Danio rerio

0 known processes

trio

triple functional domain (PTPRF interacting)

(Aliases: si:dz230d15.1)

trio biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.076
maintenance of locationGO:005123540.040
phagocytosisGO:000690930.038
agingGO:000756820.038
signal transductionGO:00071654550.037
cell surface receptor signaling pathwayGO:00071663250.035
regulation of multicellular organism growthGO:004001440.035
positive regulation of cellular component biogenesisGO:004408930.035
amine metabolic processGO:000930820.034
cellular macromolecule metabolic processGO:00442603910.033
positive regulation of cell cycleGO:004578730.032
cellular amine metabolic processGO:004410620.031
nitrogen compound metabolic processGO:00068073190.031
positive regulation of transportGO:005105020.031
cellular nitrogen compound metabolic processGO:00346412900.031
multicellular organism growthGO:003526440.030
cellular protein catabolic processGO:004425740.030
meiotic nuclear divisionGO:000712640.029
organic cyclic compound metabolic processGO:19013603010.029
regulation of cellular metabolic processGO:00313233200.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
lipid storageGO:001991510.028
extrinsic apoptotic signaling pathwayGO:009719130.028
sensory organ developmentGO:00074233930.027
regulation of cellular amino acid metabolic processGO:000652100.027
stem cell maintenanceGO:001982740.027
cellular ketone metabolic processGO:0042180110.027
regulation of cellular amine metabolic processGO:003323800.026
establishment of protein localization to organelleGO:007259440.026
regulation of establishment of protein localizationGO:007020140.026
eye developmentGO:00016542770.026
positive regulation of protein complex assemblyGO:003133420.026
regulation of cytokine productionGO:000181730.025
negative regulation of cellular processGO:00485232830.025
regulation of cell activationGO:005086510.025
regulation of metabolic processGO:00192223590.025
regulation of protein transportGO:005122330.025
regulation of signal transductionGO:00099662250.025
regulation of cellular ketone metabolic processGO:001056570.025
mitochondrion organizationGO:000700540.024
modification dependent macromolecule catabolic processGO:004363230.024
immune system processGO:00023762410.024
cellular aromatic compound metabolic processGO:00067252950.024
nucleobase containing compound metabolic processGO:00061392740.024
ribonucleoside monophosphate catabolic processGO:000915840.024
atp catabolic processGO:000620040.024
female sex differentiationGO:004666040.024
adult behaviorGO:003053420.024
response to chemicalGO:00422213200.024
heterocycle metabolic processGO:00464832900.023
organonitrogen compound metabolic processGO:1901564740.023
gene expressionGO:00104672520.023
rna metabolic processGO:00160702190.023
organic substance biosynthetic processGO:19015762890.023
regulation of response to stimulusGO:00485832690.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
negative regulation of protein phosphorylationGO:000193340.022
autophagyGO:000691440.022
nucleic acid metabolic processGO:00903042440.022
modification dependent protein catabolic processGO:001994130.022
positive regulation of catabolic processGO:000989640.022
cell substrate adhesionGO:003158940.022
erk1 and erk2 cascadeGO:007037140.022
protein acetylationGO:000647320.022
regulation of gene expressionGO:00104682650.022
regulation of nitrogen compound metabolic processGO:00511712510.022
generation of neuronsGO:00486993850.022
heterocycle biosynthetic processGO:00181302150.022
cellular response to external stimulusGO:007149620.022
proteasomal protein catabolic processGO:001049820.021
negative regulation of biological processGO:00485193040.021
regulation of signalingGO:00230512350.021
response to drugGO:004249330.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
regulation of primary metabolic processGO:00800903110.021
nuclear transportGO:005116940.021
regulation of erk1 and erk2 cascadeGO:007037240.021
hemopoiesisGO:00300971830.021
oxoacid metabolic processGO:0043436310.020
cellular component movementGO:00069283350.020
blood vessel developmentGO:00015682460.020
positive regulation of cytokine productionGO:000181920.020
meiotic cell cycle processGO:190304630.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
regulation of reproductive processGO:200024140.020
positive regulation of secretionGO:005104710.020
nucleoside monophosphate catabolic processGO:000912540.020
gtp catabolic processGO:000618420.020
cellular response to extracellular stimulusGO:003166820.020
regulation of protein complex assemblyGO:004325430.020
carboxylic acid metabolic processGO:0019752220.020
regulation of protein catabolic processGO:004217610.020
biosynthetic processGO:00090582940.020
organic acid metabolic processGO:0006082310.020
cellular macromolecule biosynthetic processGO:00346452240.020
purine ribonucleoside monophosphate catabolic processGO:000916940.019
membrane fusionGO:006102520.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
regulation of cell communicationGO:00106462320.019
cellular amino acid metabolic processGO:000652070.019
cognitionGO:005089010.019
locomotor rhythmGO:004547530.019
cellular response to nutrient levelsGO:003166920.019
guanosine containing compound metabolic processGO:190106840.019
ubiquitin dependent protein catabolic processGO:000651130.019
regulation of macromolecule biosynthetic processGO:00105562250.019
peptidyl lysine acetylationGO:001839420.019
camera type eye developmentGO:00430102220.019
vasculature developmentGO:00019442780.019
cellular component morphogenesisGO:00329893360.019
neuron differentiationGO:00301823530.019
nucleocytoplasmic transportGO:000691340.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
regulation of multicellular organismal processGO:00512392770.019
positive regulation of cytoskeleton organizationGO:005149530.019
localization of cellGO:00516742440.019
guanosine containing compound catabolic processGO:190106920.019
regulation of inflammatory responseGO:005072720.019
regulation of biosynthetic processGO:00098892500.019
cell part morphogenesisGO:00329902460.019
positive regulation of cellular amine metabolic processGO:003324000.019
organic cyclic compound biosynthetic processGO:19013622230.019
cell morphogenesisGO:00009022890.018
cytokinesisGO:000091030.018
exocytosisGO:000688710.018
nucleobase containing compound biosynthetic processGO:00346542050.018
small molecule metabolic processGO:0044281770.018
leukocyte proliferationGO:007066110.018
morphogenesis of an epitheliumGO:00020093330.018
single organism metabolic processGO:00447102170.018
gtp metabolic processGO:004603940.018
cell projection morphogenesisGO:00488582440.018
immune system developmentGO:00025201910.018
regulation of cytoplasmic transportGO:190364940.018
establishment of localizationGO:00512342440.018
cellular response to chemical stimulusGO:00708871570.018
regulation of biological qualityGO:00650082630.018
rna biosynthetic processGO:00327741810.018
internal peptidyl lysine acetylationGO:001839320.018
synaptic growth at neuromuscular junctionGO:005112420.018
regulation of meiotic cell cycleGO:005144510.018
regulation of macromolecule metabolic processGO:00602553170.018
aromatic compound biosynthetic processGO:00194382170.018
protein localization to plasma membraneGO:007265910.018
transcription dna templatedGO:00063511810.018
regulation of synapse organizationGO:005080730.018
purine nucleoside monophosphate catabolic processGO:000912840.018
regulation of metal ion transportGO:001095940.018
embryo development ending in birth or egg hatchingGO:00097922710.018
adherens junction organizationGO:003433240.017
digestive system developmentGO:00551232890.017
tissue remodelingGO:004877140.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
blood vessel morphogenesisGO:00485142160.017
cell cycle g1 s phase transitionGO:004484310.017
regulation of bindingGO:005109830.017
negative regulation of mapk cascadeGO:004340940.017
regulation of purine nucleotide catabolic processGO:003312120.017
cellular biosynthetic processGO:00442492860.017
protein acylationGO:004354330.017
central nervous system developmentGO:00074173870.017
cytoskeleton dependent cytokinesisGO:006164030.017
tube morphogenesisGO:00352393490.017
single organism localizationGO:19025782250.017
endosomal transportGO:001619720.017
nucleic acid templated transcriptionGO:00976591810.017
regulation of mrna processingGO:005068430.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
compound eye developmentGO:004874920.016
mononuclear cell proliferationGO:003294310.016
single organism membrane fusionGO:004480120.016
embryonic organ developmentGO:00485683810.016
cell projection organizationGO:00300302840.016
regulation of rna biosynthetic processGO:20011412130.016
regulation of stem cell proliferationGO:007209120.016
positive regulation of secretion by cellGO:190353210.016
internal protein amino acid acetylationGO:000647520.016
response to organic substanceGO:00100331530.016
negative regulation of kinase activityGO:003367340.016
protein localization to nucleusGO:003450430.016
muscle structure developmentGO:00610611960.016
regulation of multicellular organismal developmentGO:20000262230.016
double strand break repairGO:000630230.016
cell migrationGO:00164772370.016
protein secretionGO:000930610.016
stem cell proliferationGO:007208940.016
organelle organizationGO:00069962270.016
primary neural tube formationGO:001402010.016
protein metabolic processGO:00195381830.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
regulation of nucleoside metabolic processGO:000911820.016
lymphocyte proliferationGO:004665110.016
response to stressGO:00069502630.016
lateral inhibitionGO:004633110.016
locomotionGO:00400113130.016
rna localizationGO:000640340.015
chordate embryonic developmentGO:00430092710.015
regulation of neural precursor cell proliferationGO:200017730.015
head developmentGO:00603223030.015
regulation of synapse assemblyGO:005196330.015
macromolecule biosynthetic processGO:00090592270.015
response to uvGO:000941130.015
positive regulation of cell adhesionGO:004578510.015
positive regulation of cellular catabolic processGO:003133130.015
germ line stem cell maintenanceGO:003071820.015
regulation of rna metabolic processGO:00512522240.015
positive regulation of biological processGO:00485182530.015
protein importGO:001703830.015
nuclear importGO:005117030.015
negative regulation of catabolic processGO:000989530.015
peptidyl serine modificationGO:001820920.015
transcription from rna polymerase ii promoterGO:0006366800.015
regulation of autophagyGO:001050630.015
establishment of protein localization to plasma membraneGO:009000210.015
g1 s transition of mitotic cell cycleGO:000008210.015
phagocytosis engulfmentGO:000691110.015
regionalizationGO:00030022740.015
cellular carbohydrate metabolic processGO:004426240.015
negative regulation of sequestering of calcium ionGO:005128340.015
positive regulation of erk1 and erk2 cascadeGO:007037420.015
angiogenesisGO:00015251580.015
regulation of cellular biosynthetic processGO:00313262450.015
negative regulation of mitosisGO:004583930.015
sequestering of metal ionGO:005123830.015
lipid homeostasisGO:005508830.014
protein dephosphorylationGO:000647030.014
cell motilityGO:00488702440.014
membrane invaginationGO:001032410.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
regulation of developmental processGO:00507932470.014
microtubule organizing center organizationGO:003102310.014
signal transduction in absence of ligandGO:003803410.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
negative regulation of cytokine productionGO:000181810.014
protein polymerizationGO:005125840.014
cytokinetic processGO:003250620.014
stem cell divisionGO:001714510.014
neuron developmentGO:00486662620.014
negative regulation of protein kinase activityGO:000646940.014
regulation of transcription dna templatedGO:00063552130.014
fertilizationGO:000956630.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of nucleotide catabolic processGO:003081120.014
positive regulation of immune effector processGO:000269930.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
anterior posterior pattern specificationGO:00099521520.014
peptidyl serine phosphorylationGO:001810510.014
digestive tract developmentGO:00485652650.014
heart developmentGO:00075073130.014
cellular component disassemblyGO:002241110.014
regulation of protein ubiquitinationGO:003139630.014
regulation of oocyte developmentGO:006028130.014
nuclear exportGO:005116810.013
cellular protein metabolic processGO:00442671290.013
single organism transportGO:00447652060.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
retina development in camera type eyeGO:00600411460.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
protein targeting to nucleusGO:004474430.013
positive regulation of cellular processGO:00485222010.013
regulation of epithelial cell proliferationGO:005067830.013
positive regulation of dna metabolic processGO:005105410.013
transportGO:00068102200.013
protein import into nucleusGO:000660630.013
regulation of intracellular protein transportGO:003315730.013
single organism organelle organizationGO:19025891990.013
small molecule catabolic processGO:004428230.013
cell cycle arrestGO:000705010.013
cellular response to starvationGO:000926710.013
brain developmentGO:00074202930.013
development of primary female sexual characteristicsGO:004654540.013
programmed cell deathGO:00125011190.013
regulation of jak stat cascadeGO:004642530.013
regulation of dna replicationGO:000627530.013
regulation of cellular protein catabolic processGO:190336210.013
release of sequestered calcium ion into cytosolGO:005120930.013
skeletal system developmentGO:00015011810.013
regulation of cell substrate adhesionGO:001081010.013
developmental programmed cell deathGO:001062340.013
mitotic cytokinesisGO:000028130.013
cell deathGO:00082191210.012
recombinational repairGO:000072510.012
chemosensory behaviorGO:000763510.012
spermatid differentiationGO:004851520.012
response to corticosteroidGO:003196010.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
cell morphogenesis involved in differentiationGO:00009041950.012
single fertilizationGO:000733830.012
cytosolic calcium ion transportGO:006040130.012
regulation of response to extracellular stimulusGO:003210410.012
centrosome duplicationGO:005129810.012
positive regulation of stress activated mapk cascadeGO:003287430.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
organelle fusionGO:004828430.012
sensory organ morphogenesisGO:00905962000.012
protein homooligomerizationGO:005126030.012
regulation of nucleocytoplasmic transportGO:004682220.012
positive regulation of cell activationGO:005086710.012
regulation of gtp catabolic processGO:003312420.012
striated muscle tissue developmentGO:00147061100.012
cellular response to oxygen levelsGO:007145310.012
spermatid developmentGO:000728620.012
female gonad developmentGO:000858540.012
inositol lipid mediated signalingGO:004801720.012
regulation of gtpase activityGO:004308720.012
deathGO:00162651210.012
sequestering of calcium ionGO:005120830.012
actin polymerization or depolymerizationGO:000815420.012
single organism nuclear importGO:190259330.012
regulation of cell shapeGO:000836010.012
neuron projection morphogenesisGO:00488121610.012
negative regulation of response to stimulusGO:00485851040.012
i kappab kinase nf kappab signalingGO:000724940.012
cellular response to organic substanceGO:00713101050.012
glucose homeostasisGO:004259310.012
tube closureGO:006060610.012
golgi vesicle transportGO:004819330.012
response to carbohydrateGO:000974330.012
phosphorus metabolic processGO:00067931090.012
response to nutrientGO:000758430.012
regulation of dendrite developmentGO:005077330.012
macromolecule modificationGO:00434121110.012
response to monosaccharideGO:003428430.012
system processGO:00030081850.012
regulation of stem cell differentiationGO:200073640.012
regulation of sequestering of calcium ionGO:005128240.012
calcium ion transport into cytosolGO:006040230.012
regulation of calcium ion transportGO:005192420.012
secondary metabolic processGO:001974830.012
response to hexoseGO:000974630.012
convergent extensionGO:00600261180.012
positive regulation of map kinase activityGO:004340630.012
actin filament polymerizationGO:003004120.012
positive regulation of response to stimulusGO:0048584800.012
phosphate containing compound metabolic processGO:00067961080.011
positive regulation of nucleotide catabolic processGO:003081310.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
cell matrix adhesionGO:000716040.011
negative regulation of cellular catabolic processGO:003133030.011
organic acid catabolic processGO:001605430.011
intracellular mrna localizationGO:000829810.011
response to endogenous stimulusGO:0009719830.011
carbohydrate homeostasisGO:003350010.011
protein heterooligomerizationGO:005129110.011
ion transmembrane transportGO:0034220910.011
negative regulation of nuclear divisionGO:005178430.011
gastrulationGO:00073692080.011
axonogenesisGO:00074091520.011
erythrocyte homeostasisGO:0034101550.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
determination of bilateral symmetryGO:00098552040.011
b cell activationGO:004211320.011
nucleic acid transportGO:005065720.011
negative regulation of defense responseGO:003134820.011
cell substrate junction assemblyGO:000704420.011
viral processGO:001603210.011
negative regulation of signal transductionGO:0009968940.011
neurotransmitter transportGO:000683620.011
intracellular signal transductionGO:0035556850.011
protein polyubiquitinationGO:000020940.011
response to external stimulusGO:00096052640.011
membrane lipid biosynthetic processGO:004646720.011
digestive tract morphogenesisGO:00485462310.011
protein modification processGO:00362111000.011
regulation of mrna splicing via spliceosomeGO:004802430.011
cellular response to biotic stimulusGO:007121630.011
cellular response to radiationGO:007147840.011
interspecies interaction between organismsGO:004441940.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
muscle cell differentiationGO:00426921390.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
macromolecular complex disassemblyGO:003298410.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
macroautophagyGO:001623610.011
cellular response to hypoxiaGO:007145610.011
multi organism cellular processGO:004476420.011
regulation of protein localization to nucleusGO:190018020.010
positive regulation of translationGO:004572710.010
developmental growthGO:00485891660.010
regulation of wound healingGO:006104120.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
positive regulation of nucleoside metabolic processGO:004597910.010
cellular protein modification processGO:00064641000.010
centrosome organizationGO:005129710.010
regulation of protein import into nucleusGO:004230620.010
production of molecular mediator of immune responseGO:000244020.010
meiotic chromosome segregationGO:004513230.010
regulation of protein localization to plasma membraneGO:190307610.010
protein complex disassemblyGO:004324110.010
regulation of protein targetingGO:190353320.010
eye morphogenesisGO:00485921440.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
negative regulation of protein transportGO:005122430.010
somatic muscle developmentGO:000752540.010
cortical cytoskeleton organizationGO:003086510.010
dorsal ventral pattern formationGO:00099531250.010
regulation of apoptotic processGO:0042981980.010
regulation of dendrite morphogenesisGO:004881430.010
response to hydrogen peroxideGO:004254230.010
response to ketoneGO:190165410.010
wnt signaling pathwayGO:0016055800.010

trio disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.020
musculoskeletal system diseaseDOID:1700.020
disease of metabolismDOID:001466700.017
nervous system diseaseDOID:86300.017
immune system diseaseDOID:291400.014
connective tissue diseaseDOID:6500.010
muscular diseaseDOID:008000000.010