Danio rerio

64 known processes

cacna1c

calcium channel, voltage-dependent, L type, alpha 1C subunit

(Aliases: C-LTCC,isl)

cacna1c biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system developmentGO:00015011810.626
embryo development ending in birth or egg hatchingGO:00097922710.614
cation transmembrane transportGO:0098655650.537
ion transmembrane transportGO:0034220910.516
regulation of biological qualityGO:00650082630.491
Human Mouse
cellular component morphogenesisGO:00329893360.421
larval developmentGO:000216420.397
chordate embryonic developmentGO:00430092710.378
regulation of multicellular organism growthGO:004001440.341
cellular nitrogen compound biosynthetic processGO:00442712180.337
aromatic compound biosynthetic processGO:00194382170.336
multicellular organism growthGO:003526440.306
inner ear developmentGO:00488391260.300
embryonic heart tube developmentGO:00350501330.297
striated muscle cell differentiationGO:00511461290.283
connective tissue developmentGO:0061448990.269
embryonic skeletal system morphogenesisGO:0048704930.267
hemopoiesisGO:00300971830.225
cellular component biogenesisGO:00440851780.211
skeletal system morphogenesisGO:00487051020.210
determination of bilateral symmetryGO:00098552040.198
Worm
embryonic organ developmentGO:00485683810.189
nucleobase containing compound biosynthetic processGO:00346542050.186
single organism localizationGO:19025782250.185
cellular component assemblyGO:00226071700.179
transmembrane transportGO:00550851200.166
cell morphogenesisGO:00009022890.149
muscle tissue developmentGO:00605371100.146
striated muscle cell developmentGO:00550021080.142
cartilage developmentGO:0051216960.142
embryonic skeletal system developmentGO:0048706970.140
muscle cell differentiationGO:00426921390.138
single organism organelle organizationGO:19025891990.138
heart developmentGO:00075073130.134
cellular localizationGO:0051641970.129
Mouse
cell migrationGO:00164772370.122
regulation of developmental processGO:00507932470.120
Mouse
embryonic organ morphogenesisGO:00485622740.118
enzyme linked receptor protein signaling pathwayGO:00071671060.118
myotube differentiationGO:0014902450.117
myotube cell developmentGO:0014904350.116
single organism transportGO:00447652060.109
sensory organ developmentGO:00074233930.109
immune system processGO:00023762410.104
skeletal muscle tissue developmentGO:0007519670.102
regulation of stem cell differentiationGO:200073640.094
cartilage morphogenesisGO:0060536130.093
ear developmentGO:00435831270.093
gland developmentGO:00487321430.092
regulation of transcription from rna polymerase ii promoterGO:00063571140.091
striated muscle tissue developmentGO:00147061100.089
transportGO:00068102200.089
cell motilityGO:00488702440.086
regulation of transcription dna templatedGO:00063552130.083
heterocycle biosynthetic processGO:00181302150.080
digestive system developmentGO:00551232890.077
specification of symmetryGO:00097992040.077
Worm
establishment of localizationGO:00512342440.076
regulation of localizationGO:00328791040.076
regulation of response to stimulusGO:00485832690.075
Worm
cardiac muscle cell developmentGO:0055013200.073
cellular biosynthetic processGO:00442492860.072
regulation of rna biosynthetic processGO:20011412130.070
muscle structure developmentGO:00610611960.070
regulation of multicellular organismal processGO:00512392770.068
organelle assemblyGO:00709251100.067
cellular component movementGO:00069283350.065
establishment of localization in cellGO:0051649770.065
Mouse
inorganic cation transmembrane transportGO:0098662500.064
regulation of nucleic acid templated transcriptionGO:19035062130.062
endocrine system developmentGO:0035270650.062
positive regulation of nitrogen compound metabolic processGO:0051173690.062
chemotaxisGO:00069351040.062
regulation of cellular biosynthetic processGO:00313262450.061
fin morphogenesisGO:0033334530.059
positive regulation of transportGO:005105020.059
nucleobase containing compound metabolic processGO:00061392740.058
developmental growthGO:00485891660.057
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.055
cell morphogenesis involved in neuron differentiationGO:00486671630.054
cardiac atrium morphogenesisGO:000320920.054
cell projection organizationGO:00300302840.054
mesenchyme developmentGO:00604851270.054
cell part morphogenesisGO:00329902460.054
cell surface receptor signaling pathwayGO:00071663250.052
cognitionGO:005089010.052
Mouse
regulation of biosynthetic processGO:00098892500.051
transcription from rna polymerase ii promoterGO:0006366800.051
signal transductionGO:00071654550.050
organic cyclic compound biosynthetic processGO:19013622230.050
digestive tract morphogenesisGO:00485462310.049
embryonic skeletal joint developmentGO:007249830.049
regulation of neurogenesisGO:0050767870.048
cellular nitrogen compound metabolic processGO:00346412900.047
negative regulation of gene expressionGO:0010629650.047
actin cytoskeleton organizationGO:0030036630.046
muscle organ developmentGO:00075171010.044
stem cell proliferationGO:007208940.043
appendage developmentGO:0048736800.043
neuron projection developmentGO:00311751800.042
blood vessel developmentGO:00015682460.042
regulation of growthGO:0040008420.041
Mouse
regulation of gene expressionGO:00104682650.041
system processGO:00030081850.041
positive regulation of cellular component biogenesisGO:004408930.041
negative regulation of feeding behaviorGO:200025220.041
regulation of protein transportGO:005122330.040
cell proliferationGO:0008283800.040
heart processGO:0003015710.039
hematopoietic or lymphoid organ developmentGO:00485341910.039
heart joggingGO:0003146400.039
maintenance of locationGO:005123540.039
protein complex subunit organizationGO:0071822460.039
ear morphogenesisGO:0042471640.038
regulation of signalingGO:00230512350.038
ameboidal type cell migrationGO:00016671430.038
neuron developmentGO:00486662620.038
response to woundingGO:00096111160.038
embryonic cranial skeleton morphogenesisGO:0048701900.038
tissue homeostasisGO:0001894250.037
immune system developmentGO:00025201910.037
locomotionGO:00400113130.037
generation of neuronsGO:00486993850.037
sensory system developmentGO:0048880760.036
macromolecular complex assemblyGO:0065003350.036
behaviorGO:0007610740.035
Mouse Worm
blood vessel morphogenesisGO:00485142160.035
regulation of organ growthGO:004662030.035
Mouse
muscle fiber developmentGO:0048747520.034
positive regulation of transcription dna templatedGO:0045893570.034
myofibril assemblyGO:0030239480.034
protein complex assemblyGO:0006461300.033
embryonic heart tube morphogenesisGO:00031431080.033
skeletal muscle fiber developmentGO:0048741350.033
cell cell signalingGO:0007267520.032
Mouse
regulation of metabolic processGO:00192223590.032
negative regulation of nucleobase containing compound metabolic processGO:0045934590.032
negative regulation of transcription dna templatedGO:0045892450.032
fin regenerationGO:0031101510.031
regulation of nervous system developmentGO:0051960900.031
lipid storageGO:001991510.031
glial cell differentiationGO:0010001420.031
regulation of reproductive processGO:200024140.031
cellular response to endogenous stimulusGO:0071495680.030
regulation of cell sizeGO:0008361290.030
determination of heart left right asymmetryGO:00613711170.030
pancreas developmentGO:0031016840.030
actin filament based processGO:0030029640.030
regulation of protein complex assemblyGO:004325430.029
regulation of anatomical structure morphogenesisGO:00226031300.029
neuron projection morphogenesisGO:00488121610.029
ion transportGO:00068111140.029
protein importGO:001703830.029
neuron neuron synaptic transmissionGO:000727010.028
tissue regenerationGO:0042246740.028
heart loopingGO:0001947940.028
regulation of nitrogen compound metabolic processGO:00511712510.028
heterocycle metabolic processGO:00464832900.027
regulation of cell differentiationGO:00455951420.027
heart morphogenesisGO:00030071560.027
metal ion transportGO:0030001580.027
cell morphogenesis involved in differentiationGO:00009041950.027
inner ear morphogenesisGO:0042472630.027
regulation of establishment of protein localizationGO:007020140.027
localization of cellGO:00516742440.027
transcription dna templatedGO:00063511810.026
organic substance biosynthetic processGO:19015762890.026
nucleic acid metabolic processGO:00903042440.026
growthGO:00400071740.026
Mouse
embryonic viscerocranium morphogenesisGO:0048703520.026
organelle organizationGO:00069962270.025
negative regulation of biological processGO:00485193040.025
rna metabolic processGO:00160702190.025
axon guidanceGO:0007411860.025
protein localization to nucleusGO:003450430.025
cellular response to organic substanceGO:00713101050.024
cardiac cell fate commitmentGO:006091110.024
cellular component assembly involved in morphogenesisGO:00109271070.024
regulation of behaviorGO:0050795240.023
Worm
negative regulation of rna metabolic processGO:0051253480.023
regulation of protein targetingGO:190353320.023
carbohydrate derivative biosynthetic processGO:1901137430.023
floor plate morphogenesisGO:0033505120.023
cellular response to hormone stimulusGO:0032870390.023
regulation of cell projection organizationGO:0031344440.023
reactive oxygen species metabolic processGO:007259360.022
organic substance transportGO:0071702580.022
Mouse
aorta morphogenesisGO:003590930.022
cellular macromolecule metabolic processGO:00442603910.022
morphogenesis of an epitheliumGO:00020093330.022
response to external stimulusGO:00096052640.022
Zebrafish
neuron differentiationGO:00301823530.022
regulation of rna metabolic processGO:00512522240.022
regulation of cytokine productionGO:000181730.021
reproductive processGO:0022414400.021
Worm
regulation of synapse organizationGO:005080730.021
small molecule metabolic processGO:0044281770.021
negative regulation of signalingGO:0023057960.021
negative regulation of cellular processGO:00485232830.021
regulation of cellular metabolic processGO:00313233200.021
cellular response to oxygen levelsGO:007145310.021
positive regulation of nucleic acid templated transcriptionGO:1903508570.020
neurological system processGO:0050877620.020
Zebrafish Mouse
endocrine pancreas developmentGO:0031018270.020
circulatory system processGO:0003013870.020
regulation of transportGO:0051049450.020
cytoskeleton organizationGO:0007010960.020
digestive tract developmentGO:00485652650.019
pectoral fin developmentGO:0033339500.019
regulation of protein import into nucleusGO:004230620.019
dorsal ventral pattern formationGO:00099531250.019
cellular aromatic compound metabolic processGO:00067252950.019
cytokinesisGO:000091030.019
regulation of protein catabolic processGO:004217610.019
angiogenesisGO:00015251580.019
extracellular structure organizationGO:0043062270.019
carbohydrate homeostasisGO:003350010.019
Mouse
response to alkaloidGO:004327920.019
sensory organ morphogenesisGO:00905962000.019
gene expressionGO:00104672520.019
multi organism processGO:00517041340.019
Worm
rna biosynthetic processGO:00327741810.019
embryonic neurocranium morphogenesisGO:0048702150.019
lateral line developmentGO:0048882660.018
muscle organ morphogenesisGO:004864480.018
nuclear transportGO:005116940.018
cardiogenic plate morphogenesisGO:000314210.018
nitrogen compound metabolic processGO:00068073190.018
biosynthetic processGO:00090582940.018
response to nitrogen compoundGO:1901698190.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
positive regulation of nervous system developmentGO:0051962250.018
endoplasmic reticulum unfolded protein responseGO:003096820.018
cell cycle processGO:0022402530.018
regulation of multicellular organismal developmentGO:20000262230.017
reproductionGO:0000003400.017
Worm
convergent extensionGO:00600261180.017
regulation of transmembrane transportGO:0034762180.017
fin developmentGO:0033333770.017
response to stressGO:00069502630.017
negative regulation of cellular metabolic processGO:0031324770.017
regulation of cell communicationGO:00106462320.017
hatchingGO:003518840.017
vasculature developmentGO:00019442780.016
regulation of cellular component organizationGO:0051128860.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.016
fertilizationGO:000956630.016
regulation of neuron differentiationGO:0045664560.016
positive regulation of developmental processGO:0051094500.016
protein targeting to nucleusGO:004474430.016
single organism metabolic processGO:00447102170.016
somitogenesisGO:0001756870.016
negative regulation of macromolecule metabolic processGO:0010605760.015
regionalizationGO:00030022740.015
cardiac muscle tissue morphogenesisGO:005500870.015
response to endogenous stimulusGO:0009719830.015
eye morphogenesisGO:00485921440.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
regulation of transporter activityGO:003240920.015
multi organism reproductive processGO:0044703360.015
Worm
cardiac chamber morphogenesisGO:0003206120.015
gastrulationGO:00073692080.015
homeostatic processGO:00425921420.015
Human Mouse
negative regulation of developmental processGO:0051093650.015
inorganic ion transmembrane transportGO:0098660570.015
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:004277120.015
regulation of signal transductionGO:00099662250.015
regulation of macromolecule metabolic processGO:00602553170.014
cation transportGO:0006812810.014
stem cell maintenanceGO:001982740.014
cellular response to nutrient levelsGO:003166920.014
developmental programmed cell deathGO:001062340.014
cytosolic calcium ion transportGO:006040130.014
single fertilizationGO:000733830.014
organism emergence from protective structureGO:007168440.014
taxisGO:00423301090.014
regulation of nucleocytoplasmic transportGO:004682220.014
neurotransmitter transportGO:000683620.014
regulation of neuron migrationGO:200122220.014
appendage morphogenesisGO:0035107560.014
negative regulation of reproductive processGO:200024230.013
wound healingGO:0042060900.013
myeloid cell differentiationGO:0030099860.013
regulation of heart contractionGO:0008016320.013
positive regulation of multicellular organismal processGO:0051240520.013
phagocytosisGO:000690930.013
regulation of cytoplasmic transportGO:190364940.013
lateral line system developmentGO:0048925760.013
outflow tract morphogenesisGO:000315110.013
aorta developmentGO:003590440.013
regulation of circadian rhythmGO:004275240.013
eye field cell fate commitment involved in camera type eye formationGO:006089830.013
cellular response to decreased oxygen levelsGO:003629410.013
negative regulation of signal transductionGO:0009968940.013
leukocyte proliferationGO:007066110.013
macromolecular complex subunit organizationGO:0043933740.013
calcium ion transmembrane transportGO:0070588130.013
eye developmentGO:00016542770.013
macromolecule biosynthetic processGO:00090592270.012
protein complex biogenesisGO:0070271300.012
nucleocytoplasmic transportGO:000691340.012
biomineral tissue developmentGO:0031214130.012
positive regulation of cell cycleGO:004578730.012
bmp signaling pathwayGO:0030509520.012
regulation of system processGO:0044057400.012
collagen metabolic processGO:003296320.012
monocarboxylic acid catabolic processGO:007232930.012
astrocyte differentiationGO:004870810.012
embryonic pattern specificationGO:0009880440.012
axon developmentGO:00615641660.012
mesoderm developmentGO:0007498880.012
pectoral fin morphogenesisGO:0035138290.012
compound eye developmentGO:004874920.012
positive regulation of bmp signaling pathwayGO:0030513100.012
single organism cellular localizationGO:1902580460.012
regulation of primary metabolic processGO:00800903110.012
response to organic substanceGO:00100331530.012
muscle cell developmentGO:00550011150.012
meiotic nuclear divisionGO:000712640.012
ventricular cardiac muscle tissue developmentGO:000322930.012
actomyosin structure organizationGO:0031032530.012
positive regulation of cell divisionGO:005178120.012
cardiocyte differentiationGO:0035051440.012
positive regulation of alcohol biosynthetic processGO:190293210.012
regulation of protein localization to nucleusGO:190018020.011
positive regulation of biological processGO:00485182530.011
cellular macromolecule biosynthetic processGO:00346452240.011
regulation of locomotionGO:0040012550.011
cardiac ventricle formationGO:000321110.011
organic cyclic compound metabolic processGO:19013603010.011
cellular response to unfolded proteinGO:003462020.011
regulation of reactive oxygen species metabolic processGO:200037720.011
calcium ion transport into cytosolGO:006040230.011
bmp signaling pathway involved in heart developmentGO:0061312150.011
tube morphogenesisGO:00352393490.011
hormone secretionGO:004687920.011
Mouse
regulation of oocyte developmentGO:006028130.011
regulation of ion transmembrane transporter activityGO:003241220.011
startle responseGO:000196440.011
negative regulation of defense responseGO:003134820.011
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.011
spemann organizer formation at the embryonic shieldGO:006006320.011
oxoacid metabolic processGO:0043436310.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.010
mechanoreceptor differentiationGO:0042490370.010
protein localizationGO:0008104400.010
post embryonic morphogenesisGO:000988640.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.010
organ growthGO:0035265120.010
Mouse
negative regulation of cell differentiationGO:0045596460.010
detection of external stimulusGO:0009581240.010
Zebrafish
single organism nuclear importGO:190259330.010
actin polymerization or depolymerizationGO:000815420.010
floor plate formationGO:0021508120.010

cacna1c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.106
disease of anatomical entityDOID:700.038
Human
bone diseaseDOID:008000100.024
connective tissue diseaseDOID:6500.024
bone development diseaseDOID:008000600.024
musculoskeletal system diseaseDOID:1700.024
cardiovascular system diseaseDOID:128700.018
Human
developmental disorder of mental healthDOID:006003700.010
disease of mental healthDOID:15000.010