Danio rerio

87 known processes

pitx2

paired-like homeodomain transcription factor 2

(Aliases: pitx2a,pitx2c,zgc:110508,MGC110508)

pitx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heterocycle metabolic processGO:00464832900.994
Human Zebrafish Mouse Rat Worm
regionalizationGO:00030022740.987
erythrocyte differentiationGO:0030218540.984
central nervous system developmentGO:00074173870.982
Zebrafish Mouse Rat
myeloid cell homeostasisGO:0002262560.978
digestive system developmentGO:00551232890.975
erythrocyte homeostasisGO:0034101550.965
nucleobase containing compound metabolic processGO:00061392740.965
Human Zebrafish Mouse Rat Worm
generation of neuronsGO:00486993850.964
Mouse Rat Worm Fly
embryonic organ developmentGO:00485683810.959
transcription dna templatedGO:00063511810.955
Human Zebrafish Mouse Rat Worm
cellular aromatic compound metabolic processGO:00067252950.954
Human Zebrafish Mouse Rat Worm
specification of symmetryGO:00097992040.948
nucleic acid metabolic processGO:00903042440.942
Human Zebrafish Mouse Rat Worm
regulation of biological qualityGO:00650082630.941
morphogenesis of an epithelial sheetGO:0002011490.937
regulation of cellular metabolic processGO:00313233200.932
Human Zebrafish Mouse Rat Worm
aromatic compound biosynthetic processGO:00194382170.928
Human Zebrafish Mouse Rat Worm
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.927
Human Mouse Rat Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.916
Human Zebrafish Mouse Rat Worm
regulation of nucleic acid templated transcriptionGO:19035062130.916
Human Zebrafish Mouse Rat Worm
skeletal system developmentGO:00015011810.909
organic cyclic compound metabolic processGO:19013603010.907
Human Zebrafish Mouse Rat Worm
embryonic skeletal system morphogenesisGO:0048704930.899
cellular macromolecule biosynthetic processGO:00346452240.884
Human Zebrafish Mouse Rat Worm
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.880
Human
positive regulation of metabolic processGO:00098931080.878
Human Zebrafish Mouse Rat Worm
regulation of gene expressionGO:00104682650.875
Human Zebrafish Mouse Rat Worm
organic cyclic compound biosynthetic processGO:19013622230.841
Human Zebrafish Mouse Rat Worm
chordate embryonic developmentGO:00430092710.840
positive regulation of macromolecule metabolic processGO:0010604930.832
Human Zebrafish Mouse Rat Worm
negative regulation of cellular processGO:00485232830.832
Human
embryonic skeletal system developmentGO:0048706970.829
positive regulation of rna metabolic processGO:0051254590.826
Human Zebrafish Mouse Rat Worm
positive regulation of nitrogen compound metabolic processGO:0051173690.823
Human Zebrafish Mouse Rat Worm
regulation of biosynthetic processGO:00098892500.822
Human Zebrafish Mouse Rat Worm
cell differentiation in spinal cordGO:0021515400.811
regulation of multicellular organismal processGO:00512392770.797
hemopoiesisGO:00300971830.795
regulation of cellular biosynthetic processGO:00313262450.786
Human Zebrafish Mouse Rat Worm
regulation of rna biosynthetic processGO:20011412130.786
Human Zebrafish Mouse Rat Worm
heterocycle biosynthetic processGO:00181302150.785
Human Zebrafish Mouse Rat Worm
regulation of nitrogen compound metabolic processGO:00511712510.780
Human Zebrafish Mouse Rat Worm
regulation of transcription dna templatedGO:00063552130.777
Human Zebrafish Mouse Rat Worm
homeostasis of number of cellsGO:0048872620.775
positive regulation of cellular metabolic processGO:0031325940.769
Human Zebrafish Mouse Rat Worm
muscle structure developmentGO:00610611960.751
Mouse
pituitary gland developmentGO:0021983160.747
Zebrafish Mouse
otic placode formationGO:0043049230.746
determination of heart left right asymmetryGO:00613711170.745
positive regulation of nucleic acid templated transcriptionGO:1903508570.738
Human Zebrafish Mouse Rat Worm
diencephalon developmentGO:0021536580.734
Zebrafish Mouse
gland developmentGO:00487321430.733
Zebrafish Mouse
digestive tract morphogenesisGO:00485462310.730
Mouse
rna metabolic processGO:00160702190.727
Human Zebrafish Mouse Rat Worm
regulation of cellular macromolecule biosynthetic processGO:20001122220.724
Human Zebrafish Mouse Rat Worm
neuron projection guidanceGO:0097485860.709
Worm
immune system processGO:00023762410.705
Mouse
positive regulation of neuron migrationGO:200122420.704
cell proliferationGO:0008283800.700
Mouse
ectodermal placode developmentGO:0071696370.698
positive regulation of gene expressionGO:0010628710.694
Human Zebrafish Mouse Rat Worm
embryonic viscerocranium morphogenesisGO:0048703520.683
digestive tract developmentGO:00485652650.678
transcription from rna polymerase ii promoterGO:0006366800.673
Human Mouse Rat Worm
regulation of metabolic processGO:00192223590.673
Human Zebrafish Mouse Rat Worm
regulation of rna metabolic processGO:00512522240.667
Human Zebrafish Mouse Rat Worm
eye morphogenesisGO:00485921440.665
regulation of macromolecule biosynthetic processGO:00105562250.658
Human Zebrafish Mouse Rat Worm
nitrogen compound metabolic processGO:00068073190.658
Human Zebrafish Mouse Rat Worm
neuron fate commitmentGO:0048663260.654
behaviorGO:0007610740.648
regulation of primary metabolic processGO:00800903110.647
Human Zebrafish Mouse Rat Worm
spinal cord developmentGO:0021510460.626
positive regulation of macromolecule biosynthetic processGO:0010557590.621
Human Zebrafish Mouse Rat Worm
sensory organ morphogenesisGO:00905962000.620
gene expressionGO:00104672520.616
Human Zebrafish Mouse Rat Worm
cell fate specificationGO:0001708680.599
cellular component movementGO:00069283350.597
Mouse Worm
head developmentGO:00603223030.597
nucleic acid templated transcriptionGO:00976591810.596
Human Zebrafish Mouse Rat Worm
cell projection morphogenesisGO:00488582440.592
Worm Fly
cell fate commitmentGO:0045165990.590
regulation of vascular permeabilityGO:004311450.580
muscle cell differentiationGO:00426921390.573
Mouse
inner ear morphogenesisGO:0042472630.572
brain developmentGO:00074202930.561
Zebrafish Mouse Rat
cellular nitrogen compound biosynthetic processGO:00442712180.557
Human Zebrafish Mouse Rat Worm
cell migrationGO:00164772370.553
Mouse
organic substance biosynthetic processGO:19015762890.549
Human Zebrafish Mouse Rat Worm
mesenchyme developmentGO:00604851270.540
Mouse
stem cell proliferationGO:007208940.522
otic vesicle morphogenesisGO:0071600340.510
positive regulation of cellular biosynthetic processGO:0031328680.503
Human Zebrafish Mouse Rat Worm
negative regulation of transcription dna templatedGO:0045892450.499
Human
determination of bilateral symmetryGO:00098552040.489
otic vesicle formationGO:0030916270.478
negative regulation of nucleic acid templated transcriptionGO:1903507450.477
Human
cell migration to the midline involved in heart developmentGO:0003318120.475
cardioblast migration to the midline involved in heart field formationGO:006097570.473
circulatory system processGO:0003013870.469
heart processGO:0003015710.468
neural crest cell differentiationGO:0014033720.464
Mouse
embryonic organ morphogenesisGO:00485622740.462
epidermal cell differentiationGO:0009913360.457
nucleobase containing compound biosynthetic processGO:00346542050.456
Human Zebrafish Mouse Rat Worm
striated muscle tissue developmentGO:00147061100.444
Mouse
central nervous system myelin formationGO:003228910.437
embryonic cranial skeleton morphogenesisGO:0048701900.435
anterior posterior pattern specificationGO:00099521520.432
ectodermal placode morphogenesisGO:0071697320.430
sensory organ developmentGO:00074233930.430
gastrulation with mouth forming secondGO:0001702440.427
positive regulation of biosynthetic processGO:0009891680.426
Human Zebrafish Mouse Rat Worm
mesoderm developmentGO:0007498880.420
gastrulationGO:00073692080.419
left right pattern formationGO:0060972190.416
primitive hemopoiesisGO:0060215270.414
tube morphogenesisGO:00352393490.409
Mouse
mesoderm morphogenesisGO:0048332510.405
agingGO:000756820.399
oligodendrocyte differentiationGO:0048709230.398
embryonic camera type eye formationGO:0060900100.396
macromolecule biosynthetic processGO:00090592270.393
Human Zebrafish Mouse Rat Worm
heart field specificationGO:000312810.391
negative regulation of nucleobase containing compound metabolic processGO:0045934590.390
Human
appendage developmentGO:0048736800.389
Human Mouse
thyroid gland developmentGO:0030878120.380
positive regulation of cellular processGO:00485222010.378
Human Zebrafish Mouse Rat Worm
cell motilityGO:00488702440.377
Mouse
cellular macromolecule metabolic processGO:00442603910.376
Human Zebrafish Mouse Rat Worm
negative regulation of muscle tissue developmentGO:190186220.376
foregut morphogenesisGO:000744040.375
wnt signaling pathwayGO:0016055800.375
Mouse
cranial nerve developmentGO:0021545420.374
heart developmentGO:00075073130.373
regulation of developmental processGO:00507932470.373
negative regulation of biological processGO:00485193040.371
Human
positive regulation of biological processGO:00485182530.368
Human Zebrafish Mouse Rat Worm
cardioblast migrationGO:000326070.366
endoderm developmentGO:0007492490.366
cell morphogenesisGO:00009022890.364
Worm Fly
embryonic hemopoiesisGO:0035162530.361
negative regulation of gene expressionGO:0010629650.352
Human
regulation of cell differentiationGO:00455951420.350
positive regulation of transcription dna templatedGO:0045893570.348
Human Zebrafish Mouse Rat Worm
endocrine system developmentGO:0035270650.343
Zebrafish Mouse
homeostatic processGO:00425921420.338
taxisGO:00423301090.336
Worm
blood circulationGO:0008015870.327
optic cup morphogenesis involved in camera type eye developmentGO:000207270.326
heart formationGO:0060914130.325
striated muscle cell differentiationGO:00511461290.324
Mouse
mesenchymal cell developmentGO:0014031780.312
Mouse
localization of cellGO:00516742440.311
Mouse
camera type eye developmentGO:00430102220.310
axon guidanceGO:0007411860.308
Worm
ectodermal placode formationGO:0060788260.303
rna biosynthetic processGO:00327741810.300
Human Zebrafish Mouse Rat Worm
cellular biosynthetic processGO:00442492860.296
Human Zebrafish Mouse Rat Worm
regulation of erythrocyte differentiationGO:004564620.289
negative regulation of cellular metabolic processGO:0031324770.285
Human
atrioventricular valve formationGO:000319030.284
connective tissue developmentGO:0061448990.280
neuroepithelial cell differentiationGO:0060563260.277
ear morphogenesisGO:0042471640.275
regulation of neuron migrationGO:200122220.274
oligodendrocyte cell fate specificationGO:002177840.273
regulation of transcription from rna polymerase ii promoterGO:00063571140.273
Human Mouse Rat Worm
cardiac muscle cell differentiationGO:0055007300.272
Mouse
axonogenesisGO:00074091520.270
Worm
embryonic heart tube developmentGO:00350501330.269
positive regulation of nervous system developmentGO:0051962250.252
heart valve formationGO:000318840.248
positive regulation of nucleobase containing compound metabolic processGO:0045935690.239
Human Zebrafish Mouse Rat Worm
larval developmentGO:000216420.235
forebrain neuron fate commitmentGO:002187710.234
system processGO:00030081850.233
regulation of macromolecule metabolic processGO:00602553170.232
Human Zebrafish Mouse Rat Worm
ventral spinal cord developmentGO:0021517350.226
ear developmentGO:00435831270.226
semicircular canal developmentGO:0060872240.225
tissue regenerationGO:0042246740.223
cardiac muscle tissue developmentGO:0048738480.223
Mouse
regulation of heart morphogenesisGO:2000826170.221
female sex differentiationGO:004666040.221
Rat
regulation of heart contractionGO:0008016320.220
hematopoietic or lymphoid organ developmentGO:00485341910.219
Mouse
negative regulation of cellular biosynthetic processGO:0031327550.219
Human
negative regulation of biosynthetic processGO:0009890550.218
Human
nerve developmentGO:0021675450.218
cell migration involved in gastrulationGO:0042074790.216
cartilage developmentGO:0051216960.215
heart joggingGO:0003146400.211
epidermal cell fate specificationGO:000995740.210
positive regulation of rna biosynthetic processGO:1902680570.210
Human Zebrafish Mouse Rat Worm
embryo development ending in birth or egg hatchingGO:00097922710.206
cell growthGO:0016049570.201
heart contractionGO:0060047710.201
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.200
columnar cuboidal epithelial cell differentiationGO:0002065380.199
otic vesicle developmentGO:0071599420.197
formation of primary germ layerGO:0001704620.195
locomotionGO:00400113130.194
Mouse Worm
neural plate pattern specificationGO:0060896120.192
muscle tissue developmentGO:00605371100.191
Mouse
endodermal cell fate determinationGO:000749320.189
regulation of multicellular organismal developmentGO:20000262230.184
adenohypophysis developmentGO:0021984150.183
Zebrafish
epithelial cell differentiationGO:00308551160.182
endodermal cell differentiationGO:0035987190.181
cardiac chamber formationGO:000320740.177
negative regulation of macromolecule metabolic processGO:0010605760.169
Human
mechanoreceptor differentiationGO:0042490370.168
protein targeting to nucleusGO:004474430.168
axon developmentGO:00615641660.168
Worm
central nervous system myelinationGO:002201020.165
cell surface receptor signaling pathwayGO:00071663250.165
Mouse
forebrain developmentGO:0030900960.164
Zebrafish Mouse
auditory receptor cell fate commitmentGO:000991240.164
enteric nervous system developmentGO:0048484120.162
regulation of epithelial cell proliferationGO:005067830.161
epidermis developmentGO:0008544480.159
cellular component morphogenesisGO:00329893360.159
Worm Fly
response to external stimulusGO:00096052640.158
Rat Worm
lens development in camera type eyeGO:0002088220.158
Zebrafish
apoptotic processGO:00069151160.158
negative regulation of rna biosynthetic processGO:1902679450.152
Human
skeletal system morphogenesisGO:00487051020.148
neural tube developmentGO:0021915620.147
cellular nitrogen compound metabolic processGO:00346412900.146
Human Zebrafish Mouse Rat Worm
neuron differentiationGO:00301823530.145
Rat Worm Fly
determination of left right symmetryGO:00073681790.145
response to chemicalGO:00422213200.144
Rat Worm
hindbrain developmentGO:0030902910.143
cell deathGO:00082191210.138
ventricular cardiac muscle tissue morphogenesisGO:005501020.137
wound healingGO:0042060900.137
retina development in camera type eyeGO:00600411460.137
floor plate developmentGO:0033504150.136
positive regulation of axon guidanceGO:190266910.134
hair cell differentiationGO:0035315320.134
response to organic substanceGO:00100331530.132
Rat
glial cell migrationGO:000834730.132
positive regulation of muscle cell differentiationGO:005114910.130
pancreatic a cell developmentGO:000332220.128
nucleocytoplasmic transportGO:000691340.127
nuclear transportGO:005116940.127
pectoral fin developmentGO:0033339500.126
gamete generationGO:0007276330.125
ventral spinal cord interneuron differentiationGO:0021514120.124
embryonic retina morphogenesis in camera type eyeGO:0060059220.124
regulation of apoptotic processGO:0042981980.124
myotube differentiationGO:0014902450.123
Mouse
cranial ganglion developmentGO:006155030.122
regulation of endodermal cell fate specificationGO:0042663150.121
regulation of programmed cell deathGO:00430671010.118
neuroblast proliferationGO:000740520.118
astrocyte differentiationGO:004870810.118
endodermal cell fate specificationGO:0001714170.117
pancreas developmentGO:0031016840.116
dorsal ventral pattern formationGO:00099531250.116
signal transductionGO:00071654550.116
cellular component assemblyGO:00226071700.116
sympathetic nervous system developmentGO:004848530.115
cellular component assembly involved in morphogenesisGO:00109271070.114
camera type eye morphogenesisGO:00485931080.113
post embryonic morphogenesisGO:000988640.112
cell morphogenesis involved in differentiationGO:00009041950.108
Worm Fly
regulation of dna metabolic processGO:0051052110.104
epibolyGO:0090504410.104
lymphocyte proliferationGO:004665110.104
cellular response to chemical stimulusGO:00708871570.103
regulation of cellular component organizationGO:0051128860.103
morphogenesis of an epitheliumGO:00020093330.102
bmp signaling pathwayGO:0030509520.102
negative regulation of nitrogen compound metabolic processGO:0051172590.101
Human
ossificationGO:0001503230.101
mesenchymal cell differentiationGO:0048762870.100
Mouse
regulation of gastrulationGO:0010470240.098
retina morphogenesis in camera type eyeGO:0060042790.097
spinal cord oligodendrocyte cell fate specificationGO:002153020.097
central nervous system neuron differentiationGO:0021953740.095
regulation of cell proliferationGO:0042127370.095
Mouse
exocrine pancreas developmentGO:0031017280.094
inner ear receptor cell fate commitmentGO:006012040.094
embryonic neurocranium morphogenesisGO:0048702150.094
embryonic heart tube morphogenesisGO:00031431080.093
negative regulation of metabolic processGO:0009892860.093
Human
hatching gland developmentGO:004878530.092
myeloid cell differentiationGO:0030099860.091
type b pancreatic cell developmentGO:000332340.091
mesoderm formationGO:0001707430.091
pigmentationGO:0043473850.089
development of primary female sexual characteristicsGO:004654540.089
Rat
aorta developmentGO:003590440.089
cell fate commitment involved in formation of primary germ layerGO:0060795260.088
neural crest cell migrationGO:0001755420.086
Mouse
negative regulation of response to stimulusGO:00485851040.085
closure of optic fissureGO:006138660.084
head morphogenesisGO:006032380.084
germ line stem cell maintenanceGO:003071820.082
response to growth factorGO:0070848390.082
endodermal cell fate commitmentGO:0001711180.082
mononuclear cell proliferationGO:003294310.080
embryonic digestive tract morphogenesisGO:004855730.079
Mouse
glial cell fate commitmentGO:002178160.079
glial cell fate specificationGO:002178040.079
inner ear developmentGO:00488391260.078
cell projection organizationGO:00300302840.077
Worm Fly
biosynthetic processGO:00090582940.076
Human Zebrafish Mouse Rat Worm
eye developmentGO:00016542770.076
convergent extension involved in organogenesisGO:0060029100.076
regulation of molecular functionGO:0065009700.076
Mouse
pectoral fin morphogenesisGO:0035138290.076
positive regulation of epithelial cell differentiationGO:003085820.075
axon ensheathment in central nervous systemGO:003229120.075
regulation of bindingGO:005109830.074
Mouse
stem cell divisionGO:001714510.074
positive regulation of striated muscle cell differentiationGO:005115510.073
heart loopingGO:0001947940.073
sprouting angiogenesisGO:0002040530.073
positive regulation of cellular component movementGO:0051272110.072
ovarian follicle developmentGO:000154120.070
neural plate regionalizationGO:0060897100.069
regulation of organ growthGO:004662030.068
regulation of mesenchymal cell proliferationGO:001046410.067
response to lipidGO:0033993600.067
Rat
liver developmentGO:0001889960.066
glial cell differentiationGO:0010001420.066
positive regulation of epithelial cell proliferationGO:005067910.065
dorsal aorta morphogenesisGO:003591230.065
water homeostasisGO:003010440.064
male gamete generationGO:004823270.063
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.062
regulation of neurogenesisGO:0050767870.062
pharyngeal muscle developmentGO:004328240.061
photoreceptor cell differentiationGO:0046530550.061
atrial cardiac muscle cell differentiationGO:005501150.060
developmental pigmentationGO:0048066480.060
lens morphogenesis in camera type eyeGO:000208970.059
positive regulation of mesenchymal cell proliferationGO:000205310.058
positive regulation of cell migrationGO:0030335110.058
neuron fate specificationGO:0048665200.057
positive regulation of stem cell proliferationGO:200064810.057
hepaticobiliary system developmentGO:0061008980.056
myeloid cell developmentGO:0061515320.056
ovulation cycleGO:004269820.055
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.054
mesenchymal cell proliferationGO:001046310.053
leukocyte proliferationGO:007066110.053
spinal cord motor neuron differentiationGO:0021522260.053
skin developmentGO:0043588540.052
axon extensionGO:0048675450.052
regulation of cell communicationGO:00106462320.052
regulation of cell deathGO:00109411030.052
negative regulation of mesodermal cell fate specificationGO:004266230.052
neuronal action potentialGO:0019228180.052
enzyme linked receptor protein signaling pathwayGO:00071671060.051
endocrine pancreas developmentGO:0031018270.051
positive regulation of cell motilityGO:2000147110.051
ventral midline developmentGO:0007418130.050
artery developmentGO:0060840220.050
telencephalon developmentGO:0021537140.049
negative regulation of leukocyte differentiationGO:190210610.049
bmp signaling pathway involved in heart joggingGO:0003303140.049
stem cell maintenanceGO:001982740.049
regulation of locomotionGO:0040012550.049
Mouse Worm
positive regulation of oligodendrocyte differentiationGO:004871410.048
motor neuron axon guidanceGO:0008045230.048
dorsal ventral neural tube patterningGO:002190410.048
cardiac muscle tissue regenerationGO:006102630.048
macrophage differentiationGO:003022570.047
inner ear receptor cell differentiationGO:0060113290.047
female gonad developmentGO:000858540.046
Rat
determination of left right asymmetry in nervous systemGO:003554540.046
anterior posterior axis specificationGO:0009948200.046
endocardium formationGO:006021410.046
pigment cell differentiationGO:0050931380.045
muscle cell developmentGO:00550011150.044
Mouse
polarized epithelial cell differentiationGO:003085940.044
fin developmentGO:0033333770.044
programmed cell deathGO:00125011190.043
positive regulation of cell differentiationGO:0045597300.043
negative regulation of cell differentiationGO:0045596460.043
positive regulation of gastrulationGO:200054320.043
negative regulation of myeloid cell differentiationGO:004563810.042
fin morphogenesisGO:0033334530.042
regenerationGO:0031099910.042
mesodermal cell fate specificationGO:0007501120.042
regulation of cardiac muscle tissue developmentGO:005502410.042
positive regulation of neurogenesisGO:0050769240.041
pancreatic d cell differentiationGO:000331120.041
regulation of signalingGO:00230512350.041
oligodendrocyte developmentGO:001400370.041
activin receptor signaling pathwayGO:003292480.040
stem cell developmentGO:0048864820.040
Mouse
epiboly involved in gastrulation with mouth forming secondGO:0055113350.040
regulation of organ morphogenesisGO:2000027350.040
monocyte differentiationGO:003022420.040
lateral line ganglion developmentGO:004889020.040
midbrain hindbrain boundary developmentGO:0030917230.040
intestinal epithelial cell differentiationGO:006057530.039
erythrocyte developmentGO:0048821240.039
muscle organ morphogenesisGO:004864480.038
Mouse
hepatocyte differentiationGO:007036510.038
negative regulation of muscle organ developmentGO:004863550.038
multi organism processGO:00517041340.037
forebrain regionalizationGO:002187140.037
odontogenesis of dentin containing toothGO:004247510.037
Rat
neuron fate determinationGO:004866420.037
anterior commissure morphogenesisGO:002196030.036
adult behaviorGO:003053420.036
ventricular cardiac muscle tissue developmentGO:000322930.036
canonical wnt signaling pathwayGO:0060070480.036
definitive hemopoiesisGO:0060216180.036
cell migration involved in heart formationGO:0060974100.035
medial fin morphogenesisGO:0035141140.034
regulation of epidermis developmentGO:004568220.034
trigeminal nerve developmentGO:002155930.034
negative regulation of cell proliferationGO:000828580.034
striated muscle cell developmentGO:00550021080.034
Mouse
stem cell differentiationGO:00488631170.034
Mouse
ectoderm formationGO:000170520.034
fin regenerationGO:0031101510.034
regulation of transcription involved in cell fate commitmentGO:006085010.033
midbrain developmentGO:0030901280.033
atrioventricular valve morphogenesisGO:000318160.033
endoderm formationGO:0001706290.033
neural plate anterior posterior regionalizationGO:002199980.033
forebrain generation of neuronsGO:0021872140.032
heart morphogenesisGO:00030071560.032
Mouse
neural nucleus developmentGO:0048857150.032
Mouse
organonitrogen compound metabolic processGO:1901564740.032
response to glucocorticoidGO:005138410.032
immune system developmentGO:00025201910.032
Mouse
nuclear importGO:005117030.031
post embryonic foregut morphogenesisGO:004861830.031
artery morphogenesisGO:0048844140.030
multi organism reproductive processGO:0044703360.030
striated muscle cell proliferationGO:001485570.030
stem cell fate determinationGO:004886710.030
lateral line nerve glial cell differentiationGO:004889560.030
neuroblast differentiationGO:001401610.029
response to abiotic stimulusGO:00096281220.029
cellular response to growth factor stimulusGO:0071363390.029
optomotor responseGO:007163210.029
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.029
Human
embryonic pectoral fin morphogenesisGO:0035118240.029
endocardial cushion morphogenesisGO:000320330.029
somatic muscle developmentGO:000752540.028
epithelial tube morphogenesisGO:00605621480.028
Mouse
myelin assemblyGO:003228810.028
positive regulation of muscle tissue developmentGO:190186310.028
embryonic appendage morphogenesisGO:0035113300.028
Mouse
pronephric glomerulus developmentGO:0039021130.027
exocrine system developmentGO:0035272280.027
protein localization to nucleusGO:003450430.027
ameboidal type cell migrationGO:00016671430.027
Mouse
nephron tubule epithelial cell differentiationGO:007216010.027
determination of digestive tract left right asymmetryGO:0071907100.027
muscle cell fate commitmentGO:004269390.027
apoptotic process involved in developmentGO:190274220.027
oligodendrocyte cell fate commitmentGO:002177950.027
ganglion developmentGO:006154850.026
sex determinationGO:000753010.026
regulation of glial cell differentiationGO:004568540.026
cell cycle g1 s phase transitionGO:004484310.026
positive regulation of endothelial cell differentiationGO:004560320.026
mesendoderm developmentGO:0048382100.026
response to woundingGO:00096111160.026
deathGO:00162651210.026
appendage morphogenesisGO:0035107560.026
Mouse
gabaergic neuron differentiationGO:009715420.026
Worm
primitive erythrocyte differentiationGO:006031950.026
cell proliferation in forebrainGO:002184630.026
cell differentiation in hindbrainGO:002153350.025
nephron epithelium morphogenesisGO:007208810.025
determination of pancreatic left right asymmetryGO:0035469110.025
negative regulation of macromolecule biosynthetic processGO:0010558480.025
Human
regulation of sequence specific dna binding transcription factor activityGO:005109090.025
negative regulation of programmed cell deathGO:0043069580.024
positive regulation of programmed cell deathGO:0043068290.024
positive regulation of leukocyte differentiationGO:190210710.024
positive regulation of cellular catabolic processGO:003133130.024
glomerulus morphogenesisGO:007210270.024
semicircular canal morphogenesisGO:0048752180.024
organic hydroxy compound biosynthetic processGO:190161760.024
negative regulation of apoptotic processGO:0043066550.024
monocarboxylic acid biosynthetic processGO:0072330120.024

pitx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:008000600.050
disease of anatomical entityDOID:700.050
bone diseaseDOID:008000100.050
musculoskeletal system diseaseDOID:1700.050
connective tissue diseaseDOID:6500.050