Danio rerio

0 known processes

apip

APAF1 interacting protein

(Aliases: zgc:103619)

apip biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.089
agingGO:000756820.055
positive regulation of transportGO:005105020.044
multicellular organism growthGO:003526440.039
maintenance of locationGO:005123540.036
proteolysis involved in cellular protein catabolic processGO:005160330.035
guanosine containing compound catabolic processGO:190106920.034
autophagyGO:000691440.034
cellular response to nutrient levelsGO:003166920.033
nitrogen compound metabolic processGO:00068073190.032
cellular response to extracellular stimulusGO:003166820.031
cellular response to external stimulusGO:007149620.031
regulation of multicellular organism growthGO:004001440.031
gtp metabolic processGO:004603940.031
neuron differentiationGO:00301823530.031
organelle fusionGO:004828430.031
guanosine containing compound metabolic processGO:190106840.031
carboxylic acid catabolic processGO:004639530.031
response to chemicalGO:00422213200.031
cognitionGO:005089010.031
cellular response to starvationGO:000926710.031
mitochondrion organizationGO:000700540.030
ubiquitin dependent protein catabolic processGO:000651130.030
establishment of protein localization to organelleGO:007259440.029
amine metabolic processGO:000930820.029
small molecule metabolic processGO:0044281770.029
organic acid catabolic processGO:001605430.029
phagocytosisGO:000690930.028
modification dependent protein catabolic processGO:001994130.028
regulation of protein complex assemblyGO:004325430.028
cellular protein catabolic processGO:004425740.028
proteasomal protein catabolic processGO:001049820.028
positive regulation of cellular component biogenesisGO:004408930.028
single organism membrane fusionGO:004480120.027
protein localization to nucleusGO:003450430.027
generation of neuronsGO:00486993850.027
positive regulation of catabolic processGO:000989640.027
cellular macromolecule metabolic processGO:00442603910.026
membrane fusionGO:006102520.026
protein importGO:001703830.026
meiotic cell cycle processGO:190304630.026
nucleocytoplasmic transportGO:000691340.026
cell part morphogenesisGO:00329902460.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
nuclear transportGO:005116940.026
organic cyclic compound metabolic processGO:19013603010.025
cellular amine metabolic processGO:004410620.025
cellular nitrogen compound metabolic processGO:00346412900.025
heterocycle metabolic processGO:00464832900.025
xenobiotic metabolic processGO:000680540.025
protein targeting to nucleusGO:004474430.025
meiotic nuclear divisionGO:000712640.025
modification dependent macromolecule catabolic processGO:004363230.025
regulation of establishment of protein localizationGO:007020140.025
gtp catabolic processGO:000618420.024
regulation of meiotic cell cycleGO:005144510.024
cytokinesisGO:000091030.024
regulation of metal ion transportGO:001095940.024
single organism metabolic processGO:00447102170.024
small molecule catabolic processGO:004428230.024
positive regulation of cellular catabolic processGO:003133130.024
cell projection organizationGO:00300302840.024
positive regulation of cell cycleGO:004578730.024
lipid storageGO:001991510.024
regulation of bindingGO:005109830.023
regulation of protein targetingGO:190353320.023
nucleobase containing compound metabolic processGO:00061392740.023
negative regulation of protein phosphorylationGO:000193340.023
regulation of protein transportGO:005122330.023
secondary metabolic processGO:001974830.023
single organism nuclear importGO:190259330.023
neuron developmentGO:00486662620.023
endosomal transportGO:001619720.023
extrinsic apoptotic signaling pathwayGO:009719130.023
gene expressionGO:00104672520.022
cellular aromatic compound metabolic processGO:00067252950.022
regulation of transporter activityGO:003240920.022
stem cell maintenanceGO:001982740.022
cell projection morphogenesisGO:00488582440.022
regulation of primary metabolic processGO:00800903110.022
nucleic acid metabolic processGO:00903042440.022
response to external stimulusGO:00096052640.022
organonitrogen compound metabolic processGO:1901564740.021
neurotransmitter secretionGO:000726920.021
regulation of cytokine productionGO:000181730.021
protein import into nucleusGO:000660630.021
protein localization to plasma membraneGO:007265910.021
nuclear importGO:005117030.021
regulation of cellular amine metabolic processGO:003323800.021
morphogenesis of an epitheliumGO:00020093330.021
regulation of cytoplasmic transportGO:190364940.021
negative regulation of biological processGO:00485193040.020
stem cell proliferationGO:007208940.020
signal transductionGO:00071654550.020
cellular component morphogenesisGO:00329893360.020
rna metabolic processGO:00160702190.020
macroautophagyGO:001623610.020
chordate embryonic developmentGO:00430092710.020
regulation of cellular amino acid metabolic processGO:000652100.020
regulation of nitrogen compound metabolic processGO:00511712510.020
golgi vesicle transportGO:004819330.020
establishment of localizationGO:00512342440.020
cellular component movementGO:00069283350.020
regulation of metabolic processGO:00192223590.020
neurotransmitter transportGO:000683620.019
organic acid metabolic processGO:0006082310.019
vasculature developmentGO:00019442780.019
regulation of protein localization to nucleusGO:190018020.019
organic substance biosynthetic processGO:19015762890.019
regulation of synaptic plasticityGO:004816710.019
regulation of nucleotide catabolic processGO:003081120.019
cellular component disassemblyGO:002241110.019
cellular amino acid metabolic processGO:000652070.019
embryo development ending in birth or egg hatchingGO:00097922710.019
regulation of synapse assemblyGO:005196330.019
protein metabolic processGO:00195381830.019
regulation of macromolecule metabolic processGO:00602553170.019
regulation of purine nucleotide catabolic processGO:003312120.019
positive regulation of secretionGO:005104710.019
tube morphogenesisGO:00352393490.019
regulation of protein import into nucleusGO:004230620.019
positive regulation of purine nucleotide catabolic processGO:003312310.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of nucleocytoplasmic transportGO:004682220.018
response to stressGO:00069502630.018
oxoacid metabolic processGO:0043436310.018
protein secretionGO:000930610.018
regulation of intracellular protein transportGO:003315730.018
organelle organizationGO:00069962270.018
carboxylic acid metabolic processGO:0019752220.018
regulation of cellular ketone metabolic processGO:001056570.018
cell substrate adhesionGO:003158940.018
internal protein amino acid acetylationGO:000647520.018
biosynthetic processGO:00090582940.018
cellular ketone metabolic processGO:0042180110.018
regulation of cellular metabolic processGO:00313233200.018
axon developmentGO:00615641660.018
response to drugGO:004249330.018
sensory organ developmentGO:00074233930.017
regulation of signalingGO:00230512350.017
membrane invaginationGO:001032410.017
i kappab kinase nf kappab signalingGO:000724940.017
regulation of gtp catabolic processGO:003312420.017
regulation of cell communicationGO:00106462320.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
compound eye developmentGO:004874920.017
negative regulation of protein kinase activityGO:000646940.017
neuron projection developmentGO:00311751800.017
cytoskeleton dependent cytokinesisGO:006164030.017
single organism localizationGO:19025782250.017
embryonic organ developmentGO:00485683810.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of cell shapeGO:000836010.017
regulation of autophagyGO:001050630.017
negative regulation of kinase activityGO:003367340.017
cell morphogenesisGO:00009022890.017
heterocycle biosynthetic processGO:00181302150.017
cellular amide metabolic processGO:004360340.017
centrosome organizationGO:005129710.016
transportGO:00068102200.016
aromatic compound biosynthetic processGO:00194382170.016
phagocytosis engulfmentGO:000691110.016
response to uvGO:000941130.016
positive regulation of gtp catabolic processGO:003312610.016
macromolecular complex disassemblyGO:003298410.016
peptidyl lysine acetylationGO:001839420.016
interspecies interaction between organismsGO:004441940.016
meiotic chromosome segregationGO:004513230.016
locomotionGO:00400113130.016
regulation of rna metabolic processGO:00512522240.016
synaptic growth at neuromuscular junctionGO:005112420.016
peptide metabolic processGO:000651810.016
organic cyclic compound biosynthetic processGO:19013622230.016
head developmentGO:00603223030.016
regulation of cell activationGO:005086510.016
negative regulation of cellular processGO:00485232830.016
cellular response to chemical stimulusGO:00708871570.016
lipid catabolic processGO:001604240.016
central nervous system developmentGO:00074173870.016
axonogenesisGO:00074091520.016
regulation of stem cell proliferationGO:007209120.016
nucleobase containing compound biosynthetic processGO:00346542050.016
cellular protein metabolic processGO:00442671290.016
positive regulation of secretion by cellGO:190353210.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
chemosensory behaviorGO:000763510.016
positive regulation of dna metabolic processGO:005105410.016
macromolecule biosynthetic processGO:00090592270.016
positive regulation of nucleoside metabolic processGO:004597910.015
positive regulation of biological processGO:00485182530.015
regulation of protein catabolic processGO:004217610.015
positive regulation of nucleotide catabolic processGO:003081310.015
blood vessel developmentGO:00015682460.015
regulation of dendrite developmentGO:005077330.015
brain developmentGO:00074202930.015
multi organism cellular processGO:004476420.015
tissue remodelingGO:004877140.015
exocytosisGO:000688710.015
positive regulation of gtpase activityGO:004354710.015
cellular carbohydrate metabolic processGO:004426240.015
synaptic vesicle transportGO:004848910.015
single organism transportGO:00447652060.015
regulation of reproductive processGO:200024140.015
protein complex disassemblyGO:004324110.015
ribonucleoside monophosphate catabolic processGO:000915840.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
cell morphogenesis involved in differentiationGO:00009041950.015
regulation of multicellular organismal processGO:00512392770.015
regulation of gtpase activityGO:004308720.015
nucleic acid templated transcriptionGO:00976591810.015
cellular component biogenesisGO:00440851780.015
spermatid developmentGO:000728620.015
regulation of synapse organizationGO:005080730.015
protein acetylationGO:000647320.015
synaptic vesicle localizationGO:009747910.015
production of molecular mediator of immune responseGO:000244020.015
negative regulation of cytoplasmic transportGO:190365020.015
calcium ion transport into cytosolGO:006040230.015
cell surface receptor signaling pathwayGO:00071663250.014
heart developmentGO:00075073130.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
regulation of ion transmembrane transporter activityGO:003241220.014
protein polyubiquitinationGO:000020940.014
apoptotic processGO:00069151160.014
rna biosynthetic processGO:00327741810.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
atp catabolic processGO:000620040.014
regulation of response to stimulusGO:00485832690.014
cellular response to molecule of bacterial originGO:007121930.014
fertilizationGO:000956630.014
positive regulation of jnk cascadeGO:004633030.014
adult behaviorGO:003053420.014
positive regulation of cytokine productionGO:000181920.014
mitotic dna integrity checkpointGO:004477440.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
negative regulation of mapk cascadeGO:004340940.014
single fertilizationGO:000733830.014
sequestering of calcium ionGO:005120830.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
regulation of cellular biosynthetic processGO:00313262450.014
developmental programmed cell deathGO:001062340.014
regulation of biosynthetic processGO:00098892500.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
digestive tract morphogenesisGO:00485462310.014
regulation of neurotransmitter transportGO:005158810.013
response to nutrientGO:000758430.013
positive regulation of cell activationGO:005086710.013
organelle assemblyGO:00709251100.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
positive regulation of immune effector processGO:000269930.013
positive regulation of protein complex assemblyGO:003133420.013
stem cell divisionGO:001714510.013
spermatid differentiationGO:004851520.013
actin polymerization or depolymerizationGO:000815420.013
positive regulation of cytoskeleton organizationGO:005149530.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
neuron neuron synaptic transmissionGO:000727010.013
regulation of mrna processingGO:005068430.013
protein acylationGO:004354330.013
cellular response to radiationGO:007147840.013
cellular lipid catabolic processGO:004424230.013
regulation of calcium ion transportGO:005192420.013
negative regulation of sequestering of calcium ionGO:005128340.013
response to carbohydrateGO:000974330.013
regulation of sequestering of calcium ionGO:005128240.013
negative regulation of catabolic processGO:000989530.013
lateral inhibitionGO:004633110.013
growthGO:00400071740.013
response to alkaloidGO:004327920.013
locomotor rhythmGO:004547530.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
viral processGO:001603210.013
neuron projection morphogenesisGO:00488121610.013
sequestering of metal ionGO:005123830.013
alcohol biosynthetic processGO:004616520.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
cellular response to biotic stimulusGO:007121630.013
internal peptidyl lysine acetylationGO:001839320.013
regulation of rna biosynthetic processGO:20011412130.013
monocarboxylic acid catabolic processGO:007232930.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
regulation of erk1 and erk2 cascadeGO:007037240.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
response to monosaccharideGO:003428430.013
regulation of transcription dna templatedGO:00063552130.012
response to hexoseGO:000974630.012
positive regulation of cellular amine metabolic processGO:003324000.012
single organism organelle organizationGO:19025891990.012
regulation of protein ubiquitinationGO:003139630.012
regulation of transmembrane transporter activityGO:002289820.012
primary neural tube formationGO:001402010.012
negative regulation of intracellular transportGO:003238730.012
transcription dna templatedGO:00063511810.012
cellular localizationGO:0051641970.012
mitotic g2 m transition checkpointGO:004481830.012
peptidyl serine modificationGO:001820920.012
cellular biosynthetic processGO:00442492860.012
cellular response to stressGO:0033554620.012
lipid oxidationGO:003444010.012
peptide transportGO:001583310.012
system processGO:00030081850.012
developmental growthGO:00485891660.012
protein homooligomerizationGO:005126030.012
regulation of signal transductionGO:00099662250.012
blood vessel morphogenesisGO:00485142160.012
carbohydrate homeostasisGO:003350010.012
programmed cell deathGO:00125011190.012
establishment of synaptic vesicle localizationGO:009748010.012
deathGO:00162651210.012
regulation of response to biotic stimulusGO:000283120.012
negative regulation of cytokine productionGO:000181810.012
peptidyl serine phosphorylationGO:001810510.012
adherens junction organizationGO:003433240.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
g1 s transition of mitotic cell cycleGO:000008210.012
establishment of protein localization to plasma membraneGO:009000210.012
nucleoside monophosphate catabolic processGO:000912540.012
cell deathGO:00082191210.012
tube closureGO:006060610.012
positive regulation of stress activated mapk cascadeGO:003287430.012
female meiotic divisionGO:000714320.012
response to topologically incorrect proteinGO:003596620.012
negative regulation of protein transportGO:005122430.012
rna localizationGO:000640340.012
vacuolar transportGO:000703420.012
cellular component assemblyGO:00226071700.012
mitotic dna damage checkpointGO:004477340.012
response to glucoseGO:000974930.012
regulation of gene expressionGO:00104682650.012
regulation of multicellular organismal developmentGO:20000262230.012
rna transportGO:005065820.012
regulation of developmental processGO:00507932470.012
multi organism processGO:00517041340.012
negative regulation of protein complex assemblyGO:003133310.012
mitochondrial transportGO:000683920.012
centrosome cycleGO:000709810.012
immune system processGO:00023762410.012
cellular response to xenobiotic stimulusGO:0071466350.011
determination of left right symmetryGO:00073681790.011
cell migrationGO:00164772370.011
female sex differentiationGO:004666040.011
cytoplasm organizationGO:000702840.011
negative regulation of cellular catabolic processGO:003133030.011
cytosolic calcium ion transportGO:006040130.011
purine nucleoside monophosphate catabolic processGO:000912840.011
cell matrix adhesionGO:000716040.011
regulation of neural precursor cell proliferationGO:200017730.011
leukocyte proliferationGO:007066110.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
cilium organizationGO:0044782710.011
gland developmentGO:00487321430.011
hemopoiesisGO:00300971830.011
mononuclear cell proliferationGO:003294310.011
regulation of protein polymerizationGO:003227120.011
translational initiationGO:000641330.011
regulation of circadian rhythmGO:004275240.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
somite developmentGO:0061053960.011
cytokinetic processGO:003250620.011
regulation of neurotransmitter secretionGO:004692810.011
regionalizationGO:00030022740.011
glucose homeostasisGO:004259310.011
cellular response to hypoxiaGO:007145610.011
cilium assemblyGO:0042384580.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
b cell activationGO:004211320.011
cell cycle g1 s phase transitionGO:004484310.011
negative regulation of intracellular protein transportGO:009031730.011
negative regulation of signal transductionGO:0009968940.011
double strand break repairGO:000630230.011
positive regulation of cellular processGO:00485222010.011
homeostatic processGO:00425921420.011
eye developmentGO:00016542770.011
nucleic acid transportGO:005065720.011
regulation of chromosome segregationGO:005198310.011
regulation of neurogenesisGO:0050767870.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
protein polymerizationGO:005125840.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
digestive system developmentGO:00551232890.011
response to unfolded proteinGO:000698620.011
sleepGO:003043110.011
response to hydrogen peroxideGO:004254230.011
determination of bilateral symmetryGO:00098552040.011
cellular response to oxygen levelsGO:007145310.011
cell motilityGO:00488702440.011
female gonad developmentGO:000858540.011
erk1 and erk2 cascadeGO:007037140.011
nucleobase containing compound transportGO:001593120.010
convergent extensionGO:00600261180.010
er to golgi vesicle mediated transportGO:000688810.010
regulation of biological qualityGO:00650082630.010
muscle cell differentiationGO:00426921390.010
regulation of dna templated transcription elongationGO:003278430.010
response to organic substanceGO:00100331530.010
phosphate containing compound metabolic processGO:00067961080.010
neuroblast proliferationGO:000740520.010
negative regulation of cell communicationGO:0010648960.010
cellular response to topologically incorrect proteinGO:003596720.010
regulation of sodium ion transportGO:000202820.010
signal transduction in absence of ligandGO:003803410.010
regulation of stem cell differentiationGO:200073640.010
neuromuscular synaptic transmissionGO:000727420.010
antimicrobial humoral responseGO:001973020.010
specification of symmetryGO:00097992040.010
intracellular mrna localizationGO:000829810.010
cellular response to decreased oxygen levelsGO:003629410.010
muscle structure developmentGO:00610611960.010
negative regulation of multi organism processGO:004390130.010
g2 dna damage checkpointGO:003157230.010
ovulation cycleGO:004269820.010
negative regulation of signalingGO:0023057960.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
somatic stem cell maintenanceGO:003501910.010
cellular macromolecule biosynthetic processGO:00346452240.010
regulation of epithelial cell proliferationGO:005067830.010
positive regulation of multi organism processGO:004390230.010
cellular component assembly involved in morphogenesisGO:00109271070.010
synaptic vesicle recyclingGO:003646510.010
regulation of apoptotic processGO:0042981980.010

apip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
immune system diseaseDOID:291400.012
inherited metabolic disorderDOID:65500.011