Danio rerio

14 known processes

smyhc2

slow myosin heavy chain 2

(Aliases: zgc:171631)

smyhc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
striated muscle myosin thick filament assemblyGO:007168860.962
Zebrafish Worm Fly
myofibril assemblyGO:0030239480.946
Zebrafish Mouse Worm Fly
muscle cell developmentGO:00550011150.943
Zebrafish Mouse Worm Fly
organelle assemblyGO:00709251100.927
Zebrafish Mouse Worm Fly
ventricular cardiac muscle tissue morphogenesisGO:005501020.908
Human
somatic muscle developmentGO:000752540.907
Fly
purine nucleoside monophosphate catabolic processGO:000912840.885
Human Mouse Rat Fly
ribonucleoside monophosphate catabolic processGO:000915840.875
Human Mouse Rat Fly
skeletal muscle organ developmentGO:0060538780.871
Zebrafish
skeletal myofibril assemblyGO:001486670.867
Zebrafish Worm Fly
cytokinesisGO:000091030.856
Yeast
striated muscle cell developmentGO:00550021080.834
Zebrafish Mouse Worm Fly
myosin filament organizationGO:003103360.827
Zebrafish Worm Fly
multicellular organismal movementGO:005087980.811
post embryonic morphogenesisGO:000988640.801
skeletal muscle tissue developmentGO:0007519670.794
Zebrafish
skeletal muscle contractionGO:000300950.763
somitogenesisGO:0001756870.732
Zebrafish
muscle organ developmentGO:00075171010.698
Human Zebrafish Mouse Fly
musculoskeletal movementGO:005088180.690
larval developmentGO:000216420.685
Worm
atp catabolic processGO:000620040.685
Human Mouse Rat Fly
striated muscle cell differentiationGO:00511461290.681
Zebrafish Mouse Worm Fly
blood circulationGO:0008015870.669
Human Mouse
heterocycle metabolic processGO:00464832900.663
Human Mouse Rat Fly
striated muscle tissue developmentGO:00147061100.655
Human Zebrafish Mouse
ventricular cardiac muscle tissue developmentGO:000322930.635
Human
cardiac chamber developmentGO:0003205190.608
Human
cardiac muscle cell differentiationGO:0055007300.578
Mouse
voluntary skeletal muscle contractionGO:000301040.565
skeletal muscle myosin thick filament assemblyGO:003024150.553
Worm Fly
cytoskeleton dependent cytokinesisGO:006164030.551
Yeast
purine ribonucleoside monophosphate catabolic processGO:000916940.541
Human Mouse Rat Fly
inositol lipid mediated signalingGO:004801720.532
Worm
directional locomotionGO:003305810.518
skeletal muscle fiber developmentGO:0048741350.516
Zebrafish
heart developmentGO:00075073130.492
Human Mouse
cardiac muscle tissue morphogenesisGO:005500870.484
Human
myotube differentiationGO:0014902450.475
Zebrafish
regulation of nucleoside metabolic processGO:000911820.465
Mouse
cellular component assembly involved in morphogenesisGO:00109271070.450
Zebrafish Mouse Worm Fly
muscle contractionGO:0006936180.440
regulation of blood circulationGO:1903522320.433
Human Mouse
actin filament organizationGO:0007015150.432
Zebrafish Fly
actin filament based movementGO:003004810.413
Human Mouse
regulation of blood pressureGO:000821710.407
Mouse
striated muscle contractionGO:0006941120.396
actomyosin structure organizationGO:0031032530.393
Yeast Zebrafish Mouse Worm Fly
protein stabilizationGO:005082120.346
Fly
muscle structure developmentGO:00610611960.312
Human Zebrafish Mouse Worm Fly
single organism organelle organizationGO:19025891990.303
Yeast Zebrafish Mouse Worm Fly
circulatory system processGO:0003013870.299
Human Mouse
heart processGO:0003015710.298
Human Mouse
muscle cell differentiationGO:00426921390.293
Zebrafish Mouse Worm Fly
heart morphogenesisGO:00030071560.284
Human
heart contractionGO:0060047710.282
Human Mouse
somite developmentGO:0061053960.278
Zebrafish
nucleoside monophosphate catabolic processGO:000912540.274
Human Mouse Rat Fly
regulation of muscle contractionGO:000693730.273
skeletal muscle thin filament assemblyGO:003024040.265
Zebrafish
cardiac ventricle developmentGO:000323190.253
Human
organic cyclic compound metabolic processGO:19013603010.245
Human Mouse Rat Fly
locomotory behaviorGO:0007626340.242
Worm
regulation of nucleotide catabolic processGO:003081120.240
Mouse
segment specificationGO:0007379120.231
Zebrafish
multicellular organismal reproductive processGO:0048609350.225
Worm Fly
cellular component assemblyGO:00226071700.223
Yeast Zebrafish Mouse Worm Fly
muscle fiber developmentGO:0048747520.216
Zebrafish Mouse
regulation of purine nucleotide catabolic processGO:003312120.197
Mouse
muscle tissue developmentGO:00605371100.195
Human Zebrafish Mouse
purine ribonucleotide metabolic processGO:0009150270.181
Human Mouse Rat Fly
system processGO:00030081850.179
regulation of biological qualityGO:00650082630.175
Human Mouse Fly
neuron developmentGO:00486662620.173
Worm
muscle system processGO:0003012200.169
muscle organ morphogenesisGO:004864480.162
Human
regulation of hydrolase activityGO:0051336280.157
Mouse
actin mediated cell contractionGO:007025210.155
Human
chordate embryonic developmentGO:00430092710.154
Zebrafish Mouse
actin cytoskeleton organizationGO:0030036630.149
Yeast Zebrafish Mouse Worm Fly
nitrogen compound metabolic processGO:00068073190.147
Human Mouse Rat Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.145
Mouse
sarcomere organizationGO:0045214260.143
Mouse Fly
actin filament based processGO:0030029640.140
Human Yeast Zebrafish Mouse Worm Fly
cellular component biogenesisGO:00440851780.132
Yeast Zebrafish Mouse Worm Fly
cardiac muscle tissue developmentGO:0048738480.122
Human Mouse
cardiac cell developmentGO:0055006210.118
Mouse
axonal fasciculationGO:0007413110.113
Worm
cellular biosynthetic processGO:00442492860.107
Mouse
multi organism processGO:00517041340.105
Worm Fly
twitch skeletal muscle contractionGO:001472140.105
cellular component morphogenesisGO:00329893360.105
Zebrafish Mouse Worm Fly
cell projection morphogenesisGO:00488582440.103
cardiac muscle cell developmentGO:0055013200.102
Mouse
organelle organizationGO:00069962270.100
Yeast Zebrafish Mouse Worm Fly
myotube cell developmentGO:0014904350.094
Zebrafish
macromolecular complex subunit organizationGO:0043933740.093
Zebrafish Worm Fly
regulation of catalytic activityGO:0050790550.090
Mouse
cardiac muscle fiber developmentGO:004873930.087
Mouse
locomotionGO:00400113130.087
Worm Fly
feeding behaviorGO:000763150.084
Worm
anatomical structure homeostasisGO:0060249360.083
regulation of striated muscle contractionGO:000694220.082
cell recognitionGO:0008037190.080
Worm
slow twitch skeletal muscle fiber contractionGO:003144430.079
canonical wnt signaling pathwayGO:0060070480.078
Mouse
regulation of purine nucleotide metabolic processGO:1900542170.078
Mouse
nucleobase containing small molecule metabolic processGO:0055086320.077
Human Mouse Rat Fly
cellular nitrogen compound metabolic processGO:00346412900.077
Human Mouse Rat Fly
segmentationGO:0035282970.076
Zebrafish
post embryonic organ developmentGO:004856940.072
neuron projection developmentGO:00311751800.071
Worm
lipid storageGO:001991510.070
response to activityGO:0014823140.068
Zebrafish
cell projection organizationGO:00300302840.067
Worm
regulation of metabolic processGO:00192223590.067
Mouse Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.067
cardiac ventricle morphogenesisGO:000320870.065
Human
cell part morphogenesisGO:00329902460.065
purine containing compound metabolic processGO:0072521290.064
Human Mouse Rat Fly
neuron projection morphogenesisGO:00488121610.062
cellular nitrogen compound biosynthetic processGO:00442712180.062
Mouse
small molecule metabolic processGO:0044281770.059
Human Mouse Rat Fly
carbohydrate derivative metabolic processGO:1901135610.059
Human Mouse Rat Fly
nuclear divisionGO:0000280230.059
response to reactive oxygen speciesGO:000030250.057
Rat
cardiocyte differentiationGO:0035051440.053
Mouse
axon developmentGO:00615641660.052
Worm
heterocycle biosynthetic processGO:00181302150.052
Mouse
stem cell proliferationGO:007208940.051
cellular protein complex assemblyGO:0043623190.051
Zebrafish Worm Fly
nucleoside phosphate metabolic processGO:0006753280.050
Human Mouse Rat Fly
vasculature developmentGO:00019442780.046
ribonucleoside metabolic processGO:0009119110.046
Human Mouse Rat Fly
regulation of system processGO:0044057400.045
Human Mouse
generation of neuronsGO:00486993850.045
Worm
regionalizationGO:00030022740.044
Zebrafish
reproductionGO:0000003400.044
Worm Fly
regulation of gene expressionGO:00104682650.044
Mouse Fly
regulation of biosynthetic processGO:00098892500.043
Mouse
rna modificationGO:000945120.042
response to stressGO:00069502630.042
Rat
cell cycleGO:0007049930.041
Yeast
cell cycle processGO:0022402530.041
Yeast
eye developmentGO:00016542770.041
cytoskeleton organizationGO:0007010960.041
Yeast Zebrafish Mouse Worm Fly
muscle tissue morphogenesisGO:006041570.041
Human
behaviorGO:0007610740.041
Worm
regulation of cellular biosynthetic processGO:00313262450.040
Mouse
purine nucleotide metabolic processGO:0006163270.040
Human Mouse Rat Fly
organelle fissionGO:0048285230.039
cell morphogenesisGO:00009022890.039
biosynthetic processGO:00090582940.039
Mouse
regulation of multicellular organismal processGO:00512392770.038
Human Mouse
neuron differentiationGO:00301823530.038
Worm
maintenance of locationGO:005123540.037
regulation of nucleobase containing compound metabolic processGO:00192192500.037
Mouse
regulation of cellular metabolic processGO:00313233200.037
Mouse
nucleic acid templated transcriptionGO:00976591810.036
Mouse
regulation of heart growthGO:006042020.036
Mouse
sensory organ developmentGO:00074233930.035
organic cyclic compound biosynthetic processGO:19013622230.035
Mouse
organonitrogen compound metabolic processGO:1901564740.034
Human Mouse Rat Fly
phosphorus metabolic processGO:00067931090.034
Human Mouse Rat Fly
muscle cell cellular homeostasisGO:004671650.033
adult behaviorGO:003053420.032
ribonucleotide metabolic processGO:0009259270.031
Human Mouse Rat Fly
cytokinetic processGO:003250620.031
Yeast
body morphogenesisGO:0010171160.031
Worm
positive regulation of cellular component biogenesisGO:004408930.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
Mouse
organic substance biosynthetic processGO:19015762890.030
Mouse
membrane fusionGO:006102520.030
reactive oxygen species biosynthetic processGO:190340910.029
hatchingGO:003518840.029
multicellular organism reproductionGO:0032504350.028
Worm Fly
synaptic growth at neuromuscular junctionGO:005112420.028
regulation of skeletal muscle tissue developmentGO:004864140.026
macromolecular complex assemblyGO:0065003350.026
Zebrafish Worm Fly
blood vessel developmentGO:00015682460.026
mitotic nuclear divisionGO:0007067180.026
neuroblast proliferationGO:000740520.026
single organism membrane fusionGO:004480120.025
multicellular organism growthGO:003526440.025
heart loopingGO:0001947940.025
intracellular mrna localizationGO:000829810.025
regulation of primary metabolic processGO:00800903110.025
Mouse
homeostatic processGO:00425921420.025
bmp signaling pathwayGO:0030509520.025
Mouse
cell divisionGO:0051301200.025
Yeast
purine ribonucleoside triphosphate catabolic processGO:000920760.024
Human Mouse Rat Fly
nucleobase containing compound biosynthetic processGO:00346542050.024
Mouse
regulation of protein complex assemblyGO:004325430.024
epithelial tube morphogenesisGO:00605621480.023
embryo development ending in birth or egg hatchingGO:00097922710.023
Zebrafish Mouse Worm
oocyte anterior posterior axis specificationGO:000731440.022
positive regulation of muscle organ developmentGO:004863610.022
macromolecule biosynthetic processGO:00090592270.021
Mouse
mitochondrion organizationGO:000700540.021
regulation of reproductive processGO:200024140.021
regulation of protein polymerizationGO:003227120.021
nucleic acid metabolic processGO:00903042440.021
Mouse
cell matrix adhesionGO:000716040.021
axonogenesisGO:00074091520.021
cellular aromatic compound metabolic processGO:00067252950.021
Human Mouse Rat Fly
regulation of rna metabolic processGO:00512522240.021
Mouse
positive regulation of striated muscle tissue developmentGO:004584410.021
cardiac chamber morphogenesisGO:0003206120.021
Human
cellular response to nutrient levelsGO:003166920.021
lymphoid lineage cell migration into thymusGO:009753540.021
regulation of ion transmembrane transporter activityGO:003241220.021
compound eye developmentGO:004874920.020
mesoderm developmentGO:0007498880.020
embryonic organ developmentGO:00485683810.020
developmental programmed cell deathGO:001062340.020
organic substance catabolic processGO:1901575280.020
Human Mouse Rat Fly
detection of stimulus involved in sensory perceptionGO:0050906210.020
regulation of protein complex disassemblyGO:004324410.020
modification dependent macromolecule catabolic processGO:004363230.020
nitric oxide metabolic processGO:004620920.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
Mouse
positive regulation of cellular catabolic processGO:003133130.020
positive regulation of cell cycleGO:004578730.019
agingGO:000756820.019
regulation of blood vessel sizeGO:005088020.019
signal transduction in absence of ligandGO:003803410.019
regulation of synapse assemblyGO:005196330.019
protein metabolic processGO:00195381830.019
regulation of heart contractionGO:0008016320.018
Human Mouse
modification dependent protein catabolic processGO:001994130.018
regulation of circadian sleep wake cycleGO:004274910.018
catabolic processGO:0009056320.018
Human Mouse Rat Fly
regulation of muscle system processGO:009025750.018
Mouse
regulation of tube sizeGO:003515020.018
meiotic nuclear divisionGO:000712640.018
urogenital system developmentGO:0001655970.018
stem cell divisionGO:001714510.018
heart trabecula morphogenesisGO:006138420.018
organism emergence from protective structureGO:007168440.017
regulation of organ growthGO:004662030.017
Mouse
reactive nitrogen species metabolic processGO:200105700.017
regulation of skeletal muscle fiber developmentGO:004874220.017
protein localization to plasma membraneGO:007265910.017
cellular amine metabolic processGO:004410620.017
response to temperature stimulusGO:0009266150.017
Rat
signal transductionGO:00071654550.017
Mouse Worm
regulation of autophagyGO:001050630.017
protein depolymerizationGO:005126110.017
posttranscriptional regulation of gene expressionGO:0010608140.017
Fly
cardiac atrium developmentGO:000323040.017
Human
regulation of myotube differentiationGO:001083020.017
regulation of nucleotide metabolic processGO:0006140170.017
Mouse
positive regulation of catabolic processGO:000989640.017
cellular macromolecule biosynthetic processGO:00346452240.017
Mouse
pole plasm assemblyGO:000731540.017
muscle cell migrationGO:001481240.017
regulation of multicellular organism growthGO:004001440.017
regulation of dendrite developmentGO:005077330.016
venous blood vessel morphogenesisGO:004884530.016
female gonad developmentGO:000858540.016
nucleobase containing compound metabolic processGO:00061392740.016
Human Mouse Rat Fly
cell morphogenesis involved in differentiationGO:00009041950.016
cellular macromolecule metabolic processGO:00442603910.016
Mouse
guanosine containing compound metabolic processGO:190106840.016
immune system processGO:00023762410.016
carbohydrate biosynthetic processGO:001605110.016
regulation of metal ion transportGO:001095940.016
smooth muscle contractionGO:000693920.016
cellular component disassemblyGO:002241110.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
transportGO:00068102200.016
Worm
negative regulation of protein phosphorylationGO:000193340.016
amine metabolic processGO:000930820.015
rna metabolic processGO:00160702190.015
Mouse
brain developmentGO:00074202930.015
embryonic pattern specificationGO:0009880440.015
Zebrafish
mitotic cell cycleGO:0000278640.015
positive regulation of nucleoside metabolic processGO:004597910.015
rna localizationGO:000640340.015
venous blood vessel developmentGO:006084190.015
regulation of growthGO:0040008420.015
Mouse
aromatic compound biosynthetic processGO:00194382170.015
Mouse
neuron recognitionGO:0008038180.015
Worm
ventricular cardiac myofibril assemblyGO:005500540.015
response to external biotic stimulusGO:0043207970.015
regulation of bindingGO:005109830.015
cellular response to starvationGO:000926710.015
regulation of cell shapeGO:000836010.015
organic cyclic compound catabolic processGO:1901361150.015
Human Mouse Rat Fly
regulation of transmembrane transporter activityGO:002289820.015
regulation of transporter activityGO:003240920.015
trabecula morphogenesisGO:006138320.015
response to drugGO:004249330.015
protein localization to nucleusGO:003450430.015
developmental growthGO:00485891660.015
Mouse
meiotic cell cycle processGO:190304630.014
aromatic compound catabolic processGO:0019439150.014
Human Mouse Rat Fly
blood vessel morphogenesisGO:00485142160.014
nitric oxide biosynthetic processGO:000680920.014
purine nucleoside monophosphate metabolic processGO:000912650.014
Human Mouse Rat Fly
organophosphate metabolic processGO:0019637370.014
Human Mouse Rat Fly
macromolecular complex disassemblyGO:003298410.014
protein polymerizationGO:005125840.014
protein acetylationGO:000647320.014
regulation of cellular ketone metabolic processGO:001056570.013
cell surface receptor signaling pathwayGO:00071663250.013
Mouse
regulation of cellular amine metabolic processGO:003323800.013
protein complex subunit organizationGO:0071822460.013
Zebrafish Worm Fly
regulation of mrna processingGO:005068430.013
regulation of phGO:000688530.013
positive regulation of metabolic processGO:00098931080.013
protein complex disassemblyGO:004324110.013
purine ribonucleoside metabolic processGO:0046128100.013
Human Mouse Rat Fly
response to abiotic stimulusGO:00096281220.013
Rat
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
cellular ketone metabolic processGO:0042180110.013
regulation of gtpase activityGO:004308720.013
apoptotic process involved in morphogenesisGO:006056120.013
cellular response to chemical stimulusGO:00708871570.013
cellular carbohydrate metabolic processGO:004426240.013
purine ribonucleoside catabolic processGO:004613060.013
Human Mouse Rat Fly
circadian sleep wake cycleGO:004274520.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of molecular functionGO:0065009700.012
Mouse
cellular protein catabolic processGO:004425740.012
positive regulation of muscle tissue developmentGO:190186310.012
lateral line developmentGO:0048882660.012
meiotic chromosome segregationGO:004513230.012
mesenchymal cell proliferationGO:001046310.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of nitrogen compound metabolic processGO:00511712510.012
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of transportGO:005105020.012
actin filament polymerizationGO:003004120.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
development of primary female sexual characteristicsGO:004654540.012
regulation of wound healingGO:006104120.012
response to oxidative stressGO:0006979110.012
Rat
regulation of muscle hypertrophyGO:001474320.012
ribonucleoside triphosphate metabolic processGO:000919990.012
Human Mouse Rat Fly
regulation of organelle assemblyGO:190211540.012
single organism reproductive processGO:0044702400.012
Fly
zymogen activationGO:003163830.012
macromolecule catabolic processGO:0009057150.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of synapse organizationGO:005080730.011
autophagyGO:000691440.011
purine nucleoside triphosphate metabolic processGO:000914490.011
Human Mouse Rat Fly
regulation of nitric oxide mediated signal transductionGO:001074910.011
positive regulation of protein complex assemblyGO:003133420.011
protein complex biogenesisGO:0070271300.011
Zebrafish Worm Fly
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
i kappab kinase nf kappab signalingGO:000724940.011
cellular protein complex disassemblyGO:004362410.011
positive regulation of neuron deathGO:190121610.011
apoptotic process involved in developmentGO:190274220.011
protein acylationGO:004354330.011
regulation of rna biosynthetic processGO:20011412130.011
Mouse
regulation of calcium ion transportGO:005192420.011
positive regulation of cytoskeleton organizationGO:005149530.011
proteasomal protein catabolic processGO:001049820.011
cardiac myofibril assemblyGO:005500390.011
positive regulation of nucleotide catabolic processGO:003081310.011
response to copper ionGO:0046688130.011
regulation of sarcomere organizationGO:006029720.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of protein catabolic processGO:004217610.011
tissue remodelingGO:004877140.011
positive regulation of gene expressionGO:0010628710.010
cellular protein metabolic processGO:00442671290.010
sequestering of calcium ionGO:005120830.010
calcium mediated signalingGO:001972220.010
regulation of protein ubiquitinationGO:003139630.010
head developmentGO:00603223030.010
monovalent inorganic cation transportGO:0015672420.010
embryonic organ morphogenesisGO:00485622740.010
cognitionGO:005089010.010
regulation of response to stimulusGO:00485832690.010
Mouse
lymphoid lineage cell migrationGO:009753440.010
regulation of gtp catabolic processGO:003312420.010
establishment of localizationGO:00512342440.010
Worm

smyhc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.389
Human
musculoskeletal system diseaseDOID:1700.389
Human
muscular diseaseDOID:008000000.389
Human
intrinsic cardiomyopathyDOID:006003600.291
Human
cardiovascular system diseaseDOID:128700.291
Human
muscle tissue diseaseDOID:6600.291
Human
cardiomyopathyDOID:005070000.291
Human
heart diseaseDOID:11400.291
Human
myopathyDOID:42300.291
Human
distal arthrogryposisDOID:005064600.078
hypertrophic cardiomyopathyDOID:1198400.077
Human
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
organ system cancerDOID:005068600.011