Danio rerio

0 known processes

lgi2a

leucine-rich repeat LGI family, member 2a

lgi2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.077
embryonic organ morphogenesisGO:00485622740.055
central nervous system developmentGO:00074173870.053
cell morphogenesisGO:00009022890.052
heterocycle biosynthetic processGO:00181302150.051
neuron differentiationGO:00301823530.049
generation of neuronsGO:00486993850.047
response to external stimulusGO:00096052640.045
cell part morphogenesisGO:00329902460.044
amine metabolic processGO:000930820.043
embryonic organ developmentGO:00485683810.043
cognitionGO:005089010.042
cell projection organizationGO:00300302840.042
aromatic compound biosynthetic processGO:00194382170.041
nitrogen compound metabolic processGO:00068073190.040
cell projection morphogenesisGO:00488582440.039
cellular amine metabolic processGO:004410620.039
regulation of macromolecule metabolic processGO:00602553170.039
adult behaviorGO:003053420.039
positive regulation of transportGO:005105020.038
regulation of multicellular organismal processGO:00512392770.038
larval developmentGO:000216420.038
regulation of metabolic processGO:00192223590.037
regulation of primary metabolic processGO:00800903110.037
negative regulation of biological processGO:00485193040.036
system processGO:00030081850.036
camera type eye developmentGO:00430102220.035
gene expressionGO:00104672520.034
sensory organ developmentGO:00074233930.034
response to stressGO:00069502630.034
maintenance of locationGO:005123540.034
nucleobase containing compound biosynthetic processGO:00346542050.033
regulation of cellular amino acid metabolic processGO:000652100.033
chordate embryonic developmentGO:00430092710.033
positive regulation of erk1 and erk2 cascadeGO:007037420.032
skeletal system developmentGO:00015011810.032
cell motilityGO:00488702440.032
immune system developmentGO:00025201910.032
regulation of cellular ketone metabolic processGO:001056570.032
regulation of cellular metabolic processGO:00313233200.031
organic cyclic compound biosynthetic processGO:19013622230.031
cellular macromolecule metabolic processGO:00442603910.031
signal transductionGO:00071654550.030
locomotionGO:00400113130.030
regulation of gene expressionGO:00104682650.030
cellular component morphogenesisGO:00329893360.030
morphogenesis of an epitheliumGO:00020093330.029
rna metabolic processGO:00160702190.029
response to drugGO:004249330.029
cellular protein catabolic processGO:004425740.029
eye developmentGO:00016542770.028
cation transmembrane transportGO:0098655650.028
heterocycle metabolic processGO:00464832900.028
head developmentGO:00603223030.028
regulation of cellular amine metabolic processGO:003323800.027
neuron projection developmentGO:00311751800.027
positive regulation of biological processGO:00485182530.027
cell morphogenesis involved in differentiationGO:00009041950.027
cellular nitrogen compound metabolic processGO:00346412900.027
brain developmentGO:00074202930.027
cellular component movementGO:00069283350.027
regulation of nucleobase containing compound metabolic processGO:00192192500.027
cellular nitrogen compound biosynthetic processGO:00442712180.027
regulation of nitrogen compound metabolic processGO:00511712510.026
regulation of bindingGO:005109830.026
neuron developmentGO:00486662620.026
multicellular organism growthGO:003526440.026
regulation of establishment of protein localizationGO:007020140.026
nucleic acid metabolic processGO:00903042440.026
regulation of biological qualityGO:00650082630.026
nuclear migrationGO:000709730.025
organic cyclic compound metabolic processGO:19013603010.025
regulation of dendrite morphogenesisGO:004881430.025
regulation of multicellular organismal developmentGO:20000262230.025
regulation of signal transductionGO:00099662250.025
cell migrationGO:00164772370.025
skeletal system morphogenesisGO:00487051020.025
nucleobase containing compound metabolic processGO:00061392740.025
phagocytosisGO:000690930.025
response to chemicalGO:00422213200.025
axonogenesisGO:00074091520.025
transmission of nerve impulseGO:0019226190.025
muscle structure developmentGO:00610611960.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.024
modification dependent protein catabolic processGO:001994130.024
ion transmembrane transportGO:0034220910.024
regulation of metal ion transportGO:001095940.024
regulation of cellular biosynthetic processGO:00313262450.024
regulation of cell communicationGO:00106462320.024
regulation of multicellular organism growthGO:004001440.024
proteasomal protein catabolic processGO:001049820.024
regulation of reproductive processGO:200024140.024
embryonic skeletal system developmentGO:0048706970.023
regulation of protein transportGO:005122330.023
regulation of dendrite developmentGO:005077330.023
carboxylic acid metabolic processGO:0019752220.023
cell morphogenesis involved in neuron differentiationGO:00486671630.023
cellular component biogenesisGO:00440851780.023
cellular biosynthetic processGO:00442492860.023
axon developmentGO:00615641660.023
inorganic cation transmembrane transportGO:0098662500.023
negative regulation of protein phosphorylationGO:000193340.022
extrinsic apoptotic signaling pathwayGO:009719130.022
regulation of membrane potentialGO:0042391230.022
positive regulation of cellular component biogenesisGO:004408930.022
organonitrogen compound metabolic processGO:1901564740.022
cellular amino acid metabolic processGO:000652070.022
cellular response to external stimulusGO:007149620.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
establishment of protein localization to organelleGO:007259440.022
stem cell proliferationGO:007208940.022
transmembrane transportGO:00550851200.022
tube morphogenesisGO:00352393490.022
embryo development ending in birth or egg hatchingGO:00097922710.022
regulation of reactive oxygen species metabolic processGO:200037720.022
negative regulation of cellular processGO:00485232830.022
erk1 and erk2 cascadeGO:007037140.022
macromolecule biosynthetic processGO:00090592270.022
transcription from rna polymerase ii promoterGO:0006366800.022
heart morphogenesisGO:00030071560.021
neuron projection morphogenesisGO:00488121610.021
cellular component assemblyGO:00226071700.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
proteolysis involved in cellular protein catabolic processGO:005160330.020
positive regulation of catabolic processGO:000989640.020
response to nutrientGO:000758430.020
nuclear transportGO:005116940.020
cellular ketone metabolic processGO:0042180110.020
cellular aromatic compound metabolic processGO:00067252950.020
homeostatic processGO:00425921420.020
neuron neuron synaptic transmissionGO:000727010.020
regulation of response to stimulusGO:00485832690.020
regulation of rna metabolic processGO:00512522240.020
organic substance biosynthetic processGO:19015762890.020
positive regulation of cellular catabolic processGO:003133130.019
regulation of synapse assemblyGO:005196330.019
gtp catabolic processGO:000618420.019
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.019
oxoacid metabolic processGO:0043436310.019
response to carbohydrateGO:000974330.019
regulation of cytokine productionGO:000181730.019
regulation of signalingGO:00230512350.019
immune system processGO:00023762410.019
female gonad developmentGO:000858540.019
positive regulation of cell cycleGO:004578730.019
positive regulation of cellular amine metabolic processGO:003324000.019
embryonic skeletal system morphogenesisGO:0048704930.019
gtp metabolic processGO:004603940.019
modification dependent macromolecule catabolic processGO:004363230.019
cell substrate adhesionGO:003158940.019
protein localization to nucleusGO:003450430.019
mitochondrion organizationGO:000700540.018
heart developmentGO:00075073130.018
single organism metabolic processGO:00447102170.018
regulation of developmental processGO:00507932470.018
guanosine containing compound metabolic processGO:190106840.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
ubiquitin dependent protein catabolic processGO:000651130.018
determination of bilateral symmetryGO:00098552040.018
regulation of cytoplasmic transportGO:190364940.018
synaptic transmission cholinergicGO:000727140.018
biosynthetic processGO:00090582940.018
muscle organ developmentGO:00075171010.018
guanosine containing compound catabolic processGO:190106920.018
rna biosynthetic processGO:00327741810.018
regulation of calcium ion transportGO:005192420.017
cation transportGO:0006812810.017
digestive system developmentGO:00551232890.017
transcription dna templatedGO:00063511810.017
organic acid metabolic processGO:0006082310.017
anterior posterior pattern specificationGO:00099521520.017
regulation of tube sizeGO:003515020.017
blood vessel developmentGO:00015682460.017
multicellular organismal signalingGO:0035637220.017
protein metabolic processGO:00195381830.017
digestive tract developmentGO:00485652650.017
protein localization to plasma membraneGO:007265910.016
regulation of protein catabolic processGO:004217610.016
peptide metabolic processGO:000651810.016
autophagyGO:000691440.016
nucleic acid templated transcriptionGO:00976591810.016
cellular response to reactive oxygen speciesGO:003461420.016
nucleocytoplasmic transportGO:000691340.016
response to uvGO:000941130.016
vasculature developmentGO:00019442780.016
cell surface receptor signaling pathwayGO:00071663250.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
negative regulation of protein kinase activityGO:000646940.016
fertilizationGO:000956630.016
regulation of stem cell proliferationGO:007209120.016
notochord developmentGO:0030903540.016
cilium morphogenesisGO:0060271850.016
positive regulation of cytokine productionGO:000181920.016
female sex differentiationGO:004666040.016
response to woundingGO:00096111160.016
synaptic growth at neuromuscular junctionGO:005112420.016
protein targeting to nucleusGO:004474430.016
regulation of sequestering of calcium ionGO:005128240.016
mitotic dna integrity checkpointGO:004477440.015
striated muscle tissue developmentGO:00147061100.015
gastrulationGO:00073692080.015
muscle cell differentiationGO:00426921390.015
development of primary female sexual characteristicsGO:004654540.015
neuronal action potentialGO:0019228180.015
nuclear importGO:005117030.015
regulation of mrna splicing via spliceosomeGO:004802430.015
forebrain cell migrationGO:002188510.015
response to glucocorticoidGO:005138410.015
action potentialGO:0001508190.015
cellular macromolecule biosynthetic processGO:00346452240.015
lipid storageGO:001991510.015
positive regulation of cellular processGO:00485222010.015
central nervous system neuron differentiationGO:0021953740.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
regulation of jak stat cascadeGO:004642530.015
regulation of locomotionGO:0040012550.015
endosomal transportGO:001619720.015
regulation of protein bindingGO:004339330.015
regulation of biosynthetic processGO:00098892500.015
hemopoiesisGO:00300971830.015
localization of cellGO:00516742440.015
response to hydrogen peroxideGO:004254230.015
developmental growth involved in morphogenesisGO:0060560860.015
regulation of cell shapeGO:000836010.015
regulation of epithelial cell proliferationGO:005067830.015
regulation of macromolecule biosynthetic processGO:00105562250.015
cellular response to nutrient levelsGO:003166920.015
protein import into nucleusGO:000660630.015
cilium assemblyGO:0042384580.015
transportGO:00068102200.015
cellular amide metabolic processGO:004360340.014
secondary metabolic processGO:001974830.014
protein dephosphorylationGO:000647030.014
organelle organizationGO:00069962270.014
meiotic nuclear divisionGO:000712640.014
calcium ion transport into cytosolGO:006040230.014
single fertilizationGO:000733830.014
regulation of rna biosynthetic processGO:20011412130.014
positive regulation of secretionGO:005104710.014
response to abiotic stimulusGO:00096281220.014
neurological system processGO:0050877620.014
intracellular signal transductionGO:0035556850.014
regulation of nucleoside metabolic processGO:000911820.014
regulation of transcription dna templatedGO:00063552130.014
regulation of mrna processingGO:005068430.014
cell cycle g2 m phase transitionGO:004483940.014
regulation of protein import into nucleusGO:004230620.014
regulation of ion transmembrane transporter activityGO:003241220.014
multicellular organismal response to stressGO:003355520.014
retina development in camera type eyeGO:00600411460.014
production of molecular mediator of immune responseGO:000244020.014
regulation of blood pressureGO:000821710.014
tissue remodelingGO:004877140.014
establishment of localizationGO:00512342440.014
protein importGO:001703830.014
sequestering of metal ionGO:005123830.014
regenerationGO:0031099910.014
small molecule metabolic processGO:0044281770.014
negative regulation of cell communicationGO:0010648960.014
single organism localizationGO:19025782250.013
regulation of programmed cell deathGO:00430671010.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
exocytosisGO:000688710.013
regulation of protein targetingGO:190353320.013
cytokinesisGO:000091030.013
regulation of synaptic plasticityGO:004816710.013
behaviorGO:0007610740.013
regulation of cell developmentGO:00602841000.013
digestive tract morphogenesisGO:00485462310.013
stem cell divisionGO:001714510.013
regulation of cell deathGO:00109411030.013
response to alkaloidGO:004327920.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
growthGO:00400071740.013
regulation of nucleocytoplasmic transportGO:004682220.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
regulation of synapse organizationGO:005080730.013
regulation of cell substrate adhesionGO:001081010.013
chemosensory behaviorGO:000763510.013
negative regulation of cellular catabolic processGO:003133030.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
cilium organizationGO:0044782710.013
single organism nuclear importGO:190259330.013
response to monosaccharideGO:003428430.013
regulation of cell differentiationGO:00455951420.013
regulation of localizationGO:00328791040.013
regulation of transmembrane transportGO:0034762180.013
regulation of cell activationGO:005086510.013
organelle fusionGO:004828430.013
epithelial tube morphogenesisGO:00605621480.013
cellular response to stressGO:0033554620.013
astrocyte differentiationGO:004870810.013
cell matrix adhesionGO:000716040.013
regulation of purine nucleotide catabolic processGO:003312120.013
peptidyl serine phosphorylationGO:001810510.013
response to corticosteroidGO:003196010.013
cellular component disassemblyGO:002241110.013
central nervous system neuron developmentGO:0021954290.013
protein targeting to membraneGO:000661210.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of erk1 and erk2 cascadeGO:007037240.012
hepaticobiliary system developmentGO:0061008980.012
inorganic ion transmembrane transportGO:0098660570.012
adherens junction organizationGO:003433240.012
sequestering of calcium ionGO:005120830.012
muscle tissue developmentGO:00605371100.012
mechanosensory behaviorGO:000763820.012
regulation of protein complex assemblyGO:004325430.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
membrane invaginationGO:001032410.012
metal ion transportGO:0030001580.012
positive regulation of myeloid cell differentiationGO:004563920.012
cellular protein modification processGO:00064641000.012
positive regulation of cell adhesionGO:004578510.012
somite developmentGO:0061053960.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
maternal determination of anterior posterior axis embryoGO:000835840.012
muscle cell developmentGO:00550011150.012
ear developmentGO:00435831270.012
centrosome organizationGO:005129710.012
phosphate containing compound metabolic processGO:00067961080.012
olfactory bulb developmentGO:002177240.012
embryonic heart tube developmentGO:00350501330.012
programmed cell deathGO:00125011190.012
synaptic vesicle transportGO:004848910.012
meiotic cell cycle processGO:190304630.012
protein heterooligomerizationGO:005129110.012
connective tissue developmentGO:0061448990.012
cellular protein metabolic processGO:00442671290.012
regionalizationGO:00030022740.012
sensory perception of painGO:001923310.012
negative regulation of kinase activityGO:003367340.012
peptidyl serine modificationGO:001820920.012
protein stabilizationGO:005082120.011
regulation of protein localization to nucleusGO:190018020.011
olfactory lobe developmentGO:002198840.011
positive regulation of secretion by cellGO:190353210.011
sensory perception of chemical stimulusGO:000760630.011
response to endogenous stimulusGO:0009719830.011
regulation of neurogenesisGO:0050767870.011
actin filament based movementGO:003004810.011
macromolecule modificationGO:00434121110.011
cellular response to radiationGO:007147840.011
positive regulation of cytoskeleton organizationGO:005149530.011
myeloid cell differentiationGO:0030099860.011
developmental programmed cell deathGO:001062340.011
protein acylationGO:004354330.011
regulation of gtp catabolic processGO:003312420.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
specification of symmetryGO:00097992040.011
phosphorus metabolic processGO:00067931090.011
gland developmentGO:00487321430.011
cell cycle arrestGO:000705010.011
liver developmentGO:0001889960.011
positive regulation of metabolic processGO:00098931080.011
establishment of protein localization to plasma membraneGO:009000210.011
antimicrobial humoral responseGO:001973020.011
negative regulation of response to stimulusGO:00485851040.011
regulation of nucleotide catabolic processGO:003081120.011
regulation of blood vessel sizeGO:005088020.011
regulation of neuron differentiationGO:0045664560.011
regulation of intracellular protein transportGO:003315730.011
carbohydrate biosynthetic processGO:001605110.011
forebrain developmentGO:0030900960.011
regulation of inflammatory responseGO:005072720.011
single organism membrane fusionGO:004480120.011
locomotory behaviorGO:0007626340.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
positive regulation of leukocyte differentiationGO:190210710.010
positive regulation of multicellular organismal processGO:0051240520.010
stem cell maintenanceGO:001982740.010
nuclear exportGO:005116810.010
smooth muscle contractionGO:000693920.010
determination of left right symmetryGO:00073681790.010
negative regulation of catabolic processGO:000989530.010
embryonic hemopoiesisGO:0035162530.010
inositol lipid mediated signalingGO:004801720.010
positive regulation of epithelial cell migrationGO:001063420.010
regulation of systemic arterial blood pressureGO:000307310.010
regulation of anatomical structure morphogenesisGO:00226031300.010
peptidyl lysine acetylationGO:001839420.010
negative regulation of cytokine productionGO:000181810.010
microtubule organizing center organizationGO:003102310.010
sensory system developmentGO:0048880760.010
post golgi vesicle mediated transportGO:000689210.010
developmental growthGO:00485891660.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
neuromuscular synaptic transmissionGO:000727420.010
atp catabolic processGO:000620040.010
rna localizationGO:000640340.010
sensory organ morphogenesisGO:00905962000.010
response to organic substanceGO:00100331530.010
organelle assemblyGO:00709251100.010
response to hexoseGO:000974630.010
multi organism processGO:00517041340.010
b cell activationGO:004211320.010

lgi2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
immune system diseaseDOID:291400.018
cardiovascular system diseaseDOID:128700.017
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
nervous system diseaseDOID:86300.016
organ system cancerDOID:005068600.013
eye and adnexa diseaseDOID:149200.013
sensory system diseaseDOID:005015500.013
disease of metabolismDOID:001466700.013