Danio rerio

0 known processes

pax4

paired box 4

(Aliases: si:dkey-146j3.3)

pax4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.340
pancreas developmentGO:0031016840.316
endocrine system developmentGO:0035270650.247
neuron developmentGO:00486662620.220
embryonic cranial skeleton morphogenesisGO:0048701900.194
endocrine pancreas developmentGO:0031018270.173
adult behaviorGO:003053420.171
pancreatic a cell developmentGO:000332220.142
neuron differentiationGO:00301823530.142
determination of bilateral symmetryGO:00098552040.109
head developmentGO:00603223030.108
type b pancreatic cell differentiationGO:000330980.102
behaviorGO:0007610740.100
skeletal system developmentGO:00015011810.100
skeletal muscle organ developmentGO:0060538780.096
cellular macromolecule biosynthetic processGO:00346452240.096
pancreatic d cell differentiationGO:000331120.096
central nervous system myelinationGO:002201020.096
type b pancreatic cell developmentGO:000332340.090
regulation of macromolecule metabolic processGO:00602553170.087
regionalizationGO:00030022740.087
nitrogen compound metabolic processGO:00068073190.085
specification of symmetryGO:00097992040.084
response to external stimulusGO:00096052640.080
cellular nitrogen compound metabolic processGO:00346412900.080
heart developmentGO:00075073130.074
skeletal system morphogenesisGO:00487051020.074
eye morphogenesisGO:00485921440.073
regulation of gene expressionGO:00104682650.072
axon ensheathment in central nervous systemGO:003229120.072
hormone transportGO:000991420.071
organic cyclic compound biosynthetic processGO:19013622230.070
axonogenesisGO:00074091520.068
regulation of biological qualityGO:00650082630.068
neuron projection developmentGO:00311751800.064
gene expressionGO:00104672520.063
enteroendocrine cell differentiationGO:003588390.063
axon developmentGO:00615641660.062
regulation of localizationGO:00328791040.060
response to stressGO:00069502630.059
nuclear transportGO:005116940.059
compound eye developmentGO:004874920.058
determination of left right symmetryGO:00073681790.057
aromatic compound biosynthetic processGO:00194382170.056
generation of neuronsGO:00486993850.055
biosynthetic processGO:00090582940.055
nucleobase containing compound metabolic processGO:00061392740.054
phagocytosisGO:000690930.054
response to chemicalGO:00422213200.053
central nervous system developmentGO:00074173870.053
response to organic substanceGO:00100331530.052
organic cyclic compound metabolic processGO:19013603010.052
negative regulation of response to stimulusGO:00485851040.051
chemotaxisGO:00069351040.050
cell projection organizationGO:00300302840.050
embryonic organ morphogenesisGO:00485622740.050
dorsal ventral pattern formationGO:00099531250.050
regulation of hormone secretionGO:004688320.049
peptide transportGO:001583310.049
stem cell maintenanceGO:001982740.049
cell growthGO:0016049570.048
cell fate specification involved in pattern specificationGO:006057330.047
hormone secretionGO:004687920.047
regulation of developmental processGO:00507932470.047
gabaergic neuron differentiationGO:009715420.046
development of primary female sexual characteristicsGO:004654540.046
positive regulation of cellular processGO:00485222010.046
columnar cuboidal epithelial cell differentiationGO:0002065380.046
localization of cellGO:00516742440.045
multicellular organismal signalingGO:0035637220.045
cellular component movementGO:00069283350.044
establishment of localizationGO:00512342440.044
system processGO:00030081850.044
regulation of organ growthGO:004662030.043
gland developmentGO:00487321430.042
embryonic skeletal system morphogenesisGO:0048704930.042
cell part morphogenesisGO:00329902460.042
regulation of signalingGO:00230512350.042
regulation of metabolic processGO:00192223590.041
lateral inhibitionGO:004633110.041
positive regulation of cellular component biogenesisGO:004408930.041
regulation of multicellular organismal developmentGO:20000262230.041
cell cycle g1 s phase transitionGO:004484310.040
central nervous system myelin formationGO:003228910.040
negative regulation of cellular processGO:00485232830.039
nucleic acid templated transcriptionGO:00976591810.039
dendrite guidanceGO:007098300.038
cellular aromatic compound metabolic processGO:00067252950.037
response to nicotineGO:003509420.036
glandular epithelial cell differentiationGO:000206790.036
larval developmentGO:000216420.036
neuromuscular process controlling balanceGO:005088530.036
neuron projection guidanceGO:0097485860.036
positive regulation of transportGO:005105020.036
cell morphogenesisGO:00009022890.035
cell morphogenesis involved in neuron differentiationGO:00486671630.035
cell differentiation in spinal cordGO:0021515400.035
mitochondrion organizationGO:000700540.035
cellular component morphogenesisGO:00329893360.035
regulation of response to stimulusGO:00485832690.035
striated muscle tissue developmentGO:00147061100.035
embryonic skeletal system developmentGO:0048706970.035
negative regulation of biological processGO:00485193040.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
rna biosynthetic processGO:00327741810.034
female sex differentiationGO:004666040.034
transcription dna templatedGO:00063511810.034
outflow tract morphogenesisGO:000315110.034
cellular biosynthetic processGO:00442492860.033
organic substance biosynthetic processGO:19015762890.033
water homeostasisGO:003010440.033
mesenchyme developmentGO:00604851270.032
amine metabolic processGO:000930820.032
regulation of cell motilityGO:2000145460.032
embryo development ending in birth or egg hatchingGO:00097922710.032
sensory perception of painGO:001923310.032
nucleic acid metabolic processGO:00903042440.032
heterocycle metabolic processGO:00464832900.032
cellular ketone metabolic processGO:0042180110.031
glucose homeostasisGO:004259310.031
cellular amine metabolic processGO:004410620.031
rna metabolic processGO:00160702190.031
lens development in camera type eyeGO:0002088220.031
regulation of cellular macromolecule biosynthetic processGO:20001122220.031
regulation of blood pressureGO:000821710.031
carbohydrate homeostasisGO:003350010.030
response to drugGO:004249330.030
cell migrationGO:00164772370.030
negative regulation of cell communicationGO:0010648960.030
stem cell differentiationGO:00488631170.030
embryonic viscerocranium morphogenesisGO:0048703520.030
sleepGO:003043110.030
muscle cell differentiationGO:00426921390.029
single organism localizationGO:19025782250.029
regulation of phGO:000688530.029
cell projection morphogenesisGO:00488582440.028
nitrogen compound transportGO:0071705230.028
skin developmentGO:0043588540.028
regulation of cell communicationGO:00106462320.027
regulation of vascular permeabilityGO:004311450.027
heterocycle biosynthetic processGO:00181302150.027
regulation of cellular amino acid metabolic processGO:000652100.027
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.027
hatching gland developmentGO:004878530.027
regulation of nitrogen compound metabolic processGO:00511712510.027
positive regulation of cellular amine metabolic processGO:003324000.027
cellular protein catabolic processGO:004425740.026
regulation of rna biosynthetic processGO:20011412130.026
signal transductionGO:00071654550.026
muscle tissue developmentGO:00605371100.026
cellular macromolecule metabolic processGO:00442603910.026
axon guidanceGO:0007411860.026
regulation of cellular amine metabolic processGO:003323800.026
negative regulation of signalingGO:0023057960.026
circulatory system processGO:0003013870.025
cerebellar granular layer formationGO:002168430.025
epidermal cell fate specificationGO:000995740.025
cellular amino acid metabolic processGO:000652070.025
cellular response to external stimulusGO:007149620.025
erk1 and erk2 cascadeGO:007037140.025
regulation of systemic arterial blood pressureGO:000307310.025
transportGO:00068102200.025
skeletal muscle tissue developmentGO:0007519670.024
taxisGO:00423301090.024
ventral spinal cord interneuron specificationGO:002152130.024
positive regulation of dna metabolic processGO:005105410.024
regulation of signal transductionGO:00099662250.024
sensory organ developmentGO:00074233930.024
mesenchymal cell developmentGO:0014031780.024
response to endogenous stimulusGO:0009719830.023
rhombomere 6 developmentGO:002157240.023
morphogenesis of an epithelial sheetGO:0002011490.023
negative regulation of signal transductionGO:0009968940.023
ventral spinal cord interneuron fate commitmentGO:006057930.023
neural tube patterningGO:0021532330.023
protein metabolic processGO:00195381830.023
positive regulation of secretion by cellGO:190353210.023
organic substance transportGO:0071702580.023
regulation of anatomical structure morphogenesisGO:00226031300.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
cranial ganglion developmentGO:006155030.022
muscle organ developmentGO:00075171010.022
rhombomere 5 developmentGO:002157140.022
nucleocytoplasmic transportGO:000691340.022
regulation of glial cell differentiationGO:004568540.022
synaptic target recognitionGO:000803910.022
glial cell migrationGO:000834730.022
oxoacid metabolic processGO:0043436310.022
wnt signaling pathwayGO:0016055800.022
regulation of multicellular organism growthGO:004001440.021
sensory organ morphogenesisGO:00905962000.021
stem cell divisionGO:001714510.021
muscle structure developmentGO:00610611960.021
regulation of bindingGO:005109830.021
phosphatidylinositol 3 kinase signalingGO:001406520.021
developmental growthGO:00485891660.021
embryonic eye morphogenesisGO:0048048300.020
embryonic organ developmentGO:00485683810.020
wound healingGO:0042060900.020
cell morphogenesis involved in differentiationGO:00009041950.020
cellular response to extracellular stimulusGO:003166820.020
cation transmembrane transportGO:0098655650.020
organic acid metabolic processGO:0006082310.020
regulation of biosynthetic processGO:00098892500.020
regulation of synapse assemblyGO:005196330.020
regulation of cell growthGO:0001558290.020
cellular amide metabolic processGO:004360340.020
neurotransmitter transportGO:000683620.020
cell surface receptor signaling pathwayGO:00071663250.020
cellular response to chemical stimulusGO:00708871570.020
sympathetic nervous system developmentGO:004848530.020
locomotionGO:00400113130.020
inner ear developmentGO:00488391260.020
regulation of multicellular organismal processGO:00512392770.020
negative regulation of metabolic processGO:0009892860.019
positive regulation of biological processGO:00485182530.019
motor neuron axon guidanceGO:0008045230.019
nucleobase containing compound biosynthetic processGO:00346542050.019
blood circulationGO:0008015870.019
regulation of protein ubiquitinationGO:003139630.019
regulation of cell activationGO:005086510.019
catechol containing compound metabolic processGO:000971220.019
regulation of protein bindingGO:004339330.019
hindbrain developmentGO:0030902910.019
ion transmembrane transportGO:0034220910.019
response to corticosteroidGO:003196010.019
positive regulation of cell cycleGO:004578730.018
heart contractionGO:0060047710.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
sensory perception of chemical stimulusGO:000760630.018
stem cell proliferationGO:007208940.018
midbrain hindbrain boundary developmentGO:0030917230.018
protein secretionGO:000930610.018
embryonic heart tube developmentGO:00350501330.018
multicellular organism growthGO:003526440.018
cellular response to nutrient levelsGO:003166920.018
brain developmentGO:00074202930.017
regulation of cellular component movementGO:0051270550.017
canonical wnt signaling pathwayGO:0060070480.017
regulation of synapse organizationGO:005080730.017
deathGO:00162651210.017
olfactory bulb developmentGO:002177240.017
neuroblast proliferationGO:000740520.017
regulation of erk1 and erk2 cascadeGO:007037240.017
meiotic nuclear divisionGO:000712640.017
developmental programmed cell deathGO:001062340.017
regenerationGO:0031099910.017
response to woundingGO:00096111160.017
macromolecule biosynthetic processGO:00090592270.017
lipid storageGO:001991510.017
protein localization to plasma membraneGO:007265910.017
cellular response to starvationGO:000926710.017
regulation of reproductive processGO:200024140.017
regulation of establishment of protein localizationGO:007020140.017
response to alkaloidGO:004327920.017
positive regulation of cellular catabolic processGO:003133130.017
positive regulation of cell fate commitmentGO:001045510.016
photoreceptor cell fate commitmentGO:004655210.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
pancreatic a cell differentiationGO:000331060.016
lens fiber cell developmentGO:007030730.016
appendage morphogenesisGO:0035107560.016
growthGO:00400071740.016
amino acid transportGO:000686520.016
cellular response to biotic stimulusGO:007121630.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
vasculature developmentGO:00019442780.016
regulation of cellular ketone metabolic processGO:001056570.016
alpha amino acid metabolic processGO:190160530.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
camera type eye morphogenesisGO:00485931080.016
pituitary gland developmentGO:0021983160.016
carboxylic acid metabolic processGO:0019752220.016
macroautophagyGO:001623610.016
embryonic digestive tract developmentGO:004856640.016
phosphate containing compound metabolic processGO:00067961080.016
cognitionGO:005089010.016
regulation of transcription involved in cell fate commitmentGO:006085010.016
regulation of cell migrationGO:0030334400.016
regulation of cell deathGO:00109411030.016
regulation of blood vessel sizeGO:005088020.016
regulation of protein catabolic processGO:004217610.016
endocardium morphogenesisGO:000316040.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
epidermis developmentGO:0008544480.016
negative regulation of kinase activityGO:003367340.015
myelin assemblyGO:003228810.015
regulation of neuron migrationGO:200122220.015
multicellular organismal response to stressGO:003355520.015
positive regulation of blood circulationGO:190352420.015
cardiac atrium developmentGO:000323040.015
neuron projection morphogenesisGO:00488121610.015
mesoderm developmentGO:0007498880.015
heart processGO:0003015710.015
axon extensionGO:0048675450.015
photoreceptor cell fate specificationGO:004370410.015
regulation of cellular biosynthetic processGO:00313262450.015
positive regulation of synapse assemblyGO:005196510.015
lateral line ganglion developmentGO:004889020.015
digestive system developmentGO:00551232890.015
multi organism processGO:00517041340.015
transmembrane transportGO:00550851200.015
transmission of nerve impulseGO:0019226190.015
extrinsic apoptotic signaling pathwayGO:009719130.015
positive regulation of secretionGO:005104710.015
cell fate specificationGO:0001708680.015
response to carbohydrateGO:000974330.015
sympathetic ganglion developmentGO:006154920.014
activation of mapk activityGO:000018730.014
inorganic ion transmembrane transportGO:0098660570.014
positive regulation of cell activationGO:005086710.014
establishment of protein localization to organelleGO:007259440.014
g1 s transition of mitotic cell cycleGO:000008210.014
ear developmentGO:00435831270.014
anterior posterior pattern specificationGO:00099521520.014
response to foodGO:003209410.014
cardiac atrium morphogenesisGO:000320920.014
regulation of wnt signaling pathwayGO:0030111530.014
positive regulation of response to stimulusGO:0048584800.014
response to hormoneGO:0009725480.014
guanosine containing compound metabolic processGO:190106840.014
neural tube developmentGO:0021915620.014
cell proliferationGO:0008283800.014
positive regulation of map kinase activityGO:004340630.014
positive regulation of gliogenesisGO:001401520.014
regulation of response to extracellular stimulusGO:003210410.014
epithelial cell differentiationGO:00308551160.014
single organism nuclear importGO:190259330.014
striated muscle cell differentiationGO:00511461290.014
negative regulation of gliogenesisGO:001401410.014
organelle organizationGO:00069962270.014
exocrine pancreas developmentGO:0031017280.014
response to glucoseGO:000974930.014
mesenchymal cell differentiationGO:0048762870.014
ventral spinal cord interneuron differentiationGO:0021514120.014
regulation of intracellular protein transportGO:003315730.014
exocrine system developmentGO:0035272280.014
somatic muscle developmentGO:000752540.014
single organism metabolic processGO:00447102170.014
neural plate pattern specificationGO:0060896120.014
response to uvGO:000941130.014
negative regulation of secretionGO:005104820.014
cell substrate adhesionGO:003158940.013
pigmentationGO:0043473850.013
spinal cord motor neuron differentiationGO:0021522260.013
rostrocaudal neural tube patterningGO:0021903290.013
catechol containing compound biosynthetic processGO:000971320.013
chemosensory behaviorGO:000763510.013
locomotory behaviorGO:0007626340.013
carboxylic acid biosynthetic processGO:0046394120.013
myotube differentiationGO:0014902450.013
regulation of response to nutrient levelsGO:003210710.013
positive regulation of translationGO:004572710.013
autophagyGO:000691440.013
positive regulation of catabolic processGO:000989640.013
inositol lipid mediated signalingGO:004801720.013
mononuclear cell proliferationGO:003294310.013
positive regulation of leukocyte differentiationGO:190210710.013
developmental growth involved in morphogenesisGO:0060560860.013
regulation of muscle contractionGO:000693730.013
response to hexoseGO:000974630.013
positive regulation of multicellular organismal processGO:0051240520.013
germ line stem cell maintenanceGO:003071820.013
positive regulation of jnk cascadeGO:004633030.013
cell cell signalingGO:0007267520.013
cardiac cell fate commitmentGO:006091110.013
positive regulation of cytoskeleton organizationGO:005149530.013
meiotic cell cycle processGO:190304630.012
regulation of endothelial cell differentiationGO:004560130.012
b cell activationGO:004211320.012
regulation of circadian rhythmGO:004275240.012
cell matrix adhesionGO:000716040.012
embryonic neurocranium morphogenesisGO:0048702150.012
neuronal action potentialGO:0019228180.012
single organism transportGO:00447652060.012
positive regulation of stem cell proliferationGO:200064810.012
single organism organelle organizationGO:19025891990.012
regulation of circadian sleep wake cycleGO:004274910.012
tissue migrationGO:0090130370.012
regulation of inflammatory responseGO:005072720.012
transcription from rna polymerase ii promoterGO:0006366800.012
neurological system processGO:0050877620.012
cell motilityGO:00488702440.012
tissue remodelingGO:004877140.012
embryonic camera type eye morphogenesisGO:0048596190.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
regulation of cellular component organizationGO:0051128860.012
protein importGO:001703830.012
protein targeting to nucleusGO:004474430.012
positive regulation of glial cell differentiationGO:004568710.012
neural crest cell migrationGO:0001755420.012
regulation of tube sizeGO:003515020.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
biological adhesionGO:0022610400.012
homeostatic processGO:00425921420.012
dorsal ventral axis specificationGO:0009950140.012
cerebellar granule cell differentiationGO:002170730.012
blood vessel morphogenesisGO:00485142160.012
lens fiber cell morphogenesisGO:007030930.011
chloride transmembrane transportGO:190247640.011
glial cell proliferationGO:001400940.011
membrane fusionGO:006102520.011
positive regulation of epithelial cell proliferationGO:005067910.011
neural crest cell developmentGO:0014032620.011
negative regulation of cellular biosynthetic processGO:0031327550.011
protein acetylationGO:000647320.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
renal system developmentGO:0072001940.011
neuroblast differentiationGO:001401610.011
photoreceptor cell differentiationGO:0046530550.011
stem cell developmentGO:0048864820.011
guanosine containing compound catabolic processGO:190106920.011
positive regulation of muscle cell differentiationGO:005114910.011
synaptic transmission cholinergicGO:000727140.011
negative regulation of gene expressionGO:0010629650.011
modification dependent macromolecule catabolic processGO:004363230.011
cation transportGO:0006812810.011
neural crest cell differentiationGO:0014033720.011
neutral amino acid transportGO:001580420.011
maintenance of locationGO:005123540.011
catecholamine metabolic processGO:000658420.011
oxidation reduction processGO:0055114410.011
muscle cell developmentGO:00550011150.011
regulation of canonical wnt signaling pathwayGO:0060828340.011
b cell differentiationGO:003018310.011
regulation of cell fate commitmentGO:0010453220.011
positive regulation of gtp catabolic processGO:003312610.010
regulation of gastrulationGO:0010470240.010
embryonic digestive tract morphogenesisGO:004855730.010
regulation of circadian sleep wake cycle sleepGO:004518710.010
somatic stem cell maintenanceGO:003501910.010
olfactory lobe developmentGO:002198840.010
gliogenesisGO:0042063450.010
camera type eye developmentGO:00430102220.010
response to glucocorticoidGO:005138410.010
regulation of system processGO:0044057400.010
positive regulation of cytokine productionGO:000181920.010
striated muscle cell developmentGO:00550021080.010
regulation of synaptic plasticityGO:004816710.010
immune system processGO:00023762410.010
eye developmentGO:00016542770.010
regulation of stem cell differentiationGO:200073640.010
endoderm developmentGO:0007492490.010
positive regulation of signal transductionGO:0009967560.010
peptidyl lysine acetylationGO:001839420.010
response to organic cyclic compoundGO:0014070510.010
positive regulation of muscle organ developmentGO:004863610.010
negative regulation of macromolecule biosynthetic processGO:0010558480.010
circadian sleep wake cycleGO:004274520.010
regulation of gtpase activityGO:004308720.010
agingGO:000756820.010
inorganic anion transportGO:0015698250.010

pax4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.104
musculoskeletal system diseaseDOID:1700.020
connective tissue diseaseDOID:6500.020
nervous system diseaseDOID:86300.016
bone diseaseDOID:008000100.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
sensory system diseaseDOID:005015500.011
disease of metabolismDOID:001466700.011