Danio rerio

27 known processes

dkk1a

dickkopf 1a

(Aliases: si:dkeyp-86d6.1)

dkk1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular processGO:00485232830.241
generation of neuronsGO:00486993850.212
positive regulation of biological processGO:00485182530.151
cellular nitrogen compound metabolic processGO:00346412900.150
nitrogen compound metabolic processGO:00068073190.148
signal transductionGO:00071654550.146
cellular macromolecule metabolic processGO:00442603910.143
heterocycle biosynthetic processGO:00181302150.142
regulation of metabolic processGO:00192223590.134
cell migrationGO:00164772370.132
agingGO:000756820.132
digestive system developmentGO:00551232890.130
central nervous system developmentGO:00074173870.129
neuron developmentGO:00486662620.123
cellular response to radiationGO:007147840.120
organic cyclic compound metabolic processGO:19013603010.119
regulation of signalingGO:00230512350.116
tube morphogenesisGO:00352393490.113
g protein coupled receptor signaling pathwayGO:0007186740.108
regulation of cellular metabolic processGO:00313233200.105
regulation of signal transductionGO:00099662250.103
response to drugGO:004249330.102
response to chemicalGO:00422213200.100
neuron differentiationGO:00301823530.097
cellular biosynthetic processGO:00442492860.096
cellular component movementGO:00069283350.095
organonitrogen compound metabolic processGO:1901564740.089
blood vessel developmentGO:00015682460.088
regulation of nitrogen compound metabolic processGO:00511712510.088
eye developmentGO:00016542770.087
localization of cellGO:00516742440.084
positive regulation of transportGO:005105020.084
morphogenesis of an epitheliumGO:00020093330.083
heterocycle metabolic processGO:00464832900.082
regulation of cell communicationGO:00106462320.081
immune system developmentGO:00025201910.080
cell motilityGO:00488702440.076
aromatic compound biosynthetic processGO:00194382170.074
nucleobase containing compound biosynthetic processGO:00346542050.074
regulation of response to stimulusGO:00485832690.073
camera type eye morphogenesisGO:00485931080.072
rna biosynthetic processGO:00327741810.072
nucleocytoplasmic transportGO:000691340.072
digestive tract morphogenesisGO:00485462310.072
digestive tract developmentGO:00485652650.071
camera type eye developmentGO:00430102220.070
response to external stimulusGO:00096052640.070
gene expressionGO:00104672520.069
response to stressGO:00069502630.069
larval developmentGO:000216420.069
cellular aromatic compound metabolic processGO:00067252950.069
ameboidal type cell migrationGO:00016671430.068
establishment of localizationGO:00512342440.067
regulation of cellular biosynthetic processGO:00313262450.066
sensory organ developmentGO:00074233930.066
transcription dna templatedGO:00063511810.065
nucleobase containing compound metabolic processGO:00061392740.063
regulation of gene expressionGO:00104682650.063
maintenance of locationGO:005123540.063
negative regulation of protein kinase activityGO:000646940.063
cell surface receptor signaling pathwayGO:00071663250.063
immune system processGO:00023762410.062
nucleic acid templated transcriptionGO:00976591810.062
gland developmentGO:00487321430.062
phosphate containing compound metabolic processGO:00067961080.062
regulation of biological qualityGO:00650082630.061
regulation of nucleobase containing compound metabolic processGO:00192192500.061
cellular nitrogen compound biosynthetic processGO:00442712180.061
macromolecule biosynthetic processGO:00090592270.060
positive regulation of cellular processGO:00485222010.059
organic cyclic compound biosynthetic processGO:19013622230.058
system processGO:00030081850.058
vasculature developmentGO:00019442780.058
negative regulation of signal transductionGO:0009968940.057
head developmentGO:00603223030.057
blood vessel morphogenesisGO:00485142160.057
heart developmentGO:00075073130.057
phosphorus metabolic processGO:00067931090.055
organic substance biosynthetic processGO:19015762890.054
regulation of cellular amino acid metabolic processGO:000652100.054
forebrain developmentGO:0030900960.053
protein import into nucleusGO:000660630.053
negative regulation of protein phosphorylationGO:000193340.053
embryonic organ developmentGO:00485683810.052
cell projection organizationGO:00300302840.052
regulation of peptidyl tyrosine phosphorylationGO:005073010.052
sensory organ morphogenesisGO:00905962000.052
biosynthetic processGO:00090582940.051
cellular response to extracellular stimulusGO:003166820.050
determination of bilateral symmetryGO:00098552040.050
multicellular organism growthGO:003526440.050
regulation of multicellular organismal developmentGO:20000262230.049
regionalizationGO:00030022740.049
positive regulation of metabolic processGO:00098931080.049
single organism metabolic processGO:00447102170.049
regulation of nucleic acid templated transcriptionGO:19035062130.049
small molecule metabolic processGO:0044281770.048
regulation of biosynthetic processGO:00098892500.048
response to abiotic stimulusGO:00096281220.048
stem cell differentiationGO:00488631170.048
single organism transportGO:00447652060.048
oxoacid metabolic processGO:0043436310.048
regulation of cellular macromolecule biosynthetic processGO:20001122220.048
negative regulation of kinase activityGO:003367340.047
positive regulation of canonical wnt signaling pathwayGO:009026340.047
adult behaviorGO:003053420.046
positive regulation of cell cycleGO:004578730.045
cellular response to external stimulusGO:007149620.045
regulation of primary metabolic processGO:00800903110.044
response to carbohydrateGO:000974330.043
chemotaxisGO:00069351040.043
regulation of establishment of protein localizationGO:007020140.043
hematopoietic or lymphoid organ developmentGO:00485341910.043
stem cell maintenanceGO:001982740.043
carboxylic acid metabolic processGO:0019752220.042
regulation of cytoplasmic transportGO:190364940.042
cell substrate adhesionGO:003158940.042
regulation of macromolecule metabolic processGO:00602553170.042
cellular amine metabolic processGO:004410620.042
brain developmentGO:00074202930.042
convergent extensionGO:00600261180.041
positive regulation of nitrogen compound metabolic processGO:0051173690.041
negative regulation of signalingGO:0023057960.041
negative regulation of biological processGO:00485193040.041
establishment of protein localization to organelleGO:007259440.041
protein importGO:001703830.040
regulation of sequestering of calcium ionGO:005128240.040
sensory system developmentGO:0048880760.040
stem cell proliferationGO:007208940.039
axon developmentGO:00615641660.039
myeloid cell differentiationGO:0030099860.039
regulation of tube sizeGO:003515020.039
regulation of cellular amine metabolic processGO:003323800.039
cellular amino acid metabolic processGO:000652070.039
locomotionGO:00400113130.039
retina morphogenesis in camera type eyeGO:0060042790.039
regulation of rna biosynthetic processGO:20011412130.039
regulation of cytokine productionGO:000181730.039
cellular component morphogenesisGO:00329893360.038
cell morphogenesisGO:00009022890.038
cellular response to starvationGO:000926710.038
positive regulation of cellular catabolic processGO:003133130.038
cellular ketone metabolic processGO:0042180110.038
cellular response to chemical stimulusGO:00708871570.038
amine metabolic processGO:000930820.038
nuclear transportGO:005116940.038
regulation of nucleocytoplasmic transportGO:004682220.038
female sex differentiationGO:004666040.037
cell migration involved in gastrulationGO:0042074790.037
regulation of bindingGO:005109830.036
single organism localizationGO:19025782250.036
phosphorylationGO:0016310690.036
positive regulation of cytokine productionGO:000181920.035
hemopoiesisGO:00300971830.035
homeostatic processGO:00425921420.035
positive regulation of cellular metabolic processGO:0031325940.035
protein targeting to nucleusGO:004474430.035
regulation of macromolecule biosynthetic processGO:00105562250.034
somitogenesisGO:0001756870.034
response to radiationGO:0009314510.034
negative regulation of metabolic processGO:0009892860.034
cellular macromolecule biosynthetic processGO:00346452240.033
neuron projection developmentGO:00311751800.033
ear developmentGO:00435831270.033
phototransductionGO:000760220.033
single organism nuclear importGO:190259330.033
regulation of cellular ketone metabolic processGO:001056570.033
gtp metabolic processGO:004603940.033
stem cell developmentGO:0048864820.033
regulation of epithelial cell proliferationGO:005067830.032
developmental growthGO:00485891660.032
nucleic acid metabolic processGO:00903042440.032
regulation of blood vessel sizeGO:005088020.032
regulation of transcription dna templatedGO:00063552130.032
wnt signaling pathwayGO:0016055800.032
transportGO:00068102200.032
negative regulation of cell communicationGO:0010648960.032
regulation of phosphate metabolic processGO:0019220430.032
regulation of inflammatory responseGO:005072720.032
cellular protein catabolic processGO:004425740.032
modification dependent protein catabolic processGO:001994130.031
gastrulationGO:00073692080.031
ubiquitin dependent protein catabolic processGO:000651130.031
cell part morphogenesisGO:00329902460.031
skeletal system developmentGO:00015011810.031
negative regulation of mitosisGO:004583930.031
axonogenesisGO:00074091520.031
angiogenesisGO:00015251580.031
gtp catabolic processGO:000618420.031
lipid storageGO:001991510.031
eye morphogenesisGO:00485921440.031
female gonad developmentGO:000858540.031
epithelial cell differentiationGO:00308551160.031
somite developmentGO:0061053960.030
negative regulation of response to stimulusGO:00485851040.030
taxisGO:00423301090.030
regulation of cell differentiationGO:00455951420.030
cellular protein modification processGO:00064641000.030
phototransduction visible lightGO:000760320.030
mesoderm developmentGO:0007498880.030
regulation of intracellular protein transportGO:003315730.030
sensory perception of chemical stimulusGO:000760630.029
programmed cell deathGO:00125011190.029
negative regulation of developmental processGO:0051093650.029
transcription from rna polymerase ii promoterGO:0006366800.028
positive regulation of catabolic processGO:000989640.028
development of primary female sexual characteristicsGO:004654540.028
regulation of protein transportGO:005122330.028
protein localization to nucleusGO:003450430.028
negative regulation of defense responseGO:003134820.028
growthGO:00400071740.028
astrocyte differentiationGO:004870810.028
determination of left right symmetryGO:00073681790.028
stem cell divisionGO:001714510.028
retina development in camera type eyeGO:00600411460.027
regulation of nucleoside metabolic processGO:000911820.027
muscle structure developmentGO:00610611960.027
embryonic cranial skeleton morphogenesisGO:0048701900.027
rna metabolic processGO:00160702190.027
axon ensheathment in central nervous systemGO:003229120.027
regulation of apoptotic processGO:0042981980.027
positive regulation of cellular component biogenesisGO:004408930.027
intracellular signal transductionGO:0035556850.026
sequestering of calcium ionGO:005120830.026
regulation of nucleotide catabolic processGO:003081120.026
regulation of locomotionGO:0040012550.026
regulation of anatomical structure morphogenesisGO:00226031300.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
cellular response to light stimulusGO:007148240.026
cellular response to nutrient levelsGO:003166920.026
anterior posterior pattern specificationGO:00099521520.026
response to light stimulusGO:0009416460.026
positive regulation of response to stimulusGO:0048584800.025
embryonic organ morphogenesisGO:00485622740.025
guanosine containing compound catabolic processGO:190106920.025
regulation of phosphorus metabolic processGO:0051174430.025
apoptotic processGO:00069151160.025
organic acid metabolic processGO:0006082310.025
response to woundingGO:00096111160.025
macromolecule modificationGO:00434121110.025
cell morphogenesis involved in differentiationGO:00009041950.024
extrinsic apoptotic signaling pathwayGO:009719130.024
regulation of protein catabolic processGO:004217610.024
cell projection morphogenesisGO:00488582440.024
inner ear developmentGO:00488391260.024
modification dependent macromolecule catabolic processGO:004363230.024
regulation of rna metabolic processGO:00512522240.024
autophagyGO:000691440.024
regulation of autophagyGO:001050630.024
protein secretionGO:000930610.024
lateral line system developmentGO:0048925760.023
neuron projection morphogenesisGO:00488121610.023
regulation of molecular functionGO:0065009700.023
regulation of transcription from rna polymerase ii promoterGO:00063571140.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.023
guanosine containing compound metabolic processGO:190106840.023
regulation of catalytic activityGO:0050790550.023
cognitionGO:005089010.023
protein polymerizationGO:005125840.023
positive regulation of secretion by cellGO:190353210.023
positive regulation of epithelial cell differentiationGO:003085820.023
protein metabolic processGO:00195381830.023
phagocytosisGO:000690930.023
positive regulation of cellular biosynthetic processGO:0031328680.023
organelle organizationGO:00069962270.022
regulation of protein bindingGO:004339330.022
regulation of protein import into nucleusGO:004230620.022
cellular response to oxygen levelsGO:007145310.022
sequestering of metal ionGO:005123830.022
negative regulation of multicellular organismal processGO:0051241690.022
cellular component maintenanceGO:004395430.022
regulation of developmental processGO:00507932470.022
nuclear importGO:005117030.022
regulation of multicellular organism growthGO:004001440.022
organelle fusionGO:004828430.022
cytokinesisGO:000091030.022
negative regulation of map kinase activityGO:004340720.022
cell proliferationGO:0008283800.022
ion transportGO:00068111140.021
adherens junction organizationGO:003433240.021
behaviorGO:0007610740.021
positive regulation of macromolecule metabolic processGO:0010604930.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.021
cellular response to stressGO:0033554620.021
regulation of cell substrate adhesionGO:001081010.021
positive regulation of epithelial cell proliferationGO:005067910.021
regulation of protein targetingGO:190353320.021
hepaticobiliary system developmentGO:0061008980.021
proteasomal protein catabolic processGO:001049820.021
gastrulation with mouth forming secondGO:0001702440.021
photoreceptor cell differentiationGO:0046530550.021
calcium ion transport into cytosolGO:006040230.021
mitochondrion organizationGO:000700540.021
regulation of reactive oxygen species metabolic processGO:200037720.020
connective tissue developmentGO:0061448990.020
positive regulation of nucleobase containing compound metabolic processGO:0045935690.020
i kappab kinase nf kappab signalingGO:000724940.020
regulation of gtp catabolic processGO:003312420.020
protein modification processGO:00362111000.020
deathGO:00162651210.020
regulation of neuron differentiationGO:0045664560.020
establishment of localization in cellGO:0051649770.019
mesenchyme developmentGO:00604851270.019
smoothened signaling pathwayGO:0007224300.019
negative regulation of epithelial cell proliferationGO:005068010.019
response to nutrientGO:000758430.019
transmembrane transportGO:00550851200.019
post embryonic organ developmentGO:004856940.019
multicellular organismal homeostasisGO:0048871290.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
regulation of wnt signaling pathwayGO:0030111530.019
chordate embryonic developmentGO:00430092710.019
developmental growth involved in morphogenesisGO:0060560860.019
purine nucleotide biosynthetic processGO:0006164200.019
response to corticosteroidGO:003196010.019
chemosensory behaviorGO:000763510.019
regulation of stem cell differentiationGO:200073640.019
response to amino acidGO:004320020.019
organic substance transportGO:0071702580.019
regulation of cell shapeGO:000836010.019
positive regulation of cell communicationGO:0010647560.019
regulation of neurogenesisGO:0050767870.019
neuron projection guidanceGO:0097485860.019
nucleoside phosphate biosynthetic processGO:1901293210.019
regulation of smoothened signaling pathwayGO:0008589180.019
regulation of cellular response to growth factor stimulusGO:0090287350.019
mesenchymal cell developmentGO:0014031780.019
neurological system processGO:0050877620.019
regulation of metal ion transportGO:001095940.019
cell matrix adhesionGO:000716040.018
cell deathGO:00082191210.018
membrane invaginationGO:001032410.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
cellular lipid catabolic processGO:004424230.018
negative regulation of stem cell differentiationGO:200073720.018
lipid catabolic processGO:001604240.018
nuclear migrationGO:000709730.018
neuroblast proliferationGO:000740520.018
negative regulation of protein serine threonine kinase activityGO:007190120.018
regulation of protein complex assemblyGO:004325430.018
gliogenesisGO:0042063450.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
negative regulation of mapk cascadeGO:004340940.018
defense responseGO:0006952470.018
negative regulation of apoptotic processGO:0043066550.018
response to external biotic stimulusGO:0043207970.018
neuron neuron synaptic transmissionGO:000727010.018
regulation of cell deathGO:00109411030.018
negative regulation of macromolecule metabolic processGO:0010605760.018
developmental programmed cell deathGO:001062340.018
positive regulation of biosynthetic processGO:0009891680.018
positive regulation of cellular amine metabolic processGO:003324000.017
synaptic growth at neuromuscular junctionGO:005112420.017
regulation of multicellular organismal processGO:00512392770.017
cell growthGO:0016049570.017
endoderm developmentGO:0007492490.017
response to organic substanceGO:00100331530.017
notochord developmentGO:0030903540.017
ectodermal placode developmentGO:0071696370.017
dorsal ventral pattern formationGO:00099531250.017
embryonic skeletal system morphogenesisGO:0048704930.017
regulation of programmed cell deathGO:00430671010.017
response to glucocorticoidGO:005138410.017
regulation of synaptic plasticityGO:004816710.017
inner ear morphogenesisGO:0042472630.017
muscle cell developmentGO:00550011150.017
fertilizationGO:000956630.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
embryonic heart tube morphogenesisGO:00031431080.016
locomotory behaviorGO:0007626340.016
regulation of embryonic developmentGO:0045995470.016
response to other organismGO:0051707970.016
erythrocyte developmentGO:0048821240.016
lateral line developmentGO:0048882660.016
tissue regenerationGO:0042246740.016
cellular response to hypoxiaGO:007145610.016
neural crest cell differentiationGO:0014033720.016
sleepGO:003043110.016
negative regulation of sequestering of calcium ionGO:005128340.016
protein stabilizationGO:005082120.016
regulation of cell activationGO:005086510.016
production of molecular mediator of immune responseGO:000244020.016
striated muscle cell differentiationGO:00511461290.016
cellular response to decreased oxygen levelsGO:003629410.016
axon guidanceGO:0007411860.016
heart loopingGO:0001947940.016
negative regulation of catabolic processGO:000989530.016
positive regulation of gene expressionGO:0010628710.016
carbohydrate homeostasisGO:003350010.016
heart morphogenesisGO:00030071560.016
regulation of protein localization to nucleusGO:190018020.016
single organism organelle organizationGO:19025891990.016
regulation of dendrite developmentGO:005077330.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
cellular localizationGO:0051641970.015
response to hypoxiaGO:0001666250.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
neural tube developmentGO:0021915620.015
g1 s transition of mitotic cell cycleGO:000008210.015
reactive oxygen species biosynthetic processGO:190340910.015
single organism membrane fusionGO:004480120.015
cell cycle g1 s phase transitionGO:004484310.015
regulation of organ growthGO:004662030.015
positive regulation of signalingGO:0023056560.015
cartilage developmentGO:0051216960.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
vasculogenesisGO:0001570410.015
tube closureGO:006060610.015
positive regulation of cell divisionGO:005178120.015
cellular response to organic substanceGO:00713101050.015
embryonic pattern specificationGO:0009880440.015
negative regulation of secretion by cellGO:190353120.015
single fertilizationGO:000733830.015
small molecule catabolic processGO:004428230.015
regulation of protein polymerizationGO:003227120.015
photoreceptor cell outer segment organizationGO:003584590.015
b cell activationGO:004211320.015
regulation of cell motilityGO:2000145460.015
regulation of cellular component movementGO:0051270550.015
regulation of dendrite morphogenesisGO:004881430.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
regulation of nervous system developmentGO:0051960900.015
response to biotic stimulusGO:0009607970.015
response to endogenous stimulusGO:0009719830.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
cellular component disassemblyGO:002241110.014
regulation of cellular component organizationGO:0051128860.014
single organism biosynthetic processGO:0044711710.014
negative regulation of cell differentiationGO:0045596460.014
liver developmentGO:0001889960.014
cell fate commitmentGO:0045165990.014
odontogenesis of dentin containing toothGO:004247510.014
positive regulation of cytoskeleton organizationGO:005149530.014
response to uvGO:000941130.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.014
positive regulation of cell adhesionGO:004578510.014
regulation of production of molecular mediator of immune responseGO:000270010.014
specification of symmetryGO:00097992040.014
macromolecule localizationGO:0033036540.014
mitotic dna integrity checkpointGO:004477440.014
mesenchymal cell differentiationGO:0048762870.014
morphogenesis of embryonic epitheliumGO:0016331300.014
apoptotic process involved in developmentGO:190274220.014
segmentationGO:0035282970.014
embryonic limb morphogenesisGO:003032620.014
positive regulation of transcription dna templatedGO:0045893570.014
cortical actin cytoskeleton organizationGO:003086610.014
regulation of cellular protein metabolic processGO:0032268520.014
renal system developmentGO:0072001940.014
actin polymerization or depolymerizationGO:000815420.014
skeletal system morphogenesisGO:00487051020.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
protein complex disassemblyGO:004324110.014
wound healingGO:0042060900.014
regenerationGO:0031099910.014
negative regulation of nuclear divisionGO:005178430.014
leukocyte proliferationGO:007066110.013
positive regulation of secretionGO:005104710.013
determination of heart left right asymmetryGO:00613711170.013
negative regulation of cellular metabolic processGO:0031324770.013
regulation of cellular protein catabolic processGO:190336210.013
small gtpase mediated signal transductionGO:000726480.013
canonical wnt signaling pathwayGO:0060070480.013
positive regulation of signal transductionGO:0009967560.013
multicellular organismal signalingGO:0035637220.013
regulation of synapse assemblyGO:005196330.013
embryonic heart tube developmentGO:00350501330.013
regulation of erk1 and erk2 cascadeGO:007037240.013
neurotransmitter transportGO:000683620.013
phagocytosis engulfmentGO:000691110.013
embryonic viscerocranium morphogenesisGO:0048703520.013
regulation of intracellular signal transductionGO:1902531570.013
cell cycleGO:0007049930.013
positive regulation of nucleotide catabolic processGO:003081310.013
primary neural tube formationGO:001402010.013
inositol lipid mediated signalingGO:004801720.013
regulation of cysteine type endopeptidase activityGO:2000116210.013
transmission of nerve impulseGO:0019226190.013
rhodopsin mediated signaling pathwayGO:001605610.013
response to vitaminGO:003327330.013
regulation of peptidase activityGO:0052547230.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of cardiac muscle tissue developmentGO:005502410.013
action potentialGO:0001508190.013
ectodermal placode morphogenesisGO:0071697320.012
cation transportGO:0006812810.012
myeloid cell homeostasisGO:0002262560.012
membrane fusionGO:006102520.012

dkk1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.139
nervous system diseaseDOID:86300.050
sensory system diseaseDOID:005015500.029
eye and adnexa diseaseDOID:149200.029
retinal diseaseDOID:567900.027
eye diseaseDOID:561400.027
retinal degenerationDOID:846600.019
musculoskeletal system diseaseDOID:1700.016
immune system diseaseDOID:291400.013