Danio rerio

0 known processes

kdm4b

lysine (K)-specific demethylase 4B

(Aliases: jmjd2b,si:ch211-124a3.4)

kdm4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein demethylationGO:000648220.458
Yeast Fly
histone demethylationGO:001657720.351
Yeast Fly
larval developmentGO:000216420.282
locomotionGO:00400113130.214
cognitionGO:005089010.190
histone lysine demethylationGO:007007620.132
Yeast Fly
sensory perception of touchGO:005097520.115
cellular biosynthetic processGO:00442492860.114
Yeast
regulation of macromolecule biosynthetic processGO:00105562250.108
Yeast
chordate embryonic developmentGO:00430092710.098
brain developmentGO:00074202930.085
circadian sleep wake cycle processGO:002241020.084
histone h3 k9 demethylationGO:003316920.081
Yeast Fly
detection of mechanical stimulus involved in sensory perception of touchGO:005097620.079
cellular amide metabolic processGO:004360340.075
head developmentGO:00603223030.074
heterocycle metabolic processGO:00464832900.073
Yeast
circadian sleep wake cycleGO:004274520.072
heterocycle biosynthetic processGO:00181302150.071
Yeast
regulation of synapse organizationGO:005080730.071
protein dealkylationGO:000821420.067
Yeast Fly
biosynthetic processGO:00090582940.066
Yeast
striated muscle cell developmentGO:00550021080.064
neuron projection developmentGO:00311751800.064
central nervous system developmentGO:00074173870.062
chemotaxisGO:00069351040.062
regionalizationGO:00030022740.061
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.061
regulation of multicellular organismal developmentGO:20000262230.061
stem cell maintenanceGO:001982740.061
rna biosynthetic processGO:00327741810.059
Yeast
regulation of stem cell differentiationGO:200073640.059
cell part morphogenesisGO:00329902460.056
negative regulation of signal transductionGO:0009968940.056
maintenance of locationGO:005123540.054
cellular nitrogen compound metabolic processGO:00346412900.054
Yeast
cell morphogenesisGO:00009022890.053
striated muscle tissue developmentGO:00147061100.053
circadian sleep wake cycle sleepGO:005080210.053
nucleic acid metabolic processGO:00903042440.053
Yeast
cellular nitrogen compound biosynthetic processGO:00442712180.052
Yeast
synaptic target recognitionGO:000803910.048
macromolecule modificationGO:00434121110.048
Yeast Fly
response to drugGO:004249330.047
regulation of gene expressionGO:00104682650.044
Yeast Fly
electron transport chainGO:002290020.044
positive regulation of erk1 and erk2 cascadeGO:007037420.044
cell morphogenesis involved in differentiationGO:00009041950.044
positive regulation of stem cell proliferationGO:200064810.044
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.044
negative regulation of multicellular organismal processGO:0051241690.044
regulation of response to stimulusGO:00485832690.043
specification of organ identityGO:001009220.042
regulation of cell matrix adhesionGO:000195210.041
regulation of biological qualityGO:00650082630.041
Yeast
chromatin organizationGO:0006325220.041
Yeast Fly
cellular response to chemical stimulusGO:00708871570.041
positive regulation of neural precursor cell proliferationGO:200017910.041
regulation of synapse assemblyGO:005196330.041
hormone transportGO:000991420.041
organic cyclic compound metabolic processGO:19013603010.041
Yeast
agingGO:000756820.040
Yeast
protein import into nucleusGO:000660630.040
regulation of bindingGO:005109830.039
tube morphogenesisGO:00352393490.039
convergent extensionGO:00600261180.039
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.039
signal transductionGO:00071654550.038
positive regulation of cellular processGO:00485222010.037
Yeast
localization of cellGO:00516742440.037
atp synthesis coupled electron transportGO:004277310.037
axonogenesisGO:00074091520.036
neuron projection morphogenesisGO:00488121610.036
negative regulation of biological processGO:00485193040.035
Yeast
peptide metabolic processGO:000651810.035
regulation of erk1 and erk2 cascadeGO:007037240.035
morphogenesis of an epitheliumGO:00020093330.034
establishment of synaptic vesicle localizationGO:009748010.034
muscle cell developmentGO:00550011150.034
generation of neuronsGO:00486993850.034
neurotransmitter transportGO:000683620.034
cell projection morphogenesisGO:00488582440.033
regulation of developmental processGO:00507932470.033
developmental growthGO:00485891660.033
transcription dna templatedGO:00063511810.033
Yeast
blood vessel developmentGO:00015682460.032
cellular carbohydrate metabolic processGO:004426240.032
negative regulation of cell communicationGO:0010648960.032
somitogenesisGO:0001756870.032
cellular protein metabolic processGO:00442671290.031
Yeast Fly
embryonic limb morphogenesisGO:003032620.031
neuron differentiationGO:00301823530.031
startle responseGO:000196440.031
small molecule metabolic processGO:0044281770.031
cell migrationGO:00164772370.030
negative regulation of cellular processGO:00485232830.030
Yeast
regulation of establishment or maintenance of cell polarityGO:003287820.030
histone modificationGO:0016570200.030
Yeast Fly
positive regulation of cell adhesionGO:004578510.030
extrinsic apoptotic signaling pathwayGO:009719130.030
regulation of protein catabolic processGO:004217610.030
regulation of stem cell proliferationGO:007209120.030
positive regulation of wound healingGO:009030310.030
axon developmentGO:00615641660.030
synaptic growth at neuromuscular junctionGO:005112420.030
negative regulation of autophagyGO:001050710.030
single organism nuclear importGO:190259330.029
neural crest formationGO:0014029140.029
regulation of cellular amino acid metabolic processGO:000652100.029
aromatic compound biosynthetic processGO:00194382170.029
Yeast
regulation of neural precursor cell proliferationGO:200017730.029
rna localizationGO:000640340.028
regulation of cellular biosynthetic processGO:00313262450.028
Yeast
neural crest cell differentiationGO:0014033720.028
establishment of protein localization to organelleGO:007259440.028
regulation of cell differentiationGO:00455951420.028
negative regulation of developmental processGO:0051093650.028
cellular response to external stimulusGO:007149620.027
cardiac cell fate commitmentGO:006091110.027
regulation of multicellular organism growthGO:004001440.027
regulation of cell communicationGO:00106462320.027
regulation of cellular ketone metabolic processGO:001056570.027
enzyme linked receptor protein signaling pathwayGO:00071671060.027
chromatin modificationGO:0016568210.027
Yeast Fly
nucleobase containing compound biosynthetic processGO:00346542050.026
Yeast
positive regulation of cellular catabolic processGO:003133130.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
Yeast
mesenchymal cell developmentGO:0014031780.026
negative regulation of cellular catabolic processGO:003133030.026
cell morphogenesis involved in neuron differentiationGO:00486671630.026
positive regulation of gliogenesisGO:001401520.026
cellular component movementGO:00069283350.026
somite developmentGO:0061053960.026
positive regulation of canonical wnt signaling pathwayGO:009026340.026
negative regulation of synapse assemblyGO:005196420.025
regulation of signal transductionGO:00099662250.025
lipid storageGO:001991510.025
protein modification processGO:00362111000.025
Yeast Fly
vasculature developmentGO:00019442780.025
regulation of cellular metabolic processGO:00313233200.025
Yeast
embryo development ending in birth or egg hatchingGO:00097922710.025
positive regulation of map kinase activityGO:004340630.025
positive regulation of secretion by cellGO:190353210.025
cellular amino acid metabolic processGO:000652070.024
spermatid developmentGO:000728620.024
cell surface receptor signaling pathwayGO:00071663250.024
cellular aromatic compound metabolic processGO:00067252950.024
Yeast
sleepGO:003043110.024
sialylationGO:009750340.024
lamellipodium assemblyGO:003003210.024
connective tissue developmentGO:0061448990.024
internal protein amino acid acetylationGO:000647520.024
nucleobase containing compound metabolic processGO:00061392740.024
Yeast
negative regulation of response to stimulusGO:00485851040.024
modification dependent protein catabolic processGO:001994130.023
lamellipodium organizationGO:009758110.023
positive regulation of secretionGO:005104710.023
cell projection organizationGO:00300302840.023
protein metabolic processGO:00195381830.023
Yeast Fly
cellular ketone metabolic processGO:0042180110.023
organonitrogen compound metabolic processGO:1901564740.023
positive regulation of cell proliferationGO:0008284150.023
negative regulation of gliogenesisGO:001401410.023
regulation of dendrite developmentGO:005077330.023
organic substance biosynthetic processGO:19015762890.023
Yeast
erk1 and erk2 cascadeGO:007037140.023
stem cell differentiationGO:00488631170.022
somatic stem cell maintenanceGO:003501910.022
regulation of skeletal muscle tissue developmentGO:004864140.022
locomotor rhythmGO:004547530.022
stem cell developmentGO:0048864820.021
negative regulation of cellular metabolic processGO:0031324770.021
Yeast
cell substrate adhesionGO:003158940.021
protein localization to nucleusGO:003450430.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
Yeast
cellular response to molecule of bacterial originGO:007121930.021
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.020
Yeast
regulation of autophagyGO:001050630.020
cellular component assembly involved in morphogenesisGO:00109271070.020
cellular response to growth factor stimulusGO:0071363390.020
regulation of dendrite morphogenesisGO:004881430.020
regulation of response to nutrient levelsGO:003210710.020
cellular amine metabolic processGO:004410620.020
positive regulation of catabolic processGO:000989640.020
chromosome organizationGO:0051276310.020
Yeast Fly
ear developmentGO:00435831270.020
positive regulation of biological processGO:00485182530.020
Yeast Fly
regulation of anatomical structure morphogenesisGO:00226031300.020
immune system processGO:00023762410.019
regulation of mitotic cell cycle embryonicGO:000979420.019
behaviorGO:0007610740.019
post golgi vesicle mediated transportGO:000689210.019
positive regulation of cell cycleGO:004578730.019
single organism organelle organizationGO:19025891990.019
Yeast Fly
regulation of cellular carbohydrate metabolic processGO:001067540.019
outflow tract morphogenesisGO:000315110.019
protein targeting to nucleusGO:004474430.019
regulation of protein bindingGO:004339330.019
response to organic substanceGO:00100331530.019
regulation of postsynaptic membrane potentialGO:006007810.018
ameboidal type cell migrationGO:00016671430.018
stem cell proliferationGO:007208940.018
negative regulation of signalingGO:0023057960.018
gastrulationGO:00073692080.018
cartilage developmentGO:0051216960.018
segmentationGO:0035282970.017
epidermis morphogenesisGO:004873040.017
protein complex disassemblyGO:004324110.017
mitotic cell cycle embryonicGO:004544820.017
macromolecular complex subunit organizationGO:0043933740.017
Yeast Fly
organelle organizationGO:00069962270.017
Yeast Fly
regulation of cellular protein catabolic processGO:190336210.017
transportGO:00068102200.017
negative regulation of protein phosphorylationGO:000193340.017
cellular response to nutrient levelsGO:003166920.017
cilium morphogenesisGO:0060271850.016
protein secretionGO:000930610.016
response to chemicalGO:00422213200.016
adherens junction organizationGO:003433240.016
regulation of biosynthetic processGO:00098892500.016
Yeast
regulation of primary metabolic processGO:00800903110.016
Yeast
negative regulation of nitrogen compound metabolic processGO:0051172590.016
Yeast
regulation of response to cytokine stimulusGO:006075930.016
cellular response to biotic stimulusGO:007121630.016
cellular response to extracellular stimulusGO:003166820.016
negative regulation of cytokine mediated signaling pathwayGO:000196020.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of rna metabolic processGO:00512522240.015
Yeast
cellular component assemblyGO:00226071700.015
negative regulation of kinase activityGO:003367340.015
dorsal ventral pattern formationGO:00099531250.015
macromolecular complex disassemblyGO:003298410.015
activation of jun kinase activityGO:000725720.015
regulation of production of molecular mediator of immune responseGO:000270010.015
response to external stimulusGO:00096052640.015
Yeast
regulation of cellular amine metabolic processGO:003323800.015
cellular macromolecule metabolic processGO:00442603910.015
Yeast Fly
internal peptidyl lysine acetylationGO:001839320.015
meiotic cell cycle processGO:190304630.015
transcription from rna polymerase ii promoterGO:0006366800.015
Yeast
negative regulation of muscle cell differentiationGO:005114810.015
positive regulation of transportGO:005105020.015
growthGO:00400071740.015
cellular component disassemblyGO:002241110.015
chemosensory behaviorGO:000763510.015
embryonic organ developmentGO:00485683810.015
regulation of cytoplasmic transportGO:190364940.015
negative regulation of cellular biosynthetic processGO:0031327550.015
Yeast
organic acid metabolic processGO:0006082310.015
heart contractionGO:0060047710.015
pigmentationGO:0043473850.015
anterior posterior pattern specificationGO:00099521520.015
heart developmentGO:00075073130.014
determination of heart left right asymmetryGO:00613711170.014
columnar cuboidal epithelial cell differentiationGO:0002065380.014
negative regulation of protein kinase activityGO:000646940.014
cellular protein modification processGO:00064641000.014
Yeast Fly
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
nitrogen compound metabolic processGO:00068073190.014
Yeast
negative regulation of catabolic processGO:000989530.014
meiotic nuclear divisionGO:000712640.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
ventricular cardiac muscle tissue developmentGO:000322930.014
amine metabolic processGO:000930820.014
organic cyclic compound biosynthetic processGO:19013622230.014
Yeast
nucleocytoplasmic transportGO:000691340.014
regulation of cell substrate adhesionGO:001081010.014
adult behaviorGO:003053420.014
autophagyGO:000691440.014
nuclear transportGO:005116940.014
oxoacid metabolic processGO:0043436310.014
tissue remodelingGO:004877140.014
specification of symmetryGO:00097992040.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
neuron projection guidanceGO:0097485860.014
glial cell proliferationGO:001400940.014
skin morphogenesisGO:004358970.013
commissural neuron axon guidanceGO:007167930.013
regulation of hormone secretionGO:004688320.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
positive regulation of response to stimulusGO:0048584800.013
sequestering of metal ionGO:005123830.013
osteoclast developmentGO:003603510.013
membrane invaginationGO:001032410.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
Yeast
hindbrain developmentGO:0030902910.013
macroautophagyGO:001623610.013
positive regulation of biosynthetic processGO:0009891680.013
Yeast
epithelial cell differentiationGO:00308551160.013
regulation of multicellular organismal processGO:00512392770.013
calcium ion transport into cytosolGO:006040230.013
cellular response to lipopolysaccharideGO:007122230.013
protein acetylationGO:000647320.013
neurological system processGO:0050877620.013
meiotic chromosome segregationGO:004513230.013
positive regulation of cell divisionGO:005178120.013
cell differentiation in spinal cordGO:0021515400.013
gtp catabolic processGO:000618420.013
negative regulation of translationGO:001714810.013
rna metabolic processGO:00160702190.013
Yeast
nuclear importGO:005117030.013
heart morphogenesisGO:00030071560.013
multicellular organism growthGO:003526440.013
sensory perception of painGO:001923310.013
response to vitaminGO:003327330.013
inner ear developmentGO:00488391260.012
golgi vesicle transportGO:004819330.012
muscle fiber developmentGO:0048747520.012
protein importGO:001703830.012
positive regulation of developmental processGO:0051094500.012
determination of bilateral symmetryGO:00098552040.012
positive regulation of multicellular organismal processGO:0051240520.012
respiratory electron transport chainGO:002290420.012
negative regulation of immune responseGO:005077720.012
multicellular organismal response to stressGO:003355520.012
neuron developmentGO:00486662620.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.012
cell migration involved in gastrulationGO:0042074790.012
pigment cell differentiationGO:0050931380.012
amide biosynthetic processGO:004360410.012
peptide transportGO:001583310.012
hormone secretionGO:004687920.012
regulation of receptor activityGO:001046920.012
regulation of organ morphogenesisGO:2000027350.012
negative regulation of cell differentiationGO:0045596460.012
regulation of cell morphogenesis involved in differentiationGO:0010769380.011
cellular component biogenesisGO:00440851780.011
antimicrobial humoral responseGO:001973020.011
regulation of meiotic cell cycleGO:005144510.011
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.011
regulation of neurological system processGO:003164420.011
taxisGO:00423301090.011
cytosolic calcium ion transportGO:006040130.011
alpha amino acid metabolic processGO:190160530.011
mesenchymal cell differentiationGO:0048762870.011
cell adhesion mediated by integrinGO:003362710.011
single organism localizationGO:19025782250.011
positive regulation of metabolic processGO:00098931080.011
Yeast Fly
convergent extension involved in axis elongationGO:0060028260.011
epithelial to mesenchymal transitionGO:0001837210.011
exocytosisGO:000688710.011
mesenchyme developmentGO:00604851270.011
regulation of calcium ion transportGO:005192420.011
negative regulation of stem cell differentiationGO:200073720.011
intracellular mrna localizationGO:000829810.011
cell matrix adhesionGO:000716040.011
cilium assemblyGO:0042384580.011
synaptic vesicle localizationGO:009747910.011
regulation of response to extracellular stimulusGO:003210410.011
proteasomal protein catabolic processGO:001049820.011
single organism carbohydrate metabolic processGO:0044723120.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
regulation of embryonic developmentGO:0045995470.011
response to mechanical stimulusGO:0009612240.011
spermatid differentiationGO:004851520.011
modification dependent macromolecule catabolic processGO:004363230.011
neuron migrationGO:0001764220.011
somatic muscle developmentGO:000752540.011
nuclear exportGO:005116810.011
organelle localizationGO:0051640490.011
regulation of protein transportGO:005122330.010
macromolecule deacylationGO:009873230.010
axon guidanceGO:0007411860.010
positive regulation of cellular amine metabolic processGO:003324000.010
positive regulation of chromosome organizationGO:200125210.010
regulation of establishment of planar polarityGO:009017540.010
regulation of nervous system developmentGO:0051960900.010
post anal tail morphogenesisGO:0036342190.010
cell substrate adherens junction assemblyGO:000704510.010
regulation of response to oxidative stressGO:190288220.010
regulation of nucleocytoplasmic transportGO:004682220.010
actin polymerization or depolymerizationGO:000815420.010
neuroblast proliferationGO:000740520.010
negative regulation of neurogenesisGO:0050768200.010
spindle assemblyGO:005122520.010

kdm4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
organ system cancerDOID:005068600.013