Danio rerio

17 known processes

cdkl1

cyclin-dependent kinase-like 1 (CDC2-related kinase)

(Aliases: zgc:101002)

cdkl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823530.562
cell projection organizationGO:00300302840.514
locomotionGO:00400113130.469
cell motilityGO:00488702440.436
negative regulation of cellular processGO:00485232830.387
epithelial tube morphogenesisGO:00605621480.371
morphogenesis of an epitheliumGO:00020093330.347
generation of neuronsGO:00486993850.329
cellular component movementGO:00069283350.315
developmental growthGO:00485891660.304
hemopoiesisGO:00300971830.295
organonitrogen compound metabolic processGO:1901564740.288
embryonic organ morphogenesisGO:00485622740.285
neuron projection developmentGO:00311751800.282
determination of heart left right asymmetryGO:00613711170.268
cell morphogenesis involved in differentiationGO:00009041950.256
rna metabolic processGO:00160702190.245
signal transductionGO:00071654550.230
cellular macromolecule metabolic processGO:00442603910.228
cellular aromatic compound metabolic processGO:00067252950.220
heterocycle biosynthetic processGO:00181302150.211
growthGO:00400071740.205
organic substance biosynthetic processGO:19015762890.200
regulation of cell deathGO:00109411030.192
cell migrationGO:00164772370.188
cellular component morphogenesisGO:00329893360.187
axon guidanceGO:0007411860.186
head developmentGO:00603223030.185
sensory organ developmentGO:00074233930.184
sensory organ morphogenesisGO:00905962000.176
cell surface receptor signaling pathwayGO:00071663250.173
determination of bilateral symmetryGO:00098552040.173
guanosine containing compound metabolic processGO:190106840.172
urogenital system developmentGO:0001655970.172
protein metabolic processGO:00195381830.167
neuron developmentGO:00486662620.167
chordate embryonic developmentGO:00430092710.163
determination of left right symmetryGO:00073681790.159
multicellular organismal homeostasisGO:0048871290.152
cell part morphogenesisGO:00329902460.148
regulation of cellular metabolic processGO:00313233200.147
cellular component assemblyGO:00226071700.147
heterocycle metabolic processGO:00464832900.143
digestive tract developmentGO:00485652650.141
small gtpase mediated signal transductionGO:000726480.140
biosynthetic processGO:00090582940.139
single organism biosynthetic processGO:0044711710.138
heart loopingGO:0001947940.137
synaptic growth at neuromuscular junctionGO:005112420.136
tube morphogenesisGO:00352393490.135
organic cyclic compound metabolic processGO:19013603010.135
regulation of rna biosynthetic processGO:20011412130.134
larval developmentGO:000216420.134
gene expressionGO:00104672520.133
regulation of cell differentiationGO:00455951420.133
positive regulation of biological processGO:00485182530.131
central nervous system developmentGO:00074173870.130
central nervous system neuron differentiationGO:0021953740.129
agingGO:000756820.128
cellular nitrogen compound biosynthetic processGO:00442712180.126
regulation of cell communicationGO:00106462320.125
small molecule metabolic processGO:0044281770.120
nucleic acid templated transcriptionGO:00976591810.117
stem cell differentiationGO:00488631170.116
regulation of cellular biosynthetic processGO:00313262450.115
cellular biosynthetic processGO:00442492860.113
cellular nitrogen compound metabolic processGO:00346412900.110
gtp metabolic processGO:004603940.110
organic cyclic compound biosynthetic processGO:19013622230.110
cell morphogenesis involved in neuron differentiationGO:00486671630.110
axonogenesisGO:00074091520.105
guanosine containing compound catabolic processGO:190106920.102
positive regulation of cellular component biogenesisGO:004408930.101
axon developmentGO:00615641660.099
regulation of primary metabolic processGO:00800903110.096
regulation of synapse organizationGO:005080730.095
response to chemicalGO:00422213200.095
localization of cellGO:00516742440.093
regulation of nitrogen compound metabolic processGO:00511712510.092
carbohydrate derivative metabolic processGO:1901135610.091
aromatic compound biosynthetic processGO:00194382170.091
oxoacid metabolic processGO:0043436310.086
nucleoside phosphate metabolic processGO:0006753280.084
regulation of embryonic developmentGO:0045995470.084
amine metabolic processGO:000930820.083
negative regulation of cell communicationGO:0010648960.083
regulation of biological qualityGO:00650082630.083
rna biosynthetic processGO:00327741810.082
cell projection morphogenesisGO:00488582440.081
digestive tract morphogenesisGO:00485462310.081
gtp catabolic processGO:000618420.076
muscle structure developmentGO:00610611960.075
regulation of cell morphogenesis involved in differentiationGO:0010769380.072
neuron projection guidanceGO:0097485860.069
hematopoietic or lymphoid organ developmentGO:00485341910.069
regulation of cellular amino acid metabolic processGO:000652100.069
response to stressGO:00069502630.069
regulation of cellular macromolecule biosynthetic processGO:20001122220.069
organelle organizationGO:00069962270.069
system processGO:00030081850.069
chemotaxisGO:00069351040.068
negative regulation of signalingGO:0023057960.068
stem cell maintenanceGO:001982740.064
deathGO:00162651210.063
specification of symmetryGO:00097992040.063
intracellular signal transductionGO:0035556850.062
nucleobase containing compound biosynthetic processGO:00346542050.062
transcription dna templatedGO:00063511810.062
convergent extensionGO:00600261180.062
primary neural tube formationGO:001402010.061
establishment of localizationGO:00512342440.061
neuron projection morphogenesisGO:00488121610.060
multicellular organism growthGO:003526440.060
inorganic cation transmembrane transportGO:0098662500.059
cellular amino acid metabolic processGO:000652070.058
regulation of multicellular organism growthGO:004001440.058
phosphorus metabolic processGO:00067931090.057
positive regulation of cellular processGO:00485222010.057
positive regulation of metabolic processGO:00098931080.057
inner ear developmentGO:00488391260.055
cellular response to chemical stimulusGO:00708871570.054
nucleobase containing compound metabolic processGO:00061392740.054
negative regulation of protein phosphorylationGO:000193340.053
macromolecule biosynthetic processGO:00090592270.052
cellular ketone metabolic processGO:0042180110.052
regulation of cell developmentGO:00602841000.052
cell morphogenesisGO:00009022890.052
embryo development ending in birth or egg hatchingGO:00097922710.051
taxisGO:00423301090.051
regulation of metabolic processGO:00192223590.051
immune system processGO:00023762410.051
response to external stimulusGO:00096052640.050
regionalizationGO:00030022740.049
epithelial cilium movementGO:0003351150.048
negative regulation of signal transductionGO:0009968940.047
tissue homeostasisGO:0001894250.047
regulation of synapse assemblyGO:005196330.046
regulation of signal transductionGO:00099662250.045
regulation of molecular functionGO:0065009700.045
regulation of cellular ketone metabolic processGO:001056570.045
brain developmentGO:00074202930.045
melanin metabolic processGO:000658220.044
organonitrogen compound biosynthetic processGO:1901566470.044
negative regulation of apoptotic processGO:0043066550.043
segmentationGO:0035282970.043
basement membrane organizationGO:007171150.042
cation transmembrane transportGO:0098655650.042
heart morphogenesisGO:00030071560.042
positive regulation of cell cycleGO:004578730.042
regulation of signalingGO:00230512350.041
regulation of gene expressionGO:00104682650.041
regulation of programmed cell deathGO:00430671010.040
neurotransmitter transportGO:000683620.039
inorganic ion transmembrane transportGO:0098660570.039
nucleic acid metabolic processGO:00903042440.039
cellular protein catabolic processGO:004425740.038
mesenchyme developmentGO:00604851270.038
negative regulation of biological processGO:00485193040.038
carbon dioxide transportGO:001567030.038
cellular component biogenesisGO:00440851780.037
negative regulation of response to stimulusGO:00485851040.037
transportGO:00068102200.037
embryonic skeletal system morphogenesisGO:0048704930.037
heart processGO:0003015710.037
nucleotide metabolic processGO:0009117280.037
purine containing compound metabolic processGO:0072521290.036
regulation of apoptotic processGO:0042981980.036
regulation of catalytic activityGO:0050790550.036
regulation of multicellular organismal processGO:00512392770.035
ear developmentGO:00435831270.035
cell projection assemblyGO:0030031640.035
cellular response to external stimulusGO:007149620.035
regulation of gtp catabolic processGO:003312420.034
regulation of cellular component organizationGO:0051128860.034
cortical actin cytoskeleton organizationGO:003086610.034
blood circulationGO:0008015870.033
regulation of rna metabolic processGO:00512522240.033
embryonic skeletal joint developmentGO:007249830.033
glial cell developmentGO:0021782200.033
positive regulation of cellular catabolic processGO:003133130.032
water homeostasisGO:003010440.032
ribose phosphate metabolic processGO:0019693270.032
macromolecular complex subunit organizationGO:0043933740.032
regulation of transcription dna templatedGO:00063552130.031
regulation of heart growthGO:006042020.031
regulation of phosphorus metabolic processGO:0051174430.031
ion transmembrane transportGO:0034220910.031
response to woundingGO:00096111160.031
response to organic substanceGO:00100331530.029
regulation of microtubule based movementGO:006063230.029
cation transportGO:0006812810.029
embryonic viscerocranium morphogenesisGO:0048703520.029
cellular protein modification processGO:00064641000.029
digestive system developmentGO:00551232890.029
circulatory system processGO:0003013870.029
cell substrate junction assemblyGO:000704420.028
single organism transportGO:00447652060.028
cytokinesisGO:000091030.027
rhombomere 4 developmentGO:002157050.027
rho protein signal transductionGO:000726650.027
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
anterior posterior pattern specificationGO:00099521520.027
morphogenesis of an epithelial foldGO:006057110.027
cell proliferationGO:0008283800.027
organic acid metabolic processGO:0006082310.027
immune system developmentGO:00025201910.027
single organism organelle organizationGO:19025891990.027
protein importGO:001703830.027
nucleobase containing small molecule metabolic processGO:0055086320.027
cellular response to organic substanceGO:00713101050.027
regulation of purine nucleotide catabolic processGO:003312120.026
cell deathGO:00082191210.026
nitrogen compound metabolic processGO:00068073190.026
cell substrate adherens junction assemblyGO:000704510.026
macromolecule modificationGO:00434121110.026
establishment or maintenance of cell polarityGO:0007163290.026
single organism metabolic processGO:00447102170.025
regulation of cell shapeGO:000836010.025
cellular component assembly involved in morphogenesisGO:00109271070.025
nephron tubule morphogenesisGO:007207810.025
monovalent inorganic cation transportGO:0015672420.024
synapse assemblyGO:000741690.024
neuromuscular junction developmentGO:000752890.024
embryonic heart tube developmentGO:00350501330.024
cell agingGO:000756920.024
erythrocyte differentiationGO:0030218540.024
cellular localizationGO:0051641970.024
positive regulation of transportGO:005105020.024
startle responseGO:000196440.023
retina morphogenesis in camera type eyeGO:0060042790.023
regulation of nucleoside metabolic processGO:000911820.023
regulation of protein metabolic processGO:0051246560.023
forebrain anterior posterior pattern specificationGO:002179730.023
myeloid cell homeostasisGO:0002262560.023
heart contractionGO:0060047710.022
modification dependent macromolecule catabolic processGO:004363230.022
regulation of growthGO:0040008420.022
regulation of cellular amine metabolic processGO:003323800.022
cellular macromolecule biosynthetic processGO:00346452240.022
negative regulation of cell deathGO:0060548600.022
regulation of reproductive processGO:200024140.022
female sex differentiationGO:004666040.022
action potentialGO:0001508190.022
androgen biosynthetic processGO:000670210.022
regulation of cell morphogenesisGO:0022604420.022
multi organism processGO:00517041340.022
regulation of anatomical structure morphogenesisGO:00226031300.022
regulation of phosphate metabolic processGO:0019220430.022
leukocyte proliferationGO:007066110.021
regulation of nucleotide catabolic processGO:003081120.021
regulation of nuclear divisionGO:005178390.021
embryonic cranial skeleton morphogenesisGO:0048701900.021
spinal cord developmentGO:0021510460.021
neural tube developmentGO:0021915620.021
establishment of organelle localizationGO:0051656450.021
embryonic limb morphogenesisGO:003032620.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
stem cell proliferationGO:007208940.021
negative regulation of response to cytokine stimulusGO:006076120.020
gastrulationGO:00073692080.020
segment polarity determinationGO:000736710.020
gland developmentGO:00487321430.020
single organism localizationGO:19025782250.020
regulation of organelle organizationGO:0033043290.020
purine nucleotide metabolic processGO:0006163270.020
positive regulation of multicellular organismal processGO:0051240520.020
cortical cytoskeleton organizationGO:003086510.020
embryonic organ developmentGO:00485683810.019
negative regulation of muscle tissue developmentGO:190186220.019
regulation of blood circulationGO:1903522320.019
multicellular organismal signalingGO:0035637220.019
hepatic duct developmentGO:006101120.019
regulation of response to stimulusGO:00485832690.019
regulation of macromolecule metabolic processGO:00602553170.019
actin cytoskeleton organizationGO:0030036630.019
regulation of nervous system developmentGO:0051960900.019
embryonic digestive tract morphogenesisGO:004855730.019
thrombocyte differentiationGO:000257440.019
regulation of dendrite developmentGO:005077330.019
regulation of rho protein signal transductionGO:003502320.019
positive regulation of epithelial cell differentiationGO:003085820.019
notochord developmentGO:0030903540.018
positive regulation of gliogenesisGO:001401520.018
anion homeostasisGO:005508190.018
cellular biogenic amine metabolic processGO:000657620.018
positive regulation of macromolecule metabolic processGO:0010604930.018
regulation of cellular protein metabolic processGO:0032268520.018
stem cell developmentGO:0048864820.018
neural crest cell migrationGO:0001755420.018
g1 s transition of mitotic cell cycleGO:000008210.018
neurological system processGO:0050877620.018
organophosphate metabolic processGO:0019637370.018
mediolateral intercalationGO:006003130.018
homeostatic processGO:00425921420.018
apoptotic processGO:00069151160.018
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.018
regulation of establishment of protein localizationGO:007020140.018
protein heterooligomerizationGO:005129110.018
regulation of cell projection organizationGO:0031344440.018
striated muscle cell developmentGO:00550021080.017
positive regulation of cell differentiationGO:0045597300.017
cell growthGO:0016049570.017
cytoskeleton organizationGO:0007010960.017
modification dependent protein catabolic processGO:001994130.017
actin filament based processGO:0030029640.017
muscle tissue developmentGO:00605371100.017
cellular amine metabolic processGO:004410620.017
mesenchymal cell developmentGO:0014031780.017
positive regulation of cellular metabolic processGO:0031325940.017
brain morphogenesisGO:0048854180.017
secondary metabolic processGO:001974830.017
regulation of cardiac muscle tissue developmentGO:005502410.016
regulation of gtpase activityGO:004308720.016
neuromuscular synaptic transmissionGO:000727420.016
epithelial cell proliferation involved in liver morphogenesisGO:007257520.016
germ line stem cell maintenanceGO:003071820.016
transcription from rna polymerase ii promoterGO:0006366800.016
organic substance catabolic processGO:1901575280.016
mesoderm developmentGO:0007498880.016
regulation of developmental processGO:00507932470.016
single organismal cell cell adhesionGO:0016337290.016
regulation of cell activationGO:005086510.016
response to nutrient levelsGO:0031667100.016
bmp signaling pathway involved in determination of left right symmetryGO:0003154140.016
negative regulation of gene expressionGO:0010629650.016
developmental growth involved in morphogenesisGO:0060560860.016
carboxylic acid metabolic processGO:0019752220.016
regulation of neurological system processGO:003164420.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of membrane potentialGO:0042391230.016
alpha amino acid metabolic processGO:190160530.016
muscle organ developmentGO:00075171010.015
regulation of cytokine biosynthetic processGO:004203510.015
oocyte maturationGO:000155640.015
cellular response to endogenous stimulusGO:0071495680.015
gall bladder developmentGO:006101010.015
glomerulus developmentGO:0032835270.015
nucleoside metabolic processGO:0009116110.015
convergent extension involved in gastrulationGO:0060027710.015
blood coagulation fibrin clot formationGO:007237830.015
regulation of protein catabolic processGO:004217610.015
mesenchymal cell differentiationGO:0048762870.015
positive regulation of carbohydrate metabolic processGO:004591310.015
organelle localizationGO:0051640490.015
g protein coupled receptor signaling pathwayGO:0007186740.015
single organism cellular localizationGO:1902580460.015
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.015
cellular response to fibroblast growth factor stimulusGO:0044344220.014
retina development in camera type eyeGO:00600411460.014
organelle assemblyGO:00709251100.014
transmission of nerve impulseGO:0019226190.014
hepatocyte proliferationGO:007257420.014
antimicrobial humoral responseGO:001973020.014
eye developmentGO:00016542770.014
cell cycle g1 s phase transitionGO:004484310.014
positive regulation of muscle organ developmentGO:004863610.014
single organism nuclear importGO:190259330.014
fin regenerationGO:0031101510.014
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.014
purine ribonucleotide metabolic processGO:0009150270.014
nuclear importGO:005117030.014
negative regulation of multicellular organismal processGO:0051241690.014
regulation of protein import into nucleusGO:004230620.014
negative regulation of rna metabolic processGO:0051253480.014
anterior head developmentGO:009706520.014
chondrocyte developmentGO:000206340.014
negative regulation of striated muscle tissue developmentGO:004584320.014
b cell activationGO:004211320.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
embryonic skeletal joint morphogenesisGO:006027230.013
peripheral nervous system neuron differentiationGO:0048934280.013
embryonic heart tube morphogenesisGO:00031431080.013
positive regulation of catabolic processGO:000989640.013
regulation of anterior head developmentGO:200074220.013
ribonucleotide metabolic processGO:0009259270.013
regulation of biosynthetic processGO:00098892500.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
nuclear transportGO:005116940.013
cellular nitrogen compound catabolic processGO:0044270150.013
kupffer s vesicle developmentGO:0070121500.013
regulation of oocyte developmentGO:006028130.013
multicellular organismal metabolic processGO:004423620.013
regulation of protein localization to nucleusGO:190018020.013
regulation of protein modification by small protein conjugation or removalGO:190332030.012
kidney developmentGO:0001822920.012
regulation of bindingGO:005109830.012
production of molecular mediator of immune responseGO:000244020.012
single organism reproductive processGO:0044702400.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.012
embryonic digestive tract developmentGO:004856640.012
cytoskeleton dependent cytokinesisGO:006164030.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
central nervous system projection neuron axonogenesisGO:0021952150.012
heart developmentGO:00075073130.012
Rat
regenerationGO:0031099910.012
regulation of protein transportGO:005122330.012
vesicle mediated transportGO:0016192220.012
nucleocytoplasmic transportGO:000691340.012
organic substance transportGO:0071702580.012
regulation of protein ubiquitinationGO:003139630.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
positive regulation of apoptotic processGO:0043065290.012
regulation of macromolecule biosynthetic processGO:00105562250.012
mononuclear cell proliferationGO:003294310.012
programmed cell deathGO:00125011190.012
regulation of protein complex assemblyGO:004325430.012
negative regulation of developmental processGO:0051093650.012
peptide transportGO:001583310.011
adult behaviorGO:003053420.011
glomerular basement membrane developmentGO:003283650.011
tube formationGO:0035148250.011
protein modification processGO:00362111000.011
central nervous system neuron developmentGO:0021954290.011
regulation of cellular component movementGO:0051270550.011
eye morphogenesisGO:00485921440.011
response to alkaloidGO:004327920.011
calcium ion homeostasisGO:0055074190.011
regulation of multicellular organismal developmentGO:20000262230.011
ear morphogenesisGO:0042471640.011
cardiac cell fate commitmentGO:006091110.011
negative regulation of mitosisGO:004583930.011
protein complex subunit organizationGO:0071822460.011
apoptotic signaling pathwayGO:0097190230.011
cell cycleGO:0007049930.011
meiotic nuclear divisionGO:000712640.011
regulation of cytoplasmic transportGO:190364940.011
protein import into nucleusGO:000660630.011
positive regulation of nucleotide catabolic processGO:003081310.011
mitotic nuclear divisionGO:0007067180.011
cell divisionGO:0051301200.011
negative regulation of rna biosynthetic processGO:1902679450.011
regulation of oligodendrocyte differentiationGO:004871310.011
positive regulation of cell developmentGO:0010720250.011
ion homeostasisGO:0050801410.011
protein complex biogenesisGO:0070271300.011
dendrite developmentGO:001635890.011
ventral spinal cord developmentGO:0021517350.011
embryonic skeletal system developmentGO:0048706970.010
muscle fiber developmentGO:0048747520.010
nephron epithelium morphogenesisGO:007208810.010
negative regulation of cell differentiationGO:0045596460.010
negative regulation of macromolecule biosynthetic processGO:0010558480.010
single organism cell adhesionGO:0098602290.010

cdkl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.083
connective tissue diseaseDOID:6500.029
musculoskeletal system diseaseDOID:1700.029
bone development diseaseDOID:008000600.029
bone diseaseDOID:008000100.029
osteochondrodysplasiaDOID:225600.023
nervous system diseaseDOID:86300.021
disease of cellular proliferationDOID:1456600.021
endocrine gland cancerDOID:17000.018
cancerDOID:16200.018
organ system cancerDOID:005068600.018
urinary system diseaseDOID:1800.016
urinary system cancerDOID:399600.014
heart diseaseDOID:11400.011
cardiovascular system diseaseDOID:128700.011