Danio rerio

29 known processes

dot1l

DOT1-like, histone H3 methyltransferase (S. cerevisiae)

(Aliases: si:dkey-211f22.1)

dot1l biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.112
agingGO:000756820.064
heterocycle biosynthetic processGO:00181302150.060
sensory organ developmentGO:00074233930.053
cellular biosynthetic processGO:00442492860.050
embryonic organ developmentGO:00485683810.050
nucleobase containing compound biosynthetic processGO:00346542050.049
signal transductionGO:00071654550.049
biosynthetic processGO:00090582940.047
cell surface receptor signaling pathwayGO:00071663250.045
cellular macromolecule biosynthetic processGO:00346452240.044
cellular protein catabolic processGO:004425740.043
regulation of biosynthetic processGO:00098892500.043
nucleic acid templated transcriptionGO:00976591810.042
regulation of primary metabolic processGO:00800903110.042
nuclear transportGO:005116940.042
cellular response to external stimulusGO:007149620.041
organic substance biosynthetic processGO:19015762890.040
response to chemicalGO:00422213200.040
positive regulation of transportGO:005105020.040
regulation of cellular biosynthetic processGO:00313262450.039
cellular macromolecule metabolic processGO:00442603910.039
phagocytosisGO:000690930.038
stem cell maintenanceGO:001982740.038
heart developmentGO:00075073130.038
maintenance of locationGO:005123540.038
regulation of multicellular organism growthGO:004001440.037
aromatic compound biosynthetic processGO:00194382170.037
tube morphogenesisGO:00352393490.036
nucleic acid metabolic processGO:00903042440.036
regulation of establishment of protein localizationGO:007020140.036
regulation of cellular metabolic processGO:00313233200.035
regulation of nitrogen compound metabolic processGO:00511712510.035
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.035
chordate embryonic developmentGO:00430092710.035
establishment of protein localization to organelleGO:007259440.034
gene expressionGO:00104672520.034
immune system developmentGO:00025201910.034
nitrogen compound metabolic processGO:00068073190.033
regulation of cytokine productionGO:000181730.033
regulation of macromolecule metabolic processGO:00602553170.033
immune system processGO:00023762410.033
regulation of response to stimulusGO:00485832690.033
proteolysis involved in cellular protein catabolic processGO:005160330.032
morphogenesis of an epitheliumGO:00020093330.032
organic cyclic compound biosynthetic processGO:19013622230.032
multicellular organism growthGO:003526440.031
central nervous system developmentGO:00074173870.031
cellular response to nutrient levelsGO:003166920.031
amine metabolic processGO:000930820.031
cellular response to extracellular stimulusGO:003166820.031
organic cyclic compound metabolic processGO:19013603010.031
regulation of metabolic processGO:00192223590.031
response to external stimulusGO:00096052640.031
heterocycle metabolic processGO:00464832900.030
regulation of protein catabolic processGO:004217610.030
cellular aromatic compound metabolic processGO:00067252950.030
brain developmentGO:00074202930.030
nucleocytoplasmic transportGO:000691340.030
proteasomal protein catabolic processGO:001049820.030
lipid storageGO:001991510.030
rna metabolic processGO:00160702190.030
response to stressGO:00069502630.030
head developmentGO:00603223030.030
cellular nitrogen compound metabolic processGO:00346412900.029
regulation of transcription dna templatedGO:00063552130.029
digestive system developmentGO:00551232890.029
gland developmentGO:00487321430.029
embryonic organ morphogenesisGO:00485622740.029
regulation of signal transductionGO:00099662250.029
macromolecule biosynthetic processGO:00090592270.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
regulation of biological qualityGO:00650082630.029
peptide transportGO:001583310.029
regulation of production of molecular mediator of immune responseGO:000270010.028
development of primary female sexual characteristicsGO:004654540.028
transportGO:00068102200.028
positive regulation of catabolic processGO:000989640.028
transcription dna templatedGO:00063511810.028
regulation of rna metabolic processGO:00512522240.028
single organism nuclear importGO:190259330.028
modification dependent macromolecule catabolic processGO:004363230.028
eye developmentGO:00016542770.027
protein localization to nucleusGO:003450430.027
modification dependent protein catabolic processGO:001994130.027
rna biosynthetic processGO:00327741810.027
regulation of nucleic acid templated transcriptionGO:19035062130.027
female sex differentiationGO:004666040.027
positive regulation of cellular catabolic processGO:003133130.027
regulation of gene expressionGO:00104682650.027
meiotic nuclear divisionGO:000712640.027
cellular component morphogenesisGO:00329893360.027
response to carbohydrateGO:000974330.026
vasculature developmentGO:00019442780.026
positive regulation of cell cycleGO:004578730.026
digestive tract developmentGO:00485652650.026
response to uvGO:000941130.026
cellular component movementGO:00069283350.026
protein targeting to nucleusGO:004474430.026
cellular carbohydrate metabolic processGO:004426240.026
nucleobase containing compound metabolic processGO:00061392740.026
regulation of macromolecule biosynthetic processGO:00105562250.025
regulation of cell activationGO:005086510.025
establishment of localizationGO:00512342440.025
generation of neuronsGO:00486993850.025
cell morphogenesisGO:00009022890.025
ubiquitin dependent protein catabolic processGO:000651130.025
regulation of multicellular organismal processGO:00512392770.025
positive regulation of biological processGO:00485182530.025
negative regulation of protein phosphorylationGO:000193340.025
determination of left right symmetryGO:00073681790.024
regulation of protein localization to nucleusGO:190018020.024
protein import into nucleusGO:000660630.024
negative regulation of biological processGO:00485193040.024
autophagyGO:000691440.024
protein importGO:001703830.024
hemopoiesisGO:00300971830.024
regulation of protein transportGO:005122330.024
nuclear importGO:005117030.024
response to drugGO:004249330.023
regulation of cell shapeGO:000836010.023
regulation of rna biosynthetic processGO:20011412130.023
female gonad developmentGO:000858540.023
peptidyl lysine acetylationGO:001839420.023
regulation of cell communicationGO:00106462320.023
negative regulation of protein serine threonine kinase activityGO:007190120.023
hormone transportGO:000991420.023
regulation of cellular ketone metabolic processGO:001056570.023
neuron differentiationGO:00301823530.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
digestive tract morphogenesisGO:00485462310.022
regulation of protein complex assemblyGO:004325430.022
regulation of protein import into nucleusGO:004230620.022
cellular response to starvationGO:000926710.022
response to organic substanceGO:00100331530.022
specification of symmetryGO:00097992040.022
regulation of cytoplasmic transportGO:190364940.022
cellular amine metabolic processGO:004410620.022
leukocyte proliferationGO:007066110.022
hormone secretionGO:004687920.022
response to monosaccharideGO:003428430.022
cellular ketone metabolic processGO:0042180110.022
gastrulationGO:00073692080.022
locomotionGO:00400113130.021
rna localizationGO:000640340.021
positive regulation of cytokine productionGO:000181920.021
protein metabolic processGO:00195381830.021
meiotic chromosome segregationGO:004513230.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.021
actin polymerization or depolymerizationGO:000815420.021
single organism localizationGO:19025782250.021
negative regulation of cellular processGO:00485232830.021
transcription from rna polymerase ii promoterGO:0006366800.021
blood vessel developmentGO:00015682460.021
antimicrobial humoral responseGO:001973020.021
positive regulation of cellular component biogenesisGO:004408930.021
cell projection morphogenesisGO:00488582440.020
blood vessel morphogenesisGO:00485142160.020
determination of bilateral symmetryGO:00098552040.020
regulation of synapse assemblyGO:005196330.020
oxoacid metabolic processGO:0043436310.020
cellular amide metabolic processGO:004360340.020
cellular response to organic substanceGO:00713101050.020
regulation of nucleocytoplasmic transportGO:004682220.020
regulation of signalingGO:00230512350.020
regulation of inflammatory responseGO:005072720.020
regulation of intracellular protein transportGO:003315730.020
embryonic skeletal system developmentGO:0048706970.020
internal protein amino acid acetylationGO:000647520.020
membrane invaginationGO:001032410.020
lymphocyte proliferationGO:004665110.020
mitochondrion organizationGO:000700540.020
cellular response to lipopolysaccharideGO:007122230.020
response to glucoseGO:000974930.020
response to hexoseGO:000974630.020
embryo development ending in birth or egg hatchingGO:00097922710.020
stem cell proliferationGO:007208940.020
protein acetylationGO:000647320.019
cell migrationGO:00164772370.019
mononuclear cell proliferationGO:003294310.019
regulation of multicellular organismal developmentGO:20000262230.019
regulation of blood pressureGO:000821710.019
cell substrate adhesionGO:003158940.019
single organism metabolic processGO:00447102170.019
production of molecular mediator of immune responseGO:000244020.019
neuron neuron synaptic transmissionGO:000727010.019
adult behaviorGO:003053420.019
internal peptidyl lysine acetylationGO:001839320.019
hepaticobiliary system developmentGO:0061008980.019
nuclear exportGO:005116810.019
regulation of circadian rhythmGO:004275240.019
actin filament polymerizationGO:003004120.019
organelle organizationGO:00069962270.019
regulation of carbohydrate metabolic processGO:000610940.019
phagocytosis engulfmentGO:000691110.019
regulation of developmental processGO:00507932470.019
regulation of cellular amino acid metabolic processGO:000652100.019
negative regulation of protein transportGO:005122430.019
regulation of bindingGO:005109830.019
liver developmentGO:0001889960.019
carbohydrate homeostasisGO:003350010.018
positive regulation of secretionGO:005104710.018
regulation of protein targetingGO:190353320.018
ventricular cardiac muscle tissue developmentGO:000322930.018
positive regulation of cellular processGO:00485222010.018
single organism organelle organizationGO:19025891990.018
somatic muscle developmentGO:000752540.018
positive regulation of secretion by cellGO:190353210.018
i kappab kinase nf kappab signalingGO:000724940.018
regulation of hormone secretionGO:004688320.018
organic acid metabolic processGO:0006082310.018
meiotic cell cycle processGO:190304630.018
guanosine containing compound metabolic processGO:190106840.018
negative regulation of protein kinase activityGO:000646940.018
cellular component disassemblyGO:002241110.018
compound eye developmentGO:004874920.018
determination of heart left right asymmetryGO:00613711170.018
regulation of metal ion transportGO:001095940.018
system processGO:00030081850.018
response to alkaloidGO:004327920.018
negative regulation of kinase activityGO:003367340.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
regulation of cellular carbohydrate metabolic processGO:001067540.018
cell motilityGO:00488702440.018
deathGO:00162651210.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
regulation of autophagyGO:001050630.017
heart morphogenesisGO:00030071560.017
ameboidal type cell migrationGO:00016671430.017
single organism transportGO:00447652060.017
retina development in camera type eyeGO:00600411460.017
carboxylic acid metabolic processGO:0019752220.017
negative regulation of cytoplasmic transportGO:190365020.017
camera type eye developmentGO:00430102220.017
negative regulation of catabolic processGO:000989530.017
ribonucleoside monophosphate catabolic processGO:000915840.017
post embryonic organ developmentGO:004856940.017
regulation of stem cell differentiationGO:200073640.017
cell part morphogenesisGO:00329902460.017
gtp catabolic processGO:000618420.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
sleepGO:003043110.017
lipid catabolic processGO:001604240.017
locomotor rhythmGO:004547530.017
cellular response to chemical stimulusGO:00708871570.017
regulation of reproductive processGO:200024140.017
regulation of response to biotic stimulusGO:000283120.017
regulation of cellular protein catabolic processGO:190336210.017
inositol lipid mediated signalingGO:004801720.017
mesenchyme developmentGO:00604851270.017
neuron developmentGO:00486662620.017
response to other organismGO:0051707970.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
phosphatidylinositol mediated signalingGO:004801520.017
positive regulation of immune effector processGO:000269930.017
membrane fusionGO:006102520.017
negative regulation of cytokine productionGO:000181810.017
positive regulation of map kinase activityGO:004340630.017
cellular response to oxygen levelsGO:007145310.017
embryonic skeletal joint developmentGO:007249830.016
cognitionGO:005089010.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
skeletal system morphogenesisGO:00487051020.016
regulation of muscle contractionGO:000693730.016
negative regulation of macromolecule metabolic processGO:0010605760.016
nucleoside monophosphate catabolic processGO:000912540.016
b cell activationGO:004211320.016
startle responseGO:000196440.016
regulation of synaptic plasticityGO:004816710.016
regulation of neural precursor cell proliferationGO:200017730.016
glucose homeostasisGO:004259310.016
regulation of sodium ion transportGO:000202820.016
ear developmentGO:00435831270.016
energy reserve metabolic processGO:000611220.016
protein localization to plasma membraneGO:007265910.016
response to topologically incorrect proteinGO:003596620.016
regulation of reactive oxygen species metabolic processGO:200037720.016
regulation of glial cell differentiationGO:004568540.016
regulation of protein ubiquitinationGO:003139630.016
cell matrix adhesionGO:000716040.016
response to external biotic stimulusGO:0043207970.016
multi organism cellular processGO:004476420.016
cell morphogenesis involved in differentiationGO:00009041950.016
positive regulation of inflammatory responseGO:005072910.016
protein acylationGO:004354330.015
cellular response to radiationGO:007147840.015
zymogen activationGO:003163830.015
smooth muscle contractionGO:000693920.015
embryonic skeletal system morphogenesisGO:0048704930.015
epithelial tube morphogenesisGO:00605621480.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
eye morphogenesisGO:00485921440.015
negative regulation of reproductive processGO:200024230.015
regulation of synapse organizationGO:005080730.015
myeloid cell differentiationGO:0030099860.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
atp catabolic processGO:000620040.015
lipid homeostasisGO:005508830.015
purine nucleoside monophosphate catabolic processGO:000912840.015
small molecule metabolic processGO:0044281770.015
single organism membrane fusionGO:004480120.015
protein secretionGO:000930610.015
sensory organ morphogenesisGO:00905962000.015
embryonic heart tube developmentGO:00350501330.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
organonitrogen compound metabolic processGO:1901564740.015
regulation of mrna processingGO:005068430.015
protein dephosphorylationGO:000647030.015
positive regulation of cellular amine metabolic processGO:003324000.015
localization of cellGO:00516742440.015
response to corticosteroidGO:003196010.015
positive regulation of metabolic processGO:00098931080.015
sensory system developmentGO:0048880760.015
regulation of protein polymerizationGO:003227120.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
embryonic cranial skeleton morphogenesisGO:0048701900.014
angiogenesisGO:00015251580.014
regulation of nucleotide catabolic processGO:003081120.014
adherens junction organizationGO:003433240.014
negative regulation of defense responseGO:003134820.014
cell cycle g1 s phase transitionGO:004484310.014
organelle assemblyGO:00709251100.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
guanosine containing compound catabolic processGO:190106920.014
cellular response to molecule of bacterial originGO:007121930.014
regulation of epithelial cell proliferationGO:005067830.014
regulation of wound healingGO:006104120.014
cellular protein metabolic processGO:00442671290.014
hindbrain developmentGO:0030902910.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
negative regulation of synapse assemblyGO:005196420.014
neurotransmitter transportGO:000683620.014
positive regulation of myeloid cell differentiationGO:004563920.014
negative regulation of map kinase activityGO:004340720.014
rna transportGO:005065820.014
exocytosisGO:000688710.014
gtp metabolic processGO:004603940.014
peptide metabolic processGO:000651810.014
positive regulation of cytoskeleton organizationGO:005149530.014
negative regulation of epithelial cell proliferationGO:005068010.014
g1 s transition of mitotic cell cycleGO:000008210.014
protein complex disassemblyGO:004324110.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
cell deathGO:00082191210.014
intracellular signal transductionGO:0035556850.014
protein polymerizationGO:005125840.014
regulation of nucleoside metabolic processGO:000911820.014
inner ear developmentGO:00488391260.014
positive regulation of protein complex assemblyGO:003133420.014
primary neural tube formationGO:001402010.014
regulation of ion transmembrane transporter activityGO:003241220.014
somatic stem cell maintenanceGO:003501910.014
embryonic heart tube morphogenesisGO:00031431080.014
synaptic growth at neuromuscular junctionGO:005112420.014
regulation of purine nucleotide catabolic processGO:003312120.014
regionalizationGO:00030022740.014
transmembrane transportGO:00550851200.013
immunoglobulin mediated immune responseGO:001606430.013
small molecule catabolic processGO:004428230.013
regulation of dna templated transcription in response to stressGO:004362000.013
negative regulation of chromosome organizationGO:200125110.013
negative regulation of intracellular transportGO:003238730.013
nucleic acid transportGO:005065720.013
negative regulation of protein localization to nucleusGO:190018120.013
dna templated transcription elongationGO:000635430.013
organism emergence from protective structureGO:007168440.013
regulation of tube sizeGO:003515020.013
regulation of neuronal synaptic plasticityGO:004816810.013
heart loopingGO:0001947940.013
neuromast developmentGO:0048884460.013
erk1 and erk2 cascadeGO:007037140.013
cellular response to hypoxiaGO:007145610.013
glial cell migrationGO:000834730.013
interspecies interaction between organismsGO:004441940.013
regulation of dendrite developmentGO:005077330.013
regulation of transporter activityGO:003240920.013
negative regulation of protein complex assemblyGO:003133310.013
positive regulation of nucleoside metabolic processGO:004597910.013
carbohydrate biosynthetic processGO:001605110.013
b cell mediated immunityGO:001972430.013
response to ketoneGO:190165410.013
rna 3 end processingGO:003112320.013
negative regulation of protein import into nucleusGO:004230820.013
extrinsic apoptotic signaling pathwayGO:009719130.013
organelle fusionGO:004828430.013
regulation of myotube differentiationGO:001083020.013
apoptotic processGO:00069151160.013
toll like receptor signaling pathwayGO:000222440.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
positive regulation of dna metabolic processGO:005105410.013
homeostatic processGO:00425921420.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
multi organism processGO:00517041340.013
regulation of dna recombinationGO:000001820.013
response to glucocorticoidGO:005138410.013
signal transduction in absence of ligandGO:003803410.013
regulation of blood vessel sizeGO:005088020.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
negative regulation of cellular catabolic processGO:003133030.013
regulation of localizationGO:00328791040.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
positive regulation of nucleotide catabolic processGO:003081310.013
cellular response to biotic stimulusGO:007121630.013
skeletal system developmentGO:00015011810.013
macromolecular complex disassemblyGO:003298410.013
lateral inhibitionGO:004633110.013
regulation of transmembrane transporter activityGO:002289820.013
protein stabilizationGO:005082120.013
negative regulation of dna metabolic processGO:005105340.013
synaptic vesicle localizationGO:009747910.012
microtubule organizing center organizationGO:003102310.012
response to biotic stimulusGO:0009607970.012
spermatid developmentGO:000728620.012
negative regulation of mapk cascadeGO:004340940.012
programmed cell deathGO:00125011190.012
regulation of erk1 and erk2 cascadeGO:007037240.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of cell substrate adhesionGO:001081010.012
macroautophagyGO:001623610.012
response to woundingGO:00096111160.012
cellular response to light stimulusGO:007148240.012
long chain fatty acid metabolic processGO:000167610.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
viral processGO:001603210.012
axon guidanceGO:0007411860.012
regulation of meiotic cell cycleGO:005144510.012
cellular amino acid metabolic processGO:000652070.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
neurotransmitter secretionGO:000726920.012
positive regulation of protein polymerizationGO:003227320.012
photoreceptor cell differentiationGO:0046530550.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
regulation of cell matrix adhesionGO:000195210.012
circadian sleep wake cycle sleepGO:005080210.012
photoreceptor cell fate commitmentGO:004655210.012
positive regulation of biosynthetic processGO:0009891680.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
anterior posterior pattern specificationGO:00099521520.012
cell cycle arrestGO:000705010.012
neuron projection developmentGO:00311751800.012
amino acid transportGO:000686520.012
regulation of protein bindingGO:004339330.012
cell projection organizationGO:00300302840.012
negative regulation of cell communicationGO:0010648960.012
pancreas developmentGO:0031016840.012
negative regulation of intracellular protein transportGO:009031730.012
histone h3 k4 methylationGO:005156820.012
centrosome cycleGO:000709810.012
regulation of dna replicationGO:000627530.012
wound healingGO:0042060900.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
peptidyl serine phosphorylationGO:001810510.012
mesoderm developmentGO:0007498880.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
positive regulation of epithelial cell differentiationGO:003085820.012
response to unfolded proteinGO:000698620.011
astrocyte differentiationGO:004870810.011
negative regulation of metabolic processGO:0009892860.011
mitotic dna integrity checkpointGO:004477440.011
epithelial cell differentiationGO:00308551160.011
lateral line system developmentGO:0048925760.011
tube closureGO:006060610.011
regenerationGO:0031099910.011
muscle structure developmentGO:00610611960.011
macromolecule modificationGO:00434121110.011
negative regulation of response to stimulusGO:00485851040.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
fertilizationGO:000956630.011
cytoskeleton dependent cytokinesisGO:006164030.011
photoreceptor cell developmentGO:0042461400.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
cellular response to decreased oxygen levelsGO:003629410.011
cellular response to reactive oxygen speciesGO:003461420.011
regulation of organ growthGO:004662030.011
regulation of cellular component organizationGO:0051128860.011
spindle assemblyGO:005122520.011
single organism biosynthetic processGO:0044711710.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
somatic cell dna recombinationGO:001644410.011
negative regulation of signal transductionGO:0009968940.011
protein heterooligomerizationGO:005129110.011
regulation of circadian sleep wake cycleGO:004274910.011
positive regulation of cellular metabolic processGO:0031325940.011

dot1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.050
musculoskeletal system diseaseDOID:1700.027
nervous system diseaseDOID:86300.024
cardiovascular system diseaseDOID:128700.017
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
disease of metabolismDOID:001466700.015
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011