Danio rerio

0 known processes

soul4

heme-binding protein soul4

soul4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell surface receptor signaling pathwayGO:00071663250.196
regulation of biological qualityGO:00650082630.187
morphogenesis of an epitheliumGO:00020093330.184
regulation of multicellular organismal processGO:00512392770.153
single organism localizationGO:19025782250.129
monovalent inorganic cation transportGO:0015672420.127
regulation of nucleobase containing compound metabolic processGO:00192192500.115
negative regulation of cellular processGO:00485232830.103
synaptic growth at neuromuscular junctionGO:005112420.103
regulation of nucleic acid templated transcriptionGO:19035062130.100
specification of symmetryGO:00097992040.097
cellular macromolecule metabolic processGO:00442603910.095
tube morphogenesisGO:00352393490.095
heart developmentGO:00075073130.093
negative regulation of biological processGO:00485193040.092
metal ion transportGO:0030001580.090
regulation of synaptic growth at neuromuscular junctionGO:000858210.090
regulation of metabolic processGO:00192223590.088
determination of bilateral symmetryGO:00098552040.088
signal transductionGO:00071654550.084
aromatic compound biosynthetic processGO:00194382170.084
larval developmentGO:000216420.080
cell projection morphogenesisGO:00488582440.079
establishment of endothelial barrierGO:006102830.079
regulation of cellular macromolecule biosynthetic processGO:20001122220.075
chordate embryonic developmentGO:00430092710.072
sensory organ developmentGO:00074233930.070
cilium morphogenesisGO:0060271850.066
regulation of synapse assemblyGO:005196330.064
neuromast primordium migrationGO:0048883120.064
regulation of nitrogen compound metabolic processGO:00511712510.063
cell morphogenesis involved in differentiationGO:00009041950.061
embryonic organ developmentGO:00485683810.060
single organism transportGO:00447652060.060
retina development in camera type eyeGO:00600411460.059
nucleobase containing compound metabolic processGO:00061392740.058
response to endogenous stimulusGO:0009719830.057
regulation of multicellular organismal developmentGO:20000262230.057
regulation of anatomical structure morphogenesisGO:00226031300.057
transportGO:00068102200.057
cellular nitrogen compound metabolic processGO:00346412900.057
localization of cellGO:00516742440.056
cellular component movementGO:00069283350.054
endocrine processGO:005088620.054
regulation of primary metabolic processGO:00800903110.053
determination of left right symmetryGO:00073681790.051
regulation of transcription dna templatedGO:00063552130.051
immune system processGO:00023762410.051
protein polymerizationGO:005125840.050
hemopoiesisGO:00300971830.050
cell morphogenesisGO:00009022890.050
heart morphogenesisGO:00030071560.050
regulation of signal transductionGO:00099662250.049
establishment of localizationGO:00512342440.048
cognitionGO:005089010.048
heterocycle metabolic processGO:00464832900.048
regulation of cellular metabolic processGO:00313233200.047
rna biosynthetic processGO:00327741810.047
regulation of developmental processGO:00507932470.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.046
response to alkaloidGO:004327920.045
cell projection organizationGO:00300302840.045
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.045
regulation of response to stimulusGO:00485832690.044
phosphorus metabolic processGO:00067931090.043
cellular aromatic compound metabolic processGO:00067252950.042
regulation of protein complex assemblyGO:004325430.042
growthGO:00400071740.041
response to chemicalGO:00422213200.041
cellular component morphogenesisGO:00329893360.041
generation of neuronsGO:00486993850.040
digestive tract morphogenesisGO:00485462310.039
gastrulationGO:00073692080.039
taxisGO:00423301090.039
nitrogen compound metabolic processGO:00068073190.039
homeostatic processGO:00425921420.039
regulation of cell shapeGO:000836010.038
microtubule based movementGO:0007018330.037
cell motilityGO:00488702440.037
nucleic acid metabolic processGO:00903042440.037
adult behaviorGO:003053420.037
transcription dna templatedGO:00063511810.036
cellular response to chemical stimulusGO:00708871570.036
positive regulation of cellular processGO:00485222010.036
regulation of endocrine processGO:004406020.036
cation homeostasisGO:0055080330.035
lateral inhibitionGO:004633110.035
regulation of dendrite morphogenesisGO:004881430.035
nucleobase containing compound biosynthetic processGO:00346542050.035
locomotionGO:00400113130.035
positive regulation of transportGO:005105020.034
cranial nerve developmentGO:0021545420.034
regulation of macromolecule biosynthetic processGO:00105562250.033
determination of heart left right asymmetryGO:00613711170.032
rna metabolic processGO:00160702190.031
cellular response to organic substanceGO:00713101050.031
chemical homeostasisGO:0048878490.031
guanosine containing compound catabolic processGO:190106920.030
response to organic substanceGO:00100331530.030
embryonic heart tube morphogenesisGO:00031431080.030
neuron projection developmentGO:00311751800.030
inorganic ion transmembrane transportGO:0098660570.030
neuron developmentGO:00486662620.030
developmental growthGO:00485891660.029
regionalizationGO:00030022740.029
cation transportGO:0006812810.028
cellular component disassemblyGO:002241110.028
enzyme linked receptor protein signaling pathwayGO:00071671060.028
positive regulation of cytoskeleton organizationGO:005149530.027
synaptic vesicle transportGO:004848910.027
regulation of transmembrane transporter activityGO:002289820.027
rna modificationGO:000945120.027
ion transportGO:00068111140.027
developmental programmed cell deathGO:001062340.026
regulation of jak stat cascadeGO:004642530.026
ion transmembrane transportGO:0034220910.026
regulation of cellular biosynthetic processGO:00313262450.026
regulation of synapse organizationGO:005080730.026
blood vessel developmentGO:00015682460.026
regulation of circadian rhythmGO:004275240.025
regulation of rna biosynthetic processGO:20011412130.025
regulation of metal ion transportGO:001095940.025
chemotaxisGO:00069351040.025
positive regulation of metabolic processGO:00098931080.025
organelle organizationGO:00069962270.025
single organism cell adhesionGO:0098602290.025
positive regulation of cellular component biogenesisGO:004408930.025
regulation of cell migrationGO:0030334400.025
regulation of localizationGO:00328791040.024
amine metabolic processGO:000930820.024
single organism organelle organizationGO:19025891990.024
regulation of protein complex disassemblyGO:004324410.024
organic cyclic compound metabolic processGO:19013603010.024
cellular component biogenesisGO:00440851780.024
response to stressGO:00069502630.024
cell migrationGO:00164772370.023
cell part morphogenesisGO:00329902460.023
cellular component assemblyGO:00226071700.023
purine nucleoside monophosphate catabolic processGO:000912840.023
nucleic acid templated transcriptionGO:00976591810.023
gene expressionGO:00104672520.023
digestive tract developmentGO:00485652650.023
regulation of molecular functionGO:0065009700.022
heterocycle biosynthetic processGO:00181302150.022
microtubule polymerization or depolymerizationGO:003110930.022
regulation of cytokine productionGO:000181730.022
organophosphate metabolic processGO:0019637370.022
cellular localizationGO:0051641970.022
negative regulation of cell projection organizationGO:003134590.022
neural crest cell developmentGO:0014032620.022
carbohydrate homeostasisGO:003350010.022
positive regulation of catabolic processGO:000989640.022
peptidyl threonine modificationGO:001821010.022
regulation of apoptotic processGO:0042981980.022
cellular response to endogenous stimulusGO:0071495680.022
regulation of cell communicationGO:00106462320.021
negative regulation of multicellular organismal processGO:0051241690.021
cell cell signalingGO:0007267520.021
synaptic vesicle localizationGO:009747910.021
positive regulation of protein complex assemblyGO:003133420.021
microtubule based processGO:0007017600.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
biological adhesionGO:0022610400.021
embryonic heart tube developmentGO:00350501330.021
response to abiotic stimulusGO:00096281220.021
ameboidal type cell migrationGO:00016671430.021
mesenchymal cell developmentGO:0014031780.020
exocytosisGO:000688710.020
macromolecular complex disassemblyGO:003298410.020
regulation of cell activationGO:005086510.020
cellular protein metabolic processGO:00442671290.020
regulation of biosynthetic processGO:00098892500.020
reflexGO:006000420.020
regulation of macromolecule metabolic processGO:00602553170.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
tyrosine phosphorylation of stat proteinGO:000726010.020
neuron projection morphogenesisGO:00488121610.020
regulation of synaptic plasticityGO:004816710.020
gtp metabolic processGO:004603940.019
cell deathGO:00082191210.019
regulation of reproductive processGO:200024140.019
response to other organismGO:0051707970.019
atp catabolic processGO:000620040.019
protein dephosphorylationGO:000647030.019
transmembrane transportGO:00550851200.019
agingGO:000756820.019
guanosine containing compound metabolic processGO:190106840.019
protein complex disassemblyGO:004324110.019
camera type eye developmentGO:00430102220.019
immune system developmentGO:00025201910.019
neurotransmitter transportGO:000683620.019
regulation of purine nucleotide catabolic processGO:003312120.019
regulation of filopodium assemblyGO:005148920.019
positive regulation of cellular catabolic processGO:003133130.018
g protein coupled receptor signaling pathwayGO:0007186740.018
cortical cytoskeleton organizationGO:003086510.018
establishment of protein localization to plasma membraneGO:009000210.018
central nervous system developmentGO:00074173870.018
divalent inorganic cation homeostasisGO:0072507220.018
small molecule metabolic processGO:0044281770.018
pronephros developmentGO:0048793690.018
negative regulation of cell deathGO:0060548600.018
response to light stimulusGO:0009416460.018
regulation of system processGO:0044057400.018
regulation of establishment of protein localizationGO:007020140.018
response to hormoneGO:0009725480.018
protein metabolic processGO:00195381830.018
stem cell differentiationGO:00488631170.017
negative regulation of kinase activityGO:003367340.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
regulation of cellular response to growth factor stimulusGO:0090287350.017
positive regulation of cellular metabolic processGO:0031325940.017
establishment of synaptic vesicle localizationGO:009748010.017
phosphate containing compound metabolic processGO:00067961080.017
cytoskeleton organizationGO:0007010960.017
cortical actin cytoskeleton organizationGO:003086610.017
post golgi vesicle mediated transportGO:000689210.017
macromolecule modificationGO:00434121110.017
regulation of photoreceptor cell differentiationGO:004653220.017
macromolecule biosynthetic processGO:00090592270.017
positive regulation of biological processGO:00485182530.016
regulation of protein transportGO:005122330.016
regulation of gene expressionGO:00104682650.016
response to oxygen containing compoundGO:1901700550.016
lateral line system developmentGO:0048925760.016
negative regulation of nitrogen compound metabolic processGO:0051172590.016
axonogenesisGO:00074091520.016
epithelial cell developmentGO:0002064420.016
head developmentGO:00603223030.016
erythrocyte homeostasisGO:0034101550.016
negative regulation of signal transductionGO:0009968940.016
negative regulation of stem cell differentiationGO:200073720.016
fibroblast growth factor receptor signaling pathwayGO:0008543220.015
morphogenesis of an epithelial sheetGO:0002011490.015
apoptotic processGO:00069151160.015
organonitrogen compound metabolic processGO:1901564740.015
single organism metabolic processGO:00447102170.015
epiboly involved in gastrulation with mouth forming secondGO:0055113350.015
phagocytosisGO:000690930.015
actin polymerization or depolymerizationGO:000815420.015
organic substance biosynthetic processGO:19015762890.015
peptidyl threonine phosphorylationGO:001810710.015
calcium ion dependent exocytosisGO:001715610.015
positive regulation of protein polymerizationGO:003227320.015
detection of mechanical stimulus involved in sensory perception of soundGO:005091030.015
establishment of localization in cellGO:0051649770.015
epithelial cell differentiationGO:00308551160.015
glucose importGO:004632320.015
regulation of rna metabolic processGO:00512522240.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
system processGO:00030081850.014
positive regulation of jak stat cascadeGO:004642720.014
sensory perception of painGO:001923310.014
protein depolymerizationGO:005126110.014
mechanosensory lateral line system developmentGO:0048881490.014
membrane hyperpolarizationGO:006008110.014
response to carbohydrateGO:000974330.014
sensory perceptionGO:0007600390.014
organic cyclic compound biosynthetic processGO:19013622230.014
negative regulation of nucleobase containing compound metabolic processGO:0045934590.014
regulation of dendrite developmentGO:005077330.014
gland developmentGO:00487321430.014
cellular monovalent inorganic cation homeostasisGO:003000420.014
positive regulation of multi organism processGO:004390230.014
mitochondrion organizationGO:000700540.014
regulation of signalingGO:00230512350.014
anatomical structure arrangementGO:004853220.014
glucose homeostasisGO:004259310.014
tissue remodelingGO:004877140.014
regulation of cellular protein catabolic processGO:190336210.013
cellular macromolecule biosynthetic processGO:00346452240.013
cell proliferationGO:0008283800.013
embryonic organ morphogenesisGO:00485622740.013
regulation of nervous system developmentGO:0051960900.013
mesenchyme developmentGO:00604851270.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of protein polymerizationGO:003227120.013
neural tube patterningGO:0021532330.013
neural crest cell migrationGO:0001755420.013
myeloid cell homeostasisGO:0002262560.013
response to growth factorGO:0070848390.013
cellular component assembly involved in morphogenesisGO:00109271070.013
regulation of blood pressureGO:000821710.013
axon developmentGO:00615641660.013
response to uvGO:000941130.013
cell adhesionGO:0007155400.013
nucleoside monophosphate catabolic processGO:000912540.013
vasculature developmentGO:00019442780.013
regulation of protein depolymerizationGO:190187910.013
protein targeting to membraneGO:000661210.013
auditory receptor cell morphogenesisGO:000209340.013
eye developmentGO:00016542770.013
hormone secretionGO:004687920.013
golgi vesicle transportGO:004819330.013
erythrocyte differentiationGO:0030218540.013
neuron differentiationGO:00301823530.013
regulation of protein catabolic processGO:004217610.013
cellular protein complex assemblyGO:0043623190.013
regulation of cellular component organizationGO:0051128860.013
cellular response to biotic stimulusGO:007121630.013
nuclear exportGO:005116810.013
mesenchymal cell differentiationGO:0048762870.013
muscle structure developmentGO:00610611960.013
production of molecular mediator of immune responseGO:000244020.013
primitive hemopoiesisGO:0060215270.012
alcohol biosynthetic processGO:004616520.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
autophagyGO:000691440.012
response to monosaccharideGO:003428430.012
renal system developmentGO:0072001940.012
peptide metabolic processGO:000651810.012
regulation of cell deathGO:00109411030.012
organic acid metabolic processGO:0006082310.012
organic substance transportGO:0071702580.012
deathGO:00162651210.012
regulation of growth rateGO:004000910.012
regulation of rho protein signal transductionGO:003502320.012
regulation of nucleoside metabolic processGO:000911820.012
regulation of cellular amino acid metabolic processGO:000652100.012
ion homeostasisGO:0050801410.012
protein importGO:001703830.012
negative regulation of protein kinase activityGO:000646940.012
multicellular organismal response to stressGO:003355520.012
negative regulation of apoptotic processGO:0043066550.012
cellular response to oxygen levelsGO:007145310.012
positive regulation of response to stimulusGO:0048584800.012
embryonic hemopoiesisGO:0035162530.012
lymphangiogenesisGO:0001946250.012
programmed cell deathGO:00125011190.012
regulation of catalytic activityGO:0050790550.012
protein phosphorylationGO:0006468470.012
regulation of carbohydrate metabolic processGO:000610940.012
epidermis developmentGO:0008544480.012
epithelial cell morphogenesisGO:000338220.012
sodium ion transmembrane transportGO:0035725210.012
endocrine hormone secretionGO:006098620.012
regulation of cell morphogenesis involved in differentiationGO:0010769380.012
ribosomal small subunit biogenesisGO:004227420.011
potassium ion transmembrane transportGO:0071805100.011
regulation of exocytosisGO:001715710.011
skin developmentGO:0043588540.011
single fertilizationGO:000733830.011
cation transmembrane transportGO:0098655650.011
skeletal system morphogenesisGO:00487051020.011
phosphorylationGO:0016310690.011
axonal defasciculationGO:000741420.011
regulation of programmed cell deathGO:00430671010.011
regulation of transporter activityGO:003240920.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
somatic stem cell maintenanceGO:003501910.011
cellular response to nutrient levelsGO:003166920.011
regulation of organ growthGO:004662030.011
cellular response to fibroblast growth factor stimulusGO:0044344220.011
response to fibroblast growth factorGO:0071774220.011
sodium ion transportGO:0006814240.011
developmental growth involved in morphogenesisGO:0060560860.011
protein complex assemblyGO:0006461300.011
protein secretionGO:000930610.011
protein complex subunit organizationGO:0071822460.011
synaptic vesicle endocytosisGO:004848810.011
interspecies interaction between organismsGO:004441940.011
rna localizationGO:000640340.011
response to hydrogen peroxideGO:004254230.011
midbrain developmentGO:0030901280.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
protein modification processGO:00362111000.011
cellular amine metabolic processGO:004410620.010
negative chemotaxisGO:005091910.010
posterior lateral line neuromast primordium migrationGO:0048920120.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
cellular protein complex disassemblyGO:004362410.010
mitochondrial transportGO:000683920.010
segmentationGO:0035282970.010
startle responseGO:000196440.010
digestive system developmentGO:00551232890.010
response to salt stressGO:0009651100.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
cellular response to radiationGO:007147840.010
cell projection assemblyGO:0030031640.010
embryonic pattern specificationGO:0009880440.010
protein localization to plasma membraneGO:007265910.010
rostrocaudal neural tube patterningGO:0021903290.010
embryo development ending in birth or egg hatchingGO:00097922710.010

soul4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
hematopoietic system diseaseDOID:7400.028
immune system diseaseDOID:291400.028
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.015
organ system cancerDOID:005068600.013
nervous system diseaseDOID:86300.012
disease of metabolismDOID:001466700.010