Danio rerio

0 known processes

eif2ak3

eukaryotic translation initiation factor 2-alpha kinase 3

(Aliases: zgc:152949,MGC152949,PEK)

eif2ak3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.333
cell part morphogenesisGO:00329902460.214
neuron differentiationGO:00301823530.187
response to abiotic stimulusGO:00096281220.159
cell projection organizationGO:00300302840.145
camera type eye morphogenesisGO:00485931080.143
retina development in camera type eyeGO:00600411460.140
generation of neuronsGO:00486993850.139
head developmentGO:00603223030.134
brain developmentGO:00074202930.134
striated muscle cell developmentGO:00550021080.128
eye morphogenesisGO:00485921440.127
embryonic organ developmentGO:00485683810.121
neuron developmentGO:00486662620.120
cellular component movementGO:00069283350.111
cell morphogenesis involved in neuron differentiationGO:00486671630.105
regulation of multicellular organismal developmentGO:20000262230.101
response to stressGO:00069502630.094
regulation of multicellular organismal processGO:00512392770.090
renal system developmentGO:0072001940.090
cellular biosynthetic processGO:00442492860.088
nucleobase containing compound metabolic processGO:00061392740.088
heterocycle metabolic processGO:00464832900.081
neuron projection morphogenesisGO:00488121610.080
regulation of signalingGO:00230512350.080
neuron projection developmentGO:00311751800.074
blood vessel morphogenesisGO:00485142160.072
modification dependent protein catabolic processGO:001994130.072
regulation of nitrogen compound metabolic processGO:00511712510.071
sensory organ morphogenesisGO:00905962000.071
regulation of neuron differentiationGO:0045664560.070
retina morphogenesis in camera type eyeGO:0060042790.069
muscle structure developmentGO:00610611960.067
system processGO:00030081850.066
muscle cell differentiationGO:00426921390.064
axonogenesisGO:00074091520.063
cellular component assemblyGO:00226071700.063
regulation of metabolic processGO:00192223590.063
larval developmentGO:000216420.062
regulation of developmental processGO:00507932470.062
positive regulation of cellular processGO:00485222010.061
gene expressionGO:00104672520.061
organic substance biosynthetic processGO:19015762890.061
astrocyte differentiationGO:004870810.059
ubiquitin dependent protein catabolic processGO:000651130.059
central nervous system developmentGO:00074173870.059
hindbrain developmentGO:0030902910.057
developmental growthGO:00485891660.057
eye developmentGO:00016542770.055
negative regulation of protein phosphorylationGO:000193340.054
cellular component morphogenesisGO:00329893360.054
urogenital system developmentGO:0001655970.053
regulation of locomotionGO:0040012550.053
cellular nitrogen compound metabolic processGO:00346412900.053
homeostatic processGO:00425921420.052
cell morphogenesisGO:00009022890.050
gland developmentGO:00487321430.050
response to chemicalGO:00422213200.050
regulation of organ growthGO:004662030.049
nucleic acid metabolic processGO:00903042440.048
cilium organizationGO:0044782710.047
regulation of synapse organizationGO:005080730.047
spermatid differentiationGO:004851520.046
dna metabolic processGO:0006259270.046
organic cyclic compound metabolic processGO:19013603010.045
regulation of establishment of protein localizationGO:007020140.045
negative regulation of cellular processGO:00485232830.044
cellular macromolecule metabolic processGO:00442603910.043
cell projection morphogenesisGO:00488582440.043
cellular aromatic compound metabolic processGO:00067252950.043
cellular response to external stimulusGO:007149620.043
regenerationGO:0031099910.042
signal transductionGO:00071654550.042
camera type eye developmentGO:00430102220.041
cellular component biogenesisGO:00440851780.041
macromolecular complex subunit organizationGO:0043933740.041
cell morphogenesis involved in differentiationGO:00009041950.040
positive regulation of transportGO:005105020.040
modification dependent macromolecule catabolic processGO:004363230.040
organelle assemblyGO:00709251100.040
regulation of biosynthetic processGO:00098892500.038
cell motilityGO:00488702440.038
pancreas developmentGO:0031016840.038
single organism organelle organizationGO:19025891990.038
regulation of protein transportGO:005122330.038
regulation of biological qualityGO:00650082630.037
agingGO:000756820.037
nucleocytoplasmic transportGO:000691340.037
kidney developmentGO:0001822920.037
regulation of multicellular organism growthGO:004001440.036
female sex differentiationGO:004666040.036
epithelial cell differentiationGO:00308551160.036
chemotaxisGO:00069351040.035
circadian sleep wake cycle processGO:002241020.035
striated muscle tissue developmentGO:00147061100.035
centrosome organizationGO:005129710.035
cell migrationGO:00164772370.034
multicellular organism growthGO:003526440.033
endodermal cell fate determinationGO:000749320.033
positive regulation of macromolecule biosynthetic processGO:0010557590.033
response to carbohydrateGO:000974330.033
regulation of neurogenesisGO:0050767870.032
hemopoiesisGO:00300971830.032
cellular protein modification processGO:00064641000.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
cellular localizationGO:0051641970.031
negative regulation of protein transportGO:005122430.031
lipid oxidationGO:003444010.031
regulation of defense response to virus by hostGO:005069110.030
cilium morphogenesisGO:0060271850.030
axon developmentGO:00615641660.030
organelle organizationGO:00069962270.030
angiogenesisGO:00015251580.030
blood vessel developmentGO:00015682460.029
pigmentationGO:0043473850.029
axon guidanceGO:0007411860.029
hepaticobiliary system developmentGO:0061008980.029
negative regulation of biological processGO:00485193040.029
nitrogen compound metabolic processGO:00068073190.029
single organism transportGO:00447652060.029
microtubule organizing center organizationGO:003102310.028
striated muscle cell differentiationGO:00511461290.028
heart developmentGO:00075073130.028
cellular response to extracellular stimulusGO:003166820.027
muscle tissue developmentGO:00605371100.027
transcription dna templatedGO:00063511810.027
heart morphogenesisGO:00030071560.027
response to nutrientGO:000758430.026
regulation of systemic arterial blood pressureGO:000307310.026
regulation of cytokine productionGO:000181730.026
protein heterooligomerizationGO:005129110.026
embryonic camera type eye developmentGO:0031076290.026
neurotransmitter transportGO:000683620.026
cellular protein catabolic processGO:004425740.026
response to decreased oxygen levelsGO:0036293250.026
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.026
regulation of protein localization to nucleusGO:190018020.026
positive regulation of dna metabolic processGO:005105410.025
growthGO:00400071740.025
regulation of cellular protein metabolic processGO:0032268520.025
embryonic retina morphogenesis in camera type eyeGO:0060059220.025
regulation of reactive oxygen species metabolic processGO:200037720.025
establishment of protein localization to organelleGO:007259440.024
neuron projection guidanceGO:0097485860.024
nucleobase containing compound biosynthetic processGO:00346542050.024
response to external stimulusGO:00096052640.024
maintenance of locationGO:005123540.024
photoreceptor cell differentiationGO:0046530550.024
cellular response to nutrient levelsGO:003166920.024
cellular macromolecule biosynthetic processGO:00346452240.023
proteasomal protein catabolic processGO:001049820.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
regulation of circadian rhythmGO:004275240.023
nuclear transportGO:005116940.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
cytokinesisGO:000091030.023
tissue regenerationGO:0042246740.023
regulation of cell developmentGO:00602841000.022
lipid catabolic processGO:001604240.022
establishment of localizationGO:00512342440.022
circadian sleep wake cycleGO:004274520.022
morphogenesis of an epitheliumGO:00020093330.022
localization of cellGO:00516742440.022
p38mapk cascadeGO:003806610.022
regulation of phosphate metabolic processGO:0019220430.022
response to topologically incorrect proteinGO:003596620.022
microtubule based processGO:0007017600.021
positive regulation of macromolecule metabolic processGO:0010604930.021
cellular response to starvationGO:000926710.021
single organism localizationGO:19025782250.021
negative regulation of signalingGO:0023057960.021
embryonic eye morphogenesisGO:0048048300.021
cellular response to oxygen levelsGO:007145310.020
patterning of blood vesselsGO:0001569150.020
response to glucoseGO:000974930.020
protein importGO:001703830.020
negative regulation of oocyte developmentGO:006028320.020
protein localization to nucleusGO:003450430.020
regulation of rna metabolic processGO:00512522240.020
skeletal system developmentGO:00015011810.020
biosynthetic processGO:00090582940.019
regulation of mrna processingGO:005068430.019
sexual reproductionGO:0019953360.019
muscle organ developmentGO:00075171010.019
protein import into nucleusGO:000660630.019
regulation of nervous system developmentGO:0051960900.019
regulation of response to oxidative stressGO:190288220.019
rna biosynthetic processGO:00327741810.019
transmembrane transportGO:00550851200.019
positive regulation of cellular catabolic processGO:003133130.018
chemical homeostasisGO:0048878490.018
small molecule metabolic processGO:0044281770.018
regulation of protein metabolic processGO:0051246560.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
protein metabolic processGO:00195381830.018
positive regulation of biological processGO:00485182530.018
aorta developmentGO:003590440.018
immune system developmentGO:00025201910.018
cellular response to stressGO:0033554620.018
neural nucleus developmentGO:0048857150.018
negative regulation of ras protein signal transductionGO:004658010.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
negative regulation of small gtpase mediated signal transductionGO:005105810.018
regulation of cellular component movementGO:0051270550.018
regulation of dna replicationGO:000627530.018
peptidyl serine modificationGO:001820920.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
cellular protein metabolic processGO:00442671290.017
locomotionGO:00400113130.017
innervationGO:006038430.017
regulation of circadian sleep wake cycleGO:004274910.017
liver developmentGO:0001889960.017
positive regulation of metabolic processGO:00098931080.017
cognitionGO:005089010.016
adult behaviorGO:003053420.016
gastrulation with mouth forming secondGO:0001702440.016
multi organism processGO:00517041340.016
positive regulation of cellular metabolic processGO:0031325940.016
transportGO:00068102200.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
apoptotic processGO:00069151160.016
regulation of protein targetingGO:190353320.016
sensory organ developmentGO:00074233930.016
muscle cell developmentGO:00550011150.015
developmental pigmentationGO:0048066480.015
regulation of nucleocytoplasmic transportGO:004682220.015
macromolecular complex assemblyGO:0065003350.015
regulation of cellular amine metabolic processGO:003323800.015
macromolecule modificationGO:00434121110.015
embryonic organ morphogenesisGO:00485622740.015
connective tissue developmentGO:0061448990.015
tube morphogenesisGO:00352393490.015
cellular response to decreased oxygen levelsGO:003629410.015
camera type eye photoreceptor cell differentiationGO:0060219190.015
regulation of molecular functionGO:0065009700.015
positive regulation of jnk cascadeGO:004633030.015
dorsal motor nucleus of vagus nerve developmentGO:002174440.015
immune system processGO:00023762410.015
programmed cell deathGO:00125011190.015
regulation of developmental growthGO:0048638380.015
cellular response to biotic stimulusGO:007121630.015
regulation of cellular response to oxidative stressGO:190040720.015
regulation of cytoplasmic transportGO:190364940.014
positive regulation of cell cycleGO:004578730.014
regulation of anatomical structure morphogenesisGO:00226031300.014
regulation of protein ubiquitinationGO:003139630.014
heterocycle biosynthetic processGO:00181302150.014
positive regulation of cellular component biogenesisGO:004408930.014
macromolecule localizationGO:0033036540.014
regulation of cell growthGO:0001558290.014
embryo development ending in birth or egg hatchingGO:00097922710.014
positive regulation of catabolic processGO:000989640.014
b cell activationGO:004211320.014
reproductive processGO:0022414400.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
regulation of dendrite morphogenesisGO:004881430.014
nephron morphogenesisGO:007202820.014
peripheral nervous system developmentGO:0007422550.014
cellular response to hypoxiaGO:007145610.014
regulation of cell differentiationGO:00455951420.013
myotome developmentGO:006105510.013
cartilage developmentGO:0051216960.013
single organism nuclear importGO:190259330.013
negative regulation of protein kinase activityGO:000646940.013
anterior posterior pattern specificationGO:00099521520.013
aorta morphogenesisGO:003590930.013
cellular response to radiationGO:007147840.013
positive regulation of neuron deathGO:190121610.013
blood circulationGO:0008015870.013
cellular response to growth factor stimulusGO:0071363390.013
cell cycleGO:0007049930.013
pronephros developmentGO:0048793690.013
response to hypoxiaGO:0001666250.013
regulation of response to biotic stimulusGO:000283120.013
carbohydrate homeostasisGO:003350010.013
negative regulation of cell communicationGO:0010648960.013
g1 s transition of mitotic cell cycleGO:000008210.013
negative regulation of cytoplasmic transportGO:190365020.013
sympathetic ganglion developmentGO:006154920.013
hypothalamus cell differentiationGO:002197940.013
mesodermal cell migrationGO:0008078120.012
negative regulation of intracellular protein transportGO:009031730.012
regulation of cellular component organizationGO:0051128860.012
smooth muscle tissue developmentGO:004874510.012
regulation of metal ion transportGO:001095940.012
response to woundingGO:00096111160.012
lymphatic endothelial cell fate commitmentGO:006083810.012
regulation of signal transductionGO:00099662250.012
regulation of cellular biosynthetic processGO:00313262450.012
embryonic heart tube developmentGO:00350501330.012
ion transportGO:00068111140.012
meiotic nuclear divisionGO:000712640.012
epithelial tube morphogenesisGO:00605621480.012
regulation of dendrite developmentGO:005077330.012
negative regulation of gene expressionGO:0010629650.012
cellular response to molecule of bacterial originGO:007121930.012
neuroblast differentiationGO:001401610.012
proteolysisGO:0006508380.012
single organism reproductive processGO:0044702400.012
neuromuscular synaptic transmissionGO:000727420.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
regulation of tube sizeGO:003515020.012
metencephalon developmentGO:0022037270.012
regulation of macromolecule metabolic processGO:00602553170.011
regulation of response to stimulusGO:00485832690.011
negative regulation of developmental processGO:0051093650.011
organonitrogen compound metabolic processGO:1901564740.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
regulation of stem cell differentiationGO:200073640.011
negative regulation of kinase activityGO:003367340.011
positive regulation of gene expressionGO:0010628710.011
thrombocyte differentiationGO:000257440.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
fin regenerationGO:0031101510.011
regulation of purine nucleotide catabolic processGO:003312120.011
protein modification processGO:00362111000.011
protein secretionGO:000930610.011
digestive tract mesoderm developmentGO:000750210.011
positive regulation of protein complex assemblyGO:003133420.011
cellular response to chemical stimulusGO:00708871570.011
lymphatic endothelial cell differentiationGO:006083610.011
regulation of cell motilityGO:2000145460.011
transcription from rna polymerase ii promoterGO:0006366800.011
digestive system developmentGO:00551232890.011
taxisGO:00423301090.011
rna stabilizationGO:004348940.011
regulation of cell deathGO:00109411030.011
response to hexoseGO:000974630.011
cellular lipid catabolic processGO:004424230.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
hormone secretionGO:004687920.011
cardioblast migration to the midline involved in heart field formationGO:006097570.011
regulation of fatty acid metabolic processGO:001921710.011
behaviorGO:0007610740.011
regulation of growthGO:0040008420.011
rna metabolic processGO:00160702190.011
regulation of cell activationGO:005086510.011
guanosine containing compound metabolic processGO:190106840.011
protein modification by small protein removalGO:007064610.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
organic cyclic compound biosynthetic processGO:19013622230.011
adherens junction organizationGO:003433240.011
regulation of transcription dna templatedGO:00063552130.011
spermatid developmentGO:000728620.011
regulation of microtubule cytoskeleton organizationGO:007050730.010
cytoskeleton organizationGO:0007010960.010
limbic system developmentGO:0021761160.010
establishment of localization in cellGO:0051649770.010
response to uvGO:000941130.010
regulation of catalytic activityGO:0050790550.010
mechanosensory behaviorGO:000763820.010
regulation of cellular ketone metabolic processGO:001056570.010
guanosine containing compound catabolic processGO:190106920.010
endoplasmic reticulum unfolded protein responseGO:003096820.010
b cell proliferationGO:004210010.010
rna localizationGO:000640340.010
regulation of protein phosphorylationGO:0001932180.010
nucleobase containing small molecule metabolic processGO:0055086320.010
response to corticosteroidGO:003196010.010
development of primary female sexual characteristicsGO:004654540.010
neural retina developmentGO:0003407490.010
protein homooligomerizationGO:005126030.010

eif2ak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.086
disease of metabolismDOID:001466700.041
cardiovascular system diseaseDOID:128700.027
inherited metabolic disorderDOID:65500.015
musculoskeletal system diseaseDOID:1700.010
muscle tissue diseaseDOID:6600.010
muscular diseaseDOID:008000000.010
immune system diseaseDOID:291400.010
hematopoietic system diseaseDOID:7400.010