Danio rerio

57 known processes

inpp5e

inositol polyphosphate-5-phosphatase

(Aliases: Innpp5e,im:7152772,zgc:165612)

inpp5e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.089
agingGO:000756820.073
negative regulation of cellular processGO:00485232830.059
embryonic organ developmentGO:00485683810.055
morphogenesis of an epitheliumGO:00020093330.054
signal transductionGO:00071654550.052
sensory organ developmentGO:00074233930.048
regulation of establishment of protein localizationGO:007020140.046
positive regulation of transportGO:005105020.046
tube morphogenesisGO:00352393490.046
cellular macromolecule metabolic processGO:00442603910.045
negative regulation of biological processGO:00485193040.045
embryonic organ morphogenesisGO:00485622740.044
cellular component movementGO:00069283350.044
cellular response to external stimulusGO:007149620.044
cellular nitrogen compound metabolic processGO:00346412900.044
regulation of protein transportGO:005122330.044
nitrogen compound metabolic processGO:00068073190.043
cognitionGO:005089010.043
nuclear transportGO:005116940.041
multicellular organism growthGO:003526440.041
response to chemicalGO:00422213200.039
nucleocytoplasmic transportGO:000691340.039
cell migrationGO:00164772370.039
gene expressionGO:00104672520.038
cell substrate adhesionGO:003158940.037
regulation of intracellular protein transportGO:003315730.037
organic cyclic compound metabolic processGO:19013603010.037
positive regulation of cell cycleGO:004578730.036
establishment of protein localization to organelleGO:007259440.036
regulation of macromolecule metabolic processGO:00602553170.035
cellular nitrogen compound biosynthetic processGO:00442712180.035
maintenance of locationGO:005123540.035
phagocytosisGO:000690930.035
guanosine containing compound catabolic processGO:190106920.034
transportGO:00068102200.034
regulation of cytoplasmic transportGO:190364940.034
heart developmentGO:00075073130.034
regulation of multicellular organism growthGO:004001440.033
locomotionGO:00400113130.033
heterocycle metabolic processGO:00464832900.033
cellular protein catabolic processGO:004425740.033
regulation of protein complex assemblyGO:004325430.033
generation of neuronsGO:00486993850.033
cell morphogenesisGO:00009022890.033
nucleic acid metabolic processGO:00903042440.033
guanosine containing compound metabolic processGO:190106840.033
regulation of nitrogen compound metabolic processGO:00511712510.033
protein targeting to nucleusGO:004474430.032
regulation of primary metabolic processGO:00800903110.032
biosynthetic processGO:00090582940.032
cellular response to extracellular stimulusGO:003166820.032
cytokinesisGO:000091030.031
cellular biosynthetic processGO:00442492860.031
response to nutrientGO:000758430.031
organic substance biosynthetic processGO:19015762890.031
eye developmentGO:00016542770.031
stem cell proliferationGO:007208940.031
positive regulation of catabolic processGO:000989640.031
regulation of metal ion transportGO:001095940.030
gtp catabolic processGO:000618420.030
regulation of nucleocytoplasmic transportGO:004682220.030
protein localization to nucleusGO:003450430.030
cellular response to nutrient levelsGO:003166920.030
nuclear importGO:005117030.030
single organism nuclear importGO:190259330.030
nucleobase containing compound metabolic processGO:00061392740.030
gtp metabolic processGO:004603940.030
cell motilityGO:00488702440.029
stem cell maintenanceGO:001982740.029
peptidyl serine phosphorylationGO:001810510.029
mitochondrion organizationGO:000700540.029
transcription dna templatedGO:00063511810.029
cellular component morphogenesisGO:00329893360.029
regulation of bindingGO:005109830.029
regulation of protein targetingGO:190353320.029
digestive tract developmentGO:00485652650.029
autophagyGO:000691440.028
negative regulation of protein phosphorylationGO:000193340.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
regulation of neural precursor cell proliferationGO:200017730.028
digestive system developmentGO:00551232890.028
chordate embryonic developmentGO:00430092710.028
regulation of protein import into nucleusGO:004230620.028
positive regulation of cellular catabolic processGO:003133130.027
cellular response to starvationGO:000926710.027
amine metabolic processGO:000930820.027
regulation of protein localization to nucleusGO:190018020.027
peptidyl serine modificationGO:001820920.027
regulation of cellular metabolic processGO:00313233200.027
cellular aromatic compound metabolic processGO:00067252950.027
positive regulation of cellular component biogenesisGO:004408930.027
regulation of cellular biosynthetic processGO:00313262450.027
organonitrogen compound metabolic processGO:1901564740.027
small molecule metabolic processGO:0044281770.027
system processGO:00030081850.027
response to carbohydrateGO:000974330.027
head developmentGO:00603223030.027
regulation of synaptic plasticityGO:004816710.026
regulation of developmental processGO:00507932470.026
response to drugGO:004249330.026
modification dependent macromolecule catabolic processGO:004363230.026
extrinsic apoptotic signaling pathwayGO:009719130.026
regulation of nucleobase containing compound metabolic processGO:00192192500.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
negative regulation of protein kinase activityGO:000646940.026
cell projection morphogenesisGO:00488582440.026
organelle fusionGO:004828430.026
regulation of protein catabolic processGO:004217610.026
regulation of synapse assemblyGO:005196330.026
single organism localizationGO:19025782250.026
regulation of nucleoside metabolic processGO:000911820.026
regulation of biosynthetic processGO:00098892500.025
cellular response to oxygen levelsGO:007145310.025
protein importGO:001703830.025
vasculature developmentGO:00019442780.025
muscle structure developmentGO:00610611960.025
neuroblast proliferationGO:000740520.025
neuron differentiationGO:00301823530.025
lipid catabolic processGO:001604240.025
camera type eye developmentGO:00430102220.025
single organism transportGO:00447652060.025
rna metabolic processGO:00160702190.025
cell projection organizationGO:00300302840.024
membrane fusionGO:006102520.024
cellular macromolecule biosynthetic processGO:00346452240.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
negative regulation of kinase activityGO:003367340.024
neuron neuron synaptic transmissionGO:000727010.024
regulation of cell shapeGO:000836010.024
single organism membrane fusionGO:004480120.024
regulation of cellular amine metabolic processGO:003323800.024
regulation of metabolic processGO:00192223590.024
oxoacid metabolic processGO:0043436310.023
digestive tract morphogenesisGO:00485462310.023
central nervous system developmentGO:00074173870.023
localization of cellGO:00516742440.023
establishment of localizationGO:00512342440.023
modification dependent protein catabolic processGO:001994130.023
adult behaviorGO:003053420.023
ubiquitin dependent protein catabolic processGO:000651130.023
proteasomal protein catabolic processGO:001049820.023
heterocycle biosynthetic processGO:00181302150.023
cellular carbohydrate metabolic processGO:004426240.023
cellular component assemblyGO:00226071700.023
single organism organelle organizationGO:19025891990.023
regulation of cytokine productionGO:000181730.023
regulation of cellular amino acid metabolic processGO:000652100.022
positive regulation of biological processGO:00485182530.022
protein import into nucleusGO:000660630.022
exocytosisGO:000688710.022
organic cyclic compound biosynthetic processGO:19013622230.022
protein metabolic processGO:00195381830.022
regulation of stem cell proliferationGO:007209120.022
protein localization to plasma membraneGO:007265910.022
establishment of synaptic vesicle localizationGO:009748010.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
macromolecule biosynthetic processGO:00090592270.022
regulation of synapse organizationGO:005080730.021
sensory organ morphogenesisGO:00905962000.021
negative regulation of cytoplasmic transportGO:190365020.021
regulation of signal transductionGO:00099662250.021
cellular component biogenesisGO:00440851780.021
single organism metabolic processGO:00447102170.021
apoptotic processGO:00069151160.021
cellular amine metabolic processGO:004410620.021
regulation of macromolecule biosynthetic processGO:00105562250.021
rna biosynthetic processGO:00327741810.021
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.021
lipid storageGO:001991510.021
synaptic growth at neuromuscular junctionGO:005112420.021
response to monosaccharideGO:003428430.021
regulation of cellular ketone metabolic processGO:001056570.021
synaptic vesicle localizationGO:009747910.021
organic acid metabolic processGO:0006082310.020
carboxylic acid metabolic processGO:0019752220.020
regulation of multicellular organismal processGO:00512392770.020
cell matrix adhesionGO:000716040.020
negative regulation of protein transportGO:005122430.020
response to uvGO:000941130.020
regulation of mrna processingGO:005068430.020
aromatic compound biosynthetic processGO:00194382170.020
organelle organizationGO:00069962270.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
meiotic nuclear divisionGO:000712640.020
blood vessel developmentGO:00015682460.020
regulation of autophagyGO:001050630.020
cell part morphogenesisGO:00329902460.020
ameboidal type cell migrationGO:00016671430.020
endosomal transportGO:001619720.020
regulation of gene expressionGO:00104682650.020
atp catabolic processGO:000620040.020
deathGO:00162651210.020
response to external stimulusGO:00096052640.020
cell surface receptor signaling pathwayGO:00071663250.020
regulation of nucleotide catabolic processGO:003081120.019
programmed cell deathGO:00125011190.019
cilium morphogenesisGO:0060271850.019
nucleobase containing compound biosynthetic processGO:00346542050.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
fertilizationGO:000956630.019
regulation of reactive oxygen species metabolic processGO:200037720.019
i kappab kinase nf kappab signalingGO:000724940.019
glucose homeostasisGO:004259310.019
response to corticosteroidGO:003196010.019
meiotic cell cycle processGO:190304630.019
embryo development ending in birth or egg hatchingGO:00097922710.019
regulation of transcription dna templatedGO:00063552130.019
somatic muscle developmentGO:000752540.019
response to glucocorticoidGO:005138410.019
regulation of cell activationGO:005086510.019
regulation of rna metabolic processGO:00512522240.019
cilium organizationGO:0044782710.019
cell deathGO:00082191210.019
regulation of apoptotic processGO:0042981980.019
cilium assemblyGO:0042384580.019
immune system processGO:00023762410.019
neurological system processGO:0050877620.019
neuron developmentGO:00486662620.018
response to stressGO:00069502630.018
regulation of programmed cell deathGO:00430671010.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
positive regulation of secretion by cellGO:190353210.018
cellular response to chemical stimulusGO:00708871570.018
response to organic substanceGO:00100331530.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
positive regulation of secretionGO:005104710.018
cellular response to radiationGO:007147840.018
neurotransmitter transportGO:000683620.018
nucleic acid templated transcriptionGO:00976591810.018
brain developmentGO:00074202930.018
regulation of response to stimulusGO:00485832690.018
response to hexoseGO:000974630.018
cellular response to hypoxiaGO:007145610.018
regulation of cell substrate adhesionGO:001081010.018
positive regulation of cytokine productionGO:000181920.018
compound eye developmentGO:004874920.018
regulation of wound healingGO:006104120.018
positive regulation of cell adhesionGO:004578510.018
negative regulation of intracellular transportGO:003238730.018
synaptic vesicle transportGO:004848910.018
golgi vesicle transportGO:004819330.018
carbohydrate homeostasisGO:003350010.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of biological qualityGO:00650082630.017
centrosome organizationGO:005129710.017
stem cell divisionGO:001714510.017
rna localizationGO:000640340.017
heart morphogenesisGO:00030071560.017
cellular component disassemblyGO:002241110.017
regulation of signalingGO:00230512350.017
embryonic heart tube developmentGO:00350501330.017
cellular ketone metabolic processGO:0042180110.017
adherens junction organizationGO:003433240.017
gastrulationGO:00073692080.017
purine nucleoside monophosphate catabolic processGO:000912840.017
regulation of reproductive processGO:200024140.017
regulation of protein bindingGO:004339330.017
spermatid differentiationGO:004851520.017
regulation of gtp catabolic processGO:003312420.016
organelle assemblyGO:00709251100.016
secondary metabolic processGO:001974830.016
protein dephosphorylationGO:000647030.016
microtubule organizing center organizationGO:003102310.016
cellular amide metabolic processGO:004360340.016
locomotor rhythmGO:004547530.016
regulation of cell communicationGO:00106462320.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
regionalizationGO:00030022740.016
macroautophagyGO:001623610.016
mitotic dna integrity checkpointGO:004477440.016
nuclear exportGO:005116810.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of cytoskeleton organizationGO:005149530.016
spermatid developmentGO:000728620.016
homeostatic processGO:00425921420.016
neurotransmitter secretionGO:000726920.016
embryonic skeletal system developmentGO:0048706970.016
angiogenesisGO:00015251580.016
cellular amino acid metabolic processGO:000652070.016
cellular protein metabolic processGO:00442671290.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
developmental growthGO:00485891660.016
establishment of protein localization to plasma membraneGO:009000210.016
intracellular signal transductionGO:0035556850.016
sequestering of calcium ionGO:005120830.016
alcohol biosynthetic processGO:004616520.015
positive regulation of cellular processGO:00485222010.015
regulation of multicellular organismal developmentGO:20000262230.015
regulation of sequestering of calcium ionGO:005128240.015
regulation of calcium ion transportGO:005192420.015
regulation of rna biosynthetic processGO:20011412130.015
response to alkaloidGO:004327920.015
blood vessel morphogenesisGO:00485142160.015
retina development in camera type eyeGO:00600411460.015
peptide transportGO:001583310.015
hemopoiesisGO:00300971830.015
determination of bilateral symmetryGO:00098552040.015
startle responseGO:000196440.015
single fertilizationGO:000733830.015
negative regulation of intracellular protein transportGO:009031730.015
cellular response to decreased oxygen levelsGO:003629410.015
sensory perception of painGO:001923310.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
positive regulation of nucleoside metabolic processGO:004597910.015
nucleoside monophosphate catabolic processGO:000912540.015
regulation of dna replicationGO:000627530.015
actin filament based movementGO:003004810.015
leukocyte proliferationGO:007066110.015
determination of left right symmetryGO:00073681790.015
regulation of dendrite developmentGO:005077330.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
sleepGO:003043110.014
protein modification processGO:00362111000.014
skeletal system morphogenesisGO:00487051020.014
regulation of meiotic cell cycleGO:005144510.014
negative regulation of catabolic processGO:000989530.014
skeletal system developmentGO:00015011810.014
response to abiotic stimulusGO:00096281220.014
pigmentationGO:0043473850.014
cellular response to light stimulusGO:007148240.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
phototransductionGO:000760220.014
regulation of protein ubiquitinationGO:003139630.014
epithelial tube morphogenesisGO:00605621480.014
phagocytosis engulfmentGO:000691110.014
regulation of cell deathGO:00109411030.014
growthGO:00400071740.014
membrane invaginationGO:001032410.014
actin polymerization or depolymerizationGO:000815420.014
regulation of cell differentiationGO:00455951420.014
muscle cell differentiationGO:00426921390.014
cell morphogenesis involved in differentiationGO:00009041950.014
cellular pigmentationGO:0033059300.014
peptide metabolic processGO:000651810.014
positive regulation of nucleotide catabolic processGO:003081310.014
cellular protein modification processGO:00064641000.014
carboxylic acid catabolic processGO:004639530.014
positive regulation of cell activationGO:005086710.014
transmembrane transportGO:00550851200.014
chemosensory behaviorGO:000763510.014
germ line stem cell maintenanceGO:003071820.014
regulation of gtpase activityGO:004308720.014
phosphorus metabolic processGO:00067931090.013
positive regulation of protein complex assemblyGO:003133420.013
signal transduction in absence of ligandGO:003803410.013
meiotic chromosome segregationGO:004513230.013
gland developmentGO:00487321430.013
liver developmentGO:0001889960.013
immune system developmentGO:00025201910.013
positive regulation of cellular amine metabolic processGO:003324000.013
protein complex disassemblyGO:004324110.013
sequestering of metal ionGO:005123830.013
transcription from rna polymerase ii promoterGO:0006366800.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
positive regulation of gtpase activityGO:004354710.013
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.013
macromolecular complex disassemblyGO:003298410.013
regulation of inflammatory responseGO:005072720.013
cell cycle g1 s phase transitionGO:004484310.013
ear developmentGO:00435831270.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
somatic stem cell maintenanceGO:003501910.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
convergent extensionGO:00600261180.013
eye morphogenesisGO:00485921440.013
regulation of carbohydrate metabolic processGO:000610940.013
regulation of response to nutrient levelsGO:003210710.013
regulation of muscle contractionGO:000693730.013
regulation of transmembrane transporter activityGO:002289820.013
multi organism processGO:00517041340.013
er nucleus signaling pathwayGO:000698420.013
response to hydrogen peroxideGO:004254230.013
negative regulation of sequestering of calcium ionGO:005128340.013
regulation of erk1 and erk2 cascadeGO:007037240.013
cytoskeleton organizationGO:0007010960.013
myeloid cell differentiationGO:0030099860.013
response to topologically incorrect proteinGO:003596620.013
mitochondrial transportGO:000683920.013
hormone secretionGO:004687920.013
camera type eye morphogenesisGO:00485931080.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
striated muscle tissue developmentGO:00147061100.013
regulation of epithelial cell proliferationGO:005067830.012
ion transportGO:00068111140.012
regulation of cellular protein catabolic processGO:190336210.012
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of macromolecule metabolic processGO:0010605760.012
negative regulation of response to stimulusGO:00485851040.012
translational initiationGO:000641330.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
regulation of transporter activityGO:003240920.012
fatty acid catabolic processGO:000906210.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
negative regulation of metabolic processGO:0009892860.012
protein polymerizationGO:005125840.012
positive regulation of gtp catabolic processGO:003312610.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
establishment of vesicle localizationGO:0051650240.012
developmental programmed cell deathGO:001062340.012
small molecule catabolic processGO:004428230.012
regulation of jak stat cascadeGO:004642530.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
muscle cell developmentGO:00550011150.012
specification of symmetryGO:00097992040.012
macromolecule modificationGO:00434121110.012
centrosome cycleGO:000709810.012
phosphate containing compound metabolic processGO:00067961080.012
regulation of dendrite morphogenesisGO:004881430.012
regulation of ion transmembrane transporter activityGO:003241220.012
retina morphogenesis in camera type eyeGO:0060042790.012
cellular localizationGO:0051641970.012
striated muscle cell developmentGO:00550021080.012
response to endogenous stimulusGO:0009719830.012
positive regulation of dna metabolic processGO:005105410.012
negative regulation of defense responseGO:003134820.012
response to glucoseGO:000974930.012
regulation of protein polymerizationGO:003227120.012
regulation of stem cell differentiationGO:200073640.012
regulation of exocytosisGO:001715710.012
embryonic heart tube morphogenesisGO:00031431080.012
establishment of localization in cellGO:0051649770.012
cytoskeleton dependent cytokinesisGO:006164030.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
regulation of cellular component organizationGO:0051128860.012
xenobiotic metabolic processGO:000680540.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of circadian rhythmGO:004275240.012
muscle tissue developmentGO:00605371100.012
regulation of response to extracellular stimulusGO:003210410.012
female sex differentiationGO:004666040.012
post embryonic organ developmentGO:004856940.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
negative regulation of mapk cascadeGO:004340940.011
pigment granule localizationGO:0051875250.011
striated muscle cell differentiationGO:00511461290.011
cellular response to reactive oxygen speciesGO:003461420.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
cellular component assembly involved in morphogenesisGO:00109271070.011
embryonic skeletal system morphogenesisGO:0048704930.011
organism emergence from protective structureGO:007168440.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cell cycleGO:0007049930.011
cellular response to organic substanceGO:00713101050.011
cell projection assemblyGO:0030031640.011
female gonad developmentGO:000858540.011
protein secretionGO:000930610.011
neuron projection morphogenesisGO:00488121610.011
tissue remodelingGO:004877140.011
negative regulation of protein localization to nucleusGO:190018120.011
nuclear migrationGO:000709730.011
tyrosine phosphorylation of stat proteinGO:000726010.011
negative regulation of protein import into nucleusGO:004230820.011
negative regulation of synapse assemblyGO:005196420.011
interspecies interaction between organismsGO:004441940.011
neuron projection developmentGO:00311751800.011
protein homooligomerizationGO:005126030.011
lymphocyte proliferationGO:004665110.011
regulation of blood pressureGO:000821710.011
epithelial cell differentiationGO:00308551160.011
hepaticobiliary system developmentGO:0061008980.011
erk1 and erk2 cascadeGO:007037140.011
tube closureGO:006060610.011
regulation of localizationGO:00328791040.011
carbohydrate biosynthetic processGO:001605110.011
blood circulationGO:0008015870.011
pancreas developmentGO:0031016840.011
peptidyl threonine modificationGO:001821010.011
determination of heart left right asymmetryGO:00613711170.011
ras protein signal transductionGO:000726570.011
urogenital system developmentGO:0001655970.011
peptidyl threonine phosphorylationGO:001810710.011
production of molecular mediator of immune responseGO:000244020.011
negative regulation of cellular catabolic processGO:003133030.011
nucleic acid transportGO:005065720.011
oocyte anterior posterior axis specificationGO:000731440.011
organic acid catabolic processGO:001605430.011
protein acetylationGO:000647320.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
response to radiationGO:0009314510.011
development of primary female sexual characteristicsGO:004654540.011
response to other organismGO:0051707970.010
cytoplasm organizationGO:000702840.010
mononuclear cell proliferationGO:003294310.010

inpp5e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.070
nervous system diseaseDOID:86300.028
cardiovascular system diseaseDOID:128700.024
musculoskeletal system diseaseDOID:1700.020
organ system cancerDOID:005068600.017
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
disease of metabolismDOID:001466700.015
muscular diseaseDOID:008000000.013
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011