Danio rerio

0 known processes

appbp2

amyloid beta precursor protein (cytoplasmic tail) binding protein 2

(Aliases: wu:fc25c09,wu:fb78e11,zgc:76971)

appbp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.154
agingGO:000756820.072
nitrogen compound metabolic processGO:00068073190.056
cellular nitrogen compound metabolic processGO:00346412900.050
maintenance of locationGO:005123540.046
nucleobase containing compound metabolic processGO:00061392740.044
heterocycle metabolic processGO:00464832900.043
phagocytosisGO:000690930.041
nuclear transportGO:005116940.039
establishment of protein localization to organelleGO:007259440.039
cellular macromolecule metabolic processGO:00442603910.039
organic cyclic compound metabolic processGO:19013603010.038
meiotic nuclear divisionGO:000712640.038
positive regulation of transportGO:005105020.036
cellular aromatic compound metabolic processGO:00067252950.036
multicellular organism growthGO:003526440.036
nucleocytoplasmic transportGO:000691340.035
proteolysis involved in cellular protein catabolic processGO:005160330.034
gtp metabolic processGO:004603940.034
gene expressionGO:00104672520.034
stem cell maintenanceGO:001982740.033
ubiquitin dependent protein catabolic processGO:000651130.033
signal transductionGO:00071654550.033
modification dependent macromolecule catabolic processGO:004363230.032
mitochondrion organizationGO:000700540.032
establishment of localizationGO:00512342440.032
transportGO:00068102200.031
positive regulation of catabolic processGO:000989640.031
organic substance biosynthetic processGO:19015762890.031
protein localization to nucleusGO:003450430.031
guanosine containing compound metabolic processGO:190106840.030
nucleic acid metabolic processGO:00903042440.030
rna metabolic processGO:00160702190.030
regulation of establishment of protein localizationGO:007020140.030
response to drugGO:004249330.030
positive regulation of cellular component biogenesisGO:004408930.030
cellular response to external stimulusGO:007149620.030
gtp catabolic processGO:000618420.030
cellular protein catabolic processGO:004425740.030
response to chemicalGO:00422213200.029
biosynthetic processGO:00090582940.029
regulation of macromolecule metabolic processGO:00602553170.029
regulation of multicellular organism growthGO:004001440.029
regulation of protein transportGO:005122330.029
lipid storageGO:001991510.029
positive regulation of cellular catabolic processGO:003133130.029
regulation of metabolic processGO:00192223590.028
modification dependent protein catabolic processGO:001994130.028
protein importGO:001703830.028
proteasomal protein catabolic processGO:001049820.028
amine metabolic processGO:000930820.027
locomotionGO:00400113130.027
negative regulation of biological processGO:00485193040.027
locomotor rhythmGO:004547530.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
response to stressGO:00069502630.027
guanosine containing compound catabolic processGO:190106920.026
single organism nuclear importGO:190259330.026
regulation of primary metabolic processGO:00800903110.026
cellular amine metabolic processGO:004410620.026
regulation of protein complex assemblyGO:004325430.026
regulation of response to stimulusGO:00485832690.026
regulation of mrna splicing via spliceosomeGO:004802430.025
central nervous system developmentGO:00074173870.025
transcription dna templatedGO:00063511810.025
cell surface receptor signaling pathwayGO:00071663250.025
regulation of cellular biosynthetic processGO:00313262450.025
ribonucleoside monophosphate catabolic processGO:000915840.025
regulation of cytokine productionGO:000181730.025
single organism localizationGO:19025782250.025
heterocycle biosynthetic processGO:00181302150.025
cellular component movementGO:00069283350.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
nuclear importGO:005117030.025
regulation of mrna processingGO:005068430.025
single organism metabolic processGO:00447102170.025
cellular biosynthetic processGO:00442492860.024
single organism transportGO:00447652060.024
transmembrane transportGO:00550851200.024
regulation of nitrogen compound metabolic processGO:00511712510.024
neuron differentiationGO:00301823530.024
regulation of cytoplasmic transportGO:190364940.024
protein targeting to nucleusGO:004474430.024
organelle fusionGO:004828430.024
regulation of biological qualityGO:00650082630.024
cellular macromolecule biosynthetic processGO:00346452240.024
regulation of cellular metabolic processGO:00313233200.024
cellular component biogenesisGO:00440851780.024
cytokinesisGO:000091030.024
regionalizationGO:00030022740.024
cellular component disassemblyGO:002241110.023
regulation of signalingGO:00230512350.023
positive regulation of cell cycleGO:004578730.023
regulation of protein import into nucleusGO:004230620.023
membrane fusionGO:006102520.023
cellular response to extracellular stimulusGO:003166820.023
embryonic organ morphogenesisGO:00485622740.023
regulation of signal transductionGO:00099662250.023
endosomal transportGO:001619720.023
cell motilityGO:00488702440.023
cell morphogenesisGO:00009022890.023
regulation of protein catabolic processGO:004217610.023
cellular response to topologically incorrect proteinGO:003596720.023
embryo development ending in birth or egg hatchingGO:00097922710.023
response to topologically incorrect proteinGO:003596620.023
macromolecule biosynthetic processGO:00090592270.023
cellular component morphogenesisGO:00329893360.023
regulation of gene expressionGO:00104682650.022
negative regulation of cellular processGO:00485232830.022
cellular response to starvationGO:000926710.022
rna localizationGO:000640340.022
single organism membrane fusionGO:004480120.022
regulation of meiotic cell cycleGO:005144510.022
phagocytosis engulfmentGO:000691110.022
cell projection morphogenesisGO:00488582440.022
nucleoside monophosphate catabolic processGO:000912540.022
regulation of nucleoside metabolic processGO:000911820.022
embryonic organ developmentGO:00485683810.022
cellular ketone metabolic processGO:0042180110.022
organonitrogen compound metabolic processGO:1901564740.022
regulation of nucleocytoplasmic transportGO:004682220.022
cellular component assemblyGO:00226071700.022
regulation of protein targetingGO:190353320.022
protein import into nucleusGO:000660630.022
regulation of biosynthetic processGO:00098892500.022
tube morphogenesisGO:00352393490.022
regulation of cell communicationGO:00106462320.021
regulation of nucleotide catabolic processGO:003081120.021
cellular response to nutrient levelsGO:003166920.021
small molecule metabolic processGO:0044281770.021
organic cyclic compound biosynthetic processGO:19013622230.021
regulation of cell shapeGO:000836010.021
regulation of protein localization to nucleusGO:190018020.021
cognitionGO:005089010.021
regulation of cellular amino acid metabolic processGO:000652100.021
atp catabolic processGO:000620040.021
brain developmentGO:00074202930.021
centrosome organizationGO:005129710.021
regulation of rna metabolic processGO:00512522240.021
chemosensory behaviorGO:000763510.021
regulation of organelle assemblyGO:190211540.021
protein localization to plasma membraneGO:007265910.020
cell projection organizationGO:00300302840.020
negative regulation of protein phosphorylationGO:000193340.020
specification of symmetryGO:00097992040.020
regulation of circadian rhythmGO:004275240.020
alternative mrna splicing via spliceosomeGO:000038010.020
response to external stimulusGO:00096052640.020
regulation of bindingGO:005109830.020
regulation of protein ubiquitinationGO:003139630.020
membrane invaginationGO:001032410.020
aromatic compound biosynthetic processGO:00194382170.020
meiotic cell cycle processGO:190304630.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cell migrationGO:00164772370.020
response to uvGO:000941130.020
cellular amide metabolic processGO:004360340.020
cellular amino acid metabolic processGO:000652070.020
regulation of cellular amine metabolic processGO:003323800.020
purine nucleoside monophosphate catabolic processGO:000912840.020
protein polymerizationGO:005125840.020
meiotic chromosome segregationGO:004513230.020
regulation of synapse organizationGO:005080730.020
cell part morphogenesisGO:00329902460.020
heart developmentGO:00075073130.020
actin polymerization or depolymerizationGO:000815420.020
mitotic dna integrity checkpointGO:004477440.020
organelle organizationGO:00069962270.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
regulation of cellular ketone metabolic processGO:001056570.020
development of primary female sexual characteristicsGO:004654540.019
protein metabolic processGO:00195381830.019
regulation of intracellular protein transportGO:003315730.019
generation of neuronsGO:00486993850.019
rna biosynthetic processGO:00327741810.019
carboxylic acid metabolic processGO:0019752220.019
nucleic acid templated transcriptionGO:00976591810.019
spermatid developmentGO:000728620.019
nucleobase containing compound biosynthetic processGO:00346542050.019
regulation of cell activationGO:005086510.019
regulation of macromolecule biosynthetic processGO:00105562250.019
adult behaviorGO:003053420.019
protein secretionGO:000930610.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
regulation of synapse assemblyGO:005196330.019
positive regulation of secretion by cellGO:190353210.019
head developmentGO:00603223030.019
morphogenesis of an epitheliumGO:00020093330.019
regulation of purine nucleotide catabolic processGO:003312120.018
autophagyGO:000691440.018
organic acid metabolic processGO:0006082310.018
sensory organ developmentGO:00074233930.018
macromolecular complex disassemblyGO:003298410.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
golgi vesicle transportGO:004819330.018
determination of bilateral symmetryGO:00098552040.018
synaptic growth at neuromuscular junctionGO:005112420.018
regulation of developmental processGO:00507932470.018
positive regulation of secretionGO:005104710.018
system processGO:00030081850.018
regulation of rna biosynthetic processGO:20011412130.018
digestive system developmentGO:00551232890.017
i kappab kinase nf kappab signalingGO:000724940.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
regulation of reproductive processGO:200024140.017
female sex differentiationGO:004666040.017
regulation of synaptic plasticityGO:004816710.017
protein complex disassemblyGO:004324110.017
regulation of transcription dna templatedGO:00063552130.017
stem cell proliferationGO:007208940.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
er nucleus signaling pathwayGO:000698420.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of gtp catabolic processGO:003312420.017
g1 s transition of mitotic cell cycleGO:000008210.017
cellular respirationGO:004533330.017
centrosome cycleGO:000709810.017
cytoskeleton dependent cytokinesisGO:006164030.017
oxoacid metabolic processGO:0043436310.017
response to organic substanceGO:00100331530.016
multi organism processGO:00517041340.016
positive regulation of biological processGO:00485182530.016
extrinsic apoptotic signaling pathwayGO:009719130.016
determination of left right symmetryGO:00073681790.016
positive regulation of nucleoside metabolic processGO:004597910.016
positive regulation of cytokine productionGO:000181920.016
exocytosisGO:000688710.016
internal protein amino acid acetylationGO:000647520.016
actin filament polymerizationGO:003004120.016
ion transmembrane transportGO:0034220910.016
regulation of gtpase activityGO:004308720.016
neuron developmentGO:00486662620.016
immune system processGO:00023762410.016
organelle assemblyGO:00709251100.016
cell cycle g1 s phase transitionGO:004484310.016
regulation of neural precursor cell proliferationGO:200017730.016
eye developmentGO:00016542770.016
cellular localizationGO:0051641970.016
negative regulation of kinase activityGO:003367340.016
localization of cellGO:00516742440.016
cellular response to chemical stimulusGO:00708871570.016
spermatid differentiationGO:004851520.016
protein acetylationGO:000647320.016
cell substrate adhesionGO:003158940.016
cell matrix adhesionGO:000716040.016
internal peptidyl lysine acetylationGO:001839320.015
peptidyl lysine acetylationGO:001839420.015
positive regulation of gtp catabolic processGO:003312610.015
positive regulation of cell activationGO:005086710.015
fertilizationGO:000956630.015
response to unfolded proteinGO:000698620.015
macroautophagyGO:001623610.015
production of molecular mediator of immune responseGO:000244020.015
developmental programmed cell deathGO:001062340.015
nucleic acid transportGO:005065720.015
apoptotic processGO:00069151160.015
peptidyl serine phosphorylationGO:001810510.015
positive regulation of map kinase activityGO:004340630.015
digestive tract developmentGO:00485652650.015
negative regulation of synapse assemblyGO:005196420.015
ameboidal type cell migrationGO:00016671430.015
nuclear exportGO:005116810.015
positive regulation of cell adhesionGO:004578510.015
oocyte anterior posterior axis specificationGO:000731440.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
regulation of stem cell proliferationGO:007209120.015
protein acylationGO:004354330.015
positive regulation of inflammatory responseGO:005072910.015
rna transportGO:005065820.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
erk1 and erk2 cascadeGO:007037140.015
negative regulation of cytoplasmic transportGO:190365020.015
vasculature developmentGO:00019442780.015
dorsal ventral pattern formationGO:00099531250.014
protein dephosphorylationGO:000647030.014
positive regulation of cytoskeleton organizationGO:005149530.014
cellular response to biotic stimulusGO:007121630.014
secondary metabolic processGO:001974830.014
negative regulation of protein kinase activityGO:000646940.014
cellular carbohydrate metabolic processGO:004426240.014
cellular protein metabolic processGO:00442671290.014
peptide transportGO:001583310.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
stem cell divisionGO:001714510.014
positive regulation of gtpase activityGO:004354710.014
negative regulation of catabolic processGO:000989530.014
peptidyl serine modificationGO:001820920.014
chordate embryonic developmentGO:00430092710.014
regulation of multicellular organismal processGO:00512392770.014
positive regulation of translationGO:004572710.014
gland developmentGO:00487321430.014
cellular response to lipopolysaccharideGO:007122230.014
cellular response to unfolded proteinGO:003462020.014
tissue remodelingGO:004877140.014
growthGO:00400071740.014
camera type eye developmentGO:00430102220.014
regulation of cell substrate adhesionGO:001081010.014
endoplasmic reticulum unfolded protein responseGO:003096820.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
somatic stem cell maintenanceGO:003501910.014
regulation of protein polymerizationGO:003227120.014
regulation of autophagyGO:001050630.014
g2 dna damage checkpointGO:003157230.014
regulation of erk1 and erk2 cascadeGO:007037240.013
single organism organelle organizationGO:19025891990.013
synaptic vesicle localizationGO:009747910.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
establishment of synaptic vesicle localizationGO:009748010.013
negative regulation of cytokine productionGO:000181810.013
neurotransmitter transportGO:000683620.013
lamellipodium assemblyGO:003003210.013
blood vessel developmentGO:00015682460.013
blood vessel morphogenesisGO:00485142160.013
compound eye developmentGO:004874920.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
sequestering of metal ionGO:005123830.013
axonogenesisGO:00074091520.013
positive regulation of nucleotide catabolic processGO:003081310.013
synaptic vesicle transportGO:004848910.013
lateral inhibitionGO:004633110.013
establishment of rna localizationGO:005123630.013
leukocyte proliferationGO:007066110.013
mitotic dna damage checkpointGO:004477340.013
negative regulation of protein transportGO:005122430.013
actin filament based movementGO:003004810.013
hormone secretionGO:004687920.013
cellular response to radiationGO:007147840.013
cell deathGO:00082191210.013
response to hydrogen peroxideGO:004254230.013
protein homooligomerizationGO:005126030.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
positive regulation of notch signaling pathwayGO:004574730.013
neuroblast proliferationGO:000740520.013
response to abiotic stimulusGO:00096281220.013
female gonad developmentGO:000858540.013
regulation of cell projection assemblyGO:006049140.013
nucleobase containing compound transportGO:001593120.013
positive regulation of cellular processGO:00485222010.013
protein stabilizationGO:005082120.013
negative regulation of defense responseGO:003134820.013
cellular response to organic substanceGO:00713101050.013
axon developmentGO:00615641660.013
signal transduction in absence of ligandGO:003803410.013
single fertilizationGO:000733830.013
regulation of multicellular organismal developmentGO:20000262230.013
muscle structure developmentGO:00610611960.013
translational initiationGO:000641330.012
microtubule organizing center organizationGO:003102310.012
female meiotic divisionGO:000714320.012
negative regulation of map kinase activityGO:004340720.012
positive regulation of immune effector processGO:000269930.012
gastrulationGO:00073692080.012
primary neural tube formationGO:001402010.012
regulation of protein complex disassemblyGO:004324410.012
regulation of stem cell differentiationGO:200073640.012
lamellipodium organizationGO:009758110.012
neuromuscular synaptic transmissionGO:000727420.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
b cell activationGO:004211320.012
mononuclear cell proliferationGO:003294310.012
neuron projection morphogenesisGO:00488121610.012
pole plasm assemblyGO:000731540.012
regulation of rho protein signal transductionGO:003502320.012
programmed cell deathGO:00125011190.012
negative regulation of protein localization to nucleusGO:190018120.012
positive regulation of ras protein signal transductionGO:004657910.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
intracellular signal transductionGO:0035556850.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
interspecies interaction between organismsGO:004441940.012
immune system developmentGO:00025201910.012
regulation of anatomical structure morphogenesisGO:00226031300.012
neuron projection developmentGO:00311751800.012
somatic muscle developmentGO:000752540.012
establishment of protein localization to plasma membraneGO:009000210.012
neurotransmitter secretionGO:000726920.012
apoptotic process involved in developmentGO:190274220.012
activation of mapk activityGO:000018730.012
regulation of carbohydrate metabolic processGO:000610940.012
retina development in camera type eyeGO:00600411460.012
epithelial tube morphogenesisGO:00605621480.012
establishment of localization in cellGO:0051649770.012
negative regulation of metabolic processGO:0009892860.012
tube closureGO:006060610.012
anterior posterior pattern specificationGO:00099521520.012
determination of heart left right asymmetryGO:00613711170.012
cytosolic calcium ion transportGO:006040130.012
ion transportGO:00068111140.012
lymphocyte proliferationGO:004665110.012
response to monosaccharideGO:003428430.012
vacuolar transportGO:000703420.012
carbohydrate homeostasisGO:003350010.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
protein polyubiquitinationGO:000020940.012
mitochondrial transportGO:000683920.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
negative regulation of mapk cascadeGO:004340940.012
germ line stem cell maintenanceGO:003071820.012
spindle assemblyGO:005122520.012
phosphorus metabolic processGO:00067931090.012
hepaticobiliary system developmentGO:0061008980.012
cell substrate junction assemblyGO:000704420.011
response to alkaloidGO:004327920.011
negative regulation of nuclear divisionGO:005178430.011
regulation of cellular protein catabolic processGO:190336210.011
negative regulation of intracellular transportGO:003238730.011
viral processGO:001603210.011
regulation of metal ion transportGO:001095940.011
angiogenesisGO:00015251580.011
cellular response to molecule of bacterial originGO:007121930.011
negative regulation of macromolecule metabolic processGO:0010605760.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
digestive tract morphogenesisGO:00485462310.011
homeostatic processGO:00425921420.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of jak stat cascadeGO:004642530.011
neuron neuron synaptic transmissionGO:000727010.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
neuron remodelingGO:001632210.011
cilium morphogenesisGO:0060271850.011
negative regulation of intracellular protein transportGO:009031730.011
transcription from rna polymerase ii promoterGO:0006366800.011
dna templated transcription elongationGO:000635430.011
mitotic cytokinesisGO:000028130.011
startle responseGO:000196440.011
developmental growthGO:00485891660.011
deathGO:00162651210.011
cytoplasm organizationGO:000702840.011
antimicrobial humoral responseGO:001973020.011
regulation of inflammatory responseGO:005072720.011
liver developmentGO:0001889960.011
lipid catabolic processGO:001604240.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
sensory organ morphogenesisGO:00905962000.011
positive regulation of protein polymerizationGO:003227320.011
regulation of response to biotic stimulusGO:000283120.011
toll like receptor signaling pathwayGO:000222440.011
neurological system processGO:0050877620.011
regulation of cellular component organizationGO:0051128860.011
er to golgi vesicle mediated transportGO:000688810.011
protein targeting to membraneGO:000661210.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
hemopoiesisGO:00300971830.011
peptide metabolic processGO:000651810.011
negative regulation of protein complex assemblyGO:003133310.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
response to nutrientGO:000758430.011
transmission of nerve impulseGO:0019226190.011
regulation of dna templated transcription elongationGO:003278430.011
meiosis iGO:000712710.011
regulation of muscle contractionGO:000693730.011
negative regulation of translationGO:001714810.011
response to endogenous stimulusGO:0009719830.011
multi organism cellular processGO:004476420.011
alcohol biosynthetic processGO:004616520.010
negative regulation of multi organism processGO:004390130.010
regulation of sequestering of calcium ionGO:005128240.010
positive regulation of stress activated mapk cascadeGO:003287430.010
sequestering of calcium ionGO:005120830.010
regulation of organ growthGO:004662030.010
macromolecule modificationGO:00434121110.010
carbohydrate biosynthetic processGO:001605110.010
cation transmembrane transportGO:0098655650.010
positive regulation of dna metabolic processGO:005105410.010
mitotic cell cycle embryonicGO:004544820.010
positive regulation of multi organism processGO:004390230.010
response to woundingGO:00096111160.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
regulation of production of molecular mediator of immune responseGO:000270010.010
cellular component assembly involved in morphogenesisGO:00109271070.010
regulation of protein bindingGO:004339330.010
cell cycle g2 m phase transitionGO:004483940.010
small molecule catabolic processGO:004428230.010
response to carbohydrateGO:000974330.010
double strand break repairGO:000630230.010
positive regulation of leukocyte differentiationGO:190210710.010

appbp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.024
musculoskeletal system diseaseDOID:1700.018
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
cardiovascular system diseaseDOID:128700.014
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012
sensory system diseaseDOID:005015500.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
connective tissue diseaseDOID:6500.010