Danio rerio

0 known processes

slc4a4b

solute carrier family 4, sodium bicarbonate cotransporter, member 4b

(Aliases: nbc1)

slc4a4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anion homeostasisGO:005508190.950
bicarbonate transportGO:001570140.772
Zebrafish Mouse
chloride transportGO:000682180.580
Worm
anion transportGO:0006820380.479
Zebrafish Mouse Worm
ammonia homeostasisGO:009727230.378
nitrogen compound metabolic processGO:00068073190.317
metal ion transportGO:0030001580.310
Zebrafish Mouse
chloride transmembrane transportGO:190247640.285
Worm
hematopoietic or lymphoid organ developmentGO:00485341910.217
Zebrafish
humoral immune response mediated by circulating immunoglobulinGO:000245530.204
inorganic anion transportGO:0015698250.202
Zebrafish Worm
regulation of phGO:000688530.168
cellular response to molecule of bacterial originGO:007121930.155
transmembrane transportGO:00550851200.151
Zebrafish Worm
immune system processGO:00023762410.150
Zebrafish
activation of immune responseGO:000225390.148
ear developmentGO:00435831270.140
ion transportGO:00068111140.126
Zebrafish Mouse Worm
cellular macromolecule biosynthetic processGO:00346452240.122
embryonic cranial skeleton morphogenesisGO:0048701900.121
biosynthetic processGO:00090582940.109
toxin transportGO:190199820.106
Zebrafish
erythrocyte differentiationGO:0030218540.103
Zebrafish
regulation of nucleic acid templated transcriptionGO:19035062130.102
sodium ion transportGO:0006814240.098
Zebrafish Mouse
one carbon compound transportGO:0019755140.092
ammonium transportGO:001569660.092
establishment of localizationGO:00512342440.090
Zebrafish Mouse Worm
cellular response to lipopolysaccharideGO:007122230.086
cation transportGO:0006812810.085
Zebrafish Mouse
monovalent inorganic cation homeostasisGO:005506790.084
monovalent inorganic cation transportGO:0015672420.080
Zebrafish Mouse
positive regulation of map kinase activityGO:004340630.080
cellular component assembly involved in morphogenesisGO:00109271070.076
negative regulation of cysteine type endopeptidase activityGO:200011780.073
protein activation cascadeGO:007237660.071
inorganic anion transmembrane transportGO:0098661100.070
Worm
immunoglobulin mediated immune responseGO:001606430.069
cellular ketone metabolic processGO:0042180110.066
erythrocyte homeostasisGO:0034101550.064
Zebrafish
homeostatic processGO:00425921420.064
Zebrafish
regulation of membrane potentialGO:0042391230.063
regulation of nucleobase containing compound metabolic processGO:00192192500.063
cation homeostasisGO:0055080330.062
response to chemicalGO:00422213200.061
Zebrafish Worm
nucleic acid metabolic processGO:00903042440.060
complement activation classical pathwayGO:000695830.060
sodium ion importGO:009736930.059
response to carbohydrateGO:000974330.059
embryonic viscerocranium morphogenesisGO:0048703520.059
response to stressGO:00069502630.058
mononuclear cell proliferationGO:003294310.057
response to drugGO:004249330.057
Zebrafish
hemopoiesisGO:00300971830.057
Zebrafish
ion transmembrane transportGO:0034220910.055
Zebrafish Worm
regulation of cellular macromolecule biosynthetic processGO:20001122220.055
embryo development ending in birth or egg hatchingGO:00097922710.054
sensory organ developmentGO:00074233930.051
regulation of cellular phGO:003064110.051
regulation of biological qualityGO:00650082630.049
Zebrafish
head developmentGO:00603223030.049
regulation of cellular biosynthetic processGO:00313262450.048
regulation of inflammatory responseGO:005072720.048
cation transmembrane transportGO:0098655650.048
Zebrafish
inner ear developmentGO:00488391260.047
system processGO:00030081850.047
leukocyte proliferationGO:007066110.047
ensheathment of neuronsGO:0007272180.046
sensory system developmentGO:0048880760.046
embryonic organ developmentGO:00485683810.046
Zebrafish
multicellular organismal signalingGO:0035637220.045
positive regulation of catabolic processGO:000989640.045
divalent inorganic anion homeostasisGO:007250550.044
cranial nerve developmentGO:0021545420.043
fatty acid catabolic processGO:000906210.043
camera type eye morphogenesisGO:00485931080.043
myeloid cell differentiationGO:0030099860.043
Zebrafish
cell migrationGO:00164772370.043
regulation of transcription dna templatedGO:00063552130.042
response to salt stressGO:0009651100.042
positive regulation of transportGO:005105020.042
immune system developmentGO:00025201910.042
Zebrafish
organic substance biosynthetic processGO:19015762890.041
blood vessel developmentGO:00015682460.041
myeloid cell homeostasisGO:0002262560.040
Zebrafish
response to monosaccharideGO:003428430.040
inorganic ion transmembrane transportGO:0098660570.040
Zebrafish Worm
antibacterial humoral responseGO:001973120.039
homeostasis of number of cellsGO:0048872620.039
Zebrafish
vasculature developmentGO:00019442780.039
regulation of nitrogen compound metabolic processGO:00511712510.038
regulation of cellular ketone metabolic processGO:001056570.038
larval developmentGO:000216420.037
action potentialGO:0001508190.037
complement activationGO:000695630.037
lymphocyte mediated immunityGO:000244950.037
ear morphogenesisGO:0042471640.037
carbon dioxide transportGO:001567030.037
cell death in response to oxidative stressGO:003647320.037
response to biotic stimulusGO:0009607970.037
negative regulation of programmed cell deathGO:0043069580.036
regulation of immune responseGO:0050776140.036
organic anion transportGO:0015711150.036
Zebrafish Mouse
blood vessel morphogenesisGO:00485142160.036
myelin assemblyGO:003228810.035
i kappab kinase nf kappab signalingGO:000724940.035
membrane repolarizationGO:008600920.035
rna metabolic processGO:00160702190.034
maintenance of locationGO:005123540.034
rna biosynthetic processGO:00327741810.034
cytosolic calcium ion transportGO:006040130.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
epidermal cell fate specificationGO:000995740.032
response to hexoseGO:000974630.032
regulation of biosynthetic processGO:00098892500.032
regulation of response to biotic stimulusGO:000283120.032
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.032
hydrogen peroxide metabolic processGO:004274320.032
regulation of i kappab kinase nf kappab signalingGO:004312240.032
cellular response to hormone stimulusGO:0032870390.032
sodium ion transmembrane transportGO:0035725210.031
Zebrafish
autophagyGO:000691440.031
cellular nitrogen compound metabolic processGO:00346412900.031
embryonic organ morphogenesisGO:00485622740.031
single organism localizationGO:19025782250.031
Zebrafish Mouse Worm
axon ensheathment in central nervous systemGO:003229120.031
response to lipidGO:0033993600.031
response to organic substanceGO:00100331530.031
sulfate transmembrane transportGO:190235820.031
sympathetic nervous system developmentGO:004848530.030
agingGO:000756820.030
protein secretionGO:000930610.030
b cell mediated immunityGO:001972430.030
heterocycle biosynthetic processGO:00181302150.029
localization of cellGO:00516742440.029
calcium ion transport into cytosolGO:006040230.029
iron ion homeostasisGO:005507240.029
cellular nitrogen compound biosynthetic processGO:00442712180.028
central nervous system neuron axonogenesisGO:0021955180.028
response to hormoneGO:0009725480.028
angiogenesisGO:00015251580.028
lymphocyte proliferationGO:004665110.028
negative regulation of defense responseGO:003134820.028
regulation of sequestering of calcium ionGO:005128240.027
central nervous system myelinationGO:002201020.027
cell motilityGO:00488702440.027
innate immune response activating signal transductionGO:000275850.027
regulation of production of molecular mediator of immune responseGO:000270010.027
fatty acid transportGO:001590810.026
positive regulation of i kappab kinase nf kappab signalingGO:004312330.026
regulation of macromolecule biosynthetic processGO:00105562250.026
regulation of rna metabolic processGO:00512522240.026
regulation of cellular component movementGO:0051270550.026
response to endogenous stimulusGO:0009719830.026
cellular macromolecule metabolic processGO:00442603910.026
response to other organismGO:0051707970.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.026
macromolecule biosynthetic processGO:00090592270.026
inorganic cation transmembrane transportGO:0098662500.026
Zebrafish
response to glucocorticoidGO:005138410.026
ameboidal type cell migrationGO:00016671430.026
adult behaviorGO:003053420.025
regulation of protein modification by small protein conjugation or removalGO:190332030.025
regulation of cellular amine metabolic processGO:003323800.025
membrane fusionGO:006102520.025
positive regulation of cytosolic calcium ion concentrationGO:000720440.025
transmission of nerve impulseGO:0019226190.025
stem cell maintenanceGO:001982740.025
purine nucleoside monophosphate catabolic processGO:000912840.024
negative regulation of protein phosphorylationGO:000193340.024
single organism biosynthetic processGO:0044711710.024
myeloid cell developmentGO:0061515320.024
aromatic compound biosynthetic processGO:00194382170.024
organelle fusionGO:004828430.024
cellular response to chemical stimulusGO:00708871570.024
regulation of rna biosynthetic processGO:20011412130.024
positive regulation of jun kinase activityGO:004350720.024
carboxylic acid metabolic processGO:0019752220.024
signal transductionGO:00071654550.024
cellular amine metabolic processGO:004410620.023
lateral line system developmentGO:0048925760.023
regulation of cellular carbohydrate metabolic processGO:001067540.023
morphogenesis of an epitheliumGO:00020093330.023
negative regulation of nitrogen compound metabolic processGO:0051172590.023
nucleoside monophosphate catabolic processGO:000912540.023
response to woundingGO:00096111160.023
hypotonic salinity responseGO:004253950.023
response to exogenous dsrnaGO:004333060.023
cellular component movementGO:00069283350.022
heterocycle metabolic processGO:00464832900.022
single organism transportGO:00447652060.022
Zebrafish Mouse Worm
positive regulation of cellular amino acid metabolic processGO:004576400.022
single organism metabolic processGO:00447102170.022
central nervous system neuron developmentGO:0021954290.022
response to external biotic stimulusGO:0043207970.022
eye developmentGO:00016542770.021
nucleic acid templated transcriptionGO:00976591810.021
nucleobase containing compound metabolic processGO:00061392740.021
mitochondrion organizationGO:000700540.021
regulation of cell deathGO:00109411030.021
cellular carbohydrate metabolic processGO:004426240.021
transportGO:00068102200.021
Zebrafish Mouse Worm
regulation of cellular amino acid metabolic processGO:000652100.021
oxoacid metabolic processGO:0043436310.021
hatching gland developmentGO:004878530.021
regulation of protein complex assemblyGO:004325430.021
cellular component biogenesisGO:00440851780.020
stem cell proliferationGO:007208940.020
regulation of glucose importGO:004632410.020
multi organism processGO:00517041340.020
protein metabolic processGO:00195381830.020
locomotionGO:00400113130.020
calcium ion homeostasisGO:0055074190.020
cellular response to organic substanceGO:00713101050.020
nuclear transportGO:005116940.020
gene expressionGO:00104672520.020
response to glucoseGO:000974930.020
fatty acid biosynthetic processGO:000663340.019
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.019
negative regulation of cell migrationGO:0030336170.019
establishment of protein localization to organelleGO:007259440.019
multicellular organism growthGO:003526440.019
Worm
cellular response to drugGO:003569010.019
brain developmentGO:00074202930.019
chemical homeostasisGO:0048878490.019
central nervous system myelin formationGO:003228910.019
gas transportGO:001566930.019
cell surface receptor signaling pathwayGO:00071663250.019
monovalent inorganic anion homeostasisGO:005508360.019
endosomal transportGO:001619720.018
regulation of intracellular signal transductionGO:1902531570.018
renal absorptionGO:007029310.018
hypotonic responseGO:000697150.018
skeletal system developmentGO:00015011810.018
ammonium transmembrane transportGO:007248820.018
antimicrobial humoral responseGO:001973020.018
connective tissue developmentGO:0061448990.018
positive regulation of cell adhesionGO:004578510.018
single organism membrane fusionGO:004480120.018
cranial ganglion developmentGO:006155030.018
cellular protein catabolic processGO:004425740.018
cellular component disassemblyGO:002241110.018
transcription dna templatedGO:00063511810.018
regulation of cell communicationGO:00106462320.018
Worm
negative regulation of protein kinase activityGO:000646940.018
retina morphogenesis in camera type eyeGO:0060042790.017
positive regulation of jnk cascadeGO:004633030.017
developmental pigmentationGO:0048066480.017
urea transportGO:0015840110.017
response to corticosteroidGO:003196010.017
negative regulation of macromolecule metabolic processGO:0010605760.017
negative regulation of cell deathGO:0060548600.017
regulation of bindingGO:005109830.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
response to nitrogen compoundGO:1901698190.017
positive regulation of lymphocyte mediated immunityGO:000270810.017
positive regulation of cellular catabolic processGO:003133130.017
erythrocyte developmentGO:0048821240.017
positive regulation of lipid metabolic processGO:004583410.017
nerve developmentGO:0021675450.017
reactive nitrogen species metabolic processGO:200105700.016
negative regulation of apoptotic processGO:0043066550.016
regulation of tube sizeGO:003515020.016
negative regulation of kinase activityGO:003367340.016
cellular biosynthetic processGO:00442492860.016
response to oxygen containing compoundGO:1901700550.016
ribonucleoside monophosphate catabolic processGO:000915840.016
cellular response to decreased oxygen levelsGO:003629410.016
regulation of metal ion transportGO:001095940.016
cellular response to external stimulusGO:007149620.016
lipid catabolic processGO:001604240.016
g protein coupled receptor signaling pathwayGO:0007186740.016
organelle organizationGO:00069962270.016
atp catabolic processGO:000620040.016
antibiotic transportGO:004289120.015
Zebrafish
organic acid metabolic processGO:0006082310.015
carbohydrate biosynthetic processGO:001605110.015
metal ion homeostasisGO:0055065260.015
blood circulationGO:0008015870.015
renal system developmentGO:0072001940.015
negative regulation of metabolic processGO:0009892860.015
cellular response to biotic stimulusGO:007121630.015
regulation of blood vessel sizeGO:005088020.015
regulation of protein catabolic processGO:004217610.015
regulation of glucose transportGO:001082710.015
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.015
chordate embryonic developmentGO:00430092710.014
response to molecule of bacterial originGO:0002237140.014
otic vesicle developmentGO:0071599420.014
pigment cell differentiationGO:0050931380.014
neurological system processGO:0050877620.014
toll like receptor signaling pathwayGO:000222440.014
myelinationGO:0042552180.014
cellular component assemblyGO:00226071700.014
protein localization to nucleusGO:003450430.014
brain morphogenesisGO:0048854180.014
phosphatidylinositol mediated signalingGO:004801520.014
protein acetylationGO:000647320.014
cartilage developmentGO:0051216960.014
positive regulation of protein kinase b signalingGO:005189710.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
positive regulation of immune system processGO:0002684170.014
nuclear importGO:005117030.014
embryonic hemopoiesisGO:0035162530.014
Zebrafish
calcium ion importGO:007050940.014
protein stabilizationGO:005082120.014
somatic muscle developmentGO:000752540.013
cellular protein modification processGO:00064641000.013
regulation of signal transductionGO:00099662250.013
central nervous system neuron differentiationGO:0021953740.013
positive regulation of immune responseGO:0050778110.013
protein heterooligomerizationGO:005129110.013
small molecule catabolic processGO:004428230.013
kidney developmentGO:0001822920.013
nucleobase containing compound biosynthetic processGO:00346542050.013
negative regulation of biological processGO:00485193040.013
regulation of gene expressionGO:00104682650.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
regulation of endothelial cell proliferationGO:000193610.013
regulation of protein transportGO:005122330.013
multicellular organismal homeostasisGO:0048871290.013
lateral line ganglion developmentGO:004889020.013
protein targeting to nucleusGO:004474430.013
ph reductionGO:004585110.013
inner ear morphogenesisGO:0042472630.013
production of molecular mediator of immune responseGO:000244020.013
neuronal action potentialGO:0019228180.013
regulation of protein ubiquitinationGO:003139630.013
positive regulation of epithelial cell differentiationGO:003085820.013
central nervous system developmentGO:00074173870.013
organic cyclic compound metabolic processGO:19013603010.013
sensory organ morphogenesisGO:00905962000.013
lymphocyte homeostasisGO:000226010.013
regulation of intracellular phGO:005145310.013
enteric nervous system developmentGO:0048484120.012
entrainment of circadian clockGO:000964920.012
intracellular signal transductionGO:0035556850.012
positive regulation of response to stimulusGO:0048584800.012
response to bacteriumGO:0009617580.012
cellular response to xenobiotic stimulusGO:0071466350.012
regulation of carbohydrate metabolic processGO:000610940.012
single organism nuclear importGO:190259330.012
multi organism cellular processGO:004476420.012
positive regulation of cell activationGO:005086710.012
embryonic skeletal system morphogenesisGO:0048704930.012
oxalate transportGO:001953210.012
regulation of dendrite developmentGO:005077330.012
negative regulation of catabolic processGO:000989530.012
lateral line nerve developmentGO:004889290.012
positive regulation of cytokine productionGO:000181920.012
immunoglobulin productionGO:000237710.012
regulation of carbohydrate biosynthetic processGO:004325510.012
anion transmembrane transportGO:0098656120.012
Worm
tissue remodelingGO:004877140.012
regulation of multicellular organismal developmentGO:20000262230.012
negative regulation of mapk cascadeGO:004340940.012
peripheral nervous system developmentGO:0007422550.012
negative regulation of signal transduction in absence of ligandGO:190109910.012
stem cell developmentGO:0048864820.012
negative regulation of map kinase activityGO:004340720.012
ion homeostasisGO:0050801410.012
defense responseGO:0006952470.012
single organism organelle organizationGO:19025891990.012
cellular aromatic compound metabolic processGO:00067252950.012
osteoclast developmentGO:003603510.012
axon ensheathmentGO:0008366180.011
positive regulation of glucose transportGO:001082810.011
protein importGO:001703830.011
autonomic nervous system developmentGO:0048483190.011
fatty acid elongation unsaturated fatty acidGO:001936810.011
organic cyclic compound biosynthetic processGO:19013622230.011
glucose importGO:004632320.011
glial cell differentiationGO:0010001420.011
response to uvGO:000941130.011
regulation of cellular response to oxidative stressGO:190040720.011
regulation of response to cytokine stimulusGO:006075930.011
negative regulation of rna metabolic processGO:0051253480.011
positive regulation of cellular processGO:00485222010.011
multicellular organismal macromolecule metabolic processGO:004425920.011
smooth muscle contractionGO:000693920.011
regulation of macromolecule metabolic processGO:00602553170.011
humoral immune responseGO:000695950.011
regulation of cytokine mediated signaling pathwayGO:000195930.011
negative regulation of protein transportGO:005122430.011
regulation of actin filament based movementGO:190311510.011
gtp metabolic processGO:004603940.011
long chain fatty acid transportGO:001590910.011
amine metabolic processGO:000930820.011
erk1 and erk2 cascadeGO:007037140.011
positive regulation of multicellular organismal processGO:0051240520.010
Worm
phosphorylationGO:0016310690.010
regulation of response to oxidative stressGO:190288220.010
negative regulation of multi organism processGO:004390130.010
positive regulation of cellular amine metabolic processGO:003324000.010
retina development in camera type eyeGO:00600411460.010
carbohydrate homeostasisGO:003350010.010
regulation of lipid transportGO:003236840.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
positive regulation of epithelial cell proliferationGO:005067910.010
negative regulation of secretion by cellGO:190353120.010
nucleocytoplasmic transportGO:000691340.010

slc4a4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.056
inherited metabolic disorderDOID:65500.056
immune system diseaseDOID:291400.013
disease of anatomical entityDOID:700.013
lysosomal storage diseaseDOID:321100.013
nervous system diseaseDOID:86300.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011