Danio rerio

0 known processes

smad6a

SMAD family member 6a

(Aliases: smad6,madh6,wu:fb22g05)

smad6a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.289
Worm Fly
regulation of macromolecule metabolic processGO:00602553170.185
Human Zebrafish Fly
regulation of biosynthetic processGO:00098892500.184
Human Zebrafish Fly
cell motilityGO:00488702440.182
Zebrafish Fly
regulation of primary metabolic processGO:00800903110.135
Human Zebrafish Fly
aromatic compound biosynthetic processGO:00194382170.125
Human Zebrafish Fly
regulation of metabolic processGO:00192223590.125
Human Zebrafish Fly
rna biosynthetic processGO:00327741810.115
Human Zebrafish Fly
cellular nitrogen compound metabolic processGO:00346412900.106
Human Zebrafish Fly
regulation of rna biosynthetic processGO:20011412130.102
Human Zebrafish Fly
heterocycle biosynthetic processGO:00181302150.097
Human Zebrafish Fly
nucleic acid metabolic processGO:00903042440.095
Human Zebrafish Fly
regulation of transcription from rna polymerase ii promoterGO:00063571140.093
Human Zebrafish Fly
muscle structure developmentGO:00610611960.093
Fly
cell migrationGO:00164772370.093
Zebrafish Fly
cellular macromolecule metabolic processGO:00442603910.087
Human Zebrafish Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.086
Fly
nucleobase containing compound metabolic processGO:00061392740.086
Human Zebrafish Fly
cell surface receptor signaling pathwayGO:00071663250.085
Human Zebrafish Fly
heterocycle metabolic processGO:00464832900.084
Human Zebrafish Fly
regulation of cellular metabolic processGO:00313233200.083
Human Zebrafish Fly
cellular nitrogen compound biosynthetic processGO:00442712180.082
Human Zebrafish Fly
cell morphogenesis involved in differentiationGO:00009041950.082
Fly
locomotionGO:00400113130.077
Zebrafish Fly
actin polymerization or depolymerizationGO:000815420.076
negative regulation of biological processGO:00485193040.071
Human Zebrafish Fly
embryonic organ morphogenesisGO:00485622740.070
Zebrafish
regulation of rna metabolic processGO:00512522240.066
Human Zebrafish Fly
embryonic organ developmentGO:00485683810.066
Zebrafish
regulation of synapse assemblyGO:005196330.065
Fly
signal transductionGO:00071654550.064
Human Zebrafish Fly
morphogenesis of an epitheliumGO:00020093330.062
Zebrafish Fly
response to organic substanceGO:00100331530.062
Human Fly
determination of heart left right asymmetryGO:00613711170.060
Zebrafish
cellular biosynthetic processGO:00442492860.059
Human Zebrafish Fly
central nervous system developmentGO:00074173870.059
cellular component morphogenesisGO:00329893360.058
Fly
cell part morphogenesisGO:00329902460.058
Fly
nitrogen compound metabolic processGO:00068073190.056
Human Zebrafish Fly
heart developmentGO:00075073130.055
Zebrafish
gene expressionGO:00104672520.055
Human Zebrafish Fly
positive regulation of biological processGO:00485182530.054
Zebrafish
neuron differentiationGO:00301823530.054
Fly
regulation of signal transductionGO:00099662250.054
Human Zebrafish Fly
regulation of nucleic acid templated transcriptionGO:19035062130.054
Human Zebrafish Fly
negative regulation of cellular processGO:00485232830.053
Human Zebrafish Fly
regulation of cellular biosynthetic processGO:00313262450.052
Human Zebrafish Fly
cellular component movementGO:00069283350.052
Zebrafish Fly
outflow tract morphogenesisGO:000315110.052
biosynthetic processGO:00090582940.051
Human Zebrafish Fly
organic cyclic compound metabolic processGO:19013603010.051
Human Zebrafish Fly
regulation of bindingGO:005109830.050
regulation of response to stimulusGO:00485832690.050
Human Zebrafish Fly
regulation of macromolecule biosynthetic processGO:00105562250.049
Human Zebrafish Fly
cellular ketone metabolic processGO:0042180110.047
regulation of nitrogen compound metabolic processGO:00511712510.046
Human Zebrafish Fly
determination of bilateral symmetryGO:00098552040.046
Zebrafish
cell projection morphogenesisGO:00488582440.046
Fly
regulation of cell projection assemblyGO:006049140.046
positive regulation of cell adhesionGO:004578510.044
nucleic acid templated transcriptionGO:00976591810.043
Human Zebrafish Fly
regionalizationGO:00030022740.043
Human Zebrafish Fly
anterior posterior pattern specificationGO:00099521520.042
Fly
regulation of stem cell differentiationGO:200073640.042
neuron developmentGO:00486662620.042
Fly
regulation of signalingGO:00230512350.041
Human Zebrafish Fly
stem cell differentiationGO:00488631170.040
Fly
localization of cellGO:00516742440.040
Zebrafish Fly
regulation of transcription dna templatedGO:00063552130.040
Human Zebrafish Fly
lipid storageGO:001991510.040
rna metabolic processGO:00160702190.039
Human Zebrafish Fly
membrane invaginationGO:001032410.039
cardiac chamber developmentGO:0003205190.038
regulation of cell communicationGO:00106462320.038
Human Zebrafish Fly
regulation of gene expressionGO:00104682650.038
Human Zebrafish Fly
regulation of multicellular organism growthGO:004001440.038
protein polymerizationGO:005125840.037
striated muscle cell differentiationGO:00511461290.037
axon guidanceGO:0007411860.037
Fly
immune system processGO:00023762410.037
Human Zebrafish
glial cell migrationGO:000834730.037
regulation of cellular ketone metabolic processGO:001056570.036
regulation of protein bindingGO:004339330.036
amine metabolic processGO:000930820.035
regulation of cellular amino acid metabolic processGO:000652100.035
axonogenesisGO:00074091520.035
Fly
regulation of reproductive processGO:200024140.034
Zebrafish
regulation of synapse organizationGO:005080730.034
Fly
stem cell maintenanceGO:001982740.034
Fly
cellular macromolecule biosynthetic processGO:00346452240.034
Human Zebrafish Fly
neuron projection morphogenesisGO:00488121610.034
Fly
regulation of epithelial cell proliferationGO:005067830.033
transcription from rna polymerase ii promoterGO:0006366800.032
Human Zebrafish Fly
organic substance biosynthetic processGO:19015762890.032
Human Zebrafish Fly
chordate embryonic developmentGO:00430092710.032
head developmentGO:00603223030.031
synaptic target recognitionGO:000803910.030
cellular component assemblyGO:00226071700.030
Human Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
Human Zebrafish Fly
muscle tissue developmentGO:00605371100.030
lamellipodium organizationGO:009758110.030
regulation of cell shapeGO:000836010.029
cellular amino acid metabolic processGO:000652070.029
positive regulation of epithelial cell differentiationGO:003085820.029
positive regulation of cellular processGO:00485222010.029
Zebrafish
epithelial cell differentiationGO:00308551160.029
determination of left right symmetryGO:00073681790.029
Zebrafish
sensory organ developmentGO:00074233930.029
Zebrafish
cellular amine metabolic processGO:004410620.029
organic cyclic compound biosynthetic processGO:19013622230.029
Human Zebrafish Fly
striated muscle tissue developmentGO:00147061100.029
positive regulation of map kinase activityGO:004340630.028
myeloid cell differentiationGO:0030099860.028
Zebrafish
negative regulation of nucleic acid templated transcriptionGO:1903507450.028
Zebrafish
skeletal system morphogenesisGO:00487051020.028
septum transversum developmentGO:000334340.028
segmentationGO:0035282970.028
positive regulation of cellular component biogenesisGO:004408930.028
muscle cell differentiationGO:00426921390.027
renal system developmentGO:0072001940.027
Mouse Fly
cellular aromatic compound metabolic processGO:00067252950.027
Human Zebrafish Fly
negative regulation of signal transductionGO:0009968940.027
Human Fly
transcription dna templatedGO:00063511810.026
Human Zebrafish Fly
regulation of protein import into nucleusGO:004230620.026
cell morphogenesisGO:00009022890.026
Fly
negative regulation of cell communicationGO:0010648960.026
Human Fly
adult behaviorGO:003053420.026
regulation of protein polymerizationGO:003227120.026
protein localization to nucleusGO:003450430.026
cellular modified amino acid metabolic processGO:000657530.026
cardiac cell fate commitmentGO:006091110.025
response to fluid shear stressGO:003440520.025
Human
mesoderm developmentGO:0007498880.025
positive regulation of transportGO:005105020.025
blood circulationGO:0008015870.025
negative regulation of macromolecule metabolic processGO:0010605760.025
Human Zebrafish
muscle cell developmentGO:00550011150.025
cellular component assembly involved in morphogenesisGO:00109271070.025
maintenance of locationGO:005123540.024
retina development in camera type eyeGO:00600411460.024
mesenchyme developmentGO:00604851270.024
regulation of cell differentiationGO:00455951420.024
Zebrafish Fly
response to endogenous stimulusGO:0009719830.024
Human Fly
actin filament polymerizationGO:003004120.024
deathGO:00162651210.024
Human
positive regulation of cell substrate adhesionGO:001081110.024
positive regulation of metabolic processGO:00098931080.024
Zebrafish
convergent extensionGO:00600261180.023
Zebrafish
regulation of cellular amine metabolic processGO:003323800.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
Human Zebrafish Fly
heart loopingGO:0001947940.023
Zebrafish
stem cell developmentGO:0048864820.023
Fly
stem cell proliferationGO:007208940.023
negative regulation of metabolic processGO:0009892860.023
Human Zebrafish
hematopoietic or lymphoid organ developmentGO:00485341910.023
Zebrafish
embryonic heart tube developmentGO:00350501330.023
Zebrafish
dorsal ventral pattern formationGO:00099531250.023
Human Zebrafish
positive regulation of gene expressionGO:0010628710.023
Zebrafish
nucleobase containing compound biosynthetic processGO:00346542050.023
Human Zebrafish Fly
organonitrogen compound metabolic processGO:1901564740.022
phagocytosisGO:000690930.022
brain developmentGO:00074202930.022
organic acid metabolic processGO:0006082310.022
nuclear transportGO:005116940.022
somite developmentGO:0061053960.022
programmed cell deathGO:00125011190.022
Human
digestive tract developmentGO:00485652650.022
Zebrafish Fly
positive regulation of nitrogen compound metabolic processGO:0051173690.021
Zebrafish
regulation of protein localization to nucleusGO:190018020.021
positive regulation of transcription dna templatedGO:0045893570.021
Zebrafish
determination of ventral identityGO:0048264210.021
Zebrafish
regulation of cell activationGO:005086510.021
neuron projection guidanceGO:0097485860.021
Fly
stem cell divisionGO:001714510.021
cardiac muscle cell differentiationGO:0055007300.021
single organism nuclear importGO:190259330.021
response to chemicalGO:00422213200.021
Human Fly
small molecule catabolic processGO:004428230.020
embryo development ending in birth or egg hatchingGO:00097922710.020
circulatory system processGO:0003013870.020
connective tissue developmentGO:0061448990.020
skeletal system developmentGO:00015011810.020
guanosine containing compound metabolic processGO:190106840.020
g1 s transition of mitotic cell cycleGO:000008210.020
proepicardium developmentGO:000334240.020
protein metabolic processGO:00195381830.020
Human
regulation of locomotionGO:0040012550.020
synaptic growth at neuromuscular junctionGO:005112420.020
Fly
wound healingGO:0042060900.019
eye developmentGO:00016542770.019
positive regulation of macromolecule metabolic processGO:0010604930.019
Zebrafish
regulation of protein complex assemblyGO:004325430.019
Human
cell projection organizationGO:00300302840.019
Fly
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
phagocytosis engulfmentGO:000691110.019
regulation of dendrite developmentGO:005077330.019
digestive system developmentGO:00551232890.019
Zebrafish Fly
cellular protein metabolic processGO:00442671290.019
Human
embryonic heart tube morphogenesisGO:00031431080.019
Zebrafish
regulation of cytokine productionGO:000181730.019
negative regulation of gene expressionGO:0010629650.019
Zebrafish
forebrain developmentGO:0030900960.019
hemopoiesisGO:00300971830.019
Zebrafish
negative regulation of nucleobase containing compound metabolic processGO:0045934590.019
Zebrafish
negative regulation of striated muscle tissue developmentGO:004584320.019
apoptotic process involved in developmentGO:190274220.019
protein targeting to nucleusGO:004474430.019
urogenital system developmentGO:0001655970.019
Mouse Fly
specification of symmetryGO:00097992040.019
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
Zebrafish
muscle organ developmentGO:00075171010.018
Fly
olfactory lobe developmentGO:002198840.018
negative regulation of rna biosynthetic processGO:1902679450.018
Zebrafish
carboxylic acid metabolic processGO:0019752220.018
embryonic limb morphogenesisGO:003032620.018
kidney developmentGO:0001822920.018
Mouse
nuclear importGO:005117030.018
gtp catabolic processGO:000618420.018
ribonucleoside monophosphate catabolic processGO:000915840.018
neural crest cell differentiationGO:0014033720.018
negative regulation of protein phosphorylationGO:000193340.017
Human
nucleocytoplasmic transportGO:000691340.017
macromolecule modificationGO:00434121110.017
Human
ventricular cardiac muscle tissue morphogenesisGO:005501020.017
calcium ion importGO:007050940.017
regulation of anatomical structure morphogenesisGO:00226031300.017
Zebrafish
axon developmentGO:00615641660.017
Fly
gland developmentGO:00487321430.017
negative regulation of transcription dna templatedGO:0045892450.017
Zebrafish
developmental growthGO:00485891660.017
Fly
proteasomal protein catabolic processGO:001049820.017
positive regulation of dna metabolic processGO:005105410.017
regulation of multicellular organismal processGO:00512392770.017
Zebrafish Fly
activation of mapk activityGO:000018730.017
lamellipodium assemblyGO:003003210.017
neuron projection developmentGO:00311751800.017
Fly
cellular response to organic substanceGO:00713101050.017
Human Fly
extrinsic apoptotic signaling pathwayGO:009719130.016
negative regulation of cell deathGO:0060548600.016
Human
somatic muscle developmentGO:000752540.016
striated muscle cell developmentGO:00550021080.016
camera type eye developmentGO:00430102220.016
response to corticosteroidGO:003196010.016
negative regulation of signalingGO:0023057960.016
Human Fly
meiotic nuclear divisionGO:000712640.016
germ line stem cell maintenanceGO:003071820.016
Fly
alpha amino acid metabolic processGO:190160530.016
epithelial tube morphogenesisGO:00605621480.016
Zebrafish Fly
digestive tract morphogenesisGO:00485462310.016
Zebrafish Fly
cell fate commitmentGO:0045165990.016
regulation of bone mineralizationGO:003050020.016
heart valve formationGO:000318840.016
cellular component biogenesisGO:00440851780.016
Human Fly
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
Fly
negative regulation of biosynthetic processGO:0009890550.016
Zebrafish
negative regulation of synapse assemblyGO:005196420.016
Fly
multicellular organism growthGO:003526440.015
cardiac chamber morphogenesisGO:0003206120.015
apoptotic processGO:00069151160.015
Human
positive regulation of cellular biosynthetic processGO:0031328680.015
Zebrafish
establishment of protein localization to organelleGO:007259440.015
photoreceptor cell fate commitmentGO:004655210.015
chemosensory behaviorGO:000763510.015
regulation of purine nucleotide catabolic processGO:003312120.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
Zebrafish
cardiac muscle tissue developmentGO:0048738480.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
regulation of gtp catabolic processGO:003312420.015
somitogenesisGO:0001756870.015
mesenchymal cell differentiationGO:0048762870.015
positive regulation of cellular catabolic processGO:003133130.015
regulation of biomineral tissue developmentGO:007016720.015
endoderm developmentGO:0007492490.015
oxoacid metabolic processGO:0043436310.015
cellular component disassemblyGO:002241110.015
heart morphogenesisGO:00030071560.015
Zebrafish
cell projection assemblyGO:0030031640.014
regulation of intracellular protein transportGO:003315730.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.014
Zebrafish
regulation of establishment of protein localizationGO:007020140.014
regulation of chondrocyte differentiationGO:003233010.014
negative regulation of muscle tissue developmentGO:190186220.014
cellular response to extracellular stimulusGO:003166820.014
macromolecular complex disassemblyGO:003298410.014
rhombomere morphogenesisGO:0021593170.014
cellular response to biotic stimulusGO:007121630.014
positive regulation of catabolic processGO:000989640.014
lateral inhibitionGO:004633110.014
development of primary female sexual characteristicsGO:004654540.014
heart valve morphogenesisGO:000317980.014
catechol containing compound biosynthetic processGO:000971320.014
ameboidal type cell migrationGO:00016671430.014
Zebrafish
rhombomere formationGO:0021594120.014
establishment of endothelial barrierGO:006102830.014
negative regulation of response to stimulusGO:00485851040.014
Human Fly
taxisGO:00423301090.014
Fly
regulation of filopodium assemblyGO:005148920.014
negative regulation of cellular metabolic processGO:0031324770.014
Human Zebrafish
response to external stimulusGO:00096052640.014
Worm Fly
negative regulation of kinase activityGO:003367340.013
organelle assemblyGO:00709251100.013
negative chemotaxisGO:005091910.013
protein importGO:001703830.013
cranial nerve developmentGO:0021545420.013
heart joggingGO:0003146400.013
Zebrafish
regulation of multicellular organismal developmentGO:20000262230.013
Zebrafish Fly
regulation of programmed cell deathGO:00430671010.013
Human
camera type eye morphogenesisGO:00485931080.013
skin developmentGO:0043588540.013
cellular response to growth factor stimulusGO:0071363390.013
Human Fly
regulation of cellular protein metabolic processGO:0032268520.013
Human
positive regulation of apoptotic signaling pathwayGO:200123510.013
cell cycle g1 s phase transitionGO:004484310.013
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.013
mechanosensory behaviorGO:000763820.013
regulation of epithelial to mesenchymal transitionGO:001071730.013
cortical actin cytoskeleton organizationGO:003086610.013
heart processGO:0003015710.013
olfactory bulb developmentGO:002177240.013
lymphocyte proliferationGO:004665110.013
cell matrix adhesionGO:000716040.013
positive regulation of rna metabolic processGO:0051254590.012
Zebrafish
angiogenesisGO:00015251580.012
agingGO:000756820.012
regulation of developmental processGO:00507932470.012
Zebrafish Fly
positive regulation of cell cycleGO:004578730.012
regulation of nucleoside metabolic processGO:000911820.012
central nervous system neuron differentiationGO:0021953740.012
growthGO:00400071740.012
Fly
response to stressGO:00069502630.012
Human
negative regulation of protein kinase activityGO:000646940.012
nerve developmentGO:0021675450.012
single organism metabolic processGO:00447102170.012
cellular response to hormone stimulusGO:0032870390.012
cognitionGO:005089010.012
negative regulation of cell differentiationGO:0045596460.012
Fly
regulation of protein transportGO:005122330.012
intracellular signal transductionGO:0035556850.012
Human Zebrafish Fly
macromolecule biosynthetic processGO:00090592270.012
Human Zebrafish Fly
regulation of organ growthGO:004662030.012
myofibril assemblyGO:0030239480.012
cellular protein complex assemblyGO:0043623190.012
Human
negative regulation of epithelial cell proliferationGO:005068010.012
small molecule metabolic processGO:0044281770.012
regulation of cell deathGO:00109411030.012
Human
homeostatic processGO:00425921420.012
blood vessel developmentGO:00015682460.012
Zebrafish
cellular response to nutrient levelsGO:003166920.012
regulation of endothelial cell differentiationGO:004560130.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
Human Zebrafish Fly
lateral line system developmentGO:0048925760.011
vasculature developmentGO:00019442780.011
Zebrafish
negative regulation of muscle cell differentiationGO:005114810.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
Human Zebrafish Fly
protein import into nucleusGO:000660630.011
cortical cytoskeleton organizationGO:003086510.011
establishment of blood brain barrierGO:006085620.011
peptidyl threonine phosphorylationGO:001810710.011
specification of organ identityGO:001009220.011
gliogenesisGO:0042063450.011
negative regulation of programmed cell deathGO:0043069580.011
Human
positive regulation of cytoskeleton organizationGO:005149530.011
generation of neuronsGO:00486993850.011
Fly
regulation of apoptotic processGO:0042981980.011
Human
phosphate containing compound metabolic processGO:00067961080.011
Human Fly
regulation of cell substrate adhesionGO:001081010.011
cytokinesisGO:000091030.011
positive regulation of response to stimulusGO:0048584800.011
response to woundingGO:00096111160.011
cellular response to lipopolysaccharideGO:007122230.011
cardiocyte differentiationGO:0035051440.011
cellular response to external stimulusGO:007149620.011
germ line stem cell divisionGO:004207810.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of biological qualityGO:00650082630.011
Fly
cell adhesion mediated by integrinGO:003362710.011
catechol containing compound metabolic processGO:000971220.011
gastrulationGO:00073692080.011
Zebrafish
modification dependent protein catabolic processGO:001994130.011
regulation of cytoplasmic transportGO:190364940.011
cartilage developmentGO:0051216960.011
sensory system developmentGO:0048880760.011
trabecula morphogenesisGO:006138320.011
catecholamine biosynthetic processGO:004242320.011
rhombomere 5 developmentGO:002157140.011
tube morphogenesisGO:00352393490.011
Zebrafish Fly
determination of dorsal ventral asymmetryGO:0048262340.010
Zebrafish
sensory organ morphogenesisGO:00905962000.010
Zebrafish
secondary metabolic processGO:001974830.010
dorsal convergenceGO:0060030140.010
Zebrafish
positive regulation of nucleotide catabolic processGO:003081310.010
cellular protein modification processGO:00064641000.010
Human
heart field specificationGO:000312810.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
monocyte differentiationGO:003022420.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
carbohydrate homeostasisGO:003350010.010
rna localizationGO:000640340.010
left right pattern formationGO:0060972190.010
hindbrain developmentGO:0030902910.010
embryonic pattern specificationGO:0009880440.010
Human Zebrafish
myeloid cell developmentGO:0061515320.010
Zebrafish
positive regulation of protein polymerizationGO:003227320.010
response to lipidGO:0033993600.010
blood vessel morphogenesisGO:00485142160.010
Zebrafish
leukocyte proliferationGO:007066110.010
regulation of molecular functionGO:0065009700.010
skeletal muscle organ developmentGO:0060538780.010
positive regulation of reproductive processGO:200024320.010
Zebrafish
regulation of cellular component movementGO:0051270550.010

smad6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
Human
musculoskeletal system diseaseDOID:1700.016
physical disorderDOID:008001500.011
nervous system diseaseDOID:86300.011