Danio rerio

27 known processes

orc1

origin recognition complex, subunit 1

(Aliases: orc1l,zgc:55976,MGC55976,wu:fa11h08)

orc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic substance biosynthetic processGO:19015762890.577
Fly
mitotic dna integrity checkpointGO:004477440.458
cellular macromolecule biosynthetic processGO:00346452240.414
Fly
modification dependent protein catabolic processGO:001994130.403
cellular protein catabolic processGO:004425740.403
nucleobase containing compound metabolic processGO:00061392740.378
Fly
protein metabolic processGO:00195381830.376
cellular nitrogen compound metabolic processGO:00346412900.366
Fly
organic cyclic compound metabolic processGO:19013603010.328
Fly
regulation of metabolic processGO:00192223590.316
cellular macromolecule metabolic processGO:00442603910.303
Fly
heterocycle metabolic processGO:00464832900.298
Fly
nucleic acid metabolic processGO:00903042440.292
Fly
nucleobase containing compound biosynthetic processGO:00346542050.290
Fly
regulation of dna replicationGO:000627530.289
regulation of transcription dna templatedGO:00063552130.281
regulation of primary metabolic processGO:00800903110.278
cellular biosynthetic processGO:00442492860.274
Fly
cellular aromatic compound metabolic processGO:00067252950.271
Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.254
negative regulation of mitosisGO:004583930.248
aromatic compound biosynthetic processGO:00194382170.245
Fly
cellular nitrogen compound biosynthetic processGO:00442712180.231
Fly
biosynthetic processGO:00090582940.215
Fly
regulation of nitrogen compound metabolic processGO:00511712510.208
regulation of protein catabolic processGO:004217610.208
negative regulation of nuclear divisionGO:005178430.197
organic cyclic compound biosynthetic processGO:19013622230.196
Fly
gene expressionGO:00104672520.192
regulation of cellular metabolic processGO:00313233200.188
modification dependent macromolecule catabolic processGO:004363230.180
ubiquitin dependent protein catabolic processGO:000651130.175
regulation of cellular biosynthetic processGO:00313262450.170
chromatin modificationGO:0016568210.169
nitrogen compound metabolic processGO:00068073190.145
Fly
cellular component biogenesisGO:00440851780.141
positive regulation of metabolic processGO:00098931080.134
regulation of protein ubiquitinationGO:003139630.133
regulation of cellular macromolecule biosynthetic processGO:20001122220.132
rna metabolic processGO:00160702190.120
regulation of cell cycleGO:0051726520.120
regulation of nucleic acid templated transcriptionGO:19035062130.118
proteolysis involved in cellular protein catabolic processGO:005160330.117
positive regulation of biological processGO:00485182530.117
regulation of meiotic cell cycleGO:005144510.116
macromolecule biosynthetic processGO:00090592270.113
Fly
positive regulation of cell cycleGO:004578730.113
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.110
cellular protein metabolic processGO:00442671290.108
dna metabolic processGO:0006259270.107
Fly
regulation of macromolecule metabolic processGO:00602553170.102
negative regulation of mitotic cell cycleGO:0045930110.101
g2 dna damage checkpointGO:003157230.100
regulation of biosynthetic processGO:00098892500.099
regulation of gene expressionGO:00104682650.098
larval developmentGO:000216420.097
Worm
positive regulation of macromolecule metabolic processGO:0010604930.097
meiotic chromosome segregationGO:004513230.097
embryo development ending in birth or egg hatchingGO:00097922710.095
Worm
cellular component assemblyGO:00226071700.095
positive regulation of catabolic processGO:000989640.095
g2 m transition of mitotic cell cycleGO:000008640.094
signal transductionGO:00071654550.092
macromolecule modificationGO:00434121110.090
proteasomal protein catabolic processGO:001049820.090
dna biosynthetic processGO:007189730.088
Fly
positive regulation of cellular processGO:00485222010.084
rna biosynthetic processGO:00327741810.080
nucleic acid templated transcriptionGO:00976591810.078
single organism organelle organizationGO:19025891990.077
meiotic cell cycle processGO:190304630.076
immune system processGO:00023762410.075
positive regulation of cellular metabolic processGO:0031325940.074
microtubule cytoskeleton organization involved in mitosisGO:190285010.072
transcription dna templatedGO:00063511810.071
single organism biosynthetic processGO:0044711710.070
mitotic g2 m transition checkpointGO:004481830.070
cellular component morphogenesisGO:00329893360.069
regulation of organelle organizationGO:0033043290.068
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.066
mitotic cell cycle processGO:1903047480.066
double strand break repairGO:000630230.066
regulation of rna biosynthetic processGO:20011412130.066
protein modification processGO:00362111000.065
regulation of rna metabolic processGO:00512522240.064
regulation of biological qualityGO:00650082630.063
positive regulation of gene expressionGO:0010628710.062
centrosome duplicationGO:005129810.060
cell cycle g2 m phase transitionGO:004483940.059
response to stressGO:00069502630.058
chromatin organizationGO:0006325220.058
regulation of protein modification by small protein conjugation or removalGO:190332030.057
centrosome organizationGO:005129710.055
negative regulation of cellular processGO:00485232830.055
stem cell maintenanceGO:001982740.055
histone phosphorylationGO:001657220.054
cytokinesisGO:000091030.053
response to alkaloidGO:004327920.052
cellular catabolic processGO:0044248270.052
amine metabolic processGO:000930820.051
nuclear importGO:005117030.051
regulation of protein complex assemblyGO:004325430.051
cellular protein modification processGO:00064641000.050
agingGO:000756820.050
negative regulation of transcription dna templatedGO:0045892450.050
gland developmentGO:00487321430.050
negative regulation of metabolic processGO:0009892860.048
single organism metabolic processGO:00447102170.048
protein importGO:001703830.047
programmed cell deathGO:00125011190.047
cellular ketone metabolic processGO:0042180110.047
regulation of macromolecule biosynthetic processGO:00105562250.047
regulation of protein import into nucleusGO:004230620.047
cellular response to external stimulusGO:007149620.046
proteolysisGO:0006508380.045
establishment of localizationGO:00512342440.044
response to abiotic stimulusGO:00096281220.044
negative regulation of nitrogen compound metabolic processGO:0051172590.043
sex determinationGO:000753010.043
cell cycleGO:0007049930.043
mitotic cell cycle embryonicGO:004544820.043
negative regulation of cellular biosynthetic processGO:0031327550.043
cellular response to stressGO:0033554620.043
oocyte maturationGO:000155640.042
negative regulation of biological processGO:00485193040.042
developmental growthGO:00485891660.042
regulation of mitotic cell cycleGO:0007346250.042
establishment of protein localization to organelleGO:007259440.041
regulation of cytoplasmic transportGO:190364940.040
homeostatic processGO:00425921420.040
mitotic cell cycleGO:0000278640.040
g1 s transition of mitotic cell cycleGO:000008210.040
microtubule organizing center organizationGO:003102310.039
dna replication checkpointGO:000007610.038
positive regulation of nitrogen compound metabolic processGO:0051173690.037
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.036
centrosome cycleGO:000709810.036
multicellular organism growthGO:003526440.036
double strand break repair via homologous recombinationGO:000072410.036
mitotic dna damage checkpointGO:004477340.035
positive regulation of cellular catabolic processGO:003133130.035
negative regulation of nucleic acid templated transcriptionGO:1903507450.035
carboxylic acid metabolic processGO:0019752220.035
peptidyl threonine modificationGO:001821010.034
regulation of cell cycle phase transitionGO:190198780.034
regulation of protein targetingGO:190353320.034
negative regulation of chromosome organizationGO:200125110.034
deathGO:00162651210.033
transcription from rna polymerase ii promoterGO:0006366800.033
single organism nuclear importGO:190259330.033
growthGO:00400071740.033
regulation of establishment of protein localizationGO:007020140.033
response to light stimulusGO:0009416460.032
negative regulation of cytoplasmic transportGO:190365020.032
anterior posterior pattern specificationGO:00099521520.031
intra s dna damage checkpointGO:003157310.031
cell projection morphogenesisGO:00488582440.031
pancreas developmentGO:0031016840.031
negative regulation of macromolecule metabolic processGO:0010605760.031
regulation of cellular component organizationGO:0051128860.031
heterocycle biosynthetic processGO:00181302150.030
Fly
protein targeting to nucleusGO:004474430.030
positive regulation of rna metabolic processGO:0051254590.030
negative regulation of dna metabolic processGO:005105340.030
striated muscle cell developmentGO:00550021080.030
dna alkylationGO:000630580.029
transportGO:00068102200.029
regulation of proteolysisGO:0030162240.029
organelle assemblyGO:00709251100.029
peptidyl serine phosphorylationGO:001810510.029
regulation of dna metabolic processGO:0051052110.029
protein complex assemblyGO:0006461300.029
negative regulation of nucleobase containing compound metabolic processGO:0045934590.029
negative regulation of rna biosynthetic processGO:1902679450.029
single organism reproductive processGO:0044702400.029
Worm
protein polymerizationGO:005125840.028
heart developmentGO:00075073130.028
response to uvGO:000941130.028
regulation of cellular protein metabolic processGO:0032268520.028
phosphate containing compound metabolic processGO:00067961080.027
response to external stimulusGO:00096052640.027
cell morphogenesisGO:00009022890.027
negative regulation of cellular metabolic processGO:0031324770.027
cytoskeleton organizationGO:0007010960.027
maintenance of locationGO:005123540.027
organelle organizationGO:00069962270.027
positive regulation of histone modificationGO:003105810.026
negative regulation of biosynthetic processGO:0009890550.026
regulation of nucleocytoplasmic transportGO:004682220.026
regulation of cellular ketone metabolic processGO:001056570.026
cell cycle g1 s phase transitionGO:004484310.026
central nervous system developmentGO:00074173870.026
nucleocytoplasmic transportGO:000691340.025
response to chemicalGO:00422213200.025
regulation of cell cycle processGO:0010564200.025
positive regulation of chromatin modificationGO:190331010.025
intracellular signal transductionGO:0035556850.025
macromolecule catabolic processGO:0009057150.024
histone modificationGO:0016570200.024
positive regulation of rna biosynthetic processGO:1902680570.024
macromolecular complex subunit organizationGO:0043933740.024
positive regulation of protein complex assemblyGO:003133420.024
regulation of response to stimulusGO:00485832690.024
regulation of mitosisGO:000708890.024
positive regulation of chromosome organizationGO:200125210.024
cellular amino acid metabolic processGO:000652070.024
developmental programmed cell deathGO:001062340.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.024
protein complex biogenesisGO:0070271300.023
gene silencingGO:001645840.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of cellular protein catabolic processGO:190336210.023
peptidyl serine modificationGO:001820920.023
organic acid metabolic processGO:0006082310.023
negative regulation of gene expressionGO:0010629650.023
cellular amine metabolic processGO:004410620.023
negative regulation of macromolecule biosynthetic processGO:0010558480.023
positive regulation of molecular functionGO:0044093330.023
response to biotic stimulusGO:0009607970.023
cellular macromolecule catabolic processGO:0044265120.023
response to organic substanceGO:00100331530.023
apoptotic processGO:00069151160.022
generation of neuronsGO:00486993850.022
immune system developmentGO:00025201910.022
phosphorylationGO:0016310690.022
cellular response to organic substanceGO:00713101050.022
regulation of protein localization to nucleusGO:190018020.022
meiosis iGO:000712710.021
cellular response to endogenous stimulusGO:0071495680.021
regulation of cellular amino acid metabolic processGO:000652100.021
multi organism processGO:00517041340.021
neuron developmentGO:00486662620.021
negative regulation of cell cycle processGO:001094890.021
cellular process involved in reproduction in multicellular organismGO:0022412280.021
immunoglobulin mediated immune responseGO:001606430.020
dna methylationGO:000630680.020
guanosine containing compound catabolic processGO:190106920.020
chordate embryonic developmentGO:00430092710.020
negative regulation of dna replicationGO:000815620.020
macromolecular complex assemblyGO:0065003350.020
nuclear transportGO:005116940.020
stem cell fate commitmentGO:004886510.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
protein acetylationGO:000647320.020
negative regulation of cell cycle phase transitionGO:190198850.020
negative regulation of cell cycleGO:0045786140.020
protein polyubiquitinationGO:000020940.020
microtubule based processGO:0007017600.019
covalent chromatin modificationGO:0016569200.019
cell part morphogenesisGO:00329902460.019
cellular macromolecular complex assemblyGO:0034622240.019
cellular response to chemical stimulusGO:00708871570.019
spindle assemblyGO:005122520.019
positive regulation of cellular component biogenesisGO:004408930.019
spindle assembly involved in mitosisGO:009030710.019
negative regulation of cell cycle g2 m phase transitionGO:190275010.019
cellular component assembly involved in morphogenesisGO:00109271070.019
digestive system developmentGO:00551232890.019
male meiosisGO:000714020.018
regulation of intracellular protein transportGO:003315730.018
positive regulation of transportGO:005105020.018
gtp metabolic processGO:004603940.018
phosphorus metabolic processGO:00067931090.018
peptidyl threonine phosphorylationGO:001810710.018
meiotic nuclear divisionGO:000712640.018
dna recombinationGO:000631050.018
mitotic metaphase plate congressionGO:000708010.017
oxoacid metabolic processGO:0043436310.017
regulation of cysteine type endopeptidase activityGO:2000116210.017
striated muscle cell differentiationGO:00511461290.017
stem cell differentiationGO:00488631170.017
production of molecular mediator of immune responseGO:000244020.017
locomotionGO:00400113130.017
Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
positive regulation of leukocyte mediated immunityGO:000270510.016
muscle cell developmentGO:00550011150.016
regulation of dna templated transcription in response to stressGO:004362000.016
negative regulation of catabolic processGO:000989530.016
regulation of organelle assemblyGO:190211540.016
oocyte developmentGO:0048599140.016
regulation of chromosome organizationGO:003304450.016
organonitrogen compound metabolic processGO:1901564740.016
mitotic g2 dna damage checkpointGO:000709530.015
vasculature developmentGO:00019442780.015
reproductive processGO:0022414400.015
Worm
negative regulation of rna metabolic processGO:0051253480.015
regulation of chromatin organizationGO:190227550.015
guanosine containing compound metabolic processGO:190106840.015
macromolecule methylationGO:0043414190.015
response to mechanical stimulusGO:0009612240.015
recombinational repairGO:000072510.015
catabolic processGO:0009056320.015
mitotic recombinationGO:000631220.015
positive regulation of cellular biosynthetic processGO:0031328680.015
ribonucleoside biosynthetic processGO:004245520.015
protein localization to nucleusGO:003450430.015
b cell mediated immunityGO:001972430.015
cell deathGO:00082191210.015
organelle fissionGO:0048285230.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
regulation of developmental processGO:00507932470.015
response to radiationGO:0009314510.015
cellular response to dna damage stimulusGO:0006974240.015
tissue remodelingGO:004877140.015
germ cell developmentGO:0007281220.014
positive regulation of cell divisionGO:005178120.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
regulation of cell shapeGO:000836010.014
regulation of bindingGO:005109830.014
muscle structure developmentGO:00610611960.014
cell motilityGO:00488702440.014
regulation of cell proliferationGO:0042127370.014
histone h3 k4 methylationGO:005156820.014
positive regulation of transcription dna templatedGO:0045893570.013
regulation of protein transportGO:005122330.013
apoptotic signaling pathwayGO:0097190230.013
reciprocal dna recombinationGO:003582510.013
positive regulation of cell activationGO:005086710.013
specification of symmetryGO:00097992040.013
mitotic cell cycle phase transitionGO:004477290.013
phagocytosisGO:000690930.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
positive regulation of cellular amine metabolic processGO:003324000.013
cell surface receptor signaling pathwayGO:00071663250.013
small molecule metabolic processGO:0044281770.013
antimicrobial humoral responseGO:001973020.012
cellular protein complex assemblyGO:0043623190.012
positive regulation of cellular protein metabolic processGO:0032270220.012
developmental cell growthGO:0048588520.012
negative regulation of protein transportGO:005122430.012
immunoglobulin productionGO:000237710.012
internal protein amino acid acetylationGO:000647520.012
regulation of mitotic cell cycle phase transitionGO:190199080.012
adult behaviorGO:003053420.012
rna localizationGO:000640340.012
regulation of purine nucleotide catabolic processGO:003312120.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.012
response to endogenous stimulusGO:0009719830.012
regulation of protein metabolic processGO:0051246560.011
response to drugGO:004249330.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.011
female meiotic divisionGO:000714320.011
chromosome organizationGO:0051276310.011
negative regulation of intracellular transportGO:003238730.011
cell cycle checkpointGO:000007570.011
cell migrationGO:00164772370.011
response to external biotic stimulusGO:0043207970.011
regulation of multicellular organism growthGO:004001440.011
positive regulation of programmed cell deathGO:0043068290.011
positive regulation of proteolysisGO:0045862100.011
developmental growth involved in morphogenesisGO:0060560860.011
negative regulation of cell divisionGO:005178240.011
cellular component movementGO:00069283350.011
protein import into nucleusGO:000660630.011
positive regulation of dna metabolic processGO:005105410.011
somatic cell dna recombinationGO:001644410.011
cell proliferationGO:0008283800.011
Fly
positive regulation of macromolecule biosynthetic processGO:0010557590.010
zymogen activationGO:003163830.010
regulation of protein modification processGO:0031399290.010
cytoskeleton dependent cytokinesisGO:006164030.010
organic substance catabolic processGO:1901575280.010
primary neural tube formationGO:001402010.010
protein modification by small protein conjugation or removalGO:0070647140.010
gtp catabolic processGO:000618420.010
regulation of response to stressGO:0080134360.010
mitotic nuclear divisionGO:0007067180.010
negative regulation of response to stimulusGO:00485851040.010
regulation of neural precursor cell proliferationGO:200017730.010
regulation of catalytic activityGO:0050790550.010
cell cycle phase transitionGO:004477090.010

orc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.067
disease of cellular proliferationDOID:1456600.067
disease of anatomical entityDOID:700.067
organ system cancerDOID:005068600.055
nervous system diseaseDOID:86300.029
thoracic cancerDOID:509300.029
colorectal cancerDOID:925600.025
intestinal cancerDOID:1015500.025
gastrointestinal system cancerDOID:311900.025
large intestine cancerDOID:567200.025
disease of metabolismDOID:001466700.011