Danio rerio

13 known processes

lrp2

low density lipoprotein-related protein 2

(Aliases: im:680590)

lrp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronephros developmentGO:0048793690.792
cilium morphogenesisGO:0060271850.660
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.567
chemotaxisGO:00069351040.492
renal system developmentGO:0072001940.486
cellular component morphogenesisGO:00329893360.472
camera type eye developmentGO:00430102220.462
central nervous system developmentGO:00074173870.436
taxisGO:00423301090.416
swim bladder developmentGO:0048794190.398
urogenital system developmentGO:0001655970.394
cell part morphogenesisGO:00329902460.388
organic cyclic compound metabolic processGO:19013603010.371
cell projection organizationGO:00300302840.370
eye developmentGO:00016542770.354
sensory organ morphogenesisGO:00905962000.350
cell projection morphogenesisGO:00488582440.324
canonical wnt signaling pathwayGO:0060070480.315
embryonic organ morphogenesisGO:00485622740.292
kidney developmentGO:0001822920.285
cell projection assemblyGO:0030031640.281
mesoderm morphogenesisGO:0048332510.261
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.256
regulation of signalingGO:00230512350.249
renal filtrationGO:0097205100.249
neural tube patterningGO:0021532330.248
pigmentationGO:0043473850.226
axon guidanceGO:0007411860.222
somitogenesisGO:0001756870.221
regulation of response to stimulusGO:00485832690.216
establishment or maintenance of bipolar cell polarityGO:0061245120.212
cellular component movementGO:00069283350.205
regulation of biological qualityGO:00650082630.200
glomerulus developmentGO:0032835270.197
negative regulation of wnt signaling pathwayGO:0030178300.181
regulation of metabolic processGO:00192223590.177
segmentationGO:0035282970.166
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.166
regulation of cell communicationGO:00106462320.165
neuron differentiationGO:00301823530.164
somite developmentGO:0061053960.155
chordate embryonic developmentGO:00430092710.145
wnt signaling pathwayGO:0016055800.137
heart loopingGO:0001947940.132
growthGO:00400071740.120
synaptic transmission cholinergicGO:000727140.118
mitotic cell cycleGO:0000278640.118
carbohydrate derivative metabolic processGO:1901135610.114
cell cycle processGO:0022402530.109
nucleoside monophosphate catabolic processGO:000912540.108
sensory organ developmentGO:00074233930.108
retinal ganglion cell axon guidanceGO:0031290350.107
endoderm developmentGO:0007492490.106
retina development in camera type eyeGO:00600411460.105
cytoskeleton organizationGO:0007010960.102
establishment or maintenance of cell polarityGO:0007163290.101
response to chemicalGO:00422213200.101
fin developmentGO:0033333770.101
negative regulation of cellular processGO:00485232830.096
signal transductionGO:00071654550.095
cilium assemblyGO:0042384580.093
retina morphogenesis in camera type eyeGO:0060042790.091
epithelial cell differentiationGO:00308551160.090
cell morphogenesis involved in differentiationGO:00009041950.087
system processGO:00030081850.085
myelinationGO:0042552180.085
negative regulation of canonical wnt signaling pathwayGO:0090090210.083
response to drugGO:004249330.082
generation of neuronsGO:00486993850.082
positive regulation of cell communicationGO:0010647560.081
negative regulation of cell communicationGO:0010648960.079
apical protein localizationGO:004517660.078
larval developmentGO:000216420.078
embryonic limb morphogenesisGO:003032620.077
organelle organizationGO:00069962270.074
organic anion transportGO:0015711150.071
ameboidal type cell migrationGO:00016671430.069
eye morphogenesisGO:00485921440.068
embryonic heart tube morphogenesisGO:00031431080.068
cilium organizationGO:0044782710.067
positive regulation of map kinase activityGO:004340630.066
regulation of peptidyl tyrosine phosphorylationGO:005073010.066
multicellular organism growthGO:003526440.064
immune system developmentGO:00025201910.064
regulation of purine nucleotide catabolic processGO:003312120.064
cell morphogenesis involved in neuron differentiationGO:00486671630.064
embryonic retina morphogenesis in camera type eyeGO:0060059220.064
mesoderm developmentGO:0007498880.064
regulation of neurotransmitter transportGO:005158810.063
embryonic eye morphogenesisGO:0048048300.062
cellular component assemblyGO:00226071700.062
organelle fissionGO:0048285230.059
developmental growthGO:00485891660.059
localization of cellGO:00516742440.059
epithelial cell morphogenesisGO:000338220.059
non canonical wnt signaling pathwayGO:0035567130.058
nonmotile primary cilium assemblyGO:003505820.058
regulation of signal transductionGO:00099662250.057
regulation of protein maturationGO:1903317100.057
guanosine containing compound catabolic processGO:190106920.057
regulation of canonical wnt signaling pathwayGO:0060828340.055
heart joggingGO:0003146400.054
regulation of wnt signaling pathwayGO:0030111530.053
negative regulation of response to stimulusGO:00485851040.052
homeostasis of number of cellsGO:0048872620.052
neural plate anterior posterior regionalizationGO:002199980.052
embryonic camera type eye developmentGO:0031076290.052
anterior posterior pattern specificationGO:00099521520.052
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.051
protein localizationGO:0008104400.050
maintenance of locationGO:005123540.048
homeostatic processGO:00425921420.047
ion transportGO:00068111140.047
nephron developmentGO:0072006310.047
cell substrate adhesionGO:003158940.046
leukocyte proliferationGO:007066110.046
programmed cell deathGO:00125011190.045
developmental programmed cell deathGO:001062340.045
single organism transportGO:00447652060.044
specification of symmetryGO:00097992040.044
positive regulation of cellular amino acid metabolic processGO:004576400.043
mitotic cell cycle processGO:1903047480.043
establishment or maintenance of apical basal cell polarityGO:0035088120.043
hindbrain developmentGO:0030902910.043
cell cycleGO:0007049930.043
cellular biosynthetic processGO:00442492860.042
negative regulation of cell cycle processGO:001094890.042
extrinsic apoptotic signaling pathwayGO:009719130.042
mesenchymal cell developmentGO:0014031780.041
single organism localizationGO:19025782250.041
regulation of organ morphogenesisGO:2000027350.041
neural crest cell differentiationGO:0014033720.040
reproductive processGO:0022414400.040
phagocytosisGO:000690930.040
protein metabolic processGO:00195381830.040
small molecule metabolic processGO:0044281770.040
neurological system processGO:0050877620.040
myeloid cell homeostasisGO:0002262560.040
regulation of cellular response to growth factor stimulusGO:0090287350.040
endocrine pancreas developmentGO:0031018270.039
mesodermal cell migrationGO:0008078120.039
microtubule based processGO:0007017600.039
stem cell differentiationGO:00488631170.039
anatomical structure homeostasisGO:0060249360.039
determination of bilateral symmetryGO:00098552040.039
renal system processGO:0003014140.038
lateral line system developmentGO:0048925760.038
ribonucleoside monophosphate catabolic processGO:000915840.038
response to external stimulusGO:00096052640.038
microtubule based movementGO:0007018330.038
single organism cell adhesionGO:0098602290.037
spindle assemblyGO:005122520.037
neuron developmentGO:00486662620.037
cell motilityGO:00488702440.037
female sex differentiationGO:004666040.037
cellular component assembly involved in morphogenesisGO:00109271070.037
microtubule organizing center organizationGO:003102310.036
lens development in camera type eyeGO:0002088220.036
primary neural tube formationGO:001402010.036
spermatid developmentGO:000728620.035
cellular response to external stimulusGO:007149620.035
organelle assemblyGO:00709251100.035
head developmentGO:00603223030.034
actin filament based movementGO:003004810.034
neuron migrationGO:0001764220.034
multicellular organismal signalingGO:0035637220.034
meiotic nuclear divisionGO:000712640.033
establishment of monopolar cell polarityGO:006116220.033
regulation of intracellular signal transductionGO:1902531570.033
nerve developmentGO:0021675450.033
regulation of multicellular organismal metabolic processGO:004424620.032
photoreceptor cell fate commitmentGO:004655210.032
positive regulation of cell substrate adhesionGO:001081110.032
regulation of multicellular organismal processGO:00512392770.032
gtp metabolic processGO:004603940.032
negative regulation of cellular metabolic processGO:0031324770.031
establishment of localizationGO:00512342440.031
macromolecule localizationGO:0033036540.031
guanosine containing compound metabolic processGO:190106840.031
astrocyte differentiationGO:004870810.030
brain developmentGO:00074202930.030
regulation of cellular component sizeGO:0032535300.030
pectoral fin morphogenesisGO:0035138290.030
cell morphogenesisGO:00009022890.029
axis elongationGO:0003401310.029
epithelial tube morphogenesisGO:00605621480.029
negative regulation of smoothened signaling pathwayGO:004587960.029
midbrain hindbrain boundary developmentGO:0030917230.029
regionalizationGO:00030022740.029
response to stressGO:00069502630.029
regulation of reproductive processGO:200024140.029
regulation of embryonic developmentGO:0045995470.028
mitotic dna integrity checkpointGO:004477440.028
auditory receptor cell fate commitmentGO:000991240.028
negative regulation of signal transductionGO:0009968940.028
hemopoiesisGO:00300971830.028
positive regulation of canonical wnt signaling pathwayGO:009026340.028
regulation of cellular ketone metabolic processGO:001056570.028
agingGO:000756820.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
microtubule cytoskeleton organizationGO:0000226330.028
glomerulus vasculature developmentGO:007201220.028
protein complex biogenesisGO:0070271300.028
regulation of epithelial to mesenchymal transitionGO:001071730.028
regulation of mitotic cell cycleGO:0007346250.027
mitotic nuclear divisionGO:0007067180.027
neuron projection morphogenesisGO:00488121610.027
cell adhesionGO:0007155400.027
cellular pigmentationGO:0033059300.027
heterocycle catabolic processGO:0046700150.027
single organism metabolic processGO:00447102170.027
regulation of nitrogen compound metabolic processGO:00511712510.027
digestive tract developmentGO:00485652650.027
mitotic dna damage checkpointGO:004477340.027
pronephric nephron tubule developmentGO:003902020.027
atp catabolic processGO:000620040.026
regulation of stem cell differentiationGO:200073640.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
anterior commissure morphogenesisGO:002196030.026
developmental pigmentationGO:0048066480.026
establishment of epithelial cell apical basal polarityGO:004519820.026
cellular localizationGO:0051641970.025
camera type eye morphogenesisGO:00485931080.025
positive regulation of protein polymerizationGO:003227320.025
nucleobase containing compound metabolic processGO:00061392740.025
rostrocaudal neural tube patterningGO:0021903290.025
centrosome cycleGO:000709810.025
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.025
forebrain regionalizationGO:002187140.025
neural crest cell migrationGO:0001755420.025
ubiquitin dependent protein catabolic processGO:000651130.025
cell surface receptor signaling pathwayGO:00071663250.025
apoptotic processGO:00069151160.024
single organismal cell cell adhesionGO:0016337290.024
regulation of cell growthGO:0001558290.024
tube closureGO:006060610.024
transportGO:00068102200.024
glomerular filtrationGO:000309460.024
regulation of nucleotide catabolic processGO:003081120.024
positive regulation of signal transductionGO:0009967560.024
organonitrogen compound metabolic processGO:1901564740.024
modification dependent protein catabolic processGO:001994130.023
negative regulation of mitotic cell cycleGO:0045930110.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
embryo development ending in birth or egg hatchingGO:00097922710.023
morphogenesis of an epithelial foldGO:006057110.023
foregut morphogenesisGO:000744040.023
positive regulation of transportGO:005105020.022
regulation of establishment of planar polarityGO:009017540.022
multicellular organismal homeostasisGO:0048871290.022
cellular macromolecule metabolic processGO:00442603910.022
transmission of nerve impulseGO:0019226190.022
nephron tubule morphogenesisGO:007207810.022
regulation of gtpase activityGO:004308720.022
eye photoreceptor cell differentiationGO:0001754450.022
establishment of mitotic spindle localizationGO:0040001120.021
regulation of axonogenesisGO:0050770320.021
cellular protein metabolic processGO:00442671290.021
neural plate pattern specificationGO:0060896120.021
positive regulation of cellular component biogenesisGO:004408930.021
determination of dorsal ventral asymmetryGO:0048262340.021
developmental growth involved in morphogenesisGO:0060560860.021
regulation of multicellular organismal developmentGO:20000262230.021
positive regulation of cellular amine metabolic processGO:003324000.021
regulation of cell shapeGO:000836010.020
establishment of epithelial cell polarityGO:009016220.020
wnt signaling pathway planar cell polarity pathwayGO:006007140.020
regulation of macromolecule metabolic processGO:00602553170.020
actin mediated cell contractionGO:007025210.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
polarized epithelial cell differentiationGO:003085940.020
establishment of cell polarityGO:0030010180.020
purine nucleotide metabolic processGO:0006163270.020
neuron projection developmentGO:00311751800.020
cellular response to stressGO:0033554620.020
immune system processGO:00023762410.020
collagen metabolic processGO:003296320.019
determination of left right symmetryGO:00073681790.019
cell proliferation in forebrainGO:002184630.019
axon ensheathmentGO:0008366180.019
negative regulation of gliogenesisGO:001401410.019
myeloid cell differentiationGO:0030099860.019
proteasomal protein catabolic processGO:001049820.019
regulation of anatomical structure morphogenesisGO:00226031300.018
regulation of growthGO:0040008420.018
phagocytosis engulfmentGO:000691110.018
regulation of gtp catabolic processGO:003312420.018
organic cyclic compound biosynthetic processGO:19013622230.018
neural plate developmentGO:0001840100.018
morphogenesis of an epitheliumGO:00020093330.018
regulation of programmed cell deathGO:00430671010.018
purine nucleoside monophosphate catabolic processGO:000912840.018
pigment cell differentiationGO:0050931380.018
gene expressionGO:00104672520.018
release of sequestered calcium ion into cytosolGO:005120930.018
positive regulation of catabolic processGO:000989640.018
regulation of heart growthGO:006042020.017
indole containing compound metabolic processGO:004243020.017
renal tubule morphogenesisGO:006133310.017
cellular component disassemblyGO:002241110.017
positive regulation of nucleotide catabolic processGO:003081310.017
organelle localizationGO:0051640490.017
collagen biosynthetic processGO:003296420.017
cation transportGO:0006812810.017
g2 dna damage checkpointGO:003157230.017
regulation of non canonical wnt signaling pathwayGO:200005070.017
neuromuscular process controlling balanceGO:005088530.016
positive regulation of cell adhesionGO:004578510.016
smoothened signaling pathwayGO:0007224300.016
regulation of cell substrate adhesionGO:001081010.016
heart morphogenesisGO:00030071560.016
apoptotic signaling pathwayGO:0097190230.016
regulation of ion transportGO:0043269220.016
regulation of rna biosynthetic processGO:20011412130.016
regulation of ion transmembrane transporter activityGO:003241220.016
exocrine system developmentGO:0035272280.016
negative regulation of programmed cell deathGO:0043069580.016
tissue homeostasisGO:0001894250.016
negative regulation of transcription dna templatedGO:0045892450.016
deathGO:00162651210.015
positive regulation of epithelial cell differentiationGO:003085820.015
embryonic organ developmentGO:00485683810.015
cardiac cell fate commitmentGO:006091110.015
macromolecule modificationGO:00434121110.015
mitotic g2 dna damage checkpointGO:000709530.015
regulation of nucleoside metabolic processGO:000911820.015
spermatid differentiationGO:004851520.015
cellular protein catabolic processGO:004425740.015
proximal distal pattern formationGO:000995410.015
regulation of cellular amine metabolic processGO:003323800.015
lamellipodium organizationGO:009758110.015
regulation of organ growthGO:004662030.015
determination of heart left right asymmetryGO:00613711170.015
single organism cellular localizationGO:1902580460.015
melanocyte differentiationGO:0030318260.014
nephron epithelium morphogenesisGO:007208810.014
regulation of cell developmentGO:00602841000.014
regulation of cell sizeGO:0008361290.014
negative regulation of biological processGO:00485193040.014
regulation of nervous system developmentGO:0051960900.014
somatic stem cell maintenanceGO:003501910.014
establishment of organelle localizationGO:0051656450.014
action potentialGO:0001508190.014
negative regulation of cellular component organizationGO:0051129160.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
regulation of multicellular organism growthGO:004001440.014
forebrain developmentGO:0030900960.014
regulation of cellular amino acid metabolic processGO:000652100.014
response to corticosteroidGO:003196010.014
myotube differentiationGO:0014902450.014
post anal tail morphogenesisGO:0036342190.014
stem cell proliferationGO:007208940.014
positive regulation of cell activationGO:005086710.014
multicellular organismal response to stressGO:003355520.014
nuclear divisionGO:0000280230.014
positive regulation of response to stimulusGO:0048584800.014
proximal tubule developmentGO:007201430.014
notochord developmentGO:0030903540.014
cytoskeleton dependent cytokinesisGO:006164030.014
positive regulation of stem cell proliferationGO:200064810.013
heterocycle biosynthetic processGO:00181302150.013
inner ear morphogenesisGO:0042472630.013
regulation of neuron projection developmentGO:0010975400.013
regulation of cell morphogenesisGO:0022604420.013
neural crest cell developmentGO:0014032620.013
basement membrane assemblyGO:007083130.013
centrosome organizationGO:005129710.013
mesenchyme developmentGO:00604851270.013
sequestering of calcium ionGO:005120830.013
embryonic skeletal joint developmentGO:007249830.013
positive regulation of cellular catabolic processGO:003133130.013
regulation of developmental processGO:00507932470.013
negative regulation of signalingGO:0023057960.013
positive regulation of leukocyte differentiationGO:190210710.013
positive regulation of cell cycleGO:004578730.013
signal transduction in absence of ligandGO:003803410.013
embryonic camera type eye morphogenesisGO:0048596190.013
regulation of transmembrane transporter activityGO:002289820.013
regulation of gene expressionGO:00104682650.013
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573710.013
regulation of cell morphogenesis involved in differentiationGO:0010769380.013
axis elongation involved in somitogenesisGO:009024520.013
skin developmentGO:0043588540.012
establishment of protein localization to organelleGO:007259440.012
regulation of sequestering of calcium ionGO:005128240.012
stem cell developmentGO:0048864820.012
negative regulation of nuclear divisionGO:005178430.012
mediolateral intercalationGO:006003130.012
lymphocyte proliferationGO:004665110.012
positive regulation of epithelial cell migrationGO:001063420.012
regulation of catalytic activityGO:0050790550.012
regulation of leukocyte mediated immunityGO:000270310.012
cell migrationGO:00164772370.012
fin morphogenesisGO:0033334530.012
regulation of cellular protein catabolic processGO:190336210.012
kidney vasculature developmentGO:006144020.012
regulation of glial cell differentiationGO:004568540.012
regulation of protein ubiquitinationGO:003139630.012
cellular nitrogen compound catabolic processGO:0044270150.012
cellular response to nutrient levelsGO:003166920.012
intracellular signal transductionGO:0035556850.012
regulation of anatomical structure sizeGO:0090066330.012
purine ribonucleotide metabolic processGO:0009150270.012
regulation of synapse assemblyGO:005196330.012
ventral spinal cord interneuron fate commitmentGO:006057930.012
central nervous system neuron differentiationGO:0021953740.012
organic substance catabolic processGO:1901575280.012
gall bladder developmentGO:006101010.012
embryonic appendage morphogenesisGO:0035113300.012
purine ribonucleotide catabolic processGO:000915460.012
transcription dna templatedGO:00063511810.012
regulation of blood pressureGO:000821710.012
establishment of apical basal cell polarityGO:003508920.012
maintenance of gastrointestinal epitheliumGO:003027770.012
positive regulation of cell matrix adhesionGO:000195410.011
photoreceptor cell fate specificationGO:004370410.011
outflow tract morphogenesisGO:000315110.011
brain segmentationGO:003528460.011
response to abiotic stimulusGO:00096281220.011
nucleobase containing compound biosynthetic processGO:00346542050.011
nephron morphogenesisGO:007202820.011
regulation of calcium ion transportGO:005192420.011
cellular catabolic processGO:0044248270.011
rho protein signal transductionGO:000726650.011
development of primary female sexual characteristicsGO:004654540.011
epithelial cilium movementGO:0003351150.011
ensheathment of neuronsGO:0007272180.011
neural plate regionalizationGO:0060897100.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
catecholamine metabolic processGO:000658420.011
cellular amine metabolic processGO:004410620.011
amine metabolic processGO:000930820.011
nucleobase containing compound catabolic processGO:0034655150.011
establishment of spindle localizationGO:0051293120.011
tube morphogenesisGO:00352393490.011
positive regulation of muscle organ developmentGO:004863610.011
positive regulation of signalingGO:0023056560.011
regulation of ras gtpase activityGO:003231820.011
mitotic g2 m transition checkpointGO:004481830.011
cytosolic calcium ion transportGO:006040130.011
female gonad developmentGO:000858540.011
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.011
axial mesoderm developmentGO:0048318100.011
cellular amino acid metabolic processGO:000652070.011
regulation of cell projection organizationGO:0031344440.011
meiotic cell cycle processGO:190304630.011
fertilizationGO:000956630.010
regulation of rho gtpase activityGO:003231910.010
organic substance biosynthetic processGO:19015762890.010
apoptotic process involved in morphogenesisGO:006056120.010
organ regenerationGO:003110010.010
endocardium morphogenesisGO:000316040.010
regulation of mrna processingGO:005068430.010
protein depolymerizationGO:005126110.010
cellular nitrogen compound metabolic processGO:00346412900.010
heterocycle metabolic processGO:00464832900.010
cell matrix adhesionGO:000716040.010
posttranscriptional gene silencingGO:001644130.010
modification dependent macromolecule catabolic processGO:004363230.010
eye photoreceptor cell developmentGO:0042462300.010
regulation of hormone levelsGO:0010817210.010
neural plate morphogenesisGO:000183970.010
ras protein signal transductionGO:000726570.010
dorsal motor nucleus of vagus nerve developmentGO:002174440.010
cellular amide metabolic processGO:004360340.010

lrp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
musculoskeletal system diseaseDOID:1700.014
diabetes mellitusDOID:935100.012
type 2 diabetes mellitusDOID:935200.012
disease of metabolismDOID:001466700.012
acquired metabolic diseaseDOID:006015800.012
carbohydrate metabolism diseaseDOID:005001300.012
glucose metabolism diseaseDOID:419400.012
connective tissue diseaseDOID:6500.012
bone development diseaseDOID:008000600.012
bone diseaseDOID:008000100.012
osteochondrodysplasiaDOID:225600.012