Danio rerio

76 known processes

sfpq

splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

(Aliases: zgc:85935,wu:fa11h12,hm:zeh0027,wu:fd10f03)

sfpq biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of metabolic processGO:00192223590.326
Human Mouse
regulation of multicellular organismal processGO:00512392770.283
larval developmentGO:000216420.281
Worm
growthGO:00400071740.212
Worm
regulation of multicellular organismal developmentGO:20000262230.210
regulation of gene expression epigeneticGO:0040029110.201
histone h3 k4 methylationGO:005156820.199
histone modificationGO:0016570200.177
Mouse
macromolecule biosynthetic processGO:00090592270.172
Human Mouse
methylationGO:0032259220.168
regulation of cell differentiationGO:00455951420.164
regulation of nucleic acid templated transcriptionGO:19035062130.163
Human Mouse
meiotic nuclear divisionGO:000712640.162
negative regulation of biological processGO:00485193040.161
embryo development ending in birth or egg hatchingGO:00097922710.149
negative regulation of cellular processGO:00485232830.148
rna metabolic processGO:00160702190.147
Human Mouse
maternal determination of anterior posterior axis embryoGO:000835840.146
ribonucleoside monophosphate catabolic processGO:000915840.140
response to chemicalGO:00422213200.139
Human
positive regulation of biosynthetic processGO:0009891680.128
regulation of multicellular organism growthGO:004001440.127
embryonic organ developmentGO:00485683810.125
regulation of developmental processGO:00507932470.124
negative regulation of nucleobase containing compound metabolic processGO:0045934590.122
Human Mouse
regulation of primary metabolic processGO:00800903110.120
Human Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.119
Human Mouse
organic cyclic compound metabolic processGO:19013603010.116
Human Mouse
skeletal muscle tissue developmentGO:0007519670.114
muscle tissue developmentGO:00605371100.111
organelle organizationGO:00069962270.110
Mouse
response to external stimulusGO:00096052640.103
adult behaviorGO:003053420.099
positive regulation of biological processGO:00485182530.098
Human
somitogenesisGO:0001756870.095
negative regulation of metabolic processGO:0009892860.095
Human Mouse
mitotic cell cycleGO:0000278640.095
positive regulation of cellular metabolic processGO:0031325940.095
negative regulation of gene expressionGO:0010629650.092
Human Mouse
aromatic compound biosynthetic processGO:00194382170.088
Human Mouse
activation of mapkkk activityGO:000018510.086
regulation of anatomical structure morphogenesisGO:00226031300.085
3 utr mediated mrna stabilizationGO:007093530.083
regulation of cellular metabolic processGO:00313233200.081
Human Mouse
central nervous system developmentGO:00074173870.081
blood vessel developmentGO:00015682460.079
cell migrationGO:00164772370.078
pigmentationGO:0043473850.077
regulation of cellular biosynthetic processGO:00313262450.076
Human Mouse
cellular protein metabolic processGO:00442671290.076
Mouse
cellular component assemblyGO:00226071700.076
positive regulation of dna metabolic processGO:005105410.073
regulation of transcription dna templatedGO:00063552130.072
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.071
Human Mouse
single fertilizationGO:000733830.071
cell substrate junction assemblyGO:000704420.070
cellular macromolecule biosynthetic processGO:00346452240.068
Human Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.068
Human Mouse
cellular macromolecule metabolic processGO:00442603910.067
Human Mouse
regulation of macromolecule biosynthetic processGO:00105562250.066
Human Mouse
maintenance of locationGO:005123540.065
regulation of gene expressionGO:00104682650.064
Human Mouse
striated muscle tissue developmentGO:00147061100.063
nucleobase containing compound biosynthetic processGO:00346542050.062
Human Mouse
developmental growthGO:00485891660.062
protein modification processGO:00362111000.062
Mouse
chromatin modificationGO:0016568210.061
Mouse
regulation of mrna processingGO:005068430.060
single organism organelle organizationGO:19025891990.060
Mouse
positive regulation of cellular component biogenesisGO:004408930.059
protein acetylationGO:000647320.058
oocyte anterior posterior axis specificationGO:000731440.058
negative regulation of cellular catabolic processGO:003133030.058
multicellular organism growthGO:003526440.058
negative regulation of nitrogen compound metabolic processGO:0051172590.058
Human Mouse
pole plasm assemblyGO:000731540.057
biosynthetic processGO:00090582940.057
Human Mouse
nuclear pore organizationGO:000699920.056
retina development in camera type eyeGO:00600411460.056
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.055
nitrogen compound metabolic processGO:00068073190.055
Human Mouse
purine nucleoside monophosphate catabolic processGO:000912840.055
positive regulation of metabolic processGO:00098931080.055
rna stabilizationGO:004348940.054
stem cell differentiationGO:00488631170.054
morphogenesis of an epitheliumGO:00020093330.053
symbiosis encompassing mutualism through parasitismGO:004440340.053
heterocycle metabolic processGO:00464832900.053
Human Mouse
heart developmentGO:00075073130.052
chromatin organizationGO:0006325220.051
Mouse
nucleic acid templated transcriptionGO:00976591810.051
Human Mouse
cellular aromatic compound metabolic processGO:00067252950.051
Human Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.050
synaptic growth at neuromuscular junctionGO:005112420.050
establishment of localizationGO:00512342440.050
heterocycle biosynthetic processGO:00181302150.050
Human Mouse
anterior posterior pattern specificationGO:00099521520.050
regulation of alternative mrna splicing via spliceosomeGO:000038110.048
macromolecule methylationGO:0043414190.048
eye developmentGO:00016542770.047
neuronal stem cell maintenanceGO:009715020.047
regulation of cell morphogenesis involved in differentiationGO:0010769380.047
cellular nitrogen compound metabolic processGO:00346412900.047
Human Mouse
rna transportGO:005065820.046
regulation of dna templated transcription elongationGO:003278430.046
organelle fissionGO:0048285230.045
positive regulation of chromatin modificationGO:190331010.045
sarcomerogenesisGO:004876940.045
regulation of meiotic cell cycleGO:005144510.044
heart morphogenesisGO:00030071560.044
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.044
fertilizationGO:000956630.044
cell cycleGO:0007049930.044
vasculature developmentGO:00019442780.044
modification of morphology or physiology of other organismGO:003582140.044
cellular component biogenesisGO:00440851780.044
localization of cellGO:00516742440.043
neuron differentiationGO:00301823530.041
cytoskeleton organizationGO:0007010960.041
blood vessel morphogenesisGO:00485142160.040
digestive tract developmentGO:00485652650.040
organic cyclic compound biosynthetic processGO:19013622230.040
Human Mouse
internal peptidyl lysine acetylationGO:001839320.040
histone methylationGO:0016571130.039
positive regulation of macromolecule biosynthetic processGO:0010557590.039
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.039
organic substance biosynthetic processGO:19015762890.039
Human Mouse
gene silencing by rnaGO:003104740.039
atp catabolic processGO:000620040.038
peptidyl lysine acetylationGO:001839420.038
regulation of cell deathGO:00109411030.038
Human
generation of neuronsGO:00486993850.038
regulation of rna metabolic processGO:00512522240.037
Human Mouse
cellular protein modification processGO:00064641000.037
Mouse
positive regulation of cellular biosynthetic processGO:0031328680.037
lipid storageGO:001991510.037
embryonic heart tube morphogenesisGO:00031431080.037
cellular component morphogenesisGO:00329893360.036
segmentationGO:0035282970.036
negative regulation of cellular biosynthetic processGO:0031327550.036
Human Mouse
transmembrane transportGO:00550851200.036
regulation of cellular component organizationGO:0051128860.036
protein metabolic processGO:00195381830.035
Mouse
internal protein amino acid acetylationGO:000647520.035
mitotic g2 dna damage checkpointGO:000709530.035
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.035
regulation of protein catabolic processGO:004217610.035
dsrna fragmentationGO:003105010.035
nucleic acid transportGO:005065720.034
agingGO:000756820.034
rna localizationGO:000640340.034
signal transductionGO:00071654550.034
Human
digestive tract morphogenesisGO:00485462310.034
ion transportGO:00068111140.033
response to biotic stimulusGO:0009607970.033
transportGO:00068102200.033
hematopoietic or lymphoid organ developmentGO:00485341910.032
negative regulation of macromolecule biosynthetic processGO:0010558480.032
Human Mouse
regulation of cell proliferationGO:0042127370.032
rna biosynthetic processGO:00327741810.031
Human Mouse
gene silencingGO:001645840.031
negative regulation of rna metabolic processGO:0051253480.030
Human Mouse
cell matrix adhesionGO:000716040.030
dna modificationGO:000630480.030
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.029
amine metabolic processGO:000930820.029
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.029
Human Mouse
stem cell developmentGO:0048864820.029
negative regulation of biosynthetic processGO:0009890550.029
Human Mouse
regulation of macromolecule metabolic processGO:00602553170.028
Human Mouse
exocytosisGO:000688710.028
regulation of biosynthetic processGO:00098892500.028
Human Mouse
stem cell maintenanceGO:001982740.028
brain developmentGO:00074202930.028
chordate embryonic developmentGO:00430092710.028
pore complex assemblyGO:004693120.027
extrinsic apoptotic signaling pathwayGO:009719130.027
regulation of cell developmentGO:00602841000.027
determination of left right symmetryGO:00073681790.027
positive regulation of nucleobase containing compound metabolic processGO:0045935690.027
positive regulation of cellular processGO:00485222010.027
Human
adherens junction organizationGO:003433240.027
cardiac muscle myosin thick filament assemblyGO:007169010.026
sensory organ morphogenesisGO:00905962000.026
negative regulation of ras protein signal transductionGO:004658010.026
system processGO:00030081850.026
Fly
regulation of synapse assemblyGO:005196330.025
macromolecule localizationGO:0033036540.025
camera type eye developmentGO:00430102220.025
sensory perception of light stimulusGO:0050953190.025
Fly
multi organism cellular processGO:004476420.025
establishment of protein localization to organelleGO:007259440.024
mitotic dna integrity checkpointGO:004477440.024
regulation of cellular protein catabolic processGO:190336210.024
embryonic heart tube developmentGO:00350501330.024
positive regulation of transportGO:005105020.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
cellular amine metabolic processGO:004410620.023
viral processGO:001603210.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.023
immune system processGO:00023762410.023
alternative mrna splicing via spliceosomeGO:000038010.023
Human
cytokinesisGO:000091030.023
regulation of nervous system developmentGO:0051960900.023
regulation of metal ion transportGO:001095940.023
regulation of cellular amino acid metabolic processGO:000652100.023
mitotic nuclear divisionGO:0007067180.022
cell projection organizationGO:00300302840.022
transcription elongation from rna polymerase ii promoterGO:000636830.022
regionalizationGO:00030022740.022
regulation of organelle assemblyGO:190211540.022
muscle cell developmentGO:00550011150.022
mesenchymal cell developmentGO:0014031780.022
retina morphogenesis in camera type eyeGO:0060042790.022
cellular response to dsrnaGO:007135910.022
positive regulation of neuron apoptotic processGO:004352510.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
Human Mouse
transcription dna templatedGO:00063511810.021
Human Mouse
covalent chromatin modificationGO:0016569200.021
Mouse
intracellular signal transductionGO:0035556850.021
Human
reproductionGO:0000003400.021
Worm Fly
sensory organ developmentGO:00074233930.021
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.021
positive regulation of rna biosynthetic processGO:1902680570.020
protein alkylationGO:0008213130.020
nucleobase containing compound transportGO:001593120.020
transcription from rna polymerase ii promoterGO:0006366800.020
Human
single organism metabolic processGO:00447102170.020
Mouse
cellular component movementGO:00069283350.020
regulation of organelle organizationGO:0033043290.020
positive regulation of gene expressionGO:0010628710.020
nucleoside monophosphate catabolic processGO:000912540.020
response to woundingGO:00096111160.019
protein acylationGO:004354330.019
single organism localizationGO:19025782250.019
positive regulation of dna templated transcription elongationGO:003278610.019
tube morphogenesisGO:00352393490.019
response to uvGO:000941130.019
negative regulation of macromolecule metabolic processGO:0010605760.019
Human Mouse
regulation of epithelial cell proliferationGO:005067830.019
heart loopingGO:0001947940.019
regulation of synapse organizationGO:005080730.019
heart contractionGO:0060047710.019
cell differentiation in spinal cordGO:0021515400.018
positive regulation of chromosome organizationGO:200125210.018
epithelial cell morphogenesisGO:000338220.018
positive regulation of cellular amine metabolic processGO:003324000.018
locomotory behaviorGO:0007626340.018
regulation of neurogenesisGO:0050767870.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
macromolecular complex assemblyGO:0065003350.018
negative regulation of rna splicingGO:003311910.018
regulation of skeletal muscle fiber developmentGO:004874220.018
cellular ketone metabolic processGO:0042180110.018
spermatid differentiationGO:004851520.018
cellular protein catabolic processGO:004425740.017
positive regulation of macromolecule metabolic processGO:0010604930.017
cellular response to external stimulusGO:007149620.017
skeletal muscle organ developmentGO:0060538780.017
g2 m transition of mitotic cell cycleGO:000008640.017
axonogenesisGO:00074091520.017
cell motilityGO:00488702440.017
ion transmembrane transportGO:0034220910.017
gene expressionGO:00104672520.016
Human Mouse
regulation of cellular ketone metabolic processGO:001056570.016
negative regulation of chromosome organizationGO:200125110.016
positive regulation of synapse assemblyGO:005196510.016
positive regulation of cellular protein metabolic processGO:0032270220.016
negative regulation of transcription dna templatedGO:0045892450.016
Human Mouse
negative regulation of cell deathGO:0060548600.016
protein complex subunit organizationGO:0071822460.016
neuron projection extensionGO:1990138450.016
dna templated transcription elongationGO:000635430.016
regulation of cell activationGO:005086510.016
developmental growth involved in morphogenesisGO:0060560860.016
membrane repolarizationGO:008600920.016
cellular localizationGO:0051641970.016
rhythmic processGO:0048511210.016
Mouse
somite developmentGO:0061053960.016
interspecies interaction between organismsGO:004441940.016
regulation of protein complex assemblyGO:004325430.016
regulation of epidermis developmentGO:004568220.016
response to organic substanceGO:00100331530.016
behaviorGO:0007610740.015
Fly
positive regulation of histone modificationGO:003105810.015
regulation of cellular protein metabolic processGO:0032268520.015
posttranscriptional gene silencingGO:001644130.015
convergent extensionGO:00600261180.015
locomotionGO:00400113130.015
ear developmentGO:00435831270.015
regulation of oligodendrocyte differentiationGO:004871310.015
establishment of rna localizationGO:005123630.015
cardiac atrium developmentGO:000323040.015
protein complex biogenesisGO:0070271300.015
cellular biosynthetic processGO:00442492860.015
Human Mouse
posttranscriptional regulation of gene expressionGO:0010608140.015
determination of heart left right asymmetryGO:00613711170.015
positive regulation of chromosome segregationGO:005198410.015
regulation of growthGO:0040008420.015
histone deacetylationGO:001657520.015
Mouse
embryonic digestive tract morphogenesisGO:004855730.014
neurological system processGO:0050877620.014
Fly
negative regulation of nuclear divisionGO:005178430.014
negative regulation of catabolic processGO:000989530.014
regulation of developmental growthGO:0048638380.014
neural crest cell differentiationGO:0014033720.014
foregut morphogenesisGO:000744040.014
adherens junction assemblyGO:003433310.014
mitotic g2 m transition checkpointGO:004481830.014
cell junction organizationGO:0034330110.014
positive regulation of cell cycleGO:004578730.014
hemidesmosome assemblyGO:003158110.014
regulation of signalingGO:00230512350.014
Human
response to stressGO:00069502630.014
regulation of production of molecular mediator of immune responseGO:000270010.014
oxoacid metabolic processGO:0043436310.014
cellular response to extracellular stimulusGO:003166820.014
cell agingGO:000756920.014
compound eye developmentGO:004874920.014
midbrain developmentGO:0030901280.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
circadian rhythmGO:0007623190.013
Mouse
regulation of cell morphogenesisGO:0022604420.013
muscle cell differentiationGO:00426921390.013
regulation of sarcomere organizationGO:006029720.013
embryonic organ morphogenesisGO:00485622740.013
central nervous system neuron differentiationGO:0021953740.013
regulation of cell shapeGO:000836010.013
response to inorganic substanceGO:0010035380.013
response to other organismGO:0051707970.013
intracellular mrna localizationGO:000829810.013
cation transmembrane transportGO:0098655650.013
axon extensionGO:0048675450.013
blood circulationGO:0008015870.013
cell substrate adherens junction assemblyGO:000704510.013
response to drugGO:004249330.013
nuclear migrationGO:000709730.013
mitotic cell cycle processGO:1903047480.013
production of molecular mediator of immune responseGO:000244020.013
protein localizationGO:0008104400.013
cell cycle processGO:0022402530.012
protein complex localizationGO:003150310.012
pigment cell differentiationGO:0050931380.012
regulation of intracellular signal transductionGO:1902531570.012
Human
purine ribonucleoside monophosphate catabolic processGO:000916940.012
heart processGO:0003015710.012
protein secretionGO:000930610.012
positive regulation of catabolic processGO:000989640.012
germ line stem cell maintenanceGO:003071820.012
positive regulation of protein metabolic processGO:0051247230.012
cell part morphogenesisGO:00329902460.012
organonitrogen compound metabolic processGO:1901564740.012
glial cell differentiationGO:0010001420.012
positive regulation of transcription dna templatedGO:0045893570.012
deathGO:00162651210.012
Human
regulation of reproductive processGO:200024140.012
g protein coupled receptor signaling pathwayGO:0007186740.011
regulation of rna biosynthetic processGO:20011412130.011
Human Mouse
regulation of protein transportGO:005122330.011
regulation of mrna stabilityGO:004348840.011
carboxylic acid metabolic processGO:0019752220.011
regulation of cellular amine metabolic processGO:003323800.011
hematopoietic stem cell differentiationGO:0060218200.011
organic acid metabolic processGO:0006082310.011
regulation of mrna splicing via spliceosomeGO:004802430.011
positive regulation of epithelial cell migrationGO:001063420.011
cardiac muscle tissue developmentGO:0048738480.011
calcium ion importGO:007050940.011
regulation of establishment of protein localizationGO:007020140.011
regulation of intracellular protein transportGO:003315730.011
cell surface receptor signaling pathwayGO:00071663250.010
regulation of neural precursor cell proliferationGO:200017730.010
neuroblast proliferationGO:000740520.010
circulatory system processGO:0003013870.010
regulation of biological qualityGO:00650082630.010
exocrine pancreas developmentGO:0031017280.010
microtubule cytoskeleton organization involved in mitosisGO:190285010.010
positive regulation of translationGO:004572710.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
tongue morphogenesisGO:004358730.010
macromolecule modificationGO:00434121110.010
Mouse
polarized epithelial cell differentiationGO:003085940.010
production of small rna involved in gene silencing by rnaGO:007091810.010
neuromuscular synaptic transmissionGO:000727420.010
carbohydrate biosynthetic processGO:001605110.010

sfpq disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
motor neuron diseaseDOID:23100.026
neurodegenerative diseaseDOID:128900.026
nervous system diseaseDOID:86300.026
central nervous system diseaseDOID:33100.026
amyotrophic lateral sclerosisDOID:33200.026
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.015
physical disorderDOID:008001500.011