Danio rerio

33 known processes

pde6c

phosphodiesterase 6C, cGMP-specific, cone, alpha prime

(Aliases: zgc:73085,MGC73085)

pde6c biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
photoreceptor cell outer segment organizationGO:003584590.877
single organism organelle organizationGO:19025891990.816
detection of light stimulusGO:0009583120.810
photoreceptor cell differentiationGO:0046530550.809
photoreceptor cell developmentGO:0042461400.715
eye morphogenesisGO:00485921440.693
camera type eye developmentGO:00430102220.673
cellular component movementGO:00069283350.666
sensory organ developmentGO:00074233930.622
generation of neuronsGO:00486993850.610
nonmotile primary cilium assemblyGO:003505820.609
retina development in camera type eyeGO:00600411460.594
camera type eye photoreceptor cell differentiationGO:0060219190.586
signal transductionGO:00071654550.564
detection of external stimulusGO:0009581240.514
phototransduction visible lightGO:000760320.512
eye developmentGO:00016542770.504
sensory organ morphogenesisGO:00905962000.462
tube morphogenesisGO:00352393490.399
retina homeostasisGO:0001895120.360
detection of abiotic stimulusGO:0009582240.337
retina morphogenesis in camera type eyeGO:0060042790.311
eye photoreceptor cell developmentGO:0042462300.298
camera type eye morphogenesisGO:00485931080.296
eye photoreceptor cell differentiationGO:0001754450.290
response to abiotic stimulusGO:00096281220.273
cellular response to radiationGO:007147840.268
localization of cellGO:00516742440.253
receptor recyclingGO:000188140.236
system processGO:00030081850.235
absorption of visible lightGO:001603820.233
regulation of chemokine activityGO:190013630.224
small molecule metabolic processGO:0044281770.223
central nervous system developmentGO:00074173870.216
apical protein localizationGO:004517660.209
neuron developmentGO:00486662620.207
sensory perceptionGO:0007600390.189
response to external stimulusGO:00096052640.181
phototransductionGO:000760220.165
anatomical structure homeostasisGO:0060249360.165
response to light stimulusGO:0009416460.163
transmission of nerve impulseGO:0019226190.159
cell migrationGO:00164772370.157
immune system processGO:00023762410.144
phosphorus metabolic processGO:00067931090.142
tissue homeostasisGO:0001894250.140
establishment of endothelial blood brain barrierGO:001404520.140
regulation of smoothened signaling pathwayGO:0008589180.135
regulation of protein bindingGO:004339330.135
regulation of localizationGO:00328791040.131
cellular component assemblyGO:00226071700.130
detection of stimulusGO:0051606290.128
ameboidal type cell migrationGO:00016671430.127
light adaptionGO:003636710.125
regulation of cell communicationGO:00106462320.123
locomotionGO:00400113130.123
retina layer formationGO:0010842240.122
brain developmentGO:00074202930.119
agingGO:000756820.118
smoothened signaling pathwayGO:0007224300.118
retinal cone cell developmentGO:004654980.117
phosphate containing compound metabolic processGO:00067961080.115
cell motilityGO:00488702440.114
cellular response to light stimulusGO:007148240.113
embryonic heart tube developmentGO:00350501330.112
inositol lipid mediated signalingGO:004801720.112
regulation of bindingGO:005109830.112
visual perceptionGO:0007601170.111
multicellular organismal signalingGO:0035637220.111
response to light intensityGO:000964210.110
cell surface receptor signaling pathwayGO:00071663250.109
spindle organizationGO:000705150.109
neurological system processGO:0050877620.107
cellular nitrogen compound metabolic processGO:00346412900.106
neuron differentiationGO:00301823530.106
organelle localizationGO:0051640490.104
protein desumoylationGO:001692610.102
protein complex subunit organizationGO:0071822460.101
embryo development ending in birth or egg hatchingGO:00097922710.100
organelle organizationGO:00069962270.100
multicellular organism growthGO:003526440.099
cellular component morphogenesisGO:00329893360.098
regulation of receptor recyclingGO:000191930.093
neural retina developmentGO:0003407490.093
protein modification processGO:00362111000.092
cell morphogenesisGO:00009022890.091
positive regulation of map kinase activityGO:004340630.090
stem cell divisionGO:001714510.089
heterocycle metabolic processGO:00464832900.088
single organism metabolic processGO:00447102170.087
detection of visible lightGO:0009584120.085
establishment of endothelial barrierGO:006102830.085
nucleocytoplasmic transportGO:000691340.084
cellular component biogenesisGO:00440851780.082
negative regulation of biological processGO:00485193040.080
negative regulation of protein phosphorylationGO:000193340.074
neuronal action potentialGO:0019228180.072
regulation of cellular amine metabolic processGO:003323800.072
nucleobase containing compound metabolic processGO:00061392740.071
negative regulation of cell cell adhesion mediated by cadherinGO:200004820.071
neuron neuron synaptic transmissionGO:000727010.070
cellular protein modification processGO:00064641000.068
regulation of peptidyl tyrosine phosphorylationGO:005073010.067
axon ensheathment in central nervous systemGO:003229120.066
regulation of biological qualityGO:00650082630.065
cytoskeleton organizationGO:0007010960.064
establishment of organelle localizationGO:0051656450.063
cell part morphogenesisGO:00329902460.063
sensory perception of light stimulusGO:0050953190.063
cell cell adhesion mediated by cadherinGO:004433150.063
regulation of guanylate cyclase activityGO:003128260.063
light absorptionGO:001603720.061
larval developmentGO:000216420.061
regulation of metabolic processGO:00192223590.061
establishment of localizationGO:00512342440.061
dorsal motor nucleus of vagus nerve developmentGO:002174440.060
sensory perception of chemical stimulusGO:000760630.060
neuroblast proliferationGO:000740520.060
cellular macromolecule metabolic processGO:00442603910.059
cgmp metabolic processGO:004606870.059
purine nucleotide metabolic processGO:0006163270.058
atp catabolic processGO:000620040.058
organophosphate metabolic processGO:0019637370.053
positive regulation of cgmp biosynthetic processGO:003082860.053
positive regulation of cellular processGO:00485222010.052
retinal cone cell differentiationGO:0042670120.052
cell projection organizationGO:00300302840.052
cyclic nucleotide metabolic processGO:0009187180.052
cortical cytoskeleton organizationGO:003086510.051
mitotic cell cycle processGO:1903047480.051
stem cell proliferationGO:007208940.050
ribonucleotide biosynthetic processGO:0009260200.050
photoreceptor cell fate commitmentGO:004655210.050
regulation of protein modification by small protein conjugation or removalGO:190332030.049
heart developmentGO:00075073130.048
single organism transportGO:00447652060.048
establishment of localization in cellGO:0051649770.048
ribose phosphate metabolic processGO:0019693270.047
cell projection morphogenesisGO:00488582440.047
nuclear transportGO:005116940.047
microtubule based processGO:0007017600.046
cellular amino acid metabolic processGO:000652070.046
establishment of blood brain barrierGO:006085620.046
protein metabolic processGO:00195381830.046
transportGO:00068102200.046
regulation of signal transductionGO:00099662250.045
cell migration involved in gastrulationGO:0042074790.045
negative regulation of response to stimulusGO:00485851040.045
homeostatic processGO:00425921420.043
regulation of signalingGO:00230512350.042
protein modification by small protein removalGO:007064610.042
medulla oblongata developmentGO:002155040.042
organic cyclic compound metabolic processGO:19013603010.041
purine containing compound biosynthetic processGO:0072522200.041
protein complex assemblyGO:0006461300.041
establishment of spindle localizationGO:0051293120.041
biosynthetic processGO:00090582940.041
cellular component disassemblyGO:002241110.041
rho protein signal transductionGO:000726650.040
digestive tract developmentGO:00485652650.040
meiotic nuclear divisionGO:000712640.040
purine nucleotide biosynthetic processGO:0006164200.039
cellular amine metabolic processGO:004410620.039
positive regulation of biological processGO:00485182530.039
ear developmentGO:00435831270.038
determination of bilateral symmetryGO:00098552040.038
regulation of nucleoside metabolic processGO:000911820.038
cellular biosynthetic processGO:00442492860.038
single organism localizationGO:19025782250.037
carbohydrate derivative metabolic processGO:1901135610.037
asymmetric protein localizationGO:000810560.037
regulation of cellular ketone metabolic processGO:001056570.037
embryonic axis specificationGO:0000578120.035
determination of left right symmetryGO:00073681790.035
regulation of multicellular organismal processGO:00512392770.035
head developmentGO:00603223030.035
muscle structure developmentGO:00610611960.035
spindle localizationGO:0051653120.035
morphogenesis of an epithelial sheetGO:0002011490.033
positive regulation of transportGO:005105020.033
maintenance of locationGO:005123540.033
nuclear migrationGO:000709730.033
g protein coupled receptor signaling pathwayGO:0007186740.033
intracellular signal transductionGO:0035556850.032
embryonic retina morphogenesis in camera type eyeGO:0060059220.032
neurotransmitter transportGO:000683620.031
regulation of establishment of protein localizationGO:007020140.031
regulation of primary metabolic processGO:00800903110.031
establishment of mitotic spindle orientationGO:0000132100.031
nucleotide metabolic processGO:0009117280.031
positive regulation of metabolic processGO:00098931080.031
hematopoietic or lymphoid organ developmentGO:00485341910.031
regulation of catalytic activityGO:0050790550.031
growthGO:00400071740.031
amine metabolic processGO:000930820.030
regulation of inflammatory responseGO:005072720.030
renal filtrationGO:0097205100.030
response to drugGO:004249330.030
rhodopsin mediated signaling pathwayGO:001605610.030
morphogenesis of an epitheliumGO:00020093330.030
positive regulation of guanylate cyclase activityGO:003128460.030
regulation of cytoplasmic transportGO:190364940.030
nitrogen compound metabolic processGO:00068073190.029
action potentialGO:0001508190.029
chordate embryonic developmentGO:00430092710.029
regulation of sequestering of calcium ionGO:005128240.028
establishment of synaptic vesicle localizationGO:009748010.028
single organismal cell cell adhesionGO:0016337290.028
specification of symmetryGO:00097992040.028
nucleobase containing small molecule metabolic processGO:0055086320.028
cellular nitrogen compound biosynthetic processGO:00442712180.028
response to radiationGO:0009314510.028
macromolecule modificationGO:00434121110.027
cilium morphogenesisGO:0060271850.027
regulation of protein transportGO:005122330.027
response to stressGO:00069502630.026
cortical actin cytoskeleton organizationGO:003086610.026
angiogenesisGO:00015251580.026
regulation of locomotionGO:0040012550.026
multicellular organismal response to stressGO:003355520.026
establishment of spindle orientationGO:0051294100.025
regulation of intracellular protein transportGO:003315730.025
regulation of multicellular organism growthGO:004001440.025
nuclear exportGO:005116810.025
pyruvate metabolic processGO:000609010.025
positive regulation of axon extension involved in axon guidanceGO:004884210.025
macromolecular complex subunit organizationGO:0043933740.025
negative regulation of epithelial cell proliferationGO:005068010.025
regulation of cellular amino acid metabolic processGO:000652100.025
guanosine containing compound metabolic processGO:190106840.025
heterocycle biosynthetic processGO:00181302150.025
regulation of neurotransmitter secretionGO:004692810.025
guanosine containing compound catabolic processGO:190106920.024
establishment or maintenance of cell polarityGO:0007163290.024
fatty acid elongationGO:003049710.024
negative regulation of cellular processGO:00485232830.024
macromolecular complex assemblyGO:0065003350.024
negative regulation of defense responseGO:003134820.024
hemopoiesisGO:00300971830.024
regulation of chemotaxisGO:0050920180.024
embryonic pattern specificationGO:0009880440.024
macromolecule localizationGO:0033036540.024
cell cycle processGO:0022402530.023
single organism biosynthetic processGO:0044711710.023
gtp catabolic processGO:000618420.023
cyclic nucleotide biosynthetic processGO:0009190180.023
regulation of macromolecule metabolic processGO:00602553170.023
pronuclear migrationGO:003504610.022
retinal pigment epithelium developmentGO:000340680.022
meiotic cell cycle processGO:190304630.022
single fertilizationGO:000733830.022
positive regulation of cellular metabolic processGO:0031325940.022
phosphorylationGO:0016310690.022
enzyme linked receptor protein signaling pathwayGO:00071671060.022
cellular localizationGO:0051641970.021
phagocytosisGO:000690930.021
glycerophospholipid biosynthetic processGO:004647410.021
protein complex biogenesisGO:0070271300.021
synapsisGO:000712910.021
synaptic vesicle endocytosisGO:004848810.021
thermosensory behaviorGO:004004010.021
cell morphogenesis involved in neuron differentiationGO:00486671630.021
nucleobase containing compound biosynthetic processGO:00346542050.021
cyclic purine nucleotide metabolic processGO:0052652180.021
cellular ketone metabolic processGO:0042180110.020
neuron projection developmentGO:00311751800.020
convergent extensionGO:00600261180.020
androgen metabolic processGO:000820920.020
regulation of cellular component organizationGO:0051128860.020
gene expressionGO:00104672520.020
retinal cell programmed cell deathGO:004666620.020
response to chemicalGO:00422213200.020
polyol metabolic processGO:001975110.020
synaptic vesicle localizationGO:009747910.020
purine ribonucleotide metabolic processGO:0009150270.020
regulation of nucleocytoplasmic transportGO:004682220.019
regulation of cellular metabolic processGO:00313233200.019
ribosome assemblyGO:004225510.019
response to amphetamineGO:000197510.019
myeloid cell developmentGO:0061515320.019
digestive system developmentGO:00551232890.019
response to amineGO:001407510.019
organonitrogen compound biosynthetic processGO:1901566470.019
positive regulation of cyclic nucleotide biosynthetic processGO:003080480.019
immune system developmentGO:00025201910.019
activation of mapk activityGO:000018730.019
regulation of gtp catabolic processGO:003312420.019
embryonic organ developmentGO:00485683810.018
rna metabolic processGO:00160702190.018
organonitrogen compound metabolic processGO:1901564740.018
positive regulation of response to stimulusGO:0048584800.018
spindle assemblyGO:005122520.018
negative regulation of signalingGO:0023057960.018
positive regulation of cell communicationGO:0010647560.018
glomerular filtrationGO:000309460.018
epiboly involved in gastrulation with mouth forming secondGO:0055113350.018
actin filament based processGO:0030029640.018
glial cell differentiationGO:0010001420.018
cell adhesionGO:0007155400.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of response to stimulusGO:00485832690.017
photoreceptor cell maintenanceGO:0045494110.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
purine nucleoside monophosphate catabolic processGO:000912840.017
regulation of nitrogen compound metabolic processGO:00511712510.017
nuclear divisionGO:0000280230.017
regulation of cellular component movementGO:0051270550.017
regulation of dendrite morphogenesisGO:004881430.017
calcium mediated signalingGO:001972220.016
vitamin a metabolic processGO:000677610.016
regulation of cellular biosynthetic processGO:00313262450.016
negative regulation of signal transductionGO:0009968940.016
regulation of cgmp biosynthetic processGO:003082660.016
cell cycleGO:0007049930.016
single organism cell adhesionGO:0098602290.016
negative regulation of kinase activityGO:003367340.016
cellular aromatic compound metabolic processGO:00067252950.016
embryonic heart tube morphogenesisGO:00031431080.015
positive regulation of signalingGO:0023056560.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
auditory receptor cell fate determinationGO:004266820.015
microtubule cytoskeleton organizationGO:0000226330.015
establishment of mitotic spindle localizationGO:0040001120.015
regulation of nucleotide catabolic processGO:003081120.015
locomotor rhythmGO:004547530.015
protein phosphorylationGO:0006468470.015
cytokinesisGO:000091030.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
cellular component assembly involved in morphogenesisGO:00109271070.015
regulation of dna replicationGO:000627530.014
positive regulation of cellular component biogenesisGO:004408930.014
lamellipodium organizationGO:009758110.014
mitotic cell cycleGO:0000278640.014
cgmp biosynthetic processGO:000618270.014
purine containing compound metabolic processGO:0072521290.014
actomyosin structure organizationGO:0031032530.014
anterior posterior pattern specificationGO:00099521520.014
establishment of melanosome localizationGO:0032401190.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
axon ensheathmentGO:0008366180.014
ensheathment of neuronsGO:0007272180.014
neurotransmitter secretionGO:000726920.014
positive regulation of cell cycleGO:004578730.013
neural tube formationGO:0001841160.013
cilium organizationGO:0044782710.013
epithelial cell developmentGO:0002064420.013
olfactory lobe developmentGO:002198840.013
synaptic vesicle transportGO:004848910.013
intestinal epithelial structure maintenanceGO:006072970.013
ribonucleotide metabolic processGO:0009259270.013
cell fate commitmentGO:0045165990.013
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.013
fertilizationGO:000956630.013
digestive tract morphogenesisGO:00485462310.013
programmed cell deathGO:00125011190.012
cellular lipid metabolic processGO:0044255360.012
transcription dna templatedGO:00063511810.012
regulation of membrane potentialGO:0042391230.012
ribonucleoside monophosphate catabolic processGO:000915840.012
developmental programmed cell deathGO:001062340.012
protein complex disassemblyGO:004324110.012
negative regulation of protein kinase activityGO:000646940.012
carboxylic acid metabolic processGO:0019752220.012
regulation of intracellular signal transductionGO:1902531570.012
response to uvGO:000941130.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.012
regulation of cgmp metabolic processGO:003082360.012
multicellular organismal homeostasisGO:0048871290.012
developmental growthGO:00485891660.012
regulation of cell migrationGO:0030334400.012
regulation of organelle assemblyGO:190211540.012
regulation of phosphate metabolic processGO:0019220430.012
regulation of neurotransmitter transportGO:005158810.012
detection of light stimulus involved in visual perceptionGO:005090870.012
centrosome duplicationGO:005129810.011
cell deathGO:00082191210.011
protein heterooligomerizationGO:005129110.011
vesicle mediated transportGO:0016192220.011
forebrain morphogenesisGO:004885360.011
sensory perception of soundGO:000760590.011
modification dependent macromolecule catabolic processGO:004363230.011
lateral line ganglion developmentGO:004889020.011
carbohydrate homeostasisGO:003350010.011
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.011
forebrain anterior posterior pattern specificationGO:002179730.011
regulation of cell cell adhesionGO:0022407130.011
homeostasis of number of cells within a tissueGO:004887340.011
cell substrate adherens junction assemblyGO:000704510.011
positive regulation of protein complex assemblyGO:003133420.011
wnt signaling pathwayGO:0016055800.011
cellular response to reactive oxygen speciesGO:003461420.011
reflexGO:006000420.011
actin cytoskeleton organizationGO:0030036630.011
negative regulation of macromolecule metabolic processGO:0010605760.011
gastrulation with mouth forming secondGO:0001702440.011
fatty acid transportGO:001590810.011
phosphatidylinositol metabolic processGO:004648870.011
deathGO:00162651210.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
regulation of skeletal muscle tissue developmentGO:004864140.011
inner ear developmentGO:00488391260.010
embryonic organ morphogenesisGO:00485622740.010
positive regulation of cell divisionGO:005178120.010
cell proliferationGO:0008283800.010
cellular protein complex disassemblyGO:004362410.010
regulation of dendrite developmentGO:005077330.010
cellular response to oxygen levelsGO:007145310.010
negative regulation of catabolic processGO:000989530.010

pde6c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.720
eye and adnexa diseaseDOID:149200.720
disease of anatomical entityDOID:700.720
retinal diseaseDOID:567900.720
sensory system diseaseDOID:005015500.720
nervous system diseaseDOID:86300.720
retinal degenerationDOID:846600.116
retinitis pigmentosaDOID:1058400.116
congenital nervous system abnormalityDOID:249000.012
physical disorderDOID:008001500.012
neuromuscular diseaseDOID:44000.011
charcot marie tooth diseaseDOID:1059500.011
neuropathyDOID:87000.011
musculoskeletal system diseaseDOID:1700.011