Danio rerio

31 known processes

crb3a

crumbs homolog 3a

crb3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apical protein localizationGO:004517660.594
dorsal motor nucleus of vagus nerve developmentGO:002174440.551
medulla oblongata developmentGO:002155040.516
eye developmentGO:00016542770.362
brain developmentGO:00074202930.250
cilium assemblyGO:0042384580.237
cilium morphogenesisGO:0060271850.226
eye photoreceptor cell developmentGO:0042462300.214
asymmetric protein localizationGO:000810560.209
regulation of cell communicationGO:00106462320.203
detection of visible lightGO:0009584120.196
cell surface receptor signaling pathwayGO:00071663250.191
cilium organizationGO:0044782710.184
signal transductionGO:00071654550.178
wnt signaling pathwayGO:0016055800.175
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.162
renal system developmentGO:0072001940.146
eye morphogenesisGO:00485921440.139
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.138
morphogenesis of an epitheliumGO:00020093330.137
retina development in camera type eyeGO:00600411460.134
single organism organelle organizationGO:19025891990.133
neuron developmentGO:00486662620.132
cellular response to radiationGO:007147840.131
visual perceptionGO:0007601170.129
regulation of signalingGO:00230512350.126
negative regulation of signalingGO:0023057960.125
camera type eye developmentGO:00430102220.124
glomerulus developmentGO:0032835270.116
swim bladder developmentGO:0048794190.112
photoreceptor cell developmentGO:0042461400.110
response to drugGO:004249330.110
regulation of signal transductionGO:00099662250.109
sensory organ developmentGO:00074233930.108
cell projection assemblyGO:0030031640.107
negative regulation of biological processGO:00485193040.107
negative regulation of cell communicationGO:0010648960.105
pronephros developmentGO:0048793690.105
cellular macromolecule metabolic processGO:00442603910.105
regulation of canonical wnt signaling pathwayGO:0060828340.100
digestive tract morphogenesisGO:00485462310.099
neurological system processGO:0050877620.099
nephron developmentGO:0072006310.096
photoreceptor cell differentiationGO:0046530550.096
head developmentGO:00603223030.095
renal system processGO:0003014140.094
cell morphogenesisGO:00009022890.093
phototransductionGO:000760220.093
establishment or maintenance of apical basal cell polarityGO:0035088120.092
g protein coupled receptor signaling pathwayGO:0007186740.087
cellular component assembly involved in morphogenesisGO:00109271070.086
cellular component biogenesisGO:00440851780.085
cell projection organizationGO:00300302840.083
single organismal cell cell adhesionGO:0016337290.081
system processGO:00030081850.075
organelle assemblyGO:00709251100.072
protein metabolic processGO:00195381830.071
rhodopsin mediated signaling pathwayGO:001605610.067
agingGO:000756820.065
urogenital system developmentGO:0001655970.064
canonical wnt signaling pathwayGO:0060070480.061
organelle organizationGO:00069962270.060
cellular response to light stimulusGO:007148240.057
central nervous system developmentGO:00074173870.057
neuron differentiationGO:00301823530.057
negative regulation of signal transductionGO:0009968940.056
digestive system developmentGO:00551232890.056
light induced release of internally sequestered calcium ionGO:000837710.053
maintenance of locationGO:005123540.053
negative regulation of cellular processGO:00485232830.053
organic anion transportGO:0015711150.052
renal filtrationGO:0097205100.051
cell projection morphogenesisGO:00488582440.051
retina morphogenesis in camera type eyeGO:0060042790.050
regulation of response to stimulusGO:00485832690.050
cellular component morphogenesisGO:00329893360.050
negative regulation of response to stimulusGO:00485851040.049
generation of neuronsGO:00486993850.049
sensory organ morphogenesisGO:00905962000.046
cell part morphogenesisGO:00329902460.045
regulation of wnt signaling pathwayGO:0030111530.045
regulation of stem cell differentiationGO:200073640.043
regulation of multicellular organism growthGO:004001440.042
regulation of biological qualityGO:00650082630.042
muscle structure developmentGO:00610611960.042
heterocycle biosynthetic processGO:00181302150.041
proteasomal protein catabolic processGO:001049820.041
cellular response to extracellular stimulusGO:003166820.040
establishment of localizationGO:00512342440.040
cell cell adhesionGO:009860960.040
locomotionGO:00400113130.040
kidney developmentGO:0001822920.038
phototransduction visible lightGO:000760320.037
notch signaling pathwayGO:0007219350.037
striated muscle cell differentiationGO:00511461290.037
multicellular organismal homeostasisGO:0048871290.037
sensory perception of light stimulusGO:0050953190.036
smoothened signaling pathwayGO:0007224300.036
glomerular filtrationGO:000309460.035
multicellular organism growthGO:003526440.035
biological adhesionGO:0022610400.035
cellular component assemblyGO:00226071700.035
cellular response to external stimulusGO:007149620.035
cellular response to nutrient levelsGO:003166920.034
regulation of macromolecule metabolic processGO:00602553170.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
muscle cell differentiationGO:00426921390.034
regulation of metabolic processGO:00192223590.034
regulation of bindingGO:005109830.033
cellular component disassemblyGO:002241110.033
liver developmentGO:0001889960.032
phosphorus metabolic processGO:00067931090.032
positive regulation of cellular processGO:00485222010.032
heterocycle metabolic processGO:00464832900.032
ion transportGO:00068111140.032
cognitionGO:005089010.032
cell motilityGO:00488702440.031
single organism transportGO:00447652060.031
regulation of muscle contractionGO:000693730.031
positive regulation of cellular component biogenesisGO:004408930.031
muscle cell developmentGO:00550011150.031
cellular component movementGO:00069283350.030
proteolysis involved in cellular protein catabolic processGO:005160330.030
embryonic heart tube developmentGO:00350501330.030
digestive tract developmentGO:00485652650.030
detection of abiotic stimulusGO:0009582240.030
negative regulation of wnt signaling pathwayGO:0030178300.029
eye photoreceptor cell differentiationGO:0001754450.029
neurotransmitter secretionGO:000726920.029
regulation of establishment of protein localizationGO:007020140.029
regulation of carbohydrate metabolic processGO:000610940.028
nucleobase containing compound metabolic processGO:00061392740.028
aromatic compound biosynthetic processGO:00194382170.028
determination of bilateral symmetryGO:00098552040.027
regulation of primary metabolic processGO:00800903110.027
macromolecule modificationGO:00434121110.027
response to abiotic stimulusGO:00096281220.027
camera type eye morphogenesisGO:00485931080.026
regulation of response to nutrient levelsGO:003210710.026
cell migrationGO:00164772370.026
regulation of molecular functionGO:0065009700.026
cellular nitrogen compound metabolic processGO:00346412900.026
single organism metabolic processGO:00447102170.025
compound eye developmentGO:004874920.025
regulation of protein bindingGO:004339330.025
negative regulation of canonical wnt signaling pathwayGO:0090090210.025
cellular response to starvationGO:000926710.025
nitrogen compound metabolic processGO:00068073190.024
carbon dioxide transportGO:001567030.024
apoptotic processGO:00069151160.024
nucleocytoplasmic transportGO:000691340.024
ubiquitin dependent protein catabolic processGO:000651130.024
protein secretionGO:000930610.024
establishment of synaptic vesicle localizationGO:009748010.024
hormone transportGO:000991420.024
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.024
positive regulation of cell cycleGO:004578730.024
cellular aromatic compound metabolic processGO:00067252950.023
regulation of neurotransmitter transportGO:005158810.022
transportGO:00068102200.022
gland developmentGO:00487321430.022
actin polymerization or depolymerizationGO:000815420.022
response to external stimulusGO:00096052640.022
establishment or maintenance of cell polarityGO:0007163290.022
vasculature developmentGO:00019442780.022
immune system processGO:00023762410.022
cell substrate adherens junction assemblyGO:000704510.022
localization of cellGO:00516742440.022
regulation of cellular metabolic processGO:00313233200.022
cellular protein catabolic processGO:004425740.022
adult behaviorGO:003053420.021
regulation of hormone secretionGO:004688320.021
biosynthetic processGO:00090582940.021
synaptic vesicle localizationGO:009747910.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
neural nucleus developmentGO:0048857150.021
embryonic organ developmentGO:00485683810.021
regulation of cellular protein metabolic processGO:0032268520.021
gastrulationGO:00073692080.021
response to light stimulusGO:0009416460.021
positive regulation of catabolic processGO:000989640.021
response to inorganic substanceGO:0010035380.021
detection of stimulusGO:0051606290.021
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.021
protein polymerizationGO:005125840.021
photoreceptor cell outer segment organizationGO:003584590.021
adherens junction organizationGO:003433240.020
positive regulation of transportGO:005105020.020
programmed cell deathGO:00125011190.020
cellular response to molecule of bacterial originGO:007121930.020
neurotransmitter transportGO:000683620.020
regulation of protein complex assemblyGO:004325430.020
regulation of nitrogen compound metabolic processGO:00511712510.020
nuclear transportGO:005116940.020
protein import into nucleusGO:000660630.020
chemotaxisGO:00069351040.020
response to uvGO:000941130.020
response to monosaccharideGO:003428430.019
macromolecule localizationGO:0033036540.019
gene expressionGO:00104672520.019
response to chemicalGO:00422213200.019
protein importGO:001703830.019
organonitrogen compound metabolic processGO:1901564740.019
protein complex disassemblyGO:004324110.019
exocytosisGO:000688710.019
peptidyl serine phosphorylationGO:001810510.019
positive regulation of cellular catabolic processGO:003133130.019
positive regulation of epithelial cell migrationGO:001063420.018
amino acid transportGO:000686520.018
sequestering of calcium ionGO:005120830.018
negative regulation of protein phosphorylationGO:000193340.018
organic cyclic compound metabolic processGO:19013603010.018
regulation of cell activationGO:005086510.018
regulation of gene expressionGO:00104682650.018
positive regulation of secretion by cellGO:190353210.018
cell matrix adhesionGO:000716040.018
sequestering of metal ionGO:005123830.018
establishment of endothelial barrierGO:006102830.017
single organism nuclear importGO:190259330.017
positive regulation of protein complex assemblyGO:003133420.017
embryonic retina morphogenesis in camera type eyeGO:0060059220.017
regulation of protein transportGO:005122330.017
modification dependent macromolecule catabolic processGO:004363230.017
positive regulation of cell matrix adhesionGO:000195410.017
epithelial cell morphogenesisGO:000338220.017
nucleic acid metabolic processGO:00903042440.017
heart morphogenesisGO:00030071560.017
homeostasis of number of cells within a tissueGO:004887340.017
chordate embryonic developmentGO:00430092710.017
guanosine containing compound metabolic processGO:190106840.017
regulation of tube sizeGO:003515020.017
establishment of protein localization to organelleGO:007259440.017
single organism cell adhesionGO:0098602290.017
protein localization to plasma membraneGO:007265910.016
positive regulation of secretionGO:005104710.016
sensory perceptionGO:0007600390.016
establishment or maintenance of bipolar cell polarityGO:0061245120.016
positive regulation of biological processGO:00485182530.016
heart developmentGO:00075073130.016
determination of heart left right asymmetryGO:00613711170.016
cation transportGO:0006812810.016
guanosine containing compound catabolic processGO:190106920.016
cell substrate adhesionGO:003158940.016
response to hexoseGO:000974630.016
transmembrane transportGO:00550851200.016
determination of left right symmetryGO:00073681790.016
ion transmembrane transportGO:0034220910.016
myelination in peripheral nervous systemGO:002201140.016
rna metabolic processGO:00160702190.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
protein complex localizationGO:003150310.016
macromolecular complex subunit organizationGO:0043933740.016
hepaticobiliary system developmentGO:0061008980.016
regulation of localizationGO:00328791040.016
regulation of epithelial cell proliferationGO:005067830.016
positive regulation of cell communicationGO:0010647560.016
positive regulation of cell adhesionGO:004578510.016
hemopoiesisGO:00300971830.016
cell agingGO:000756920.016
nucleobase containing compound biosynthetic processGO:00346542050.016
protein localizationGO:0008104400.016
embryonic organ morphogenesisGO:00485622740.015
extrinsic apoptotic signaling pathwayGO:009719130.015
myeloid cell differentiationGO:0030099860.015
maintenance of epithelial cell apical basal polarityGO:004519950.015
cellular macromolecule biosynthetic processGO:00346452240.015
regulation of cellular amine metabolic processGO:003323800.015
gas transportGO:001566930.015
regulation of apoptotic processGO:0042981980.015
peptide transportGO:001583310.015
mononuclear cell proliferationGO:003294310.015
monoamine transportGO:001584410.015
regulation of blood vessel sizeGO:005088020.015
tissue homeostasisGO:0001894250.015
regulation of cellular amino acid metabolic processGO:000652100.015
cell adhesionGO:0007155400.015
nuclear importGO:005117030.015
response to topologically incorrect proteinGO:003596620.015
long chain fatty acid metabolic processGO:000167610.015
larval developmentGO:000216420.015
positive regulation of cell substrate adhesionGO:001081110.015
alpha amino acid metabolic processGO:190160530.015
organic substance biosynthetic processGO:19015762890.015
regulation of sequestering of calcium ionGO:005128240.015
synaptic vesicle transportGO:004848910.015
establishment of localization in cellGO:0051649770.015
angiogenesisGO:00015251580.015
cellular carbohydrate metabolic processGO:004426240.015
light absorptionGO:001603720.014
neural tube formationGO:0001841160.014
gtp catabolic processGO:000618420.014
regulation of protein complex disassemblyGO:004324410.014
polarized epithelial cell differentiationGO:003085940.014
carbohydrate homeostasisGO:003350010.014
locomotor rhythmGO:004547530.014
organic cyclic compound biosynthetic processGO:19013622230.014
amine metabolic processGO:000930820.014
macromolecular complex disassemblyGO:003298410.014
protein targeting to nucleusGO:004474430.014
positive regulation of cell divisionGO:005178120.014
regulation of sodium ion transportGO:000202820.014
blood circulationGO:0008015870.014
phagocytosisGO:000690930.014
regulation of cellular biosynthetic processGO:00313262450.014
histone h3 k4 methylationGO:005156820.014
immune system developmentGO:00025201910.014
neuronal stem cell maintenanceGO:009715020.013
muscle organ developmentGO:00075171010.013
cellular localizationGO:0051641970.013
protein localization to nucleusGO:003450430.013
rna biosynthetic processGO:00327741810.013
regulation of protein targetingGO:190353320.013
regulation of circadian rhythmGO:004275240.013
regulation of calcium ion transportGO:005192420.013
cellular response to organic substanceGO:00713101050.013
phosphorylationGO:0016310690.013
regulation of protein import into nucleusGO:004230620.013
embryonic skeletal system developmentGO:0048706970.013
circulatory system processGO:0003013870.013
entrainment of circadian clock by photoperiodGO:004315310.013
embryo development ending in birth or egg hatchingGO:00097922710.013
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
regulation of notch signaling pathwayGO:0008593160.013
hindbrain developmentGO:0030902910.013
regulation of cell deathGO:00109411030.013
response to transition metal nanoparticleGO:1990267280.013
cellular response to xenobiotic stimulusGO:0071466350.013
organelle fusionGO:004828430.013
tube morphogenesisGO:00352393490.013
regulation of autophagyGO:001050630.013
positive regulation of blood circulationGO:190352420.013
developmental growth involved in morphogenesisGO:0060560860.012
small molecule metabolic processGO:0044281770.012
rhythmic processGO:0048511210.012
negative regulation of cytokine productionGO:000181810.012
actin mediated cell contractionGO:007025210.012
negative regulation of cell deathGO:0060548600.012
regulation of metal ion transportGO:001095940.012
regulation of cell differentiationGO:00455951420.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
embryonic limb morphogenesisGO:003032620.012
smooth muscle contractionGO:000693920.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
regulation of circadian sleep wake cycle sleepGO:004518710.012
negative regulation of epithelial cell proliferationGO:005068010.012
response to radiationGO:0009314510.012
negative regulation of kinase activityGO:003367340.012
peptidyl serine modificationGO:001820920.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
skeletal system morphogenesisGO:00487051020.012
response to glucoseGO:000974930.012
regulation of membrane potentialGO:0042391230.012
actin filament based movementGO:003004810.012
circadian sleep wake cycle sleepGO:005080210.012
regulation of reproductive processGO:200024140.012
spermatid differentiationGO:004851520.012
neuroblast proliferationGO:000740520.012
negative regulation of mapk cascadeGO:004340940.012
response to light intensityGO:000964210.012
synaptic growth at neuromuscular junctionGO:005112420.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
macromolecule biosynthetic processGO:00090592270.012
hormone secretionGO:004687920.012
adherens junction assemblyGO:003433310.012
cellular protein complex disassemblyGO:004362410.012
circadian sleep wake cycleGO:004274520.012
cellular amino acid metabolic processGO:000652070.012
regulation of protein localization to nucleusGO:190018020.011
protein depolymerizationGO:005126110.011
signal transduction in absence of ligandGO:003803410.011
peptidyl threonine modificationGO:001821010.011
stem cell proliferationGO:007208940.011
autophagyGO:000691440.011
glial cell proliferationGO:001400940.011
positive regulation of wnt signaling pathwayGO:0030177130.011
regulation of nucleocytoplasmic transportGO:004682220.011
striated muscle cell developmentGO:00550021080.011
cell deathGO:00082191210.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
response to stressGO:00069502630.011
positive regulation of synapse assemblyGO:005196510.011
morphogenesis of an epithelial sheetGO:0002011490.011
regulation of synaptic plasticityGO:004816710.011
regulation of blood pressureGO:000821710.011
regulation of endothelial cell proliferationGO:000193610.011
cell substrate junction assemblyGO:000704420.011
regulation of myotube differentiationGO:001083020.011
actin filament polymerizationGO:003004120.011
positive regulation of cytokine productionGO:000181920.011
positive regulation of inflammatory responseGO:005072910.011
cellular biosynthetic processGO:00442492860.011
positive regulation of glucose transportGO:001082810.011
b cell activationGO:004211320.011
multicellular organismal signalingGO:0035637220.011
carboxylic acid metabolic processGO:0019752220.011
cellular response to biotic stimulusGO:007121630.011
chemosensory behaviorGO:000763510.011
establishment of blood brain barrierGO:006085620.011
muscle organ morphogenesisGO:004864480.011
negative regulation of protein kinase activityGO:000646940.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
production of molecular mediator of immune responseGO:000244020.011
response to alkaloidGO:004327920.011
cellular protein modification processGO:00064641000.011
regionalizationGO:00030022740.011
single organism biosynthetic processGO:0044711710.011
centrosome organizationGO:005129710.011
neuron neuron synaptic transmissionGO:000727010.011
positive regulation of metabolic processGO:00098931080.011
cell morphogenesis involved in differentiationGO:00009041950.011
modification dependent protein catabolic processGO:001994130.011
regulation of intracellular protein transportGO:003315730.010
inner ear developmentGO:00488391260.010
positive regulation of protein polymerizationGO:003227320.010
anatomical structure homeostasisGO:0060249360.010
nuclear migrationGO:000709730.010
negative regulation of notch signaling pathwayGO:004574660.010
skeletal system developmentGO:00015011810.010
regulation of protein polymerizationGO:003227120.010
multi organism cellular processGO:004476420.010
positive regulation of cell activationGO:005086710.010
lymphocyte proliferationGO:004665110.010
gtp metabolic processGO:004603940.010
regulation of cell migrationGO:0030334400.010
lipid catabolic processGO:001604240.010
regulation of biosynthetic processGO:00098892500.010
regulation of cellular ketone metabolic processGO:001056570.010
regulation of inflammatory responseGO:005072720.010
positive regulation of cellular metabolic processGO:0031325940.010
taxisGO:00423301090.010
regulation of neurotransmitter secretionGO:004692810.010
protein modification processGO:00362111000.010
transcription dna templatedGO:00063511810.010
behaviorGO:0007610740.010

crb3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.107
nervous system diseaseDOID:86300.044
sensory system diseaseDOID:005015500.020
eye and adnexa diseaseDOID:149200.020
eye diseaseDOID:561400.020
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
immune system diseaseDOID:291400.011
musculoskeletal system diseaseDOID:1700.010