Danio rerio

0 known processes

dspa

desmoplakin a

(Aliases: im:6911953,wu:fk73d01,sb:cb570,wu:fc17a08)

dspa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
desmosome organizationGO:000293430.786
Mouse
desmosome assemblyGO:000215920.365
regulation of striated muscle contractionGO:000694220.277
Human
polarized epithelial cell differentiationGO:003085940.192
cellular component movementGO:00069283350.191
cellular component morphogenesisGO:00329893360.183
adherens junction organizationGO:003433240.182
Mouse
convergent extensionGO:00600261180.176
localization of cellGO:00516742440.157
cellular component biogenesisGO:00440851780.147
gene expressionGO:00104672520.146
cell morphogenesis involved in differentiationGO:00009041950.144
regulation of stem cell differentiationGO:200073640.144
regulation of cell developmentGO:00602841000.140
establishment of epithelial cell polarityGO:009016220.140
digestive tract developmentGO:00485652650.133
regulation of muscle contractionGO:000693730.129
Human
cell motilityGO:00488702440.129
cell cell junction organizationGO:0045216100.127
Mouse
morphogenesis of an epitheliumGO:00020093330.125
extrinsic apoptotic signaling pathwayGO:009719130.123
locomotionGO:00400113130.122
cell migrationGO:00164772370.120
morphogenesis of an epithelial sheetGO:0002011490.114
actin mediated cell contractionGO:007025210.106
establishment of epithelial cell apical basal polarityGO:004519820.103
regulation of biological qualityGO:00650082630.100
Human
regulation of actin filament based movementGO:190311510.099
Human
establishment of protein localization to plasma membraneGO:009000210.091
regulation of anatomical structure morphogenesisGO:00226031300.090
kidney developmentGO:0001822920.084
cardiac conductionGO:006133730.080
Human
cognitionGO:005089010.078
epibolyGO:0090504410.077
tube morphogenesisGO:00352393490.077
response to external stimulusGO:00096052640.076
gastrulationGO:00073692080.075
organelle organizationGO:00069962270.075
Mouse
regulation of response to stimulusGO:00485832690.074
regulation of macromolecule metabolic processGO:00602553170.074
cartilage condensationGO:000150230.073
vasculature developmentGO:00019442780.070
regulation of synaptic plasticityGO:004816710.070
hematopoietic or lymphoid organ developmentGO:00485341910.069
actin filament based processGO:0030029640.069
neuron differentiationGO:00301823530.069
camera type eye developmentGO:00430102220.069
actin cytoskeleton organizationGO:0030036630.067
regulation of cell morphogenesis involved in differentiationGO:0010769380.066
epidermal cell differentiationGO:0009913360.065
Human
positive regulation of transportGO:005105020.065
digestive tract morphogenesisGO:00485462310.065
cellular response to extracellular stimulusGO:003166820.064
pronephros developmentGO:0048793690.062
regulation of gene expressionGO:00104682650.062
neuron projection developmentGO:00311751800.062
regulation of membrane potentialGO:0042391230.062
Human
ectoderm developmentGO:000739890.060
cell junction organizationGO:0034330110.060
Mouse
growthGO:00400071740.060
regulation of metabolic processGO:00192223590.059
neuroblast differentiationGO:001401610.059
epithelial cell differentiationGO:00308551160.059
Human
ectodermal cell fate specificationGO:000171520.057
positive regulation of cellular component biogenesisGO:004408930.055
axis elongation involved in somitogenesisGO:009024520.053
single organism localizationGO:19025782250.053
single fertilizationGO:000733830.052
generation of neuronsGO:00486993850.052
neural crest cell migrationGO:0001755420.051
immune system processGO:00023762410.050
eye developmentGO:00016542770.050
cell morphogenesisGO:00009022890.049
female sex differentiationGO:004666040.049
cytoskeleton organizationGO:0007010960.049
Mouse
regulation of heart rateGO:000202750.049
Human
system processGO:00030081850.048
Human
digestive system developmentGO:00551232890.047
regulation of nucleobase containing compound metabolic processGO:00192192500.047
regulation of water loss via skinGO:003356110.046
regulation of organ morphogenesisGO:2000027350.046
regulation of multicellular organismal developmentGO:20000262230.046
negative regulation of epithelial cell proliferationGO:005068010.046
dorsal convergenceGO:0060030140.045
skin developmentGO:0043588540.045
Human Mouse
agingGO:000756820.045
blood vessel morphogenesisGO:00485142160.044
multi organism processGO:00517041340.043
regulation of developmental processGO:00507932470.043
negative regulation of stem cell differentiationGO:200073720.043
sensory organ developmentGO:00074233930.043
regulation of cell differentiationGO:00455951420.043
regulation of establishment of protein localizationGO:007020140.043
cell projection organizationGO:00300302840.042
negative regulation of cell fate specificationGO:0009996110.042
axon developmentGO:00615641660.042
renal system developmentGO:0072001940.042
cellular component assemblyGO:00226071700.041
cell cell adhesion involved in mesendodermal cell migrationGO:000337010.040
heart developmentGO:00075073130.040
Mouse
establishment of monopolar cell polarityGO:006116220.040
hemopoiesisGO:00300971830.040
blood circulationGO:0008015870.040
Human
epithelial tube morphogenesisGO:00605621480.039
negative regulation of cellular processGO:00485232830.039
odontogenesis of dentin containing toothGO:004247510.039
protein localization to plasma membraneGO:007265910.039
cell cell adhesion involved in gastrulationGO:007058640.039
stem cell differentiationGO:00488631170.039
somite developmentGO:0061053960.038
negative regulation of response to stimulusGO:00485851040.038
angiogenesisGO:00015251580.038
multicellular organismal signalingGO:0035637220.038
Human
embryonic organ developmentGO:00485683810.037
regulation of eye photoreceptor cell developmentGO:004247820.037
fertilizationGO:000956630.037
tissue migrationGO:0090130370.036
mesenchyme developmentGO:00604851270.036
gastrulation with mouth forming secondGO:0001702440.035
larval developmentGO:000216420.035
cell aggregationGO:009874330.035
blood vessel developmentGO:00015682460.035
regulation of epithelial cell proliferationGO:005067830.035
developmental growth involved in morphogenesisGO:0060560860.035
protein stabilizationGO:005082120.035
cell projection morphogenesisGO:00488582440.035
phagocytosisGO:000690930.034
cellular aromatic compound metabolic processGO:00067252950.034
regulation of protein complex assemblyGO:004325430.034
regulation of protein transportGO:005122330.033
ameboidal type cell migrationGO:00016671430.033
cellular response to nutrient levelsGO:003166920.033
nitrogen compound metabolic processGO:00068073190.033
secondary metabolic processGO:001974830.033
retina development in camera type eyeGO:00600411460.033
camera type eye morphogenesisGO:00485931080.033
regulation of neuron differentiationGO:0045664560.033
keratinocyte differentiationGO:003021600.033
Human
inner ear receptor cell differentiationGO:0060113290.033
phagocytosis engulfmentGO:000691110.032
neuron projection morphogenesisGO:00488121610.032
protein importGO:001703830.032
epidermis developmentGO:0008544480.032
Human
synaptic growth at neuromuscular junctionGO:005112420.032
amine metabolic processGO:000930820.031
cellular response to starvationGO:000926710.031
mesendoderm developmentGO:0048382100.031
cellular component maintenanceGO:004395430.031
axonogenesisGO:00074091520.031
cell junction maintenanceGO:003433120.031
regulation of protein polymerizationGO:003227120.031
sarcomere organizationGO:0045214260.031
regulation of signal transductionGO:00099662250.031
positive regulation of catabolic processGO:000989640.031
segmentationGO:0035282970.030
determination of bilateral symmetryGO:00098552040.030
stem cell developmentGO:0048864820.030
cellular macromolecule metabolic processGO:00442603910.030
Human
positive regulation of biological processGO:00485182530.030
single organism organelle organizationGO:19025891990.030
Mouse
convergent extension involved in gastrulationGO:0060027710.030
regulation of multicellular organismal processGO:00512392770.029
Human
mesenchymal cell developmentGO:0014031780.029
regulation of signalingGO:00230512350.029
embryo development ending in birth or egg hatchingGO:00097922710.029
regulation of embryonic developmentGO:0045995470.029
cellular macromolecule biosynthetic processGO:00346452240.029
long chain fatty acid metabolic processGO:000167610.028
reproductive processGO:0022414400.028
endoderm developmentGO:0007492490.028
hair cell differentiationGO:0035315320.028
epiboly involved in gastrulation with mouth forming secondGO:0055113350.027
regulation of epithelial to mesenchymal transitionGO:001071730.027
establishment of localizationGO:00512342440.027
complement activationGO:000695630.027
inner ear receptor cell developmentGO:0060119200.027
signal transductionGO:00071654550.027
guanosine containing compound metabolic processGO:190106840.027
meiotic nuclear divisionGO:000712640.027
urogenital system developmentGO:0001655970.026
adherens junction maintenanceGO:003433420.026
regulation of primary metabolic processGO:00800903110.026
response to topologically incorrect proteinGO:003596620.026
nucleobase containing compound metabolic processGO:00061392740.026
positive regulation of molecular functionGO:0044093330.026
regulation of cell activationGO:005086510.026
cardiac cell fate commitmentGO:006091110.025
heart valve formationGO:000318840.025
regulation of ectodermal cell fate specificationGO:004266520.025
positive regulation of epithelial cell migrationGO:001063420.025
regulation of actin cytoskeleton organizationGO:003295680.025
mesenchymal cell differentiationGO:0048762870.025
epithelium migrationGO:0090132250.025
regulation of cell morphogenesisGO:0022604420.025
response to chemicalGO:00422213200.025
protein heterooligomerizationGO:005129110.025
cortical actin cytoskeleton organizationGO:003086610.025
regulation of neurogenesisGO:0050767870.024
stem cell maintenanceGO:001982740.024
regulation of wound healingGO:006104120.024
stem cell proliferationGO:007208940.024
regulation of synapse assemblyGO:005196330.024
immune system developmentGO:00025201910.024
cellular response to external stimulusGO:007149620.024
brain developmentGO:00074202930.024
neuron developmentGO:00486662620.023
protein metabolic processGO:00195381830.023
Human
regionalizationGO:00030022740.023
actomyosin structure organizationGO:0031032530.023
regulation of cellular component sizeGO:0032535300.023
programmed cell deathGO:00125011190.023
negative regulation of biological processGO:00485193040.023
positive regulation of developmental processGO:0051094500.023
specification of symmetryGO:00097992040.023
regulation of cellular component organizationGO:0051128860.023
cell migration involved in gastrulationGO:0042074790.023
neural crest cell developmentGO:0014032620.023
cellular biosynthetic processGO:00442492860.023
response to biotic stimulusGO:0009607970.022
axial mesoderm developmentGO:0048318100.022
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.022
optic nerve developmentGO:0021554150.022
transportGO:00068102200.022
positive regulation of protein complex assemblyGO:003133420.022
regulation of cellular amine metabolic processGO:003323800.021
hindbrain developmentGO:0030902910.021
stem cell fate commitmentGO:004886510.021
muscle cell developmentGO:00550011150.021
protein polymerizationGO:005125840.021
regulation of locomotionGO:0040012550.021
regulation of cell matrix adhesionGO:000195210.020
response to stressGO:00069502630.020
lipid catabolic processGO:001604240.020
cortical cytoskeleton organizationGO:003086510.020
cellular nitrogen compound metabolic processGO:00346412900.020
regulation of nervous system developmentGO:0051960900.020
determination of left right symmetryGO:00073681790.020
muscle contractionGO:0006936180.020
gtp metabolic processGO:004603940.020
regulation of apoptotic processGO:0042981980.020
odontogenesisGO:004247690.020
heterocycle metabolic processGO:00464832900.020
lipid storageGO:001991510.020
ectoderm formationGO:000170520.020
inner ear receptor stereocilium organizationGO:006012280.020
regulation of localizationGO:00328791040.020
Human
nucleobase containing compound biosynthetic processGO:00346542050.020
regulation of erk1 and erk2 cascadeGO:007037240.020
response to drugGO:004249330.020
biosynthetic processGO:00090582940.020
sensory perception of painGO:001923310.019
single organism transportGO:00447652060.019
somatic stem cell maintenanceGO:003501910.019
apoptotic signaling pathwayGO:0097190230.019
membrane invaginationGO:001032410.019
phosphate containing compound metabolic processGO:00067961080.019
regulation of synapse organizationGO:005080730.019
regulation of axon extensionGO:0030516240.019
negative regulation of cell fate commitmentGO:0010454130.019
ion transportGO:00068111140.019
wnt signaling pathwayGO:0016055800.019
single organism metabolic processGO:00447102170.019
cell cell recognitionGO:000998810.019
regulation of metal ion transportGO:001095940.019
defense responseGO:0006952470.018
cellular amine metabolic processGO:004410620.018
multicellular organism growthGO:003526440.018
response to organic substanceGO:00100331530.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
positive regulation of cellular processGO:00485222010.018
anterior posterior pattern specificationGO:00099521520.018
establishment or maintenance of monopolar cell polarityGO:006133920.018
multicellular organismal water homeostasisGO:005089110.018
head developmentGO:00603223030.018
lateral line system developmentGO:0048925760.018
rna metabolic processGO:00160702190.018
circulatory system processGO:0003013870.018
Human
heterocycle biosynthetic processGO:00181302150.018
negative regulation of nuclear divisionGO:005178430.018
regulation of inflammatory responseGO:005072720.018
membrane raft organizationGO:003157910.017
fin developmentGO:0033333770.017
negative regulation of reproductive processGO:200024230.017
response to other organismGO:0051707970.017
tube formationGO:0035148250.017
smooth muscle contractionGO:000693920.017
mesoderm developmentGO:0007498880.017
negative regulation of mitosisGO:004583930.017
post anal tail morphogenesisGO:0036342190.017
medial fin developmentGO:0033338160.017
myeloid cell differentiationGO:0030099860.017
response to nutrientGO:000758430.017
endothelial cell migrationGO:0043542190.017
regulation of cell projection assemblyGO:006049140.017
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.017
semicircular canal developmentGO:0060872240.017
hepaticobiliary system developmentGO:0061008980.017
regulation of cellular amino acid metabolic processGO:000652100.017
inner ear developmentGO:00488391260.017
regulation of cell migrationGO:0030334400.017
regulation of transcription dna templatedGO:00063552130.016
regulation of cellular component movementGO:0051270550.016
Human
regulation of system processGO:0044057400.016
Human
mechanoreceptor differentiationGO:0042490370.016
nephron tubule morphogenesisGO:007207810.016
regulation of multicellular organism growthGO:004001440.016
negative regulation of cellular component organizationGO:0051129160.016
gtp catabolic processGO:000618420.016
nucleic acid metabolic processGO:00903042440.016
heart field specificationGO:000312810.016
membrane fusionGO:006102520.016
single organism cell adhesionGO:0098602290.016
Mouse
morphogenesis of an epithelial foldGO:006057110.016
cell substrate adhesionGO:003158940.016
negative regulation of rna splicingGO:003311910.015
macromolecule biosynthetic processGO:00090592270.015
centrosome organizationGO:005129710.015
muscle tissue developmentGO:00605371100.015
Mouse
eye morphogenesisGO:00485921440.015
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.015
blood vessel endothelial cell migrationGO:0043534180.015
maintenance of locationGO:005123540.015
neuroblast fate commitmentGO:001401710.015
lipid digestionGO:004424130.015
endoderm formationGO:0001706290.015
single organismal cell cell adhesionGO:0016337290.015
Mouse
water homeostasisGO:003010440.015
positive regulation of nucleoside metabolic processGO:004597910.014
cartilage developmentGO:0051216960.014
embryonic eye morphogenesisGO:0048048300.014
neural crest cell differentiationGO:0014033720.014
negative regulation of protein kinase b signalingGO:005189820.014
auditory receptor cell developmentGO:006011780.014
cell substrate junction assemblyGO:000704420.014
regulation of cell communicationGO:00106462320.014
endodermal cell fate specificationGO:0001714170.014
actin filament polymerizationGO:003004120.014
small gtpase mediated signal transductionGO:000726480.014
ras protein signal transductionGO:000726570.014
microtubule organizing center organizationGO:003102310.014
cell surface receptor signaling pathwayGO:00071663250.014
regulation of cardiac muscle cell contractionGO:008600410.014
Human
regulation of anatomical structure sizeGO:0090066330.014
organelle fusionGO:004828430.014
amino acid transportGO:000686520.014
spermatid differentiationGO:004851520.014
heart processGO:0003015710.014
Human
epithelial cell migrationGO:0010631250.014
establishment of apical basal cell polarityGO:003508920.014
erythrocyte homeostasisGO:0034101550.014
positive regulation of macromolecule metabolic processGO:0010604930.014
central nervous system developmentGO:00074173870.014
regulation of nucleotide catabolic processGO:003081120.014
regulation of cytokine productionGO:000181730.013
positive regulation of cytoskeleton organizationGO:005149530.013
protein import into nucleusGO:000660630.013
apoptotic processGO:00069151160.013
skeletal system morphogenesisGO:00487051020.013
regulation of response to external stimulusGO:0032101310.013
notochord developmentGO:0030903540.013
regulation of cellular metabolic processGO:00313233200.013
positive regulation of gtpase activityGO:004354710.013
regulation of ectoderm developmentGO:200038320.013
regulation of cell shapeGO:000836010.013
heart contractionGO:0060047710.013
Human
cardiocyte differentiationGO:0035051440.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
heart loopingGO:0001947940.013
sensory organ morphogenesisGO:00905962000.013
specification of axis polarityGO:006500140.013
actin polymerization or depolymerizationGO:000815420.013
regulation of sodium ion transportGO:000202820.013
cellular response to chemical stimulusGO:00708871570.013
catechol containing compound biosynthetic processGO:000971320.013
epithelial cell morphogenesisGO:000338220.013
mononuclear cell proliferationGO:003294310.013
establishment of endothelial barrierGO:006102830.013
deathGO:00162651210.012
tissue regenerationGO:0042246740.012
regulation of epidermis developmentGO:004568220.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
regenerationGO:0031099910.012
actin filament based movementGO:003004810.012
meiotic cell cycle processGO:190304630.012
lymphocyte proliferationGO:004665110.012
regulation of extent of cell growthGO:0061387290.012
formation of primary germ layerGO:0001704620.012
estrogen metabolic processGO:000821020.012
somitogenesisGO:0001756870.012
mesendoderm migrationGO:009013320.012
chordate embryonic developmentGO:00430092710.012
ectodermal cell fate commitmentGO:000171220.012
cellular component assembly involved in morphogenesisGO:00109271070.012
establishment or maintenance of bipolar cell polarityGO:0061245120.012
epidermis morphogenesisGO:004873040.012
regulation of cell fate commitmentGO:0010453220.012
cellular localizationGO:0051641970.012
nerve developmentGO:0021675450.012
microtubule based processGO:0007017600.012
ectodermal cell differentiationGO:001066820.012
auditory receptor cell morphogenesisGO:000209340.012
negative regulation of protein transportGO:005122430.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
organic cyclic compound metabolic processGO:19013603010.012
intracellular signal transductionGO:0035556850.012
osteoclast developmentGO:003603510.012
carboxylic acid metabolic processGO:0019752220.012
regulation of intracellular protein transportGO:003315730.011
regulation of cell deathGO:00109411030.011
response to alcoholGO:0097305140.011
oocyte anterior posterior axis specificationGO:000731440.011
negative regulation of kinase activityGO:003367340.011
erythrocyte differentiationGO:0030218540.011
positive regulation of cell cycleGO:004578730.011
response to woundingGO:00096111160.011
regulation of reproductive processGO:200024140.011
striated muscle tissue developmentGO:00147061100.011
Mouse
negative regulation of endothelial cell migrationGO:001059610.011
liver developmentGO:0001889960.011
negative regulation of blood vessel endothelial cell migrationGO:004353710.011
regulation of skeletal muscle tissue developmentGO:004864140.011
cell fate specificationGO:0001708680.011
regulation of mrna processingGO:005068430.011
regulation of cell motilityGO:2000145460.011
lipid metabolic processGO:0006629520.011
multicellular organismal metabolic processGO:004423620.011
sensory perceptionGO:0007600390.011
regulation of organelle organizationGO:0033043290.011
organelle assemblyGO:00709251100.011
cation transportGO:0006812810.011
developmental pigmentationGO:0048066480.011
organic substance biosynthetic processGO:19015762890.011
macromolecular complex assemblyGO:0065003350.011
carbohydrate derivative biosynthetic processGO:1901137430.011
regulation of response to stressGO:0080134360.011
guanosine containing compound catabolic processGO:190106920.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
positive regulation of cellular amine metabolic processGO:003324000.010
regulation of calcium ion transportGO:005192420.010
epithelial cell developmentGO:0002064420.010
cellular ketone metabolic processGO:0042180110.010
cell adhesionGO:0007155400.010
Mouse
pigment cell differentiationGO:0050931380.010
multicellular organism reproductionGO:0032504350.010
negative regulation of multi organism processGO:004390130.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
cellular amino acid metabolic processGO:000652070.010
establishment or maintenance of cell polarityGO:0007163290.010
embryonic retina morphogenesis in camera type eyeGO:0060059220.010
female gonad developmentGO:000858540.010
cellular response to xenobiotic stimulusGO:0071466350.010
regulation of macromolecule biosynthetic processGO:00105562250.010
membrane organizationGO:0061024210.010
regulation of nitrogen compound metabolic processGO:00511712510.010
protein complex disassemblyGO:004324110.010
muscle system processGO:0003012200.010

dspa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.409
Human
muscle tissue diseaseDOID:6600.409
Human
disease of anatomical entityDOID:700.409
Human
cardiomyopathyDOID:005070000.409
Human
heart diseaseDOID:11400.409
Human
muscular diseaseDOID:008000000.409
Human
myopathyDOID:42300.409
Human
musculoskeletal system diseaseDOID:1700.409
Human
intrinsic cardiomyopathyDOID:006003600.358
Human