Danio rerio

77 known processes

bhlhe40

basic helix-loop-helix family, member e40

(Aliases: bhlhb2,zgc:76913,wu:fm54h07,DEC1,wu:fc28a06)

bhlhe40 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hepaticobiliary system developmentGO:0061008980.694
agingGO:000756820.675
nitrogen compound metabolic processGO:00068073190.414
liver developmentGO:0001889960.363
lipid storageGO:001991510.354
determination of left right symmetryGO:00073681790.337
embryonic organ developmentGO:00485683810.315
embryonic heart tube morphogenesisGO:00031431080.313
positive regulation of biological processGO:00485182530.296
specification of symmetryGO:00097992040.290
locomotionGO:00400113130.285
heterocycle metabolic processGO:00464832900.282
regulation of biological qualityGO:00650082630.268
Rat
regulation of developmental processGO:00507932470.234
heart loopingGO:0001947940.232
determination of heart left right asymmetryGO:00613711170.229
cartilage developmentGO:0051216960.227
cellular nitrogen compound metabolic processGO:00346412900.219
regulation of metabolic processGO:00192223590.217
regulation of multicellular organismal processGO:00512392770.209
aromatic compound biosynthetic processGO:00194382170.207
circadian regulation of gene expressionGO:003292280.200
regulation of blood pressureGO:000821710.200
epithelial tube morphogenesisGO:00605621480.198
cellular nitrogen compound biosynthetic processGO:00442712180.192
cellular response to extracellular stimulusGO:003166820.184
organic cyclic compound metabolic processGO:19013603010.182
oxoacid metabolic processGO:0043436310.175
regulation of signalingGO:00230512350.172
Rat
cell proliferationGO:0008283800.171
regulation of transcription dna templatedGO:00063552130.168
positive regulation of cell activationGO:005086710.163
organic substance biosynthetic processGO:19015762890.160
maintenance of locationGO:005123540.160
cellular response to external stimulusGO:007149620.159
larval developmentGO:000216420.157
biosynthetic processGO:00090582940.154
immune system processGO:00023762410.152
regulation of response to stimulusGO:00485832690.151
organelle assemblyGO:00709251100.136
signal transductionGO:00071654550.132
positive regulation of cytokine productionGO:000181920.129
organic cyclic compound biosynthetic processGO:19013622230.127
growthGO:00400071740.126
primitive erythrocyte differentiationGO:006031950.125
phagocytosis engulfmentGO:000691110.123
regulation of endocrine processGO:004406020.123
cellular macromolecule biosynthetic processGO:00346452240.121
single organism metabolic processGO:00447102170.117
regulation of cellular macromolecule biosynthetic processGO:20001122220.117
nucleobase containing compound metabolic processGO:00061392740.116
hemopoiesisGO:00300971830.110
regulation of i kappab kinase nf kappab signalingGO:004312240.108
cellular response to nutrient levelsGO:003166920.105
intracellular receptor signaling pathwayGO:0030522300.103
positive regulation of cellular processGO:00485222010.102
heart morphogenesisGO:00030071560.102
regulation of circadian rhythmGO:004275240.102
Mouse Rat
carboxylic acid metabolic processGO:0019752220.101
cellular response to starvationGO:000926710.092
lipid metabolic processGO:0006629520.092
nucleobase containing compound biosynthetic processGO:00346542050.089
skeletal system developmentGO:00015011810.088
homeostatic processGO:00425921420.088
deathGO:00162651210.087
positive regulation of muscle tissue developmentGO:190186310.087
response to bacteriumGO:0009617580.085
nucleic acid templated transcriptionGO:00976591810.085
fin regenerationGO:0031101510.084
blood circulationGO:0008015870.083
positive regulation of transportGO:005105020.082
regulation of nucleic acid templated transcriptionGO:19035062130.082
positive regulation of translationGO:004572710.081
heterocycle biosynthetic processGO:00181302150.081
muscle structure developmentGO:00610611960.081
small molecule metabolic processGO:0044281770.080
system processGO:00030081850.080
positive regulation of striated muscle cell differentiationGO:005115510.078
response to other organismGO:0051707970.074
multicellular organismal metabolic processGO:004423620.073
cellular biosynthetic processGO:00442492860.073
regulation of cytokine productionGO:000181730.071
i kappab kinase nf kappab signalingGO:000724940.070
negative regulation of gene expressionGO:0010629650.069
organic acid metabolic processGO:0006082310.068
response to woundingGO:00096111160.067
digestive tract developmentGO:00485652650.067
response to nutrientGO:000758430.066
regulation of heart growthGO:006042020.065
response to decreased oxygen levelsGO:0036293250.064
negative regulation of biological processGO:00485193040.064
regulation of autophagyGO:001050630.062
embryonic organ morphogenesisGO:00485622740.062
regulation of signal transductionGO:00099662250.061
transportGO:00068102200.060
diencephalon developmentGO:0021536580.060
response to external stimulusGO:00096052640.059
Mouse Rat
regulation of transcription from rna polymerase ii promoterGO:00063571140.058
Human Mouse Rat
single organism transportGO:00447652060.058
heart developmentGO:00075073130.057
chordate embryonic developmentGO:00430092710.056
cellular component assembly involved in morphogenesisGO:00109271070.056
response to hexoseGO:000974630.056
negative regulation of protein kinase activityGO:000646940.055
endocrine processGO:005088620.055
transcription dna templatedGO:00063511810.055
regulation of gene expressionGO:00104682650.054
hormone transportGO:000991420.054
innervationGO:006038430.054
regulation of biosynthetic processGO:00098892500.053
response to biotic stimulusGO:0009607970.052
regulation of glial cell differentiationGO:004568540.052
regulation of cellular biosynthetic processGO:00313262450.050
transcription from rna polymerase ii promoterGO:0006366800.050
Human Mouse Rat
phosphate containing compound metabolic processGO:00067961080.050
regulation of multicellular organism growthGO:004001440.049
single organism localizationGO:19025782250.049
regulation of nitrogen compound metabolic processGO:00511712510.047
protein importGO:001703830.047
apoptotic processGO:00069151160.047
positive regulation of striated muscle tissue developmentGO:004584410.047
lateral mesoderm developmentGO:0048368230.047
nucleic acid metabolic processGO:00903042440.047
regulation of tube sizeGO:003515020.046
response to hypoxiaGO:0001666250.046
developmental growthGO:00485891660.046
response to organic cyclic compoundGO:0014070510.045
brain developmentGO:00074202930.045
positive regulation of muscle cell differentiationGO:005114910.045
vasculature developmentGO:00019442780.045
cellular response to organic substanceGO:00713101050.045
mesoderm developmentGO:0007498880.044
regulation of localizationGO:00328791040.044
regulation of cell deathGO:00109411030.043
regulation of cell communicationGO:00106462320.042
Rat
response to nutrient levelsGO:0031667100.042
synaptic growth at neuromuscular junctionGO:005112420.042
organonitrogen compound metabolic processGO:1901564740.041
localization of cellGO:00516742440.041
regulation of growthGO:0040008420.041
regulation of cardiac muscle tissue developmentGO:005502410.041
regulation of macromolecule biosynthetic processGO:00105562250.040
regulation of rna biosynthetic processGO:20011412130.040
immune system developmentGO:00025201910.040
oxidation reduction processGO:0055114410.040
regulation of macromolecule metabolic processGO:00602553170.039
toll like receptor signaling pathwayGO:000222440.039
amine metabolic processGO:000930820.039
tissue remodelingGO:004877140.038
cell surface receptor signaling pathwayGO:00071663250.038
programmed cell deathGO:00125011190.037
negative regulation of kinase activityGO:003367340.037
cellular amino acid metabolic processGO:000652070.036
response to stressGO:00069502630.036
smooth muscle contractionGO:000693920.036
positive regulation of immune system processGO:0002684170.036
regulation of systemic arterial blood pressureGO:000307310.035
somitogenesisGO:0001756870.035
mononuclear cell proliferationGO:003294310.035
cellular amide metabolic processGO:004360340.033
regulation of multicellular organismal developmentGO:20000262230.033
blood vessel developmentGO:00015682460.033
determination of bilateral symmetryGO:00098552040.032
nuclear transportGO:005116940.032
phagocytosisGO:000690930.032
eye developmentGO:00016542770.032
cellular carbohydrate metabolic processGO:004426240.032
erythrocyte homeostasisGO:0034101550.032
positive regulation of immune effector processGO:000269930.032
positive regulation of nitrogen compound metabolic processGO:0051173690.031
response to external biotic stimulusGO:0043207970.031
macromolecule biosynthetic processGO:00090592270.030
protein secretionGO:000930610.030
regulation of inflammatory responseGO:005072720.030
leukocyte proliferationGO:007066110.030
head developmentGO:00603223030.030
response to temperature stimulusGO:0009266150.029
positive regulation of cellular biosynthetic processGO:0031328680.029
muscle organ developmentGO:00075171010.029
specification of organ identityGO:001009220.028
endocardial cushion formationGO:000327220.028
circulatory system processGO:0003013870.028
positive regulation of rna biosynthetic processGO:1902680570.028
regionalizationGO:00030022740.028
multicellular organism growthGO:003526440.028
muscle cell differentiationGO:00426921390.028
proteolysis involved in cellular protein catabolic processGO:005160330.027
neuron differentiationGO:00301823530.027
positive regulation of defense responseGO:003134990.027
zymogen activationGO:003163830.027
multicellular organismal homeostasisGO:0048871290.027
hormone secretionGO:004687920.027
myeloid cell differentiationGO:0030099860.026
generation of neuronsGO:00486993850.026
response to endogenous stimulusGO:0009719830.026
response to drugGO:004249330.026
membrane invaginationGO:001032410.026
regulation of cell differentiationGO:00455951420.026
hindbrain developmentGO:0030902910.026
cell migrationGO:00164772370.025
cellular aromatic compound metabolic processGO:00067252950.025
aorta developmentGO:003590440.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
cellular response to oxygen levelsGO:007145310.025
membrane repolarizationGO:008600920.024
cellular amine metabolic processGO:004410620.024
establishment of protein localization to organelleGO:007259440.024
protein targeting to nucleusGO:004474430.024
primitive hemopoiesisGO:0060215270.024
negative regulation of secretion by cellGO:190353120.023
defense responseGO:0006952470.023
regulation of carbohydrate metabolic processGO:000610940.023
positive regulation of cellular metabolic processGO:0031325940.023
response to oxygen levelsGO:0070482250.023
regulation of primary metabolic processGO:00800903110.023
striated muscle tissue developmentGO:00147061100.023
lipid localizationGO:0010876110.023
regulation of system processGO:0044057400.023
cellular response to lipidGO:0071396390.023
negative regulation of metabolic processGO:0009892860.023
regulation of programmed cell deathGO:00430671010.023
regulation of blood vessel sizeGO:005088020.022
regulation of blood circulationGO:1903522320.022
regulation of defense responseGO:0031347140.022
regulation of hormone levelsGO:0010817210.022
ectodermal cell fate specificationGO:000171520.022
negative regulation of protein serine threonine kinase activityGO:007190120.022
positive regulation of metabolic processGO:00098931080.022
regulation of protein metabolic processGO:0051246560.022
negative regulation of cell differentiationGO:0045596460.022
positive regulation of cell deathGO:0010942290.022
cellular response to biotic stimulusGO:007121630.022
tissue regenerationGO:0042246740.022
embryonic skeletal joint morphogenesisGO:006027230.022
negative regulation of cell deathGO:0060548600.022
embryo development ending in birth or egg hatchingGO:00097922710.021
digestive system developmentGO:00551232890.021
regulation of striated muscle tissue developmentGO:001620260.021
positive regulation of blood circulationGO:190352420.021
bmp signaling pathwayGO:0030509520.021
regulation of collagen metabolic processGO:001071220.021
regulation of response to biotic stimulusGO:000283120.021
negative regulation of cellular processGO:00485232830.021
response to alkaloidGO:004327920.021
mesenchyme developmentGO:00604851270.021
regulation of cell activationGO:005086510.021
rna metabolic processGO:00160702190.021
response to chemicalGO:00422213200.021
single organism organelle organizationGO:19025891990.020
rna biosynthetic processGO:00327741810.020
multi organism processGO:00517041340.020
regulation of cellular carbohydrate metabolic processGO:001067540.020
cellular protein catabolic processGO:004425740.020
cellular protein metabolic processGO:00442671290.020
pancreas developmentGO:0031016840.020
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.020
regenerationGO:0031099910.020
single organism biosynthetic processGO:0044711710.020
response to extracellular stimulusGO:0009991100.020
embryonic heart tube developmentGO:00350501330.020
camera type eye developmentGO:00430102220.019
central nervous system developmentGO:00074173870.019
cellular response to chemical stimulusGO:00708871570.019
positive regulation of cell cycleGO:004578730.019
single organism carbohydrate metabolic processGO:0044723120.019
regulation of cellular component organizationGO:0051128860.019
g1 s transition of mitotic cell cycleGO:000008210.019
regulation of dna templated transcription in response to stressGO:004362000.019
negative regulation of signal transductionGO:0009968940.019
positive regulation of response to external stimulusGO:003210390.019
collagen metabolic processGO:003296320.019
cell motilityGO:00488702440.019
response to corticosteroidGO:003196010.018
cell deathGO:00082191210.018
cation transportGO:0006812810.018
connective tissue developmentGO:0061448990.018
lipid homeostasisGO:005508830.018
determination of left right asymmetry in lateral mesodermGO:0003140200.018
negative regulation of cellular metabolic processGO:0031324770.018
positive regulation of innate immune responseGO:004508980.017
cellular response to decreased oxygen levelsGO:003629410.017
regulation of rna metabolic processGO:00512522240.017
angiogenesisGO:00015251580.017
organelle organizationGO:00069962270.017
organonitrogen compound biosynthetic processGO:1901566470.017
protein metabolic processGO:00195381830.017
single organism nuclear importGO:190259330.017
monocarboxylic acid metabolic processGO:0032787170.017
morphogenesis of an epitheliumGO:00020093330.017
eye photoreceptor cell developmentGO:0042462300.017
dorsal ventral pattern formationGO:00099531250.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
hindbrain morphogenesisGO:0021575220.016
positive regulation of cellular amine metabolic processGO:003324000.016
negative regulation of cell communicationGO:0010648960.016
cellular component disassemblyGO:002241110.016
regulation of organ growthGO:004662030.016
gene expressionGO:00104672520.016
cellular macromolecule metabolic processGO:00442603910.016
negative regulation of blood circulationGO:190352320.016
positive regulation of cellular component biogenesisGO:004408930.016
immune response activating signal transductionGO:000275750.016
wound healingGO:0042060900.016
cellular response to lipopolysaccharideGO:007122230.016
chemical homeostasisGO:0048878490.016
cellular component morphogenesisGO:00329893360.016
retina development in camera type eyeGO:00600411460.016
lymphocyte proliferationGO:004665110.016
regulation of anatomical structure sizeGO:0090066330.015
negative regulation of mesodermal cell fate specificationGO:004266230.015
positive regulation of secretion by cellGO:190353210.015
cell cycle g1 s phase transitionGO:004484310.015
ectodermal cell differentiationGO:001066820.015
regulation of muscle tissue developmentGO:190186160.015
insulin like growth factor receptor signaling pathwayGO:004800940.015
positive regulation of cell communicationGO:0010647560.015
autophagyGO:000691440.015
response to acid chemicalGO:0001101170.015
b cell activationGO:004211320.015
peptide transportGO:001583310.015
cerebellar granular layer developmentGO:002168130.015
skeletal muscle organ developmentGO:0060538780.015
carbohydrate metabolic processGO:0005975120.015
immune effector processGO:0002252230.015
negative regulation of map kinase activityGO:004340720.015
endocardial cushion developmentGO:000319760.015
mitochondrion organizationGO:000700540.015
neuron projection guidanceGO:0097485860.015
negative regulation of mitosisGO:004583930.015
cellular protein modification processGO:00064641000.015
proteasomal protein catabolic processGO:001049820.015
response to organic substanceGO:00100331530.015
sensory organ developmentGO:00074233930.014
cell substrate adhesionGO:003158940.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
cation transmembrane transportGO:0098655650.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.014
protein stabilizationGO:005082120.014
carbohydrate derivative metabolic processGO:1901135610.014
septum transversum developmentGO:000334340.014
endocardial cushion morphogenesisGO:000320330.014
cardiac chamber formationGO:000320740.014
positive regulation of multicellular organismal processGO:0051240520.014
positive regulation of gliogenesisGO:001401520.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
common bile duct developmentGO:0061009130.014
negative regulation of dna metabolic processGO:005105340.014
nuclear importGO:005117030.014
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.014
cellular response to hypoxiaGO:007145610.013
interspecies interaction between organismsGO:004441940.013
cellular component movementGO:00069283350.013
positive regulation of nucleic acid templated transcriptionGO:1903508570.013
positive regulation of signal transductionGO:0009967560.013
negative regulation of protein phosphorylationGO:000193340.013
wnt signaling pathwayGO:0016055800.013
macromolecular complex assemblyGO:0065003350.013
positive regulation of leukocyte mediated immunityGO:000270510.013
response to monosaccharideGO:003428430.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
regulation of hormone secretionGO:004688320.013
positive regulation of cellular catabolic processGO:003133130.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
regulation of cytoplasmic transportGO:190364940.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.012
erythrocyte differentiationGO:0030218540.012
lateral inhibitionGO:004633110.012
carbohydrate homeostasisGO:003350010.012
hormone biosynthetic processGO:004244630.012
heart growthGO:006041970.012
gland developmentGO:00487321430.012
multi organism cellular processGO:004476420.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
response to vitaminGO:003327330.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
regulation of cellular metabolic processGO:00313233200.012
regulation of apoptotic processGO:0042981980.012
fin developmentGO:0033333770.012
negative regulation of epithelial cell proliferationGO:005068010.012
negative regulation of cytokine productionGO:000181810.012
regulation of establishment of protein localizationGO:007020140.012
response to inorganic substanceGO:0010035380.012
protein import into nucleusGO:000660630.012
response to glucoseGO:000974930.012
multicellular organismal macromolecule metabolic processGO:004425920.012
regulation of cellular ketone metabolic processGO:001056570.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
kupffer s vesicle developmentGO:0070121500.011
regulation of intracellular signal transductionGO:1902531570.011
negative regulation of response to stimulusGO:00485851040.011
collagen biosynthetic processGO:003296420.011
nucleocytoplasmic transportGO:000691340.011
modification of morphology or physiology of other organismGO:003582140.011
regulation of neural precursor cell proliferationGO:200017730.011
cell killingGO:000190620.011
regulation of cellular amine metabolic processGO:003323800.011
ion transportGO:00068111140.011
neuron developmentGO:00486662620.011
amide biosynthetic processGO:004360410.011
lipid biosynthetic processGO:0008610220.011
embryonic skeletal system developmentGO:0048706970.011
branched chain amino acid metabolic processGO:000908110.011
regulation of molecular functionGO:0065009700.011
Human
regulation of multicellular organismal metabolic processGO:004424620.011
cell agingGO:000756920.011
protein localization to nucleusGO:003450430.011
negative regulation of mapk cascadeGO:004340940.011
determination of liver left right asymmetryGO:0071910110.011
ph reductionGO:004585110.011
viral processGO:001603210.011
response to metal ionGO:0010038340.010
transmembrane transportGO:00550851200.010
hemostasisGO:0007599130.010
renal system process involved in regulation of blood volumeGO:000197710.010
negative regulation of protein transportGO:005122430.010
positive regulation of nuclease activityGO:003207510.010
odontogenesis of dentin containing toothGO:004247510.010
inner ear developmentGO:00488391260.010
intracellular signal transductionGO:0035556850.010
photoreceptor cell fate commitmentGO:004655210.010
cardiac atrium developmentGO:000323040.010
regulation of cell migrationGO:0030334400.010

bhlhe40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.067
disease of anatomical entityDOID:700.037
inherited metabolic disorderDOID:65500.026
cardiovascular system diseaseDOID:128700.020
organ system cancerDOID:005068600.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
musculoskeletal system diseaseDOID:1700.013
connective tissue diseaseDOID:6500.013