Danio rerio

0 known processes

ctsc

cathepsin C

(Aliases: ik:tdsubc_1h2,wu:fb34g12,cb912,wu:fj58d01,sb:cb146)

ctsc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein catabolic processGO:004425740.637
Rat
proteolysis involved in cellular protein catabolic processGO:005160330.626
Rat
larval developmentGO:000216420.350
establishment of localizationGO:00512342440.282
response to organic substanceGO:00100331530.175
Rat
multicellular organismal macromolecule metabolic processGO:004425920.169
collagen metabolic processGO:003296320.168
response to external stimulusGO:00096052640.161
positive regulation of cellular extravasationGO:000269310.158
lipid storageGO:001991510.123
muscle structure developmentGO:00610611960.122
organic substance catabolic processGO:1901575280.107
Rat
lymph vessel morphogenesisGO:0036303250.105
autophagyGO:000691440.104
response to abiotic stimulusGO:00096281220.100
regulation of blood vessel sizeGO:005088020.096
response to nutrientGO:000758430.095
tissue regenerationGO:0042246740.094
organonitrogen compound metabolic processGO:1901564740.087
regulation of cell communicationGO:00106462320.083
Mouse
taxisGO:00423301090.082
positive regulation of catabolic processGO:000989640.082
Rat
response to carbohydrateGO:000974330.080
gtp metabolic processGO:004603940.077
guanosine containing compound metabolic processGO:190106840.075
small molecule metabolic processGO:0044281770.074
tube morphogenesisGO:00352393490.073
regulation of syncytium formation by plasma membrane fusionGO:006014220.071
response to hexoseGO:000974630.069
regulation of primary metabolic processGO:00800903110.068
Mouse Rat
regulation of nitrogen compound metabolic processGO:00511712510.067
regulation of metabolic processGO:00192223590.066
Mouse Rat
guanosine containing compound catabolic processGO:190106920.065
multicellular organismal metabolic processGO:004423620.063
signal transductionGO:00071654550.061
Mouse
cell morphogenesisGO:00009022890.060
developmental growthGO:00485891660.058
positive regulation of transportGO:005105020.056
nucleobase containing compound metabolic processGO:00061392740.056
regulation of neutrophil migrationGO:190262260.056
cell surface receptor signaling pathwayGO:00071663250.056
immune system processGO:00023762410.055
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.053
establishment or maintenance of cell polarityGO:0007163290.052
camera type eye developmentGO:00430102220.052
glycosyl compound metabolic processGO:1901657110.051
cellular protein metabolic processGO:00442671290.051
Mouse Rat
nucleobase containing small molecule metabolic processGO:0055086320.050
immune responseGO:0006955280.050
Mouse
transportGO:00068102200.050
multicellular organism growthGO:003526440.050
neuron differentiationGO:00301823530.049
cellular catabolic processGO:0044248270.049
Rat
tissue remodelingGO:004877140.049
oxidoreduction coenzyme metabolic processGO:000673310.047
blood vessel morphogenesisGO:00485142160.047
Zebrafish
regulation of signalingGO:00230512350.045
Mouse
purine nucleotide metabolic processGO:0006163270.044
response to monosaccharideGO:003428430.044
negative regulation of biological processGO:00485193040.044
blood vessel developmentGO:00015682460.044
Zebrafish
fin regenerationGO:0031101510.043
multi organism processGO:00517041340.043
programmed cell deathGO:00125011190.043
Mouse
regulation of multicellular organismal processGO:00512392770.042
muscle organ developmentGO:00075171010.042
cellular aldehyde metabolic processGO:000608140.042
nucleoside phosphate metabolic processGO:0006753280.042
gtp catabolic processGO:000618420.041
response to phGO:000926820.041
gene expressionGO:00104672520.041
system processGO:00030081850.040
regenerationGO:0031099910.040
amine metabolic processGO:000930820.040
epithelial cell differentiationGO:00308551160.040
angiogenesisGO:00015251580.040
Zebrafish
smooth muscle contractionGO:000693920.039
agingGO:000756820.039
Rat
response to stressGO:00069502630.039
cellular aromatic compound metabolic processGO:00067252950.039
morphogenesis of an epitheliumGO:00020093330.039
modification dependent protein catabolic processGO:001994130.038
generation of neuronsGO:00486993850.038
branching morphogenesis of an epithelial tubeGO:0048754150.038
positive regulation of cgmp biosynthetic processGO:003082860.038
nitrogen compound metabolic processGO:00068073190.037
cellular macromolecule catabolic processGO:0044265120.037
Rat
neuron projection developmentGO:00311751800.037
establishment of protein localization to organelleGO:007259440.037
regulation of dendrite developmentGO:005077330.037
positive regulation of gtp catabolic processGO:003312610.037
response to glucoseGO:000974930.036
regulation of biological qualityGO:00650082630.036
blood circulationGO:0008015870.035
circulatory system processGO:0003013870.035
regulation of tube sizeGO:003515020.035
regulation of synapse assemblyGO:005196330.035
regulation of response to stimulusGO:00485832690.035
Mouse
organic cyclic compound metabolic processGO:19013603010.034
ribonucleotide metabolic processGO:0009259270.034
peptide metabolic processGO:000651810.033
maintenance of locationGO:005123540.033
cellular nitrogen compound metabolic processGO:00346412900.033
regulation of cell shapeGO:000836010.032
cellular component disassemblyGO:002241110.032
regulation of synaptic growth at neuromuscular junctionGO:000858210.032
cellular component morphogenesisGO:00329893360.032
cell motilityGO:00488702440.031
oxalate transportGO:001953210.031
response to chemicalGO:00422213200.030
Rat
developmental cell growthGO:0048588520.030
hematopoietic stem cell migrationGO:003570140.029
regulation of blood pressureGO:000821710.029
sulfate transmembrane transportGO:190235820.029
interspecies interaction between organismsGO:004441940.029
single organism metabolic processGO:00447102170.028
proteolysisGO:0006508380.028
Human Mouse Rat
regulation of cell activationGO:005086510.028
positive regulation of purine nucleotide catabolic processGO:003312310.028
cellular amino acid metabolic processGO:000652070.028
positive regulation of nucleoside metabolic processGO:004597910.028
axonogenesisGO:00074091520.027
response to bacteriumGO:0009617580.027
negative regulation of protein kinase activityGO:000646940.027
nucleic acid transportGO:005065720.027
response to woundingGO:00096111160.027
protein import into nucleusGO:000660630.027
regulation of leukocyte migrationGO:000268580.026
homeostasis of number of cells within a tissueGO:004887340.026
nuclear transportGO:005116940.026
purine containing compound metabolic processGO:0072521290.026
regulation of signal transductionGO:00099662250.026
Mouse
sequestering of calcium ionGO:005120830.026
protein targeting to nucleusGO:004474430.026
epithelial tube morphogenesisGO:00605621480.026
single organism membrane organizationGO:0044802200.026
cellular amide metabolic processGO:004360340.026
cell projection morphogenesisGO:00488582440.025
cell projection organizationGO:00300302840.025
heterocycle metabolic processGO:00464832900.025
regulation of anatomical structure morphogenesisGO:00226031300.025
response to amineGO:001407510.024
retina development in camera type eyeGO:00600411460.024
response to corticosteroidGO:003196010.024
axon developmentGO:00615641660.024
protein metabolic processGO:00195381830.024
Human Mouse Rat
regulation of gtpase activityGO:004308720.024
defense response to bacteriumGO:0042742220.024
neuron developmentGO:00486662620.024
catabolic processGO:0009056320.024
Rat
central nervous system developmentGO:00074173870.023
regulation of nucleotide catabolic processGO:003081120.023
striated muscle tissue developmentGO:00147061100.023
stem cell proliferationGO:007208940.023
purine ribonucleoside monophosphate catabolic processGO:000916940.023
positive regulation of nucleotide catabolic processGO:003081310.023
modification dependent macromolecule catabolic processGO:004363230.023
cellular component assemblyGO:00226071700.022
regulation of multicellular organism growthGO:004001440.022
wound healingGO:0042060900.022
negative regulation of rna splicingGO:003311910.022
g protein coupled receptor signaling pathwayGO:0007186740.022
ubiquitin dependent protein catabolic processGO:000651130.022
ribose phosphate metabolic processGO:0019693270.022
organic acid metabolic processGO:0006082310.022
cell part morphogenesisGO:00329902460.022
negative regulation of cellular metabolic processGO:0031324770.021
negative regulation of epithelial cell proliferationGO:005068010.021
superoxide metabolic processGO:000680120.021
regulation of cellular component organizationGO:0051128860.021
cellular biosynthetic processGO:00442492860.021
locomotionGO:00400113130.021
neutrophil mediated immunityGO:000244610.021
regulation of phGO:000688530.021
lytic vacuole organizationGO:008017110.021
positive regulation of exocytosisGO:004592110.020
glucose homeostasisGO:004259310.020
skeletal muscle organ developmentGO:0060538780.020
syncytium formationGO:0006949120.020
cellular component movementGO:00069283350.020
regulation of purine nucleotide catabolic processGO:003312120.020
positive regulation of gtpase activityGO:004354710.020
regulation of chemotaxisGO:0050920180.020
nucleoside triphosphate metabolic processGO:000914190.020
cellular macromolecule metabolic processGO:00442603910.019
Mouse Rat
positive regulation of secretion by cellGO:190353210.019
purine ribonucleotide metabolic processGO:0009150270.019
single organism catabolic processGO:0044712130.019
biological adhesionGO:0022610400.019
regulation of cell motilityGO:2000145460.019
nucleotide metabolic processGO:0009117280.019
brain developmentGO:00074202930.019
bone remodelingGO:004684920.019
negative regulation of mrna processingGO:005068610.019
positive regulation of cellular catabolic processGO:003133130.019
Rat
sexual reproductionGO:0019953360.018
cellular response to chemical stimulusGO:00708871570.018
ameboidal type cell migrationGO:00016671430.018
cellular response to extracellular stimulusGO:003166820.018
intracellular signal transductionGO:0035556850.018
regulation of metal ion transportGO:001095940.018
response to nicotineGO:003509420.018
muscle tissue developmentGO:00605371100.018
metal ion homeostasisGO:0055065260.018
meiotic cell cycle processGO:190304630.017
response to vitaminGO:003327330.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
regulation of synapse organizationGO:005080730.017
regulation of establishment of planar polarityGO:009017540.017
regulation of nucleoside metabolic processGO:000911820.017
positive regulation of cellular amine metabolic processGO:003324000.017
response to external biotic stimulusGO:0043207970.017
morphogenesis of a branching epitheliumGO:0061138160.017
multicellular organismal response to stressGO:003355520.017
phagosome maturationGO:009038210.017
regulation of gtp catabolic processGO:003312420.017
synaptic transmission cholinergicGO:000727140.017
small gtpase mediated signal transductionGO:000726480.016
regulation of muscle contractionGO:000693730.016
response to glucocorticoidGO:005138410.016
regulation of establishment of protein localizationGO:007020140.016
transmission of nerve impulseGO:0019226190.016
cellular response to external stimulusGO:007149620.016
negative regulation of muscle contractionGO:004593210.016
signal transduction in absence of ligandGO:003803410.016
somatic stem cell maintenanceGO:003501910.016
fatty acid transportGO:001590810.016
multicellular organismal reproductive processGO:0048609350.015
release of sequestered calcium ion into cytosolGO:005120930.015
retina morphogenesis in camera type eyeGO:0060042790.015
embryonic viscerocranium morphogenesisGO:0048703520.015
embryonic skeletal system developmentGO:0048706970.015
regulation of synaptic plasticityGO:004816710.015
regulation of localizationGO:00328791040.015
regulation of response to extracellular stimulusGO:003210410.015
calcium ion homeostasisGO:0055074190.015
organic substance transportGO:0071702580.015
chemotaxisGO:00069351040.015
endosome to lysosome transportGO:000833310.015
macromolecule biosynthetic processGO:00090592270.014
protein targeting to membraneGO:000661210.014
oxoacid metabolic processGO:0043436310.014
regulation of cytoplasmic transportGO:190364940.014
negative regulation of kinase activityGO:003367340.014
retinal metabolic processGO:004257430.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
negative regulation of protein phosphorylationGO:000193340.014
neurotransmitter secretionGO:000726920.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
nucleoside metabolic processGO:0009116110.014
ph reductionGO:004585110.014
macroautophagyGO:001623610.014
regulation of immune system processGO:0002682340.014
establishment of protein localization to plasma membraneGO:009000210.013
positive regulation of response to external stimulusGO:003210390.013
negative regulation of response to stimulusGO:00485851040.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
extracellular matrix organizationGO:0030198270.013
cell growthGO:0016049570.013
regulation of gene expressionGO:00104682650.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
cell migrationGO:00164772370.013
establishment of blood brain barrierGO:006085620.013
ion transportGO:00068111140.013
ion homeostasisGO:0050801410.013
negative regulation of synapse assemblyGO:005196420.013
carbohydrate derivative metabolic processGO:1901135610.013
response to endogenous stimulusGO:0009719830.013
heart rudiment formationGO:000331550.013
synaptic growth at neuromuscular junctionGO:005112420.013
regulation of cellular amine metabolic processGO:003323800.013
growthGO:00400071740.013
medulla oblongata developmentGO:002155040.013
phosphorus metabolic processGO:00067931090.013
single organism transportGO:00447652060.013
cognitionGO:005089010.013
positive regulation of myeloid cell differentiationGO:004563920.013
atp catabolic processGO:000620040.012
establishment of rna localizationGO:005123630.012
regulation of cell differentiationGO:00455951420.012
cation transportGO:0006812810.012
chemical homeostasisGO:0048878490.012
cellular hormone metabolic processGO:0034754190.012
macromolecule localizationGO:0033036540.012
nucleocytoplasmic transportGO:000691340.012
neutrophil extravasationGO:007267210.012
transcription dna templatedGO:00063511810.012
innate immune responseGO:0045087130.012
beta amyloid metabolic processGO:005043510.012
response to biotic stimulusGO:0009607970.012
cellular component biogenesisGO:00440851780.012
response to alkaloidGO:004327920.012
neutrophil migrationGO:1990266100.012
dorsal ventral pattern formationGO:00099531250.012
mitochondrion organizationGO:000700540.012
positive regulation of inflammatory responseGO:005072910.012
defense response to gram positive bacteriumGO:005083060.012
vasculature developmentGO:00019442780.011
Zebrafish
negative regulation of signalingGO:0023057960.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
endosomal transportGO:001619720.011
somatic muscle developmentGO:000752540.011
amino acid transportGO:000686520.011
regulation of bone remodelingGO:004685020.011
embryonic heart tube developmentGO:00350501330.011
nucleobase containing compound transportGO:001593120.011
extrinsic apoptotic signaling pathwayGO:009719130.011
rna transportGO:005065820.011
localization of cellGO:00516742440.011
carboxylic acid metabolic processGO:0019752220.011
positive regulation of cell activationGO:005086710.011
negative regulation of chromatin modificationGO:190330910.011
neurotransmitter transportGO:000683620.011
intracellular transportGO:0046907320.011
regulation of cellular protein catabolic processGO:190336210.011
Rat
defense response to gram negative bacteriumGO:005082980.011
protein localization to membraneGO:007265790.011
cellular response to starvationGO:000926710.011
regulation of oxidative stress induced cell deathGO:190320120.011
muscle cell differentiationGO:00426921390.011
cellular response to nutrient levelsGO:003166920.011
melanosome organizationGO:003243840.011
regulation of establishment or maintenance of cell polarityGO:003287820.011
regulation of cellular amino acid metabolic processGO:000652100.011
organelle assemblyGO:00709251100.011
organophosphate metabolic processGO:0019637370.011
negative regulation of cellular processGO:00485232830.011
regulation of protein localization to plasma membraneGO:190307610.011
purine ribonucleoside metabolic processGO:0046128100.010
regulation of cellular biosynthetic processGO:00313262450.010
positive regulation of secretionGO:005104710.010
protein localization to nucleusGO:003450430.010
myeloid leukocyte migrationGO:0097529120.010
protein acylationGO:004354330.010
purine ribonucleoside triphosphate metabolic processGO:000920590.010
terpenoid metabolic processGO:0006721150.010

ctsc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.342
disease of metabolismDOID:001466700.342
lysosomal storage diseaseDOID:321100.342
disease of anatomical entityDOID:700.124
Human
immune system diseaseDOID:291400.024
nervous system diseaseDOID:86300.023
primary immunodeficiency diseaseDOID:61200.023
lipid storage diseaseDOID:945500.021
brain diseaseDOID:93600.016
central nervous system diseaseDOID:33100.016
tauopathyDOID:68000.014
dementiaDOID:130700.014
neurodegenerative diseaseDOID:128900.014
alzheimer s diseaseDOID:1065200.014
disease of mental healthDOID:15000.014
cognitive disorderDOID:156100.014