790.013
monocarboxylic acid metabolic processGO:0032787170.013
cellular component biogenesisGO:00440851780.012
Zebrafish Worm Fly
response to drugGO:004249330.012
regulation of calcium ion transportGO:005192420.012
single organism cellular localizationGO:1902580460.012
Fly
ribonucleoside metabolic processGO:0009119110.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
lipid catabolic processGO:001604240.012
phosphorus metabolic processGO:00067931090.012
aromatic compound biosynthetic processGO:00194382170.012
signal transductionGO:00071654550.012
multicellular organismal response to stressGO:003355520.012
protein acylationGO:004354330.012
pronephros developmentGO:0048793690.012
single organism intracellular transportGO:1902582250.012
mitotic cytokinesisGO:000028130.012
embryonic heart tube morphogenesisGO:00031431080.012
regulation of cytoplasmic transportGO:190364940.012
mitotic cell cycleGO:0000278640.012
regulation of cellular amino acid metabolic processGO:000652100.011
cellular response to stressGO:0033554620.011
cardiac chamber developmentGO:0003205190.011
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of cellular ketone metabolic processGO:001056570.011
response to glucocorticoidGO:005138410.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
regulation of protein import into nucleusGO:004230620.011
cellular cation homeostasisGO:0030003170.011
rna biosynthetic processGO:00327741810.011
cell junction maintenanceGO:003433120.011
response to steroid hormoneGO:0048545350.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
regulation of protein transportGO:005122330.011
cell cycle arrestGO:000705010.011
specification of axis polarityGO:006500140.011
cellular homeostasisGO:0019725260.011
regulation of protein localization to nucleusGO:190018020.011
adherens junction maintenanceGO:003433420.011
protein targeting to nucleusGO:004474430.011
regulation of muscle system processGO:009025750.010
regulation of transportGO:0051049450.010
cellular divalent inorganic cation homeostasisGO:0072503130.010
regulation of cellular biosynthetic processGO:00313262450.010
negative regulation of kinase activityGO:003367340.010
cell deathGO:00082191210.010
cell cycle processGO:0022402530.010
Worm
regulation of cardiac muscle contractionGO:005511720.010
regulation of metabolic processGO:00192223590.010
cellular response to radiationGO:007147840.010
cytoskeleton organizationGO:0007010960.010
Zebrafish Worm
digestive system developmentGO:00551232890.010
Worm
cell cell signalingGO:0007267520.010

tpma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.054
musculoskeletal system diseaseDOID:1700.031
muscular diseaseDOID:008000000.014
nervous system diseaseDOID:86300.013
neuromuscular diseaseDOID:44000.013
charcot marie tooth diseaseDOID:1059500.013
neuropathyDOID:87000.013
muscle tissue diseaseDOID:6600.011
distal arthrogryposisDOID:005064600.011