Danio rerio

0 known processes

smyhc3

slow myosin heavy chain 3

smyhc3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.155
Worm
neuron differentiationGO:00301823530.137
Worm
regulation of blood pressureGO:000821710.124
Mouse
muscle cell developmentGO:00550011150.118
Zebrafish Mouse Worm Fly
striated muscle cell developmentGO:00550021080.114
Zebrafish Mouse Worm Fly
purine nucleoside monophosphate catabolic processGO:000912840.109
Human Mouse Rat Fly
chordate embryonic developmentGO:00430092710.109
Zebrafish Mouse
sensory organ developmentGO:00074233930.102
protein stabilizationGO:005082120.098
Fly
inositol lipid mediated signalingGO:004801720.084
Worm
post embryonic morphogenesisGO:000988640.081
ribonucleoside monophosphate catabolic processGO:000915840.079
Human Mouse Rat Fly
aromatic compound biosynthetic processGO:00194382170.078
Mouse
musculoskeletal movementGO:005088180.075
Zebrafish
cytoskeleton dependent cytokinesisGO:006164030.075
Yeast
nucleobase containing compound biosynthetic processGO:00346542050.074
Mouse
nucleoside monophosphate catabolic processGO:000912540.074
Human Mouse Rat Fly
ventricular cardiac muscle tissue morphogenesisGO:005501020.071
Human
cytokinesisGO:000091030.070
Yeast
regulation of nucleoside metabolic processGO:000911820.069
Mouse
regulation of nucleotide catabolic processGO:003081120.068
Mouse
somatic muscle developmentGO:000752540.066
Fly
response to stressGO:00069502630.065
Rat
atp catabolic processGO:000620040.064
Human Mouse Rat Fly
heterocycle biosynthetic processGO:00181302150.061
Mouse
developmental growthGO:00485891660.056
Mouse
axon developmentGO:00615641660.056
Worm
purine ribonucleoside monophosphate catabolic processGO:000916940.056
Human Mouse Rat Fly
ventricular cardiac muscle tissue developmentGO:000322930.055
Human
actin mediated cell contractionGO:007025210.055
Human
signal transductionGO:00071654550.055
Mouse Worm
regulation of purine nucleotide catabolic processGO:003312120.054
Mouse
axonogenesisGO:00074091520.054
cell surface receptor signaling pathwayGO:00071663250.053
Mouse
multi organism processGO:00517041340.052
Worm Fly
establishment of localizationGO:00512342440.049
Worm
multicellular organism growthGO:003526440.049
neuron developmentGO:00486662620.048
Worm
directional locomotionGO:003305810.046
generation of neuronsGO:00486993850.045
Worm
nucleic acid templated transcriptionGO:00976591810.044
Mouse
locomotionGO:00400113130.044
Worm Fly
neuron projection developmentGO:00311751800.043
Worm
striated muscle cell differentiationGO:00511461290.043
Zebrafish Mouse Worm Fly
somitogenesisGO:0001756870.041
Zebrafish
cellular component morphogenesisGO:00329893360.041
Zebrafish Mouse Worm Fly
regulation of macromolecule metabolic processGO:00602553170.040
Mouse Fly
actin filament based movementGO:003004810.040
Human Mouse
locomotory behaviorGO:0007626340.040
Worm
heart developmentGO:00075073130.039
Human Mouse
organic cyclic compound metabolic processGO:19013603010.039
Human Mouse Rat Fly
skeletal myofibril assemblyGO:001486670.039
Zebrafish Worm Fly
somite developmentGO:0061053960.038
Zebrafish
lipid storageGO:001991510.038
cell projection organizationGO:00300302840.038
Worm
cellular biosynthetic processGO:00442492860.038
Mouse
macromolecule biosynthetic processGO:00090592270.037
Mouse
regulation of multicellular organism growthGO:004001440.037
skeletal muscle myosin thick filament assemblyGO:003024150.037
Worm Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.036
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.036
Mouse
regulation of metabolic processGO:00192223590.036
Mouse Fly
cellular component assemblyGO:00226071700.036
Yeast Zebrafish Mouse Worm Fly
myotube cell developmentGO:0014904350.035
Zebrafish
eye developmentGO:00016542770.035
regulation of synapse organizationGO:005080730.034
cell part morphogenesisGO:00329902460.034
positive regulation of cellular component biogenesisGO:004408930.034
skeletal muscle thin filament assemblyGO:003024040.034
Zebrafish
heart morphogenesisGO:00030071560.034
Human
rna metabolic processGO:00160702190.033
Mouse
neuron projection morphogenesisGO:00488121610.033
skeletal muscle organ developmentGO:0060538780.033
Zebrafish
skeletal muscle fiber developmentGO:0048741350.033
Zebrafish
synaptic growth at neuromuscular junctionGO:005112420.033
nitrogen compound metabolic processGO:00068073190.033
Human Mouse Rat Fly
cellular nitrogen compound metabolic processGO:00346412900.033
Human Mouse Rat Fly
embryo development ending in birth or egg hatchingGO:00097922710.032
Zebrafish Mouse Worm
regionalizationGO:00030022740.032
Zebrafish
regulation of cellular metabolic processGO:00313233200.032
Mouse
regulation of biological qualityGO:00650082630.031
Human Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.031
Mouse
agingGO:000756820.030
organic cyclic compound biosynthetic processGO:19013622230.030
Mouse
regulation of multicellular organismal processGO:00512392770.030
Human Mouse
myotube differentiationGO:0014902450.029
Zebrafish
maintenance of locationGO:005123540.029
canonical wnt signaling pathwayGO:0060070480.029
Mouse
muscle fiber developmentGO:0048747520.029
Zebrafish Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.029
Mouse
olfactory lobe developmentGO:002198840.028
sensory perception of chemical stimulusGO:000760630.028
cardiac muscle fiber developmentGO:004873930.028
Mouse
muscle cell differentiationGO:00426921390.028
Zebrafish Mouse Worm Fly
cellular ketone metabolic processGO:0042180110.028
cell morphogenesis involved in neuron differentiationGO:00486671630.027
response to temperature stimulusGO:0009266150.027
Rat
response to abiotic stimulusGO:00096281220.027
Rat
organelle organizationGO:00069962270.026
Yeast Zebrafish Mouse Worm Fly
meiotic nuclear divisionGO:000712640.026
regulation of developmental processGO:00507932470.026
Mouse
multicellular organismal movementGO:005087980.026
Zebrafish
circulatory system processGO:0003013870.026
Human Mouse
system processGO:00030081850.026
Human Zebrafish Mouse Rat Worm Fly
adult behaviorGO:003053420.026
cardiac atrium developmentGO:000323040.026
Human
organic substance biosynthetic processGO:19015762890.025
Mouse
heart contractionGO:0060047710.024
Human Mouse
gene expressionGO:00104672520.024
Mouse Fly
single organism membrane fusionGO:004480120.024
regulation of cellular ketone metabolic processGO:001056570.024
cellular macromolecule metabolic processGO:00442603910.024
Mouse
regulation of cellular amino acid metabolic processGO:000652100.024
blood circulationGO:0008015870.024
Human Mouse
amine metabolic processGO:000930820.024
heterocycle metabolic processGO:00464832900.023
Human Mouse Rat Fly
axonal fasciculationGO:0007413110.023
Worm
cellular component assembly involved in morphogenesisGO:00109271070.023
Zebrafish Mouse Worm Fly
regulation of transcription dna templatedGO:00063552130.023
Mouse
cellular macromolecule biosynthetic processGO:00346452240.023
Mouse
biosynthetic processGO:00090582940.023
Mouse
muscle contractionGO:0006936180.023
Human Zebrafish Mouse Rat Worm Fly
muscle structure developmentGO:00610611960.023
Human Zebrafish Mouse Worm Fly
developmental programmed cell deathGO:001062340.023
regulation of muscle contractionGO:000693730.022
cellular amine metabolic processGO:004410620.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
Mouse
mitochondrion organizationGO:000700540.022
cell morphogenesis involved in differentiationGO:00009041950.022
cellular component biogenesisGO:00440851780.022
Yeast Zebrafish Mouse Worm Fly
cell projection morphogenesisGO:00488582440.022
cell morphogenesisGO:00009022890.022
single organism organelle organizationGO:19025891990.021
Yeast Zebrafish Mouse Worm Fly
sleepGO:003043110.021
meiotic cell cycle processGO:190304630.021
twitch skeletal muscle contractionGO:001472140.021
Zebrafish
female sex differentiationGO:004666040.021
response to external stimulusGO:00096052640.021
single organism metabolic processGO:00447102170.021
Human Mouse Rat Fly
regulation of synapse assemblyGO:005196330.021
voluntary skeletal muscle contractionGO:000301040.021
Zebrafish
cellular response to starvationGO:000926710.020
regulation of cellular amine metabolic processGO:003323800.020
regulation of biosynthetic processGO:00098892500.020
Mouse
regulation of heart growthGO:006042020.020
Mouse
response to chemicalGO:00422213200.020
Rat
regulation of metal ion transportGO:001095940.020
cellular response to nutrient levelsGO:003166920.020
cellular carbohydrate metabolic processGO:004426240.020
regulation of rna metabolic processGO:00512522240.020
Mouse
stem cell proliferationGO:007208940.020
small molecule metabolic processGO:0044281770.019
Human Mouse Rat Fly
rna biosynthetic processGO:00327741810.019
Mouse
stem cell maintenanceGO:001982740.019
regulation of gene expressionGO:00104682650.019
Mouse Fly
cellular aromatic compound metabolic processGO:00067252950.019
Human Mouse Rat Fly
behaviorGO:0007610740.019
Worm
apoptotic process involved in developmentGO:190274220.019
compound eye developmentGO:004874920.019
mechanosensory behaviorGO:000763820.019
anatomical structure homeostasisGO:0060249360.019
skeletal muscle tissue developmentGO:0007519670.019
Zebrafish
brain developmentGO:00074202930.018
organism emergence from protective structureGO:007168440.018
muscle system processGO:0003012200.018
Human Zebrafish Mouse Rat Worm Fly
homeostatic processGO:00425921420.018
olfactory bulb developmentGO:002177240.018
positive regulation of transportGO:005105020.018
bmp signaling pathwayGO:0030509520.018
Mouse
heart processGO:0003015710.018
Human Mouse
regulation of ion transmembrane transporter activityGO:003241220.018
regulation of macromolecule biosynthetic processGO:00105562250.018
Mouse
regulation of primary metabolic processGO:00800903110.018
Mouse
inner ear developmentGO:00488391260.018
regulation of cellular biosynthetic processGO:00313262450.018
Mouse
nucleic acid metabolic processGO:00903042440.018
Mouse
membrane fusionGO:006102520.018
embryonic organ morphogenesisGO:00485622740.017
organelle assemblyGO:00709251100.017
Zebrafish Mouse Worm Fly
intracellular signal transductionGO:0035556850.017
Worm
cellular component disassemblyGO:002241110.017
cytokinetic processGO:003250620.017
Yeast
rna localizationGO:000640340.017
positive regulation of cellular catabolic processGO:003133130.017
negative regulation of protein phosphorylationGO:000193340.017
regulation of protein complex assemblyGO:004325430.017
cellular response to external stimulusGO:007149620.017
ion transportGO:00068111140.017
protein polymerizationGO:005125840.017
organic acid metabolic processGO:0006082310.017
cardiac muscle cell developmentGO:0055013200.017
Mouse
positive regulation of cell cycleGO:004578730.017
response to drugGO:004249330.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
female gonad developmentGO:000858540.016
positive regulation of cytoskeleton organizationGO:005149530.016
positive regulation of cellular amine metabolic processGO:003324000.016
cell substrate adhesionGO:003158940.016
cellular response to extracellular stimulusGO:003166820.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
camera type eye developmentGO:00430102220.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of dendrite developmentGO:005077330.016
single organism localizationGO:19025782250.015
septum transversum developmentGO:000334340.015
purine ribonucleotide metabolic processGO:0009150270.015
Human Mouse Rat Fly
regulation of protein polymerizationGO:003227120.015
positive regulation of catabolic processGO:000989640.015
development of primary female sexual characteristicsGO:004654540.015
regulation of cell substrate adhesionGO:001081010.015
regulation of reproductive processGO:200024140.015
positive regulation of protein complex assemblyGO:003133420.015
phagocytosisGO:000690930.015
regulation of circadian sleep wake cycle sleepGO:004518710.015
organonitrogen compound metabolic processGO:1901564740.015
Human Mouse Rat Fly
positive regulation of purine nucleotide catabolic processGO:003312310.015
myofibril assemblyGO:0030239480.015
Zebrafish Mouse Worm Fly
cellular protein catabolic processGO:004425740.015
regulation of bindingGO:005109830.015
regulation of stem cell proliferationGO:007209120.014
ion transmembrane transportGO:0034220910.014
protein acetylationGO:000647320.014
macromolecular complex disassemblyGO:003298410.014
carbohydrate biosynthetic processGO:001605110.014
cellular amino acid metabolic processGO:000652070.014
energy reserve metabolic processGO:000611220.014
regulation of cytokine productionGO:000181730.014
hormone transportGO:000991420.014
regulation of blood vessel sizeGO:005088020.014
regulation of transporter activityGO:003240920.014
positive regulation of nucleoside metabolic processGO:004597910.014
glucose homeostasisGO:004259310.014
signal transduction in absence of ligandGO:003803410.014
gtp metabolic processGO:004603940.014
regulation of cell matrix adhesionGO:000195210.014
posterior lateral line system developmentGO:0048915460.014
muscle organ developmentGO:00075171010.014
Human Zebrafish Mouse Fly
protein complex disassemblyGO:004324110.014
guanosine containing compound metabolic processGO:190106840.013
ribonucleotide metabolic processGO:0009259270.013
Human Mouse Rat Fly
forebrain developmentGO:0030900960.013
regulation of growthGO:0040008420.013
Mouse
regulation of neural precursor cell proliferationGO:200017730.013
response to woundingGO:00096111160.013
regulation of inflammatory responseGO:005072720.013
striated muscle tissue developmentGO:00147061100.013
Human Zebrafish Mouse
post embryonic organ developmentGO:004856940.013
gtp catabolic processGO:000618420.013
smooth muscle contractionGO:000693920.013
modification dependent macromolecule catabolic processGO:004363230.013
extrinsic apoptotic signaling pathwayGO:009719130.013
muscle organ morphogenesisGO:004864480.013
Human
regulation of systemic arterial blood pressureGO:000307310.013
muscle tissue developmentGO:00605371100.013
Human Zebrafish Mouse
regulation of rna biosynthetic processGO:20011412130.013
Mouse
regulation of tube sizeGO:003515020.013
regulation of organ growthGO:004662030.013
Mouse
response to reactive oxygen speciesGO:000030250.013
Rat
epidermal cell fate specificationGO:000995740.013
carboxylic acid metabolic processGO:0019752220.013
protein localization to nucleusGO:003450430.013
proteasomal protein catabolic processGO:001049820.013
protein acylationGO:004354330.013
cardiac muscle tissue morphogenesisGO:005500870.013
Human
transportGO:00068102200.013
Worm
response to hydrogen peroxideGO:004254230.013
regulation of response to stimulusGO:00485832690.013
Mouse
protein homooligomerizationGO:005126030.013
hormone secretionGO:004687920.013
meiotic chromosome segregationGO:004513230.013
macromolecular complex subunit organizationGO:0043933740.013
Zebrafish Worm Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
internal peptidyl lysine acetylationGO:001839320.013
intracellular mrna localizationGO:000829810.013
regulation of cell activationGO:005086510.013
cell cycleGO:0007049930.013
Yeast
establishment of protein localization to organelleGO:007259440.013
regulation of transmembrane transporter activityGO:002289820.013
striated muscle contractionGO:0006941120.012
Human Zebrafish Mouse
nuclear transportGO:005116940.012
circadian sleep wake cycleGO:004274520.012
circadian sleep wake cycle sleepGO:005080210.012
response to organic substanceGO:00100331530.012
guanosine containing compound catabolic processGO:190106920.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
protein importGO:001703830.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
neurotransmitter transportGO:000683620.012
protein depolymerizationGO:005126110.012
regulation of synaptic plasticityGO:004816710.012
regulation of organelle assemblyGO:190211540.012
regulation of gtpase activityGO:004308720.012
lateral line developmentGO:0048882660.012
regulation of mrna processingGO:005068430.012
reproductive processGO:0022414400.012
Worm Fly
regulation of i kappab kinase nf kappab signalingGO:004312240.012
sarcomere organizationGO:0045214260.012
Mouse Fly
regulation of circadian rhythmGO:004275240.012
peptidyl lysine acetylationGO:001839420.012
positive regulation of nucleotide catabolic processGO:003081310.012
tissue remodelingGO:004877140.012
regulation of striated muscle contractionGO:000694220.012
peptide transportGO:001583310.012
regulation of neurotransmitter transportGO:005158810.012
regulation of autophagyGO:001050630.012
head developmentGO:00603223030.012
phosphatidylinositol 3 kinase signalingGO:001406520.012
internal protein amino acid acetylationGO:000647520.012
regulation of purine nucleotide metabolic processGO:1900542170.012
Mouse
carbohydrate homeostasisGO:003350010.012
retina development in camera type eyeGO:00600411460.012
nucleobase containing small molecule metabolic processGO:0055086320.012
Human Mouse Rat Fly
autophagyGO:000691440.012
regulation of developmental growthGO:0048638380.012
Mouse
stem cell divisionGO:001714510.012
morphogenesis of an epitheliumGO:00020093330.012
modification dependent protein catabolic processGO:001994130.012
blood vessel morphogenesisGO:00485142160.011
actin filament polymerizationGO:003004120.011
lipid homeostasisGO:005508830.011
hatchingGO:003518840.011
protein localization to plasma membraneGO:007265910.011
adherens junction organizationGO:003433240.011
transcription dna templatedGO:00063511810.011
Mouse
interspecies interaction between organismsGO:004441940.011
b cell activationGO:004211320.011
central nervous system developmentGO:00074173870.011
stem cell fate commitmentGO:004886510.011
regulation of protein complex disassemblyGO:004324410.011
regulation of protein catabolic processGO:004217610.011
regulation of skeletal muscle tissue developmentGO:004864140.011
response to oxidative stressGO:0006979110.011
Rat
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of cytoplasmic transportGO:190364940.011
cognitionGO:005089010.011
nuclear importGO:005117030.011
sequestering of calcium ionGO:005120830.011
positive regulation of gtpase activityGO:004354710.011
response to hexoseGO:000974630.011
synaptic vesicle transportGO:004848910.011
actin polymerization or depolymerizationGO:000815420.011
polarized epithelial cell differentiationGO:003085940.011
phagocytosis engulfmentGO:000691110.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
centrosome organizationGO:005129710.011
defense response to fungusGO:005083220.011
response to carbohydrateGO:000974330.011
regulation of gtp catabolic processGO:003312420.011
regulation of cell developmentGO:00602841000.011
cell substrate adherens junction assemblyGO:000704510.011
positive regulation of epithelial cell differentiationGO:003085820.011
vasculature developmentGO:00019442780.011
nucleobase containing compound metabolic processGO:00061392740.011
Human Mouse Rat Fly
neuromuscular synaptic transmissionGO:000727420.011
regulation of wound healingGO:006104120.010
segmentationGO:0035282970.010
Zebrafish
cardiac ventricle developmentGO:000323190.010
Human
posttranscriptional regulation of gene expressionGO:0010608140.010
Fly
macromolecular complex assemblyGO:0065003350.010
Zebrafish Worm Fly
eye morphogenesisGO:00485921440.010
response to other organismGO:0051707970.010
skeletal muscle contractionGO:000300950.010
Zebrafish
positive regulation of biological processGO:00485182530.010
protein metabolic processGO:00195381830.010
macroautophagyGO:001623610.010
entrainment of circadian clockGO:000964920.010
er nucleus signaling pathwayGO:000698420.010
cellular component movementGO:00069283350.010
Human Mouse Fly
oxoacid metabolic processGO:0043436310.010
oocyte anterior posterior axis specificationGO:000731440.010
cardiocyte differentiationGO:0035051440.010
Mouse
neuroblast proliferationGO:000740520.010
regulation of sequestering of calcium ionGO:005128240.010
response to monosaccharideGO:003428430.010
pole plasm assemblyGO:000731540.010
striated muscle myosin thick filament assemblyGO:007168860.010
Zebrafish Worm Fly
cytoplasm organizationGO:000702840.010
sequestering of metal ionGO:005123830.010
negative regulation of mapk cascadeGO:004340940.010
lamellipodium organizationGO:009758110.010
regulation of endocrine processGO:004406020.010

smyhc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.068
Human
musculoskeletal system diseaseDOID:1700.068
Human
muscular diseaseDOID:008000000.068
Human
muscle tissue diseaseDOID:6600.068
Human
disease of anatomical entityDOID:700.068
Human
cardiomyopathyDOID:005070000.055
Human
intrinsic cardiomyopathyDOID:006003600.055
Human
cardiovascular system diseaseDOID:128700.055
Human
heart diseaseDOID:11400.055
Human
hypertrophic cardiomyopathyDOID:1198400.033
Human
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.012