Danio rerio

17 known processes

ctsz

cathepsin Z

(Aliases: zgc:103420,wu:fj81f10)

ctsz biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein catabolic processGO:004425740.526
proteolysis involved in cellular protein catabolic processGO:005160330.359
agingGO:000756820.232
larval developmentGO:000216420.179
Worm
response to chemicalGO:00422213200.178
regulation of multicellular organismal processGO:00512392770.177
regulation of multicellular organism growthGO:004001440.170
multicellular organism growthGO:003526440.134
collagen metabolic processGO:003296320.124
response to nicotineGO:003509420.118
organelle fusionGO:004828430.118
positive regulation of cellular catabolic processGO:003133130.112
response to alkaloidGO:004327920.106
leukocyte mediated cytotoxicityGO:000190910.098
regulation of tube sizeGO:003515020.098
blood vessel morphogenesisGO:00485142160.095
programmed cell deathGO:00125011190.092
response to external stimulusGO:00096052640.084
regulation of protein catabolic processGO:004217610.083
hydrogen peroxide metabolic processGO:004274320.081
positive regulation of transportGO:005105020.080
immune system developmentGO:00025201910.079
positive regulation of catabolic processGO:000989640.074
regulation of cell deathGO:00109411030.074
establishment of localizationGO:00512342440.073
multicellular organismal metabolic processGO:004423620.073
proteolysisGO:0006508380.072
multicellular organismal macromolecule metabolic processGO:004425920.072
response to organic substanceGO:00100331530.070
cell deathGO:00082191210.069
regulation of response to stimulusGO:00485832690.069
signal transductionGO:00071654550.068
monovalent inorganic cation homeostasisGO:005506790.068
single organism membrane fusionGO:004480120.067
response to amineGO:001407510.066
lipid storageGO:001991510.063
developmental growthGO:00485891660.062
deathGO:00162651210.062
vasculature developmentGO:00019442780.061
cell surface receptor signaling pathwayGO:00071663250.061
regulation of nucleotide catabolic processGO:003081120.060
positive regulation of biological processGO:00485182530.058
regulation of metal ion transportGO:001095940.058
negative regulation of multicellular organismal processGO:0051241690.057
cell killingGO:000190620.057
negative regulation of cellular processGO:00485232830.056
phagolysosome assemblyGO:000184510.056
negative regulation of biological processGO:00485193040.055
endosomal transportGO:001619720.055
regulation of signalingGO:00230512350.055
cellular protein metabolic processGO:00442671290.054
xenobiotic metabolic processGO:000680540.053
immune system processGO:00023762410.051
blood vessel developmentGO:00015682460.050
lytic vacuole organizationGO:008017110.050
single organism transportGO:00447652060.049
phagosome maturationGO:009038210.049
intracellular transportGO:0046907320.049
generation of neuronsGO:00486993850.048
lipid catabolic processGO:001604240.048
ion transportGO:00068111140.047
membrane fusionGO:006102520.046
maintenance of locationGO:005123540.046
regulation of apoptotic processGO:0042981980.046
regulation of blood vessel sizeGO:005088020.045
single organism metabolic processGO:00447102170.045
response to acidic phGO:001044720.044
vacuolar transportGO:000703420.042
single organism localizationGO:19025782250.042
superoxide metabolic processGO:000680120.041
macromolecule catabolic processGO:0009057150.041
angiogenesisGO:00015251580.041
regulation of blood pressureGO:000821710.041
transportGO:00068102200.039
regulation of cell communicationGO:00106462320.038
membrane lipid biosynthetic processGO:004646720.038
cellular monovalent inorganic cation homeostasisGO:003000420.038
organic substance catabolic processGO:1901575280.038
cellular component biogenesisGO:00440851780.038
vacuole organizationGO:000703390.038
apoptotic processGO:00069151160.037
protein metabolic processGO:00195381830.037
neuron differentiationGO:00301823530.036
neuron projection developmentGO:00311751800.036
response to nutrientGO:000758430.036
intramembranous ossificationGO:000195730.035
regulation of programmed cell deathGO:00430671010.035
regulation of intracellular phGO:005145310.035
establishment of synaptic vesicle localizationGO:009748010.034
signal transduction in absence of ligandGO:003803410.034
positive regulation of apoptotic signaling pathwayGO:200123510.034
synaptic vesicle endocytosisGO:004848810.032
cellular response to chemical stimulusGO:00708871570.032
glucose homeostasisGO:004259310.032
cellular response to lipopolysaccharideGO:007122230.032
extrinsic apoptotic signaling pathwayGO:009719130.031
organonitrogen compound metabolic processGO:1901564740.031
sphingolipid biosynthetic processGO:003014820.031
protein import into nucleusGO:000660630.031
response to endogenous stimulusGO:0009719830.030
cellular response to biotic stimulusGO:007121630.030
embryo development ending in birth or egg hatchingGO:00097922710.030
Worm
regulation of biological qualityGO:00650082630.030
regulation of cell activationGO:005086510.029
membrane organizationGO:0061024210.028
multi organism processGO:00517041340.028
smooth muscle contractionGO:000693920.028
amine metabolic processGO:000930820.028
response to monosaccharideGO:003428430.028
guanosine containing compound metabolic processGO:190106840.028
nuclear transportGO:005116940.028
protein catabolic processGO:003016370.028
cell morphogenesisGO:00009022890.027
regulation of growthGO:0040008420.027
response to alcoholGO:0097305140.027
cell motilityGO:00488702440.027
regulation of nucleocytoplasmic transportGO:004682220.027
ph reductionGO:004585110.027
regulation of inflammatory responseGO:005072720.027
cell projection organizationGO:00300302840.027
cellular component assemblyGO:00226071700.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.027
response to biotic stimulusGO:0009607970.026
regulation of cytoplasmic transportGO:190364940.026
autophagyGO:000691440.026
response to drugGO:004249330.026
nitrogen compound metabolic processGO:00068073190.026
oxidoreduction coenzyme metabolic processGO:000673310.025
axon developmentGO:00615641660.025
response to woundingGO:00096111160.025
regulation of response to oxidative stressGO:190288220.025
regulation of cellular phGO:003064110.025
regulation of phGO:000688530.024
organic acid metabolic processGO:0006082310.024
gtp catabolic processGO:000618420.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
negative regulation of signalingGO:0023057960.024
chemotaxisGO:00069351040.024
regulation of cell proliferationGO:0042127370.024
regulation of cytokine productionGO:000181730.024
regulation of proteolysisGO:0030162240.024
protein targeting to nucleusGO:004474430.024
organic substance transportGO:0071702580.023
nucleic acid transportGO:005065720.023
oxoacid metabolic processGO:0043436310.023
response to hydrogen peroxideGO:004254230.023
cellular macromolecule metabolic processGO:00442603910.023
direct ossificationGO:003607230.023
modification dependent protein catabolic processGO:001994130.023
reactive oxygen species metabolic processGO:007259360.023
hemopoiesisGO:00300971830.023
catabolic processGO:0009056320.023
synaptic vesicle recyclingGO:003646510.023
carboxylic acid metabolic processGO:0019752220.023
negative regulation of cell deathGO:0060548600.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.022
protein acetylationGO:000647320.022
axon regenerationGO:0031103140.022
regulation of establishment of protein localizationGO:007020140.022
nuclear importGO:005117030.021
rna localizationGO:000640340.021
regulation of developmental processGO:00507932470.021
regulation of bindingGO:005109830.021
positive regulation of cellular amine metabolic processGO:003324000.021
cofactor metabolic processGO:0051186150.021
response to ethanolGO:004547160.021
establishment of protein localization to organelleGO:007259440.021
gamete generationGO:0007276330.021
ubiquitin dependent protein catabolic processGO:000651130.021
cellular component morphogenesisGO:00329893360.021
response to bacteriumGO:0009617580.020
cellular nitrogen compound metabolic processGO:00346412900.020
response to glucoseGO:000974930.020
cellular component movementGO:00069283350.020
negative regulation of apoptotic processGO:0043066550.020
carboxylic acid catabolic processGO:004639530.020
positive regulation of inflammatory responseGO:005072910.020
small molecule catabolic processGO:004428230.020
regulation of protein import into nucleusGO:004230620.020
modification dependent macromolecule catabolic processGO:004363230.019
growthGO:00400071740.019
removal of superoxide radicalsGO:001943020.019
gtp metabolic processGO:004603940.019
regulation of reactive oxygen species metabolic processGO:200037720.019
cytoskeleton dependent cytokinesisGO:006164030.019
neuron developmentGO:00486662620.019
response to molecule of bacterial originGO:0002237140.019
positive regulation of nucleoside metabolic processGO:004597910.019
cell substrate junction assemblyGO:000704420.019
cellular macromolecule catabolic processGO:0044265120.019
meiotic nuclear divisionGO:000712640.019
regulation of cellular ketone metabolic processGO:001056570.019
regulation of cell differentiationGO:00455951420.019
cellular amide metabolic processGO:004360340.019
guanosine containing compound catabolic processGO:190106920.019
nucleobase containing compound metabolic processGO:00061392740.019
cellular response to external stimulusGO:007149620.018
regulation of cellular metabolic processGO:00313233200.018
regulation of cellular protein catabolic processGO:190336210.018
regulation of primary metabolic processGO:00800903110.018
nucleocytoplasmic transportGO:000691340.018
negative regulation of programmed cell deathGO:0043069580.018
enzyme linked receptor protein signaling pathwayGO:00071671060.018
response to carbohydrateGO:000974330.018
positive regulation of striated muscle cell differentiationGO:005115510.018
single organism catabolic processGO:0044712130.018
positive regulation of proteolysisGO:0045862100.018
response to hexoseGO:000974630.018
gastrulation with mouth forming secondGO:0001702440.018
regulation of hormone secretionGO:004688320.018
regulation of transporter activityGO:003240920.018
regulation of localizationGO:00328791040.017
porphyrin containing compound metabolic processGO:0006778100.017
reactive oxygen species biosynthetic processGO:190340910.017
positive regulation of cell communicationGO:0010647560.017
taxisGO:00423301090.017
striated muscle tissue developmentGO:00147061100.017
regulation of intracellular protein transportGO:003315730.017
tissue regenerationGO:0042246740.017
negative regulation of response to stimulusGO:00485851040.017
synaptic vesicle transportGO:004848910.017
regulation of nucleoside metabolic processGO:000911820.017
peptide transportGO:001583310.017
fatty acid elongationGO:003049710.017
response to stressGO:00069502630.017
single organism carbohydrate metabolic processGO:0044723120.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
cell projection morphogenesisGO:00488582440.017
neuroblast proliferationGO:000740520.016
positive regulation of cytokine productionGO:000181920.016
peptide metabolic processGO:000651810.016
nucleobase containing compound transportGO:001593120.016
muscle structure developmentGO:00610611960.016
regulation of transmembrane transporter activityGO:002289820.016
positive regulation of signal transductionGO:0009967560.016
cellular amino acid metabolic processGO:000652070.016
cellular response to molecule of bacterial originGO:007121930.016
regulation of muscle contractionGO:000693730.016
positive regulation of secretion by cellGO:190353210.016
cellular catabolic processGO:0044248270.016
positive regulation of response to stimulusGO:0048584800.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
regulation of peptidase activityGO:0052547230.016
regulation of ion transmembrane transporter activityGO:003241220.016
regulation of production of molecular mediator of immune responseGO:000270010.016
regulation of signal transductionGO:00099662250.016
localization of cellGO:00516742440.016
gene expressionGO:00104672520.016
positive regulation of gtp catabolic processGO:003312610.015
monoamine transportGO:001584410.015
transmembrane transportGO:00550851200.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
response to phGO:000926820.015
positive regulation of cellular processGO:00485222010.015
response to lipidGO:0033993600.015
regulation of protein transportGO:005122330.015
response to other organismGO:0051707970.015
cell morphogenesis involved in differentiationGO:00009041950.015
meiotic chromosome segregationGO:004513230.015
cellular modified amino acid metabolic processGO:000657530.015
regulation of cell motilityGO:2000145460.015
positive regulation of cell activationGO:005086710.015
rna transportGO:005065820.015
organelle organizationGO:00069962270.014
biosynthetic processGO:00090582940.014
innate immune responseGO:0045087130.014
response to abiotic stimulusGO:00096281220.014
cell migrationGO:00164772370.014
response to unfolded proteinGO:000698620.014
immune responseGO:0006955280.014
response to vitaminGO:003327330.014
i kappab kinase nf kappab signalingGO:000724940.014
neurotransmitter transportGO:000683620.014
organelle assemblyGO:00709251100.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
regulation of endopeptidase activityGO:0052548230.014
response to inorganic substanceGO:0010035380.014
regulation of reproductive processGO:200024140.014
immune effector processGO:0002252230.014
cellular component maintenanceGO:004395430.014
cellular response to nutrient levelsGO:003166920.013
regulation of purine nucleotide catabolic processGO:003312120.013
positive regulation of cell deathGO:0010942290.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
protein acylationGO:004354330.013
adherens junction organizationGO:003433240.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
negative regulation of cell communicationGO:0010648960.013
membrane hyperpolarizationGO:006008110.013
response to corticosteroidGO:003196010.013
regulation of protein targetingGO:190353320.013
regulation of neurotransmitter transportGO:005158810.013
positive regulation of signalingGO:0023056560.013
cellular response to extracellular stimulusGO:003166820.013
positive regulation of secretionGO:005104710.013
amino acid transportGO:000686520.013
cell part morphogenesisGO:00329902460.013
lymphocyte proliferationGO:004665110.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
regulation of cellular component organizationGO:0051128860.013
establishment of rna localizationGO:005123630.013
hormone transportGO:000991420.013
meiotic cell cycle processGO:190304630.013
cellular response to reactive oxygen speciesGO:003461420.013
single organism membrane organizationGO:0044802200.013
internal protein amino acid acetylationGO:000647520.013
single organism reproductive processGO:0044702400.013
wound healingGO:0042060900.012
cleavage furrow formationGO:003608920.012
regulation of sodium ion transportGO:000202820.012
cytokinetic processGO:003250620.012
cellular localizationGO:0051641970.012
myeloid leukocyte migrationGO:0097529120.012
response to axon injuryGO:0048678140.012
protein targeting to vacuoleGO:000662310.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
cellular response to superoxideGO:007145120.012
ribonucleoside monophosphate catabolic processGO:000915840.012
post golgi vesicle mediated transportGO:000689210.012
atp catabolic processGO:000620040.012
ion homeostasisGO:0050801410.012
regenerationGO:0031099910.012
adult behaviorGO:003053420.012
hemoglobin biosynthetic processGO:004254180.012
cation transportGO:0006812810.012
protein localization to vacuoleGO:007266510.012
nitrogen compound transportGO:0071705230.012
regulation of carbohydrate biosynthetic processGO:004325510.012
peptidyl serine modificationGO:001820920.012
activation of mapk activityGO:000018730.012
calcium ion transport into cytosolGO:006040230.011
cellular extravasationGO:004512310.011
positive regulation of wound healingGO:009030310.011
cytokinesisGO:000091030.011
regulation of multicellular organismal developmentGO:20000262230.011
phagocytosisGO:000690930.011
defense response to fungusGO:005083220.011
regulation of gene expressionGO:00104682650.011
golgi vesicle transportGO:004819330.011
reproductive processGO:0022414400.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.011
cellular aromatic compound metabolic processGO:00067252950.011
cell proliferationGO:0008283800.011
regulation of cysteine type endopeptidase activityGO:2000116210.011
astrocyte differentiationGO:004870810.011
cellular response to organic substanceGO:00713101050.011
synaptic vesicle localizationGO:009747910.011
cellular biosynthetic processGO:00442492860.011
positive regulation of cellular extravasationGO:000269310.011
neuron projection morphogenesisGO:00488121610.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of molecular functionGO:0044093330.011
regulation of anatomical structure sizeGO:0090066330.011
regulation of lipid catabolic processGO:005099420.011
regulation of neurotransmitter secretionGO:004692810.011
compound eye developmentGO:004874920.011
negative regulation of multi organism processGO:004390130.010
regulation of locomotionGO:0040012550.010
regulation of protein localization to plasma membraneGO:190307610.010
cellular ketone metabolic processGO:0042180110.010
regulation of membrane potentialGO:0042391230.010
carbohydrate homeostasisGO:003350010.010
organic acid catabolic processGO:001605430.010
embryonic heart tube developmentGO:00350501330.010
response to organic cyclic compoundGO:0014070510.010
carbohydrate derivative metabolic processGO:1901135610.010
muscle tissue developmentGO:00605371100.010
heterocycle metabolic processGO:00464832900.010
regulation of cellular component movementGO:0051270550.010
ovulation cycleGO:004269820.010
regulation of calcium ion transportGO:005192420.010
homeostatic processGO:00425921420.010
protein localization to nucleusGO:003450430.010
metal ion transportGO:0030001580.010
regulation of cellular amine metabolic processGO:003323800.010
multicellular organismal homeostasisGO:0048871290.010
reproductionGO:0000003400.010
negative regulation of chemotaxisGO:005092240.010
negative regulation of signal transductionGO:0009968940.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
fatty acid beta oxidationGO:000663510.010
homeostasis of number of cells within a tissueGO:004887340.010
negative regulation of reproductive processGO:200024230.010
regulation of circadian sleep wake cycle sleepGO:004518710.010
regulation of wound healingGO:006104120.010

ctsz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.112
inherited metabolic disorderDOID:65500.112
disease of anatomical entityDOID:700.077
nervous system diseaseDOID:86300.053
immune system diseaseDOID:291400.021
acquired metabolic diseaseDOID:006015800.012
amyloidosisDOID:912000.012
hematopoietic system diseaseDOID:7400.010