Danio rerio

0 known processes

gc3

guanylyl cyclase 3

(Aliases: GUCY2d1,RETGC-3)

gc3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
photoreceptor cell outer segment organizationGO:003584590.939
Zebrafish
phototransduction visible lightGO:000760320.910
rhodopsin mediated signaling pathwayGO:001605610.895
visual perceptionGO:0007601170.889
Zebrafish
response to light stimulusGO:0009416460.847
phototransductionGO:000760220.750
sensory perception of light stimulusGO:0050953190.706
Zebrafish
cellular response to radiationGO:007147840.667
detection of visible lightGO:0009584120.662
detection of light stimulusGO:0009583120.655
camera type eye developmentGO:00430102220.613
detection of external stimulusGO:0009581240.611
eye developmentGO:00016542770.605
regulation of guanylate cyclase activityGO:003128260.586
response to abiotic stimulusGO:00096281220.556
detection of stimulusGO:0051606290.552
retina development in camera type eyeGO:00600411460.513
absorption of visible lightGO:001603820.485
light absorptionGO:001603720.455
cgmp metabolic processGO:004606870.409
Zebrafish Rat
neural retina developmentGO:0003407490.377
regulation of biological qualityGO:00650082630.369
retina homeostasisGO:0001895120.355
camera type eye morphogenesisGO:00485931080.339
response to external stimulusGO:00096052640.333
small molecule metabolic processGO:0044281770.321
Zebrafish Rat
retina layer formationGO:0010842240.314
sensory organ developmentGO:00074233930.313
photoperiodismGO:0009648110.294
response to radiationGO:0009314510.283
detection of abiotic stimulusGO:0009582240.273
transportGO:00068102200.270
photoreceptor cell differentiationGO:0046530550.265
Zebrafish
entrainment of circadian clock by photoperiodGO:004315310.225
positive regulation of cgmp biosynthetic processGO:003082860.214
light induced release of internally sequestered calcium ionGO:000837710.205
retina morphogenesis in camera type eyeGO:0060042790.203
regulation of localizationGO:00328791040.195
signal transductionGO:00071654550.175
camera type eye photoreceptor cell differentiationGO:0060219190.172
central nervous system developmentGO:00074173870.154
system processGO:00030081850.152
Zebrafish
digestive tract morphogenesisGO:00485462310.151
apical junction assemblyGO:004329710.133
eye morphogenesisGO:00485921440.130
regulation of primary metabolic processGO:00800903110.127
behaviorGO:0007610740.118
regulation of axonogenesisGO:0050770320.115
stem cell divisionGO:001714510.109
meiotic nuclear divisionGO:000712640.108
generation of neuronsGO:00486993850.106
Zebrafish
neurological system processGO:0050877620.105
Zebrafish
response to light intensityGO:000964210.103
brain developmentGO:00074202930.102
positive regulation of guanylate cyclase activityGO:003128460.095
organic cyclic compound biosynthetic processGO:19013622230.094
Zebrafish Rat
cellular nitrogen compound metabolic processGO:00346412900.094
Zebrafish Rat
nucleobase containing compound metabolic processGO:00061392740.092
Zebrafish Rat
light adaptionGO:003636710.091
agingGO:000756820.091
cell migration involved in heart developmentGO:0060973220.087
inner ear receptor cell fate commitmentGO:006012040.087
larval developmentGO:000216420.085
protein modification processGO:00362111000.085
locomotionGO:00400113130.084
response to stressGO:00069502630.082
spindle assemblyGO:005122520.081
regulation of circadian sleep wake cycleGO:004274910.079
heterocycle biosynthetic processGO:00181302150.078
Zebrafish Rat
positive regulation of cgmp metabolic processGO:003082560.078
regulation of neurotransmitter secretionGO:004692810.077
heart developmentGO:00075073130.076
lipid storageGO:001991510.075
organic cyclic compound metabolic processGO:19013603010.074
Zebrafish Rat
developmental growthGO:00485891660.074
cellular component movementGO:00069283350.074
digestive tract developmentGO:00485652650.073
heterocycle metabolic processGO:00464832900.073
Zebrafish Rat
regulation of inflammatory responseGO:005072720.072
taxisGO:00423301090.072
maintenance of locationGO:005123540.072
regulation of cgmp biosynthetic processGO:003082660.070
cellular macromolecule metabolic processGO:00442603910.069
skeletal system developmentGO:00015011810.069
gastrulationGO:00073692080.068
locomotory behaviorGO:0007626340.067
endothelium developmentGO:0003158250.066
response to chemicalGO:00422213200.065
regulation of smoothened signaling pathwayGO:0008589180.064
regulation of cgmp metabolic processGO:003082360.064
cellular response to light stimulusGO:007148240.064
single organism localizationGO:19025782250.064
regulation of signalingGO:00230512350.063
neuron developmentGO:00486662620.061
Zebrafish
cortical cytoskeleton organizationGO:003086510.060
anatomical structure homeostasisGO:0060249360.060
g protein coupled receptor signaling pathwayGO:0007186740.059
gene expressionGO:00104672520.058
nucleic acid metabolic processGO:00903042440.058
response to drugGO:004249330.056
cell morphogenesis involved in neuron differentiationGO:00486671630.055
organonitrogen compound metabolic processGO:1901564740.054
Zebrafish Rat
cell projection organizationGO:00300302840.054
Zebrafish
cellular amine metabolic processGO:004410620.054
growthGO:00400071740.052
response to osmotic stressGO:0006970110.051
organelle organizationGO:00069962270.051
Zebrafish
neuroblast proliferationGO:000740520.051
neuron differentiationGO:00301823530.050
Zebrafish
chemotaxisGO:00069351040.050
muscle structure developmentGO:00610611960.050
medial fin developmentGO:0033338160.048
stem cell proliferationGO:007208940.048
epibolyGO:0090504410.048
embryo development ending in birth or egg hatchingGO:00097922710.047
nucleocytoplasmic transportGO:000691340.046
polyol metabolic processGO:001975110.046
regulation of sequestering of calcium ionGO:005128240.045
polarized epithelial cell differentiationGO:003085940.045
transmission of nerve impulseGO:0019226190.045
hematopoietic or lymphoid organ developmentGO:00485341910.045
regulation of cellular amine metabolic processGO:003323800.044
regulation of neurogenesisGO:0050767870.044
ribonucleotide biosynthetic processGO:0009260200.044
Zebrafish Rat
action potentialGO:0001508190.043
nuclear transportGO:005116940.043
chordate embryonic developmentGO:00430092710.043
locomotor rhythmGO:004547530.041
sensory organ morphogenesisGO:00905962000.041
neuron neuron synaptic transmissionGO:000727010.041
cell growthGO:0016049570.041
nucleotide biosynthetic processGO:0009165210.040
Zebrafish Rat
negative regulation of protein phosphorylationGO:000193340.040
phosphorus metabolic processGO:00067931090.039
Zebrafish Rat
regulation of muscle contractionGO:000693730.039
epithelial cell developmentGO:0002064420.039
establishment of localizationGO:00512342440.039
cyclic purine nucleotide metabolic processGO:0052652180.039
Zebrafish Rat
regulation of neuron differentiationGO:0045664560.038
optokinetic behaviorGO:000763490.038
receptor recyclingGO:000188140.037
cellular component morphogenesisGO:00329893360.037
nucleobase containing compound biosynthetic processGO:00346542050.037
Zebrafish Rat
neuron projection developmentGO:00311751800.036
single organism transportGO:00447652060.036
neurotransmitter transportGO:000683620.035
cellular biosynthetic processGO:00442492860.035
Zebrafish Rat
multicellular organism growthGO:003526440.034
regulation of macromolecule metabolic processGO:00602553170.034
regulation of circadian sleep wake cycle sleepGO:004518710.034
endothelial cell differentiationGO:0045446200.033
regulation of cellular ketone metabolic processGO:001056570.033
meiotic cell cycle processGO:190304630.033
sequestering of metal ionGO:005123830.032
homeostatic processGO:00425921420.031
cellular nitrogen compound biosynthetic processGO:00442712180.031
Zebrafish Rat
cardiogenic plate morphogenesisGO:000314210.031
multicellular organismal signalingGO:0035637220.031
regulation of extent of cell growthGO:0061387290.031
entrainment of circadian clockGO:000964920.030
regulation of protein modification by small protein conjugation or removalGO:190332030.030
immune system developmentGO:00025201910.030
cell fate commitmentGO:0045165990.030
biosynthetic processGO:00090582940.029
Zebrafish Rat
positive regulation of lyase activityGO:005134960.029
negative regulation of biological processGO:00485193040.029
regulation of bindingGO:005109830.029
cognitionGO:005089010.029
positive regulation of transportGO:005105020.029
hemopoiesisGO:00300971830.029
localization of cellGO:00516742440.029
purine nucleotide biosynthetic processGO:0006164200.029
Zebrafish Rat
embryonic organ morphogenesisGO:00485622740.029
apical protein localizationGO:004517660.028
ion transmembrane transportGO:0034220910.027
protein modification by small protein removalGO:007064610.027
regulation of cell differentiationGO:00455951420.027
amine metabolic processGO:000930820.027
ion transportGO:00068111140.026
regulation of cell developmentGO:00602841000.026
cellular localizationGO:0051641970.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
axon regenerationGO:0031103140.026
immune system processGO:00023762410.026
regulation of nucleic acid templated transcriptionGO:19035062130.026
modification dependent macromolecule catabolic processGO:004363230.025
circadian sleep wake cycleGO:004274520.025
protein desumoylationGO:001692610.025
proteolysis involved in cellular protein catabolic processGO:005160330.025
circadian rhythmGO:0007623190.025
embryonic skeletal joint developmentGO:007249830.024
photoreceptor cell maintenanceGO:0045494110.024
regulation of growth rateGO:004000910.024
regulation of growthGO:0040008420.024
olfactory bulb developmentGO:002177240.024
response to woundingGO:00096111160.024
positive regulation of muscle organ developmentGO:004863610.024
modification dependent protein catabolic processGO:001994130.024
single organism biosynthetic processGO:0044711710.023
Zebrafish Rat
purine ribonucleotide biosynthetic processGO:0009152200.023
Zebrafish Rat
cell surface receptor signaling pathwayGO:00071663250.023
regulation of molecular functionGO:0065009700.023
rna biosynthetic processGO:00327741810.023
dorsal motor nucleus of vagus nerve developmentGO:002174440.023
regulation of cell communicationGO:00106462320.022
regulation of gene expressionGO:00104682650.022
auditory receptor cell fate determinationGO:004266820.022
axon guidanceGO:0007411860.022
regulation of membrane potentialGO:0042391230.022
neural precursor cell proliferationGO:0061351200.022
olfactory lobe developmentGO:002198840.022
embryonic heart tube formationGO:000314410.022
regulation of response to stimulusGO:00485832690.021
cgmp biosynthetic processGO:000618270.021
Zebrafish Rat
cellular component assembly involved in morphogenesisGO:00109271070.021
digestive system developmentGO:00551232890.021
meiotic chromosome segregationGO:004513230.021
regulation of multicellular organism growthGO:004001440.021
developmental growth involved in morphogenesisGO:0060560860.021
detection of stimulus involved in sensory perceptionGO:0050906210.021
single organism metabolic processGO:00447102170.021
Zebrafish Rat
cellular amino acid metabolic processGO:000652070.021
cellular aromatic compound metabolic processGO:00067252950.021
Zebrafish Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
purine containing compound biosynthetic processGO:0072522200.020
Zebrafish Rat
regulation of cell sizeGO:0008361290.020
regulation of nucleocytoplasmic transportGO:004682220.020
cortical actin cytoskeleton organizationGO:003086610.020
circadian sleep wake cycle sleepGO:005080210.020
calcium ion homeostasisGO:0055074190.020
protein localizationGO:0008104400.020
regulation of myotube differentiationGO:001083020.020
circulatory system processGO:0003013870.020
cation transmembrane transportGO:0098655650.020
adult behaviorGO:003053420.019
protein metabolic processGO:00195381830.019
protein polymerizationGO:005125840.019
sleepGO:003043110.019
cellular ketone metabolic processGO:0042180110.019
embryonic heart tube developmentGO:00350501330.019
digestive tract mesoderm developmentGO:000750210.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of intracellular protein transportGO:003315730.018
reproductionGO:0000003400.018
negative regulation of defense responseGO:003134820.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
macromolecule modificationGO:00434121110.018
embryonic skeletal system morphogenesisGO:0048704930.018
epithelial cell differentiationGO:00308551160.018
photoreceptor cell developmentGO:0042461400.018
Zebrafish
actin polymerization or depolymerizationGO:000815420.018
retinal pigment epithelium developmentGO:000340680.018
negative regulation of sequestering of calcium ionGO:005128340.017
anterior lateral line nerve developmentGO:004890940.017
establishment of cell polarityGO:0030010180.017
muscle cell differentiationGO:00426921390.017
regulation of establishment of protein localizationGO:007020140.017
eye photoreceptor cell differentiationGO:0001754450.017
regulation of axon extensionGO:0030516240.017
establishment of spindle localizationGO:0051293120.017
endocardium formationGO:006021410.017
fin morphogenesisGO:0033334530.017
positive regulation of biological processGO:00485182530.017
smoothened signaling pathwayGO:0007224300.017
regulation of stem cell differentiationGO:200073640.016
rho protein signal transductionGO:000726650.016
sensory perceptionGO:0007600390.016
Zebrafish
dna biosynthetic processGO:007189730.016
cyclic nucleotide metabolic processGO:0009187180.016
Zebrafish Rat
regulation of anatomical structure morphogenesisGO:00226031300.016
transmembrane transportGO:00550851200.016
multicellular organismal response to stressGO:003355520.016
regulation of catalytic activityGO:0050790550.016
somite developmentGO:0061053960.016
cellular protein catabolic processGO:004425740.016
neuron projection guidanceGO:0097485860.016
inflammatory responseGO:000695480.016
wound healingGO:0042060900.016
developmental cell growthGO:0048588520.016
sequestering of calcium ionGO:005120830.016
organelle assemblyGO:00709251100.016
regulation of protein bindingGO:004339330.015
regenerationGO:0031099910.015
negative regulation of signal transductionGO:0009968940.015
axon extensionGO:0048675450.015
circadian sleep wake cycle processGO:002241020.015
organic substance biosynthetic processGO:19015762890.015
Zebrafish Rat
regulation of multicellular organismal processGO:00512392770.015
embryonic organ developmentGO:00485683810.015
embryonic hemopoiesisGO:0035162530.015
negative regulation of kinase activityGO:003367340.015
macromolecule localizationGO:0033036540.015
glucocorticoid metabolic processGO:000821120.015
tissue regenerationGO:0042246740.015
retinal cone cell differentiationGO:0042670120.014
sensory perception of chemical stimulusGO:000760630.014
phagocytosisGO:000690930.014
cell cycleGO:0007049930.014
cellular protein metabolic processGO:00442671290.014
regulation of rna biosynthetic processGO:20011412130.014
negative regulation of cellular metabolic processGO:0031324770.014
cellular component assemblyGO:00226071700.014
lymphatic endothelial cell fate commitmentGO:006083810.014
regulation of transmembrane transportGO:0034762180.014
positive regulation of striated muscle tissue developmentGO:004584410.014
muscle cell developmentGO:00550011150.014
appendage developmentGO:0048736800.014
defense responseGO:0006952470.014
establishment of synaptic vesicle localizationGO:009748010.013
medial fin morphogenesisGO:0035141140.013
actomyosin structure organizationGO:0031032530.013
axonogenesisGO:00074091520.013
regulation of protein metabolic processGO:0051246560.013
regulation of neurotransmitter transportGO:005158810.013
single organismal cell cell adhesionGO:0016337290.013
embryonic skeletal joint morphogenesisGO:006027230.013
ion homeostasisGO:0050801410.013
regulation of cytoplasmic transportGO:190364940.013
swimming behaviorGO:003626980.013
spermatid developmentGO:000728620.013
regulation of interferon gamma mediated signaling pathwayGO:006033410.013
regulation of cellular amino acid metabolic processGO:000652100.013
ear developmentGO:00435831270.013
striated muscle cell differentiationGO:00511461290.013
macromolecule biosynthetic processGO:00090592270.013
skeletal system morphogenesisGO:00487051020.013
convergent extensionGO:00600261180.013
retinal cone cell developmentGO:004654980.013
regulation of cellular component organizationGO:0051128860.013
hindbrain developmentGO:0030902910.012
mrna stabilizationGO:004825540.012
metal ion homeostasisGO:0055065260.012
response to amineGO:001407510.012
vasculature developmentGO:00019442780.012
response to uvGO:000941130.012
cell cell signalingGO:0007267520.012
negative regulation of secretionGO:005104820.012
regulation of cellular biosynthetic processGO:00313262450.012
cellular response to abiotic stimulusGO:007121440.012
cellular response to nutrient levelsGO:003166920.012
spermatid differentiationGO:004851520.012
organic acid metabolic processGO:0006082310.012
centrosome organizationGO:005129710.012
positive regulation of cell divisionGO:005178120.012
regulation of circadian rhythmGO:004275240.012
regulation of protein polymerizationGO:003227120.012
ribose phosphate biosynthetic processGO:0046390200.012
Zebrafish Rat
thermosensory behaviorGO:004004010.012
response to temperature stimulusGO:0009266150.012
inositol lipid mediated signalingGO:004801720.012
axon developmentGO:00615641660.012
positive regulation of cell cycleGO:004578730.012
establishment of organelle localizationGO:0051656450.012
eye photoreceptor cell developmentGO:0042462300.012
positive regulation of translationGO:004572710.012
response to corticosteroidGO:003196010.012
head developmentGO:00603223030.012
regulation of receptor recyclingGO:000191930.012
positive regulation of cell differentiationGO:0045597300.012
organism emergence from protective structureGO:007168440.012
transition metal ion transportGO:000004160.012
cell projection assemblyGO:0030031640.011
endocrine system developmentGO:0035270650.011
protein depolymerizationGO:005126110.011
ubiquitin dependent protein catabolic processGO:000651130.011
regulation of nervous system developmentGO:0051960900.011
cell deathGO:00082191210.011
carbohydrate derivative metabolic processGO:1901135610.011
Zebrafish Rat
negative regulation of signalingGO:0023057960.011
response to vitaminGO:003327330.011
programmed cell deathGO:00125011190.011
guanosine containing compound metabolic processGO:190106840.011
regulation of protein transportGO:005122330.011
fertilizationGO:000956630.011
regionalizationGO:00030022740.011
response to amino acidGO:004320020.011
regulation of cell activationGO:005086510.011
mononuclear cell proliferationGO:003294310.011
endothelial cell developmentGO:0001885120.011
nuclear importGO:005117030.011
inositol phosphate metabolic processGO:004364710.011
cellular response to stressGO:0033554620.011
regulation of skeletal muscle fiber developmentGO:004874220.011
cellular response to extracellular stimulusGO:003166820.011
anterior posterior pattern specificationGO:00099521520.011
regulation of cell morphogenesis involved in differentiationGO:0010769380.011
one carbon compound transportGO:0019755140.011
microtubule based processGO:0007017600.011
caudal fin morphogenesisGO:003514370.011
phosphate containing compound metabolic processGO:00067961080.010
Zebrafish Rat
neuron projection extension involved in neuron projection guidanceGO:1902284100.010
female meiotic divisionGO:000714320.010
rhythmic processGO:0048511210.010
cellular protein modification processGO:00064641000.010
regulation of wnt signaling pathwayGO:0030111530.010
mitotic cell cycle processGO:1903047480.010
regulation of purine nucleotide catabolic processGO:003312120.010
nitrogen compound metabolic processGO:00068073190.010
Zebrafish Rat
establishment of epithelial cell polarityGO:009016220.010
organelle localizationGO:0051640490.010
exocrine pancreas developmentGO:0031017280.010
neuron projection morphogenesisGO:00488121610.010
carbohydrate derivative biosynthetic processGO:1901137430.010
Zebrafish Rat
protein phosphorylationGO:0006468470.010
blood vessel developmentGO:00015682460.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
negative regulation of macromolecule metabolic processGO:0010605760.010
regulation of metal ion transportGO:001095940.010
regulation of lyase activityGO:0051339120.010

gc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.194
Human
eye and adnexa diseaseDOID:149200.194
Human
disease of anatomical entityDOID:700.194
Human
nervous system diseaseDOID:86300.194
Human
eye diseaseDOID:561400.194
Human
retinal diseaseDOID:567900.194
Human
disease of metabolismDOID:001466700.047
inherited metabolic disorderDOID:65500.047
retinal degenerationDOID:846600.021