Danio rerio

12 known processes

LOC100006043

Kruppel-like factor 5-like

LOC100006043 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein localization to nucleusGO:190018020.108
larval developmentGO:000216420.104
response to drugGO:004249330.099
agingGO:000756820.098
regulation of protein import into nucleusGO:004230620.096
cell surface receptor signaling pathwayGO:00071663250.093
cellular component movementGO:00069283350.089
response to chemicalGO:00422213200.089
localization of cellGO:00516742440.087
regulation of establishment of protein localizationGO:007020140.086
nucleocytoplasmic transportGO:000691340.085
positive regulation of cellular component biogenesisGO:004408930.084
ameboidal type cell migrationGO:00016671430.082
response to external stimulusGO:00096052640.081
regulation of nucleobase containing compound metabolic processGO:00192192500.080
cell motilityGO:00488702440.078
positive regulation of biological processGO:00485182530.078
regulation of cellular metabolic processGO:00313233200.078
cell projection organizationGO:00300302840.077
regulation of multicellular organismal processGO:00512392770.076
protein importGO:001703830.074
regulation of protein targetingGO:190353320.074
gene expressionGO:00104672520.073
protein targeting to nucleusGO:004474430.073
single organism nuclear importGO:190259330.071
cell part morphogenesisGO:00329902460.070
sensory organ developmentGO:00074233930.069
muscle cell differentiationGO:00426921390.068
protein localization to nucleusGO:003450430.068
regulation of primary metabolic processGO:00800903110.066
multicellular organism growthGO:003526440.064
cellular aromatic compound metabolic processGO:00067252950.064
establishment of protein localization to organelleGO:007259440.064
protein import into nucleusGO:000660630.064
cellular response to external stimulusGO:007149620.062
organic substance biosynthetic processGO:19015762890.062
eye developmentGO:00016542770.061
nuclear transportGO:005116940.061
regulation of macromolecule metabolic processGO:00602553170.060
regulation of biosynthetic processGO:00098892500.060
nuclear importGO:005117030.059
regulation of protein polymerizationGO:003227120.057
regulation of protein transportGO:005122330.057
regulation of nucleocytoplasmic transportGO:004682220.056
positive regulation of protein complex assemblyGO:003133420.056
actin polymerization or depolymerizationGO:000815420.056
regulation of protein complex assemblyGO:004325430.056
protein polymerizationGO:005125840.055
cell migrationGO:00164772370.055
response to organic substanceGO:00100331530.054
signal transductionGO:00071654550.054
guanosine containing compound metabolic processGO:190106840.054
head developmentGO:00603223030.054
regulation of intracellular protein transportGO:003315730.052
apoptotic processGO:00069151160.052
generation of neuronsGO:00486993850.052
regulation of gene expressionGO:00104682650.051
regulation of nucleotide catabolic processGO:003081120.051
regulation of rna biosynthetic processGO:20011412130.051
cellular response to extracellular stimulusGO:003166820.050
positive regulation of transportGO:005105020.049
cellular response to chemical stimulusGO:00708871570.049
regulation of apoptotic processGO:0042981980.049
gtp metabolic processGO:004603940.049
cellular component morphogenesisGO:00329893360.048
cellular response to nutrient levelsGO:003166920.048
digestive tract developmentGO:00485652650.047
positive regulation of cellular amino acid metabolic processGO:004576400.047
morphogenesis of an epitheliumGO:00020093330.046
heterocycle metabolic processGO:00464832900.046
peptidyl serine modificationGO:001820920.046
response to nutrientGO:000758430.046
regulation of cytoplasmic transportGO:190364940.045
nucleobase containing compound biosynthetic processGO:00346542050.045
regulation of cellular biosynthetic processGO:00313262450.045
nitrogen compound metabolic processGO:00068073190.044
amine metabolic processGO:000930820.044
guanosine containing compound catabolic processGO:190106920.044
sensory organ morphogenesisGO:00905962000.044
macroautophagyGO:001623610.043
regulation of response to stimulusGO:00485832690.043
phagocytosisGO:000690930.042
camera type eye developmentGO:00430102220.042
striated muscle cell differentiationGO:00511461290.041
positive regulation of protein polymerizationGO:003227320.041
regulation of wound healingGO:006104120.041
regulation of cell deathGO:00109411030.040
muscle structure developmentGO:00610611960.040
organic cyclic compound biosynthetic processGO:19013622230.040
cell morphogenesisGO:00009022890.040
cellular biosynthetic processGO:00442492860.040
cellular nitrogen compound metabolic processGO:00346412900.040
response to biotic stimulusGO:0009607970.040
response to stressGO:00069502630.039
regulation of cell shapeGO:000836010.039
cellular response to oxygen levelsGO:007145310.039
positive regulation of cellular catabolic processGO:003133130.038
heart morphogenesisGO:00030071560.038
regulation of protein catabolic processGO:004217610.038
regulation of programmed cell deathGO:00430671010.038
positive regulation of catabolic processGO:000989640.038
regulation of macromolecule biosynthetic processGO:00105562250.037
negative regulation of cellular catabolic processGO:003133030.037
cellular response to starvationGO:000926710.037
regulation of cell communicationGO:00106462320.037
chordate embryonic developmentGO:00430092710.037
maintenance of locationGO:005123540.036
regulation of cellular ketone metabolic processGO:001056570.036
cellular ketone metabolic processGO:0042180110.036
regulation of cellular amine metabolic processGO:003323800.036
regulation of metabolic processGO:00192223590.036
negative regulation of cellular processGO:00485232830.036
embryonic organ morphogenesisGO:00485622740.035
regulation of nucleoside metabolic processGO:000911820.035
central nervous system developmentGO:00074173870.035
regulation of biological qualityGO:00650082630.034
negative regulation of cytoplasmic transportGO:190365020.034
actin filament polymerizationGO:003004120.034
regulation of cellular amino acid metabolic processGO:000652100.034
cell projection morphogenesisGO:00488582440.034
organic cyclic compound metabolic processGO:19013603010.033
nucleobase containing compound metabolic processGO:00061392740.033
cellular amino acid metabolic processGO:000652070.033
cellular macromolecule metabolic processGO:00442603910.032
cellular component disassemblyGO:002241110.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
regulation of gtp catabolic processGO:003312420.032
locomotionGO:00400113130.032
embryonic organ developmentGO:00485683810.032
small molecule metabolic processGO:0044281770.032
system processGO:00030081850.032
regulation of purine nucleotide catabolic processGO:003312120.032
gtp catabolic processGO:000618420.031
regionalizationGO:00030022740.031
positive regulation of nitrogen compound metabolic processGO:0051173690.031
regulation of nitrogen compound metabolic processGO:00511712510.031
cellular protein metabolic processGO:00442671290.031
regulation of autophagyGO:001050630.031
negative regulation of biological processGO:00485193040.031
negative regulation of protein localization to nucleusGO:190018120.031
protein metabolic processGO:00195381830.031
positive regulation of metabolic processGO:00098931080.031
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
cellular macromolecule biosynthetic processGO:00346452240.030
macromolecule biosynthetic processGO:00090592270.030
extrinsic apoptotic signaling pathwayGO:009719130.030
regulation of reactive oxygen species metabolic processGO:200037720.030
negative regulation of protein transportGO:005122430.029
heart developmentGO:00075073130.029
positive regulation of cytoskeleton organizationGO:005149530.029
cell deathGO:00082191210.029
organic acid metabolic processGO:0006082310.029
biosynthetic processGO:00090582940.029
nucleic acid templated transcriptionGO:00976591810.029
autophagyGO:000691440.029
cell morphogenesis involved in differentiationGO:00009041950.029
stem cell proliferationGO:007208940.029
response to external biotic stimulusGO:0043207970.029
transcription from rna polymerase ii promoterGO:0006366800.029
programmed cell deathGO:00125011190.028
positive regulation of cell cycleGO:004578730.028
eye morphogenesisGO:00485921440.028
lamellipodium organizationGO:009758110.028
regulation of developmental processGO:00507932470.028
response to other organismGO:0051707970.028
astrocyte differentiationGO:004870810.028
brain developmentGO:00074202930.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
modification dependent protein catabolic processGO:001994130.027
oxoacid metabolic processGO:0043436310.027
regulation of myotube differentiationGO:001083020.027
transcription dna templatedGO:00063511810.027
regulation of multicellular organism growthGO:004001440.026
synaptic growth at neuromuscular junctionGO:005112420.026
modification dependent macromolecule catabolic processGO:004363230.026
lamellipodium assemblyGO:003003210.026
regulation of multicellular organismal developmentGO:20000262230.025
mesenchyme developmentGO:00604851270.025
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.025
tube morphogenesisGO:00352393490.025
single organism localizationGO:19025782250.025
homeostatic processGO:00425921420.025
positive regulation of epithelial cell migrationGO:001063420.024
regulation of anatomical structure morphogenesisGO:00226031300.024
stem cell divisionGO:001714510.024
urogenital system developmentGO:0001655970.024
regulation of cysteine type endopeptidase activityGO:2000116210.024
regulation of transcription dna templatedGO:00063552130.024
negative regulation of metabolic processGO:0009892860.024
cellular protein catabolic processGO:004425740.024
carboxylic acid metabolic processGO:0019752220.024
mesenchymal cell developmentGO:0014031780.024
myeloid cell differentiationGO:0030099860.024
regulation of bindingGO:005109830.024
positive regulation of muscle cell differentiationGO:005114910.023
regulation of response to nutrient levelsGO:003210710.023
pigmentationGO:0043473850.023
epithelial cell differentiationGO:00308551160.023
embryonic heart tube developmentGO:00350501330.023
regulation of cell projection assemblyGO:006049140.023
regulation of gtpase activityGO:004308720.023
regulation of cytokine productionGO:000181730.023
establishment of localizationGO:00512342440.023
developmental growthGO:00485891660.023
proteasomal protein catabolic processGO:001049820.022
growthGO:00400071740.022
cellular response to organic substanceGO:00713101050.022
regulation of molecular functionGO:0065009700.022
actin mediated cell contractionGO:007025210.022
negative regulation of gene expressionGO:0010629650.022
cell projection assemblyGO:0030031640.022
rna metabolic processGO:00160702190.022
regulation of blood vessel sizeGO:005088020.022
neuron differentiationGO:00301823530.022
endosomal transportGO:001619720.022
gastrulationGO:00073692080.022
regulation of response to stressGO:0080134360.022
response to light stimulusGO:0009416460.022
epithelial tube morphogenesisGO:00605621480.022
negative regulation of nucleocytoplasmic transportGO:004682320.022
cellular response to endogenous stimulusGO:0071495680.022
negative regulation of response to stimulusGO:00485851040.022
ubiquitin dependent protein catabolic processGO:000651130.021
regulation of endopeptidase activityGO:0052548230.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
gland developmentGO:00487321430.021
negative regulation of cell communicationGO:0010648960.021
somite developmentGO:0061053960.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
aromatic compound biosynthetic processGO:00194382170.021
rna biosynthetic processGO:00327741810.021
regulation of rna metabolic processGO:00512522240.020
sleepGO:003043110.020
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.020
somatic muscle developmentGO:000752540.020
muscle tissue developmentGO:00605371100.020
somitogenesisGO:0001756870.020
organonitrogen compound metabolic processGO:1901564740.020
cellular amine metabolic processGO:004410620.020
cellular response to hypoxiaGO:007145610.020
blood vessel developmentGO:00015682460.020
positive regulation of cytokine productionGO:000181920.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.020
negative regulation of catabolic processGO:000989530.020
response to endogenous stimulusGO:0009719830.020
regulation of mrna processingGO:005068430.020
negative regulation of signalingGO:0023057960.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
stem cell maintenanceGO:001982740.020
membrane fusionGO:006102520.020
positive regulation of macromolecule metabolic processGO:0010604930.020
cytokinesisGO:000091030.019
negative regulation of intracellular transportGO:003238730.019
lateral line system developmentGO:0048925760.019
positive regulation of cellular biosynthetic processGO:0031328680.019
regulation of localizationGO:00328791040.019
hemopoiesisGO:00300971830.019
anterior posterior pattern specificationGO:00099521520.019
negative regulation of intracellular protein transportGO:009031730.019
macromolecular complex disassemblyGO:003298410.019
vasculature developmentGO:00019442780.019
skeletal system developmentGO:00015011810.019
heterocycle biosynthetic processGO:00181302150.019
hepaticobiliary system developmentGO:0061008980.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
inner ear developmentGO:00488391260.019
neuronal action potentialGO:0019228180.019
ear developmentGO:00435831270.018
developmental programmed cell deathGO:001062340.018
leukocyte proliferationGO:007066110.018
fertilizationGO:000956630.018
female sex differentiationGO:004666040.018
spermatid developmentGO:000728620.018
digestive system developmentGO:00551232890.018
positive regulation of cellular metabolic processGO:0031325940.018
zymogen activationGO:003163830.018
retina development in camera type eyeGO:00600411460.018
convergent extension involved in gastrulationGO:0060027710.018
digestive tract morphogenesisGO:00485462310.018
embryo development ending in birth or egg hatchingGO:00097922710.018
convergent extensionGO:00600261180.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
regulation of glial cell differentiationGO:004568540.018
positive regulation of cellular processGO:00485222010.018
peptidyl serine phosphorylationGO:001810510.018
regulation of protein metabolic processGO:0051246560.018
regulation of cellular protein metabolic processGO:0032268520.018
cellular response to growth factor stimulusGO:0071363390.017
wnt signaling pathwayGO:0016055800.017
negative regulation of protein phosphorylationGO:000193340.017
deathGO:00162651210.017
immune system developmentGO:00025201910.017
organic acid catabolic processGO:001605430.017
negative regulation of apoptotic processGO:0043066550.017
axon developmentGO:00615641660.017
response to woundingGO:00096111160.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
camera type eye morphogenesisGO:00485931080.017
regulation of epithelial cell proliferationGO:005067830.017
cellular response to decreased oxygen levelsGO:003629410.017
response to bacteriumGO:0009617580.017
negative regulation of macromolecule metabolic processGO:0010605760.017
phosphate containing compound metabolic processGO:00067961080.017
positive regulation of nucleoside metabolic processGO:004597910.017
negative regulation of cellular metabolic processGO:0031324770.017
striated muscle tissue developmentGO:00147061100.017
sensory system developmentGO:0048880760.017
intracellular signal transductionGO:0035556850.017
liver developmentGO:0001889960.017
regulation of locomotionGO:0040012550.017
muscle organ developmentGO:00075171010.017
peptidyl threonine phosphorylationGO:001810710.017
i kappab kinase nf kappab signalingGO:000724940.017
regulation of hydrolase activityGO:0051336280.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
regulation of tube sizeGO:003515020.016
lipid storageGO:001991510.016
regulation of cell differentiationGO:00455951420.016
adherens junction organizationGO:003433240.016
organelle fusionGO:004828430.016
regulation of signalingGO:00230512350.016
macromolecule modificationGO:00434121110.016
negative regulation of protein maturationGO:1903318100.016
negative regulation of protein complex assemblyGO:003133310.016
neuroblast proliferationGO:000740520.016
stem cell developmentGO:0048864820.016
proteolysisGO:0006508380.016
cell migration involved in gastrulationGO:0042074790.016
positive regulation of nucleotide catabolic processGO:003081310.016
spermatid differentiationGO:004851520.016
positive regulation of cellular amine metabolic processGO:003324000.016
transportGO:00068102200.016
response to vitaminGO:003327330.016
mitochondrion organizationGO:000700540.016
membrane invaginationGO:001032410.016
single organism metabolic processGO:00447102170.016
single organism membrane fusionGO:004480120.016
fin developmentGO:0033333770.016
embryonic skeletal system developmentGO:0048706970.016
wound healingGO:0042060900.016
protein complex localizationGO:003150310.016
response to carbohydrateGO:000974330.016
embryonic heart tube morphogenesisGO:00031431080.016
development of primary female sexual characteristicsGO:004654540.016
neural crest cell differentiationGO:0014033720.016
axonogenesisGO:00074091520.015
positive regulation of epithelial cell proliferationGO:005067910.015
regulation of protein bindingGO:004339330.015
post embryonic morphogenesisGO:000988640.015
xenobiotic metabolic processGO:000680540.015
regulation of rho protein signal transductionGO:003502320.015
regulation of cell activationGO:005086510.015
tissue migrationGO:0090130370.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
peptide transportGO:001583310.015
regulation of inflammatory responseGO:005072720.015
multi organism processGO:00517041340.015
atp catabolic processGO:000620040.015
positive regulation of biosynthetic processGO:0009891680.015
regulation of protein ubiquitinationGO:003139630.015
adult behaviorGO:003053420.015
angiogenesisGO:00015251580.015
positive regulation of blood circulationGO:190352420.015
neurological system processGO:0050877620.015
response to hexoseGO:000974630.015
regulation of ras gtpase activityGO:003231820.015
interspecies interaction between organismsGO:004441940.015
multi organism cellular processGO:004476420.015
cilium organizationGO:0044782710.015
phosphorylationGO:0016310690.014
neuron developmentGO:00486662620.014
protein modification processGO:00362111000.014
positive regulation of translationGO:004572710.014
blood vessel morphogenesisGO:00485142160.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
myotube differentiationGO:0014902450.014
multicellular organismal metabolic processGO:004423620.014
peptidyl threonine modificationGO:001821010.014
regulation of cellular component movementGO:0051270550.014
heart loopingGO:0001947940.014
apoptotic process involved in developmentGO:190274220.014
post embryonic organ developmentGO:004856940.014
response to corticosteroidGO:003196010.014
protein depolymerizationGO:005126110.014
regulation of synapse assemblyGO:005196330.014
regulation of synaptic plasticityGO:004816710.014
negative regulation of programmed cell deathGO:0043069580.014
secondary metabolic processGO:001974830.014
lipid catabolic processGO:001604240.014
b cell activationGO:004211320.014
renal system developmentGO:0072001940.014
response to glucocorticoidGO:005138410.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
phagocytosis engulfmentGO:000691110.014
stem cell differentiationGO:00488631170.014
rho protein signal transductionGO:000726650.014
regulation of multicellular organismal metabolic processGO:004424620.014
cognitionGO:005089010.014
regulation of reproductive processGO:200024140.014
transmission of nerve impulseGO:0019226190.014
mitotic dna integrity checkpointGO:004477440.013
compound eye developmentGO:004874920.013
regulation of cellular protein catabolic processGO:190336210.013
blood circulationGO:0008015870.013
positive regulation of macromolecule biosynthetic processGO:0010557590.013
production of molecular mediator of immune responseGO:000244020.013
connective tissue developmentGO:0061448990.013
female gonad developmentGO:000858540.013
nucleic acid metabolic processGO:00903042440.013
regulation of wnt signaling pathwayGO:0030111530.013
epidermal cell fate specificationGO:000995740.013
specification of symmetryGO:00097992040.013
defense response to other organismGO:0098542330.013
epithelial cell migrationGO:0010631250.013
protein processingGO:0016485120.013
dorsal ventral pattern formationGO:00099531250.013
reactive oxygen species metabolic processGO:007259360.013
regulation of stem cell differentiationGO:200073640.013
regulation of membrane potentialGO:0042391230.013
taxisGO:00423301090.013
response to growth factorGO:0070848390.013
melanocyte differentiationGO:0030318260.013
small gtpase mediated signal transductionGO:000726480.013
inner ear morphogenesisGO:0042472630.013
cilium morphogenesisGO:0060271850.013
centrosome organizationGO:005129710.013
cellular component assemblyGO:00226071700.013
cartilage developmentGO:0051216960.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
actin filament based movementGO:003004810.013
canonical wnt signaling pathwayGO:0060070480.013
lateral line developmentGO:0048882660.013
regulation of proteolysisGO:0030162240.013
ras protein signal transductionGO:000726570.013
defense responseGO:0006952470.013
positive regulation of gtpase activityGO:004354710.013
response to monosaccharideGO:003428430.012
cellular protein complex disassemblyGO:004362410.012
glial cell migrationGO:000834730.012
neuron projection developmentGO:00311751800.012
nuclear migrationGO:000709730.012
otic vesicle developmentGO:0071599420.012
regulation of rac protein signal transductionGO:003502010.012
regulation of metal ion transportGO:001095940.012
cell substrate adhesionGO:003158940.012
regulation of protein complex disassemblyGO:004324410.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
multicellular organismal signalingGO:0035637220.012
regulation of carbohydrate metabolic processGO:000610940.012
intracellular transportGO:0046907320.012
regulation of ion transmembrane transporter activityGO:003241220.012
action potentialGO:0001508190.012
response to glucoseGO:000974930.012
negative regulation of biosynthetic processGO:0009890550.012
positive regulation of cell activationGO:005086710.012
kidney developmentGO:0001822920.012
response to uvGO:000941130.012
skin developmentGO:0043588540.012
cellular localizationGO:0051641970.012
forebrain developmentGO:0030900960.012
determination of left right symmetryGO:00073681790.012
ribonucleoside monophosphate catabolic processGO:000915840.012
positive regulation of epithelial cell differentiationGO:003085820.012
regulation of cellular response to growth factor stimulusGO:0090287350.012
protein stabilizationGO:005082120.012
regulation of dna replicationGO:000627530.011
nucleoside monophosphate catabolic processGO:000912540.011
regulation of transmembrane transporter activityGO:002289820.011
positive regulation of gtp catabolic processGO:003312610.011
neural crest cell migrationGO:0001755420.011
carboxylic acid catabolic processGO:004639530.011
response to organic cyclic compoundGO:0014070510.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.011
protein secretionGO:000930610.011
regulation of cell migrationGO:0030334400.011
positive regulation of leukocyte differentiationGO:190210710.011
circulatory system processGO:0003013870.011
regulation of response to biotic stimulusGO:000283120.011
positive regulation of secretionGO:005104710.011
positive regulation of gene expressionGO:0010628710.011
cellular carbohydrate metabolic processGO:004426240.011
skeletal muscle organ developmentGO:0060538780.011
regulation of signal transductionGO:00099662250.011

LOC100006043 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.063
cancerDOID:16200.018
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
nervous system diseaseDOID:86300.018
musculoskeletal system diseaseDOID:1700.017
cardiovascular system diseaseDOID:128700.013
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012