Danio rerio

29 known processes

ptges

prostaglandin E synthase

(Aliases: zgc:110052,mpges)

ptges biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
localization of cellGO:00516742440.298
regulation of protein localization to nucleusGO:190018020.290
negative regulation of biological processGO:00485193040.256
Mouse
nuclear transportGO:005116940.249
cell migration involved in gastrulationGO:0042074790.217
signal transductionGO:00071654550.169
single organism nuclear importGO:190259330.161
chordate embryonic developmentGO:00430092710.153
protein import into nucleusGO:000660630.149
agingGO:000756820.147
nuclear importGO:005117030.140
appendage developmentGO:0048736800.140
larval developmentGO:000216420.138
cell motilityGO:00488702440.138
regulation of response to stimulusGO:00485832690.137
cell migrationGO:00164772370.135
brain developmentGO:00074202930.130
regulation of protein transportGO:005122330.130
regulation of establishment of protein localizationGO:007020140.128
nucleocytoplasmic transportGO:000691340.127
locomotionGO:00400113130.124
response to lipidGO:0033993600.124
establishment of protein localization to organelleGO:007259440.120
neuron developmentGO:00486662620.117
response to chemicalGO:00422213200.111
regulation of biological qualityGO:00650082630.110
protein importGO:001703830.107
regulation of cytokine productionGO:000181730.102
embryonic organ morphogenesisGO:00485622740.099
regulation of intracellular protein transportGO:003315730.095
regulation of cell communicationGO:00106462320.094
response to organic substanceGO:00100331530.094
cell part morphogenesisGO:00329902460.091
regulation of epithelial cell proliferationGO:005067830.086
negative regulation of response to stimulusGO:00485851040.084
cell projection organizationGO:00300302840.082
protein localization to nucleusGO:003450430.081
regulation of signal transductionGO:00099662250.081
negative regulation of protein transportGO:005122430.078
regulation of protein import into nucleusGO:004230620.076
regulation of extrinsic apoptotic signaling pathwayGO:200123630.076
cell projection morphogenesisGO:00488582440.075
protein targeting to nucleusGO:004474430.074
cellular macromolecule metabolic processGO:00442603910.074
positive regulation of cellular component biogenesisGO:004408930.073
regulation of cytoplasmic transportGO:190364940.072
ameboidal type cell migrationGO:00016671430.071
regionalizationGO:00030022740.069
regulation of protein targetingGO:190353320.069
tube morphogenesisGO:00352393490.069
regulation of nucleocytoplasmic transportGO:004682220.067
regulation of signalingGO:00230512350.065
regulation of synapse assemblyGO:005196330.062
cellular protein catabolic processGO:004425740.060
cell morphogenesisGO:00009022890.059
nitrogen compound metabolic processGO:00068073190.059
axonal defasciculationGO:000741420.058
response to woundingGO:00096111160.058
gastrulationGO:00073692080.057
cell morphogenesis involved in neuron differentiationGO:00486671630.057
embryo development ending in birth or egg hatchingGO:00097922710.056
wound healingGO:0042060900.054
cell surface receptor signaling pathwayGO:00071663250.054
positive regulation of cell cycleGO:004578730.053
multicellular organism growthGO:003526440.053
apoptotic signaling pathwayGO:0097190230.052
negative regulation of protein import into nucleusGO:004230820.051
neuron projection developmentGO:00311751800.050
response to oxygen containing compoundGO:1901700550.050
regulation of multicellular organismal processGO:00512392770.049
positive regulation of transportGO:005105020.049
regulation of synapse organizationGO:005080730.049
taxisGO:00423301090.048
positive regulation of inflammatory responseGO:005072910.048
apoptotic processGO:00069151160.048
cytokinesisGO:000091030.047
negative regulation of signalingGO:0023057960.047
regulation of tube sizeGO:003515020.047
proteolysis involved in cellular protein catabolic processGO:005160330.044
intracellular signal transductionGO:0035556850.044
response to stressGO:00069502630.044
negative regulation of signal transductionGO:0009968940.044
cellular nitrogen compound metabolic processGO:00346412900.043
protein acetylationGO:000647320.043
angiogenesisGO:00015251580.043
maintenance of locationGO:005123540.043
lateral inhibitionGO:004633110.041
biosynthetic processGO:00090582940.041
Human
cellular component disassemblyGO:002241110.040
regulation of multicellular organismal developmentGO:20000262230.039
heart developmentGO:00075073130.039
positive regulation of cell adhesionGO:004578510.038
cellular response to radiationGO:007147840.038
cell migration involved in heart developmentGO:0060973220.038
positive regulation of cellular catabolic processGO:003133130.037
cellular response to organic substanceGO:00713101050.037
response to vitaminGO:003327330.037
cellular component movementGO:00069283350.036
embryonic organ developmentGO:00485683810.036
regulation of cellular amine metabolic processGO:003323800.036
developmental growthGO:00485891660.036
cellular component biogenesisGO:00440851780.036
cellular response to chemical stimulusGO:00708871570.036
meiotic cell cycle processGO:190304630.036
muscle structure developmentGO:00610611960.036
gene silencing by mirnaGO:003519530.036
organelle organizationGO:00069962270.035
regulation of cellular component movementGO:0051270550.035
regulation of catenin import into nucleusGO:003541220.035
heart morphogenesisGO:00030071560.035
neuron projection morphogenesisGO:00488121610.035
single organism organelle organizationGO:19025891990.034
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.034
rho protein signal transductionGO:000726650.034
response to amino acidGO:004320020.034
central nervous system developmentGO:00074173870.034
regulation of axonogenesisGO:0050770320.034
proteasomal protein catabolic processGO:001049820.033
ossificationGO:0001503230.033
response to steroid hormoneGO:0048545350.033
single organism localizationGO:19025782250.033
protein metabolic processGO:00195381830.032
response to external stimulusGO:00096052640.032
regulation of multicellular organism growthGO:004001440.032
developmental growth involved in morphogenesisGO:0060560860.032
phagocytosisGO:000690930.032
regulation of dna replicationGO:000627530.032
regulation of reproductive processGO:200024140.031
cell recognitionGO:0008037190.031
wnt signaling pathwayGO:0016055800.031
extrinsic apoptotic signaling pathwayGO:009719130.031
cellular component morphogenesisGO:00329893360.031
organic substance biosynthetic processGO:19015762890.031
Human
response to nutrientGO:000758430.031
somitogenesisGO:0001756870.031
positive regulation of locomotionGO:0040017140.031
establishment of localizationGO:00512342440.030
somite developmentGO:0061053960.030
response to corticosteroidGO:003196010.030
dendrite morphogenesisGO:004881350.030
regulation of inflammatory responseGO:005072720.030
endochondral bone growthGO:000341620.030
cytoskeleton dependent cytokinesisGO:006164030.030
cartilage developmentGO:0051216960.030
regulation of cellular amino acid metabolic processGO:000652100.029
digestive tract mesoderm developmentGO:000750210.029
cellular biosynthetic processGO:00442492860.029
Human
digestive system developmentGO:00551232890.029
organism emergence from protective structureGO:007168440.029
sensory perception of mechanical stimulusGO:0050954160.029
positive regulation of biological processGO:00485182530.029
establishment of localization in cellGO:0051649770.029
single organismal cell cell adhesionGO:0016337290.029
amine metabolic processGO:000930820.029
peptidyl lysine acetylationGO:001839420.028
carboxylic acid metabolic processGO:0019752220.028
Human Mouse
organic acid metabolic processGO:0006082310.028
Human Mouse
negative regulation of metabolic processGO:0009892860.028
guanosine containing compound catabolic processGO:190106920.028
stem cell maintenanceGO:001982740.028
neuron differentiationGO:00301823530.028
organelle fusionGO:004828430.028
transportGO:00068102200.028
positive regulation of blood circulationGO:190352420.028
keratinocyte differentiationGO:003021600.027
response to monosaccharideGO:003428430.027
cell morphogenesis involved in differentiationGO:00009041950.027
negative regulation of intracellular protein transportGO:009031730.027
oxoacid metabolic processGO:0043436310.027
Human Mouse
sensory organ developmentGO:00074233930.027
notch signaling pathwayGO:0007219350.027
response to hexoseGO:000974630.027
head developmentGO:00603223030.027
chromosome organizationGO:0051276310.026
appendage morphogenesisGO:0035107560.026
skeletal system developmentGO:00015011810.026
i kappab kinase nf kappab signalingGO:000724940.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
mesoderm developmentGO:0007498880.026
generation of neuronsGO:00486993850.026
embryonic limb morphogenesisGO:003032620.025
regulation of cell activationGO:005086510.025
negative regulation of reproductive processGO:200024230.025
growthGO:00400071740.024
anterior posterior pattern specificationGO:00099521520.024
gene silencing by rnaGO:003104740.024
regulation of protein catabolic processGO:004217610.024
negative regulation of epithelial cell proliferationGO:005068010.024
positive regulation of cytokine productionGO:000181920.024
regulation of bindingGO:005109830.024
tissue migrationGO:0090130370.024
deathGO:00162651210.023
regulation of nucleoside metabolic processGO:000911820.023
developmental cell growthGO:0048588520.023
regulation of cell migrationGO:0030334400.023
cellular response to stressGO:0033554620.023
internal protein amino acid acetylationGO:000647520.023
regulation of cellular component organizationGO:0051128860.023
small gtpase mediated signal transductionGO:000726480.023
cellular amine metabolic processGO:004410620.022
meiotic nuclear divisionGO:000712640.022
protein complex localizationGO:003150310.022
epithelial cell migrationGO:0010631250.022
regulation of locomotionGO:0040012550.022
negative regulation of cell communicationGO:0010648960.022
regulation of anatomical structure sizeGO:0090066330.022
gtp metabolic processGO:004603940.022
cellular response to external stimulusGO:007149620.022
formation of primary germ layerGO:0001704620.022
gland developmentGO:00487321430.021
regulation of gene expression epigeneticGO:0040029110.021
regulation of muscle contractionGO:000693730.021
negative regulation of gene expressionGO:0010629650.021
organic cyclic compound metabolic processGO:19013603010.021
heterocycle metabolic processGO:00464832900.021
cellular component assemblyGO:00226071700.021
central nervous system projection neuron axonogenesisGO:0021952150.021
negative regulation of cellular processGO:00485232830.021
Mouse
cellular response to nutrient levelsGO:003166920.021
regulation of gtp catabolic processGO:003312420.021
regulation of cell cycleGO:0051726520.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.021
glial cell migrationGO:000834730.021
cell cycleGO:0007049930.021
response to carbohydrateGO:000974330.021
erythrocyte homeostasisGO:0034101550.020
regulation of blood pressureGO:000821710.020
endocardial cushion formationGO:000327220.020
protein acylationGO:004354330.020
regulation of calcium ion transportGO:005192420.020
positive regulation of catabolic processGO:000989640.020
axonogenesisGO:00074091520.020
stem cell divisionGO:001714510.020
response to uvGO:000941130.020
negative regulation of nucleocytoplasmic transportGO:004682320.019
small molecule metabolic processGO:0044281770.019
Human Mouse
internal peptidyl lysine acetylationGO:001839320.019
regulation of purine nucleotide catabolic processGO:003312120.019
organonitrogen compound metabolic processGO:1901564740.019
macromolecule modificationGO:00434121110.019
cell growthGO:0016049570.019
negative regulation of cytoplasmic transportGO:190365020.019
response to glucocorticoidGO:005138410.019
protein complex subunit organizationGO:0071822460.019
chemotaxisGO:00069351040.019
regulation of cell sizeGO:0008361290.019
regulation of apoptotic processGO:0042981980.019
regulation of gene expressionGO:00104682650.019
tissue regenerationGO:0042246740.019
single organism reproductive processGO:0044702400.018
negative regulation of multicellular organismal processGO:0051241690.018
phosphorus metabolic processGO:00067931090.018
negative regulation of macromolecule metabolic processGO:0010605760.018
macromolecule biosynthetic processGO:00090592270.018
blood vessel developmentGO:00015682460.018
regulation of rna metabolic processGO:00512522240.018
gtp catabolic processGO:000618420.018
gene silencingGO:001645840.018
negative regulation of defense responseGO:003134820.018
regulation of response to external stimulusGO:0032101310.018
negative regulation of intracellular transportGO:003238730.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
response to drugGO:004249330.018
negative regulation of cellular metabolic processGO:0031324770.018
regulation of cellular protein catabolic processGO:190336210.017
fin morphogenesisGO:0033334530.017
vasculature developmentGO:00019442780.017
circulatory system processGO:0003013870.017
regulation of rna biosynthetic processGO:20011412130.017
segmentationGO:0035282970.017
cell cycle g1 s phase transitionGO:004484310.017
guanosine containing compound metabolic processGO:190106840.017
negative chemotaxisGO:005091910.017
growth plate cartilage developmentGO:000341720.017
protein secretionGO:000930610.017
protein modification processGO:00362111000.017
positive regulation of nucleotide catabolic processGO:003081310.017
fatty acid biosynthetic processGO:000663340.017
Human
homeostatic processGO:00425921420.017
regulation of intracellular signal transductionGO:1902531570.017
positive regulation of response to stimulusGO:0048584800.017
transcription from rna polymerase ii promoterGO:0006366800.017
sensory perceptionGO:0007600390.017
cellular amino acid metabolic processGO:000652070.017
lipid storageGO:001991510.017
cellular response to retinoic acidGO:007130010.017
catenin import into nucleusGO:003541120.017
blood vessel morphogenesisGO:00485142160.017
olfactory bulb developmentGO:002177240.017
axon developmentGO:00615641660.017
epidermis developmentGO:0008544480.017
defense responseGO:0006952470.017
digestive tract morphogenesisGO:00485462310.017
cellular protein modification processGO:00064641000.016
positive regulation of developmental processGO:0051094500.016
response to abiotic stimulusGO:00096281220.016
regulation of metabolic processGO:00192223590.016
olfactory lobe developmentGO:002198840.016
positive regulation of chromatin modificationGO:190331010.016
hatchingGO:003518840.016
single organism cellular localizationGO:1902580460.016
regulation of cellular biosynthetic processGO:00313262450.016
myeloid cell homeostasisGO:0002262560.016
smooth muscle contractionGO:000693920.016
muscle fiber developmentGO:0048747520.016
nitric oxide biosynthetic processGO:000680920.016
dendrite developmentGO:001635890.016
negative regulation of cytokine productionGO:000181810.016
positive regulation of secretionGO:005104710.016
regulation of protein complex assemblyGO:004325430.016
retinal ganglion cell axon guidanceGO:0031290350.016
regulation of nitrogen compound metabolic processGO:00511712510.016
cell cell signaling involved in cell fate commitmentGO:0045168120.016
striated muscle tissue developmentGO:00147061100.016
exocrine system developmentGO:0035272280.016
negative regulation of rna biosynthetic processGO:1902679450.016
cellular protein metabolic processGO:00442671290.015
response to molecule of bacterial originGO:0002237140.015
dorsal ventral pattern formationGO:00099531250.015
fin developmentGO:0033333770.015
nucleobase containing compound metabolic processGO:00061392740.015
positive regulation of cell communicationGO:0010647560.015
axon guidanceGO:0007411860.015
positive regulation of cell activationGO:005086710.015
negative regulation of biosynthetic processGO:0009890550.015
gene expressionGO:00104672520.015
regulation of nucleotide catabolic processGO:003081120.015
nitric oxide metabolic processGO:004620920.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
negative regulation of chemotaxisGO:005092240.015
regulation of localizationGO:00328791040.015
central nervous system neuron axonogenesisGO:0021955180.015
regulation of blood circulationGO:1903522320.015
tube closureGO:006060610.015
regulation of cell shapeGO:000836010.014
positive regulation of gtpase activityGO:004354710.014
biological adhesionGO:0022610400.014
cellular response to xenobiotic stimulusGO:0071466350.014
apical junction assemblyGO:004329710.014
regulation of response to nutrient levelsGO:003210710.014
ubiquitin dependent protein catabolic processGO:000651130.014
positive regulation of ras protein signal transductionGO:004657910.014
morphogenesis of an epitheliumGO:00020093330.014
regulation of gtpase activityGO:004308720.014
tissue remodelingGO:004877140.014
regulation of cell projection organizationGO:0031344440.014
mitochondrion organizationGO:000700540.014
specification of symmetryGO:00097992040.014
regulation of chromosome segregationGO:005198310.014
positive regulation of stress activated mapk cascadeGO:003287430.014
reactive oxygen species biosynthetic processGO:190340910.014
cellular response to light stimulusGO:007148240.014
cell cell signalingGO:0007267520.014
multicellular organismal homeostasisGO:0048871290.014
negative regulation of synapse assemblyGO:005196420.014
cellular response to oxygen levelsGO:007145310.014
g1 s transition of mitotic cell cycleGO:000008210.014
germ line stem cell maintenanceGO:003071820.014
regulation of rho protein signal transductionGO:003502320.014
nucleic acid metabolic processGO:00903042440.014
bone remodelingGO:004684920.014
response to biotic stimulusGO:0009607970.014
fin regenerationGO:0031101510.014
response to radiationGO:0009314510.014
heterocycle biosynthetic processGO:00181302150.014
positive regulation of gtp catabolic processGO:003312610.014
regulation of cell deathGO:00109411030.014
cell deathGO:00082191210.013
regulation of reactive oxygen species metabolic processGO:200037720.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of cellular ketone metabolic processGO:001056570.013
nucleobase containing compound biosynthetic processGO:00346542050.013
positive regulation of cellular component movementGO:0051272110.013
regulation of biosynthetic processGO:00098892500.013
negative regulation of apoptotic processGO:0043066550.013
multi organism processGO:00517041340.013
positive regulation of cell motilityGO:2000147110.013
cellular response to hypoxiaGO:007145610.013
cellular aromatic compound metabolic processGO:00067252950.013
cellular ketone metabolic processGO:0042180110.013
axon midline choice point recognitionGO:001619940.013
regulation of programmed cell deathGO:00430671010.013
regulation of defense responseGO:0031347140.013
regulation of organelle assemblyGO:190211540.013
modification dependent macromolecule catabolic processGO:004363230.013
reactive nitrogen species metabolic processGO:200105700.013
regulation of response to extracellular stimulusGO:003210410.013
photoreceptor cell differentiationGO:0046530550.013
phosphate containing compound metabolic processGO:00067961080.013
regulation of cytoskeleton organizationGO:0051493110.013
convergent extensionGO:00600261180.013
regulation of cell differentiationGO:00455951420.013
system processGO:00030081850.013
cell migration to the midline involved in heart developmentGO:0003318120.013
cartilage morphogenesisGO:0060536130.013
negative regulation of nuclear divisionGO:005178430.013
regulation of cell motilityGO:2000145460.012
cellular response to lipidGO:0071396390.012
negative regulation of axon extensionGO:003051770.012
single organism metabolic processGO:00447102170.012
Human Mouse
negative regulation of wnt signaling pathwayGO:0030178300.012
negative regulation of transcription dna templatedGO:0045892450.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
endoderm formationGO:0001706290.012
muscle tissue developmentGO:00605371100.012
cell cycle arrestGO:000705010.012
cellular response to decreased oxygen levelsGO:003629410.012
positive regulation of epithelial cell migrationGO:001063420.012
cellular response to dna damage stimulusGO:0006974240.012
b cell activationGO:004211320.012
positive regulation of chromosome organizationGO:200125210.012
phagocytosis engulfmentGO:000691110.012
programmed cell deathGO:00125011190.012
regulation of canonical wnt signaling pathwayGO:0060828340.012
regulation of establishment of protein localization to plasma membraneGO:009000310.012
mitotic dna integrity checkpointGO:004477440.012
macromolecule deacylationGO:009873230.012
pectoral fin developmentGO:0033339500.012
fat soluble vitamin metabolic processGO:000677540.012
response to acid chemicalGO:0001101170.012
cellular response to endogenous stimulusGO:0071495680.012
sensory perception of painGO:001923310.012
regulation of blood vessel sizeGO:005088020.012
formation of anatomical boundaryGO:0048859140.012
response to glucoseGO:000974930.012
positive regulation of histone modificationGO:003105810.012
rna metabolic processGO:00160702190.012
epithelium migrationGO:0090132250.012
macromolecular complex subunit organizationGO:0043933740.012
cellular macromolecule localizationGO:0070727210.012
response to bacteriumGO:0009617580.011
regenerationGO:0031099910.011
urogenital system developmentGO:0001655970.011
response to external biotic stimulusGO:0043207970.011
positive regulation of protein complex assemblyGO:003133420.011
single organism biosynthetic processGO:0044711710.011
Human
signal transduction in absence of ligandGO:003803410.011
regulation of metal ion transportGO:001095940.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
cellular carbohydrate metabolic processGO:004426240.011
regulation of receptor mediated endocytosisGO:004825940.011
modification dependent protein catabolic processGO:001994130.011
coagulationGO:0050817130.011
mesenchyme developmentGO:00604851270.011
actin filament polymerizationGO:003004120.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
positive regulation of map kinase activityGO:004340630.011
regulation of dna damage response signal transduction by p53 class mediatorGO:004351640.011
peptide transportGO:001583310.011
long chain fatty acid metabolic processGO:000167610.011
mitotic cell cycleGO:0000278640.011
mitotic cytokinesisGO:000028130.011
negative regulation of axon extension involved in axon guidanceGO:004884310.011
homeostasis of number of cellsGO:0048872620.011
embryonic camera type eye morphogenesisGO:0048596190.011
leukocyte migrationGO:0050900150.011
cell projection assemblyGO:0030031640.011
negative regulation of multi organism processGO:004390130.011
regulation of histone deacetylationGO:003106320.011
organic cyclic compound biosynthetic processGO:19013622230.011
leukocyte homeostasisGO:000177620.011
rna biosynthetic processGO:00327741810.011
posttranscriptional gene silencing by rnaGO:003519430.011
axon extensionGO:0048675450.011
positive regulation of response to external stimulusGO:003210390.011
positive regulation of cytoskeleton organizationGO:005149530.010
heart contractionGO:0060047710.010
establishment of organelle localizationGO:0051656450.010
neuron projection extensionGO:1990138450.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
fatty acid transportGO:001590810.010
response to decreased oxygen levelsGO:0036293250.010
histone deacetylationGO:001657520.010
muscle cell differentiationGO:00426921390.010
positive regulation of protein deacetylationGO:009031210.010
carbohydrate derivative metabolic processGO:1901135610.010
regulation of cell migration involved in sprouting angiogenesisGO:009004930.010
cell agingGO:000756920.010
cell proliferationGO:0008283800.010
Mouse
cytoskeleton organizationGO:0007010960.010
positive regulation of jnk cascadeGO:004633030.010
positive regulation of endothelial cell migrationGO:001059520.010
regulation of response to stressGO:0080134360.010
ion transportGO:00068111140.010

ptges disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.019
organ system cancerDOID:005068600.017
musculoskeletal system diseaseDOID:1700.016
nervous system diseaseDOID:86300.016