Danio rerio

0 known processes

pitx1

paired-like homeodomain transcription factor 1

(Aliases: zgc:136976,MGC136976)

pitx1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.270
Zebrafish
cellular biosynthetic processGO:00442492860.250
Zebrafish Mouse Rat Worm
regulation of cellular macromolecule biosynthetic processGO:20001122220.234
Zebrafish Mouse Rat Worm
organic cyclic compound biosynthetic processGO:19013622230.223
Zebrafish Mouse Rat Worm
cellular nitrogen compound biosynthetic processGO:00442712180.183
Zebrafish Mouse Rat Worm
aromatic compound biosynthetic processGO:00194382170.182
Zebrafish Mouse Rat Worm
regulation of cellular metabolic processGO:00313233200.180
Zebrafish Mouse Rat Worm
macromolecule biosynthetic processGO:00090592270.158
Zebrafish Mouse Rat Worm
gene expressionGO:00104672520.154
Zebrafish Mouse Rat Worm
embryonic organ morphogenesisGO:00485622740.147
Zebrafish
rna biosynthetic processGO:00327741810.145
Zebrafish Mouse Rat Worm
cellular macromolecule biosynthetic processGO:00346452240.128
Zebrafish Mouse Rat Worm
nucleic acid metabolic processGO:00903042440.126
Zebrafish Mouse Rat Worm
cellular nitrogen compound metabolic processGO:00346412900.122
Zebrafish Mouse Rat Worm
nitrogen compound metabolic processGO:00068073190.117
Zebrafish Mouse Rat Worm
embryonic skeletal system developmentGO:0048706970.117
Zebrafish
embryo development ending in birth or egg hatchingGO:00097922710.116
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.108
Zebrafish Mouse Rat Worm
regulation of biosynthetic processGO:00098892500.106
Zebrafish Mouse Rat Worm
rna metabolic processGO:00160702190.103
Zebrafish Mouse Rat Worm
water homeostasisGO:003010440.102
blood vessel morphogenesisGO:00485142160.101
oxoacid metabolic processGO:0043436310.100
cellular aromatic compound metabolic processGO:00067252950.096
Zebrafish Mouse Rat Worm
regulation of gene expressionGO:00104682650.094
Zebrafish Mouse Rat Worm
protein import into nucleusGO:000660630.094
regionalizationGO:00030022740.093
Zebrafish
regulation of rna biosynthetic processGO:20011412130.090
Zebrafish Mouse Rat Worm
embryonic organ developmentGO:00485683810.088
Zebrafish
compound eye developmentGO:004874920.087
vasculature developmentGO:00019442780.086
regulation of transcription dna templatedGO:00063552130.084
Zebrafish Mouse Rat Worm
heterocycle biosynthetic processGO:00181302150.079
Zebrafish Mouse Rat Worm
positive regulation of nucleic acid templated transcriptionGO:1903508570.078
Zebrafish Mouse Worm
germ line stem cell maintenanceGO:003071820.078
nuclear transportGO:005116940.076
blood vessel developmentGO:00015682460.076
positive regulation of macromolecule biosynthetic processGO:0010557590.076
Zebrafish Mouse Worm
biosynthetic processGO:00090582940.075
Zebrafish Mouse Rat Worm
regulation of multicellular organism growthGO:004001440.071
floor plate developmentGO:0033504150.071
embryonic skeletal system morphogenesisGO:0048704930.069
Zebrafish
regulation of protein transportGO:005122330.068
transcription from rna polymerase ii promoterGO:0006366800.066
Mouse Worm
multicellular organism growthGO:003526440.064
positive regulation of biological processGO:00485182530.064
Zebrafish Mouse Worm
nucleic acid templated transcriptionGO:00976591810.062
Zebrafish Mouse Rat Worm
homeostatic processGO:00425921420.061
regulation of nitrogen compound metabolic processGO:00511712510.061
Zebrafish Mouse Rat Worm
phagocytosisGO:000690930.060
protein importGO:001703830.060
regulation of epithelial cell proliferationGO:005067830.057
agingGO:000756820.057
protein targeting to nucleusGO:004474430.055
cellular macromolecule metabolic processGO:00442603910.055
Zebrafish Mouse Rat Worm
endoderm developmentGO:0007492490.055
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.054
Zebrafish Mouse Rat Worm
dorsal ventral pattern formationGO:00099531250.054
cellular component movementGO:00069283350.053
Worm
positive regulation of cellular biosynthetic processGO:0031328680.052
Zebrafish Mouse Worm
meiotic nuclear divisionGO:000712640.052
regulation of macromolecule biosynthetic processGO:00105562250.052
Zebrafish Mouse Rat Worm
stem cell maintenanceGO:001982740.051
regulation of rna metabolic processGO:00512522240.051
Zebrafish Mouse Rat Worm
heterocycle metabolic processGO:00464832900.051
Zebrafish Mouse Rat Worm
embryonic cranial skeleton morphogenesisGO:0048701900.050
Zebrafish
establishment of protein localization to organelleGO:007259440.050
larval developmentGO:000216420.050
positive regulation of nucleobase containing compound metabolic processGO:0045935690.050
Zebrafish Mouse Worm
nucleobase containing compound biosynthetic processGO:00346542050.049
Zebrafish Mouse Rat Worm
positive regulation of rna metabolic processGO:0051254590.049
Zebrafish Mouse Worm
regulation of cellular biosynthetic processGO:00313262450.047
Zebrafish Mouse Rat Worm
determination of bilateral symmetryGO:00098552040.047
Zebrafish
immune system developmentGO:00025201910.046
organic cyclic compound metabolic processGO:19013603010.046
Zebrafish Mouse Rat Worm
stem cell proliferationGO:007208940.044
regulation of metabolic processGO:00192223590.043
Zebrafish Mouse Rat Worm
regulation of multicellular organismal processGO:00512392770.043
energy reserve metabolic processGO:000611220.043
positive regulation of cellular processGO:00485222010.043
Zebrafish Mouse Worm
positive regulation of metabolic processGO:00098931080.043
Zebrafish Mouse Worm
regulation of biological qualityGO:00650082630.043
Zebrafish
single organism metabolic processGO:00447102170.042
organic substance biosynthetic processGO:19015762890.042
Zebrafish Mouse Rat Worm
regulation of stem cell differentiationGO:200073640.042
localization of cellGO:00516742440.042
regulation of macromolecule metabolic processGO:00602553170.041
Zebrafish Mouse Rat Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.040
Mouse Worm
inner ear developmentGO:00488391260.040
positive regulation of cell cycleGO:004578730.039
eye morphogenesisGO:00485921440.039
Zebrafish
cartilage developmentGO:0051216960.038
Mouse
stem cell developmentGO:0048864820.037
regulation of primary metabolic processGO:00800903110.037
Zebrafish Mouse Rat Worm
organic acid metabolic processGO:0006082310.037
carboxylic acid metabolic processGO:0019752220.036
digestive system developmentGO:00551232890.036
Zebrafish
somatic stem cell maintenanceGO:003501910.036
regulation of developmental processGO:00507932470.035
lateral inhibitionGO:004633110.035
nucleocytoplasmic transportGO:000691340.035
muscle tissue developmentGO:00605371100.035
Mouse
regulation of meiotic cell cycleGO:005144510.035
response to woundingGO:00096111160.035
digestive tract developmentGO:00485652650.034
Zebrafish
regulation of cytoplasmic transportGO:190364940.034
negative regulation of biological processGO:00485193040.034
negative regulation of cellular processGO:00485232830.033
response to stressGO:00069502630.033
establishment of localizationGO:00512342440.033
positive regulation of transportGO:005105020.033
muscle structure developmentGO:00610611960.033
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.033
Zebrafish Mouse Worm
ectodermal placode morphogenesisGO:0071697320.033
generation of neuronsGO:00486993850.033
Worm Fly
tube morphogenesisGO:00352393490.033
response to external stimulusGO:00096052640.032
Worm
immune system processGO:00023762410.031
signal transductionGO:00071654550.031
Zebrafish
cell proliferationGO:0008283800.031
inner ear morphogenesisGO:0042472630.031
sensory organ developmentGO:00074233930.031
Zebrafish
gland developmentGO:00487321430.031
Zebrafish Mouse
skeletal muscle fiber developmentGO:0048741350.031
single organism nuclear importGO:190259330.031
regulation of establishment of protein localizationGO:007020140.030
angiogenesisGO:00015251580.030
otic vesicle formationGO:0030916270.030
hard palate developmentGO:006002240.030
regulation of signalingGO:00230512350.030
myotube differentiationGO:0014902450.030
phagocytosis engulfmentGO:000691110.030
pigmentationGO:0043473850.030
digestive tract morphogenesisGO:00485462310.030
cellular modified amino acid metabolic processGO:000657530.029
neural crest cell migrationGO:0001755420.029
cell fate commitmentGO:0045165990.029
Mouse
transportGO:00068102200.029
nuclear importGO:005117030.029
response to chemicalGO:00422213200.029
Worm
wound healingGO:0042060900.028
regulation of tube sizeGO:003515020.028
mesenchyme developmentGO:00604851270.028
response to drugGO:004249330.028
positive regulation of protein complex assemblyGO:003133420.027
regulation of stem cell proliferationGO:007209120.027
cell fate specificationGO:0001708680.027
embryonic pattern specificationGO:0009880440.027
mesenchymal cell developmentGO:0014031780.027
skin developmentGO:0043588540.027
positive regulation of macromolecule metabolic processGO:0010604930.027
Zebrafish Mouse Worm
diencephalon developmentGO:0021536580.027
Zebrafish Mouse
regulation of multicellular organismal developmentGO:20000262230.027
endocrine processGO:005088620.026
negative regulation of macromolecule biosynthetic processGO:0010558480.026
cell differentiation in spinal cordGO:0021515400.026
pituitary gland developmentGO:0021983160.025
Zebrafish Mouse
sympathetic nervous system developmentGO:004848530.025
negative regulation of cellular metabolic processGO:0031324770.025
glial cell migrationGO:000834730.025
ear morphogenesisGO:0042471640.025
negative regulation of rna biosynthetic processGO:1902679450.025
positive regulation of gene expressionGO:0010628710.025
Zebrafish Mouse Worm
stem cell differentiationGO:00488631170.025
regulation of nucleocytoplasmic transportGO:004682220.025
regulation of carbohydrate metabolic processGO:000610940.025
anterior posterior pattern specificationGO:00099521520.024
protein polymerizationGO:005125840.024
striated muscle cell differentiationGO:00511461290.024
cell motilityGO:00488702440.024
axon ensheathment in central nervous systemGO:003229120.024
cell substrate adhesionGO:003158940.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
Zebrafish Mouse Rat Worm
stem cell divisionGO:001714510.024
b cell differentiationGO:003018310.023
regulation of canonical wnt signaling pathwayGO:0060828340.023
regulation of endodermal cell differentiationGO:1903224150.023
cell morphogenesisGO:00009022890.023
Worm Fly
small molecule metabolic processGO:0044281770.023
forebrain developmentGO:0030900960.023
Zebrafish Mouse
positive regulation of reproductive processGO:200024320.022
regulation of oocyte developmentGO:006028130.022
regulation of bindingGO:005109830.022
chemical homeostasisGO:0048878490.022
cellular carbohydrate metabolic processGO:004426240.022
positive regulation of protein polymerizationGO:003227320.022
regulation of dna replicationGO:000627530.022
wnt signaling pathwayGO:0016055800.022
transcription dna templatedGO:00063511810.022
Zebrafish Mouse Rat Worm
neuroblast proliferationGO:000740520.022
sequestering of metal ionGO:005123830.022
hormone transportGO:000991420.022
regulation of autophagyGO:001050630.021
positive regulation of biosynthetic processGO:0009891680.021
Zebrafish Mouse Worm
cellular amino acid metabolic processGO:000652070.021
female sex differentiationGO:004666040.021
embryonic viscerocranium morphogenesisGO:0048703520.021
Zebrafish
positive regulation of transcription dna templatedGO:0045893570.021
Zebrafish Mouse Worm
autonomic nervous system developmentGO:0048483190.021
regulation of wnt signaling pathwayGO:0030111530.020
regulation of organ growthGO:004662030.020
negative regulation of gene expressionGO:0010629650.020
regulation of neural precursor cell proliferationGO:200017730.020
system processGO:00030081850.020
Zebrafish
mononuclear cell proliferationGO:003294310.020
endocrine hormone secretionGO:006098620.020
cellular component assemblyGO:00226071700.020
skeletal system developmentGO:00015011810.020
Zebrafish Mouse
regulation of cell activationGO:005086510.020
g protein coupled receptor signaling pathwayGO:0007186740.020
camera type eye developmentGO:00430102220.020
Zebrafish
myotube cell developmentGO:0014904350.020
morphogenesis of an epitheliumGO:00020093330.020
Zebrafish
skeletal system morphogenesisGO:00487051020.020
Zebrafish
ear developmentGO:00435831270.020
neural plate anterior posterior regionalizationGO:002199980.020
actin filament polymerizationGO:003004120.020
regulation of locomotionGO:0040012550.019
Worm
small molecule catabolic processGO:004428230.019
endocrine system developmentGO:0035270650.019
Zebrafish Mouse
spinal cord motor neuron differentiationGO:0021522260.019
regulation of reproductive processGO:200024140.019
catechol containing compound metabolic processGO:000971220.019
catecholamine metabolic processGO:000658420.019
epidermal cell differentiationGO:0009913360.019
single organism biosynthetic processGO:0044711710.018
protein localization to nucleusGO:003450430.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
regulation of metal ion transportGO:001095940.018
enteric nervous system developmentGO:0048484120.018
neuron differentiationGO:00301823530.018
Worm Fly
cellular amine metabolic processGO:004410620.018
hatching gland developmentGO:004878530.018
type b pancreatic cell developmentGO:000332340.018
adult behaviorGO:003053420.018
endodermal cell differentiationGO:0035987190.018
positive regulation of catabolic processGO:000989640.018
reproductive processGO:0022414400.018
maintenance of locationGO:005123540.018
epidermal cell fate specificationGO:000995740.018
cell cycle g1 s phase transitionGO:004484310.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
blood coagulationGO:0007596120.017
lipid storageGO:001991510.017
regulation of signal transductionGO:00099662250.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
gastrulationGO:00073692080.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
regulation of anatomical structure morphogenesisGO:00226031300.017
regulation of protein targetingGO:190353320.017
multi organism processGO:00517041340.017
positive regulation of cellular catabolic processGO:003133130.017
positive regulation of epithelial cell proliferationGO:005067910.017
regulation of response to stimulusGO:00485832690.016
positive regulation of cellular carbohydrate metabolic processGO:001067610.016
cranial ganglion developmentGO:006155030.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of skeletal muscle tissue developmentGO:004864140.016
cell proliferation in hindbrainGO:002153440.016
embryonic digestive tract developmentGO:004856640.016
negative regulation of protein phosphorylationGO:000193340.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
negative regulation of biosynthetic processGO:0009890550.016
regulation of protein localization to nucleusGO:190018020.016
phosphate containing compound metabolic processGO:00067961080.016
lymphangiogenesisGO:0001946250.016
female gonad developmentGO:000858540.016
developmental programmed cell deathGO:001062340.016
autophagyGO:000691440.016
positive regulation of cellular component biogenesisGO:004408930.016
negative regulation of metabolic processGO:0009892860.016
central nervous system neuron differentiationGO:0021953740.016
establishment of localization in cellGO:0051649770.016
axonogenesisGO:00074091520.016
Worm
signal transduction in absence of ligandGO:003803410.015
regulation of protein polymerizationGO:003227120.015
response to radiationGO:0009314510.015
growthGO:00400071740.015
myelin assemblyGO:003228810.015
cell migrationGO:00164772370.015
retina development in camera type eyeGO:00600411460.015
positive regulation of carbohydrate metabolic processGO:004591310.015
lymph vessel developmentGO:0001945270.015
mesoderm developmentGO:0007498880.015
Zebrafish
zymogen activationGO:003163830.015
neural crest cell developmentGO:0014032620.015
g1 s transition of mitotic cell cycleGO:000008210.015
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
regulation of cell differentiationGO:00455951420.015
response to foodGO:003209410.015
heart morphogenesisGO:00030071560.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
positive regulation of epithelial cell differentiationGO:003085820.015
ectodermal placode formationGO:0060788260.015
positive regulation of stem cell proliferationGO:200064810.014
central nervous system myelin formationGO:003228910.014
carboxylic acid catabolic processGO:004639530.014
cell part morphogenesisGO:00329902460.014
Worm Fly
regulation of cell shapeGO:000836010.014
determination of heart left right asymmetryGO:00613711170.014
epidermis developmentGO:0008544480.014
skeletal muscle tissue developmentGO:0007519670.014
Mouse
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.014
neuron fate specificationGO:0048665200.014
eye developmentGO:00016542770.014
Zebrafish
negative regulation of macromolecule metabolic processGO:0010605760.014
blood circulationGO:0008015870.014
Zebrafish
positive regulation of cellular metabolic processGO:0031325940.014
Zebrafish Mouse Worm
positive regulation of dna metabolic processGO:005105410.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
Worm Fly
regulation of protein catabolic processGO:004217610.014
neural crest cell differentiationGO:0014033720.014
internal peptidyl lysine acetylationGO:001839320.014
lipid homeostasisGO:005508830.014
negative regulation of kinase activityGO:003367340.014
amine metabolic processGO:000930820.013
single organism organelle organizationGO:19025891990.013
cellular response to starvationGO:000926710.013
membrane invaginationGO:001032410.013
regulation of cell morphogenesis involved in differentiationGO:0010769380.013
cellular protein catabolic processGO:004425740.013
insulin like growth factor receptor signaling pathwayGO:004800940.013
deathGO:00162651210.013
adenohypophysis developmentGO:0021984150.013
Zebrafish
gastrulation with mouth forming secondGO:0001702440.013
circulatory system processGO:0003013870.013
Zebrafish
heart developmentGO:00075073130.013
Zebrafish
regulation of cellular amine metabolic processGO:003323800.013
actin polymerization or depolymerizationGO:000815420.013
regulation of growth rateGO:004000910.013
ventricular cardiac muscle tissue morphogenesisGO:005501020.013
transmission of nerve impulseGO:0019226190.013
glycerolipid biosynthetic processGO:004501710.013
regulation of blood vessel sizeGO:005088020.013
cell projection organizationGO:00300302840.013
Worm Fly
negative regulation of protein kinase activityGO:000646940.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
organic hydroxy compound metabolic processGO:1901615160.013
cellular response to endogenous stimulusGO:0071495680.013
embryonic limb morphogenesisGO:003032620.012
Mouse
neuron projection morphogenesisGO:00488121610.012
Worm Fly
response to uvGO:000941130.012
lateral line ganglion developmentGO:004889020.012
alcohol biosynthetic processGO:004616520.012
ventricular cardiac muscle tissue developmentGO:000322930.012
negative regulation of nucleic acid templated transcriptionGO:1903507450.012
single organism transportGO:00447652060.012
lymphocyte proliferationGO:004665110.012
ameboidal type cell migrationGO:00016671430.012
long chain fatty acid metabolic processGO:000167610.012
otic vesicle morphogenesisGO:0071600340.012
regulation of vasculature developmentGO:1901342330.012
regulation of carbohydrate biosynthetic processGO:004325510.012
cell cell signaling involved in cell fate commitmentGO:0045168120.012
neuroepithelial cell differentiationGO:0060563260.012
cellular response to extracellular stimulusGO:003166820.012
otic placode formationGO:0043049230.012
cell surface receptor signaling pathwayGO:00071663250.012
development of primary female sexual characteristicsGO:004654540.012
regulation of angiogenesisGO:0045765260.012
central nervous system myelinationGO:002201020.012
epibolyGO:0090504410.012
spermatid differentiationGO:004851520.012
positive regulation of mesenchymal cell proliferationGO:000205310.012
protein acetylationGO:000647320.012
epithelial cell differentiationGO:00308551160.012
single organism localizationGO:19025782250.012
organonitrogen compound metabolic processGO:1901564740.012
regulation of cell communicationGO:00106462320.012
fatty acid biosynthetic processGO:000663340.012
phenol containing compound biosynthetic processGO:004618940.012
regulation of gastrulationGO:0010470240.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
positive regulation of cell adhesionGO:004578510.012
connective tissue developmentGO:0061448990.012
Mouse
striated muscle tissue developmentGO:00147061100.012
Mouse
brain developmentGO:00074202930.011
Zebrafish Mouse
proteasomal protein catabolic processGO:001049820.011
muscle organ developmentGO:00075171010.011
Mouse
cellular response to chemical stimulusGO:00708871570.011
head developmentGO:00603223030.011
Zebrafish Mouse
positive regulation of rna biosynthetic processGO:1902680570.011
Zebrafish Mouse Worm
b cell activationGO:004211320.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
formation of primary germ layerGO:0001704620.011
organophosphate biosynthetic processGO:0090407230.011
sprouting angiogenesisGO:0002040530.011
positive regulation of multi organism processGO:004390230.011
regulation of endodermal cell fate specificationGO:0042663150.011
glial cell developmentGO:0021782200.011
carbohydrate biosynthetic processGO:001605110.011
pigment cell differentiationGO:0050931380.011
neuron neuron synaptic transmissionGO:000727010.011
mesenchymal cell differentiationGO:0048762870.011
regulation of epidermis developmentGO:004568220.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
cellular response to external stimulusGO:007149620.011
central nervous system developmentGO:00074173870.011
Zebrafish Mouse
protein secretionGO:000930610.011
positive regulation of neuron deathGO:190121610.011
carbohydrate homeostasisGO:003350010.011
ectodermal placode developmentGO:0071696370.011
neuron projection developmentGO:00311751800.011
Worm Fly
negative regulation of cell cycleGO:0045786140.011
endoderm formationGO:0001706290.011
cell cycle arrestGO:000705010.011
muscle fiber developmentGO:0048747520.011
neuronal action potentialGO:0019228180.011
negative regulation of leukocyte differentiationGO:190210610.010
organic acid catabolic processGO:001605430.010
neural plate pattern specificationGO:0060896120.010
negative regulation of transcription dna templatedGO:0045892450.010
negative regulation of neural precursor cell proliferationGO:200017810.010
fin regenerationGO:0031101510.010
cell matrix adhesionGO:000716040.010
primary neural tube formationGO:001402010.010
negative regulation of rna metabolic processGO:0051253480.010
single organism membrane fusionGO:004480120.010
regulation of cellular amino acid metabolic processGO:000652100.010
columnar cuboidal epithelial cell differentiationGO:0002065380.010
protein acylationGO:004354330.010
regulation of cytokine productionGO:000181730.010
inositol lipid mediated signalingGO:004801720.010

pitx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.069
Human
musculoskeletal system diseaseDOID:1700.018
Human
nervous system diseaseDOID:86300.015
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.011