Danio rerio

19 known processes

bik

BCL2-interacting killer (apoptosis-inducing)

(Aliases: si:dkey-31f5.6)

bik biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.213
response to chemicalGO:00422213200.168
regulation of muscle contractionGO:000693730.156
response to organic substanceGO:00100331530.151
single organism transportGO:00447652060.119
head developmentGO:00603223030.100
regulation of nitrogen compound metabolic processGO:00511712510.092
regulation of primary metabolic processGO:00800903110.089
g protein coupled receptor signaling pathwayGO:0007186740.080
single organism membrane fusionGO:004480120.079
single organism metabolic processGO:00447102170.078
brain developmentGO:00074202930.076
nitrogen compound metabolic processGO:00068073190.071
heterocycle metabolic processGO:00464832900.067
guanosine containing compound catabolic processGO:190106920.066
gtp metabolic processGO:004603940.064
regulation of response to stimulusGO:00485832690.063
signal transduction in absence of ligandGO:003803410.063
negative regulation of mitosisGO:004583930.063
central nervous system developmentGO:00074173870.062
organic cyclic compound metabolic processGO:19013603010.061
guanosine containing compound metabolic processGO:190106840.060
homeostatic processGO:00425921420.059
larval developmentGO:000216420.059
cellular response to chemical stimulusGO:00708871570.058
immune system processGO:00023762410.058
chordate embryonic developmentGO:00430092710.058
cellular response to endogenous stimulusGO:0071495680.057
cellular response to organic substanceGO:00713101050.056
transportGO:00068102200.056
regulation of metal ion transportGO:001095940.055
cellular nitrogen compound biosynthetic processGO:00442712180.055
response to stressGO:00069502630.055
regulation of signalingGO:00230512350.054
positive regulation of nitrogen compound metabolic processGO:0051173690.054
organic cyclic compound biosynthetic processGO:19013622230.053
regulation of system processGO:0044057400.053
response to lipidGO:0033993600.053
gtp catabolic processGO:000618420.053
regulation of tyrosine phosphorylation of stat proteinGO:004250910.052
nucleobase containing compound metabolic processGO:00061392740.052
cellular aromatic compound metabolic processGO:00067252950.051
programmed cell deathGO:00125011190.051
neurological system processGO:0050877620.049
regulation of protein localization to nucleusGO:190018020.047
cellular macromolecule metabolic processGO:00442603910.047
negative regulation of nuclear divisionGO:005178430.047
immune system developmentGO:00025201910.046
regulation of rna metabolic processGO:00512522240.045
regulation of sodium ion transportGO:000202820.045
response to endogenous stimulusGO:0009719830.044
muscle structure developmentGO:00610611960.044
cellular nitrogen compound metabolic processGO:00346412900.044
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.044
regulation of signal transductionGO:00099662250.044
cell surface receptor signaling pathwayGO:00071663250.043
transmembrane transportGO:00550851200.043
response to transition metal nanoparticleGO:1990267280.042
positive regulation of purine nucleotide catabolic processGO:003312310.042
sensory organ developmentGO:00074233930.042
heterocycle biosynthetic processGO:00181302150.041
regulation of biological qualityGO:00650082630.041
small molecule metabolic processGO:0044281770.041
regulation of cellular metabolic processGO:00313233200.041
positive regulation of cellular catabolic processGO:003133130.040
gene expressionGO:00104672520.039
regulation of nucleobase containing compound metabolic processGO:00192192500.039
mitochondrion organizationGO:000700540.039
positive regulation of gtp catabolic processGO:003312610.039
multicellular organismal homeostasisGO:0048871290.038
regulation of multicellular organismal processGO:00512392770.038
multicellular organism growthGO:003526440.038
regulation of gene expressionGO:00104682650.037
response to glucocorticoidGO:005138410.037
regulation of establishment of protein localizationGO:007020140.036
establishment of localizationGO:00512342440.036
regulation of synaptic plasticityGO:004816710.036
negative regulation of cellular processGO:00485232830.036
regulation of metabolic processGO:00192223590.036
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.035
regulation of ion transportGO:0043269220.035
rna biosynthetic processGO:00327741810.035
agingGO:000756820.035
regulation of developmental processGO:00507932470.035
regulation of biosynthetic processGO:00098892500.034
positive regulation of neuron apoptotic processGO:004352510.033
protein import into nucleusGO:000660630.033
regulation of gtp catabolic processGO:003312420.033
system processGO:00030081850.032
nucleic acid metabolic processGO:00903042440.032
regulation of nucleoside metabolic processGO:000911820.032
regulation of tube sizeGO:003515020.031
response to drugGO:004249330.031
membrane fusionGO:006102520.030
positive regulation of cell cycleGO:004578730.030
protein localization to nucleusGO:003450430.030
organonitrogen compound metabolic processGO:1901564740.030
regulation of cellular biosynthetic processGO:00313262450.030
regulation of protein transportGO:005122330.030
extrinsic apoptotic signaling pathwayGO:009719130.029
regulation of gtpase activityGO:004308720.029
mononuclear cell proliferationGO:003294310.029
positive regulation of blood circulationGO:190352420.029
embryo development ending in birth or egg hatchingGO:00097922710.028
negative regulation of biological processGO:00485193040.028
establishment of protein localization to organelleGO:007259440.028
regulation of purine nucleotide catabolic processGO:003312120.028
positive regulation of catabolic processGO:000989640.028
apoptotic processGO:00069151160.027
action potentialGO:0001508190.027
negative regulation of metabolic processGO:0009892860.027
organic acid metabolic processGO:0006082310.027
regulation of cytokine productionGO:000181730.027
circulatory system processGO:0003013870.027
positive regulation of macromolecule metabolic processGO:0010604930.027
regulation of cytoplasmic transportGO:190364940.027
cell motilityGO:00488702440.027
response to organic cyclic compoundGO:0014070510.026
positive regulation of gtpase activityGO:004354710.026
metal ion transportGO:0030001580.026
response to cadmium ionGO:0046686140.026
positive regulation of biological processGO:00485182530.026
deathGO:00162651210.026
aromatic compound biosynthetic processGO:00194382170.026
nucleic acid templated transcriptionGO:00976591810.025
cellular component morphogenesisGO:00329893360.025
biosynthetic processGO:00090582940.025
regulation of macromolecule metabolic processGO:00602553170.025
regulation of circadian sleep wake cycle sleepGO:004518710.025
positive regulation of epithelial cell differentiationGO:003085820.025
growthGO:00400071740.025
striated muscle tissue developmentGO:00147061100.024
embryonic hemopoiesisGO:0035162530.024
establishment of endothelial barrierGO:006102830.024
positive regulation of neuron deathGO:190121610.024
maintenance of locationGO:005123540.024
regulation of inflammatory responseGO:005072720.024
positive regulation of apoptotic signaling pathwayGO:200123510.024
regulation of blood pressureGO:000821710.024
determination of bilateral symmetryGO:00098552040.024
negative regulation of signalingGO:0023057960.023
nuclear transportGO:005116940.023
muscle cell differentiationGO:00426921390.023
response to hormoneGO:0009725480.023
response to external stimulusGO:00096052640.023
regulation of blood vessel sizeGO:005088020.022
regulation of endothelial cell proliferationGO:000193610.022
tube morphogenesisGO:00352393490.022
morphogenesis of an epitheliumGO:00020093330.022
phagocytosisGO:000690930.022
organelle fusionGO:004828430.022
response to corticosteroidGO:003196010.022
negative regulation of gene expressionGO:0010629650.022
nucleobase containing compound biosynthetic processGO:00346542050.022
cellular macromolecule biosynthetic processGO:00346452240.022
dorsal ventral pattern formationGO:00099531250.022
regulation of response to oxidative stressGO:190288220.021
macromolecule biosynthetic processGO:00090592270.021
transmission of nerve impulseGO:0019226190.021
single organism localizationGO:19025782250.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
rna metabolic processGO:00160702190.021
positive regulation of transportGO:005105020.021
sensory perception of painGO:001923310.021
regulation of circadian rhythmGO:004275240.021
heart developmentGO:00075073130.020
single organism nuclear importGO:190259330.020
erythrocyte differentiationGO:0030218540.020
neuron neuron synaptic transmissionGO:000727010.020
regulation of cell communicationGO:00106462320.020
generation of neuronsGO:00486993850.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.019
regulation of reactive oxygen species metabolic processGO:200037720.019
regulation of membrane potentialGO:0042391230.019
negative regulation of macromolecule metabolic processGO:0010605760.019
organic substance biosynthetic processGO:19015762890.019
amine metabolic processGO:000930820.019
cellular component biogenesisGO:00440851780.019
mesenchyme developmentGO:00604851270.019
smooth muscle contractionGO:000693920.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.019
regulation of heart contractionGO:0008016320.019
positive regulation of cellular component biogenesisGO:004408930.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
regulation of cardiac muscle contractionGO:005511720.019
regulation of intracellular protein transportGO:003315730.019
positive regulation of signal transductionGO:0009967560.019
anatomical structure homeostasisGO:0060249360.019
cellular response to oxygen levelsGO:007145310.019
positive regulation of cellular processGO:00485222010.018
regulation of mitochondrion organizationGO:001082110.018
positive regulation of nucleotide catabolic processGO:003081310.018
cell cycle arrestGO:000705010.018
embryonic organ morphogenesisGO:00485622740.018
phosphate containing compound metabolic processGO:00067961080.018
positive regulation of muscle cell differentiationGO:005114910.018
ion transmembrane transportGO:0034220910.018
response to nutrientGO:000758430.018
regulation of striated muscle contractionGO:000694220.018
ventricular cardiac muscle tissue developmentGO:000322930.018
oxoacid metabolic processGO:0043436310.018
regulation of multicellular organism growthGO:004001440.017
mesenchymal cell differentiationGO:0048762870.017
regulation of jak stat cascadeGO:004642530.017
embryonic organ developmentGO:00485683810.017
regulation of reproductive processGO:200024140.017
sleepGO:003043110.017
single organism biosynthetic processGO:0044711710.017
regulation of cellular amine metabolic processGO:003323800.017
nuclear importGO:005117030.017
superoxide metabolic processGO:000680120.017
regulation of cellular component organizationGO:0051128860.017
protein importGO:001703830.017
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.017
liver developmentGO:0001889960.017
positive regulation of nucleoside metabolic processGO:004597910.016
lipid metabolic processGO:0006629520.016
positive regulation of cytokine productionGO:000181920.016
peptide transportGO:001583310.016
protein acetylationGO:000647320.016
somite developmentGO:0061053960.016
positive regulation of response to stimulusGO:0048584800.016
tyrosine phosphorylation of stat proteinGO:000726010.016
tissue homeostasisGO:0001894250.016
pigmentationGO:0043473850.016
cellular amine metabolic processGO:004410620.016
regulation of macromolecule biosynthetic processGO:00105562250.016
cellular response to hypoxiaGO:007145610.016
response to methylmercuryGO:0051597110.016
negative regulation of kinase activityGO:003367340.016
cognitionGO:005089010.016
myeloid cell homeostasisGO:0002262560.016
cell proliferationGO:0008283800.016
regulation of rna biosynthetic processGO:20011412130.016
negative regulation of cellular metabolic processGO:0031324770.016
regulation of epithelial cell proliferationGO:005067830.016
cellular amino acid metabolic processGO:000652070.016
cellular response to hormone stimulusGO:0032870390.016
reactive nitrogen species metabolic processGO:200105700.016
cell migrationGO:00164772370.016
locomotionGO:00400113130.015
cellular response to decreased oxygen levelsGO:003629410.015
digestive tract developmentGO:00485652650.015
regulation of cellular amino acid metabolic processGO:000652100.015
renal system developmentGO:0072001940.015
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.015
stem cell maintenanceGO:001982740.015
circadian sleep wake cycle sleepGO:005080210.015
digestive system developmentGO:00551232890.015
regulation of calcium ion transportGO:005192420.015
embryonic skeletal system morphogenesisGO:0048704930.015
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.015
carbohydrate derivative metabolic processGO:1901135610.015
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.015
regulation of autophagyGO:001050630.015
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.015
bmp signaling pathwayGO:0030509520.015
cellular ketone metabolic processGO:0042180110.015
nucleocytoplasmic transportGO:000691340.015
cellular response to radiationGO:007147840.015
cell morphogenesisGO:00009022890.015
retina morphogenesis in camera type eyeGO:0060042790.015
negative regulation of signal transduction in absence of ligandGO:190109910.014
multicellular organismal signalingGO:0035637220.014
negative regulation of protein phosphorylationGO:000193340.014
response to steroid hormoneGO:0048545350.014
regionalizationGO:00030022740.014
positive regulation of jak stat cascadeGO:004642720.014
cellular response to nutrient levelsGO:003166920.014
ear developmentGO:00435831270.014
carboxylic acid metabolic processGO:0019752220.014
negative regulation of signal transductionGO:0009968940.014
regulation of cell activationGO:005086510.014
catabolic processGO:0009056320.014
kidney developmentGO:0001822920.014
regulation of programmed cell deathGO:00430671010.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
regulation of myotube differentiationGO:001083020.014
hormone biosynthetic processGO:004244630.014
cellular response to external stimulusGO:007149620.014
fluid transportGO:0042044170.014
regulation of organ growthGO:004662030.014
hepaticobiliary system developmentGO:0061008980.014
regulation of anatomical structure morphogenesisGO:00226031300.014
epithelial cell differentiationGO:00308551160.014
positive regulation of cell divisionGO:005178120.013
epidermal cell fate specificationGO:000995740.013
skeletal system morphogenesisGO:00487051020.013
fatty acid transportGO:001590810.013
cation transportGO:0006812810.013
regulation of cellular component movementGO:0051270550.013
negative regulation of defense responseGO:003134820.013
neuronal action potentialGO:0019228180.013
somatic muscle developmentGO:000752540.013
regulation of cellular ketone metabolic processGO:001056570.013
ventricular cardiac muscle tissue morphogenesisGO:005501020.013
endocrine processGO:005088620.013
response to estrogenGO:0043627270.013
response to abiotic stimulusGO:00096281220.013
positive regulation of metabolic processGO:00098931080.013
water homeostasisGO:003010440.013
gland developmentGO:00487321430.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
regulation of molecular functionGO:0065009700.013
peptidyl lysine acetylationGO:001839420.013
membrane hyperpolarizationGO:006008110.013
regulation of bindingGO:005109830.013
epiboly involved in gastrulation with mouth forming secondGO:0055113350.013
erythrocyte homeostasisGO:0034101550.013
regulation of cellular response to oxidative stressGO:190040720.013
ion transportGO:00068111140.012
regulation of nucleotide catabolic processGO:003081120.012
synaptic growth at neuromuscular junctionGO:005112420.012
p38mapk cascadeGO:003806610.012
female sex differentiationGO:004666040.012
regulation of cell migration involved in sprouting angiogenesisGO:009004930.012
muscle tissue developmentGO:00605371100.012
lipid storageGO:001991510.012
leukocyte proliferationGO:007066110.012
epibolyGO:0090504410.012
lymphocyte proliferationGO:004665110.012
heart processGO:0003015710.012
regulation of cell differentiationGO:00455951420.012
regulation of protein import into nucleusGO:004230620.012
developmental growthGO:00485891660.012
regulation of protein targetingGO:190353320.012
developmental pigmentationGO:0048066480.012
cellular biosynthetic processGO:00442492860.012
transcription dna templatedGO:00063511810.012
regulation of protein ubiquitinationGO:003139630.012
regulation of cell shapeGO:000836010.012
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of response to stimulusGO:00485851040.012
developmental programmed cell deathGO:001062340.012
regulation of nucleocytoplasmic transportGO:004682220.012
regulation of transporter activityGO:003240920.012
female gonad developmentGO:000858540.012
ameboidal type cell migrationGO:00016671430.012
ribonucleoside monophosphate catabolic processGO:000915840.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
internal peptidyl lysine acetylationGO:001839320.012
embryonic heart tube developmentGO:00350501330.012
positive regulation of secretionGO:005104710.012
actin filament based movementGO:003004810.012
localization of cellGO:00516742440.012
positive regulation of endothelial cell proliferationGO:000193810.012
autophagyGO:000691440.012
meiotic nuclear divisionGO:000712640.011
lateral line system developmentGO:0048925760.011
regulation of protein complex assemblyGO:004325430.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of stem cell differentiationGO:200073640.011
protein acylationGO:004354330.011
protein metabolic processGO:00195381830.011
oxidation reduction processGO:0055114410.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
positive regulation of striated muscle cell differentiationGO:005115510.011
protein targeting to nucleusGO:004474430.011
gastrulationGO:00073692080.011
response to topologically incorrect proteinGO:003596620.011
negative regulation of nucleic acid templated transcriptionGO:1903507450.011
retina development in camera type eyeGO:00600411460.011
neural retina developmentGO:0003407490.011
angiogenesisGO:00015251580.011
positive regulation of cell communicationGO:0010647560.011
monocyte differentiationGO:003022420.011
adult behaviorGO:003053420.011
tissue remodelingGO:004877140.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
negative regulation of cell communicationGO:0010648960.011
defense responseGO:0006952470.011
intracellular signal transductionGO:0035556850.011
aromatic compound catabolic processGO:0019439150.011
neural crest cell migrationGO:0001755420.011
regulation of circadian sleep wake cycleGO:004274910.011
positive regulation of developmental processGO:0051094500.011
monovalent inorganic cation transportGO:0015672420.011
response to coldGO:000940940.011
positive regulation of leukocyte differentiationGO:190210710.011
reactive oxygen species biosynthetic processGO:190340910.011
neuromast developmentGO:0048884460.011
regulation of ion transmembrane transporter activityGO:003241220.010
positive regulation of epithelial cell migrationGO:001063420.010
segmentationGO:0035282970.010
positive regulation of secretion by cellGO:190353210.010
endocrine system developmentGO:0035270650.010
regulation of cell cycleGO:0051726520.010
membrane repolarizationGO:008600920.010
locomotory behaviorGO:0007626340.010
i kappab kinase nf kappab signalingGO:000724940.010
cellular response to light stimulusGO:007148240.010
nitric oxide metabolic processGO:004620920.010
positive regulation of signalingGO:0023056560.010
hemopoiesisGO:00300971830.010
negative regulation of protein import into nucleusGO:004230820.010
germ line stem cell maintenanceGO:003071820.010
ribosomal small subunit biogenesisGO:004227420.010
blood circulationGO:0008015870.010
regulation of oocyte developmentGO:006028130.010

bik disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
musculoskeletal system diseaseDOID:1700.016
disease of cellular proliferationDOID:1456600.015
connective tissue diseaseDOID:6500.013
cardiovascular system diseaseDOID:128700.012
nervous system diseaseDOID:86300.011