Danio rerio

69 known processes

tdp2b

tyrosyl-DNA phosphodiesterase 2b

(Aliases: ttrap,ttrapl,tdp2)

tdp2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nitrogen compound metabolic processGO:00068073190.307
cellular nitrogen compound metabolic processGO:00346412900.300
cellular biosynthetic processGO:00442492860.289
organelle organizationGO:00069962270.281
organic cyclic compound biosynthetic processGO:19013622230.278
regulation of nucleobase containing compound metabolic processGO:00192192500.261
organic substance biosynthetic processGO:19015762890.236
cellular macromolecule metabolic processGO:00442603910.235
cellular aromatic compound metabolic processGO:00067252950.210
biosynthetic processGO:00090582940.196
regulation of primary metabolic processGO:00800903110.186
macromolecule biosynthetic processGO:00090592270.183
nucleic acid templated transcriptionGO:00976591810.175
nucleobase containing compound biosynthetic processGO:00346542050.171
aromatic compound biosynthetic processGO:00194382170.168
determination of left right symmetryGO:00073681790.154
positive regulation of cellular processGO:00485222010.147
specification of symmetryGO:00097992040.143
heterocycle metabolic processGO:00464832900.135
cellular macromolecule biosynthetic processGO:00346452240.132
regulation of cellular macromolecule biosynthetic processGO:20001122220.129
regulation of nitrogen compound metabolic processGO:00511712510.119
regulation of rna biosynthetic processGO:20011412130.118
regulation of biosynthetic processGO:00098892500.116
regulation of rna metabolic processGO:00512522240.116
nucleic acid metabolic processGO:00903042440.113
cellular nitrogen compound biosynthetic processGO:00442712180.113
heterocycle biosynthetic processGO:00181302150.106
regulation of metabolic processGO:00192223590.096
regulation of transcription dna templatedGO:00063552130.095
rna metabolic processGO:00160702190.093
regulation of nucleic acid templated transcriptionGO:19035062130.092
regulation of gene expressionGO:00104682650.091
regulation of macromolecule biosynthetic processGO:00105562250.090
rna biosynthetic processGO:00327741810.082
regulation of cellular biosynthetic processGO:00313262450.073
regulation of cellular metabolic processGO:00313233200.071
regulation of macromolecule metabolic processGO:00602553170.071
organic cyclic compound metabolic processGO:19013603010.070
transcription dna templatedGO:00063511810.068
organonitrogen compound metabolic processGO:1901564740.067
gene expressionGO:00104672520.063
nucleobase containing compound metabolic processGO:00061392740.062
regulation of bindingGO:005109830.054
cellular protein metabolic processGO:00442671290.052
negative regulation of cellular processGO:00485232830.051
multi organism processGO:00517041340.050
peptidyl lysine acetylationGO:001839420.049
positive regulation of biosynthetic processGO:0009891680.045
macromolecular complex subunit organizationGO:0043933740.044
positive regulation of macromolecule biosynthetic processGO:0010557590.043
positive regulation of biological processGO:00485182530.042
protein metabolic processGO:00195381830.041
spindle assembly involved in mitosisGO:009030710.039
cell morphogenesisGO:00009022890.037
spindle assemblyGO:005122520.037
negative regulation of nitrogen compound metabolic processGO:0051172590.036
mitotic dna integrity checkpointGO:004477440.036
cell cycleGO:0007049930.036
kidney developmentGO:0001822920.035
cellular component assemblyGO:00226071700.035
response to stressGO:00069502630.034
regulation of multicellular organismal developmentGO:20000262230.034
negative regulation of biological processGO:00485193040.034
meiotic chromosome segregationGO:004513230.033
maintenance of locationGO:005123540.033
cellular component biogenesisGO:00440851780.033
macromolecular complex assemblyGO:0065003350.032
negative regulation of metabolic processGO:0009892860.030
regulation of signalingGO:00230512350.029
protein acylationGO:004354330.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
mitotic cell cycle embryonicGO:004544820.029
cellular protein modification processGO:00064641000.028
regulation of cell deathGO:00109411030.027
single organism metabolic processGO:00447102170.027
macromolecule modificationGO:00434121110.027
determination of bilateral symmetryGO:00098552040.026
convergent extensionGO:00600261180.026
microtubule organizing center organizationGO:003102310.026
positive regulation of muscle organ developmentGO:004863610.026
phosphorus metabolic processGO:00067931090.026
locomotionGO:00400113130.025
positive regulation of cellular biosynthetic processGO:0031328680.025
amine metabolic processGO:000930820.024
transcription from rna polymerase ii promoterGO:0006366800.024
mitotic dna damage checkpointGO:004477340.024
dna catabolic processGO:000630810.024
sensory organ developmentGO:00074233930.024
small molecule metabolic processGO:0044281770.024
cellular component movementGO:00069283350.024
microtubule cytoskeleton organization involved in mitosisGO:190285010.024
urogenital system developmentGO:0001655970.023
blood vessel developmentGO:00015682460.023
negative regulation of protein phosphorylationGO:000193340.023
g2 m transition of mitotic cell cycleGO:000008640.022
regulation of multicellular organismal processGO:00512392770.022
carbohydrate derivative metabolic processGO:1901135610.022
pole plasm assemblyGO:000731540.022
immune system developmentGO:00025201910.021
regulation of protein ubiquitinationGO:003139630.021
positive regulation of transcription dna templatedGO:0045893570.021
single organism organelle organizationGO:19025891990.020
positive regulation of cellular component biogenesisGO:004408930.020
regulation of cell differentiationGO:00455951420.020
stem cell maintenanceGO:001982740.020
camera type eye developmentGO:00430102220.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.020
negative regulation of cellular biosynthetic processGO:0031327550.020
cytokinesisGO:000091030.020
phosphorylationGO:0016310690.020
g2 dna damage checkpointGO:003157230.019
protein acetylationGO:000647320.019
spliceosomal snrnp assemblyGO:000038720.019
regulation of apoptotic processGO:0042981980.019
cellular amine metabolic processGO:004410620.019
negative regulation of dna metabolic processGO:005105340.019
mitochondrial transportGO:000683920.019
regulation of response to stimulusGO:00485832690.019
regulation of molecular functionGO:0065009700.019
response to organic substanceGO:00100331530.019
kupffer s vesicle developmentGO:0070121500.019
b cell activationGO:004211320.019
cell motilityGO:00488702440.018
internal protein amino acid acetylationGO:000647520.018
meiotic nuclear divisionGO:000712640.018
cellular response to oxygen levelsGO:007145310.018
axis specificationGO:0009798430.018
apoptotic processGO:00069151160.018
larval developmentGO:000216420.018
humoral immune response mediated by circulating immunoglobulinGO:000245530.018
meiotic cell cycle processGO:190304630.018
hemopoiesisGO:00300971830.018
immune system processGO:00023762410.018
growthGO:00400071740.018
positive regulation of transportGO:005105020.018
regulation of cytokine productionGO:000181730.018
cell proliferationGO:0008283800.017
positive regulation of nucleic acid templated transcriptionGO:1903508570.017
negative regulation of rna biosynthetic processGO:1902679450.017
dorsal ventral pattern formationGO:00099531250.017
anterior posterior axis specificationGO:0009948200.017
negative regulation of cellular metabolic processGO:0031324770.017
immunoglobulin mediated immune responseGO:001606430.017
epithelial tube morphogenesisGO:00605621480.016
vasculature developmentGO:00019442780.016
embryonic organ developmentGO:00485683810.016
peptidyl lysine dimethylationGO:001802710.016
cellular localizationGO:0051641970.016
mitotic sister chromatid segregationGO:000007060.016
ribonucleoside monophosphate catabolic processGO:000915840.015
pronephros developmentGO:0048793690.015
regulation of cellular amine metabolic processGO:003323800.015
mitochondrion organizationGO:000700540.015
positive regulation of gene expressionGO:0010628710.015
cellular component morphogenesisGO:00329893360.015
protein homooligomerizationGO:005126030.015
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
hepaticobiliary system developmentGO:0061008980.015
regulation of dna replicationGO:000627530.015
mesoderm developmentGO:0007498880.015
covalent chromatin modificationGO:0016569200.015
negative regulation of kinase activityGO:003367340.015
regulation of biological qualityGO:00650082630.015
cellular response to hypoxiaGO:007145610.014
protein complex biogenesisGO:0070271300.014
positive regulation of rna biosynthetic processGO:1902680570.014
cellular ketone metabolic processGO:0042180110.014
cellular response to decreased oxygen levelsGO:003629410.014
positive regulation of cell cycleGO:004578730.014
eye developmentGO:00016542770.014
cilium morphogenesisGO:0060271850.014
regulation of cell proliferationGO:0042127370.014
oocyte anterior posterior axis specificationGO:000731440.014
protein targeting to nucleusGO:004474430.014
ribonucleotide metabolic processGO:0009259270.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
hormone transportGO:000991420.014
viral processGO:001603210.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
recombinational repairGO:000072510.014
protein complex assemblyGO:0006461300.014
protein modification processGO:00362111000.014
positive regulation of cellular catabolic processGO:003133130.014
nucleocytoplasmic transportGO:000691340.014
positive regulation of cytokine productionGO:000181920.014
oxoacid metabolic processGO:0043436310.014
phosphate containing compound metabolic processGO:00067961080.014
cell surface receptor signaling pathwayGO:00071663250.014
internal peptidyl lysine acetylationGO:001839320.014
positive regulation of translationGO:004572710.014
determination of heart left right asymmetryGO:00613711170.014
cell killingGO:000190620.014
blood vessel morphogenesisGO:00485142160.014
ovarian follicle developmentGO:000154120.014
negative regulation of transcription dna templatedGO:0045892450.014
fertilizationGO:000956630.014
regulation of cell cycleGO:0051726520.013
anterior posterior pattern specificationGO:00099521520.013
spermatid developmentGO:000728620.013
heart developmentGO:00075073130.013
response to abiotic stimulusGO:00096281220.013
negative regulation of dna replicationGO:000815620.013
positive regulation of macromolecule metabolic processGO:0010604930.013
maternal determination of anterior posterior axis embryoGO:000835840.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
regulation of cellular amino acid metabolic processGO:000652100.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
response to external stimulusGO:00096052640.013
positive regulation of metabolic processGO:00098931080.013
nucleoside monophosphate catabolic processGO:000912540.013
morphogenesis of an epitheliumGO:00020093330.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
nuclear transportGO:005116940.012
atp catabolic processGO:000620040.012
centrosome cycleGO:000709810.012
cell projection morphogenesisGO:00488582440.012
cellular response to organic substanceGO:00713101050.012
regulation of reproductive processGO:200024140.012
spermatid differentiationGO:004851520.012
response to bacteriumGO:0009617580.012
organic acid metabolic processGO:0006082310.012
microtubule based processGO:0007017600.012
embryonic digestive tract developmentGO:004856640.012
response to monosaccharideGO:003428430.012
response to uvGO:000941130.012
developmental growthGO:00485891660.012
gamete generationGO:0007276330.012
cellular response to chemical stimulusGO:00708871570.012
septum transversum developmentGO:000334340.012
cardiocyte differentiationGO:0035051440.012
specification of axis polarityGO:006500140.011
chromatin organizationGO:0006325220.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
cell projection organizationGO:00300302840.011
killing of cells of other organismGO:003164010.011
regulation of cell communicationGO:00106462320.011
positive regulation of muscle tissue developmentGO:190186310.011
central nervous system developmentGO:00074173870.011
positive regulation of cellular metabolic processGO:0031325940.011
positive regulation of cell activationGO:005086710.011
cell deathGO:00082191210.011
negative regulation of gene expressionGO:0010629650.011
regulation of establishment of protein localizationGO:007020140.011
rna localizationGO:000640340.011
multicellular organism reproductionGO:0032504350.011
agingGO:000756820.011
regulation of developmental processGO:00507932470.011
regulation of signal transductionGO:00099662250.011
interspecies interaction between organismsGO:004441940.011
establishment of protein localization to organelleGO:007259440.011
negative regulation of protein kinase activityGO:000646940.011
organelle assemblyGO:00709251100.011
cell part morphogenesisGO:00329902460.011
localization of cellGO:00516742440.011
regulation of cell activationGO:005086510.011
cardiac atrium developmentGO:000323040.011
retina development in camera type eyeGO:00600411460.011
renal system developmentGO:0072001940.011
negative regulation of macromolecule metabolic processGO:0010605760.011
appendage morphogenesisGO:0035107560.011
modification dependent macromolecule catabolic processGO:004363230.011
negative regulation of mitosisGO:004583930.010
cell substrate junction assemblyGO:000704420.010
dna methylation or demethylationGO:004472880.010
negative regulation of signalingGO:0023057960.010
signal transductionGO:00071654550.010
response to carbohydrateGO:000974330.010
regulation of nucleoside metabolic processGO:000911820.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
cellular response to radiationGO:007147840.010
regionalizationGO:00030022740.010
modification dependent protein catabolic processGO:001994130.010
peptide transportGO:001583310.010
neuron differentiationGO:00301823530.010
positive regulation of multi organism processGO:004390230.010

tdp2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
nervous system diseaseDOID:86300.011